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https://www.readbyqxmd.com/read/28734265/decreased-lung-function-with-mediation-of-blood-parameters-linked-to-e-waste-lead-and-cadmium-exposure-in-preschool-children
#1
Xiang Zeng, Xijin Xu, H Marike Boezen, Judith M Vonk, Weidong Wu, Xia Huo
Blood lead (Pb) and cadmium (Cd) levels have been associated with lower lung function in adults and smokers, but whether this also holds for children from electronic waste (e-waste) recycling areas is still unknown. To investigate the contribution of blood heavy metals and lung function levels, and the relationship among living area, the blood parameter levels, and the lung function levels, a total of 206 preschool children from Guiyu (exposed area), and Haojiang and Xiashan (reference areas) were recruited and required to undergo blood tests and lung function tests during the study period...
July 19, 2017: Environmental Pollution
https://www.readbyqxmd.com/read/28734241/entrapment-perceived-burdensomeness-and-thwarted-belongingness-as-predictors-of-suicide-ideation
#2
Thomas Forkmann, Tobias Teismann
The Integrated Motivational-Volitional (IMV) Model of suicide posits that perceived burdensomeness and thwarted belongingness moderate the association between perceptions of entrapment and suicide ideation. However, the proposed moderation is yet to be tested. Possible moderator effects were investigated in an online sample (N = 480; 74% female; Mage = 28.5, SDage = 11.1). Entrapment and perceived burdensomeness predicted suicide ideation. However, neither perceived burdensomeness nor thwarted belongingness moderated the association between entrapment and suicide ideation...
July 16, 2017: Psychiatry Research
https://www.readbyqxmd.com/read/28734198/length-of-stay-for-25-791-california-patients-found-incompetent-to-stand-trial
#3
Matthew Renner, Carol Newark, Bradley J Bartos, Richard McCleary, Nicholas Scurich
Referrals and admissions to state psychiatric hospitals of criminal defendants found Incompetent to Stand Trial (IST) are on the rise in the state of California and other parts of the country. Studies of treatment outcomes of this population have primarily focused on factors that determine competency and/or restorability. However, as IST patients place an increasing resource burden on state psychiatric hospital systems, other outcomes such as length of stay (LOS) are becoming increasingly important for practitioners and policy makers to understand...
July 6, 2017: Journal of Forensic and Legal Medicine
https://www.readbyqxmd.com/read/28734167/mindfulness-practice-moderates-the-relationship-between-craving-and-substance-use-in-a-clinical-sample
#4
Matthew C Enkema, Sarah Bowen
Relapse following treatment for substance use disorders is highly prevalent, and craving has been shown to be a primary predictor of relapse. Mindfulness-Based Relapse Prevention (MBRP) is a psychosocial aftercare program integrating mindfulness and cognitive-behavioral approaches, aimed at reducing the risk and severity of relapse. Results from a recent randomized clinical trial demonstrate enhanced remission resilience for MBRP participants versus both cognitive-behavioral and treatment-as-usual controls...
June 29, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28734131/changes-in-health-related-quality-of-life-in-older-candidates-waiting-for-kidney-transplantation
#5
Kjersti Lønning, Karsten Midtvedt, Tomm Bernklev, Cathrine Brunborg, Marit Helen Andersen, Nanna von der Lippe, Anna V Reisaeter, Pål-Dag Line, Anders Hartmann, Kristian Heldal
AIM: There is limited available knowledge regarding health-related quality of life (HRQoL) in older patients with chronic kidney disease. We aimed to describe HRQoL in renal transplant candidates 65 years or older at transplant acceptance, and during the first year on the waiting list.. METHODS: A nationwide prospective observational study in Norway was conducted. HRQoL was evaluated at baseline (wait listing) and after 6 and 12 months using the patient self-reported Kidney Disease and Quality of Life Short form version 1...
July 22, 2017: Nephrology
https://www.readbyqxmd.com/read/28732389/loss-of-sun2-promotes-the-progression-of-prostate-cancer-by-regulating-fatty-acid-oxidation
#6
Cheng Yajun, Ye Chen, Li Xiaosa, Wang Xiao, Chen Jia, Wang Zhong, Xu Bin
The role of Sun2 has been described by previous studies in various types of cancers, including breast cancer and lung cancer. However, its role and potential molecular mechanism in the progression of prostate cancer have not been fully elucidated. In the present study, we found that Sun2 expression was reduced in prostate cancer tissues compared with paired normal tissues, and that low expression of Sun2 was significantly correlated with Higher Gleason scores, postoperative T stage (pT), Lymph nodal invasion and Clinical pathological stages...
July 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732381/lymph-node-ratio-but-not-the-total-number-of-examined-lymph-nodes-or-lymph-node-metastasis-is-a-predictor-of-overall-survival-for-pancreatic-neuroendocrine-neoplasms-after-surgical-resection
#7
Peng Liu, Xianbin Zhang, Yuru Shang, Lili Lu, Fei Cao, Min Sun, Zhaohui Tang, Brigitte Vollmar, Peng Gong
AIM: To evaluate the prognostic significance of lymph node metastasis, extent of examined lymph nodes (ELNs) and lymph node ratio (LNR) for resected pancreatic neuroendocrine neoplasms (pNENs). MATERIALS AND METHODS: Surgically resected pNENs were assimilated from the Surveillance, Epidemiology, and End Results database. Kaplan-Meier and Cox proportional hazard models were used to examine the prognostic effect of clinicopathological characteristics on overall survival; Harrell's concordance index was performed to assess the prognostic accuracy of all independent prognostic factors; and the Spearman's rank correlation was used to assess the correlation between LNR and other clinicopathological characteristics...
July 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732376/risk-factors-associated-with-fatality-of-severe-fever-with-thrombocytopenia-syndrome-a-meta-analysis
#8
Yuxin Chen, Bei Jia, Yong Liu, Rui Huang, Junhao Chen, Chao Wu
Severe fever with thrombocytopenia syndrome is an emerging life-threatening infectious disease identified in 2009. Given high case-fatality rate among patients with severe fever with thrombocytopenia syndrome, identification of the risk factors at acute phase associated with fatality is crucial for treatment. Therefore, we aimed to meta-analytically evaluate risk factors of fatal clinical outcome of severe fever with thrombocytopenia syndrome. 238 fatal cases and 873 non-fatal cases from 12 studies were included in this meta-analysis...
July 11, 2017: Oncotarget
https://www.readbyqxmd.com/read/28732315/total-and-ionized-magnesium-testing-in-the-surgical-intensive-care-unit-opportunities-for-improved-laboratory-and-pharmacy-utilization
#9
Daniel Dante Yeh, Nalin Chokengarmwong, Yuchiao Chang, Liyang Yu, Colleen Arsenault, Joseph Rudolf, Elizabeth Lee-Lewandrowski, Kent Lewandrowski
PURPOSE: Ionized fraction (iMg) is the physiologically active form of magnesium (Mg); total Mg may not accurately reflect iMg status. Erroneously "low" Mg levels may result in unnecessary repetitive testing. MATERIALS AND METHODS: From 11/2015 to 01/2016, patients ordered for Mg from a pilot ICU also had iMg tested. Weighted kappa statistic was used to assess agreement between Mg categories (low, normal, high). Predictors of unnecessary repeated Mg testing and repletion using data were explored through logistic regression models using GEE techniques to account for repeated measurements in both bivariate and multivariable analyses...
July 11, 2017: Journal of Critical Care
https://www.readbyqxmd.com/read/28732261/predictors-of-disclosure-management-behavior-at-the-end-of-1-year-follow-up-in-korean-adults-with-newly-diagnosed-epilepsy
#10
Sang-Ahm Lee, Soon-Kee No, Hyungkook Park, Ok-Joon Kim, Jee-Hyun Kwon, Ji-Yeon Ryu, Sang-Moo Lee, Kwang-Deog Jo
PURPOSE: Epilepsy is a concealable stigmatizing condition. We investigated the factors predicting disclosure management behavior in Korean adults with newly diagnosed epilepsy. METHODS: This longitudinal multicenter study included Korean adults with newly diagnosed epilepsy. Using statistical analyses, we determined at the end of a 1-year follow-up whether Disclosure Management Scale (DMS) scores were predicted by demographic, clinical, and psychosocial variables, including felt stigma, stress coping style, personality traits, social support, and experienced discrimination from society...
July 18, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28732243/modeling-trait-depression-amplifies-the-effect-of-childbearing-on-postpartum-depression
#11
Kristen G Merkitch, Katherine G Jonas, Michael W O'Hara
BACKGROUND: The literature on the relative risk for depression in the postpartum period has largely focused on state (or episodic) depression, and has not addressed trait depression (a woman's general tendency to experience depressed mood). The present study evaluates the association between childbirth and depression in the postpartum period, taking into account the role of stable differences in women's vulnerability for depression across a 10-year span. METHODS: Data from the National Longitudinal Survey of Youth 1997 Cohort (N = 4385) were used...
July 13, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28732186/assessing-the-impact-of-surgeon-experience-on-urinary-continence-recovery-after-robot-assisted-radical-prostatectomy-results-of-four-high-volume-surgeons
#12
Nicola Fossati, Ettore Di Trapani, Giorgio Gandaglia, Paolo Dell'Oglio, Paolo Umari, Nicolò Maria Buffi, Giorgio Guazzoni, Alexander Mottrie, Franco Gaboardi, Francesco Montorsi, Alberto Briganti, Nazareno Suardi
PURPOSE: To test the impact of surgeon experience on urinary continence (UC) recovery after robot-assisted radical prostatectomy (RARP). MATERIALS AND METHODS: The study included 1477 consecutive patients treated with RARP by four surgeons between 2006 and 2014. UC recovery was defined as being completely dry over a 24-hour period at follow-up. Surgeon experience was coded as the total number of RARP performed by the surgeon before the patient's operation. Multivariable analysis tested the association between surgeon experience and UC recovery...
July 21, 2017: Journal of Endourology
https://www.readbyqxmd.com/read/28732143/ifnl4-rs368234815-and-rs117648444-variants-predict-off-treatment-hbsag-seroclearance-in-ifn-treated-hbeag-negative-chronic-hepatitis-b-patients
#13
Enrico Galmozzi, Floriana Facchetti, Glenda Grossi, Alessandro Loglio, Mauro Vigano, Giovanna Lunghi, Massimo Colombo, Pietro Lampertico
BACKGROUND AND AIM: Robust baseline predictors of interferon (IFN) response in HBeAg negative chronic hepatitis B (CHB) patients are not currently available. The recently described rs368234815 TT/ΔG dinucleotide and rs117648444 nonsynonymous P70S polymorphisms in IFN lambda 4 (IFNL4) gene, which are strongly associated with response to IFN in hepatitis C virus (HCV) infection, could be also useful in IFN treated CHB patients. Here we assessed whether IFNL4 rs368234815 and rs117648444 polymorphisms predict IFN induced HBsAg clearance in CHB patients...
July 21, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28732141/intraoperative-ultrasound-for-prediction-of-hepatocellular-carcinoma-biological-behavior-prospective-comparison-with-pathology
#14
Roberto Santambrogio, Claudia Cigala, Matteo Barabino, Marco Maggioni, Giovanna Scifo, Savino Bruno, Emanuela Bertolini, Enrico Opocher, Gaetano Bulfamante
BACKGROUND AND AIMS: Preoperative prediction of both microinvasive hepatocellular carcinoma and histological grade of hepatocellular carcinoma is pivotal to treatment planning and prognostication. Aim of the study was to evaluate whether some intraoperative ultrasound features correlate with both the presence of same histological patterns and differentiation grade of hepatocellular carcinoma on the histologic features of the primary resected tumor. METHODS: All patients with single, small hepatocellular carcinoma that underwent hepatic resection were included in this prospective double-blind study: the intraoperative ultrasound patterns of nodule were registered and compared with similar histological features...
July 21, 2017: Liver International: Official Journal of the International Association for the Study of the Liver
https://www.readbyqxmd.com/read/28732134/physical-functioning-pain-and-health-related-quality-of-life-in-adults-with-juvenile-idiopathic-arthritis-a-longitudinal-30-year-follow-up-study
#15
Anita Tollisen, Anne M Selvaag, Hanne A Aulie, Vibke Lilleby, Astrid Aasland, Anners Lerdal, Berit Flatø
OBJECTIVES: To describe physical functioning, pain, and health-related quality of life (HRQOL) in adults with Juvenile idiopathic arthritis (JIA), investigate changes over time, and identify predictors of poorer HRQOL after 30 years of disease duration. METHODS: Patients (N=176) clinically examined after 15 years were reassessed with the Health Assessment Questionnaire Disability Index (HAQ-DI), Visual Analogue Scale Pain (VAS pain) and Medical Outcome Study 36-item Short Form (SF-36) after 23 and 30 years...
July 21, 2017: Arthritis Care & Research
https://www.readbyqxmd.com/read/28732091/perfusion-of-surgical-cavity-wall-enhancement-in-early-post-treatment-mr-imaging-may-stratify-the-time-to-progression-in-glioblastoma
#16
Ji Eun Park, Kyoung Hwa Ryu, Ho Sung Kim, Hyo Won Kim, Woo Hyun Shim, Seung Chai Jung, Choong Gon Choi, Sang Joon Kim, Jeong Hoon Kim
OBJECTIVE: To determine if perfusion in surgical cavity wall enhancement (SCWE) obtained in early post-treatment MR imaging can stratify time-to-progression (TTP) in glioblastoma. MATERIALS AND METHODS: This study enrolled 60 glioblastoma patients with more than 5-mm-thick SCWEs as detected on contrast-enhanced MR imaging after concurrent chemoradiation therapy. Two independent readers categorized the shape and perfusion state of SCWEs as nodular or non-nodular and as having positive or negative perfusion compared with the contralateral grey matter on arterial spin labeling (ASL)...
2017: PloS One
https://www.readbyqxmd.com/read/28732090/incidence-predictors-and-severity-of-adverse-events-among-whole-blood-donors
#17
Hamdan Almutairi, Mahmoud Salam, Abdulaziz Alajlan, Faisal Wani, Bushra Al-Shammari, Khaled Al-Surimi
BACKGROUND: Adverse events have been reported post blood donation. Donors might refrain from donating again due to such events which lowers the blood supply in collection centers. AIM: This study measured the incidence, predictors and severity of adverse events among donors of a single whole blood unit at one of the largest donation centers in Saudi Arabia. METHODS: A retrospective cohort was conducted in 2015 to investigate the adverse events immediately post donation...
2017: PloS One
https://www.readbyqxmd.com/read/28732072/placental-peptides-metabolism-and-maternal-factors-as-predictors-of-risk-of-gestational-diabetes-in-pregnant-women-a-case-control-study
#18
Robert Amadu Ngala, Linda Ahenkorah Fondjo, Peter Gmagna, Frank Naku Ghartey, Martin Akilla Awe
BACKGROUND: Gestational diabetes is a risk factor for perinatal complications; include shoulder dystocia, birth injuries such as bone fractures and nerve palsies. It is associated with later development of type 2 diabetes, the risk of macrosomia and other long-term health effects of infants born to diabetic mothers. The study assesses placental peptides and maternal factors as potential predictors of gestational diabetes among pregnant women. MATERIAL AND METHODS: A total of 200 pregnant women were recruited for the study, 150 pregnant women without pre gestational diabetes including 50 women with low risk factors of diabetes as controls and 50 other pregnant women with pregestational diabetes as control...
2017: PloS One
https://www.readbyqxmd.com/read/28732032/individual-and-area-level-characteristics-associated-with-alcohol-related-mortality-among-adult-lithuanian-males-a-multilevel-analysis-based-on-census-linked-data
#19
Pavel Grigoriev, Domantas Jasilionis, Daumantas Stumbrys, Vladislava Stankūnienė, Vladimir M Shkolnikov
BACKGROUND: Although excessive alcohol-related mortality in the post-Soviet countries remains the major public health threat, determinants of this phenomenon are still poorly understood. AIMS: We assess simultaneously individual- and area-level factors associated with an elevated risk of alcohol-related mortality among Lithuanian males aged 30-64. METHODS: Our analysis is based on a census-linked dataset containing information on individual- and area-level characteristics and death events which occurred between March 1st, 2011 and December 31st, 2013...
2017: PloS One
https://www.readbyqxmd.com/read/28731990/-performance-of-asge-predictive-criteria-in-diagnosis-of-choledocholithiasis-in-the-edgardo-rebagliati-martins-hospital
#20
Harold Eduardo Benites Goñi, Fernando Vicente Palacios Salas, Jairo Luis Asencios Cusihuallpa, Rossmery Aguilar Morocco, Nasthya Solange Segovia Valle
BACKGROUND: In Peru, there are still no local studies designed for evaluating the performance of clinical guidelines designed to stratify patients according to probability of choledocholithiasis. OBJECTIVES: To evaluate the performance of predictive criteria proposed by the American Society for Gastrointestinal Endoscopy (ASGE) in diagnosis of choledocholithiasis. MATERIALS AND METHODS: A retrospective cohort study conducted in a hospital in Lima (Rebagliati hospital)...
April 2017: Revista de Gastroenterología del Perú: órgano Oficial de la Sociedad de Gastroenterología del Perú
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