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ovarian mucinous cystadenoma

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https://www.readbyqxmd.com/read/27892434/clinicomorphological-spectrum-of-ovarian-cystic-lesions
#1
R Dhakal, R Makaju, R Bastakoti
Background Ovarian cysts, which present as neoplastic and non-neoplastic lesions, are the most common gynaecological cause of hospital admissions. Early diagnosis is difficult due to asymptomatic nature. Clinical, radiological and gross examination alone cannot distinguish benign from malignant lesions, hence, histopathological examination is important for diagnostic, therapeutic and prognostic approach. Objective The objective of the study is to analyze the spectrum of ovarian cystic lesions with their clinico-morphorgical features...
January 2016: Kathmandu University Medical Journal (KUMJ)
https://www.readbyqxmd.com/read/27890095/an-unexpected-death-due-to-massive-ascites-and-a-giant-mucinous-ovarian-cystadenoma
#2
Masayuki Kashiwagi, Mio Takayama, Tomoko Sugimura, Aya Matsusue, Kenji Hara, Brian Waters, Shin-Ichi Kubo
A female in her thirties fell face down in her room. She was motionless when her sister found her. She was transported to the hospital by ambulance and was in a state of cardiopulmonary arrest on admission. She did not respond to resuscitation. Her abdomen had started to swell 3years before her death. An autopsy was performed to clarify the decedent's cause of death. She was 172cm tall and weighed 146kg. Her maximum abdominal girth was 172.1cm. A subcutaneous hemorrhage measuring 4.5cm in diameter was observed in the epigastric region...
November 2016: Legal Medicine
https://www.readbyqxmd.com/read/27801756/ovarian-epithelial-inclusions-with-mucinous-differentiation-a-clinicopathologic-study-of-42-cases
#3
Jeffrey D Seidman, Jayashree Krishnan
Ovarian epithelial inclusions lined by mucinous epithelium are rare and of uncertain origin. Ovaries containing such inclusions were studied in 42 women. The inclusions were divided into 3 groups: serous epithelial lined with typical ciliated morphology but with distinct basophilic cytoplasmic mucin in some or all of the lining cells, those lined by typical mucinous epithelium, and those lined by a combination of typical mucinous epithelium and serous epithelium. The mean patient age was 61.5 years. Pure mucinous inclusions were found in 27 patients, serous-type inclusions with cytoplasmic mucin in 20, and mixed type in 10...
October 31, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27759179/imaging-in-gynecological-disease-clinical-and-ultrasound-features-of-mucinous-ovarian-tumors
#4
F Moro, G F Zannoni, D Arciuolo, T Pasciuto, S Amoroso, F Mascilini, S Mainenti, G Scambia, A C Testa
OBJECTIVES: To describe clinical and ultrasound findings of mucinous ovarian tumors. METHODS: Patients with a histological diagnosis of mucinous ovarian tumor who had undergone preoperative ultrasound examination were retrospectively identified from a single ultrasound center. The histological examination was performed by the same pathologist in all cases. The masses were described using the terms and definitions of the International Ovarian Tumor Analysis group...
August 12, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27702736/a-huge-ovarian-mucinous-cystadenoma-associated-with-contralateral-teratoma-and-polycystic-ovary-syndrome-in-an-obese-adolescent-girl
#5
Patcharapa Thaweekul, Yuthadej Thaweekul, Karicha Mairiang
A 13-year-old, obese girl presented with acute abdominal pain with abdominal distension for a year. The physical examination revealed marked abdominal distension with a large well-circumscribed mass sized 13×20 cm. Her body mass index (BMI) was 37.8 kg/m2. An abdominal CT scan revealed a huge multiloculated cystic mass and a left adnexal mass. She had an abnormal fasting plasma glucose and low HDL-C. Laparotomy, right salpingooophorectomy, left cystectomy, lymph node biopsies and partial omentectomy were performed...
December 2016: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/27662036/primary-mucinous-carcinoma-of-the-fallopian-tube-case-report-and-review-of-literature
#6
Abigail Wheal, Robert Jenkins, Yoshiki Mikami, Nagindra Das, Lynn Hirschowitz
Primary mucinous carcinoma of the fallopian tube is extremely rare. We report the detailed characterization of a mucinous carcinoma arising in the fimbrial end of the fallopian tube in a 74-yr-old woman. The patient presented with recurrent urinary tract infection and urinary tract obstruction secondary to a large right ovarian mass. She had an appendicectomy as an 11 yr old. Serum CA-125 was raised at 239 U/mL. Computed tomographic scans showed bilateral, cystic ovarian tumors but no other intra-abdominal abnormality...
September 22, 2016: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/27570851/role-of-benign-ovarian-cysts-in-the-development-of-adenomyosis
#7
Sadaf Alam, Sajjad Ahmad, Muhammad M Khan, Sabeen Nasir, Naveed Sharif, Sara Ziaullah, Ahmareen Khalid, Fozia Rauf
OBJECTIVES: To assess the association of adenomyotic foci with co-existing benign ovarian cysts.  METHODS: This prospective cross-sectional study consisted of 100 consecutive hysterectomy specimens referred to Histopathology Section of Pathology Department, Peshawar Medical College, Peshawar, Pakistan by its attached teaching hospitals from January 2011 to December 2012. Hematoxylin and eosin stained sections were examined for adenomyotic foci and the presence of co-existent ovarian cysts...
September 2016: Saudi Medical Journal
https://www.readbyqxmd.com/read/27547742/a-huge-ovarian-mucinous-cystadenoma-causing-virilization-preterm-labor-and-persistent-supine-hypotensive-syndrome-during-pregnancy
#8
Suna Kabil Kucur, Canan Acar, Osman Temizkan, Aysim Ozagari, Ilay Gozukara, Atif Akyol
Mucinous cystadenoma (MC) of the ovary is an unilateral, multilocular cystic benign epithelial tumor. Supposed to be hormone responsive, MC reaches huge sizes during pregnancy. Aortocaval compression is common during pregnancy, especially when the pregnant woman is in the supine position. However, the compression recovers with a change in position. The authors report the first case of a huge mucinous cystadenoma of the ovary complicating pregnancy and causing virilization, premature labor, and persistent supine hypotensive syndrome...
April 2016: Autopsy & case reports
https://www.readbyqxmd.com/read/27516376/imaging-in-gynecological-disease-clinical-and-ultrasound-features-of-mucinous-ovarian-tumors
#9
F Moro, G F Zannoni, D Arciuolo, T Pasciuto, S Amoroso, F Mascilini, S Mainenti, G Scambia, A C Testa
OBJECTIVES: To describe clinical and ultrasound findings of mucinous ovarian tumors. METHODS: Patients with a histological diagnosis of mucinous ovarian tumor who had undergone preoperative ultrasound examination were retrospectively identified from a single ultrasound center. The histological examination was performed by the same pathologist in all cases. The masses were described using the terms and definitions of the International Ovarian Tumor Analysis group...
August 12, 2016: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/27509966/mdm2-expression-in-serous-and-mucinous-epithelial-tumours-of-the-ovary
#10
Shereen E Abdelaal, Fahima M Habib, Amina A Gamal El Din, Samia M Gabal, Nabila S Hassan, Nihad A Ibrahim
BACKGROUND: Different types of cancer exhibit abnormalities in cell cycle regulators. The murine double minute2(MDM2) cell cycle regulator is a protooncogene that negatively regulates the P53 tumour suppressor gene. Surface epithelial tumours constitute approximately two thirds of ovarian neoplasms. Each histologic type can be classified as benign, borderline and malignant. This study aimed to examine immunohistochemical expression of the MDM2 protein in ovarian serous and mucinous epithelial tumours (benign, borderline and malignant)...
2016: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/27446577/retroperitoneal-mucinous-cystadenoma-of-the-appendix-mimicking-hydatid-cyst-a-case-report
#11
Hasan Ediz Sikar, Kenan Çetin, Ersin Gündoğan, Gökçen Alinak Gündoğan, Levent Kaptanoğlu
Appendiceal mucocele is a cystic dilatation of the appendix due to abnormal appendiceal mucinous secretion. Cystadenoma of the appendix is one of the most common causes and is encountered in 0.6% of all appendectomy specimens. The diagnosis may be difficult due to the asymptomatic nature of the disease; pain in the right lower quadrant may be the only symptom. Complex ovarian cyst, urolithiasis or cystic hydatid disease of the liver have been reported as mimicking appendiceal mucocele in the literature. In this study, we present a case of mucinous cystadenoma of the appendix mimicking retroperitoneal hydatid cyst in a 59-year-old woman...
August 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27446571/paired-box-gene-2-is-associated-with-estrogen-receptor-%C3%AE-in-ovarian-serous-tumors-potential-theory-basis-for-targeted-therapy
#12
Min Wang, Haifen Ma
It has been suggested that Paired box gene (PAX)2 is activated by estradiol via estrogen receptor (ER)α in breast and endometrial cancer. The expression of PAX2 was restricted to ovarian serous tumors and only one case was positive in borderline mucinous tumor in our previous study. In the present study, immunohistochemistry was performed to assess the expression of ERα in 58 cases of ovarian serous tumors, including 30 serous cystadenomas, 16 borderline serous cystadenomas, 12 serous carcinomas and 67 cases of ovarian mucinous tumors, including 29 mucinous cystadenoma, 23 borderline mucinous cystadenoma and 15 mucinous carcinoma, which were the same specimens with detection of PAX2 expression...
August 2016: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/27358520/retropancreatic-ovarian-tumor
#13
Soumyo Ranjan Acharya, Prosenjit Dasgupta, Subhobroto Das, Sandip Halder, Nilanjan Panda
Retroperitoneal mucinous cystadenomas are rare lesions (less than 50 reported) characterized by presence of ovary like stroma of unknown origin. However, germinal component of ovary has never been found in them. The pancreas occasionally gives rise to mucinous cystadenomas, but they are always intrapancreatic. We report a unique case of a rare retroperitoneal mucinous cystadenomas with presence of ovarian follicles in a 45-year-old lady who presented with an abdominal mass. This was successfully excised. Though retroperitoneal mucinous cystadenomas are rare, presence of ovarian follicle (germ cell) in them has never been reported before...
June 2016: Indian Journal of Surgery
https://www.readbyqxmd.com/read/27304648/appendectomy-in-the-surgical-treatment-of-benign-ovarian-mucinous-cystadenomas-is-it-necessary
#14
Eser S Ozyurek, Uner M Karacaoglu, Erdal Kaya, Elif C Gundogdu, Eylem Odacilar
OBJECTIVES: To determine if appendectomy as an adjunctive procedure is necessary in the surgical treatment of benign ovarian mucinous cystadenomas. MATERIAL AND METHODS: Retrospective analysis of clinical data: in a research hospital, obstetrics and gynecology depart-ment setting, 63 cases of benign ovarian mucinous cystadenomas confirmed in the pathological evaluation were revised. 59 had the complete clinical, final pathological and follow-up data available and were included...
2016: Ginekologia Polska
https://www.readbyqxmd.com/read/27300746/successful-pregnancy-after-improving-insulin-resistance-with-the-glucagon-like-peptide-1-analogue-in-a-woman-with-polycystic-ovary-syndrome-a-case-report-and-review-of-the-literature
#15
Qianying Yang, Fang Wang
The polycystic ovary syndrome (PCOS) is a common cause of anovulatory infertility. It is diagnosed by the presence of hyperandrogenemia, insulin resistance (IR), obesity and other endocrine or metabolic disorders. Exenatide (EX) is a kind of glucagon-like peptide, which is a new option for patients with diabetes mellitus. We present a patient with infertility for PCOS. She was overweight and her medical history included IR, right-sided ovarian mucinous cystadenomas, and left-sided teratoma. Although she had been treated with ovarian surgery, clomiphene citrate and gonadotropins, weight loss and metformin, which have been effective for dominant follicle development, she still failed to conceive...
2016: Gynecologic and Obstetric Investigation
https://www.readbyqxmd.com/read/27052496/periampullary-diverticula-misdiagnosed-as-cystic-pancreatic-lesions-a-review-of-3-cases
#16
Chee Hui Ng, Chau Hung Lee
BACKGROUND: Cystic lesions on the pancreatic head can mimic fluid-filled duodenal or periampullary diverticula. We reviewed a series of cases in which periampullary diverticula were misdiagnosed as cystic pancreatic lesions. CASE REPORT: Case 1. A Chinese woman presented to the surgical outpatient clinic for intermittent upper abdominal discomfort. Contrast-enhanced MRI of the abdomen revealed a cystic-appearing lesion in the region of the pancreatic head, which was reported as a cystic pancreatic lesion...
2016: American Journal of Case Reports
https://www.readbyqxmd.com/read/27048105/cancer-antigens-19-9-and-125-as-tumor-markers-in-patients-with-mucinous-ovarian-tumors
#17
J D Santotoribio, A Garcia-de la Torre, C Cañavate-Solano, F Arce-Matute, M J Sanchez-del Pino, S Perez-Ramos
PURPOSE OF INVESTIGATION: To determine the accuracy of carcinoembryonic antigen (CEA), cancer antigen (CA) 15.3, CA 19.9, and CA 125 for diagnosis of mucinous ovarian cancer (MOC). MATERIALS AND METHODS: Samples were collected preoperatively from patients with mucinous ovarian tumor. The following variables were analysed: CEA, CA 15.3, CA 19.9, and CA 125. After surgery, histology and stage were determined according to FIGO-classification. Patients were classified into two groups according to the diagnosis of ovarian biopsy: NOT MOC and MOC...
2016: European Journal of Gynaecological Oncology
https://www.readbyqxmd.com/read/27030496/-effects-of-cystectomy-for-ovary-benign-cyst-on-ovarian-reserve-and-pregnancy-outcome-of-in-vitro-fertilization-embryo-transfer-cycle
#18
X R Zhang, L L Ding, R Tang, Y Sheng, Y Y Qin, Z J Chen
OBJECTIVE: To investigate the impact of previous cystectomy for ovary benign cyst on ovarian reserve and pregnancy outcome in in vitro fertilization/intracytoplasmic sperm injection-embryo transfer (IVF/ICSI-ET) cycles. METHODS: Totally 622 infertility patients were retrospectively investigated who underwent first IVF/ICSI-ET cycle in Reproductive Hospital Affiliated to Shandong University from January 2013 to June 2014. There were 153 cases who had been removed ovarian cyst by cystectomy surgeries recruited as study group, in which 44 cases of ovarian endometriosis cyst, 35 cases of benign ovarian teratomas, 67 cases of simple ovarian cyst and 7 cases of ovarian mucinous cystadenoma...
March 2016: Zhonghua Fu Chan Ke za Zhi
https://www.readbyqxmd.com/read/27029917/accuracy-of-intraoperative-frozen-section-for-the-evaluation-of-ovarian-neoplasms-an-institutional-experience
#19
Atif Ali Hashmi, Samreen Naz, Muhammad Muzzammil Edhi, Naveen Faridi, Syed Danish Hussain, Shazia Mumtaz, Mehmood Khan
BACKGROUND: Ovarian neoplasms are a heterogeneous group of tumors including surface epithelial, germ cell and sex cord stromal tumors with a subset having low malignant potential (borderline tumors). While the surgical management plan differs in different categories of tumors, preoperative diagnosis is seldom available. In these circumstances, the role of frozen section becomes invaluable. In the current study, we aimed to evaluate the accuracy of the frozen section of ovarian tumors in our setup...
2016: World Journal of Surgical Oncology
https://www.readbyqxmd.com/read/27003157/mucins-muc16-and-muc1-are-major-carriers-of-sle-a-and-sle-x-in-borderline-and-malignant-serous-ovarian-tumors
#20
Sara Ricardo, Lara Marcos-Silva, Cristina Valente, Ricardo Coelho, Rosa Gomes, Leonor David
Mucins are heavily glycosylated proteins overexpressed and associated with truncated or sialylated glycans upon malignant transformation. We previously identified a panel of four glyco-mucin profiles (MUC16/Tn, MUC16/STn, MUC1/Tn, and MUC1/STn) with 100 % specificity and 100 % positive predictive value for detection of borderline/malignant serous tumors of the ovary, using proximity ligation assay (PLA). In the present work, using the same method, we studied other mucin glycosylation profiles that might add relevant information for diagnostic purposes...
June 2016: Virchows Archiv: An International Journal of Pathology
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