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https://www.readbyqxmd.com/read/27898350/cronkhite-canada-syndrome-complicated-by-pulmonary-embolism-a-case-report
#1
Neha L Nemade, Urvi B Shukla, Gajanan D Wagholikar
INTRODUCTION: Cronkhite Canada Syndrome (CCS) is a rare syndrome, described in 1955 by Americans, Leonard Wolsey Cronkhite and Wilma Jeanne Canada in the New England Journal of Medicine [1]. About 450 cases have been reported. Complications, like malignant transformation, unprovoked thromboembolism is known. Since there is wide variability in medical presentation, no definitive diagnostic and treatment protocol s have been set. The mortality remains at 55%. CASE PRESENTATION: We report a case of a 50 year old male patient presenting with diarrhea, weight loss, abdominal pain, ectodermal features...
November 17, 2016: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/27854093/posterior-reversible-encephalopathy-syndrome-mimicking-brainstem-infarction-a-dilemma
#2
Tsung-Han Ho, Chia-Lin Tsai, Yaw-Don Hsu, Jiunn-Tay Lee, Fu-Chi Yang, Chia-Ching Hsu, Chun-Chieh Lin
PURPOSE: We had recently reported one case at American Journal of Emergency Medicine about centralvariant posterior reversible encephalopathy syndrome (PRES) in an 84-year-old woman with an initial misdiagnosis as central pontine myelinolysis (CPM). Here, we introduce another case of centralvariant PRES in a 49-year-old man mimicking as acute brainstem infarction in the cranial computed tomography (CT) findings. CASE REPORT: A 49-year-old man was admitted to the emergency department with a 5-day history of vertigo, cognitive decline, and difficulty in walking...
June 15, 2016: Acta Neurologica Taiwanica
https://www.readbyqxmd.com/read/27831548/a-novel-more-efficient-staged-approach-for-critical-congenital-heart-disease-screening
#3
J Mouledoux, S Guerra, J Ballweg, Y Li, W Walsh
OBJECTIVE: Screening for critical congenital heart disease (CCHD) using pulse oximetry has been endorsed by the American Academy of Pediatrics and the American Heart Association. The recommended screening requires two saturation readings. We sought to determine the incidence of undetected CCHD in Tennessee for the 2 years following implementation of an algorithm that assigned an immediate pass to a single lower extremity saturation of 97% or higher. STUDY DESIGN: State Genetic Screening records and reports of missed cases from the Tennessee Initiative for Perinatal Quality Care were used to determine if CCHD cases were missed by the new screening algorithm...
November 10, 2016: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27436264/copy-number-variations-in-375-patients-with-oesophageal-atresia-and-or-tracheoesophageal-fistula
#4
Erwin Brosens, Florian Marsch, Elisabeth M de Jong, Hitisha P Zaveri, Alina C Hilger, Vera Gisela Choinitzki, Alice Hölscher, Per Hoffmann, Stefan Herms, Thomas M Boemers, Benno M Ure, Martin Lacher, Michael Ludwig, Bert H Eussen, Robert M van der Helm, Hannie Douben, Diane Van Opstal, Rene M H Wijnen, H Berna Beverloo, Yolande van Bever, Alice S Brooks, Hanneke IJsselstijn, Daryl A Scott, Johannes Schumacher, Dick Tibboel, Heiko Reutter, Annelies de Klein
Oesophageal atresia (OA) with or without tracheoesophageal fistula (TOF) are rare anatomical congenital malformations whose cause is unknown in over 90% of patients. A genetic background is suggested, and among the reported genetic defects are copy number variations (CNVs). We hypothesized that CNVs contribute to OA/TOF development. Quantifying their prevalence could aid in genetic diagnosis and clinical care strategies. Therefore, we profiled 375 patients in a combined Dutch, American and German cohort via genomic microarray and compared the CNV profiles with their unaffected parents and published control cohorts...
July 20, 2016: European Journal of Human Genetics: EJHG
https://www.readbyqxmd.com/read/27433299/levels-of-evidence-in-the-treatment-of-slipped-capital-femoral-epiphysis-a-systematic-review
#5
Andrew Moriarity, Jim Kennedy, Joe Baker, Pat Kiely
The primary aim of this study was to analyze the current level of evidence available on the surgical management of Slipped Capital Femoral Epiphysis (SCFE). Secondary aims were to correlate the level of evidence with the impact factor of the journal to evaluate the level of evidence over time, and to evaluate the geographic distribution of the studies. Therapeutic studies published in English between January 1991 and August 2014 that reported on SCFE were identified via electronic search was performed using the databases PubMed, EMBASE, and the Cochrane Library...
June 27, 2016: Orthopedic Reviews
https://www.readbyqxmd.com/read/27405471/breast-cancer-policy-in-latin-america-account-of-achievements-and-challenges-in-five-countries
#6
Gustavo Nigenda, Maria Cecilia Gonzalez-Robledo, Luz Maria Gonzalez-Robledo, Rosa Maria Bejarano-Arias
BACKGROUND: The recent increase of breast cancer mortality has put on alert to most countries in the region. However it has taken some time before breast cancer could be considered as a relevant problem. Only in recent years breast cancer has been considered a priority in some Latin American countries and resources have been mobilized to confront the problem at the institutional level. The article analyzes the efforts made in five Latin American countries (Argentina, Brazil, Colombia, Mexico and Venezuela) in the last 15 years to design and implement policies to address the growing incidence of breast cancer...
2016: Globalization and Health
https://www.readbyqxmd.com/read/27197976/income-inequality-and-child-mortality-in-wealthy-nations
#7
David Collison
This chapter presents evidence of a relationship between child mortality data and socio-economic factors in relatively wealthy nations. The original study on child mortality that is reported here, which first appeared in a UK medical journal, was undertaken in a school of business by academics with accounting and finance backgrounds. The rationale explaining why academics from such disciplines were drawn to investigate these issues is given in the first part of the chapter. The findings related to child mortality data were identified as a special case of a wide range of social and health indicators that are systematically related to the different organisational approaches of capitalist societies...
2016: World Review of Nutrition and Dietetics
https://www.readbyqxmd.com/read/27171652/psychosocial-interventions-for-improving-quality-of-life-outcomes-in-adults-undergoing-strabismus-surgery
#8
REVIEW
Kelly MacKenzie, Joanne Hancox, Hayley McBain, Daniel G Ezra, Gill Adams, Stanton Newman
BACKGROUND: Strabismus, also known as squint, can have a debilitating effect on a person's self-esteem, quality of life and mood, as well as increase their feelings of social anxiety and avoidance behaviour. Strabismus surgery can improve both the alignment of a person's eyes and, in appropriate cases, relieve symptoms such as double vision. However, evidence indicates that not all patients experience a meaningful improvement in their quality of life postsurgery. Pre-surgical psychosocial interventions have been found to improve patient reported outcomes in other long-term conditions...
2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27149124/future-of-dermatovenereological-journals1
#9
EDITORIAL
Branka Marinović
Each year, during the Annual Meeting of the American Academy of Dermatology, there is a meeting of the Council of Dermatology Editors organized by Professor Larry Parish from Philadelphia. It is so nice to meet old friends there and make some new ones, but above all it is a very good platform to discuss the problems journals and their editors are facing today. Some of the topics we discussed during this year's meeting were the increasing number of case reports submitted to all dermatological journals, problems of plagiarism, the rising number of online journals, and the predatory policies quite often connected with them...
April 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/27101814/a-bibliometric-analysis-of-statistical-terms-used-in-american-physical-therapy-association-journals-2011-2012-evidence-for-educating-physical-therapists
#10
Julie K Tilson, Katie Marshall, Jodi J Tam, Linda Fetters
BACKGROUND: A primary barrier to the implementation of evidence based practice (EBP) in physical therapy is therapists' limited ability to understand and interpret statistics. Physical therapists demonstrate limited skills and report low self-efficacy for interpreting results of statistical procedures. While standards for physical therapist education include statistics, little empirical evidence is available to inform what should constitute such curricula. The purpose of this study was to conduct a census of the statistical terms and study designs used in physical therapy literature and to use the results to make recommendations for curricular development in physical therapist education...
2016: BMC Medical Education
https://www.readbyqxmd.com/read/27087121/insulin-and-oral-agents-for-managing-cystic-fibrosis-related-diabetes
#11
REVIEW
Gary M Onady, Adrienne Stolfi
BACKGROUND: The Cystic Fibrosis Foundation recommends both short-term and long-acting insulin therapy when cystic fibrosis-related diabetes has been diagnosed. Diagnosis is based on: an elevated fasting blood glucose level greater than 6.94 mmol/liter (125 mg/deciliter); or oral glucose tolerance tests greater than 11.11 mmol/liter (200 mg/deciliter) at two hours; or symptomatic diabetes for random glucose levels greater than 11.11 mmol/liter (200 mg/deciliter); or glycated hemoglobin levels of at least 6...
April 18, 2016: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/27028494/are-private-interests-clouding-the-peer-review-process-of-the-who-bulletin-a-case-study
#12
Nuria Homedes, Antonio Ugalde
Readers' trust on the medical literature has been eroded, and journal editors and some editorial boards are taking measures to ensure that authors fully and accurately report research findings and disclose conflicts of interest. This article describes a case study in which the papers editor of the World Health Organization (WHO) Bulletin influenced the content of an article that had been approved by the external reviewers. The editor objected to the publication of the large price differentials of the new molecular entities (NMEs) across the Latin American countries where they had been tested and the limited added therapeutic value of the NMEs that had been assessed by independent drug bulletins...
2016: Accountability in Research
https://www.readbyqxmd.com/read/27020716/conflict-of-interests-for-radiation-oncologists-harnessing-disclosures-from-policy-to-reality
#13
J-B Guy, A Vallard, S Espenel, J Langrand-Escure, J-C Trone, B Méry, M Ben Mrad, P Diao, C Mattevi, C Chargari, N Magné
PURPOSE: An increasing attention is being paid to disclosures of conflicts of interests in the field of oncology. The purpose of this study was to examine how radiation oncologists report their conflicts of interests with pharmaceutical or technology industries. MATERIALS AND METHODS: We collected the data of conflicts of interests disclosures in the abstract books from the annual 2012 and 2013 meetings of the American Society for Radiation Oncology (ASTRO) in Miami (FL, USA), and in Atlanta (GA, USA), respectively...
May 2016: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
https://www.readbyqxmd.com/read/26968334/15q13-3-duplication-in-two-patients-with-childhood-onset-schizophrenia
#14
Dale Zhou, Peter Gochman, Diane D Broadnax, Judith L Rapoport, Kwangmi Ahn
We report two cases of paternally inherited 15q13.3 duplications in carriers diagnosed with childhood-onset schizophrenia (COS), a rare neurodevelopmental disorder of proposed polygenic origin with onset in children before age 13. This study documents that the 15q13.3 deletion and duplication exhibit pathogenicity for COS, with both copy number variants (CNVs) sharing a disrupted CHRNA7 gene. CHRNA7 encodes the neuronal alpha7 nicotinic acetylcholine receptor (α7nAChR) and is a candidate gene that has been suggested as a pathophysiological process mediating adult-onset schizophrenia (AOS) and other neurodevelopmental disorders...
September 2016: American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics
https://www.readbyqxmd.com/read/26908324/analgesic-medication-use-and-risk-of-epithelial-ovarian-cancer-in-african-american-women
#15
COMPARATIVE STUDY
Lauren C Peres, Fabian Camacho, Sarah E Abbott, Anthony J Alberg, Elisa V Bandera, Jill Barnholtz-Sloan, Melissa Bondy, Michele L Cote, Sydnee Crankshaw, Ellen Funkhouser, Patricia G Moorman, Edward S Peters, Ann G Schwartz, Paul Terry, Frances Wang, Joellen M Schildkraut
BACKGROUND: Existing literature examining analgesic medication use and epithelial ovarian cancer (EOC) risk has been inconsistent, with the majority of studies reporting an inverse association. Race-specific effects of this relationship have not been adequately addressed. METHODS: Utilising data from the largest population-based case-control study of EOC in African Americans, the African American Cancer Epidemiology Study, the relationship between analgesic use (aspirin, non-aspirin nonsteroidal anti-inflammatory drugs (NSAIDs), and acetaminophen) and risk of EOC was estimated by multivariate logistic regression...
March 29, 2016: British Journal of Cancer
https://www.readbyqxmd.com/read/26859110/-psychotraumatological-defence-mechanisms-in-the-print-media-coverage-of-september-11
#16
Jessica Helen Huss, Christiane Eichenberg
INTRODUCTION: Media have a significant influence on the perception of mental disorders in society. Especially in the case of traumatizations, the indirect confrontation with a traumatic event will lead to the application of psychotraumatological defence mechanisms aiming at retaining an illusory sense of security. Experts assume that journalists are also making use of psychotraumatological defence when reporting on disasters in print media. This, in turn, will influence the reception of traumatic events in the public in general and in the construction of victim and perpetrator in particular...
February 2016: Psychotherapie, Psychosomatik, Medizinische Psychologie
https://www.readbyqxmd.com/read/26808309/agreements-and-discrepancies-between-fda-reports-and-journal-papers-on-biologic-agents-approved-for-rheumatoid-arthritis-a-meta-research-project
#17
Gil Amarilyo, Daniel E Furst, Jennifer M P Woo, Wen Li, Henning Bliddal, Robin Christensen, Simon Tarp
BACKGROUND: Sponsors that seek to commercialize new drugs apply to the Food and Drug Administration (FDA) which independently analyzes the raw data and reports the results on its website. OBJECTIVES: This study sought to determine if there are differences between the FDA assessments and journal reports on biologic agents developed for the treatment of rheumatoid arthritis. METHODS: Available data on FDA-approved drugs were extracted from the website, and a systematic literature search was conducted to identify matching studies in peer-reviewed medical journals...
2016: PloS One
https://www.readbyqxmd.com/read/26786879/associations-between-resident-physicians-publications-and-clinical-performance-during-residency-training
#18
Luke A Seaburg, Amy T Wang, Colin P West, Darcy A Reed, Andrew J Halvorsen, Gregory Engstler, Amy S Oxentenko, Thomas J Beckman
BACKGROUND: Both research and clinical medicine requires similar attributes of efficiency, diligence and effective teamwork. Furthermore, residents must succeed at scholarship and patient care to be competitive for fellowship training. It is unknown whether research productivity among residents is related to broad measures of clinical achievement. Our goal was to examine associations between the quantity of internal medicine residents' publications and validated measures of their knowledge, skills and multi-source evaluations of performance...
2016: BMC Medical Education
https://www.readbyqxmd.com/read/26568574/snippets-from-the-past-imaginative-designs-separating-hereditary-from-environmental-effects-in-pre-dna-times
#19
Alfredo Morabia
In an attempt to reproduce the results of an inconclusive 1927 report by the British Medical Research Council on the hereditary versus social origins of rheumatic fever, Read, Ciocco, and Taussig, from Johns Hopkins University, with the support of Frost, conducted a case-control study in 1935 and 1936. Their study, which appeared in the American Journal of Hygiene in 1938, was outstanding for its clear and tidy rationale for separating hereditary from environmental causes. The authors compared the prevalence of rheumatic fever among the relatives of 33 children admitted for "incident" rheumatic fever and 33 control children admitted in a tuberculosis clinic for reasons other than rheumatic fever...
December 1, 2015: American Journal of Epidemiology
https://www.readbyqxmd.com/read/26545643/-methodology-review-for-writing-and-publishing-case-report-applications-on-the-nutrition-field
#20
Gerardo Martínez Martínez, Ana Lucia Noreña, José Miguel Martínez Sanz, Rocío Ortiz Moncada
INTRODUCTION: currently, case reports are an important teaching tool with practical applications and contribute to the expansion of knowledge of health professionals. OBJECTIVE: to review the methodology of developing case reports, showing similarities and differences in format and content criteria that are requested for case reports to be published. METHODOLOGY: literature review in PubMed and Scielo between 2005-2015 and manual tracing of the most relevant references of selected articles...
2015: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
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