Caecilia S E Doorenbos, Jip Jonker, Jiasi Hao, Edmund J Gore, Daan Kremer, Tim J Knobbe, Anoek A E de Joode, Jan Stephan F Sanders, Olivier Thaunat, Hubert G M Niesters, Coretta C Van Leer-Buter, Stephan J L Bakker
Torque Teno Virus (TTV) is a non-pathogenic virus that is highly prevalent among kidney transplant recipients (KTRs). Its circulating load is associated with an immunological status in KTR and is considered a promising tool for guiding immunosuppression. To allow for optimal guidance, it is important to identify other determinants of TTV load. We aimed to investigate the potential association of smoking and alcohol intake with TTV load. For this cross-sectional study, serum TTV load was measured using PCR in stable kidney transplant recipients at ≥1 year after transplantation, and smoking status and alcohol intake were assessed through questionnaires and measurements of urinary cotinine and ethyl glucuronide...
December 6, 2023: Viruses