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https://www.readbyqxmd.com/read/28648141/anesthetic-management-of-spontaneous-cervical-epidural-hematoma-during-pregnancy-a-case-report
#1
Mehdi Samali, Abdelghafour Elkoundi, Achraf Tahri, Mustapha Bensghir, Charki Haimeur
BACKGROUND: Spontaneous spinal epidural hematoma during pregnancy is a quite rare event requiring emergent decompressive surgery in the majority of cases to prevent permanent neurological damage. Therefore, there is little data in the literature regarding anesthetic management of cervical localization during pregnancy. The potential for difficult airway management with the patient under general anesthesia is one of the major concerns that needs to be addressed to prevent further cord compression...
June 26, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/28648115/complete-thoracolumbar-fracture-dislocation-with-intact-neurologic-function-explanation-of-a-novel-cord-saving-mechanism
#2
Abolfazl Rahimizadeh, Naser Asgari, Ava Rahimizadeh
BACKGROUND: The thoracolumbar junction from T11 to L2 is a common site of injury in which fracture and dislocations are the most prevalent ones occurring at this location. Fracture dislocation is defined as failure of all three columns of the spine with gross displacement. Considering the significant violence necessary to produce fracture dislocations, these injuries are often associated with major neural deficit, with the majority of casualties becoming paraplegic immediately. Preservation of neurological function following complete fracture dislocation is quite rare entity...
June 26, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28642653/clinical-application-of-a-drill-guide-template-for-pedicle-screw-placement-in-severe-scoliosis
#3
Xin Li, Yaoshen Zhang, Qiang Zhang, Changsong Zhao, Kun Liu
OBJECTIVE: To evaluate the accuracy and the effect of drill guide template for pedicle screw placement in severe scoliosis. METHOD: Eight patients with rigid scoliosis were enrolled, five males and three females, ranging from nine to 23 years old. A three-dimensional CT scan of the spine was performed and saved as a DICOM file type. The multi-level template was designed by Mimics software and manufactured according to the part of the most severe deformity. The drill template was placed on the corresponding vertebral surface...
March 2017: Acta Ortopedica Brasileira
https://www.readbyqxmd.com/read/28638473/rapid-fluorescence-imaging-of-spinal-cord-following-epidural-administration-of-a-nerve-highlighting-fluorophore
#4
Wanguo Liu, Rui Gu, Qingsan Zhu, Chunsheng Xiao, Lanfeng Huang, Xinming Zhuang, Jingzhe Zhang, Lidi Liu, Ben Ma, Huailin Yang, Jianchao Ma, Zhipeng Hu, Chenglin Tang, Shuhua Zhao, Xuesi Chen
Iatrogenic spinal cord injury (SCI) is the most devastating complication of spine surgery, which usually results in permanent and serious disabilities of patients. Improvement of the visualization and discrimination of the spinal cord is critical for accuracy and safety during surgery; however, to date, there is no suitable technology to fulfill this clinical need. Here, we first show an efficient and rapid fluorescence imaging of the spinal cord in rabbit by epidural administration of a nerve-highlighting fluorophore, i...
2017: Theranostics
https://www.readbyqxmd.com/read/28620739/injuries-of-the-spine-and-of-the-spinal-cord-in-the-hippocratic-corpus-of-medicine
#5
REVIEW
Demetrios Korres, Konstantinos Markatos, Demetrios Chytas, Anastasios Andreakos, Andreas Mavrogenis
The purpose of this review article is to summarize the views presented in the Hippocratic Corpus of Medicine regarding injuries of the spine, their effect on the spinal cord and the optimal treatment modulus. It is shown that the treatment dilemmas of ancient times in these injuries remain modern since Hippocrates suggested that conservative treatment and letting nature take its course is preferable over a devastating surgical treatment if the spinal cord structural integrity is not compromised. There is also a detailed account of the conservative treatment suggested in the Hippocratic Corpus concerning devices and method of closed spinal relocations...
June 16, 2017: International Orthopaedics
https://www.readbyqxmd.com/read/28616030/time-lapse-changes-of-in-vivo-injured-neuronal-substructures-in-the-central-nervous-system-after-low-energy-two-photon-nanosurgery
#6
Zhikai Zhao, Shuangxi Chen, Yunhao Luo, Jing Li, Smaranda Badea, Chaoran Ren, Wutian Wu
There is currently very little research regarding the dynamics of the subcellular degenerative events that occur in the central nervous system in response to injury. To date, multi-photon excitation has been primarily used for imaging applications; however, it has been recently used to selectively disrupt neural structures in living animals. However, understanding the complicated processes and the essential underlying molecular pathways involved in these dynamic events is necessary for studying the underlying process that promotes neuronal regeneration...
May 2017: Neural Regeneration Research
https://www.readbyqxmd.com/read/28607823/traumatic-spondyloptosis-of-the-cervical-spine-a-case-report-and-discussion-of-worldwide-treatment-trends
#7
Kelly E Wong, Peter S Chang, Mark S Monasky, Rodney M Samuelson
BACKGROUND: Cervical spondyloptosis is defined as the dislocation of the spinal column most often caused by trauma. Due to compression or transection of the spinal cord, severe neurological deficits are common. Here, we review the literature and report a case of traumatic C5-6 spondyloptosis that was successfully treated using an anterior-only surgical approach. METHODS: The patient presented with quadriplegia and absent sensation distal to the C5 dermatome following a rollover motor vehicle accident...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28607524/development-of-a-modified-model-of-spinal-cord-ischemia-injury-by-selective-ligation-of-lumbar-arteries-in-rabbits
#8
W Xiao, J Wen, Y-C Huang, B-S Yu
STUDY DESIGN: Experimental study. OBJECTIVE: The aim of this study is to develop a modified model of spinal cord ischemia in rabbits. SETTINGS: Shenzhen Key Laboratory of Spine Surgery, Shenzhen, China. METHODS: In total, 20 New Zealand rabbits were divided into the following four groups according to the level of ligation of bilateral lumbar arteries: (1) group A, sham group, no ligation, n=5; (2) group B, ligation of bilateral lumbar arteries at three levels (L2-L4, n=5); (3) group C, ligation of bilateral lumbar arteries at four levels (L2-L5, n=5); and (4) group D, ligation of bilateral lumbar arteries at five levels (L1-L5, n=5)...
June 13, 2017: Spinal Cord
https://www.readbyqxmd.com/read/28604497/potential-mechanism-for-some-post-operative-c5-palsies-an-anatomical-study
#9
Fernando Alonso, Vlad Voin, Joe Iwanaga, David Hanscom, Jens R Chapman, Rod J Oskouian, Marios Loukas, R Shane Tubbs
STUDY DESIGN: Anatomical Study. OBJECTIVE: Determine if shoulder depression (e.g., taping the shoulders) might result in C5 nerve traction and subsequent injury. SUMMARY OF BACKGROUND DATA: Postoperative C5 nerve palsy is a recognized entity that is still often enigmatic. Inferior shoulder depression is usually employed to assist with surgical visualization during cervical spine procedures. METHODS: In the supine position, ten adult fresh frozen human cadavers underwent dissection of the spinal cord and its adjacent dorsal, ventral roots and spinal nerves from C4 to T1...
June 9, 2017: Spine
https://www.readbyqxmd.com/read/28594515/cervical-spine-injuries-in-the-athlete
#10
Gregory D Schroeder, Alexander R Vaccaro
Cervical spine injuries are common and range from relatively minor injuries, such as cervical muscle strains, to severe, life-threatening cervical fractures with spinal cord injuries. Although cervical spine injuries are most common in athletes who participate in contact and collision sports, such as rugby and American football, they also have been reported in athletes who participate in noncontact sports, such as baseball, gymnastics, and diving. Cervical spine injuries in athletes are not necessarily the result of substantial spine trauma; some athletes have chronic conditions, such as congenital stenosis, that increase their risk for a serious cervical spine injury after even minor trauma...
February 15, 2017: Instructional Course Lectures
https://www.readbyqxmd.com/read/28578163/efficacy-and-safety-of-urinary-catheters-with-silver-alloy-coating-in-spinal-cord-injured-patients-a-multicentric-pragmatic-randomized-controlled-trial-the-escale-trial
#11
Xavier Bonfill, David Rigau, Manuel E Fuertes, Juana M Barrera-Chacón, María L Jáuregui-Abrisqueta, Sebastian Salvador, Carolina M Alemán-Sánchez, Albert Borau, Manuel Bea-Muñoz, Begoña Hidalgo, Maria J Andrade, Juan R Espinosa, María José Martínez-Zapata
BACKGROUND: Patients with spinal cord injury (SCI) that carry indwelling urinary catheters have an increased risk of urinary tract infection (UTIs). Antiseptic Silver Alloy-Coated silicone (SAC) urinary catheters prove to be a promising intervention to reduce UTIs; however, current evidence cannot be extrapolated to spinal cord injured patients. PURPOSE: Assess the efficacy of SAC urinary catheters for preventing catheter-associated urinary tract infections (CA-UTI)...
May 31, 2017: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/28578140/effectiveness-of-an-innovative-hip-energy-storage-walking-orthosis-for-improving-paraplegic-walking-a-pilot-randomized-controlled-study
#12
Mingliang Yang, Jianjun Li, Xinyu Guan, Lianjun Gao, Feng Gao, Liangjie Du, Hongmei Zhao, Degang Yang, Yan Yu, Qimin Wang, Rencheng Wang, Linhong Ji
BACKGROUND: The high energy cost of paraplegic walking using a reciprocating gait orthosis (RGO) is attributed to limited hip motion and excessive upper limb loading for support. To address the limitation, we designed the hip energy storage walking orthosis (HESWO) which uses a spring assembly on the pelvic shell to store energy from the movements of the healthy upper limbs and flexion-extension of the lumbar spine and hip and returns this energy to lift the pelvis and lower limb to assist with the swing and stance components of a stride...
May 24, 2017: Gait & Posture
https://www.readbyqxmd.com/read/28572150/percutaneous-spinal-ablation-in-a-sheep-model-protective-capacity-of-an-intact-cortex-correlation-of-ablation-parameters-with-ablation-zone-size-and-correlation-of-postablation-mri-and-pathologic-findings
#13
A N Wallace, T J Hillen, M V Friedman, Z S Zohny, B H Stephens, S C Greco, M R Talcott, J W Jennings
BACKGROUND AND PURPOSE: Despite the growing use of percutaneous ablation therapy for the treatment of metastatic spine disease, several issues have yet to be fully addressed. Our aims were to determine whether the vertebral body cortex protects against ablation-induced spinal cord injury; correlate radiofrequency, cryo-, and microwave ablation parameters with resulting spinal ablation zone dimensions and describe normal spinal marrow postablation changes on MR imaging. MATERIALS AND METHODS: Ten thoracolumbar vertebrae in 3 sheep were treated with radiofrequency ablation, cryoablation, or microwave ablation under fluoroscopic guidance...
June 1, 2017: AJNR. American Journal of Neuroradiology
https://www.readbyqxmd.com/read/28571527/assessment-and-management-of-acute-spinal-cord-injury-from-point-of-injury-to-rehabilitation
#14
Laureen D Hachem, Christopher S Ahuja, Michael G Fehlings
CONTEXT: Spinal cord injury (SCI) is a devastating condition that can lead to significant neurological impairment and reduced quality of life. Despite advancements in our understanding of the pathophysiology and secondary injury mechanisms involved in SCI, there are currently very few effective treatments for this condition. The field, however, is rapidly changing as new treatments are developed and key discoveries are made. METHODS: In this review, we outline the pathophysiology, management, and long-term rehabilitation of individuals with traumatic SCI...
June 1, 2017: Journal of Spinal Cord Medicine
https://www.readbyqxmd.com/read/28565999/ryk-receptors-on-unmyelinated-nerve-fibers-mediate-excitatory-synaptic-transmission-and-ccl2-release-during-neuropathic-pain-induced-by-peripheral-nerve-injury
#15
Qing Ou Yang, Wen-Jing Yang, Jian Li, Fang-Ting Liu, Hongbin Yuan, Yue-Ping Ou Yang
Background Neuropathic pain is a major pathology of the central nervous system associated with neuroinflammation. Ryk (receptor-like tyrosine kinase) receptors act as repulsive axon-guidance molecules during development of central nervous system and neural injury. Increasing evidence suggests the potential involvement of Wnt/Ryk (wingless and Int) signaling in the pathogenesis of neuropathic pain. However, its underlying mechanism remains unknown. Results The expression and location of Ryk receptor as well as its ligand Wnt1 were detected by qPCR, Western blot, and immunohistochemistry...
January 2017: Molecular Pain
https://www.readbyqxmd.com/read/28562167/previously-identified-common-post-injury-adverse-events-in-traumatic-spinal-cord-injury-validation-of-existing-literature-and-relation-to-selected-potentially-modifiable-comorbidities-a-prospective-canadian-cohort-study
#16
Travis E Marion, Carly S Rivers, Dilnur Kurban, Christiana L Cheng, Nader Fallah, Juliet Batke, Marcel F Dvorak, Charles G Fisher, Brian K Kwon, Vanessa K Noonan, John Street
Adverse events (AEs) are common during care in patients with traumatic spinal cord injury (tSCI). Increased risk of AEs is linked to patient factors including pre--existing comorbidities. Our aim was to examine the relationships between patient factors and common post--injury AEs, and identify potentially modifiable comorbidities. Adults with tSCI admitted at a Level I acute specialized spine centre between 2006--2014 who were included in the Rick Hansen SCI Registry (RHSCIR) and had AE data collected using the Spine Adverse Events Severity (SAVES) system were included...
May 31, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28540126/neurological-complications-of-lumbar-and-cervical-dural-punctures-with-a-focus-on-epidural-injections
#17
Nancy E Epstein
BACKGROUND: Various types of lumbar dural punctures may contribute to neurological injury. The etiologies of dural injury include; inadvertent dural punctures due to epidurals placed for labor anesthesia, epidural steroid injections (ESI/transforaminal TESI; approximately 9 million ESI performed in the US per year), deliberate placement of intradural pain devices, and spontaneous cerebrospinal fluid (CSF) fistulas. Resulting neurological complications may include; spinal headaches/intracranial hypotension, subdural hematomas, and 6(th) nerve cranial palsies...
2017: Surgical Neurology International
https://www.readbyqxmd.com/read/28540118/spinal-cord-injury-in-the-geriatric-population-risk-factors-treatment-options-and-long-term-management
#18
REVIEW
Tochukwu C Ikpeze, Addisu Mesfin
Spinal cord injuries (SCIs) are sustained by more than 12 500 patients per year in the United States and more globally. The SCIs disproportionately affect the elderly, especially men. Approximately 60% of these injuries are sustained traumatically through falls, but nontraumatic causes including infections, tumors, and medication-related epidural bleeding have also been documented. Preexisting conditions such as ankylosing spondylitis and diffuse idiopathic skeletal hyperostosis can render the spine stiff and are risk factors as well as cervical spondylosis and ensuing cervical stenosis...
June 2017: Geriatric Orthopaedic Surgery & Rehabilitation
https://www.readbyqxmd.com/read/28538594/trends-in-patient-care-for-traumatic-spinal-injuries-in-the-united-states-a-national-inpatient-sample-study-of-the-correlations-with-patient-outcomes-from-2001-to-2012
#19
Christopher M Holland, Marcus D Mazur, Erica F Bisson, Meic H Schmidt, Andrew T Dailey
STUDY DESIGN: Retrospective database review OBJECTIVE.: To examine whether patient characteristics, distribution of care, and patient outcomes for spinal cord injury (SCI) in the United States have changed between 2001 and 2012. SUMMARY OF BACKGROUND DATA: Although patient outcomes after cranial injury are better at high-volume centers with specialized, multidisciplinary teams, similar assessments have not been done for spinal injuries. METHODS: We retrospectively reviewed the National and Nationwide Inpatient Samples for the years 2001, 2002, 2011, and 2012 to identify patients with spinal fracture with or without SCI...
May 22, 2017: Spine
https://www.readbyqxmd.com/read/28536800/causes-and-preventive-measures-of-symptomatic-spinal-epidural-haematoma-after-spinal-surgery
#20
Xiao-Jun Zeng, Wei Wang, Zhou Zhao, Ming Li
STUDY DESIGN: This was a retrospective study to evaluate clinical characteristics of patients who developed symptomatic spinal epidural haematoma (SSEH) after spinal surgery. OBJECTIVE: The objective was to determine clinical parameters associated with the development of SSEH after spinal surgery, and to discuss clinical management and possible preventive measures. Although the incidence rate of SSEH is low, the neurological sequelae are devastating. There are limited reports which identify risk factors for SSEH because of the rarity of the condition...
May 24, 2017: International Orthopaedics
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