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https://www.readbyqxmd.com/read/29793212/should-we-excise-are-there-any-clinical-or-histologic-features-that-predict-upgrade-in-papillomas-incidental-or-non-incidental
#1
Michael Zaleski, Yun An Chen, Alison L Chetlen, Julie Mack, Liyan Xu, Daleela G Dodge, Dipti M Karamchandani
The clinical decision to excise intraductal papilloma (IDP) without atypia diagnosed on biopsy remains controversial. We sought to establish clinical and histologic predictors (if any) which may predict upgrade in IDP. 296 biopsies (in 278 women) with histologic diagnosis of IDP without atypia were retrospectively identified and placed into Incidental (no corresponding imaging correlate), or Non-incidental (positive imaging correlate) groups. 253/296 (85.5%) cases were non-incidental, and 43/296 (14.5%) were incidental...
May 11, 2018: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/29793175/apolipoprotein-ciii-and-n-terminal-prohormone-b-type-natriuretic-peptide-as-independent-predictors-for-cardiovascular-disease-in-type-2-diabetes
#2
Marco Colombo, Helen C Looker, Bassam Farran, Felix Agakov, M Julia Brosnan, Paul Welsh, Naveed Sattar, Shona Livingstone, Paul N Durrington, D John Betteridge, Paul M McKeigue, Helen M Colhoun
BACKGROUND AND AIMS: Developing sparse panels of biomarkers for cardiovascular disease in type 2 diabetes would enable risk stratification for clinical decision making and selection into clinical trials. We examined the individual and joint performance of five candidate biomarkers for incident cardiovascular disease (CVD) in type 2 diabetes that an earlier discovery study had yielded. METHODS: Apolipoprotein CIII (apoCIII), N-terminal prohormone B-type natriuretic peptide (NT-proBNP), high sensitivity Troponin T (hsTnT), Interleukin-6, and Interleukin-15 were measured in baseline serum samples from the Collaborative Atorvastatin Diabetes trial (CARDS) of atorvastatin versus placebo...
May 21, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29793128/convolutional-neural-networks-for-seizure-prediction-using-intracranial-and-scalp-electroencephalogram
#3
Nhan Duy Truong, Anh Duy Nguyen, Levin Kuhlmann, Mohammad Reza Bonyadi, Jiawei Yang, Samuel Ippolito, Omid Kavehei
Seizure prediction has attracted growing attention as one of the most challenging predictive data analysis efforts to improve the life of patients with drug-resistant epilepsy and tonic seizures. Many outstanding studies have reported great results in providing sensible indirect (warning systems) or direct (interactive neural stimulation) control over refractory seizures, some of which achieved high performance. However, to achieve high sensitivity and a low false prediction rate, many of these studies relied on handcraft feature extraction and/or tailored feature extraction, which is performed for each patient independently...
May 7, 2018: Neural Networks: the Official Journal of the International Neural Network Society
https://www.readbyqxmd.com/read/29793123/the-beighton-score-as-a-predictor-of-brighton-criteria-in-sport-and-dance
#4
Ross Armstrong, Dr Matt Greig
OBJECTIVES: To determine the efficacy of using the Beighton joint hypermobility score as a predictor of Brighton criteria components, considering the influence of gender and sports participation. DESIGN: Cross sectional study design. SETTING: A University. PARTICIPANTS: Sixty-five female rugby players, 38 male rugby players, 61 netball players, 42 female dancers, 40 male controls and 40 female controls. MAIN OUTCOME MEASURES: The Beighton score was assessed using the Beighton and Horan Joint Mobility Index...
April 20, 2018: Physical Therapy in Sport
https://www.readbyqxmd.com/read/29792992/frailty-status-as-a-predictor-of-three-month-cognitive-and-functional-recovery-following-spinal-surgery-a-prospective-pilot-study
#5
Robert J Rothrock, Jeremy M Steinberger, Henry Badgery, Andrew C Hecht, Samuel K Cho, John M Caridi, Stacie Deiner
Background Context As increasing numbers of elderly Americans undergo spinal surgery, it is important to identify which patients are at highest risk for poor cognitive and functional recovery. Frailty is a geriatric syndrome which has been closely linked to poor outcomes, and short form screening may be a helpful tool for preoperative identification of at risk patients. Purpose To conduct a pilot study on the usefulness of a short-form screening tool to identify elderly patients at increased risk for prolonged cognitive and functional recovery following elective spine surgery...
May 21, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29792938/sella-turcica-bridging-as-a-predictor-of-class-ii-malocclusion-an-investigative-study
#6
Paulami Dasgupta, Sagar Sen, Srikanth Hs, Geetha Kamath
No abstract text is available yet for this article.
May 21, 2018: Journal of Stomatology, Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/29792926/prediction-of-midlife-hand-osteoarthritis-in-young-men
#7
Karin Magnusson, Aleksandra Turkiewicz, Simon Timpka, Martin Englund
OBJECTIVES: Improved prediction modeling in osteoarthritis (OA) may encourage risk reduction through calculation of individual and population lifetime risks. There are currently no prediction models for hand OA. Thus, we aimed to i) develop a prediction model for hand OA in men and ii) to contrast its discriminative performance to a prediction model for lung cancer and chronic obstructive pulmonary disease (COPD). METHODS: We included 40 118 men aged 18 years undergoing mandatory conscription in Sweden 1969-70...
May 21, 2018: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/29792921/characterization-of-solution-stress-degradation-products-of-aliskiren-and-prediction-of-their-physicochemical-and-admet-properties
#8
Bhoopendra Singh Kushwah, Jugal Gupta, Dilip Kumar Singh, Moolchand Kurmi, Archana Sahu, Saranjit Singh
Forced degradation studies on aliskiren were carried out according to ICH and WHO guidelines. Six degradation products were formed in total in the solution state. Their separation among themselves and from the drug was successfully achieved on a C-18 column utilizing acetonitrile and phosphate buffer (pH 3.0) in the mobile phase, which was run in a gradient mode. To characterize them, a complete mass fragmentation pathway of the drug was first established with the help of MS/TOF and MSn data. This was followed by LC-MS/TOF studies on the degradation products...
May 21, 2018: European Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29792564/cognitive-and-behavioral-resilience-among-young-gay-and-bisexual-men-living-with-hiv
#9
Sophia A Hussen, Gary W Harper, Caryn R R Rodgers, Jacob J van den Berg, Nadia Dowshen, Lisa B Hightow-Weidman
PURPOSE: HIV/AIDS disproportionately affects young gay, bisexual, and other men who have sex with men (Y-GBMSM). Resilience remains understudied among Y-GBMSM living with HIV, but represents a potentially important framework for improving HIV-related outcomes in this population. We sought to explore cognitive and behavioral dimensions of resilience and their correlates among Y-GBMSM to gain insights to inform future interventions. METHODS: Our study sample consisted of 200 Y-GBMSM living with HIV enrolled in a multisite study of the Adolescent Medicine Trials Network for HIV/AIDS Interventions (ATN)...
August 2017: LGBT Health
https://www.readbyqxmd.com/read/29792549/analysis-of-the-effects-of-individual-and-community-level-predictors-on-migrant-children-s-primary-immunization-in-yiwu-city-east-china
#10
Yu Hu, Yaping Chen, Liang Hui, Ying Wang
BACKGROUND: To evaluate the effects of a wide range of individual- and community-level factors on migrant children's primary immunization. METHODS: Migrant children aged 13-24 months (born from 1 June 2013 to 31 May 2014) were surveyed in Yiwu city, in June 2015. Social-demographic factors and vaccination records were collected. Five factors at community-level including community wealth, distance to the nearest immunization clinic, maternal education, antenatal clinic (ANC) visits, and hospital delivery were constructed...
May 24, 2018: Human Vaccines & Immunotherapeutics
https://www.readbyqxmd.com/read/29792525/modelling-category-goodness-judgments-in-children-with-residual-sound-errors
#11
Sarah Hamilton Dugan, Noah Silbert, Tara McAllister, Jonathan L Preston, Carolyn Sotto, Suzanne E Boyce
This study investigates category goodness judgments of /r/ in adults and children with and without residual speech errors (RSEs) using natural speech stimuli. Thirty adults, 38 children with RSE (ages 7-16) and 35 age-matched typically developing (TD) children provided category goodness judgments on whole words, recorded from 27 child speakers, with /r/ in various phonetic environments. The salient acoustic property of /r/ - the lowered third formant (F3) - was normalized in two ways. A logistic mixed-effect model quantified the relationships between listeners' responses and the third formant frequency, vowel context and clinical group status...
May 24, 2018: Clinical Linguistics & Phonetics
https://www.readbyqxmd.com/read/29792518/it-is-the-family-context-that-matters-concurrent-and-predictive-effects-of-aspects-of-parent-child-interaction-on-video-gaming-related-problems
#12
Angel Yee-Lam Li, Barbara Chuen-Yee Lo, Cecilia Cheng
Studies have shown that children frequently experiencing poor parent-child interaction are prone to video gaming-related problems, but it is unclear which specific aspects of such an interaction play a predictive role in the problems. To extend previous research that relies primarily on the self-report method to assess parent-child interaction, we conducted a longitudinal, mixed-methods study. In a laboratory setting, three major aspects of interaction (i.e., affectivity, cohesiveness, and parental behavior) were observed in 241 parent-child dyads (Children: 43 percent female, age range = 8-15, Mage  = 12...
May 24, 2018: Cyberpsychology, Behavior and Social Networking
https://www.readbyqxmd.com/read/29792499/teacher-and-student-race-as-a-predictor-for-negative-feedback-during-instruction
#13
Terrance M Scott, Nicholas Gage, Regina Hirn, HyunSuk Han
There is a long and persistent gap between the academic achievement of White and Black students in America's schools. Further, Black students are suspended from school at a rate that is more than three times greater than White students. While there has been some suggestion that perhaps teacher-student racial matching may be part of a solution, the research does not currently provide adequate support for teacher race alone to be sufficiently effective. This study analyzed 41 Black and White teacher-student dyad mixes in elementary schools and another 41 in a high school to examine how teacher and student race interact in terms of teacher and student behaviors...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29792491/does-oral-language-underpin-the-development-of-later-behavior-problems-a-longitudinal-meta-analysis
#14
Jason C Chow, Erik Ekholm, Heather Coleman
OBJECTIVE: The purpose of this article is to estimate the overall weighted mean effect of the relation between early language skills and later behavior problems in school-aged children. METHOD: A systematic literature search yielded 19,790 unduplicated reports, and a structured search strategy and identification procedure yielded 25 unique data sets, with 114 effect sizes for analysis. Eligible reports were then coded, and effect sizes were extracted and synthesized via robust variance estimation and random-effects meta-analytic techniques...
May 24, 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29792368/electrophysiological-multimodal-assessments-improve-outcome-prediction-in-traumatic-cervical-spinal-cord-injury
#15
Markus Hupp, Chiara Pavese, Lucas Bachmann, Rene Koller, Martin Schubert
Outcome prediction after spinal cord injury (SCI) is essential for early counseling and orientation of the rehabilitative intervention. Moreover, prognostication of outcome is crucial to achieve meaningful stratification when conceiving clinical trials. Neurophysiological examinations are commonly employed for prognostication after SCI, but whether neurophysiology could improve the functional prognosis based on clinical predictors remains open. Data of 224 patients included in the European Multicenter Study about Spinal Cord Injury were analyzed with bootstrapping analysis and multivariate logistic regression to derive prediction models of complete functional recovery in chronic stage after traumatic cervical SCI...
May 24, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29792300/what-is-the-effect-of-secondary-high-schooling-on-subsequent-medical-school-performance-a-national-uk-based-cohort-study
#16
Lazaro M Mwandigha, Paul A Tiffin, Lewis W Paton, Adetayo S Kasim, Jan R Böhnke
OBJECTIVES: University academic achievement may be inversely related to the performance of the secondary (high) school an entrant attended. Indeed, some medical schools already offer 'grade discounts' to applicants from less well-performing schools. However, evidence to guide such policies is lacking. In this study, we analyse a national dataset in order to understand the relationship between the two main predictors of medical school admission in the UK (prior educational attainment (PEA) and performance on the United Kingdom Clinical Aptitude Test (UKCAT)) and subsequent undergraduate knowledge and skills-related outcomes analysed separately...
May 23, 2018: BMJ Open
https://www.readbyqxmd.com/read/29792247/spontaneous-version-of-fetal-presentation-in-twin-pregnancies-during-third-trimester-longitudinal-assessment
#17
Jeong Woo Park, Seung Mi Lee, Hye-Sim Kang, Soon-Sup Shim, Jong Kwan Jun
Little is known about longitudinal changes of the first twin presentation in twin gestations. This is a retrospective cohort study including 411 women who were admitted consecutively and delivered live-born twins at 36 weeks of gestation or more. Longitudinal assessment of the first twin presentation was conducted during gestation and at birth in all cases. Gestational age at antenatal assessment was divided into two intervals: early-third trimester (28-31 weeks) and mid-third trimester (32-35 weeks). Fetal presentation was categorized as vertex or non-vertex...
June 2018: Twin Research and Human Genetics: the Official Journal of the International Society for Twin Studies
https://www.readbyqxmd.com/read/29792244/affective-problems-and-decline-in-cognitive-state-in-older-adults-a-systematic-review-and-meta-analysis
#18
A John, U Patel, J Rusted, M Richards, D Gaysina
Evidence suggests that affective problems, such as depression and anxiety, increase risk for late-life dementia. However, the extent to which affective problems influence cognitive decline, even many years prior to clinical diagnosis of dementia, is not clear. The present study systematically reviews and synthesises the evidence for the association between affective problems and decline in cognitive state (i.e., decline in non-specific cognitive function) in older adults. An electronic search of PubMed, PsycInfo, Cochrane, and ScienceDirect was conducted to identify studies of the association between depression and anxiety separately and decline in cognitive state...
May 24, 2018: Psychological Medicine
https://www.readbyqxmd.com/read/29792236/evaluation-of-gamma-radiation-induced-biochemical-changes-in-skin-for-dose-assesment-a-study-on-small-experimental-animals
#19
Sandeep Kumar Soni, Mitra Basu, Priyanka Agrawal, Aseem Bhatnagar, Neelam Chhillar
OBJECTIVE: Researchers have been evaluating several approaches to assess acute radiation injury/toxicity markers owing to radiation exposure. Keeping in mind this background, we assumed that whole-body irradiation in single fraction in graded doses can affect the antioxidant profile in skin that could be used as an acute radiation injury/toxicity marker. METHODS: Sprague-Dawley rats were treated with CO-60 gamma radiation (dose: 1-5 Gy; dose rate: 0.85 Gy/minute)...
May 24, 2018: Disaster Medicine and Public Health Preparedness
https://www.readbyqxmd.com/read/29792231/high-burden-of-birthweight-lowering-genetic-variants-in-africans-and-asians
#20
Fasil Tekola-Ayele, Tsegaselassie Workalemahu, Azmeraw T Amare
BACKGROUND: Birthweight is an important predictor of infant morbidity and mortality, and is associated with cardiovascular diseases, obesity, and diabetes in childhood and adulthood. Birthweight and fetal growth show regional and population variations even under similar maternal conditions, and a large proportion of these differences are not explained by environmental factors. Whether and to what extent population genetic variations at key birthweight-associated loci account for the residual birthweight disparities not explained by environmental determinants is unknown...
May 24, 2018: BMC Medicine
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