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https://www.readbyqxmd.com/read/28749565/melatonin-suppresses-platelet-activation-and-function-against-cardiac-ischemia-reperfusion-injury-via-ppar%C3%AE-fundc1-mitophagy-pathways
#1
Hao Zhou, Dandan Li, Pingjun Zhu, Shunying Hu, Nan Hu, Sai Ma, Ying Zhang, Tianwen Han, Jun Ren, Feng Cao, Yundai Chen
Platelet activation is a major (patho-) physiological mechanism that underlies ischemia/reperfusion (I/R) injury. In this study, we explored the molecular signals for platelet hyperactivity and investigated the beneficial effects of melatonin on platelet reactivity in response to I/R injury. After reperfusion, peroxisome proliferator-activated receptor γ (PPARγ) was progressively downregulated in patients with acute myocardial infarction undergoing coronary artery bypass grafting (CABG) surgery and in mice with I/R injury model...
July 27, 2017: Journal of Pineal Research
https://www.readbyqxmd.com/read/28749039/ventral-onlay-buccal-mucosa-graft-substitution-urethroplasty-for-urethral-stricture-in-females
#2
Bashir M B Mukhtar, Marco Spilotros, Sachin Malde, Tamsin J Greenwell
OBJECTIVE: To present our outcomes of ventral-onlay buccal mucosa graft substitution urethroplasty (VOBMGSU) in treating female urethral stricture (FUS). PATIENTS AND METHODS: A review of a prospectively collected database of 22 consecutive women (median age 50 years, range 34-72) with urethral stricture having VOBMGSU since June 2012 and a minimum follow up of 6 months (median 21.5, range 6-51). Data was analysed for stricture recurrence, change in median peak free flow rate (Qmax) and median post-void residuals (PVR)...
July 27, 2017: BJU International
https://www.readbyqxmd.com/read/28749009/the-origin-of-hierarchical-structure-formation-in-highly-grafted-symmetric-supramolecular-double-comb-diblock-copolymers
#3
Anton H Hofman, Mehedi Reza, Janne Ruokolainen, Gerrit Ten Brinke, Katja Loos
Involving supramolecular chemistry in self-assembling block copolymer systems enables design of complex macromolecular architectures that, in turn, could lead to complex phase behavior. It is an elegant route, as complicated and sensitive synthesis techniques can be avoided. Highly grafted double-comb diblock copolymers based on symmetric double hydrogen bond accepting poly(4-vinylpyridine)-block-poly(N-acryloylpiperidine) diblock copolymers and donating 3-nonadecylphenol amphiphiles are realized and studied systematically by changing the molecular weight of the copolymer...
July 27, 2017: Macromolecular Rapid Communications
https://www.readbyqxmd.com/read/28748863/in-vitro-stent-graft-fenestration-to-preserve-all-supra-aortic-branches-in-the-treatment-of-a-stanford-type-a-aortic-arch-dissection
#4
Tun Wang, Chang Shu, Ming Li, Alan Dardik, Quan-Ming Li
No abstract text is available yet for this article.
August 5, 2017: Chinese Medical Journal
https://www.readbyqxmd.com/read/28748621/outcomes-of-matched-sibling-donor-bone-marrow-transplantation-in-children-using-single-agent-calcineurin-inhibitors-as-prophylaxis-for-graft-versus-host-disease
#5
Caitlin W Elgarten, Danielle E Arnold, Nancy J Bunin, Alix E Seif
BACKGROUND: Optimal graft versus host disease (GVHD) prophylaxis prevents severe manifestations without excess immunosuppression. Standard prophylaxis includes a calcineurin inhibitor (CNI) with low-dose methotrexate. However, single-agent CNI may be sufficient prophylaxis for a defined group of patients. Single-agent CNI has been used for GVHD prophylaxis for human leukocyte antigen (HLA)-matched sibling donor (MSD) bone marrow transplants (BMTs) in young patients at the Children's Hospital of Philadelphia for over 20 years...
July 27, 2017: Pediatric Blood & Cancer
https://www.readbyqxmd.com/read/28748550/porcine-c-peptide-measurement-to-assess-graft-function-in-xenogeneic-porcine-islet-transplantation-editorial-commentary
#6
Henk-Jan Schuurman
No abstract text is available yet for this article.
July 26, 2017: Xenotransplantation
https://www.readbyqxmd.com/read/28748523/management-and-prevention-of-saphenous-vein-graft-failure-a-review
#7
REVIEW
Peter McKavanagh, Bobby Yanagawa, George Zawadowski, Asim Cheema
Coronary artery bypass grafting (CABG) remains a vital treatment for patients with multivessel coronary artery disease (CAD), especially diabetics. The long-term benefit of the internal thoracic artery graft is well established and remains the gold standard for revascularization of severe CAD. It is not always possible to achieve complete revascularization through arterial grafts, necessitating the use of saphenous vein grafts (SVG). Unfortunately, SVGs do not have the same longevity, and their failure is associated with significant adverse cardiac outcomes and mortality...
July 26, 2017: Cardiology and Therapy
https://www.readbyqxmd.com/read/28748521/clinical-outcome-of-alveolar-ridge-augmentation-with-individualized-cad-cam-produced-titanium-mesh
#8
K Sagheb, E Schiegnitz, M Moergel, C Walter, B Al-Nawas, W Wagner
BACKGROUND: The augmentation of the jaw has been and continues to be a sophisticated therapy in implantology. Modern CAD-CAM technologies lead to revival of old and established augmentation techniques such as the use of titanium mesh (TM) for bone augmentation. The aim of this retrospective study was to evaluate the clinical outcome of an individualized CAD-CAM-produced TM based on the CT/DVT-DICOM data of the patients for the first time. METHODS: In 17 patients, 21 different regions were augmented with an individualized CAD-CAM-produced TM (Yxoss CBR®, Filderstadt, Germany)...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28748492/calcium-phosphate-hybridized-tendon-grafts-reduce-femoral-bone-tunnel-enlargement-in-anatomic-single-bundle-acl-reconstruction
#9
Hirotaka Mutsuzaki, Tomonori Kinugasa, Kotaro Ikeda, Masataka Sakane
PURPOSE: This study aimed to clarify the effect of calcium phosphate (CaP)-hybridized tendon grafting versus unhybridized tendon grafting on the morphological changes to the bone tunnels at the aperture 1 year after anatomic single-bundle anterior cruciate ligament (ACL) reconstruction. METHODS: Seventy-three patients were randomized to undergo the CaP (n = 37) or the conventional method (n = 36). All patients underwent computed tomography (CT) evaluation 1 week and 1 year post-operatively...
July 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28748489/hamstring-autograft-maturation-is-superior-to-tibialis-allograft-following-anatomic-single-bundle-anterior-cruciate-ligament-reconstruction
#10
Sang-Gyun Kim, Soo-Hyun Kim, Jae-Gyoon Kim, Ki-Mo Jang, Hong-Chul Lim, Ji-Hoon Bae
PURPOSE: Using second-look arthroscopy, graft maturation was investigated and compared between hamstring (HA) autografts and tibialis anterior (TA) allografts after anatomic single-bundle anterior cruciate ligament reconstruction (ACLR). METHODS: Fifty-six patients who underwent second-look arthroscopy after anatomic single-bundle ACLR with either HA autografts (26, HA group) or TA allografts (30, TA group) from 2007 to 2016 were retrospectively reviewed. Graft maturation on second-look arthroscopy was evaluated in terms of four parameters: graft integrity (tear), synovial coverage, graft tension, and graft vascularization...
July 26, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28748329/impact-of-thiamethoxam-on-honey-bee-queen-apis-mellifera-carnica-reproductive-morphology-and-physiology
#11
Ivana Tlak Gajger, Martina Sakač, Aleš Gregorc
High honey bee losses around the world have been linked in part by the regular use of neonicotinoids in agriculture. In light of the current situation, the aim of this study was to investigate the effects of thiamethoxam on the development of the reproductive system and physiology in the honey bee queen. Two experimental groups of honey bee queen larvae were treated with thiamethoxam during artificial rearing, applied via artificial feed in two cycles. In the first rearing cycle, honey bee larvae received a single treatment dose (4...
July 26, 2017: Bulletin of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28748164/a-thoughtful-use-of-ct-angiography-among-patients-with-prior-coronary-artery-bypass-grafts-more-lights-than-shadows
#12
COMMENT
Umberto Barbero, Mario Iannaccone, Cristina Barbero, Fabrizio D'Ascenzo
No abstract text is available yet for this article.
June 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28748153/prognostic-superiority-of-coronary-artery-bypass-grafting-to-percutaneous-coronary-intervention-in-non-diabetic-patients-with-anatomically-complex-multivessel-coronary-artery-disease
#13
EDITORIAL
Kenji Sakata, Takuya Nakahashi, Masa-Aki Kawashiri
No abstract text is available yet for this article.
June 2017: Cardiovascular Diagnosis and Therapy
https://www.readbyqxmd.com/read/28748046/comparison-of-the-effect-of-three-autogenous-bone-harvesting-methods-on-cell-viability-in-rabbits
#14
Janet Moradi Haghgoo, Seyed Reza Arabi, Seyyed Mohammad Hosseinipanah, Ghasem Solgi, Neda Rastegarfard, Maryam Farhadian
Background. This study was designed to compare the viability of autogenous bone grafts, harvested using different methods, in order to determine the best harvesting technique with respect to more viable cells. Methods. In this animal experimental study, three harvesting methods, including manual instrument (chisel), rotary device and piezosurgery, were used for harvesting bone grafts from the lateral body of the mandible on the left and right sides of 10 rabbits. In each group, 20 bone samples were collected and their viability was assessed using MTS kit...
2017: Journal of Dental Research, Dental Clinics, Dental Prospects
https://www.readbyqxmd.com/read/28747945/the-impact-of-type-2-diabetes-mellitus-on-prognosis-in-patients-with-non-st-elevation-myocardial-infarction
#15
REVIEW
Katarzyna Birkner, Bartosz Hudzik, Mariusz Gąsior
Type 2 diabetes (T2D) is a recognized risk factor for acute coronary syndromes. There is currently no consensus concerning the intensification of antihyperglycemic treatment. According to the available guidelines, it seems that the goal is to achieve glycated hemoglobin (HbA1c) levels below 7% and avoid hypoglycemia. The choice of a revascularization method is influenced by many factors, such as the anatomy of the coronary arteries, severity of atherosclerosis, anatomical location of lesions, and presence of comorbidities...
June 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28747944/impact-of-post-hospital-cardiac-rehabilitation-on-the-quality-of-life-of-patients-after-surgical-treatment-for-coronary-artery-disease
#16
Józefa Dąbek, Ewelina Pyka, Joanna Piotrkowicz, Krystian Stachoń, Grażyna Bonek-Wytrych
INTRODUCTION: The quality of life of cardiovascular patients is worse than that of healthy individuals. Pain, dyspnea, and fatigue impair daily activities, which in turn leads to decreased life satisfaction and emotional deterioration. The objective of comprehensive treatment, including early rehabilitation, is to reduce the risk of complications, progression, and recurrence of the disease, as well as to restore, maintain, or improve all aspects of the patient's quality of life to the greatest extent possible...
June 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28747943/the-incidence-of-aspirin-resistance-in-heart-transplantation-recipients
#17
Tomasz Urbanowicz, Anna Komosa, Michał Michalak, Tatiana Mularek, Veronica Cassadei, Stefan Grajek, Marek Jemielity
INTRODUCTION: Coronary allograft vasculopathy can cause as many deaths as infections or rejection episodes within 3 years following heart transplantation. AIM: To compare the aspirin resistance rate in an allograft heart transplantation population and in a control group by laboratory tests including the Aspirin-Resistant Patients Identification Test (ASPItest). MATERIAL AND METHODS: A total of 24 heart recipients (20 men and 4 women) at a mean age of 48 ±13 years who underwent routine clinical follow-up were consecutively enrolled in group 1...
June 2017: Kardiochirurgia i Torakochirurgia Polska, Polish Journal of Cardio-Thoracic Surgery
https://www.readbyqxmd.com/read/28747862/food-consumption-nutrient-intake-and-dietary-patterns-in-ghanaian-migrants-in-europe-and-their-compatriots-in-ghana
#18
Cecilia Galbete, Mary Nicolaou, Karlijn A Meeks, Ama de-Graft Aikins, Juliet Addo, Stephen K Amoah, Liam Smeeth, Ellis Owusu-Dabo, Kerstin Klipstein-Grobusch, Silver Bahendeka, Charles Agyemang, Frank P Mockenhaupt, Erik J Beune, Karien Stronks, Matthias B Schulze, Ina Danquah
Background: West African immigrants in Europe are disproportionally affected by metabolic conditions compared to European host populations. Nutrition transition through urbanisation and migration may contribute to this observations, but remains to be characterised. Objective: We aimed to describe the dietary behaviour and its socio-demographic factors among Ghanaian migrants in Europe and their compatriots living different Ghanaian settings. Methods: The multi-centre, cross-sectional RODAM (Research on Obesity and Diabetes among African Migrants) study was conducted among Ghanaian adults in rural and urban Ghana, and Europe...
2017: Food & Nutrition Research
https://www.readbyqxmd.com/read/28747579/effect-of-earlier-proteinuria-on-graft-functions-after-one-year-living-donor-renal-transplantation
#19
Zaiyou Dai, Luxi Ye, Dajin Chen, Xing Zhang, Meifang Wang, Rending Wang, Jianyong Wu, Jianghua Chen
BACKGROUND: Proteinuria is an indicator of subsequent renal function decline in most nephropathies and early proteinuria has been assumed to be a risk factor of poor kidney transplant outcomes. However, there is no information about the effect of earlier-proteinuria at the first week on short-term graft function after living donor renal transplantation. METHODS: Retrospective cohort study of 439 living donor kidney transplants to analyze the effect of early proteinuria at 7-day post-transplantation on short-term prognosis of living donor renal transplantation...
July 15, 2017: Oncotarget
https://www.readbyqxmd.com/read/28747511/autologous-minced-muscle-grafts-improve-endogenous-fracture-healing-and-muscle-strength-after-musculoskeletal-trauma
#20
Brady J Hurtgen, Catherine L Ward, Chrissy M Leopold Wager, Koyal Garg, Stephen M Goldman, Beth E P Henderson, Todd O McKinley, Sarah M Greising, Joseph C Wenke, Benjamin T Corona
The deleterious impact of concomitant muscle injury on fracture healing and limb function is commonly considered part of the natural sequela of orthopedic trauma. Recent reports suggest that heightened inflammation in the surrounding traumatized musculature is a primary determinant of fracture healing. Relatedly, there are emerging potential therapeutic approaches for severe muscle trauma (e.g., volumetric muscle loss [VML] injury), such as autologous minced muscle grafts (1 mm(3) pieces of muscle; GRAFT), that can partially prevent chronic functional deficits and appear to have an immunomodulatory effect within VML injured muscle...
July 2017: Physiological Reports
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