keyword
MENU ▼
Read by QxMD icon Read
search

memory implant

keyword
https://www.readbyqxmd.com/read/28638591/replicable-in-vivo-physiological-and-behavioral-phenotypes-of-the-shank3b-null-mutant-mouse-model-of-autism
#1
Sameer C Dhamne, Jill L Silverman, Chloe E Super, Stephen H T Lammers, Mustafa Q Hameed, Meera E Modi, Nycole A Copping, Michael C Pride, Daniel G Smith, Alexander Rotenberg, Jacqueline N Crawley, Mustafa Sahin
BACKGROUND: Autism spectrum disorder (ASD) is a clinically and biologically heterogeneous condition characterized by social, repetitive, and sensory behavioral abnormalities. No treatments are approved for the core diagnostic symptoms of ASD. To enable the earliest stages of therapeutic discovery and development for ASD, robust and reproducible behavioral phenotypes and biological markers are essential to establish in preclinical animal models. The goal of this study was to identify electroencephalographic (EEG) and behavioral phenotypes that are replicable between independent cohorts in a mouse model of ASD...
2017: Molecular Autism
https://www.readbyqxmd.com/read/28638329/the-contribution-of-cognitive-factors-to-individual-differences-in-understanding-noise-vocoded-speech-in-young-and-older-adults
#2
Stephanie Rosemann, Carsten Gießing, Jale Özyurt, Rebecca Carroll, Sebastian Puschmann, Christiane M Thiel
Noise-vocoded speech is commonly used to simulate the sensation after cochlear implantation as it consists of spectrally degraded speech. High individual variability exists in learning to understand both noise-vocoded speech and speech perceived through a cochlear implant (CI). This variability is partly ascribed to differing cognitive abilities like working memory, verbal skills or attention. Although clinically highly relevant, up to now, no consensus has been achieved about which cognitive factors exactly predict the intelligibility of speech in noise-vocoded situations in healthy subjects or in patients after cochlear implantation...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28623139/the-co-expression-of-neogenin-with-sox2-in-hippocampal-neurons
#3
Namgue Hong, Mi-Hye Kim, Churl K Min, Hee Jung Kim, Jae Ho Lee
Dementia has been shown to be closely related with neuronal degeneration and/or a decrease in the activity of neural stem cells in many brain regions, including the hippocampus. It has been recently established that Neogenin is involved in the cell fate determination by regulating Oct3/4, SOX and Nanog, notable embryonic cell markers, expressions in pre-implantation mouse embryos. Further, Neogenin expression at both mRNA and protein levels is manifest in many brain regions in mice, but it remains unclear whether Neogenin expression is prerequisite for the maintenance of neural stem cells, particularly, playing a critical role in the hippocampus, a brain region known to be involved in memory generation and consolidation...
June 13, 2017: Biochemical and Biophysical Research Communications
https://www.readbyqxmd.com/read/28604709/two-dimensional-non-volatile-programmable-p-n-junctions
#4
Dong Li, Mingyuan Chen, Zhengzong Sun, Peng Yu, Zheng Liu, Pulickel M Ajayan, Zengxing Zhang
Semiconductor p-n junctions are the elementary building blocks of most electronic and optoelectronic devices. The need for their miniaturization has fuelled the rapid growth of interest in two-dimensional (2D) materials. However, the performance of a p-n junction considerably degrades as its thickness approaches a few nanometres and traditional technologies, such as doping and implantation, become invalid at the nanoscale. Here we report stable non-volatile programmable p-n junctions fabricated from the vertically stacked all-2D semiconductor/insulator/metal layers (WSe2/hexagonal boron nitride/graphene) in a semifloating gate field-effect transistor configuration...
June 12, 2017: Nature Nanotechnology
https://www.readbyqxmd.com/read/28585899/cognitive-functions-evaluation-and-changes-after-transcatheter-aortic-valve-implantation-in-elderly-patients
#5
Cristina Ciuca, Susy Ferrari, Lisa Placuzzi, Cinzia Marrozzini, Nevio Taglieri, Barbara Bordoni, Gianni Dall'Ara, Carolina Moretti, Michela Montefiori, Rabih Chattat, Antonio Marzocchi, Francesco Saia
AIM: To assess the prevalence and postprocedural evolution of cognitive impairment (CI) in patients undergoing transcatheter aortic valve implantation. METHODS: 62 patients were enrolled. Mini Mental state examination (MMSE), verbal memory test (VMT), visual search test (VST) and phonemic verbal fluency (PVF) were used to evaluate the cognitive status. CI was considered when a pathological result of MMSE was confirmed by VMT, VST and PVF. RESULTS: A total of 26...
June 6, 2017: Future Cardiology
https://www.readbyqxmd.com/read/28576309/bndf-heterozygosity-is-associated-with-memory-deficits-and-alterations-in-cortical-and-hippocampal-eeg-power
#6
Phillip A Geist, Brooke N Dulka, Abigail Barnes, Michael Totty, Subimal Datta
Brain derived neurotrophic factor (BDNF) plays a pivotal role in structural plasticity, learning, and memory. Electroencephalogram (EEG) spectral power in the cortex and hippocampus has also been correlated with learning and memory. In this study, we investigated the effect of globally reduced BDNF levels on learning behavior and EEG power via BDNF heterozygous (KO) rats. We employed several behavioral tests that are thought to depend on cortical and hippocampal plasticity to varying degrees: novel object recognition, a test that is reliant on a variety of cognitive systems; contextual fear, which is highly hippocampal-dependent; and cued fear, which has been shown to be amygdala-dependent...
May 31, 2017: Behavioural Brain Research
https://www.readbyqxmd.com/read/28548097/scalable-focused-ion-beam-creation-of-nearly-lifetime-limited-single-quantum-emitters-in-diamond-nanostructures
#7
Tim Schröder, Matthew E Trusheim, Michael Walsh, Luozhou Li, Jiabao Zheng, Marco Schukraft, Alp Sipahigil, Ruffin E Evans, Denis D Sukachev, Christian T Nguyen, Jose L Pacheco, Ryan M Camacho, Edward S Bielejec, Mikhail D Lukin, Dirk Englund
The controlled creation of defect centre-nanocavity systems is one of the outstanding challenges for efficiently interfacing spin quantum memories with photons for photon-based entanglement operations in a quantum network. Here we demonstrate direct, maskless creation of atom-like single silicon vacancy (SiV) centres in diamond nanostructures via focused ion beam implantation with ∼32 nm lateral precision and <50 nm positioning accuracy relative to a nanocavity. We determine the Si+ ion to SiV centre conversion yield to be ∼2...
May 26, 2017: Nature Communications
https://www.readbyqxmd.com/read/28540725/bioinspired-3d-multilayered-shape-memory-scaffold-with-a-hierarchically-changeable-micropatterned-surface-for-efficient-vascularization
#8
Dian Liu, Tao Xiang, Tao Gong, Tian Tian, Xian Liu, Shaobing Zhou
How to achieve three-dimensional (3D) cell alignment and subsequent prompt tissue regeneration remains a great challenge. Here, inspired by the interior 3D architecture of native arteries, we develop a new 3D multilayered shape memory vascular scaffold with a hierarchically changeable micropatterned surface for vascularization. The shape memory function renders the implantation of the scaffold safe and convenient via minimally invasive surgery. By co-culturing endothelial cells (ECs) and vascular smooth muscle cells (VSMCs) on the 3D multilayered structure, the inner monolayer, which has a square micropatterned surface, can promote EC adhesion and migration, resulting in a rapid endothelialization, and the outer multilayers, which have rectangular micropatterned surfaces, can induce a circumferential alignment of VSMCs...
June 2, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28506442/boosting-syntax-training-with-temporally-regular-musical-primes-in-children-with-cochlear-implants
#9
N Bedoin, A-M Besombes, E Escande, A Dumont, P Lalitte, B Tillmann
OBJECTIVES: Previous research has suggested the use of rhythmic structures (implemented in musical material) to improve linguistic structure processing (i.e., syntax processing), in particular for populations showing deficits in syntax and temporal processing (e.g., children with developmental language disorders). The present study proposes a long-term training program to improve syntax processing in children with cochlear implants, a population showing syntax processing deficits in perception and production...
May 11, 2017: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/28478769/long-term-outcome-after-percutaneous-closure-of-persistent-left-superior-caval-vein-draining-into-the-left-atrium-a-contrast-enhanced-ct-study
#10
Davide Marini, Matteo Castagno, Michele Millesimo, Francesca Ferroni, Gaetana Ferraro, Carlo Pace Napoleone, Gabriella Agnoletti
BACKGROUND: Data regarding long-term outcome after percutaneous closure of left superior caval vein draining into the left atrium are lacking. The aim of the present study was to report the long-term follow-up by using contrast-enhanced CT. METHODS: In all, three patients underwent percutaneous closure of left superior caval vein draining into the left atrium between 2005 and 2015. All of them were evaluated clinically and underwent contrast-enhanced CT. RESULTS: In one patient, the Amplatzer® Septal Occluder was used...
May 8, 2017: Cardiology in the Young
https://www.readbyqxmd.com/read/28434860/direct-brain-stimulation-modulates-encoding-states-and-memory-performance-in-humans
#11
Youssef Ezzyat, James E Kragel, John F Burke, Deborah F Levy, Anastasia Lyalenko, Paul Wanda, Logan O'Sullivan, Katherine B Hurley, Stanislav Busygin, Isaac Pedisich, Michael R Sperling, Gregory A Worrell, Michal T Kucewicz, Kathryn A Davis, Timothy H Lucas, Cory S Inman, Bradley C Lega, Barbara C Jobst, Sameer A Sheth, Kareem Zaghloul, Michael J Jutras, Joel M Stein, Sandhitsu R Das, Richard Gorniak, Daniel S Rizzuto, Michael J Kahana
People often forget information because they fail to effectively encode it. Here, we test the hypothesis that targeted electrical stimulation can modulate neural encoding states and subsequent memory outcomes. Using recordings from neurosurgical epilepsy patients with intracranially implanted electrodes, we trained multivariate classifiers to discriminate spectral activity during learning that predicted remembering from forgetting, then decoded neural activity in later sessions in which we applied stimulation during learning...
May 8, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28417536/stretchable-and-soft-electronics-using-liquid-metals
#12
REVIEW
Michael D Dickey
The use of liquid metals based on gallium for soft and stretchable electronics is discussed. This emerging class of electronics is motivated, in part, by the new opportunities that arise from devices that have mechanical properties similar to those encountered in the human experience, such as skin, tissue, textiles, and clothing. These types of electronics (e.g., wearable or implantable electronics, sensors for soft robotics, e-skin) must operate during deformation. Liquid metals are compelling materials for these applications because, in principle, they are infinitely deformable while retaining metallic conductivity...
April 18, 2017: Advanced Materials
https://www.readbyqxmd.com/read/28417025/dorsal-phalloplasty-to-preserve-penis-length-after-penile-prosthesis-implantation
#13
Osama Shaeer, Kamal Shaeer, Islam A Rahman
OBJECTIVES: Following penile prosthesis implantation (PPI), patients may complain of a decrease in visible penis length. A dorsal phalloplasty defines the penopubic junction by tacking pubic skin to the pubis, revealing the base of the penis. This study aimed to evaluate the efficacy of a dorsal phalloplasty in increasing the visible penis length following PPI. METHODS: An inflatable penile prosthesis was implanted in 13 patients with severe erectile dysfunction (ED) at the Kamal Shaeer Hospital, Cairo, Egypt, from January 2013 to May 2014...
February 2017: Sultan Qaboos University Medical Journal
https://www.readbyqxmd.com/read/28396399/context-dependent-spatially-periodic-activity-in-the-human-entorhinal-cortex
#14
Zoltan Nadasdy, T Peter Nguyen, Ágoston Török, Jason Y Shen, Deborah E Briggs, Pradeep N Modur, Robert J Buchanan
The spatially periodic activity of grid cells in the entorhinal cortex (EC) of the rodent, primate, and human provides a coordinate system that, together with the hippocampus, informs an individual of its location relative to the environment and encodes the memory of that location. Among the most defining features of grid-cell activity are the 60° rotational symmetry of grids and preservation of grid scale across environments. Grid cells, however, do display a limited degree of adaptation to environments. It remains unclear if this level of environment invariance generalizes to human grid-cell analogs, where the relative contribution of visual input to the multimodal sensory input of the EC is significantly larger than in rodents...
April 25, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28396186/-eight-days-of-nightmares-%C3%A2-octogenarian-patients-experiences-of-postoperative-delirium-after-transcatheter-or-surgical-aortic-valve-replacement
#15
Irene Instenes, Eva Gjengedal, Leslie S P Eide, Karel K J Kuiper, Anette H Ranhoff, Tone M Norekvål
BACKGROUND: Surgical aortic valve replacement (SAVR) and transcatheter aortic valve implantation (TAVI) are increasingly performed in octogenarian patients with severe aortic stenosis (AS), including those with high surgical risk. Postoperative delirium (PD) is a common and serious complication in older patients, characterised by reduced awareness, change in consciousness, disturbance in logical thinking and hallucinations. METHODS: To explore how octogenarian patients experienced PD, a qualitative study was conducted including five women and five men between 81 and 88 years...
March 20, 2017: Heart, Lung & Circulation
https://www.readbyqxmd.com/read/28386925/vagus-nerve-stimulation-surgical-technique-of-implantation-and-revision-and-related-morbidity
#16
REVIEW
Flavio Giordano, Anna Zicca, Carmen Barba, Renzo Guerrini, Lorenzo Genitori
Indications for vagus nerve stimulation (VNS) therapy include focal, multifocal epilepsy, drop attacks (tonic/atonic seizures), Lennox-Gastaut syndrome, tuberous sclerosis complex (TSC)-related multifocal epilepsy, and unsuccessful resective surgery. Surgical outcome is about 50-60% for seizures control, and may also improve mood, cognition, and memory. On this basis, VNS has also been proposed for the treatment of major depression and Alzheimer's' disease. The vagus nerve stimulator must be implanted with blunt technique on the left side to avoid cardiac side effects through the classic approach for anterior cervical discectomy...
April 2017: Epilepsia
https://www.readbyqxmd.com/read/28384805/speech-recognition-in-adults-with-cochlear-implants-the-effects-of-working-memory-phonological-sensitivity-and-aging
#17
Aaron C Moberly, Michael S Harris, Lauren Boyce, Susan Nittrouer
Purpose: Models of speech recognition suggest that "top-down" linguistic and cognitive functions, such as use of phonotactic constraints and working memory, facilitate recognition under conditions of degradation, such as in noise. The question addressed in this study was what happens to these functions when a listener who has experienced years of hearing loss obtains a cochlear implant. Method: Thirty adults with cochlear implants and 30 age-matched controls with age-normal hearing underwent testing of verbal working memory using digit span and serial recall of words...
April 14, 2017: Journal of Speech, Language, and Hearing Research: JSLHR
https://www.readbyqxmd.com/read/28377210/similar-patterns-of-neural-activity-predict-memory-function-during-encoding-and-retrieval
#18
James E Kragel, Youssef Ezzyat, Michael R Sperling, Richard Gorniak, Gregory A Worrell, Brent M Berry, Cory Inman, Jui-Jui Lin, Kathryn A Davis, Sandhitsu R Das, Joel M Stein, Barbara C Jobst, Kareem A Zaghloul, Sameer A Sheth, Daniel S Rizzuto, Michael J Kahana
Neural networks that span the medial temporal lobe (MTL), prefrontal cortex, and posterior cortical regions are essential to episodic memory function in humans. Encoding and retrieval are supported by the engagement of both distinct neural pathways across the cortex and common structures within the medial temporal lobes. However, the degree to which memory performance can be determined by neural processing that is common to encoding and retrieval remains to be determined. To identify neural signatures of successful memory function, we administered a delayed free-recall task to 187 neurosurgical patients implanted with subdural or intraparenchymal depth electrodes...
April 2, 2017: NeuroImage
https://www.readbyqxmd.com/read/28362398/automatic-detection-of-highly-organized-theta-oscillations-in-the-murine-eeg
#19
Ralf Müller, Anna Papazoglou, Julien Soos, Andreas Lundt, Carola Wormuth, Christina Henseler, Dan Ehninger, Karl Broich, Marco Weiergräber
Theta activity is generated in the septohippocampal system and can be recorded using deep intrahippocampal electrodes and implantable electroencephalography (EEG) radiotelemetry or tether system approaches. Pharmacologically, hippocampal theta is heterogeneous (see dualistic theory) and can be differentiated into type I and type II theta. These individual EEG subtypes are related to specific cognitive and behavioral states, such as arousal, exploration, learning and memory, higher integrative functions, etc...
March 10, 2017: Journal of Visualized Experiments: JoVE
https://www.readbyqxmd.com/read/28341611/extinction-memory-is-facilitated-by-methylphenidate-and-regulated-by-dopamine-and-noradrenaline-receptors
#20
Cristiane R G Furini, Jonny A K Behling, Carolina G Zinn, Mara Lise Zanini, Eduardo Assis Brasil, Luiza Doro Pereira, Ivan Izquierdo, Jociane de Carvalho Myskiw
Extinction is defined as the learned inhibition of retrieval and is the mainstay of exposure therapy, which is widely used to treat drug addiction, phobias and fear disorders. The psychostimulant, methylphenidate (MPH) is known to increase extracellular levels of noradrenaline and dopamine by blocking their reuptake and studies have demonstrated that MPH can modulate hippocampal physiology and/or functions including long-term potentiation (LTP), learning and memory. However, the influence of MPH on fear extinction memory has been insufficiently studied...
March 21, 2017: Behavioural Brain Research
keyword
keyword
57003
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"