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https://www.readbyqxmd.com/read/27922231/evaluation-of-central-nervous-system-in-patients-with-glycogen-storage-disease-type-1a
#1
Yusuf Aydemir, Figen Gürakan, İnci Nur Saltık Temizel, Hülya Demir, Kader Karlı Oğuz, Dilek Yalnızoğlu, Meral Topçu, Hasan Özen, Aysel Yüce
We aimed to evaluate structure and functions of central nervous system (CNS) in children with glycogen storage disease (GSD) type 1a. Neurological examination, psychometric tests, electroencephalography (EEG), magnetic resonance imaging (MRI), visual evoked potentials (VEP) and brainstem auditory evoked potentials (BAEP) were performed. The results were compared between patients with good and poor metabolic control and healthy children. Twenty-three patients with GSD type 1a were studied. Twelve patients were in poor metabolic control group and 11 patients in good metabolic control group...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27919490/quantitative-visual-tests-after-poorly-recovered-optic-neuritis-due-to-multiple-sclerosis
#2
Erin E Longbrake, Samantha Lancia, Nhial Tutlam, Kathryn Trinkaus, Robert T Naismith
BACKGROUND: Visual dysfunction in MS can be quantified using a variety of tests. Many vision tests have not been formally evaluated among MS patients with existing visual dysfunction. OBJECTIVE: Evaluate several versions of visual acuity and contrast sensitivity tests, measures of central and peripheral vision, retina structure, electrophysiologic function, and quality of life among MS patients with moderate/severe visual dysfunction. METHODS: Cross-sectional study of 46 patients with stable, incompletely recovered optic neuritis...
November 2016: Multiple Sclerosis and related Disorders
https://www.readbyqxmd.com/read/27910862/methylphenidate-enhances-early-stage-sensory-processing-and-rodent-performance-of-a-visual-signal-detection-task
#3
Rachel L Navarra, Brian D Clark, Andrew T Gargiulo, Barry D Waterhouse
Methylphenidate (MPH) is used clinically to treat attention-deficit/hyperactivity disorder (ADHD) and off-label as a performance enhancing agent in healthy individuals. MPH enhances catecholamine transmission via blockade of norepinephrine (NE) and dopamine (DA) reuptake transporters. However, it is not clear how this action impacts neural circuits performing cognitive and sensorimotor functions driving performance enhancement. The dorsal lateral geniculate nucleus (dLGN) is the primary thalamic relay for visual information from the retina to the cortex and is densely innervated by NE-containing fibers from the locus coeruleus (LC), a pathway known to modulate state-dependent sensory processing...
December 2, 2016: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/27882486/vep-analysis-methods-in-children-with-optic-nerve-hypoplasia-relationship-to-visual-acuity-and-optic-disc-diameter
#4
John P Kelly, James O Phillips, Avery H Weiss
PURPOSE: Assessing vision in young children with optic nerve hypoplasia (ONH) is challenging due to multi-directional infantile nystagmus, the range of optic nerve loss, and cognitive delay. This study examined visual evoked potential (VEP) responses and averaging techniques in children with ONH. The assumption is that EEG epochs with inconsistent temporal phase would be associated with nystagmus, signal reduction due to axon loss, and visual inattention. METHODS: A retrospective chart review was performed on 44 children (average age 2...
November 23, 2016: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27874946/visual-and-somotosensory-evoked-potentials-in-asymptomatic-patients-with-vitamin-b12-deficiency
#5
B Gökçe Çokal, H N Güneş, S K Güler, T K Yoldaş
OBJECTIVE: Vitamin B12 deficiency may be asymptomatic or present with a wide range of neurological and hematological disorders. Our aim in this study is to evaluate visual (VEP) and somatosensory evoked potential (SEP) parameters in patients with vitamin B12 deficiency who had no clinical evidence of visual impairment or neurological syndrome findings and compare the findings with healthy controls to determine whether there is a correlation between VEP and SEP parameters and serum vitamin B12 levels...
November 2016: European Review for Medical and Pharmacological Sciences
https://www.readbyqxmd.com/read/27864655/imitating-the-effect-of-amblyopia-on-vep-based-acuity-estimates
#6
Sven P Heinrich, Celia M Bock, Michael Bach
PURPOSE: Acuity testing based on visual evoked potentials (VEPs) overestimates acuity in patients with amblyopia. We hypothesized that distortion and fragmentation of the stimulus in amblyopia impede recognition of optotypes, while it leaves the pattern onset response in the VEP mostly unaffected, resulting in overestimation of acuity. METHODS: Acuity VEPs were recorded in visually normal participants with the stimulus degraded by patterned polymethyl methacrylate panes, which induce distortion and fragmentation...
November 18, 2016: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27862474/steady-state-vep-responses-to-uncomfortable-stimuli
#7
Louise O'Hare
Periodic stimuli, such as op-art, can evoke a range of aversive sensations included in the term visual discomfort. Illusory motion effects are elicited by fixational eye movements, but the cortex might also contribute to effects of discomfort. To investigate this possibility, steady-state visually-evoked responses (SSVEPs) to contrast-matched op-art-based stimuli were measured at the same time as discomfort judgements. On average, discomfort reduced with increasing spatial frequency of the pattern. By contrast, the peak amplitude of the SSVEP response was around the midrange spatial frequencies...
November 15, 2016: European Journal of Neuroscience
https://www.readbyqxmd.com/read/27858722/defective-chromatic-and-achromatic-visual-pathways-in-developmental-dyslexia-cues-for-an-integrated-intervention-programme
#8
Luca Bonfiglio, Tommaso Bocci, Fabrizio Minichilli, Alessandra Crecchi, Davide Barloscio, Donata Maria Spina, Bruno Rossi, Ferdinando Sartucci
PURPOSE: As well as obtaining confirmation of the magnocellular system involvement in Developmental dyslexia (DD); the aim was primarily to search for a possible involvement of the parvocellular system; and, furthermore, to complete the assessment of the visual chromatic axis by also analysing the koniocellular system. METHODS: Visual evoked potentials (VEPs) in response to achromatic stimuli with low luminance contrast and low spatial frequency, and isoluminant red/green and blue/yellow stimuli with high spatial frequency were recorded in 10 dyslexic children and 10 age- and sex-matched, healthy subjects...
November 16, 2016: Restorative Neurology and Neuroscience
https://www.readbyqxmd.com/read/27845150/the-extraction-of-motion-onset-vep-bci-features-based-on-deep-learning-and-compressed-sensing
#9
Teng Ma, Hui Li, Hao Yang, Xulin Lv, Peiyang Li, Tiejun Liu, Dezhong Yao, Peng Xu
BACKGROUND: Motion-onset visual evoked potentials (mVEP) can provide a softer stimulus with reduced fatigue, and it has potential applications for brain computer interface(BCI)systems. However, the mVEP waveform is seriously masked in the strong background EEG activities, and an effective approach is needed to extract the corresponding mVEP features to perform task recognition for BCI control. NEW METHOD: In the current study, we combine deep learning with compressed sensing to mine discriminative mVEP information to improve the mVEP BCI performance...
November 11, 2016: Journal of Neuroscience Methods
https://www.readbyqxmd.com/read/27843702/to-see-or-not-to-see-the-ability-of-the-magno-and-parvocellular-response-to-manifest-itself-in-the-vep-determines-its-appearance-to-a-pattern-reversing-and-pattern-onset-stimulus
#10
Valentine L Marcar, Lutz Jäncke
INTRODUCTION: The relationship between stimulus property, brain activity, and the VEP is still a matter of uncertainty. METHOD: We recorded the VEP of 43 volunteers when viewing a series of dartboard images presented as both a pattern reversing and pattern onset/offset stimulus. Across the dartboard images, the total stimulus area undergoing a luminance contrast change was varied in a graded manner. RESULTS: We confirmed the presence of two independent neural processing stages...
November 2016: Brain and Behavior
https://www.readbyqxmd.com/read/27833058/basophil-mediated-pro-allergic-inflammation-in-vehicle-emitted-particles-exposure
#11
Alexander M Zakharenko, Ayse Basak Engin, Valery V Chernyshev, Vladimir V Chaika, Sergey M Ugay, Ramin Rezaee, Gholamreza Karimi, Vladimir A Drozd, Anna V Nikitina, Sergey F Solomennik, Olga R Kudryavkina, Liu Xin, Yuan Wenpeng, Manolis Tzatzarakis, Aristidis M Tsatsakis, Kirill S Golokhvast
Despite of the fact that engine manufacturers develop a new technology to reduce exhaust emissions, insufficient attention given to particulate emissions. However, diesel exhaust particles are a major source of air-borne pollution, contain vast amount of polycyclic aromatic hydrocarbons (PAHs) and may have deleterious effects on the immune system, resulting in the induction and enhancement of pro-allergic processes. In the current study, vehicle emitted particles (VEP) from 2 different types of cars (diesel - D and gasoline - G) and locomotive (L) were collected...
January 2017: Environmental Research
https://www.readbyqxmd.com/read/27832406/electrophysiological-testing-of-visual-function-after-mirror-telescope-implantation-a-case-report
#12
Jan Kremláček, Naďa Jirásková, Jana Nekolová, Radovan Šikl, Miroslav Kuba
PURPOSE: The implantation of an intraocular telescope increases life quality in patients with end-stage age-related macular degeneration (AMD). The present study monitored changes in electrophysiological markers of visual processing before and during seventeen months after a novel mirror telescope implantation in two patients (OV-male 90 years, MZ-female 70 years) with the final-stage form of AMD. METHODS: Visual evoked potentials were recorded to high-contrast pattern-reversal (PR-VEP for check size 40' and 10'), low-contrast motion-onset stimuli (in visual periphery M-VEP M20°, and in central part M-VEP C8°), and event-related potentials (ERPs) in the oddball visual paradigm...
November 10, 2016: Documenta Ophthalmologica. Advances in Ophthalmology
https://www.readbyqxmd.com/read/27821640/familial-history-of-migraine-influences-habituation-of-visual-evoked-potentials
#13
Marco Lisicki, Emiliano Ruiz-Romagnoli, Kevin D'Ostilio, Raúl Piedrabuena, Roberto Giobellina, Jean Schoenen, Delphine Magis
BACKGROUND: Lack of habituation of visual evoked potentials (VEP) is a common finding in migraine patients between attacks. Previous studies have suggested an electrophysiological familial aggregation pattern associated with migraine. The aim of this study was to evaluate the influence of a positive familial history of migraine on VEP amplitude and habituation. METHODS: We recorded six blocks of 100 VEP during continuous pattern-reversal stimulation in 30 patients with migraine between attacks (MO) and in 30 healthy volunteers, of whom 15 had a first-degree relative suffering from migraine (HVm) and 15 had not (HV)...
November 7, 2016: Cephalalgia: An International Journal of Headache
https://www.readbyqxmd.com/read/27820727/the-role-of-brain-angiotensin-ii-type-2-receptors-and-nitric-oxide-in-the-renal-sympathoinhibitory-response-to-acute-volume-expansion-in-conscious-rats
#14
Mohammed H Abdulla, Edward J Johns
OBJECTIVE: The study was performed to investigate the role of angiotensin II type 2 (AT2) receptors and nitric oxide in the renal sympathoinhibitory response to volume expansion (VEP). METHOD: Conscious rats were subjected to volume expansion (VEP) [0.25% body weight/min saline for 10 min intravenously (i.v.)] following intracerebroventricular (i.c.v.) infusion of either saline or angiotensin II (Ang II), or a combination of Ang II with either losartan, PD123319, or N-nitro-L-arginine methyl ester (L-NAME)...
November 4, 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27807541/single-trial-sparse-representation-based-approach-for-vep-extraction
#15
Nannan Yu, Funian Hu, Dexuan Zou, Qisheng Ding, Hanbing Lu
Sparse representation is a powerful tool in signal denoising, and visual evoked potentials (VEPs) have been proven to have strong sparsity over an appropriate dictionary. Inspired by this idea, we present in this paper a novel sparse representation-based approach to solving the VEP extraction problem. The extraction process is performed in three stages. First, instead of using the mixed signals containing the electroencephalogram (EEG) and VEPs, we utilise an EEG from a previous trial, which did not contain VEPs, to identify the parameters of the EEG autoregressive (AR) model...
2016: BioMed Research International
https://www.readbyqxmd.com/read/27760862/gender-effect-on-neuromyelitis-optica-spectrum-disorder-with-aquaporin4-immunoglobulin-g
#16
Sung-Min Kim, Patrick Waters, Mark Woodhall, Yoo-Jin Kim, Jin-Ah Kim, So Young Cheon, Sehoon Lee, Seong Rae Jo, Dong Gun Kim, Kyeong Cheon Jung, Kwang-Woo Lee, Jung-Joon Sung, Kyung Seok Park
BACKGROUND: Neuromyelitis optica spectrum disorder with aquaporin4-immunoglobulin G (NMOSD-AQP4) is an inflammatory disease characterised by a high female predominance. However, the effect of gender in patients with NMOSD-AQP4 has not been fully evaluated. OBJECTIVE: The aim of this study was to determine the effect of gender in clinical manifestations and prognosis of patients with NMOSD-AQP4. METHODS: The demographics, clinical and radiological characteristics, pattern reversal visual evoked potential (VEP) test results, and prognosis of 102 patients (18 males) with NMOSD-AQP4 were assessed...
October 19, 2016: Multiple Sclerosis: Clinical and Laboratory Research
https://www.readbyqxmd.com/read/27749933/afferent-visual-pathway-affection-in-patients-with-pmp22-deletion-related-hereditary-neuropathy-with-liability-to-pressure-palsies
#17
Alexander U Brandt, Elena Meinert-Bohn, Jan Leo Rinnenthal, Hanna Zimmermann, Janine Mikolajczak, Timm Oberwahrenbrock, Sebastian Papazoglou, Caspar F Pfüller, Johann Schinzel, Björn Tackenberg, Friedemann Paul, Katrin Hahn, Judith Bellmann-Strobl
BACKGROUND: The PMP22 gene encodes a protein integral to peripheral myelin. Its deletion leads to hereditary neuropathy with liability to pressure palsies (HNPP). PMP22 is not expressed in the adult central nervous system, but previous studies suggest a role in CNS myelin development. The objective of this study was to identify potential structural and functional alterations in the afferent visual system in HNPP patients. METHODS: Twenty HNPP patients and 18 matched healthy controls (HC) were recruited in a cross-sectional study...
2016: PloS One
https://www.readbyqxmd.com/read/27749593/evaluation-of-leber-s-hereditary-optic-neuropathy-patients-prior-to-a-gene-therapy-clinical-trial
#18
Shuo Yang, Hong Yang, Si-Qi Ma, Shuai-Shuai Wang, Heng He, Min-Jian Zhao, Bin Li
Gene therapy may be a promising approach for the treatment of Leber hereditary optic neuropathy. The aim of this study was to evaluate patients with this condition who were recruited into an upcoming gene therapy clinical trial and to assess any changes in the detection parameters to provide support for the clinical trial. Sixteen patients with Leber hereditary optic neuropathy were evaluated using visual function tests 12 months before the initiation of gene therapy. Then, the results of visual acuity (VA), visual field (VF), RNFL (retinal nerve fiber layer) thickness, and Pattern-reversal Visual evoked potential (PR-VEP) were compared and analyzed...
October 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27716799/rapid-and-objective-assessment-of-neural-function-in-autism-spectrum-disorder-using-transient-visual-evoked-potentials
#19
Paige M Siper, Vance Zemon, James Gordon, Julia George-Jones, Stacey Lurie, Jessica Zweifach, Teresa Tavassoli, A Ting Wang, Jesslyn Jamison, Joseph D Buxbaum, Alexander Kolevzon
OBJECTIVE: There is a critical need to identify biomarkers and objective outcome measures that can be used to understand underlying neural mechanisms in autism spectrum disorder (ASD). Visual evoked potentials (VEPs) offer a noninvasive technique to evaluate the functional integrity of neural mechanisms, specifically visual pathways, while probing for disease pathophysiology. METHODS: Transient VEPs (tVEPs) were obtained from 96 unmedicated children, including 37 children with ASD, 36 typically developing (TD) children, and 23 unaffected siblings (SIBS)...
2016: PloS One
https://www.readbyqxmd.com/read/27711139/dichoptic-metacontrast-masking-functions-to-infer-transmission-delay-in-optic-neuritis
#20
Maximilian Bruchmann, Catharina Korsukewitz, Julia Krämer, Heinz Wiendl, Sven G Meuth
Optic neuritis (ON) has detrimental effects on the transmission of neuronal signals generated at the earliest stages of visual information processing. The amount, as well as the speed of transmitted visual signals is impaired. Measurements of visual evoked potentials (VEP) are often implemented in clinical routine. However, the specificity of VEPs is limited because multiple cortical areas are involved in the generation of P1 potentials, including feedback signals from higher cortical areas. Here, we show that dichoptic metacontrast masking can be used to estimate the temporal delay caused by ON...
2016: PloS One
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