keyword
https://read.qxmd.com/read/38544313/risk-factors-associated-with-fluconazole-resistance-in-candida-parapsilosis-candidemia-a-case-case-study
#1
JOURNAL ARTICLE
Sabri Atalay, Derya Çağlayan, Eren Arkalı, Ufuk Sönmez, Pınar Şamlıoğlu
BACKGROUND: Candida species are among the most important invasive pathogens in intensive care units (ICUs). Non-albicans species including Candida parapsilosis (C. parapsilosis) has increased in recent years. Fluconazole is the leading antifungal agent but resistance is a concern among C. parapsilosis species. OBJECTIVES: The aim of this study was to determine the factors associated with fluconazole resistance in patients with candidemia due to C. parapsilosis in ICUs...
March 2024: Mycoses
https://read.qxmd.com/read/38535242/correction-jim%C3%A3-nez-ortigosa-et-al-cryo-electron-tomography-of-candida-glabrata-plasma-membrane-proteins-j-fungi-2021-7-120
#2
Cristina Jiménez-Ortigosa, Jennifer Jiang, Muyuan Chen, Xuyuan Kuang, Kelley R Healey, Paul Castellano, Nikpreet Boparai, Steven J Ludtke, David S Perlin, Wei Dai
The authors wish to update the article title to "Cryo-Electron Tomography of Candida glabrata Plasma Membrane Proteins" [...].
March 6, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535241/genetic-diversity-and-reproduction-trends-of-phytophthora-infestans-in-estonia-eu_41_a2-detected-without-an-indication-of-clonal-reproduction
#3
JOURNAL ARTICLE
Britt Puidet, Mati Koppel, Riinu Kiiker
This study explores the population dynamics of Phytophthora infestans in Estonia from 2005 to 2022, focusing on genetic diversity and potential shifts in reproductive strategies. In total, 153 P. infestans isolates were collected throughout Estonia over ten growing seasons. Genotyping revealed considerable genetic diversity, with most isolates not corresponding to known multilocus genotypes (MLGs). Still, instances of invasive clonal lineages were observed, notably EU_41_A2. The data indicate the likelihood of random mating rather than clonal reproduction in all the analyzed years...
March 21, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535240/reply-to-navarro-fernandez-i-nailing-down-clinical-nuances-comment-on-crotti-et-al-a-terbinafine-sensitive-trichophyton-indotineae-strain-in-italy-the-first-clinical-case-of-tinea-corporis-and-onychomycosis-j-fungi-2023-9-865
#4
JOURNAL ARTICLE
Silvia Crotti, Deborah Cruciani, Manuela Papini
We have read with interest the comments and observations made regarding the paper "A terbinafine sensitive Trichophyton indotineae strain in Italy: the first clinical case of tinea corporis and onychomycosis" [...].
March 21, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535239/nailing-down-clinical-nuances-comment-on-crotti-et-al-a-terbinafine-sensitive-trichophyton-indotineae-strain-in-italy-the-first-clinical-case-of-tinea-corporis-and-onychomycosis-j-fungi-2023-9-865
#5
JOURNAL ARTICLE
Inigo Navarro-Fernandez
I have read the paper "A Terbinafine Sensitive Trichophyton indotineae Strain in Italy: The First Clinical Case of tinea corporis and onychomycosis" by Crotti et al [...].
March 21, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535238/-pestalotiopsis-jiangsuensis-sp-nov-causing-needle-blight-on-pinus-massoniana-in-china
#6
JOURNAL ARTICLE
Hui Li, Bing-Yao Peng, Jun-Ya Xie, Yu-Qing Bai, De-Wei Li, Li-Hua Zhu
Pinus massoniana Lamb. is an important, common afforestation and timber tree species in China. Species of Pestalotiopsis are well-known pathogens of needle blight. In this study, the five representative strains were isolated from needle blight from needles of Pi. massoniana in Nanjing, Jiangsu, China. Based on multi-locus phylogenetic analyses of the three genomic loci (ITS, TEF1 , and TUB2 ), in conjunction with morphological characteristics, a new species, namely Pestalotiopsis jiangsuensis sp. nov., was described and reported...
March 21, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535237/the-function-of-different-subunits-of-the-molecular-chaperone-cct-in-the-microsporidium-nosema-bombycis-nbcct%C3%AE-interacts-with-nbcct%C3%AE
#7
JOURNAL ARTICLE
Sheng Xu, Ying Chen, Jingru Qi, Runpeng Wang, Erjun Wei, Qiang Wang, Yiling Zhang, Xudong Tang, Zhongyuan Shen
Chaperonin containing tailless complex polypeptide 1 (CCT) is a molecular chaperone protein that consists of eight completely different subunits and assists in the folding of newly synthesized peptides. The zeta subunit of CCT is a regulatory factor for the folding and assembly of cytoskeletal proteins as individuals or complexes. In this study, the zeta subunit of Nosema bombycis (NbCCTζ) is identified for the first time. The complete ORF of the NbCCTζ gene is 1533 bp in length and encodes a 510 amino acid polypeptide...
March 20, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535236/a-comprehensive-assessment-of-ultraviolet-radiation-induced-mutations-in-flammulina-filiformis-using-whole-genome-resequencing
#8
JOURNAL ARTICLE
Qianhui Huang, Xing Han, Zongjun Tong, Youjin Deng, Luyu Xie, Shengrong Liu, Baogui Xie, Weirui Zhang
Nucleotide substitutions have played an important role in molecular evolution, and understanding their dynamics would contribute to genetic studies. Related research with defined DNA sequences lasted for decades until whole-genome sequencing arose. UV radiation (UVR) can generate base changes and other genetic variations in a short period of time, so it would be more meaningful to explore mutations caused by UVR from a genomic perspective. The monokaryon enoki strain WT583 was selected as the experimental material in this study because it can spontaneously produce large amounts of oidia on PDA plates, and the monokaryons originating from oidia have the same genotype as their mother monokaryon...
March 20, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535235/systemic-candida-infection-and-pulmonary-aspergillosis-in-an-alpaca-vicugna-pacos-a-case-report
#9
Andrea Grassi, Claudia Cafarchia, Nicola Decaro, Wafa Rhimi, Vittoriana De Laurentiis, Giulia D'Annunzio, Andrea Luppi, Paola Prati
This study reports a peculiar case of systemic candidiasis infection associated with pulmonary aspergillosis in an apparently immunocompetent alpaca. A captive 7-year-old female alpaca exhibited respiratory symptoms, underwent treatment with benzylpenicillin and dexamethasone, and succumbed to the infection 40 days later. During the post-mortem examination, subcutaneous emphysema, widespread pneumonia with multiple suppurative foci, scattered necro-suppurative lesions throughout the renal and hepatic parenchyma were evident...
March 20, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535234/potential-role-of-sugars-in-the-hyphosphere-of-arbuscular-mycorrhizal-fungi-to-enhance-organic-phosphorus-mobilization
#10
JOURNAL ARTICLE
Zexing Jin, Guiwei Wang, Timothy S George, Lin Zhang
Arbuscular mycorrhizal (AM) fungi engage in symbiosis with more than 80% of terrestrial plants, enlarging root phosphorus (P) absorption volume by producing extensive extraradical hyphae (ERH) in the soil. In addition, AM fungi recruit and cooperate with soil bacteria to enhance soil organic P mobilization and improve fungal and plant fitness through hyphal exudates. However, the role of the dominant compounds in the hyphal exudates in enhancing organic P mobilization in the mycorrhizal pathway is still not well understood...
March 20, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535233/the-effect-of-green-extraction-technologies-on-the-chemical-composition-of-medicinal-chaga-mushroom-extracts
#11
JOURNAL ARTICLE
Vesna Lazić, Anita Klaus, Maja Kozarski, Ana Doroški, Tomislav Tosti, Siniša Simić, Jovana Vunduk
The mushroom industry should implement green extraction technologies; however, there is not enough information on the differences between these techniques expressed as the chemical composition of the resulting extract. In this study, selected types of green extraction techniques (GETs) were used on Chaga ( Inonotus obliquus ) (Fr.) Pilát from Serbia (IS) and Mongolia (IM) to examine the differences that would enable the composition-based technology choices in the mushroom supplement industry. Subcritical water extraction (SWE), microwave-assisted (MW) extraction, and ultrasonic-assisted extraction (VAE) were used to prepare the extracts...
March 19, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535232/-candida-albicans-genes-modulating-echinocandin-susceptibility-of-caspofungin-adapted-mutants-are-constitutively-expressed-in-clinical-isolates-with-intermediate-or-full-resistance-to-echinocandins
#12
JOURNAL ARTICLE
Anshuman Yadav, Sudisht K Sah, David S Perlin, Elena Rustchenko
The opportunistic fungus Candida albicans is the leading cause of invasive candidiasis in immune-compromised individuals. Drugs from the echinocandin (ECN) class, including caspofungin, are used as a first line of therapy against invasive candidiasis. The only known mechanism of clinical resistance to ECNs is point mutations in the FKS1 gene, which encodes the drug target. However, many clinical isolates developed decreased ECN susceptibilities in the absence of resistance-associated FKS1 mutations. We have identified 15 C...
March 19, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535231/new-data-on-boletaceae-agaricomycetes-basidiomycota-from-central-vietnam-with-description-of-two-new-species-and-creation-of-a-new-combination-based-on-morphological-and-phylogenetic-evidence
#13
JOURNAL ARTICLE
Thi Ha Giang Pham, Eugene Popov, Alina Alexandrova, Daria Ivanova, Olga Morozova
Two new species of Boletaceae ( Hortiboletus rubroreticulatus and Tylopilus aurantiovulpinus ) discovered during an investigation of the mycobiota of Central Vietnam (Kon Chu Rang Nature Reserve; Ta Dung National Park; Bidoup-Nui Ba National Park; Kon Ka Kinh National Park) are described on the basis of molecular and morphological data. Illustrated descriptions of their macro- and microscopic features and discussion on similar taxa are given. Additionally, eight species which were recorded for the first time in Vietnam are listed and illustrated here...
March 19, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535230/hsp90-mediated-multi-drug-resistance-in-dna-polymerase-defective-strains-of-candida-albicans
#14
JOURNAL ARTICLE
Bhabasha Gyanadeep Utkalaja, Satya Ranjan Sahu, Sushree Subhashree Parida, Narottam Acharya
The incidence of infections caused by Candida species, specifically by drug-resistant isolates, is a major health concern as they can disseminate to and colonize most vital organs, enhancing morbidity and mortality. Several molecular mechanisms have been reported to be involved in drug resistance. These are mostly drug- and isolate-specific. Here, we characterized three different genetically modified strains of C. albicans that were multi-drug-resistant (MDR) and deciphered a uniform mechanism responsible for resistance...
March 19, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535229/the-oxidative-stress-response-highly-depends-on-glucose-and-iron-availability-in-aspergillus-fumigatus
#15
JOURNAL ARTICLE
Tamás Emri, Károly Antal, Kinga Varga, Barnabás Csaba Gila, István Pócsi
Pathogens have to cope with oxidative, iron- and carbon(glucose)-limitation stresses in the human body. To understand how combined iron-carbon limitation alters oxidative stress responses, Aspergillus fumigatus was cultured in glucose-peptone or peptone containing media supplemented or not with deferiprone as an iron chelator. Changes in the transcriptome in these cultures were recorded after H2 O2 treatment. Responses to oxidative stress were highly dependent on the availability of glucose and iron. Out of the 16 stress responsive antioxidative enzyme genes, only the cat2 catalase-peroxidase gene was upregulated in more than two culturing conditions...
March 18, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535228/five-new-species-of-gymnopilus-from-xizang-autonomous-region-of-china-and-surrounding-areas
#16
JOURNAL ARTICLE
Wen-Qiang Yang, Jia-Xin Li, Mao-Qiang He, Shi-Hui Wang, Xin-Yu Zhu, Dorji Phurbu, Jian-Min Yun, Rui-Lin Zhao
The species of Gymnopilus (Hymenogastraceae, Agricales) are commonly recognized as wood-decaying fungi. Certain members of this genus have been identified as psilocybin-producing mushrooms. Gymnopilus exhibits a diverse range and has a global distribution. In this study, a total of seventy-eight specimens were gathered from ten provinces in China. A comprehensive molecular phylogenetic analysis was conducted, employing gene sequences including ITS, nrLSU, nrSSU, rpb1 , rpb2 , and tef1-α . Additionally, morphological examinations were also carried out...
March 18, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535227/new-vision-of-cell-walls-in-aspergillus-fumigatus-from-solid-state-nmr-spectroscopy
#17
REVIEW
Isha Gautam, Kalpana Singh, Malitha C Dickwella Widanage, Jayasubba Reddy Yarava, Tuo Wang
The fungal cell wall plays a critical role in regulating cellular integrity and communication, and serves as a frontline defense against stress. It is also a prime target for the development of antifungal agents. The cell wall is comprised of diverse polysaccharides and proteins and poses a challenging target for high-resolution structural characterization. Recently, the solid-state nuclear magnetic resonance (ssNMR) analysis of intact Aspergillus fumigatus cells has provided atomic-level insights into the structural polymorphism and functional assembly principles of carbohydrate components within the cell wall...
March 16, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535226/chromogenic-biochemical-and-proteomic-identification-of-yeast-and-yeast-like-microorganisms-isolated-from-clinical-samples-from-animals-of-costa-rica
#18
JOURNAL ARTICLE
Alejandra Calderón-Hernández, Nelly Castro-Bonilla, Mariamalia Cob-Delgado
Yeast infections are challenging human and animal medicine due to low rates of detection and the emergence of unknown ecology isolates. The aim of this study was to verify the biochemical identification of yeasts and yeast-like microorganisms obtained from animals comparing the results with chromogenic media and matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF MS). Between January and August 2023, yeast and yeast-like isolates from samples of animals with suspicion of mycosis were identified using Vitek® 2 Compact, Brilliance® Candida Agar and MALDI Biotyper® MSP...
March 16, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535225/microfungi-associated-with-peach-branch-diseases-in-china
#19
JOURNAL ARTICLE
Ying Zhou, Ishara S Manawasinghe, Zhizheng He, Wei Zhang, Mei Liu, Jinyan Song, Shifang Li, Zaifeng Fan, Jiye Yan
Peach ( Prunus persica L.) is one of the most important and oldest stone fruits grown in China. Even though P. persica is one of the most commonly grown stone fruits in China, little is known about the biodiversity of microfungi associated with peach branch diseases. In the present study, samples were collected from a wide range of peach growing areas in China, and fungal pathogens associated with peach branch diseases were isolated. In total, 85 isolates were obtained and further classified into nine genera and 10 species...
March 15, 2024: Journal of Fungi (Basel, Switzerland)
https://read.qxmd.com/read/38535224/genome-comparisons-between-botrytis-fabae-and-the-closely-related-gray-mold-fungus-botrytis-cinerea-reveal-possible-explanations-for-their-contrasting-host-ranges
#20
JOURNAL ARTICLE
Klaus Klug, Pinkuan Zhu, Patrick Pattar, Tobias Mueller, Nassim Safari, Frederik Sommer, Claudio A Valero-Jiménez, Jan A L van Kan, Bruno Huettel, Kurt Stueber, David Scheuring, Michael Schroda, Matthias Hahn
While Botrytis cinerea causes gray mold on many plants, its close relative, Botrytis fabae , is host-specifically infecting predominantly faba bean plants. To explore the basis for its narrow host range, a gapless genome sequence of B. fabae strain G12 (BfabG12) was generated. The BfabG12 genome encompasses 45.0 Mb, with 16 chromosomal telomere-to-telomere contigs that show high synteny and sequence similarity to the corresponding B. cinerea B05.10 (BcB0510) chromosomes. Compared to BcB0510, it is 6% larger, due to many AT-rich regions containing remnants of transposable elements, but encodes fewer genes (11,420 vs...
March 14, 2024: Journal of Fungi (Basel, Switzerland)
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