Read by QxMD icon Read


Caroline Carney, Michaela Benzeval
BACKGROUND: Grip strength in early adulthood and midlife is an important predictor of disability, morbidity and mortality in later life. Understanding social patterning in grip strength at different life stages could improve insight into inequalities in age-related decline and when in the life course interventions could prevent the emergence of inequalities. METHODS: Using United Kingdom Household Longitudinal Study (UKHLS) data on 19,292 people aged 16 to 99, fractional polynomial models were fitted to identify which function of age best described its association with grip strength...
March 21, 2018: BMC Public Health
Shirin Niromanesh, Mahboobeh Shirazi, Mitra Eftekhariyazdi, Forough Mortazavi
Background: Gestational diabetes mellitus (GDM) is one of the most common medical complications of pregnancy and is related to poor perinatal outcomes. Reduction of neonatal complications of GDM is feasible by assessment of fetal well-being. Both fetal Doppler and NST are used for the screening of high-risk pregnancies. Objective: We aimed to compare the non-stress test (NST) and umbilical artery (UA) Doppler assessments for evaluation of the adverse perinatal outcomes in GDM...
December 2017: Electronic Physician
J A Custodio-Mendoza, R A Lorenzo, I M Valente, P J Almeida, M A Lage, J A Rodrigues, A M Carro
A fast and effective method using a modified QuEChERS (Quick, Easy, Cheap, Effective, Rugged and Safe) approach which includes partitioned liquid-liquid extraction (PLLE) and dispersive solid phase extraction (dSPE) clean-up step for the determination of seven 3-monochloropropane-1,2-diol (3-MCPD) fatty acid diesters in vegetable oils is developed and validated according to the Food and Drug Administration (FDA) guidelines. Due to the complexity of the matrices, combination of silica based sorbents (Silica Strong Anion Exchange (Si-SAX), Supel™ QuE Z-Sep+ (Z-Sep+) and Primary Secondary Amine (PSA) were tested for lipid removal...
March 13, 2018: Journal of Chromatography. A
Cheryl I Anderson, Marc D Basson, Muhammad Ali, Alan T Davis, Robert L Osmer, Michael K McLeod, Pam S Haan, Robert G Molnar, Andi N Peshkepija, John C Hardaway, Karen A Chojnacki, Christopher C Pfeifer, Jeffrey M Gauvin, Mark W Jones, M Ashraf Mansour
BACKGROUND: It is increasingly important for faculty to teach deliberately and provide timely, detailed and formative feedback on surgical trainee performance. We initiated a multicenter study to improve resident evaluative processes and enhance teaching and learning behaviors while engaging residents in their education. METHODS: Faculty from seven U.S. postgraduate training programs rated resident operative performances using the perioperative briefing, intraoperative teaching, debriefing model (BID) and rated patient visits/academic performances using the entrustable professional activities (EPAs) model via a web-based platform...
March 15, 2018: Journal of the American College of Surgeons
Christopher S Jones, Sea-Won Kim, Thomas F Wilton, Keith E Schilling, Caroline A Davis
Real-time, continuous, in situ water quality sensors were deployed on a fourth-order Iowa (U.S.) stream draining an agricultural watershed to evaluate key in-stream processes affecting concentrations of nitrate during a 24-day late summer (Aug-Sep) period. Overall, nitrate-nitrogen (NO3 -N) concentrations declined 0.11 mg L-1  km-1 , or about 1.9% km-1 and 35% in total across 18 km. We also calculated stream metabolic rates using in situ dissolved oxygen data and determined stream biotic N demand to be 108-117 mg m-2  day-1 ...
March 17, 2018: Environmental Monitoring and Assessment
Antonella Macerollo, Matt J N Brown, James M Kilner, Robert Chen
Measurements of somatosensory evoked potentials (SEPs), recorded using electroencephalography during different phases of movement, have been fundamental in understanding the neurophysiological changes related to motor control. SEP recordings have also been used to investigate adaptive plasticity changes in somatosensory processing related to active and observational motor learning tasks. Combining noninvasive brain stimulation with SEP recordings and intracranial SEP depth recordings, including recordings from deep brain stimulation electrodes, has been critical in identifying neural areas involved in specific temporal stages of somatosensory processing...
March 14, 2018: Trends in Neurosciences
Hiroshi Chadani, Soichiro Usui, Oto Inoue, Takashi Kusayama, Shin-Ichiro Takashima, Takeshi Kato, Hisayoshi Murai, Hiroshi Furusho, Ayano Nomura, Hirofumi Misu, Toshinari Takamura, Shuichi Kaneko, Masayuki Takamura
Selenoprotein P (SeP), a liver-derived secretory protein, functions as a selenium supply protein in the body. SeP has been reported to be associated with insulin resistance in humans through serial analysis of gene expression. Recently, SeP has been found to inhibit vascular endothelial growth factor-stimulated cell proliferation in human umbilical vein endothelial cells, and impair angiogenesis in a mouse hind limb model. In this study, the role of SeP in ischemia/reperfusion (I/R) injury has been investigated...
March 16, 2018: International Journal of Molecular Sciences
Sean R Townsend, Lemeneh Tefera, Emanuel P Rivers
No abstract text is available yet for this article.
March 15, 2018: Annals of Internal Medicine
Dominique J Pepper, Charles Natanson, Peter Q Eichacker
No abstract text is available yet for this article.
March 15, 2018: Annals of Internal Medicine
Anisur Rahman, Mohammad Akbar Faqeerzada, Byoung-Kwan Cho
BACKGROUND: Allicin and soluble solid content (SSC) in garlic is the responsible for its pungent flavor and odor. However, current conventional methods such as high-pressure liquid chromatography (HPLC), refractometer has a critical drawbacks in that they are time-consuming, labor-intensive and destructive procedures. The present study aimed to predict the allicin and soluble solid content (SSC) in garlic using hyperspectral imaging in combination with variable selection algorithms and calibration models...
March 14, 2018: Journal of the Science of Food and Agriculture
Nancy E Epstein
Background: The risk of spinal cord injury (SCI) due to decreased cord perfusion following thoracic/thoracoabdominal aneurysm surgery (T/TL-AAA) and thoracic endovascular aneurysm repair (TEVAR) ranges up to 20%. For decades, therefore, many vascular surgeons have utilized cerebrospinal fluid drainage (CSFD) to decrease intraspinal pressure and increase blood flow to the spinal cord, thus reducing the risk of SCI/ischemia. Methods: Multiple studies previously recommend utilizing CSFD following T/TL-AAA/TEVAR surgery to treat SCI by increasing spinal cord blood flow...
2018: Surgical Neurology International
Z Sun, X Y Wu, C L Wu
HOTAIR has been reported to be associated with development and metastasis in different types of cancer. This meta- analysis collected all relevant articles and explored the correlation of HOTAIR with lymph node metastasis (LNM) and distant metastasis (DM). A literature collection was conducted by searching PubMed, Web of Science, Google Scholar and Cochrane Library (up to Sep 11, 2016). The odds ratio (OR) with 95% confidence interval (95% CI) was calculated to assess the association with strength. Nineteen studies were included in this study, with a total of 1874 patients...
2018: Neoplasma
Braulio Hernández-Godínez, Adrián Poblano, Herlinda Bonilla-Jaime, Marcela Artega-Silva, Stephanie Sánchez-Torres, Rodrigo Mondragón-Lozano, Alejandra Ibáñez-Contreras
BACKGROUND: Somatosensory evoked potentials (SEPs) make it possible to obtain functional data on the activity of somatosensory pathway. OBJECTIVE: To evaluate the ontogeny of electrical nerve conduction in male rhesus monkeys using SEPs in correlation with the development of the musculoskeletal system based on somatometry and musculoskeletal enzymes. METHODS: Somatosensory evoked potentials of the medial and tibial nerves were performed, and somatometric measurements were obtained: total length, arm and forearm length, and thigh and calf length...
March 13, 2018: Journal of Medical Primatology
Easter Joury, Eduardo Bernabe, Jennifer E Gallagher, Wagner Marcenes
Little is known about the burden and impact of orofacial pain in deprived areas, and whether it mediates the relationship between socio-economic position (SEP) and impacts on daily life. We analysed data from a representative sample of 2,168 adults, aged 16-65 years, from the East London Oral Health Inequality study. Participants completed a validated questionnaire on demographics, SEP (area deprivation), orofacial pain (by anatomical site) in the past month and impacts related to oral conditions on daily life...
March 12, 2018: Pain
Neng-Min Zhu, Yan-Sheng Xu, Lichun Dai, Yun-Fei Zhang, Guo-Quan Hu
Zerovalent iron (ZVI) is an environmental-friendly reactive reagent for recovering heavy metals. However, the detailed recovery mechanism remains unclear due to a lack of quantitative analysis of recovery products. Herein, microscale ZVI, nanoscale ZVI and Ni/Fe nanoparticles were used to recover Pb(II) in aqueous solution and a sequential extraction procedure (SEP) was applied to determine the formed lead species quantitatively. At high initial Pb(II) concentration (500 mg L-1 ), more than 99.5% of Pb(II) was immobilized by Ni/Fe and n-ZVI, whereas m-ZVI caused inferior recovery efficiency (<25%)...
March 6, 2018: Journal of Hazardous Materials
Louise J C J den Biggelaar, Simone J P M Eussen, Simone J S Sep, Andrea Mari, Ele Ferrannini, Marleen M van Greevenbroek, Carla J van der Kallen, Casper G Schalkwijk, Ilja C W Arts, Coen D A Stehouwer, Pieter C Dagnelie
PURPOSE: Type 2 diabetes mellitus (T2DM) is characterized by both impaired pancreatic β-cell function (BCF) and insulin resistance. In the etiology of T2DM, BCF basically determines whether a person with a certain degree of insulin resistance develops T2DM, as β-cells are able to compensatorily increase insulin secretion. The effects of dietary intake on BCF are largely unknown. Our study aim was to investigate whether dietary macronutrient intake predicts BCF. METHODS: Prospective data (median follow-up 7 years) of 303 individuals recruited from the CODAM study population (aged 40-70 years, 39% women) were analyzed...
March 10, 2018: European Journal of Nutrition
Gilles Defer, Florian Le Caignec, Sophie Fedrizzi, François Montastruc, Damien Chevanne, Jean-Jacques Parienti, Laure Peyro-Saint-Paul
BACKGROUND: The reporting of adverse drug reactions (ADR) by patients represents an interesting challenge in the field of pharmacovigilance, but the reporting system is not adequately implemented in France. In 2015, only 20 MS patients in France reported ADR due to first-line disease-modifying drugs (DMD), while more than 3000 patients were initiated on DMD. The aim of this study is to validate a proof-of-concept as to whether the use of a mobile application (App) increases ADR reporting among patients with relapsing-remitting multiple sclerosis (RR-MS) receiving DMD...
March 9, 2018: Trials
Alexandra Chung, Anna Peeters, Emma Gearon, Kathryn Backholer
Background: In high-income countries, children with a lower socio-economic position (SEP) are more likely to gain excess weight compared with children with a higher SEP. The extent to which children's consumption of discretionary food and drinks contributes to the development of these inequalities over childhood has not been examined. Methods: The study sample comprised 3190 children from the nationally representative Longitudinal Study of Australian Children. Linear and logistic regression models were fitted in accordance with the product of coefficients mediation method to determine the contribution of cumulative consumption of sweet drinks, discretionary hot foods, savoury snacks and sweet snacks from the first year of life, over a period of 10 years, on the relationship between SEP and children's body mass index (BMI) z-score at age 10-11 years...
March 4, 2018: International Journal of Epidemiology
Angelo Palmigiano, Angela Messina, Rosaria Ornella Bua, Rita Barone, Luisa Sturiale, Mario Zappia, Domenico Garozzo
In this chapter, we present the methodology currently applied in our laboratory for the structural elucidation of the cerebrospinal fluid (CSF) N-glycome. N-glycans are released from denatured carboxymethylated glycoproteins by digestion with peptide-N-glycosidase F (PNGase F) and purified using both C18 Sep-Pak® and porous graphitized carbon (PGC) HyperSep™ Hypercarb™ solid-phase extraction (SPE) cartridges. The glycan pool is subsequently permethylated to increase mass spectrometry sensitivity. Molecular assignments are performed through matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI TOF MS) analysis considering either the protein N-linked glycosylation pathway or MALDI TOF MS/MS data...
2018: Methods in Molecular Biology
Konstantina Kalogianni, Jan C de Munck, Guido Nolte, Alistair N Vardy, Frans C T van der Helm, Andreas Daffertshofer
BACKGROUND: The accuracy of source reconstruction depends on the spatial configuration of the neural sources underlying encephalographic signals, the temporal distance of the source activity, the level and structure of noise in the recordings, and - of course - on the employed inverse method. This plenitude of factors renders a definition of 'spatial resolution' of the electro-encephalogram (EEG) a challenge. NEW METHOD: A proper definition of spatial resolution requires a ground truth...
February 26, 2018: Journal of Neuroscience Methods
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"