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https://www.readbyqxmd.com/read/28421377/vep-and-perg-in-patients-with-multiple-sclerosis-with-and-without-a-history-of-optic-neuritis
#1
M Janáky, Á Jánossy, G Horváth, G Benedek, G Braunitzer
PURPOSE: Visual electrophysiology is routinely used to detect the visual complications of multiple sclerosis, but the analysis mostly focuses on visual evoked potential (VEP) and especially the P100 component. Our goal was to analyze the components and waveform alterations of VEPs and pattern electroretinograms (PERGs) in patients with multiple sclerosis (MS) with good vision. METHODS: The main VEP and PERG components of 85 patients with MS were analyzed in two groups: 38 patients who had optic neuritis in their history (ON group) and 47 patients who had never had optic neuritis (MS group)...
April 18, 2017: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/28408638/blindfolding-during-wakefulness-causes-decrease-in-sleep-slow-wave-activity
#2
Eva Magdalena Korf, Matthias Mölle, Jan Born, Hong-Viet V Ngo
Slow wave activity (SWA, 0.5-4 Hz) represents the predominant EEG oscillatory activity during slow wave sleep (SWS). Its amplitude is considered in part a reflection of synaptic potentiation in cortical networks due to encoding of information during prior waking, with higher amplitude indicating stronger potentiation. Previous studies showed that increasing and diminishing specific motor behaviors produced corresponding changes in SWA in the respective motor cortical areas during subsequent SWS Here, we tested whether this relationship can be generalized to the visual system, that is, whether diminishing encoding of visual information likewise leads to a localized decrease in SWA over the visual cortex...
April 2017: Physiological Reports
https://www.readbyqxmd.com/read/28393030/surgical-treatment-and-visual-outcomes-of-cataract-with-persistent-hyperplastic-primary-vitreous
#3
Li Li, Da-Bei Fan, Ya-Ting Zhao, Yun Li, Fang-Fei Cai, Guang-Ying Zheng
AIM: To evaluate the surgical treatment and visual outcomes of eyes with cataract and persistent hyperplastic primary vitreous (PHPV). METHODS: This retrospective study included patients with cataract and PHPV treated with various strategies. Anterior PHPV was treated using phacoemulsification with underwater electric coagulation on posterior capsule neovascularization, posterior capsulotomy, anterior vitrectomy, and intraocular lens (IOL) implantation. Posterior PHPV was treated with lensectomy, posterior vitrectomy, retinal photocoagulation, and IOL implantation or silicone oil tamponade...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28369421/searching-for-biomarkers-of-cdkl5-disorder-early-onset-visual-impairment-in-cdkl5-mutant-mice
#4
Raffaele Mazziotti, Leonardo Lupori, Giulia Sagona, Mariangela Gennaro, Grazia Della Sala, Elena Putignano, Tommaso Pizzorusso
CDKL5 disorder is a neurodevelopmental disorder still without a cure. Murine models of CDKL5 disorder have been recently generated raising the possibility of preclinical testing of treatments. However, unbiased, quantitative biomarkers of high translational value to monitor brain function are still missing. Moreover, the analysis of treatment is hindered by the challenge of repeatedly and noninvasively testing neuronal function.We analyzed the development of visual responses in a mouse model of CDKL5 disorder to introduce visually evoked responses as a quantitative method to assess cortical circuit function...
March 28, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28367282/intraoperative-monitoring-of-flash-visual-evoked-potential-under-general-anesthesia
#5
Hironobu Hayashi, Masahiko Kawaguchi
In neurosurgical procedures that may cause visual impairment in the intraoperative period, the monitoring of flash visual evoked potential (VEP) is clinically used to evaluate visual function. Patients are unconscious during surgery under general anesthesia, making flash VEP monitoring useful as it can objectively evaluate visual function. The flash stimulus input to the retina is transmitted to the optic nerve, optic chiasm, optic tract, lateral geniculate body, optic radiation (geniculocalcarine tract), and visual cortical area, and the VEP waveform is recorded from the occipital region...
April 2017: Korean Journal of Anesthesiology
https://www.readbyqxmd.com/read/28361176/electrophysiological-assessment-for-early-detection-of-retinal-dysfunction-in-%C3%AE-thalassemia-major-patients
#6
Maria Dettoraki, Antonis Kattamis, Ioannis Ladas, Konstantinos Maragkos, Chryssanthi Koutsandrea, Klio Chatzistefanou, Konstantinos Laios, Dimitrios Brouzas, Marilita M Moschos
PURPOSE: The purpose of this study was to assess the role of various diagnostic tests in early detection of retinal changes in β-thalassemia major patients. METHODS: Thirty-eight visually asymptomatic β-thalassemia major patients receiving regular blood transfusions and iron-chelation therapy with deferoxamine (group A, n = 13), deferasirox (group B, n = 11) or deferoxamine with deferiprone (group C, n = 14) and fourteen age- and sex- matched healthy individuals were included in the study...
March 30, 2017: Graefe's Archive for Clinical and Experimental Ophthalmology
https://www.readbyqxmd.com/read/28355737/-clinical-features-and-prognostic-analysis-of-neuromyelitisoptica-spectrum-disease-with-sjogrensyndrome
#7
N Jia, Y Jing, Q C Li, L Liu, J W Wang, X M Hu
Objective: To explore the clinical features and conduct prognostic analysis about visual recovery and relapse of neuromyelitisoptica (NMO) spectrum disease (NMOSD) with sjogren syndrome (SS). Methods: A retrospective and prospective observational study was conducted.Between July 2013 and June 2016, 172 patients with NMOSD (NMOSD-non SS: 116/172, 67.4%; NMOSD-SS: 56/172, 32.6%) were assessed at Beijing Tongren Hospital, Capital Medical University, Beijing, China.The prognostic factors of NMOSD-SS patients were also analyzed...
March 21, 2017: Zhonghua Yi Xue za Zhi [Chinese medical journal]
https://www.readbyqxmd.com/read/28343723/-the-search-for-electrophysiological-predictors-of-visual-comfort-after-presbyopia-correction-with-contact-lenses
#8
A El Ameen, S Majzoub, P-J Pisella
Starting at 40 years of age, prespyopia affects a quarter of the world population. Many techniques of presbyopia surgery have emerged in recent years. The purpose of this study was to compare monovision and multifocality and to identify clinical and electrophysiological predictive markers of visual comfort for each correction available in clinical practice. Ten presbyopic patients participated in this study. Patients received monovision and multifocal correction using contact lenses for three weeks each in a random order...
April 2017: Journal Français D'ophtalmologie
https://www.readbyqxmd.com/read/28343188/multimodal-evoked-potentials-in-patients-with-multiple-sclerosis-in-assessment-of-the-course-of-the-disease
#9
Beata Łabuz-Roszak, Magdalena Torbus, Katarzyna Kubicka-Bączyk, Agnieszka Machowska-Majchrzak, Agata Kierber, Katarzyna Borucka, Małgorzata Zellner, Anna Starostak-Tatar, Krystyna Pierzchała
INTRODUCTION: Multiple sclerosis (MS) is a chronic inflammatory, demyelinating disease of the central nervous system with a multifocal damage. THE AIM: The assessment of the MS course by multimodal evoked potentials (EP). MATERIAL AND METHODS: We evaluated 95 patients (63 female, 32 male) with relapsing-remitting MS in the average age of 36.4±10.4. The average disease duration was 4.6±7.4 year. Among them, 48 patients (50.5%) were treated with immunomodulatory drugs...
2017: Wiadomości Lekarskie: Organ Polskiego Towarzystwa Lekarskiego
https://www.readbyqxmd.com/read/28336195/cognitive-correlates-of-visual-neural-plasticity-in-schizophrenia
#10
Carol Jahshan, Jonathan K Wynn, Daniel H Mathalon, Michael F Green
Neuroplasticity may be an important treatment target to improve the cognitive deficits in schizophrenia (SZ). Yet, it is poorly understood and difficult to assess. Recently, a visual high-frequency stimulation (HFS) paradigm that potentiates electroencephalography (EEG)-based visual evoked potentials (VEP) has been developed to assess neural plasticity in the visual cortex. Using this paradigm, we examined visual plasticity in SZ patients (N=64) and its correlations with clinical symptoms, neurocognition, functional capacity, and community functioning...
March 20, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28327351/parkinson-s-patients-can-rely-on-perspective-cues-to-perceive-3d-space
#11
Alexandra Séverac Cauquil, Fabienne Ory-Magne, Vincent Jardiné, Monique Galitzky, Maxime Rosito, Christine Brefel-Courbon, Simona Celebrini
3D perception, which is necessary for an optimal navigation in our environment, relies on 2 complementary kinds of cues; binocular cues allowing precise depth localization near the point of visual interest and monocular ones that are necessary for correct global perception of visual space. Recent studies described deficient binocular 3D vision in PD patients; here we tested 3D vision in PD patients when based on monocular cues (m3D). Sixteen PD patients and 16 controls had to categorize visual stimuli as perceived in 2D (flat) or 3D (with depth)...
March 18, 2017: Brain Research
https://www.readbyqxmd.com/read/28324945/a-comparative-study-of-pseudorandom-sequences-used-in-a-c-vep-based-bci-for-online-wheelchair-control
#12
Jonas Isaksen, Ali Mohebbi, Sadasivan Puthusserypady
In this study, a c-VEP based BCI system was developed to run on three distinctive pseudorandom sequences, namely the m-code, the Gold-code, and the Barker-code. The Visual Evoked Potentials (VEPs) were provoked using these codes. In the online session, subjects controlled a LEGO(®) Mindstorms(®) robot around a fixed track. Choosing the optimal code proved a significant increase in accuracy (p<;0.00001) over the average performance. No single code proved significantly more accurate than the others (p=0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28291207/-functional-examinations-of-visual-channels-physiological-basis
#13
M V Zueva, I V Tsapenko, E P Lantukh, N M Maglakelidze
In this paper, technical details of visual evoked potentials (VEP) assessment and pattern electroretinography (PERG) are reviewed. Both methods are used to perform an objective functional examination of visual channels and to clarify the level, at which they have been damaged. Contributions of parvo- (P), magno- (M) and koniocellular (K) systems to the morphology of PERG and VEP responses are discussed with account to test conditions, selectively supportive of the activity of particular cell populations. The review analyzes the physiological role of such stimulation parameters as brightness and color contrast of the pattern elements as well as spatial and temporal frequency in detecting dysfunction of color channels and mistuning of the P- and M- pathways...
2017: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/28283099/sensitivity-of-visual-evoked-potentials-and-spectral-domain-optical-coherence-tomography-in-early-relapsing-remitting-multiple-sclerosis
#14
COMPARATIVE STUDY
Raed Behbehani, Samar Ahmed, Jasem Al-Hashel, Rossen T Rousseff, Raed Alroughani
BACKGROUND: Visual evoked potentials and spectral-domain optical coherence tomography are common ancillary studies that assess the visual pathways from a functional and structural aspect, respectively. OBJECTIVE: To compare prevalence of abnormalities of Visual evoked potentials (VEP) and spectral-domain optical coherence tomography (SDOCT) in patients with relapsing remitting multiple sclerosis (RRMS). METHODS: A cross-sectional study of 100 eyes with disease duration of less than 5 years since the diagnosis...
February 2017: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/28281303/long-chain-polyunsaturated-fatty-acid-supplementation-in-infants-born-at-term
#15
REVIEW
Bonny Jasani, Karen Simmer, Sanjay K Patole, Shripada C Rao
BACKGROUND: The long chain polyunsaturated fatty acids (LCPUFA) docosahexaenoic acid (DHA) and arachidonic acid (AA) are considered essential for maturation of the developing brain, retina and other organs in newborn infants. Standard infant milk formulae are not supplemented with LCPUFA; they contain only alpha-linolenic acid and linoleic acid, from which formula-fed infants must synthesise their own DHA and AA, respectively. Over the past few years, some manufacturers have added LCPUFA to formula milk and have marketed these products as providing an advantage for the overall development of full-term infants...
March 10, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28268607/neural-decoding-of-code-modulated-visual-evoked-potentials-by-spatio-temporal-inverse-filtering-for-brain-computer-interfaces
#16
Jun-Ichi Sato, Yoshikazu Washizawa
This study addresses neural decoding of a code modulated visual evoked potentials (c-VEPs). c-VEP was recently developed, and applied to brain computer interfaces (BCIs). c-VEP BCI exhibits faster communication speed than existing VEP-based BCIs. In c-VEP BCI, the canonical correlation analysis (CCA) that maximizes the correlation between an averaged signal and single trial signals is often used for the spatial filter. However, CCA does not utilize information of given PN sequence, and hence, the filtered signal may not have properties of PN sequence...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
https://www.readbyqxmd.com/read/28251085/short-duration-transient-visual-evoked-potentials-and-color-reflectivity-discretization-analysis-in-glaucoma-patients-and-suspects
#17
Michael Waisbourd, Rebekah H Gensure, Ardalan Aminlari, Sonya B Shah, Nitasha Khanna, Neil Sood, Jeanne Molineaux, Alberto Gonzalez, Jonathan S Myers, L Jay Katz
AIM: To evaluate the use of short-duration transient visual evoked potentials (VEP) and color reflectivity discretization analysis (CORDA) in glaucomatous eyes, eyes suspected of having glaucoma, and healthy eyes. METHODS: The study included 136 eyes from 136 subjects: 49 eyes with glaucoma, 45 glaucoma suspect eyes, and 42 healthy eyes. Subjects underwent Humphrey visual field (VF) testing, VEP testing, as well as peripapillary retinal nerve fiber layer optical coherence tomography imaging studies with post-acquisition CORDA applied...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28245274/visual-steady-state-in-relation-to-age-and-cognitive-function
#18
Anna Horwitz, Mia Dyhr Thomsen, Iris Wiegand, Henrik Horwitz, Marc Klemp, Miki Nikolic, Lene Rask, Martin Lauritzen, Krisztina Benedek
Neocortical gamma activity is crucial for sensory perception and cognition. This study examines the value of using non-task stimulation-induced EEG oscillations to predict cognitive status in a birth cohort of healthy Danish males (Metropolit) with varying cognitive ability. In particular, we examine the steady-state VEP power response (SSVEP-PR) in the alpha (8Hz) and gamma (36Hz) bands in 54 males (avg. age: 62.0 years) and compare these with 10 young healthy participants (avg. age 27.6 years). Furthermore, we correlate the individual alpha-to-gamma difference in relative visual-area power (ΔRV) with cognitive scores for the older adults...
2017: PloS One
https://www.readbyqxmd.com/read/28229892/safety-and-efficacy-of-opicinumab-in-acute-optic-neuritis-renew-a-randomised-placebo-controlled-phase-2-trial
#19
Diego Cadavid, Laura Balcer, Steven Galetta, Orhan Aktas, Tjalf Ziemssen, Ludo Vanopdenbosch, Jette Frederiksen, Mark Skeen, Glenn J Jaffe, Helmut Butzkueven, Focke Ziemssen, Luca Massacesi, Yi Chai, Lei Xu, Stefanie Freeman
BACKGROUND: The human monoclonal antibody opicinumab (BIIB033, anti-LINGO-1) has shown remyelinating activity in preclinical studies. We therefore assessed the safety and tolerability, and efficacy of opicinumab given soon after a first acute optic neuritis episode. METHODS: This randomised, double-blind, placebo-controlled, phase 2 study (RENEW) was done at 33 sites in Australia, Canada, and Europe in participants (aged 18-55 years) with a first unilateral acute optic neuritis episode within 28 days from study baseline...
March 2017: Lancet Neurology
https://www.readbyqxmd.com/read/28226793/a-comparative-study-of-pseudorandom-sequences-used-in-a-c-vep-based-bci-for-online-wheelchair-control
#20
Jonas Isaksen, Ali Mohebbi, Sadasivan Puthusserypady, Jonas Isaksen, Ali Mohebbi, Sadasivan Puthusserypady, Jonas Isaksen, Sadasivan Puthusserypady, Ali Mohebbi
In this study, a c-VEP based BCI system was developed to run on three distinctive pseudorandom sequences, namely the m-code, the Gold-code, and the Barker-code. The Visual Evoked Potentials (VEPs) were provoked using these codes. In the online session, subjects controlled a LEGO(®) Mindstorms(®) robot around a fixed track. Choosing the optimal code proved a significant increase in accuracy (p<;0.00001) over the average performance. No single code proved significantly more accurate than the others (p=0...
August 2016: Conference Proceedings: Annual International Conference of the IEEE Engineering in Medicine and Biology Society
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