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Exercise, type-1 diabetes

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https://www.readbyqxmd.com/read/28104096/telemedicine-in-the-management-of-type-2-diabetes-mellitus
#1
Guixia Wang, Zhengyun Zhang, Yakun Feng, Lin Sun, Xianchao Xiao, Gang Wang, Yuan Gao, Huan Wang, Hong Zhang, Yufeng Deng, Chenglin Sun
OBJECTIVE: To explore a model of Internet-based integrated management of diabetes, we established a remote diabetes medical service platform (U-Healthcare) and evaluated its effectiveness and practicality. MATERIALS AND METHODS: In total, 212 patients with type 2 diabetes mellitus were randomly assigned to 2 groups. Data from the intervention group were automatically transmitted through a glucometer; furthermore, this group received information regarding medicines, diet, exercise and other management through U-Healthcare...
January 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/28098780/adding-salt-to-meals-as-a-risk-factor-of-type-2-diabetes-mellitus-a-case-control-study
#2
Lina Radzeviciene, Rytas Ostrauskas
OBJECTIVE: Type 2 diabetes mellitus (T2DM) is thought to arise from the complex interplay between genetic and environmental factors. It is important to identify modifiable risk factors that may help to reduce the risk of diabetes. Data on salt intake and the risk of type 2 diabetes are limited. The aim of this study was to assess the relationship between adding salt to prepared meals and the risk of type 2 diabetes. METHODS: In a case-control study, we included 234 cases, all of whom were patients aged 35-86 years with a newly confirmed diagnosis of T2DM, and 468 controls that were free of the disease...
January 13, 2017: Nutrients
https://www.readbyqxmd.com/read/28097367/impaired-glucose-homeostasis-in-first-episode-schizophrenia-a-systematic-review-and-meta-analysis
#3
Toby Pillinger, Katherine Beck, Cristian Gobjila, Jacek G Donocik, Sameer Jauhar, Oliver D Howes
Importance: Schizophrenia is associated with an increased risk of type 2 diabetes. However, it is not clear whether schizophrenia confers an inherent risk for glucose dysregulation in the absence of the effects of chronic illness and long-term treatment. Objective: To conduct a meta-analysis examining whether individuals with first-episode schizophrenia already exhibit alterations in glucose homeostasis compared with controls. Data Sources: The EMBASE, MEDLINE, and PsycINFO databases were systematically searched for studies examining measures of glucose homeostasis in antipsychotic-naive individuals with first-episode schizophrenia compared with individuals serving as controls...
January 11, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28093924/effects-of-an-adapted-cardiac-rehabilitation-programme-on-arterial-stiffness-in-patients-with-type-2-diabetes-without-cardiac-disease-diagnosis
#4
Anka P Brozic, Susan Marzolini, Jack M Goodman
PURPOSE: To determine the effects of a 12-week cardiac rehabilitation programme of aerobic and resistance exercise training on arterial stiffness, peak calf vasodilatory reserve, and haemostatic markers in patients with type 2 diabetes. METHODS: Observational cohort study examining effects of 12 weeks of exercise training in 23 subjects (13 men, 10 women; mean age of 56.1 ± 10.1 years) with type 2 diabetes mellitus. Subjects performed exercise training for 12 weeks [aerobic training 5 days/week, 70%-75% peak cardiovascular fitness (VO2peak) and resistance training 2-3 days/week, 60% of one repetition maximum]...
January 1, 2017: Diabetes & Vascular Disease Research
https://www.readbyqxmd.com/read/28090231/effects-of-ipragliflozin-on-diabetic-nephropathy-and-blood-pressure-in-patients-with-type-2-diabetes-an-open-label-study
#5
Daisuke Ito, Emi Ikuma-Suwa, Kazuyuki Inoue, Kimie Kaneko, Morifumi Yanagisawa, Kouichi Inukai, Mitsuhiko Noda, Akira Shimada
BACKGROUND: Sodium-glucose cotransporter 2 (SGLT2) inhibitors are novel agents used to treat type 2 diabetic patients. We investigated the efficacy of the SGLT2 inhibitor ipragliflozin on diabetic nephropathy in Japanese patients with type 2 diabetes. METHODS: A 50 mg dose of ipragliflozin was administered for 24 weeks to 50 patients with type 2 diabetes who were concomitantly managed with diet and exercise therapy alone or antidiabetic medications other than SGLT2 inhibitors...
February 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28075066/efficacy-and-safety-of-fixed-dose-combination-therapy-alogliptin-plus-metformin-in-asian-patients-with-type-2-diabetes-a-phase-3-trial
#6
Linong Ji, Ling Li, Jian Kuang, Tao Yang, Dong-Jun Kim, Azidah Abdul Kadir, Chien-Ning Huang, Douglas Lee
This study evaluated the efficacy and safety of 26 weeks of twice-daily (BID) alogliptin + metformin fixed-dose combination (FDC) therapy in Asian patients with type 2 diabetes. Patients aged 18 - 75 years with hemoglobin A1c (HbA1c) 7.5 - 10.0% after ≥2 months of diet and exercise and a 4-week placebo run-in were enrolled. Eligible patients were randomized (1:1:1:1) to placebo, alogliptin 12.5 mg BID, metformin 500 mg BID, or alogliptin 12.5 mg plus metformin 500 mg FDC BID. The primary endpoint was change in HbA1c from baseline to end of treatment (Week 26)...
January 11, 2017: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/28074747/liraglutide-a-glucagon-like-peptide-1-agonist-for-chronic-weight-management
#7
Kendra R Manigault, Maria Miller Thurston
OBJECTIVE: To review the efficacy and safety of liraglutide 3.0 mg for weight loss. DATA SOURCE: A literature search was performed using PubMed and MEDLINE from 2000 to 2016. The following key terms were used alone or in combination: glucagon-like peptide-1 agonist, liraglutide, obesity, overweight, and weight loss. Additional supporting literature was identified utilizing the reference lists of the preceding articles. STUDY SELECTION: Analyzed studies were published in English and investigated use of liraglutide and its impact on weight loss...
December 1, 2016: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28071959/tenfold-risk-increase-of-major-cardiovascular-events-after-high-limb-amputation-with-non-compliance-for-secondary-prevention-measures
#8
Evgeniya V Shalaeva, Hugo Saner, Bakhtiyor B Janabaev, Aleksandra V Shalaeva
Background The aim of the study was to evaluate the impact of compliance with lifestyle recommendations and medication on 1-year prevention of major adverse cardiovascular events (MACE) in patients with type 2 diabetes (T2D) after trans-femoral amputation (TFA). Methods In this prospective single-center interventional cohort study, 179 consecutive T2D patients with symptomatic coronary artery disease (CAD) underwent 1-year follow-up examination after TFA in 2013. Lower limb and coronary artery CT angiography were provided before surgery; physical examination and laboratory tests were performed at baseline and every month after TFA for 1 year...
January 1, 2017: European Journal of Preventive Cardiology
https://www.readbyqxmd.com/read/28067740/update-on-management-of-type-1-diabetes-and-type-2-diabetes-in-athletes
#9
Jane E Yardley, Sheri R Colberg
Optimal blood glucose management still remains the biggest challenge in active individuals with diabetes, particularly in insulin users, but some newer strategies have been introduced to maintain blood glucose control. Recent studies emphasize the importance of exercise intensity on glycemic balance. In individuals with type 1 and type 2 diabetes, both resistance and high-intensity intermittent exercise have been shown to confer beneficial physiological adaptations in training studies, while also showing acute glycemic benefits from single sessions...
January 2017: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/28063503/does-oral-glutamine-improve-insulin-sensitivity-in-adolescents-with-type-1-diabetes
#10
Lournaris Torres-Santiago, Nelly Mauras, Jobayer Hossain, Arthur L Weltman, Dominique Darmaun
OBJECTIVE: The decline in insulin sensitivity (SI) associated with puberty increases the difficulty of achieving glycemic control in adolescents with type 1 diabetes (T1D). The aim of this study was to determine whether glutamine supplementation affects blood glucose by enhancing SI in adolescents with T1D. METHODS: Thirteen adolescents with T1D (HbA1C 8.2 ± 0.1%) were admitted to perform afternoon exercise (four 15-min treadmill/5-min rest cycles of exercise) on two occasions within a 4-wk period...
February 2017: Nutrition
https://www.readbyqxmd.com/read/28060528/-learning-can-improve-the-blood-glucose-control-performance-for-type-1-diabetes-mellitus
#11
Youqing Wang, Jinping Zhang, Fanmao Zeng, Na Wang, Xiaoping Chen, Bo Zhang, Dong Zhao, Wenying Yang, Claudio Cobelli
BACKGROUND: A learning-type artificial pancreas has been proposed to exploit the repetitive nature in the blood glucose dynamics. We clinically evaluated the efficacy of the learning-type artificial pancreas. METHODS: We conducted a pilot clinical study in 10 participants of mean age 36.1 years (standard deviation [SD] 12.7; range 16-58) with type 1 diabetes. Each trial was conducted for eight consecutive mornings. The first two mornings were open-loop to obtain the individualized parameters...
January 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28029178/exercise-during-pregnancy-and-risk-of-preterm-birth-in-overweight-and-obese-women-a-systematic-review-and-meta-analysis-of-randomized-controlled-trials
#12
Elena Rita Magro-Malosso, Gabriele Saccone, Daniele Di Mascio, Mariarosaria Di Tommaso, Vincenzo Berghella
INTRODUCTION: The incidence of overweight and obesity in pregnancy has risen significantly in the last decades. Overweight and obesity have been shown to increase the risk for some adverse obstetric outcome. Lifestyle interventions, such as diet, physical activity and behavior changes, may reduce these risks promoting weight loss and/or preventing excessive weight gain. The possible impact of exercise on the risk of preterm birth (PTB) in overweight or obese women is controversial. Therefore, the aim of our study was to evaluate the effect of exercise on the risk of PTB in overweight or obese pregnant women...
December 28, 2016: Acta Obstetricia et Gynecologica Scandinavica
https://www.readbyqxmd.com/read/28024987/effects-of-high-intensity-training-on-cardiovascular-risk-factors-in-pre-and-postmenopausal-women
#13
Camilla M Mandrup, Jon Egelund, Michael Nyberg, Martina H Lundberg Slingsby, Caroline Andersen, Sofie Løgstrup, Jens Bangsbo, Charlotte Suetta, Bente Stallknecht, Ylva Hellsten
BACKGROUND: Menopause is associated with increased risk of cardiovascular disease and the causal factors have been proposed to be the loss of estrogen and the subsequent alterations of the hormonal milieu. However, which factors that contribute to the deterioration of cardio-metabolic health in postmenopausal women is debated as the menopausal transition is also associated with increased age and fat mass. Furthermore, indications of reduced cardio-metabolic adaptations to exercise in postmenopausal women add to the adverse health profile...
December 23, 2016: American Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28013340/frequent-and-intensive-physical-activity-reduces-risk-of-cardiovascular-events-in-type-1-diabetes
#14
Heidi Tikkanen-Dolenc, Johan Wadén, Carol Forsblom, Valma Harjutsalo, Lena M Thorn, Markku Saraheimo, Nina Elonen, Milla Rosengård-Bärlund, Daniel Gordin, Heikki O Tikkanen, Per-Henrik Groop
AIMS/HYPOTHESIS: Cardiovascular disease (CVD) is the most common cause of premature death and disability among patients with type 1 diabetes. Diabetic nephropathy accounts for the increased cardiovascular morbidity and mortality of these patients. We recently showed that the intensity of exercise predicts the incidence and progression of diabetic nephropathy in patients with type 1 diabetes. Little is known about the relationship between physical activity and CVD. Therefore, we studied how physical activity affects the risk of CVD events in patients with type 1 diabetes...
December 24, 2016: Diabetologia
https://www.readbyqxmd.com/read/28006437/does-exercise-pose-a-challenge-to-glucoregulation-after-clinical-islet-transplantation
#15
Deanna R Funk, Normand G Boulé, Peter A Senior, Jane E Yardley
Islet transplantation (ITx) is effective in preventing severe hypoglycemia by restoring glucose-dependent insulin secretion in type 1 diabetes (T1D), but may not normalize glucose regulation. Studies suggest that physical activity plays a role in maintaining β-cell mass and function in individuals with type 2 diabetes and animal models of diabetes. This could indicate that physical activity plays a role in graft survival in ITx recipients. This review's objective is to assess current knowledge related to physical activity in ITx recipients...
January 2017: Applied Physiology, Nutrition, and Metabolism, Physiologie Appliquée, Nutrition et Métabolisme
https://www.readbyqxmd.com/read/27996320/mitigating-reductions-in-glucose-during-exercise-on-closed-loop-insulin-delivery-the-ex-snacks-study
#16
Neha S Patel, Michelle A Van Name, Eda Cengiz, Lori R Carria, Eileen M Tichy, Kate Weyman, Stuart A Weinzimer, William V Tamborlane, Jennifer L Sherr
OBJECTIVE: To assess whether snacking could be used with closed-loop (CL) insulin delivery to avoid exercise-induced reductions in plasma glucose (PG), as well as elevations in PG at the end of exercise. RESEARCH DESIGN AND METHODS: Twelve type 1 diabetes (T1D) subjects (age 13-36 years, duration 10.7 ± 8.4 years, A1c 7.4% ± 0.8% [57 ± 8.7 mmol/mol]) underwent two 105-min exercise studies while under CL control: CL alone and CL+snack. Exercise, commenced at 3 PM, consisted of four 15-min periods of brisk treadmill walking to 65%-70% HRmax (separated by three 5-min rest periods), followed by a 30-min recovery period...
December 2016: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/27989545/physical-activity-and-sedentary-behavior-levels-in-children-and-adolescents-with-type-1-diabetes-using-insulin-pump-or-injection-therapy-the-importance-of-parental-activity-profile
#17
Isabelle Michaud, Mélanie Henderson, Laurent Legault, Marie-Eve Mathieu
In children and adolescents, treatments for type 1 diabetes (T1D) have recently evolved with the introduction of the insulin pump. However, little is known about how a pump is associated with physical activity (PA) patterns. The goal of the study was to examine the activity profile of Canadian children and adolescents with T1D according to their insulin treatment (pump vs. injections), as well as barriers to exercise and parental lifestyle habits. A self-administered questionnaire was completed by 188 subjects with T1D aged 6 to 17 and their parents at the endocrinology clinic of Sainte-Justine's University Hospital Center (Montreal, Canada)...
December 8, 2016: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/27984020/physical-exercise-reverses-spatial-memory-deficit-and-induces-hippocampal-astrocyte-plasticity-in-diabetic-rats
#18
Priscylla Nunes de Senna, Pamela Brambilla Bagatini, Fabiana Galland, Larissa Bobermin, Patrícia Severo do Nascimento, Patrícia Nardin, Ana Carolina Tramontina, Carlos Alberto Gonçalves, Matilde Achaval, Léder Leal Xavier
Physical exercise can induce brain plasticity and reduce the cognitive decline observed in type 1 diabetes mellitus (T1DM). We investigated the effects of physical exercise to prevent or reverse spatial memory deficits produced by diabetes and some biochemical and immunohistochemical changes in hippocampal astrocytes of T1DM model. In this study, 56 male Wistar rats were divided in four groups: trained control (TC), non-trained control (NTC), trained diabetic (TD) and non-trained diabetic (NTD). 27 days after streptozotocin-induced (STZ) diabetes, the exercise groups were submitted to 5 weeks of aerobic exercise...
January 15, 2017: Brain Research
https://www.readbyqxmd.com/read/27983910/active-subjects-with-autoimmune-type-1-diabetes-have-better-metabolic-profiles-than-sedentary-controls
#19
M Adamo, R Codella, F Casiraghi, A Ferrulli, C Macrì, E Bazzigaluppi, I Terruzzi, L Inverardi, C Ricordi, L Luzi
<p>Previous studies in humans with type 1 diabetes (T1D) and in non-obese diabetic mice have investigated the beneficial immunomodulatory potential of aerobic physical activity. Performing high volume of aerobic exercise may favorably regulate autoimmunity in diabetes. We tested whether increased physical activity is a self-sufficient positive factor in T1D subjects.</p><p>During a 3-month observational period, active (6M; 40.5±6.1 years; BMI 24.5±2.1) and sedentary (4M, 3F; 35.9±8.9 years; BMI 25...
20, 2016: Cell Transplantation
https://www.readbyqxmd.com/read/27941056/a-non-exercise-method-to-determine-cardiorespiratory-fitness-identifies-females-predicted-to-be-at-high-risk-of-type-2-diabetes
#20
Benjamin J Gray, Jeffrey W Stephens, Daniel Turner, Michael Thomas, Sally P Williams, Kerry Morgan, Meurig Williams, Sam Rice, Richard M Bracken
This study examined the relationship between cardiorespiratory fitness determined by a non-exercise testing method for estimating fitness and predicted risk of developing type 2 diabetes mellitus using five risk assessments/questionnaires (Leicester Diabetes Risk Score, QDiabetes, Cambridge Risk Score, Finnish Diabetes Risk Score and American Diabetes Association Diabetes Risk Test). Retrospective analysis was performed on 330 female individuals with no prior diagnosis of cardiovascular disease or type 2 diabetes mellitus who participated in the Prosiect Sir Gâr workplace initiative in Carmarthenshire, South Wales...
January 2017: Diabetes & Vascular Disease Research
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