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memory implant

Xing Zhou Qu, Ming Yi Wang, Hui Shan Ong, Chen Ping Zhang
OBJECTIVES: This study aimed to evaluate the stability of prostheses supported by zygoma implants and remaining teeth for subjects who had undergone hemi-maxillectomy. METHODS: Ten patients were included in the study. Oral rehabilitation was performed using a temporary prosthesis that was supported by remaining teeth for the first three months. Then, a zygoma implant was placed to provide support for a final prosthesis in addition to the remaining teeth. Each prosthesis was tailor-made according to biomechanical three-dimensional finite element analysis results...
October 1, 2016: Clinics
David S Xu, Francisco Ponce
High-frequency deep brain stimulation (DBS) is a neurosurgical procedure that was introduced in the late 1980s for the treatment of movement disorders. It is a reversible, adjustable, and non-ablative therapy that has been used in over 100,000 people worldwide. The surgical procedure used to implant the DBS system, as well as the effects of chronic electrical stimulation, have been shown to be safe and effective through many clinical trials. The ability to therapeutically modulate the motor circuits of the brain in this manner has resulted in consideration of use of this surgical strategy for other neurodegenerative and neuropsychiatric disorders involving non-motor circuits, including appetite, mood, and cognition...
October 14, 2016: Current Alzheimer Research
S H Bookbinder, C J Brainerd
False memories are influenced by a variety of factors, but emotion is a variable of special significance, for theoretical and practical reasons. Interestingly, emotion's effects on false memory depend on whether it is embedded in the content of to-be-remembered events or in our moods, where mood is an aspect of the context in which events are encoded. We sketch the theoretical basis for this content-context dissociation and then review accumulated evidence that content and context effects are indeed different...
October 17, 2016: Psychological Bulletin
L H Dünnweber, R Rödl, G Gosheger, F M Schiedel
Although clear advances have been made during the last 5 years, practical difficulties persist for patients and surgeons in procedures for intramedullary lengthening of long bones. In particular, precise adjustment of the desired amount of lengthening and technically reliable checking of the length actually achieved are problematic. An intramedullary nail with a new type of drive that exploits the shape memory effect has been constructed. The drive technology and the behavior of the intramedullary nail in situ were evaluated in a cadaver experiment...
October 10, 2016: Medical Engineering & Physics
Athanasios Ch Mitropoulos, Evangelos P Favvas, Konstantinos L Stefanopoulos, Etienne F Vansant
Everett's theorem-6 of the domain theory was examined by conducting adsorption in situ with small angle x-ray scattering (SAXS) supplemented by the contrast matching technique. The study focuses on the spectrum differences of a point to which the system arrives from different scanning paths. It is noted that according to this theorem at a common point the system has similar macroscopic properties. Furthermore it was examined the memory string of the system. We concluded that opposite to theorem-6: a) at a common point the system can reach in a finite (not an infinite) number of ways, b) a correction for the thickness of the adsorbed film prior to capillary condensation is necessary, and c) the scattering curves although at high-Q values coincide, at low-Q values are different indicating different microscopic states...
2016: PloS One
Simin Soleimanifar, Zahra Jafari, Masoud Motasaddi Zarandy, Houman Asadi, Hamid Haghani
INTRODUCTION: Children with cochlear implants (CIs) may experience few opportunities for positive musical experiences, and musical perception is therefore often not sufficiently developed. This paper investigates and discusses the relationship between intelligence quotient (IQ) and musical ability in children with CIs compared with children with normal hearing. MATERIALS AND METHODS: This was a comparative analytical study conducted in 48 children with unilateral CI and 48 normal-hearing children, 6-8 years of age, with 'normal' IQ and no formal music training...
September 2016: Iranian Journal of Otorhinolaryngology
Mina Taghipour, Golnar Eftekhari, Zahra Haddadian, Roham Mazloom, Mohammad Mani, Ali R Mani
Sepsis, and other causes of acute systemic inflammation, can reduce heart rate variability (HRV) and increase cardiac cycle regularity in mammals. Thus, HRV monitoring has been used for early detection of sepsis in adults and neonates. Liver cirrhosis is associated with reduced basal HRV and the development of tolerance to the cardiac chronotropic effects of bacterial endotoxin. This may pose limitations on the use of heart rate monitoring in early detection of sepsis in this patient population. In a study to develop a physiomarker for the detection of sepsis in cirrhosis, we observed that endotoxin administration in adult cirrhotic rats leads to the development of transient heart rate decelerations, a phenomenon which has been reported in neonates with sepsis, and quantified using sample asymmetry analysis...
October 13, 2016: Physiological Measurement
Lindsey Edwards, Lynne Aitkenhead, Dawn Langdon
OBJECTIVE: This study aimed to establish the relationship between short-term memory capacity and reading skills in adolescents with cochlear implants. METHODS AND MATERIALS: A between-groups design compared a group of young people with cochlear implants with a group of hearing peers on measures of reading, and auditory and visual short-term memory capacity. The groups were matched for non-verbal IQ and age. The adolescents with cochlear implants were recruited from the Cochlear Implant Programme at a specialist children's hospital...
November 2016: International Journal of Pediatric Otorhinolaryngology
Erin M Lee, Kathryn Smith, Ken Gall, Barbara D Boyan, Zvi Schwartz
Microscale surface roughness has been shown to enhance osseointegration of titanium implants through increased osteoblast differentiation while osteoblast proliferation remains greater on smooth titanium. Taking advantage of these phenomena, we developed a shape memory (meth)acrylate copolymer with thermomechanical properties that created a time-dependent dynamic surface change from smooth to rough under in vitro cell culture conditions and evaluated the effect of the shape recovery on osteoblast response...
December 2016: Biomaterials
Steven G Kohama, Lauren Renner, Noelle Landauer, Alison R Weiss, Henryk F Urbanski, Byung Park, Mary Lou Voytko, Martha Neuringer
: Studies of the effect of hormone therapy on cognitive function in menopausal women have been equivocal, in part due to differences in the type and timing of hormone treatment. Here we cognitively tested aged female rhesus macaques on (1) the delayed response task of spatial working memory, (2) a visuospatial attention task that measured spatially and temporally cued reaction times, and (3) a simple reaction time task as a control for motor speed. After task acquisition, animals were ovariectomized (OVX)...
October 5, 2016: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
Xiaobo Hu, Jing Zhou, Mohammad Vatankhah-Varnosfaderani, William F M Daniel, Qiaoxi Li, Aleksandr P Zhushma, Andrey V Dobrynin, Sergei S Sheiko
Shapeshifting enables a wide range of engineering and biomedical applications, but until now transformations have required external triggers. This prerequisite limits viability in closed or inert systems and puts forward the challenge of developing materials with intrinsically encoded shape evolution. Herein we demonstrate programmable shape-memory materials that perform a sequence of encoded actuations under constant environment conditions without using an external trigger. We employ dual network hydrogels: in the first network, covalent crosslinks are introduced for elastic energy storage, and in the second one, temporary hydrogen-bonds regulate the energy release rate...
2016: Nature Communications
J Ellart, B Chaput, J-L Grolleau
Tuberous breast deformity is a congenital breast anomaly with different clinical signs. The most consistent sign is the constricting ring at the base of the breast. There is deficiency in the horizontal and/or vertical dimensions of the breast and often herniation of breast parenchyma toward the nipple-areola complex with areola enlargement. Breast asymmetry is frequently associated. This anomaly occurs only in females, during breast development at puberty. The incidence is unknown because of minor forms more difficult to diagnose...
October 2016: Annales de Chirurgie Plastique et Esthétique
Naoyuki Himi, Hisashi Takahashi, Naohiko Okabe, Emi Nakamura, Takashi Shiromoto, Kazuhiko Narita, Tomoshige Koga, Osamu Miyamoto
BACKGROUND: Exercise in the early stage after stroke onset has been shown to facilitate the recovery from physical dysfunction. However, the mechanism of recovery has not been clarified. In this study, the effect of exercise on spatial memory function recovery in the early stage was shown, and the mechanism of recovery was discussed using a rat model of brain embolism. METHODS: Intra-arterial microsphere (MS) injection induced small emboli in the rat brain. Treadmill exercise was started at 24 hours (early group) or 8 days (late group) after MS injection...
September 14, 2016: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
Artur Turek, Edyta Olakowska, Aleksandra Borecka, Henryk Janeczek, Michał Sobota, Joanna Jaworska, Bożena Kaczmarczyk, Bożena Jarząbek, Arkadiusz Gruchlik, Marcin Libera, Arkadiusz Liśkiewicz, Halina Jędrzejowska-Szypułka, Janusz Kasperczyk
PURPOSE: Estradiol (E2)-loaded poly(L-lactide-co-glycolide-trimethylenecarbonate) (P(L-LA:GA:TMC)) rods with shape-memory were developed for the treatment of neurodegenerative diseases. Usefulness of the extrusion method in the obtaining process was also considered. The influence of structural and surface properties during hydrolytic degradation was developed. The possible therapeutic aspect of rods with E2 was determined. METHODS: The extruded rods were incubated in a PBS solution (pH 7...
September 14, 2016: Pharmaceutical Research
Kumar C Shah, Young R Seo, Benjamin M Wu
An innovative abutment system has recently been developed to address the well-known limitations of screw- and cement-retained implant restorations. This abutment system offers retrievability by replacing the cement layer with a precision-engineered nickel-titanium sleeve that switches between shapes that lock and unlock the prosthesis. The avoidance of cement precludes cement-related periimplant complications, while the elimination of occlusal screw access holes may enable predictable control over occlusion and improve the structural integrity of the prosthesis...
September 9, 2016: Journal of Prosthetic Dentistry
Dustin M Simon, Hamid Charkhkar, Conan St John, Sakthi Rajendran, Tong Kang, Radu Reit, David Arreaga-Salas, Daniel G McHail, Gretchen L Knaack, Andrew Sloan, Dane Grasse, Theodore C Dumas, Robert L Rennaker, Joseph J Pancrazio, Walter E Voit
Intracortical probe technology, consisting of arrays of microelectrodes, offers a means of recording the bioelectrical activity from neural tissue. A major limitation of existing intracortical probe technology pertains to limited lifetime of 6 months to a year of recording after implantation. A major contributor to device failure is widely believed to be the interfacial mechanical mismatch of conventional stiff intracortical devices and the surrounding brain tissue. We describe the design, development and demonstration of a novel functional intracortical probe technology that has a tunable Young's modulus from ∼2 GPa to ∼50 MPa...
September 12, 2016: Journal of Biomedical Materials Research. Part A
Evi Jacobs, Margreet C Langereis, Johan H M Frijns, Rolien H Free, Andre Goedegebure, Cas Smits, Robert J Stokroos, Saskia A M Ariens-Meijer, Emmanuel A M Mylanus, Anneke M Vermeulen
BACKGROUND: Impaired auditory speech perception abilities in deaf children with hearing aids compromised their verbal intelligence enormously. The availability of unilateral cochlear implantation (CI) auditory speech perception and spoken vocabulary enabled them to reach near ageappropriate levels. This holds especially for children in spoken language environments. However, speech perception in complex listening situations and the acquisition of complex verbal skills remains difficult...
November 2016: Research in Developmental Disabilities
Norbert Zanker, Diane Schuster, James Gilkerson, Kenneth Stein
AIM: The aim of this study was to summarize how implantable cardioverter defibrillators (ICDs) by Boston Scientific sense, detect, discriminate rhythms, and classify episodes. METHODS: Modern devices include multiple programming selections, diagnostic features, therapy options, memory functions, and device-related history features. Device operation includes logical steps from sensing, detection, discrimination, therapy delivery to history recording. The program is designed to facilitate the application of the device algorithms to the individual patient's clinical needs...
September 2016: Herzschrittmachertherapie & Elektrophysiologie
Katelyn L Black, Christine F Witty, Jill M Daniel
Ovariectomized rats that received previous administration of oestradiol in midlife display enhanced cognition and increased hippocampal levels of oestrogen receptor alpha (ERα) months after oestradiol treatment ended as compared to ovariectomized controls. Objectives of the current work were to investigate mechanisms by which ERα levels are maintained following midlife oestradiol exposure and the role of ERα in memory in aging females in the absence of circuiting oestrogens. Unliganded ERα has increased interaction with the ubiquitin ligase, C terminus of Hsc-70 interacting protein (CHIP) leading to increased degradation of the receptor...
September 7, 2016: Journal of Neuroendocrinology
Tao Gong, Kun Zhao, Xian Liu, Liuxuan Lu, Dian Liu, Shaobing Zhou
Regulation of the growth of vascular endothelial cells (ECs) and smooth muscle cells (SMCs) with artificial vascular grafts at vascularization is well-known to regenerate functional blood vessels for treating cardiovascular disease; however, little research has been published on this subject. Here, a novel polymer vascular graft is presented, whose inner surface contains an assembled circular microgroove pattern decorated with a combination of concentric circular microgrooves and radial, straight microgrooves inspired by the orientation of SMCs and ECs in natural tissues...
September 6, 2016: Small
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