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https://www.readbyqxmd.com/read/29924894/an-unusual-source-of-electromagnetic-interference
#1
Kunal Pradip Verma, David Adam
A 62 year old male presented to his treating cardiologist for routine interrogation of his implantable cardiac defibrillator (ICD) on the background of severe ischaemic cardiomyopathy and end-stage kidney disease on haemodialysis. The device log revealed multiple paroxysms of atrial fibrillation (AF); however, upon scrutinising these episodes it was evident that they always corresponded to episodes of haemodialysis whilst dialysing through a chronic dialysis catheter, but not whilst dialysing via an arteriovenous fistula...
June 20, 2018: Pacing and Clinical Electrophysiology: PACE
https://www.readbyqxmd.com/read/29921962/differences-in-the-prevalence-of-sarcopenia-in-peritoneal-dialysis-patients-using-hand-grip-strength-and-appendicular-lean-mass-depends-upon-guideline-definitions
#2
Asmat Abro, Lara-Anne Delicata, Surachet Vongsanim, Andrew Davenport
BACKGROUND: Peritoneal dialysis (PD) patients with sarcopenia have increased risk of mortality. There is consensus that sarcopenia should combine assessments of muscle function and mass. We wished to determine the effect of using different operational definitions in PD patients. METHODS: Hand grip strength (HGS) and segmental bioimpedance derived appendicular lean mass (ALM) were measured and the prevalence of sarcopenia determined using the Foundation for the National Institutes of Health Sarcopenia Project (FNIH), European Working Group on Sarcopenia Older Persons (EWGSOP), and Asian Working Group on Sarcopenia (AWGS) definitions...
June 19, 2018: European Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/29920874/the-importance-of-residual-kidney-function-in-haemodialysis-patients
#3
REVIEW
Jessica Kong, Matthew Davies, Peter Mount
In contrast to peritoneal dialysis, residual kidney function is commonly disregarded for haemodialysis patients, and not regularly monitored or taken into account in routine clinical care. This is despite evidence that higher levels of residual kidney function in haemodialysis patients associate with better outcomes including survival, total solute clearance, nutrition, inflammation, and fluid balance. This review aims to summarise the clinical effects of residual kidney function specifically in haemodialysis patients...
June 19, 2018: Nephrology
https://www.readbyqxmd.com/read/29920780/epidemiology-risk-factors-and-impact-of-bacterial-infections-on-outcomes-for-pancreatic-grafts
#4
Marta Bodro, Joana Ferrer, María José Ricart, Gemma Sanclemente, Laura Linares, Carlos Cervera, Federic Cofan, Pedro Ventura, Miguel Ángel Lopez-Boado, Francesc Marco, Josep Fuster, Juan Carlos García-Valdecasas, Asunción Moreno
We aimed to determine the epidemiology, risk factors, and impact of bacterial infection on pancreatic function after pancreas transplantation. Data for pancreas transplant recipients were retrospectively reviewed between 2000 and 2014 for at least one year. We collected and analysed post-transplant data for bacterial infection, morbidity, and mortality. During the study period, 312 pancreas transplants were performed. In total, 509 episodes of bacterial infection were diagnosed in 191 patients (61%). Multidrug-resistant (MDR) organisms were present in 173 of the 513 isolated microorganisms (33%)...
June 19, 2018: Clinical Transplantation
https://www.readbyqxmd.com/read/29917254/erectile-function-and-gonadal-hormones-levels-in-men-with-end-stage-renal-disease-it-s-relevance-to-duration-of-haemodialysis
#5
Abul-Fotouh Ahmed, Mahmoud Shaban, Abdullah Daoud, Nagah Mohamed, Ahmed Solyman, Ahmed Fahim
In this study, we evaluated the relationship between haemodialysis (HD) duration and erectile function status and gonadal hormones serum levels in adult men with end-stage renal disease (ESRD). A total of 118 men with ESRD on chronic HD were eligible for analysis. The erectile dysfunction (ED) was defined and graded according to the international index of erectile function (IIEF-5) score. The serum levels of follicle stimulating hormones (FSH), luteinising hormone (LH), testosterone (TST), prolactin (PRL) and estradiol (E2) were measured using the standard laboratory technique...
June 19, 2018: Andrologia
https://www.readbyqxmd.com/read/29915661/multifactorial-aetiology-for-non-uremic-calciphylaxis-a-case-report
#6
Sijan Basnet, Niranjan Tachamo, Rashmi Dhital, Biswaraj Tharu
Calciphylaxis is commonly associated with end-stage renal disease patients on haemodialysis. We present a rare case of calciphylaxis in a non-uremic patient. The diagnosis was made clinically and confirmed with skin biopsy showing calcification of the dermal and subcutaneous tissues in the von Kossa stain. We believe that the combination of uncontrolled diabetes mellitus, a non-functioning paraganglioma and vitamin D deficiency in a susceptible female patient was responsible for causing calciphylaxis in our patient...
2018: Journal of Community Hospital Internal Medicine Perspectives
https://www.readbyqxmd.com/read/29912988/severe-secondary-hyperparathyroidism-in-patients-on-haemodialysis-is-associated-with-a-high-initial-serum-parathyroid-hormone-and-beta-crosslaps-level-results-from-an-incident-cohort
#7
Guillaume Jean, Marie Hélène Lafage-Proust, Jean Claude Souberbielle, Sylvain Lechevallier, Patrik Deleaval, Christie Lorriaux, Jean Marc Hurot, Brice Mayor, Manolie Mehdi, Charles Chazot
BACKGROUND: Secondary hyperparathyroidism (SHPT) is a frequent complication of renal disease and most commonly occurs in patients on haemodialysis (HD) with metabolic, vascular, endocrine, and bone complications. The aim of this study was to analyze the evolution of mineral metabolism parameters during the first 36 months of HD treatment and identify the initial factors associated with severe SHPT. METHODS: Serum parathyroid hormone (PTH), calcium and phosphate levels were measured monthly; bone-specific alkaline phosphatase (b-ALP) and beta-CrossLaps (CTX) were measured biannually...
2018: PloS One
https://www.readbyqxmd.com/read/29912346/a-unidimensional-diffusion-model-applied-to-uremic-toxin-kinetics-in-haemodiafiltration-treatments
#8
Miquel Gomez, Francisco Maduell
Kinetic modelling in haemodialysis is usually based upon the resolution of volume-defined compartment models. The interaction among these compartments is described by purely diffusive processes. In this paper we present an alternative kinetic model for uremic toxins in post-dilutional haemodiafiltration treatments by means of a unidimensional diffusion equation. A wide range of solutes such as urea, creatinine, $\beta _{2}$-microglobulin, myoglobin and prolactin were studied by imposing appropriate boundary and initial conditions in a virtual [0,1] domain...
June 15, 2018: Mathematical Medicine and Biology: a Journal of the IMA
https://www.readbyqxmd.com/read/29908897/impacts-of-parathyroidectomy-on-calcium-and-phosphorus-metabolism-disorder-arterial-calcification-and-arterial-stiffness-in-haemodialysis-patients
#9
Zhuo Gao, Xiaomei Li, Jing Miao, Lide Lun
BACKGROUND: Secondary hyperparathyroidism (SHPT) and calcium and phosphorus metabolism disorder are important complications in haemodialysis patients. Parathyroidectomy (PTX) may prevent or delay the progress of vascular calcification in haemodialysis patients. OBJECTIVE: To investigate the impacts of PTX on calcium and phosphorus metabolism, arterial calcification and arterial stiffness in haemodialysis patients with SHPT. METHODS: Twenty-one SHPT-haemodialysis patients were selected for PTX...
June 13, 2018: Asian Journal of Surgery
https://www.readbyqxmd.com/read/29905580/iron-therapy-for-managing-anaemia-in-chronic-kidney-disease
#10
Iain C Macdougall
PURPOSE OF REVIEW: Iron deficiency is a major contributory cause to the development of anaemia in chronic kidney disease (CKD), and thus, iron replacement therapy plays a critical role in the management of this condition. The two main routes for administering iron are oral and intravenous, and there have been a number of new publications relevant to both routes of administration. RECENT FINDINGS: Recent developments on the topic of iron management in CKD include the introduction of new oral iron preparations, as well as two recent meta-analyses on iron therapy in CKD (one on oral versus intravenous iron, and one on high- versus low-dose intravenous iron in haemodialysis patients)...
June 13, 2018: Current Opinion in Nephrology and Hypertension
https://www.readbyqxmd.com/read/29903522/vascular-access-clinic-results-before-and-after-implementing-a-multidisciplinary-approach-adding-routine-doppler-ultrasound
#11
Inés Aragoncillo Sauco, José Manuel Ligero Ramos, Almudena Vega Martínez, Ángel Luis Morales Muñoz, Soraya Abad Estébanez, Nicolás Macías Carmona, Diego Ruiz Chiriboga, Rosario García Pajares, Teresa Cervera Bravo, Juan Manuel López-Gómez, Soledad Manzano Grossi, Elena Menéndez Sánchez, Javier Río Gomez, Ana María García Prieto, Tania Linares Grávalos, Fernando Garcia Boyano, Luis Manuel Reparaz Asensio, Marta Albalate Ramón, Patricia de Sequera Ortiz, Beatriz Gil Casares, Jara Ampuero Mencía, Sandra Castellano, Belén Martín Pérez, José Luís Martín Conty, Alba Santos Garcia, José Luño Fernandez
BACKGROUND: A multidisciplinary approach and Doppler ultrasound (DU) assessment for the creation and maintenance of arteriovenous fistulas (AVF) for haemodialysis can improve prevalence and patency. The aim of this study was to analyse the impact of a new multidisciplinary vascular access (VA) clinic with routine DU. MATERIAL AND METHODS: We analysed the VA clinic results from 2014 and 2015, before and after the implementation of a multidisciplinary team protocol (vascular surgeon/nephrologist) with routine DU in preoperative mapping and prevalent AVF...
June 11, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29893920/superior-vena-cava-stenosis-in-haemodialysis-patients-with-a-tunnelled-cuffed-catheter-prevalence-and-risk-factors
#12
Laura Labriola, Benjamin Seront, Ralph Crott, Pauline Borceux, Frank Hammer, Michel Jadoul
Background: Although superior vena cava (SVC) stenosis may be a life-threatening complication of haemodialysis (HD) catheters, its prevalence and risk factors in HD patients are unknown. Our aim was to assess the prevalence and risk factors for SVC stenosis in HD patients with a tunnelled cuffed catheter (TCC) and to describe its clinical presentation. Methods: In this single-centre, retrospective cohort study, all in-centre chronic HD patients carrying a TCC (1 January 2008-31 December 2012) were included (n = 117 patients, 214 TCC, 80 911 catheter-days)...
June 8, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29875061/the-anaemia-control-model-does-it-help-nephrologists-in-therapeutic-decision-making-in-the-management-of-anaemia
#13
María Laura Bucalo, Carlo Barbieri, Susana Roca, Jasmine Ion Titapiccolo, Maria Soledad Ros Romero, Rosa Ramos, Mercedes Albaladejo, Diana Manzano, Flavio Mari, Manuel Molina
INTRODUCTION: Anaemia is common in haemodialysis patients and treating it with erythropoiesis-stimulating agents (ESAs) is complex due to many factors. OBJECTIVES: To assess the usefulness of the Anaemia Control Model (ACM) in the treatment of anaemia in haemodialysis. METHODS: ACM is a software that predicts the optimal dose of darbepoetin and iron sucrose to achieve target haemoglobin (Hb) and ferritin levels, and makes prescription suggestions...
June 3, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29871769/haemodialysis-related-heparin-induced-thrombocytopenia-case-series-and-literature-review
#14
Joana Gameiro, Sofia Jorge, José António Lopes
Heparin-induced thrombocytopenia (HIT) is a serious and life-threatening complication that occurs in five per cent of patients exposed to heparin. It should be considered in patients with a platelet count <100×109 cells/l or a >50% decrease from baseline count in association with heparin therapy. Thromboembolic complications develop in 50% of patients. Bleeding is rare as the platelet count nadir typically does not drop below 20×109 cells/l. Up to 12% of dialysis patients develop HIT, named haemodialysis-related-heparin-induced thrombocytopenia (HD-HIT), as they are a risk group with continuous exposure to heparin...
June 2, 2018: Nefrología: Publicación Oficial de la Sociedad Española Nefrologia
https://www.readbyqxmd.com/read/29869117/validating-the-use-of-bioimpedance-spectroscopy-for-assessment-of-fluid-status-in-children
#15
Indranil Dasgupta, David Keane, Elizabeth Lindley, Ihab Shaheen, Kay Tyerman, Franz Schaefer, Elke Wühl, Manfred J Müller, Anja Bosy-Westphal, Hans Fors, Jovanna Dahlgren, Paul Chamney, Peter Wabel, Ulrich Moissl
BACKGROUND: Bioimpedance spectroscopy (BIS) with a whole-body model to distinguish excess fluid from major body tissue hydration can provide objective assessment of fluid status. BIS is integrated into the Body Composition Monitor (BCM) and is validated in adults, but not children. This study aimed to (1) assess agreement between BCM-measured total body water (TBW) and a gold standard technique in healthy children, (2) compare TBW_BCM with TBW from Urea Kinetic Modelling (UKM) in haemodialysis children and (3) investigate systematic deviation from zero in measured excess fluid in healthy children across paediatric age range...
June 4, 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/29866727/impact-of-the-pretransplant-dialysis-modality-on-kidney-transplantation-outcomes-a-nationwide-cohort-study
#16
Huan-Tang Lin, Fu-Chao Liu, Jr-Rung Lin, See-Tong Pang, Huang-Ping Yu
OBJECTIVE: Most patients with uraemia must undergo chronic dialysis while awaiting kidney transplantation; however, the role of the pretransplant dialysis modality on the outcomes of kidney transplantation remains obscure. The objective of this study was to clarify the associations between the pretransplant dialysis modality, namely haemodialysis (HD) or peritoneal dialysis (PD), and the development of post-transplant de novo diseases, allograft failure and all-cause mortality for kidney-transplant recipients...
June 4, 2018: BMJ Open
https://www.readbyqxmd.com/read/29866671/treatment-of-extreme-hypercalcaemia-the-role-of-haemodialysis
#17
Anna B Basok, Boris Rogachev, Yosef Shmuel Haviv, Marina Vorobiov
A patient with extremely high calcium level of 23.9 mg/dL (5.97 mmol/L) was admitted to our department unconscious with pathological ECG recording, demonstrating shortening of QT interval. The patient was treated by fluid resuscitation, bisphosphonates, salmon calcitonin and steroids. Haemodialysis with low calcium bath had been promptly provided with improvement of consciousness and calcium level. ECG changes disappeared. Subsequent investigations revealed hyperparathyroidism and a large parathyroid adenoma was then surgically removed...
June 4, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29865146/impact-of-vitamin-d-on-the-cardiovascular-system-in-advanced-chronic-kidney-disease-ckd-and-dialysis-patients
#18
REVIEW
Anna Gluba-Brzózka, Beata Franczyk, Aleksandra Ciałkowska-Rysz, Robert Olszewski, Jacek Rysz
In patients suffering from chronic kidney disease (CKD), the prevalence of cardiovascular disease is much more common than in the general population. The role of vitamin D deficiency had been underestimated until a significant association was found between vitamin D therapy and survival benefit in haemodialysis patients. Vitamin D deficiency is present even in the early stages of chronic kidney disease. The results of experimental studies have revealed the relationship between vitamin D deficiency and impairment of cardiac contractile function, higher cardiac mass and increased myocardial collagen content...
June 1, 2018: Nutrients
https://www.readbyqxmd.com/read/29864754/treatment-of-a-patient-with-psychotic-disorder-undergoing-haemodialysis-a-case-report
#19
Arijana Turčin
We report a case of a 35-year old male patient that was in treatment for chronic kidney failure for 20 years, with a personal history of unsuccessful kidney transplantation and undergoing continuous haemodialysis. He had to be treated psychiatrically for the first time because of exacerbation of psychotic symptoms. He was hospitalized twice in succession, because of the severity of the psychotic symptoms that included imperative auditory hallucinations that also led to a serious suicidal attempt. The prescribed psychiatric therapy had to be adjusted in type, dosage and especially the time of administration as his psychiatric status fluctuated every two days in sync with the wash-out of medication due to haemodialysis...
June 2018: Psychiatria Danubina
https://www.readbyqxmd.com/read/29860419/acetate-free-citrate-acidified-bicarbonate-dialysis-improves-serum-calcification-propensity-a-preliminary-study
#20
Georg Lorenz, Christopher C Mayer, Quirin Bachmann, Sarah Stryeck, Matthias C Braunisch, Bernhard Haller, Javier Carbajo-Lozoya, Alina Schmidt, Simon Witthauer, Jasmin Abuzahu, Stephan Kemmner, Susanne Angermann, Naresh Koneru, Siegfried Wassertheurer, Richard Bieber, Uwe Heemann, Tobias Madl, Andreas Pasch, Christoph Schmaderer
Background: A novel in vitro test (T50 test) assesses ex vivo serum calcification propensity and predicts mortality in chronic kidney disease and haemodialysis (HD) patients. For the latter, a time-dependent decline of T50 was shown to relate to mortality. Here we assessed whether a 3-month switch to acetate-free, citrate-acidified, standard bicarbonate HD (CiaHD) sustainably improves calcification propensity. Methods: T50 values were assessed in paired midweek pre-dialysis sera collected before and 3 months after CiaHD in 78 prevalent European HD patients...
May 30, 2018: Nephrology, Dialysis, Transplantation
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