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Exercise, type-1 diabetes

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https://www.readbyqxmd.com/read/28821576/effect-of-a-behavioral-intervention-strategy-for-adoption-and-maintenance-of-a-physically-active-lifestyle-the-italian-diabetes-and-exercise-study-ides-2-a-randomized-controlled-trial
#1
Stefano Balducci, Valeria D'Errico, Jonida Haxhi, Massimo Sacchetti, Giorgio Orlando, Patrizia Cardelli, Martina Vitale, Lucilla Bollanti, Francesco Conti, Silvano Zanuso, Antonio Nicolucci, Giuseppe Pugliese
OBJECTIVE: Adherence to physical activity (PA) recommendations is hampered by the lack of effective strategies to promote behavior change. The Italian Diabetes and Exercise Study_2 is a randomized controlled trial evaluating a novel behavioral intervention strategy for increasing PA and decreasing sedentary time (SED-time) in patients with type 2 diabetes. RESEARCH DESIGN AND METHODS: The study randomized 300 physically inactive and sedentary patients with type 2 diabetes 1:1 to receive theoretical and practical counseling once yearly for 3 years (intervention group [INT]) or standard care (control group [CON])...
August 18, 2017: Diabetes Care
https://www.readbyqxmd.com/read/28816922/nil-whey-protein-effect-on-glycaemic-control-after-intense-mixed-mode-training-in-t2d
#2
Kim A Gaffney, Adam Lucero, Lee Stoner, James Faulkner, Patricia Whitfield, Jeremy Krebs, David S Rowlands
While intense endurance and resistance exercise training and whey protein supplementation have both been shown to independently improve glycaemic control, no known studies have examined the effect of high-intensity mixed-mode interval training (MMIT) and whey supplementation in adults with Type-2 diabetes (T2D). PURPOSE: To determine if peri-training whey protein supplementation combined with MMIT can improve glycaemic control. METHODS: In a double-blind randomised controlled trial, 24 men (55...
August 14, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28812204/multivariable-adaptive-artificial-pancreas-system-in-type-1-diabetes
#3
REVIEW
Ali Cinar
PURPOSE OF REVIEW: The review summarizes the current state of the artificial pancreas (AP) systems and introduces various new modules that should be included in future AP systems. RECENT FINDINGS: A fully automated AP must be able to detect and mitigate the effects of meals, exercise, stress and sleep on blood glucose concentrations. This can only be achieved by using a multivariable approach that leverages information from wearable devices that provide real-time streaming data about various physiological variables that indicate imminent changes in blood glucose concentrations caused by meals, exercise, stress and sleep...
August 15, 2017: Current Diabetes Reports
https://www.readbyqxmd.com/read/28811858/effectiveness-of-ipragliflozin-for-reducing-hemoglobin-a1c-in-patients-with-a-shorter-type-2-diabetes-duration-interim-report-of-the-assign-k-study
#4
Kotaro Iemitsu, Takehiro Kawata, Takashi Iizuka, Masahiro Takihata, Masahiko Takai, Shigeru Nakajima, Nobuaki Minami, Shinichi Umezawa, Akira Kanamori, Hiroshi Takeda, Shogo Ito, Taisuke Kikuchi, Hikaru Amemiya, Mizuki Kaneshiro, Atsuko Mokubo, Tetsuo Takuma, Hideo Machimura, Keiji Tanaka, Taro Asakura, Akira Kubota, Sachio Aoyanagi, Kazuhiko Hoshino, Masashi Ishikawa, Yoko Matsuzawa, Mitsuo Obana, Nobuo Sasai, Hideaki Kaneshige, Fuyuki Minagawa, Tatsuya Saito, Kazuaki Shinoda, Masaaki Miyakawa, Yasushi Tanaka, Yasuo Terauchi, Ikuro Matsuba
BACKGROUND: Ipragliflozin is a selective sodium glucose co-transporter 2 inhibitor. The ASSIGN-K study is investigating the efficacy and safety of ipragliflozin for type 2 diabetes mellitus (T2DM) in the real-world clinical setting. METHODS: Japanese T2DM patients with inadequate glycemic control despite diet and exercise with/without pharmacotherapy were enrolled in an investigator-driven, multicenter, prospective, observational study examining the efficacy and safety of ipragliflozin treatment (50 mg/day for 52 weeks)...
September 2017: Journal of Clinical Medicine Research
https://www.readbyqxmd.com/read/28811774/effects-of-supervised-structured-aerobic-exercise-training-program-on-fasting-blood-glucose-level-plasma-insulin-level-glycemic-control-and-insulin-resistance-in-type-2-diabetes-mellitus
#5
Syed Shakil-Ur-Rehman, Hossein Karimi, Syed Amir Gillani
OBJECTIVE: To determine the effects of supervised structured aerobic exercise training (SSAET) program on fasting blood glucose level (FBGL), plasma insulin level (PIL), glycemic control (GC), and insulin resistance (IR) in type 2 diabetes mellitus (T2DM). METHODS: Riphah Rehabilitation and Research Centre (RRRC) was the clinical setting for this randomized controlled trial, located at Pakistan Railways General Hospital (PRGH), Rawalpindi, Pakistan. Study duration was 18 months from January 1, 2015 to June 30, 2016...
May 2017: Pakistan Journal of Medical Sciences Quarterly
https://www.readbyqxmd.com/read/28807404/prognostic-usefulness-of-cardiac-stress-test-modalities-in-patients-with-type-2-diabetes-mellitus-who-underwent-myocardial-perfusion-scintigraphy-from-the-basel-asymptomatic-high-risk-diabetics-outcome-trial
#6
Federico Caobelli, Philip Haaf, Joannis Chronis, Gianluca Haenny, Miriam Brinkert, Matthias E Pfisterer, Michael J Zellweger
Our study aimed to assess predictors of the stress test technique used and to evaluate the impact of exercise level achieved on risk stratification in patients with asymptomatic type 2 diabetes without a previous coronary artery disease. Little is known whether co-morbidities of these patients predict the stress technique and whether physical performance provides risk stratification: 400 patients underwent clinical evaluation and myocardial perfusion scintigraphy (MPS) using physical or pharmacological stress...
July 20, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28805967/prognostic-value-of-exercise-capacity-among-men-undergoing-pharmacologic-treatment-for-erectile-dysfunction-the-fit-project
#7
Robert V Same, Mahmoud Al Rifai, David I Feldman, Kevin L Billups, Clinton A Brawner, Zeina A Dardari, Jonathan K Ehrman, Steven J Keteyian, Mouaz H Al-Mallah, Michael J Blaha
BACKGROUND: Vascular erectile dysfunction (ED) has been identified as a potentially useful risk factor for predicting future cardiovascular events, particularly in younger men. Because these men typically score more favorably on traditional cardiovascular disease risk assessment tools, there exists a gap in knowledge for how to most appropriately identify those men who would benefit from more aggressive treatments. To date, no studies have examined the impact of fitness on cardiovascular outcomes in men with ED...
August 14, 2017: Clinical Cardiology
https://www.readbyqxmd.com/read/28797359/primary-prevention-of-cardiovascular%C3%A2-disease-in-diabetes-mellitus
#8
REVIEW
Jonathan D Newman, Arthur Z Schwartzbard, Howard S Weintraub, Ira J Goldberg, Jeffrey S Berger
Type 2 diabetes mellitus (T2D) is a major risk factor for cardiovascular disease (CVD), the most common cause of death in T2D. Yet, <50% of U.S. adults with T2D meet recommended guidelines for CVD prevention. The burden of T2D is increasing: by 2050, approximately 1 in 3 U.S. individuals may have T2D, and patients with T2D will comprise an increasingly large proportion of the CVD population. The authors believe it is imperative that we expand the use of therapies proven to reduce CVD risk in patients with T2D...
August 15, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28795013/management-of-diabetes-mellitus-in-children-and-adolescents-engaging-in-physical-activity
#9
REVIEW
Silpa Nadella, Justin A Indyk, Manmohan K Kamboj
Regular physical activity is an important component in the management of both type 1 and type 2 diabetes mellitus (T1DM and T2DM), as it has the potential to improve glycemic control, delay cardiovascular complications, and increase overall well-being. Unfortunately, many children and adolescents with diabetes do not partake in regular exercise and physical activity for multiple reasons. This review identifies the barriers to participation from the aspect of the patient, caregiver, and the healthcare provider...
July 2017: Translational pediatrics
https://www.readbyqxmd.com/read/28793919/prevention-of-diabetes-in-overweight-obese-children-through-a-family-based-intervention-program-including-supervised-exercise-predikid-project-study-protocol-for-a-randomized-controlled-trial
#10
Lide Arenaza, María Medrano, María Amasene, Beatriz Rodríguez-Vigil, Ignacio Díez, Manuel Graña, Ignacio Tobalina, Edurne Maiz, Edurne Arteche, Eider Larrarte, Inge Huybrechts, Catherine L Davis, Jonatan R Ruiz, Francisco B Ortega, Javier Margareto, Idoia Labayen
BACKGROUND: The global pandemic of obesity has led to an increased risk for prediabetes and type-2 diabetes (T2D). The aims of the current project are: (1) to evaluate the effect of a 22-week family based intervention program, including supervised exercise, on insulin resistance syndrome (IRS) risk in children with a high risk of developing T2D and (2) to identify the profile of microRNA in circulating exosomes and in peripheral blood mononuclear cells in children with a high risk of developing T2D and its response to a multidisciplinary intervention program including exercise...
August 10, 2017: Trials
https://www.readbyqxmd.com/read/28792627/physical-activity-and-type-1-diabetes-an-underused-therapy
#11
T Yates, M J Davies
Aerobic exercise training has consistently been shown to be an effective therapy in the management of Type 2 diabetes, resulting in reductions in HbA1c of ~8 mmol/mol (0.7%) [1]. Moreover, physical activity and cardiorespiratory fitness have been strongly associated with a decreased risk of morbidity and mortality in those with Type 2 diabetes. Despite a wealth of evidence for Type 2 diabetes, less is understood about the therapeutic potential of physical activity in Type 1 diabetes. This article is protected by copyright...
August 9, 2017: Diabetic Medicine: a Journal of the British Diabetic Association
https://www.readbyqxmd.com/read/28790929/combined-interval-training-and-post-exercise-nutrition-in-type-2-diabetes-a-randomized-control-trial
#12
Monique E Francois, Cody Durrer, Kevin J Pistawka, Frank A Halperin, Courtney Chang, Jonathan P Little
Background: High-intensity interval training (HIIT) can improve several aspects of cardiometabolic health. Previous studies have suggested that adaptations to exercise training can be augmented with post-exercise milk or protein consumption, but whether this nutritional strategy can impact the cardiometabolic adaptations to HIIT in type 2 diabetes is unknown. Objective: To determine if the addition of a post-exercise milk or protein beverage to a high-intensity interval training (HIIT) intervention improves cardiometabolic health in individuals with type 2 diabetes...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28782491/the-impact-of-cardiovascular-diseases-on-the-cardiovascular-regulation-during-exercise-in-humans-studies-on-the-metaboreflex-elicited-by-the-post-exercise-muscle-ischemia-method
#13
Antonio Crisafulli
Hemodynamics during dynamic exercise is finely regulated by some neural mechanisms. One of these mechanisms is the metabolic part of the exercise pressor reflex, i.e. the muscle metaboreflex. Hemodynamic response during the metaboreflex is characterised by the recruitment of the reserves in cardiac inotropism, pre-load, after-load and chronotropism. If one of these reserves is exhausted, then the cardiovascular response is achieved by recruiting one of the other reserves, thereby indicating a remarkable plasticity of the control of circulation...
August 4, 2017: Current Cardiology Reviews
https://www.readbyqxmd.com/read/28772017/an-initiative-to-improve-primary-prevention-of-cardiovascular-disease-in-adults-with-type-ii-diabetes-based-on-the-acc-aha-2013-and-ada-2016-guidelines
#14
Litzie Garza, Jean Dols, Maria Gillespie
PURPOSE: This project was designed to increase family practice clinicians' adherence to the American College of Cardiology/American Heart Association (2013) and American Diabetes Association (ADA, 2016) clinical practice guidelines for the prevention of cardiovascular disease (CVD) in 40- to 75-year-old adults with type II diabetes (DMII) through interactive education, an electronic alert, and quality improvement sessions on the treatment and management of cholesterol in a family practice primary care setting...
August 3, 2017: Journal of the American Association of Nurse Practitioners
https://www.readbyqxmd.com/read/28767602/iatrogenic-rupture-of-the-left-main-bronchus-secondary-to-repeated-surgical-lobe-torsion-during-double-lumen-tube-placement-a-case-report
#15
Zong Ming Jiang, Chu Zhang, Zhong Hua Chen
RATIONALE: Bronchial rupture is a rare but potentially life-threatening complication during double-lumen endobronchial tube placement. The rupture of the left main bronchus resulting from repeated surgical torsion is uncommon. PATIENT CONCERNS: A 70-year-old man with a history of chronic obstructive pulmonary disease (COPD), intermediate emphysema, chronic bronchitis, hypertension, type 2 diabetes mellitus, and L3-L4 lumbar intervertebral disc herniation. Chest x-ray and computed tomography revealed a solitary pulmonary nodule in the left lower lobe...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28767276/closed-loop-control-without-meal-announcement-in-type-1-diabetes
#16
Faye M Cameron, Trang T Ly, Bruce A Buckingham, David M Maahs, Gregory P Forlenza, Carol J Levy, David Lam, Paula Clinton, Laurel H Messer, Emily Westfall, Camilla Levister, Yan Yan Xie, Nihat Baysal, Daniel Howsmon, Stephen D Patek, B Wayne Bequette
OBJECTIVE: A fully closed-loop insulin-only system was developed to provide glucose control in patients with type 1 diabetes without requiring announcement of meals or activity. Our goal was to assess initial safety and efficacy of this system. RESEARCH DESIGN AND METHODS: The multiple model probabilistic controller (MMPPC) anticipates meals when the patient is awake. The controller used the subject's basal rates and total daily insulin dose for initialization. The system was tested at two sites on 10 patients in a 30-h inpatient study, followed by 15 subjects at three sites in a 54-h supervised hotel study, where the controller was challenged by exercise and unannounced meals...
August 2, 2017: Diabetes Technology & Therapeutics
https://www.readbyqxmd.com/read/28760008/using-an-expert-panel-to-develop-social-support-program-sequencing-for-young-adults-with-type-1-diabetes
#17
Patrick J Brady, Hee-Jung Song, James Butler
BACKGROUND: Young adults living with type 1 diabetes (T1DM) often encounter poor health outcomes, such as uncontrolled blood glucose levels. Social support programs can be a helpful method to support T1DM self-management. Effectively planning and tailoring social support programs for young adults living with T1DM are crucial for improving these programs and associated outcomes. OBJECTIVES: This study convened an expert panel primarily composed of young adults living with T1DM to generate ideas and key components for sequential inclusion in social support programs prioritizing them...
July 1, 2017: Health Promotion Practice
https://www.readbyqxmd.com/read/28750957/effects-of-aerobic-exercise-on-functional-capacity-anthropometric-measurements-and-inflammatory-markers-in-diabetic-elderly-women
#18
Daniela Maria da Cruz Dos Anjos, Bruno de Souza Moreira, Renata Noce Kirkwood, Rosângela Corrêa Dias, Daniele Sirineu Pereira, Leani Souza Máximo Pereira
This study investigated the effects of an aerobic training program on functional capacity [Timed Up and Go test (TUG), timed 10-m walk test (10MWT), five-repetition sit-to-stand test (5-STS), handgrip strength test (HGS) and one-legged stance test (OLS)], anthropometric measurements [body mass, body mass index (BMI), waist and hip circumferences and waist-to-hip ratio] and plasma levels of inflammatory markers [soluble tumor necrosis factor receptors 1 and 2, and interleukins 6 and 10] in 43 elderly women with type 2 diabetes mellitus...
July 2017: Journal of Bodywork and Movement Therapies
https://www.readbyqxmd.com/read/28750433/effect-of-a-12-week-aerobic-exercise-training-on-serum-fetuin-a-and-adipocytokine-levels-in-type-2-diabetes
#19
Ling-Yun Zhang, Tao Liu, Ya-Qin Teng, Xiao-Yan Yao, Tian-Tian Zhao, Liang-Yan Lin, Qing-Song Jin, Yong-Jun Jin
Objective We aimed to evaluate the effect of 12-week aerobic exercise training on fetuin-A levels in type 2 diabetes mellitus and examine the relationships between fetuin-A and adipocytokine levels and cardiovascular risk factors. Methods The study included 32 patients with type 2 diabetes mellitus who were assigned to an exercise or a control group. The exercise group underwent 12 weeks of exercise (consisting of a 5-min warm-up, 60-min aerobic bicycle training performed at 70% of the maximal heart rate, a cool-down period, 5 times/week)...
July 27, 2017: Experimental and Clinical Endocrinology & Diabetes
https://www.readbyqxmd.com/read/28744255/glycemic-and-metabolic-effects-of-two-long-bouts-of-moderate-intensity-exercise-in-men-with-normal-glucose-tolerance-or-type-2-diabetes
#20
Saeed Reza Eshghi, Kevin Fletcher, Étienne Myette-Côté, Cody Durrer, Raniah Q Gabr, Jonathan P Little, Peter Senior, Craig Steinback, Margie H Davenport, Gordon J Bell, Dion R Brocks, Normand G Boulé
BACKGROUND: The glycemic and insulinemic responses following 30-60 min of exercise have been extensively studied, and a dose-response has been proposed between exercise duration, or volume, and improvements in glucose tolerance or insulin sensitivity. However, few studies have examined the effects of longer bouts of exercise in type 2 diabetes (T2D). Longer bouts may have a greater potential to affect glucagon, interleukin-6 (IL-6) and incretin hormones [i.e., glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic peptide (GIP)]...
2017: Frontiers in Endocrinology
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