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ovarian mucinous cystadenoma

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https://www.readbyqxmd.com/read/29744127/virilization-of-a-postmenopausal-woman-by-a-mucinous-cystoadenoma
#1
Sara Alonso Díaz, Belén Vega Piñero, Lía Nattero Chávez, Ignacio Pinilla Pagnon, Andrés Ortiz-Flores, Manuel Luque-Ramírez
Objective: To describe the case of the most hyperandrogenaemic ovarian mucinous cystadenoma reported to date. Methods: We present the clinical, laboratory and radiologic findings in a patient with an unusual diagnosis according to age and the clinical behaviour of the tumour, as well as a review of relevant literature. Results: A 77-year-old women came to our consult because of fronto-parietal alopecia and an augmentation of the abdominal perimeter since 1 year ago...
January 2018: Oxford Medical Case Reports
https://www.readbyqxmd.com/read/29731792/immunohistochemical-characterization-of-normal-ovary-and-common-epithelial-ovarian-neoplasm-with-a-monoclonal-antibody-to-cytokeratin-and-vimentin
#2
Ankita Goel, Nandam Mohan Rao, Vissa Santhi, Syam Sundar Byna, Bhavana Grandhi, Jyothi Conjeevaram
Background & Objective: The common epithelial ovarian tumors are classified into serous, mucinous, clear cell, endometrioid, the Brenner, mixed, and undifferentiated types. Cytoskeleton intermediate filament composition of ovarian tissues indicates that the cytokeratin and vimentin are observed in ovarian surface epithelium along with the common ovarian epithelial tumors. The current study aimed at investigating the cytokeratin and vimentin expression in epithelial ovarian tumors to establish a diagnostic relevance...
2018: Iranian Journal of Pathology
https://www.readbyqxmd.com/read/29716620/postprandial-increase-in-serum-ca125-as-a-surrogate-biomarker-for-early-diagnosis-of-ovarian-cancer
#3
Zhuowei Gu, Yifeng He, Yue Zhang, Mo Chen, Keqi Song, Yuting Huang, Qing Li, Wen Di
BACKGROUND: CA125 is a prevalently used serum biomarker for detecting ovarian cancer over the last three decades. However, it has a significant deficiency in screening for early-stage cancer. With the purpose of exploring an effective approach to improve its performance in early diagnosis, we investigated the postprandial fluctuation pattern of cancer-derived CA125 and the underlying mechanism. METHODS: In two medical centers, 551 patients sonographically diagnosed with ovarian (adnexal) cysts (< 5 cm in diameter) were enrolled and divided into five disease groups (pelvic inflammatory cysts, retention cysts, endometrioma, benign/borderline cystadenoma and malignant cysts)...
May 1, 2018: Journal of Translational Medicine
https://www.readbyqxmd.com/read/29660844/moray-micro-forceps-biopsy-improves-the-diagnosis-of-specific-pancreatic-cysts
#4
M Lisa Zhang, Ronald N Arpin, William R Brugge, David G Forcione, Omer Basar, Martha B Pitman
BACKGROUND: Making a specific diagnosis of pancreatic cysts preoperatively is difficult. The new disposable Moray micro forceps biopsy (MFB) device allows tissue sampling from the pancreatic cyst wall/septum and aims to improve diagnosis. This study compares the diagnostic performance of the MFB with the current conventional analysis of pancreatic cyst fluid (PCF). METHODS: A total of 48 patients sampled with MFB were identified. Cysts were classified as mucinous on PCF based on extracellular mucin/mucinous epithelium, carcinoembryonic antigen (CEA) levels ≥192 ng/mL, or KRAS/GNAS mutation...
April 16, 2018: Cancer Cytopathology
https://www.readbyqxmd.com/read/29610616/ovarian-strumal-carcinoid-tumour-case-report
#5
Vesna S Antovska, Milka Trajanova, Iskra Krstevska, Irena Gosheva, Jasmina Chelebieva, Irina Prodanova
BACKGROUND: Ovarian strumal carcinoid is a germ cell tumour characterised by a mixture of thyroid tissue and carcinoid. Ovarian struma is a very rare occurrence with 0.3-1% incidence of all ovarian tumours and 3% of mature teratomas. Primary carcinoid ovarian tumours are still uncommon as a part of mature teratoma or mucinous cystadenoma. There are four major variants of a carcinoid tumour: insular, trabecular, strumal and mucinous. A strumal carcinoid is an unusual form of ovarian teratoma composed of an intimate admixture of thyroid/carcinoid tissues...
March 15, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29593866/a-rare-case-of-giant-extra-ovarian-mucinous-cystadenoma-arising-from-sigmoid-mesocolon
#6
Andrew Tan, Ran Li, Mohammed Rafique, Sharon Qin, Toan Pham
An 80-year-old female presented with one month history of acutely worsening abdominal distention and pain, without features of bowel obstruction. A giant intra-abdominal simple cyst, separate from the ovaries, was seen on imaging. Initial haematological and biochemical investigations, including tumour markers, were normal. At laparotomy, the cystic tumour was discovered to arise from the sigmoid mesocolon and was resected en bloc . Histopathology revealed the tumour to be a benign extra-ovarian mucinous cystadenoma, which is a neoplasm of ovarian origin that can arise from extra-ovarian sites, including the mesentery...
March 2018: Journal of Surgical Case Reports
https://www.readbyqxmd.com/read/29415811/-simple-mucinous-cyst-of-the-pancreas-case-report-and-literature-review
#7
Maxime Hamon, Pierre Balladur, Jean-François Fléjou
Simple mucinous cyst of the pancreas is an unusual pancreatic cyst, first described by Kosmahl et al. in 2002 with 5 cases. We describe a case of simple mucinous cyst of the pancreas, followed by a literature review. The physiopathology of this cyst is still unclear. It is an epithelial cyst, presenting as unilocular cystic lesion of the pancreatic body or tail, with a clear content, and no communication with the pancreatic duct. Microscopically, the cyst is lined by mucin-producing cells with mild atypia, and contains a fibrous wall without ovarian-like stroma...
April 2018: Annales de Pathologie
https://www.readbyqxmd.com/read/29394168/low-grade-endometrioid-stromal-sarcoma-of-the-paratestis-a-novel-report-with-molecular-confirmation-of-jazf1-suz12-translocation
#8
Abbas Agaimy, Evgeny A Moskalev, Wera Weisser, Thorsten Bach, Florian Haller, Arndt Hartmann
Tumors with Müllerian-like serous or mucinous phenotypes originating in the testis and its adnexa are rare neoplasms that have been increasingly recognized in recent years. Cystadenomas with or without ovarian-type stroma, borderline tumors, and adenocarcinomas are the main documented types. Although a handful cases of putative endometrioid adenocarcinomas have been reported, to our knowledge no case of endometrial stromal-type neoplasm has ever been reported in the literature. A 59-year-old man presented with a 2 cm left intrascrotal mass that was found on sonographic examination to arise from the epididymal tail with prominent vascularization...
May 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/29373116/uncommon-hereditary-gynaecological-tumour-syndromes-pathological-features-in-tumours-that-may-predict-risk-for-a-germline-mutation
#9
REVIEW
Karuna Garg, Anthony N Karnezis, Joseph T Rabban
The most common hereditary gynaecological tumour syndromes are hereditary breast and ovarian cancer syndrome and Lynch syndrome. However, pathologists also may encounter gynaecological tumours in women with rare hereditary syndromes. Many of these tumours exhibit distinctive gross and microscopic features that are associated with a risk for an inherited gene mutation. The sensitivity and specificity of these tumour pathology features for predicting an inherited mutation vary depending on the syndrome. By recognising these tumour features, pathologists may potentially contribute to the diagnosis of an unsuspected syndrome by recommending referral of the patient for formal risk assessment by genetic counselling...
February 2018: Pathology
https://www.readbyqxmd.com/read/29258579/giant-ovarian-cyst-masquerading-as-a-massive-ascites-a-case-report
#10
Eugene Vernyuy Yeika, Derrick Tembi Efie, Paul Nkemtendong Tolefac, Joseph Nkeangu Fomengia
BACKGROUND: Giant ovarian cysts are tumours of the ovary presenting with diameters greater than 10 cm. Giant ovarian cysts have become rare in recent days as they are diagnosed and managed early due to the availability of good imaging modalities. The aim of this case report is to show how a huge cystic ovarian mass can mislead the diagnosis of ascites in a postmenopausal woman. Factors associated with late presentation of giant ovarian cysts in sub-Saharan Africa have also been discussed...
December 19, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/29250686/ovarian-strumal-carcinoid-case-report
#11
Delia Gabriela Ciobanu Apostol, Tudor Andrei BuŢureanu, Demetra Gabriela Socolov, Daniela Claudia Scripcaru, Oana LuminiŢa Rosin, Ludmila Lozneanu
Strumal carcinoid represents a rare form of ovarian teratoma, consisting of both thyroid tissue and carcinoid structures. The carcinoid component is a well-differentiated neuroendocrine tumor with excellent prognosis. Strumal carcinoid tumors are commonly found in peri-menopausal women who are not usually interested in preserving their fertility and who are thus open to radical surgical treatment. In this report, we present a 24-year-old, nulliparous patient with strumal carcinoid, confirmed by histopathology and a large panel of immunohistochemistry (IHC) markers, who wished to preserve her fertility...
2017: Romanian Journal of Morphology and Embryology, Revue Roumaine de Morphologie et Embryologie
https://www.readbyqxmd.com/read/29137100/ultrasonic-and-pathological-characteristics-of-ovarian-mucinous-cystic-tumors-with-malignant-mural-nodules-two-cases-report
#12
Yan Zhang, Zheng Yuan, Kai Sun, Peifeng Li
RATIONALE: Sarcomatous or anaplastic carcinoma mural nodules presenting in ovarian mucinous cystic tumors are very rare. Here, we reported the ultrasonic and pathological features of 2 such cases. PATIENT CONCERNS: A 60-year-old woman presented with a complaint of lower abdominal pain. Physical examination revealed a hard, palpable mass in her right lower abdomen with mild tenderness. In addition, a 48-year-old woman presented with left abdominal pain and abdominal fullness...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29121977/intrahepatic-biliary-cystadenoma-mimicking-hydatid-cyst-of-liver-a-clinicopathologic-study-of-six-cases
#13
Zubair Ahmad, Nasir Uddin, Wasim Memon, Jamshid Abdul-Ghafar, Arsalan Ahmed
BACKGROUND: Intrahepatic biliary cystadenomas are rare hepatic neoplasms, which are usually cystic. These tumors are often misdiagnosed as simple liver cysts and hydatid cysts clinically and radiologically owing to nonspecific clinical and radiologic features. These tumors require complete resection, as recurrence and malignant transformation can occur following incomplete excision. It is essential that these tumors be diagnosed accurately so that they can be adequately excised. METHODS: Clinical and radiological features of six cases of biliary cystadenoma are described...
November 10, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29016404/hepatobiliary-mucinous-cystic-neoplasms-with-ovarian-type-stroma-so-called-hepatobiliary-cystadenoma-cystadenocarcinoma-clinicopathologic-analysis-of-36-cases-illustrates-rarity-of-carcinomatous-change
#14
Brian Quigley, Michelle D Reid, Burcin Pehlivanoglu, Malcolm H Squires, Shishir Maithel, Yue Xue, Choi Hyejeong, Gizem Akkas, Takashi Muraki, David A Kooby, Juan M Sarmiento, Ken Cardona, Aarti Sekhar, Alyssa Krasinskas, Volkan Adsay
The literature is highly conflicting on hepatobiliary mucinous cystic neoplasms (MCNs), aka "hepatobiliary cystadenoma/cystadenocarcinoma," largely because ovarian stroma (OS) was not a requirement until WHO-2010 and is not widely applied even today. In this study, MCNs (with OS) accounted for 24 of 229 (11%) resected hepatic cysts in one institution. Eight of the 32 (25%) cysts that had been originally designated as hepatobiliary cystadenoma/cystadenocarcinoma at the time of diagnosis proved not to have an OS during this review and were thus re-classified as non-MCN...
January 2018: American Journal of Surgical Pathology
https://www.readbyqxmd.com/read/28930625/ectopic-adrenal-tissue-associated-with-borderline-mucinous-cystadenoma-of-ovary-a-case-report-with-review-of-the-literature
#15
Kah Teik Chew, Muhammad Azrai Abu, Yulianty Arifuddin, Nor Azlin Mohamed Ismail, Noor Ain Mohd Nasir, Fazarina Mohammed, Abdul Ghani Nur Azurah
Ectopic adrenal tissue in the ovary is a rare entity. We reported a case of ectopic adrenal tissue in borderline mucinous cystadenoma of the left ovary. A 22 year-old student presented with progressive abdomen distension associated with discomfort for 3 months. Imaging investigation was suggestive of mucinous left ovarian cyst. Left salpingo-oophorectomy was performed and the histopathology revealed borderline mucinous cystadenoma with an incidental finding of ectopic adrenal tissue. This is an interesting case because of its rarity and potential risk of neoplasm changes...
September 20, 2017: Hormone Molecular Biology and Clinical Investigation
https://www.readbyqxmd.com/read/28913150/features-of-ovarian-brenner-tumors-experience-of-a-single-tertiary-center
#16
Batuhan Turgay, Kazibe Koyuncu, Salih Taşkın, Uğur Fırat Ortaç
OBJECTIVE: Brenner tumors are rare neoplasms of the ovary. The aim of this study was to investigate the clinical features of Brenner tumors. MATERIALS AND METHODS: The clinical features of 22 patients who were treated in Ankara University Faculty of Medicine Obstetrics and Gynecology Department between 2005 and 2015 were evaluated retrospectively from hospital medical records. RESULTS: The patients were aged 34 to 79 years at the time of diagnosis and the mean age was 55...
June 2017: Turkish Journal of Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28782867/imaging-in-gynecological-disease-11-clinical-and-ultrasound-features-of-mucinous-ovarian-tumors
#17
F Moro, G F Zannoni, D Arciuolo, T Pasciuto, S Amoroso, F Mascilini, S Mainenti, G Scambia, A C Testa
OBJECTIVE: To describe the clinical and ultrasound findings in patients with mucinous ovarian tumors. METHODS: In this retrospective study, women with a histological diagnosis of mucinous ovarian tumor who had undergone preoperative ultrasound examination were identified from the database of a single ultrasound center. The histological examination was performed by the same pathologist in all cases, and the ultrasound appearance of the tumors was described using the terms and definitions of the International Ovarian Tumor Analysis group...
August 2017: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/28700429/mucosal-proliferations-in-completely-examined-fallopian-tubes-accompanying-ovarian-low-grade-serous-tumors-neoplastic-precursor-lesions-or-normal-variants-of-benign-mucosa
#18
Rebecca J Wolsky, Matt A Price, Charles J Zaloudek, Joseph T Rabban
Malignant transformation of the fallopian tube mucosa, followed by exfoliation of malignant cells onto ovarian and/or peritoneal surfaces, has been implicated as the origin of most pelvic high-grade serous carcinoma. Whether a parallel pathway exists for pelvic low-grade serous tumors [ovarian serous borderline tumor (SBT) and low-grade serous carcinoma (LGSC)] remains to be fully elucidated. The literature is challenging to interpret due to variation in the diagnostic criteria and terminology for cytologically low-grade proliferations of the fallopian tube mucosa, as well as variation in fallopian tube specimen sampling...
July 11, 2017: International Journal of Gynecological Pathology
https://www.readbyqxmd.com/read/28511463/unusually-high-serum-levels-of-ca-19-9-in-an-ovarian-tumour-malignant-or-benign
#19
Divya Pandey, Ritu Sharma, Shakti Sharma, Sudha Salhan
Carbohydrate antigen 19-9 (CA 19-9) is a tumour marker found to be elevated in some ovarian tumours. We share our experience with a 55-year-old postmenopausal lady with unusually high CA19-9 levels arising from a benign mucinous cystadenoma of the ovary. The levels returned to normal eight weeks following staging laparotomy and a total abdominal hysterectomy with bilateral salpingo-oopherectomy. This report shows rare and significant elevation of CA 19-9 levels with benign mucinous cystadenomas of the ovary thus showing that women with unusually elevated tumour markers may actually harbour benign disease...
March 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28488545/determination-of-braf-v600e-ve1-protein-expression-and-braf-gene-mutation-status-in-codon-600-in-borderline-and-low-grade-ovarian-cancers
#20
Pawel Sadlecki, Pawel Walentowicz, Magdalena Bodnar, Andrzej Marszalek, Marek Grabiec, Malgorzata Walentowicz-Sadlecka
Epithelial ovarian tumors are a group of morphologically and genetically heterogeneous neoplasms. Based on differences in clinical phenotype and genetic background, ovarian neoplasms are classified as low-grade and high-grade tumor. Borderline ovarian tumors represent approximately 10%-20% of all epithelial ovarian masses. Various histological subtypes of ovarian malignancies differ in terms of their risk factor profiles, precursor lesions, clinical course, patterns of spread, molecular genetics, response to conventional chemotherapy, and prognosis...
May 2017: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
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