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https://www.readbyqxmd.com/read/29652680/impact-of-intra-operative-fluid-and-noradrenaline-administration-on-early-postoperative-renal-function-after-cystectomy-and-urinary-diversion-a-retrospective-observational-cohort-study
#1
Marc A Furrer, Marc P Schneider, Lukas M Löffel, Fiona C Burkhard, Patrick Y Wuethrich
BACKGROUND: The use of noradrenaline to enable a restrictive approach to intra-operative fluid therapy to avoid salt and water overload has gained increasing acceptance. However, concerns have been raised about the impact of this approach on renal function. OBJECTIVES: To identify risk factors for acute kidney injury (AKI) in patients undergoing cystectomy with urinary diversion and determine whether administration of noradrenaline and intra-operative hydration regimens affect early postoperative renal function...
April 12, 2018: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/29649802/is-there-not-sufficient-evidence-to-show-that-haemodiafiltration-is-superior-to-conventional-haemodialysis-in-treating-end-stage-kidney-disease-patients
#2
Bernard Canaud, Ellen Busink, Christian Apel, Sudhir K Bowry
No abstract text is available yet for this article.
April 12, 2018: Blood Purification
https://www.readbyqxmd.com/read/29644070/intravenous-drug-users-who-require-dialysis-causes-of-renal-failure-and-outcomes
#3
Jemima K Scott, Dominic M Taylor, Chris R K Dudley
Background: Intravenous drug use is associated with progressive kidney disease of several aetiologies. It is associated with behavioural and lifestyle characteristics that make the provision of renal replacement therapies (RRTs) challenging. We observed that patients who use intravenous drugs [people who inject drugs (PWID)] present late to renal services and struggle to engage with treatment. We describe the experience of a UK centre providing renal services to a mixed city and rural population...
April 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29644064/intensive-haemodialysis-using-pmma-dialyser-does-not-increase-renal-response-rate-in-multiple-myeloma-patients-with-acute-kidney-injury
#4
Laurent Hudier, Olivier Decaux, Atmann Haddj-Elmrabet, Marie Lino, Lise Mandart, Pascale Siohan, Eric Renaudineau, Theophile Sawadogo, Thierry Lamy De La Chapelle, Emmanuel Oger, Frank Bridoux, Cécile Vigneau
Background: Intensive haemodialysis (IHD) in addition to bortezomib-based chemotherapy might be efficient to rapidly decrease serum immunoglobulin-free light chains removal in patients with multiple myeloma (MM) and to improve renal prognosis and survival. Methods: The aim of this retrospective multi-centre study was to compare the efficacy (renal recovery rate) of IHD and of standard haemodialysis (SHD) in patients with MM and dialysis-dependent acute kidney injury (AKI), concomitantly treated with bortezomib-based chemotherapy...
April 2018: Clinical Kidney Journal
https://www.readbyqxmd.com/read/29642725/comparison-of-methods-to-estimate-haemodialysis-urea-clearance
#5
Ahmed Mohamed, Andrew Davenport
INTRODUCTION: Dialysis adequacy is traditionally measured by monthly blood urea sampling and calculating sessional Kt/Vurea. Modern dialysis machines can estimate clearances each session, so we wished to compare online measurements with standard Kt/Vurea. METHODS: Urea clearance was estimated by intermittent changes in effective ionic dialysance and by continuous ultraviolet light absorption spent during the mid-week dialysis session. Total body water was calculated by the Watson equation and measured by multifrequency bioimpedance...
April 1, 2018: International Journal of Artificial Organs
https://www.readbyqxmd.com/read/29623579/pharmacokinetics-safety-and-tolerability-of-oral-semaglutide-in-subjects-with-renal-impairment
#6
Charlotte Granhall, Flemming L Søndergaard, Mette Thomsen, Thomas W Anderson
BACKGROUND: Semaglutide, a glucagon-like peptide-1 (GLP-1) analogue, has been co-formulated with the absorption enhancer sodium N-(8-[2-hydroxybenzoyl] amino) caprylate (SNAC) as a tablet for oral administration. This trial (NCT02014259) investigated the pharmacokinetics, safety and tolerability of oral semaglutide in subjects with and without renal impairment. METHODS: Subjects were categorised as having normal renal function (n = 24), mild (n = 12), moderate (n = 12) or severe (n = 12) renal impairment, or end-stage renal disease (ESRD) requiring haemodialysis (n = 11) and received once-daily oral semaglutide (5 mg for 5 days followed by 10 mg for 5 days) in the fasting state, followed by 30 min fasting after dosing...
April 6, 2018: Clinical Pharmacokinetics
https://www.readbyqxmd.com/read/29622705/native-valve-endocarditis-fusarium-and-end-stage-renal-disease
#7
Supradip Ghosh, Atul Phillips, Sonali Ghosh, Amandeep Singh
We would like to report a case of invasive Fusariosis involving the native mitral valve and complicated by septic thromboembolism. The patient was a known case of end-stage renal disease on maintenance haemodialysis and did not have any of the known risk factors for invasive Fusariosis like neutropaenia, severe T cell immunodeficiency, postsolid organ transplant recipients, posthaematopoietic stem cell transplant recipients and patients who received cytotoxic and/or high-dose corticosteroid therapy.
April 5, 2018: BMJ Case Reports
https://www.readbyqxmd.com/read/29616470/peritoneal-dialysis-as-initial-dialysis-modality-a-viable-option-for-late-presenting-end-stage-renal-disease
#8
REVIEW
Muhammad Masoom Javaid, Behram Ali Khan, Srinivas Subramanian
Late-presenting end-stage renal disease is a significant problem worldwide. Up to 70% of patients start dialysis in an unplanned manner without a definitive dialysis access in place. Haemodialysis via a central venous catheter is the default modality for the majority of such patients, and peritoneal dialysis is usually not considered as a feasible option. However, in the recent years, some reports on urgent-start peritoneal dialysis in the late-presenting end-stage renal disease have been published. The collective experience shows that PD can be a safe, efficient and cost-effective alternative to haemodialysis in late-presenting end-stage renal disease with comparable outcomes to the conventional peritoneal dialysis and urgent-start haemodialysis...
April 3, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/29614907/haemodialysis-access-thrombosis-outcomes-after-surgical-thrombectomy-versus-catheter-directed-thrombolytic-infusion
#9
Linn Koraen-Smith, Matteus Krasun, Matteo Bottai, Ulf Hedin, Carl M Wahlgren, Peter Gillgren
INTRODUCTION: Thrombosis is one of the most common complications of dialysis vascular access and is a significant source of morbidity and healthcare-associated costs. In this retrospective study, outcomes for surgical thrombectomy and thrombolysis after access thrombosis in patients with arteriovenous fistulas or prosthetic grafts (arteriovenous grafts) were analysed. METHODS: All patients with a primary episode of dialysis access thrombosis between 2005 and 2013 were included which yielded 131 patients with 149 episodes of access thrombosis (108 arteriovenous grafts; 41 arteriovenous fistulas)...
April 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29611250/differences-in-the-prevalence-of-sarcopenia-in-haemodialysis-patients-the-effects-of-gender-and-ethnicity
#10
S Yoowannakul, K Tangvoraphonkchai, S Vongsanim, A Mohamed, A Davenport
BACKGROUND: There is no universal consensus definition of sarcopenia, although there is agreement that sarcopenia is a risk factor for mortality in haemodialysis (HD) patients. We aimed to determine the effect of using different operational definitions in a multiracial group of HD patients. METHODS: We measured hand grip strength (HGS) and appendicular lean mass (ALM) by segmental bioimpedance using the Foundation for the National Institutes of Health Sarcopenia Project (FNIH), European Working Group on Sarcopenia (EWGS) and Asian Working Group on Sarcopenia definitions for HGS weakness and loss of appendicular lean mass...
April 2, 2018: Journal of Human Nutrition and Dietetics: the Official Journal of the British Dietetic Association
https://www.readbyqxmd.com/read/29611180/antimicrobial-lock-solutions-for-preventing-catheter-related-infections-in-haemodialysis
#11
REVIEW
Maria C Arechabala, Maria I Catoni, Juan Carlos Claro, Noelia P Rojas, Miriam E Rubio, Mario A Calvo, Luz M Letelier
BACKGROUND: Patients undergoing haemodialysis (HD) through a central venous catheter (CVC) are exposed to several risks, being a catheter-related infection (CRI) and a CVC lumen thrombosis among the most serious. Standard of care regarding CVCs includes their sealing with heparin lock solutions to prevent catheter lumen thrombosis. Other lock solutions to prevent CRI, such as antimicrobial lock solutions, have proven useful with antibiotics solutions, but not as yet for non-antibiotic antimicrobial solutions...
April 3, 2018: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/29609535/prevalence-and-correlates-of-central-venous-catheter-use-among-haemodialysis-patients-in-the-irish-health-system-a-national-study
#12
Wael F Hussein, Husham Mohammed, Leonard Browne, Liam Plant, Austin G Stack
BACKGROUND: Central venous catheters (CVC) are associated with substantial morbidity and mortality among patients undergoing haemodialysis (HD), yet they are frequently used as the primary vascular access for many patients on HD. The goal of this study was to determine the prevalence and variation in CVC use across centres in the Irish health system. METHODS: Data from the National Kidney Disease Clinical Patient Management System (KDCPMS) was used to determine CVC use and patterns across centres...
April 2, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29608708/effects-of-intradialytic-cycling-exercise-on-exercise-capacity-quality-of-life-physical-function-and-cardiovascular-measures-in-adult-haemodialysis-patients-a-systematic-review-and-meta-analysis
#13
Hannah M L Young, Daniel S March, Matthew P M Graham-Brown, Arwel W Jones, Ffion Curtis, Charlotte S Grantham, Darren R Churchward, Patrick Highton, Alice C Smith, Sally J Singh, Chris Bridle, James O Burton
Background: Intradialytic cycling (IDC), delivered during haemodialysis (HD), has the potential to improve many health issues. This systematic review and meta-analysis examine the evidence on the effects of IDC on exercise capacity, quality of life (QoL), physical function and cardiovascular health. Methods: Twenty-four databases were searched alongside Internet and hand searching, and consultation with experts. Eligibility criteria were cluster randomized, randomized and quasi-randomized controlled trials (RCTs) of IDC versus usual care in prevalent adult HD patients...
March 28, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29606268/-incremental-haemodialysis
#14
Cécile Courivaud
The majority of incidental haemodialysis patients are systematically treated at the rate of three sessions per week, regardless of their level of residual kidney function. Incremental haemodialysis is a therapeutic strategy adapted to the residual kidney function level of each patient, to offer patients only the "dialysis dose" needed to supplement their residual kidney function, while ensuring that they achieve the objective of total clearance (renal+per-HD) recommended (weekly Standard Kt/V urea>2...
April 2018: Néphrologie & Thérapeutique
https://www.readbyqxmd.com/read/29590459/systemic-haemodynamics-in-haemodialysis-intradialytic-changes-and-prognostic-significance
#15
Stefanie Haag, Björn Friedrich, Andreas Peter, Hans-Ulrich Häring, Nils Heyne, Ferruh Artunc
Background: Although haemodialysis (HD) leads to alterations of systemic haemodynamics that can be monitored using dilution methods, there is a lack of data on the diagnostic and prognostic significance of haemodynamic monitoring during routine HD. Methods: In this multicentre study, we measured cardiac index (CI), access flow (AF) and central blood volume index (CBVI) during a single HD session in stable HD patients (n = 215) using the Transonic HD03 monitor (Transonic, Ithaca, NY, USA)...
March 26, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29587650/biopsy-proven-vancomycin-induced-acute-kidney-injury-a-case-report-and-literature-review
#16
Anri Sawada, Kunio Kawanishi, Shohei Morikawa, Toshihiro Nakano, Mio Kodama, Mitihiro Mitobe, Sekiko Taneda, Junki Koike, Mamiko Ohara, Yoji Nagashima, Kosaku Nitta, Takahiro Mochizuki
BACKGROUND: Vancomycin is the first-line antibiotic for methicillin-resistant Staphylococcus aureus and coagulase-negative strains. The risk of vancomycin-induced acute kidney injury increases with plasma vancomycin levels. Vancomycin-induced acute kidney injury is histologically characterized by acute interstitial nephritis and/or acute tubular necrosis. However, only 12 biopsy-proven cases of vancomycin-induced acute kidney injury have been reported so far, as renal biopsy is rarely performed for such cases...
March 27, 2018: BMC Nephrology
https://www.readbyqxmd.com/read/29587579/the-forearm-basilic-vein-looped-transposition-fistula-as-a-tertiary-option-for-upper-limb-vascular-access
#17
Maciej Zielinski, Nicholas Inston, Zbigniew Krasinski, Marcin Gabriel, Grzegorz Oszkinis
INTRODUCTION: The forearm basilic vein can serve as an option for haemodialysis access but may not be possible in cases where the wrist arteries are unsuitable. In this setting, the forearm basilic vein can be used in a looped transposition with a brachial artery anastomosis. AIMS: The aims of this study were to assess the outcome of forearm basilic vein looped transposition as an option for vascular access. MATERIAL AND METHODS: Data from January 2007 to December 2010 were prospectively collected and analysed...
March 1, 2018: Journal of Vascular Access
https://www.readbyqxmd.com/read/29582126/endovascular-treatment-of-haemodialysis-arteriovenous-fistula-with-drug-coated-balloon-angioplasty-a-single-centre-study
#18
Jernej Lučev, Silva Breznik, Dejan Dinevski, Robert Ekart, Mitja Rupreht
PURPOSE: To evaluate the effect of percutaneous transluminal angioplasty (PTA) on haemodialysis fistulas utilising drug-coated balloons with plain balloon vessel preparation (DCB). MATERIALS AND METHODS: In the study group, 31 patients (16 men; mean age 62.8 ± 17.2 years) with failing arteriovenous fistulas were treated, with DCB, and compared with a control group (31 patients; 15 men; mean age 67.0 ± 8.44 years), in which only plain balloon PTA was performed...
March 26, 2018: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/29579214/temocillin-dosing-in-haemodialysis-patients-based-on-population-pharmacokinetics-of-total-and-unbound-concentrations-and-monte-carlo-simulations
#19
Ana C Miranda Bastos, Stefaan J Vandecasteele, Anne Spinewine, Paul M Tulkens, Françoise Van Bambeke
Objectives: To develop a population model describing temocillin pharmacokinetics (PK) in patients undergoing haemodialysis and investigate how pharmacokinetic/pharmacodynamic (PD) targets can be met with different dosage regimens. Patients and methods: Sixteen patients received the currently licenced dosing of 1, 2 or 3 g of temocillin (total of 61 doses) corresponding to an inter-dialytic period of 20, 44 or 68 h, respectively, and a dialysis period of 4 h...
March 22, 2018: Journal of Antimicrobial Chemotherapy
https://www.readbyqxmd.com/read/29570911/methodological-challenges-to-collecting-clinical-and-economic-outcome-data-lessons-from-the-pilot-dialysis-outcomes-india-study
#20
Abhinav Bassi, Oommen John, Martin Gallagher, Sradha Kotwal, Rohina Joshi, Beverley Essue, Stephen Jan, Raja Ramachandran, Vijay Kher, John Knight, Vivekanand Jha
INTRODUCTION: Contemporary data on clinical and economic outcomes and quality of care amongst dialysis patients in India are not available. This pilot prospective study evaluated the feasibility of data collection and follow up within routine dialysis practice to inform setting up a dialysis registry. METHODS: An electronic instrument was developed to collect information on clinical and socio-demographic characteristics, outcome and out-of-pocket expenditure on incident patients commencing haemodialysis (HD) at two centres...
March 23, 2018: Nephrology
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