Pavel Dundr, Michaela Bártů, Tjalling Bosse, Quang Hiep Bui, David Cibula, Jana Drozenová, Pavel Fabian, Oluwole Fadare, Jitka Hausnerová, Jan Hojný, Nikola Hájková, Radek Jakša, Jan Laco, Sigurd F Lax, Radoslav Matěj, Gábor Méhes, Romana Michálková, Adam Šafanda, Kristýna Němejcová, Naveena Singh, Simona Stolnicu, Marián Švajdler, Tomáš Zima, Ivana Stružinská, W Glenn McCluggage
Primary ovarian mucinous tumors represent a heterogeneous group of neoplasms, and their diagnosis may be challenging. We analyzed 124 primary ovarian mucinous tumors originally diagnosed as mucinous borderline tumors (MBTs) or mucinous carcinomas (MCs), with an emphasis on interobserver diagnostic agreement and the potential for diagnostic support by molecular profiling using a next-generation sequencing targeted panel of 727 DNA and 147 RNA genes. Fourteen experienced pathologists independently assigned a diagnosis from preset options, based on a review of a single digitized slide from each tumor...
January 2023: Modern Pathology