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https://www.readbyqxmd.com/read/29451184/the-long-term-outcomes-of-cirrhotic-patients-with-pleural-effusion
#1
Tsung-Hsing Hung, Chih-Wei Tseng, Chih-Chun Tsai, Chen-Chi Tsai, Kuo-Chih Tseng, Yu-Hsi Hsieh
Background/Aim: A pleural effusion is an abnormal collection of fluid in the pleural space and may cause related morbidity or mortality in cirrhotic patients. Currently, there are insufficient data to support the long-term prognosis for cirrhotic patients with pleural effusion. In this study, we investigated the short- and long-term effects of pleural effusion on mortality in cirrhotic patients and evaluated the benefit of liver transplantation in these patients. Patients and Methods: The National Health Insurance Database, derived from the Taiwan National Health Insurance Program, was used to identify 3,487 cirrhotic patients with pleural effusion requiring drainage between January 1, 2007 and December 31, 2010...
January 2018: Saudi Journal of Gastroenterology: Official Journal of the Saudi Gastroenterology Association
https://www.readbyqxmd.com/read/29439066/effect-of-an-increased-dosage-of-statins-on-spinal-degenerative-joint-disease-a-retrospective-cohort-study
#2
Yuan-Yang Cheng, Chung-Lan Kao, Shih-Yi Lin, Shin-Tsu Chang, Tz-Shiang Wei, Shih-Ni Chang, Ching-Heng Lin
OBJECTIVES: It has been proven that statin can protect synovial joints from developing osteoarthritis through its anti-inflammatory effects. However, studies on the effect of statins on spinal degenerative joint diseases are few and limited to in vitro studies. Therefore, we investigated the relationship between the statin dosage and the development of spinal degenerative joint diseases. DESIGN: A retrospective cohort study. SETTING: Patients registered in Taiwan National Health Insurance Research Database...
February 8, 2018: BMJ Open
https://www.readbyqxmd.com/read/29437757/sexual-inequality-in-incident-tuberculosis-a-cohort-study-in-taiwan
#3
Yung-Feng Yen, Hsiao-Yun Hu, Ya-Ling Lee, Po-Wen Ku, Ming-Chung Ko, Pei-Hung Chuang, Yun-Ju Lai, Dachen Chu
OBJECTIVE: Animal studies showed that male subjects had lower activity of immune response to infections than female subjects, which may increase the risk of the development of tuberculosis in male population. This study intended to investigate the risk of incident tuberculosis in male and female adults in Taiwan. DESIGN: This is a retrospective cohort study. SETTING: The present analyses used data of Taiwan National Health Interview Survey 2001, 2005 and 2009, National Register of Deaths Dataset, and National Health Insurance Research Database from 2000 to 2013...
February 6, 2018: BMJ Open
https://www.readbyqxmd.com/read/29435184/dipyridamole-decreases-dialysis-risk-and-improves-survival-in-patients-with-pre-dialysis-advanced-chronic-kidney-disease
#4
Ko-Lin Kuo, Szu-Chun Hung, Wei-Cheng Tseng, Jia-Sin Liu, Ming-Huang Lin, Chih-Cheng Hsu, Der-Cherng Tarng
Introduction: Dipyridamole decreases proteinuria and improves renal function progression in patients with glomerular disease through its inhibition of platelet activation and enhanced nitric oxide expression. Few studies have evaluated the effects of dipyridamole on renal outcome or survival in CKD stage 5 patients who have not yet received dialysis (CKD 5 ND). Materials and Methods: A prospective cohort study was conducted based on the Taiwan National Health Insurance Research Database...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29435177/prostate-selective-%C3%AE-antagonists-increase-fracture-risk-in-prostate-cancer-patients-with-and-without-a-history-of-androgen-deprivation-therapy-a-nationwide-population-based-study
#5
Wei-Heng Kao, Chang-Fu Kuo, I-Jun Chou, Lai-Chu See, Wen-Kuan Huang, Meng-Jiun Chiou, Weiya Zhang, Michael Doherty, Chun-Chieh Wang, Jun-Te Hsu, Hsien-Hsin Chen, Ji-Hong Hong
Introductions: Prostate-selective α antagonists are recommended for relief of lower urinary tract symptoms in prostate cancer patients despite uncertainty of fracture risk as an addition to androgen deprivation therapy (ADT). The purpose of this study is to estimate fracture risk associated with these medications in prostate cancer patients who did and did not receive ADT. Methods: The Taiwan National Health Insurance database was used to identify prostate cancer patients...
January 12, 2018: Oncotarget
https://www.readbyqxmd.com/read/29432960/use-of-ics-laba-combinations-or-lama-is-associated-with-a-lower-risk-of-acute-exacerbation-in-patients-with-coexistent-copd-and-asthma
#6
Vincent Yi-Fong Su, Kuang-Yao Yang, Yao-Hsu Yang, Ying-Huang Tsai, Diahn-Warng Perng, Wei-Juin Su, Kun-Ta Chou, Kang-Cheng Su, Yung-Feng Yen, Pau-Chung Chen
BACKGROUND: Based on current guidelines, more research is urgently needed to guide appropriate treatment for patients with asthma-chronic obstructive pulmonary disease overlap. OBJECTIVE: The objective of this study was to investigate medication effects on acute exacerbation in patients with coexistent COPD and asthma. METHODS: Using Taiwan's National Health Insurance Research Database, we conducted a nationwide population-based study to evaluate medication effects in patients with COPD and asthma...
February 9, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29428977/sleep-disorders-associated-with-risk-of-rheumatoid-arthritis
#7
Wei-Sheng Chung, Cheng-Li Lin
BACKGROUND: Immune disorders impair sleep quality and sleep disorders (SDs) may derange immune function. PURPOSE: The study evaluated the incidence and risk of rheumatoid arthritis (RA) in patients with SDs using a nationwide cohort. METHODS: We recognized the patients with SDs from 1998 to 2002 by using the Taiwan National Health Insurance Research Database. One control patient for each SD patient was randomly selected and matched based on the proportion of age, sex, and index year...
February 10, 2018: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/29428194/malignant-transformation-of-taiwanese-patients-with-oral-leukoplakia-a-nationwide-population-based-retrospective-cohort-study
#8
Tung-Yuan Wang, Yu-Wei Chiu, Yi-Tzu Chen, Yu-Hsun Wang, Hui-Chieh Yu, Chuan-Hang Yu, Yu-Chao Chang
BACKGROUND/PURPOSE: Oral leukoplakia (OL) is one of the clinically diagnosed oral potentially malignant disorders (OPMDs) with an increased risk of oral cancer development. In this study, we investigated the malignant transformation of OL in Taiwanese population. METHODS: A retrospective cohort study was analyzed from Taiwan's National Health Insurance Research Database. A comparison cohort was randomly frequency-matched with the OL cohort according to age, sex, and index year...
February 7, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
https://www.readbyqxmd.com/read/29426752/increased-dose-and-duration-of-statin-use-is-associated-with-decreased-asthma-related-emergency-department-visits-and-hospitalizations
#9
Jiu-Yao Wang, Tsung-Chieh Yao, Yu-Ting Tsai, Ann Chen Wu, Hui-Ju Tsai
BACKGROUND: Statins have pleiotropic anti-inflammatory and immunomodulatory effects, yet the effect of statin use on asthma-related emergency department (ED) visits and hospitalizations has remained unclear, especially in Asian populations. OBJECTIVE: We sought to examine the effect of statin therapy on asthma-related ED visits and/or hospitalizations. METHODS: A cohort study was conducted using data from Taiwan's National Health Insurance Research Database from 2001 to 2013...
February 6, 2018: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/29425665/newly-diagnosed-bipolar-disorder-and-the-subsequent-risk-of-erectile-dysfunction-a-nationwide-cohort-study
#10
Po-Hsun Hou, Frank Chiahung Mao, Geng-Ruei Chang, Min-Wei Huang, Yao-Ting Wang, Shiau-Shian Huang
BACKGROUND: Although erectile dysfunction (ED) is a common problem in men with mental disorders, there are few reports in the literature on the relation between bipolar disorder (BD) and ED. AIMS: To establish the incidence rate of ED in men with BD and assess the risk of ED in patients with BD according to type of treatment offered or no active treatment with medication during the 1st year of onset. METHODS: We identified 5,150 men with newly diagnosed BD using Taiwan's National Health Insurance Research Database...
February 2018: Journal of Sexual Medicine
https://www.readbyqxmd.com/read/29424065/trend-and-outcome-of-sepsis-in-children-a-nationwide-cohort-study
#11
Chia-Hung Yo, Tzu-Chun Hsu, Meng-Tse Gabriel Lee, Lorenzo Porta, Po-Yang Tsou, Yu-Hsun Wang, Wan-Chien Lee, Szu-Ta Chen, Chien-Chang Lee
AIM: The aim of this study was to investigate the trend of incidence and outcome of paediatric sepsis in a population-based database. METHODS: Children with sepsis were identified from the 23 million nationwide health insurance claims database of Taiwan. Sepsis was defined by the presence of single ICD-9 code for severe sepsis or septic shock or a combination of ICD-9 codes for infection and organ dysfunction. We analysed the trend of incidence, mortality and source of infection in three age groups: infant (28 days to 1 year), child (1-9 years) and adolescent (10-18 years)...
February 9, 2018: Journal of Paediatrics and Child Health
https://www.readbyqxmd.com/read/29420551/survival-factors-of-hospitalized-out-of-hospital-cardiac-arrest-patients-in-taiwan-a-retrospective-study
#12
Chung-Yu Lai, Fu-Huang Lin, Hsin Chu, Chih-Hung Ku, Shih-Hung Tsai, Chi-Hsiang Chung, Wu-Chien Chien, Chun-Hsien Wu, Chi-Ming Chu, Chi-Wen Chang
The chain of survival has been shown to improve the chances of survival for victims of cardiac arrest. Post-cardiac arrest care has been demonstrated to significantly impact the survival of out-of-hospital cardiac arrest (OHCA). How post-cardiac arrest care influences the survival of OHCA patients has been a main concern in recent years. The objective of this study was to assess the survival outcome of hospitalized OHCA patients and determine the factors associated with improved survival in terms of survival to discharge...
2018: PloS One
https://www.readbyqxmd.com/read/29419706/rehabilitation-reduced-readmission-and-mortality-risks-in-patients-with-stroke-or-transient-ischemic-attack-a-population-based-study
#13
Ku-Chou Chang, Jen-Wen Hung, Hsuei-Chen Lee, Chu-Ling Yen, Ching-Yi Wu, Chung-Lin Yang, Yu-Ching Huang, Pei-Li Lin, Hui-Hsuan Wang
BACKGROUND: It remains unclear whether rehabilitation has an impact on reducing the long-term risk of mortality or readmission following stroke or transient ischemic attack (TIA). OBJECTIVES: To investigate the association between the dosage and continuation of rehabilitation and the risk of outcome events (OEs) after stroke or TIA. RESEARCH DESIGN: A retrospective cohort study using Taiwan's National Health Insurance database. SUBJECTS: In total, 4594 patients admitted with first-ever acute stroke or TIA were followed-up for 32 months...
February 6, 2018: Medical Care
https://www.readbyqxmd.com/read/29419688/impact-of-dialysis-dependence-on-prognosis-in-patients-with-myocardial-infarction-an-11-year-population-based-study
#14
Chung-Ming Fu, Chih-Hsiang Chang, Cheng-Chia Lee, Pei-Chun Fan, Shao-Wei Chen, Chien-Te Lee, Chien-Hsing Wu, Lung-Chih Li, Tien-Hsing Chen
In this study we aimed to directly compare the short and long-term prognosis of nondialysis patients with chronic kidney disease (CKD), dialysis patients, and patients with preserved renal function after acute myocardial infarction (AMI).AMI in patients with CKD is a catastrophic event associated with high medical expenditures and dismal survival. However, there is little research comparing post-AMI outcomes between patients with CKD who were and were not receiving dialysis.The retrospective cohort study included patients with AMI (n = 158,125) in the Taiwan's National Health Insurance Research Database who were treated March 1998 and December 2009...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29419677/risk-of-major-comorbidities-among-workers-with-hemophilia-a-14-year-population-based-study
#15
Wei-Min Chu, Hsin-En Ho, Jiaan-Der Wang, Wei-Cheng Chan, Yi-Sheng Liou, Wen-Chao Ho, Sung-Yuan Hu, Yu-Tse Tsan
Multiple comorbidities, especially musculoskeletal dysfunction and cerebrovascular disease, remain barriers to normal social participation among persons with hemophilia (PWH). However, the relative health effects of such comorbidities on workers with hemophilia have seldom been explored. In this study, we investigated the incidence of comorbidities and their risk factors among workers with hemophilia.The study compared the incidence and risk factors of the major comorbidities of 411 workers with hemophilia enrolled in Taiwan's National Health Insurance Research Database between 1997 and 2010 with an age- and sex-matched general population...
February 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29416815/increased-risk-of-malignancy-in-patients-with-an-aortic-aneurysm-a-nationwide-population-based-retrospective-study
#16
Jen-Chun Wang, Wu-Chien Chien, Chi-Hsiang Chung, Wen-I Liao, Chang-Huei Tsao, Yung-Fu Wu, Shih-Hung Tsai
Background: Cardiovascular disease and malignancy have numerous similarities and possible interactions, as these diseases share several risk factors, epidemiological features and biological signaling pathways. Data regarding the risk of malignancy in patients with aortic aneurysm (AA) are scarce. We aimed to determine whether patients with AA have an increased risk of malignancy. Materials and Methods: The data for the nationwide population-based retrospective cohort study described herein were obtained from the Taiwan National Health Insurance Research Database (NHIRD)...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29416761/increased-risk-of-parkinson-s-disease-following-tension-type-headache-a-nationwide-population-based-cohort-study
#17
Fu-Chi Yang, Hsuan-Ju Chen, Jiunn-Tay Lee, Sy-Jou Chen, Yueh-Feng Sung, Chia-Hung Kao, Tse-Yen Yang
Purpose: Previous studies have suggested associations between primary headache and neurodegenerative diseases; however, the relationship between tension-type headache (TTH), which is the most common type of primary headache, and Parkinson's disease (PD) remains controversial. Hence, in this nationwide, population-based, retrospective cohort study, we explored the temporal association between TTH and PD. Methods: Using claims data in the National Health Insurance Research Database of Taiwan, we evaluated 12,309 subjects aged ≥20 years who were newly diagnosed with TTH from 2000 to 2005...
January 5, 2018: Oncotarget
https://www.readbyqxmd.com/read/29415688/risk-of-dementia-in-patients-with-primary-insomnia-a-nationwide-population-based-case-control-study
#18
Chao-Ming Hung, Ying-Chun Li, Han-Jung Chen, Kang Lu, Cheng-Loong Liang, Po-Chou Liliang, Yu-Duan Tsai, Kuo-Wei Wang
BACKGROUND: To investigate the association between primary insomnia and dementia using a Taiwanese population-based database. METHODS: This case-control study involved a subset of Taiwan's National Health Insurance Research Database of reimbursement claims. We included 51,734 patients who were diagnosed with primary insomnia from 2002 to 2004 as the test group and 258,715 nonprimary insomnia participants aged 20 years or older as the reference group. We excluded patients under 20 and those with depression, post-traumatic stress disorder, and/or sleep disorders caused by organic lesion(s), drugs, or alcohol...
February 7, 2018: BMC Psychiatry
https://www.readbyqxmd.com/read/29408915/comorbidity-profiles-of-psoriasis-in-taiwan-a-latent-class-analysis
#19
Chen-Yi Wu, Hsiao-Yun Hu, Chung-Pin Li, Yiing-Jeng Chou, Yun-Ting Chang
BACKGROUND: Psoriasis is associated with many comorbidities. An understanding of these comorbidity patterns can help foster better care of patients with psoriasis. OBJECTIVE: To identify the heterogeneity of psoriasis comorbidities using latent class analysis (LCA). METHODS: LCA was used to empirically identify psoriasis comorbidity patterns in a nationwide sample of 110,729 incident cases of psoriasis (2002-2012) from the National Health Insurance database in Taiwan...
2018: PloS One
https://www.readbyqxmd.com/read/29407535/change-in-1-year-hospitalization-of-overall-and-older-patients-with-major-depressive-disorder-after-second-generation-antipsychotics-augmentation-treatment
#20
Chun-Yuan Lin, Te-Jen Lai, Yu-Hsin Wu, Ping-Kun Chen, Yuan-Fu Lin, I-Chia Chien
BACKGROUND: Studies on second-generation antipsychotics (SGA) augmentation treatment for older adults with major depressive disorder (MDD) remain limited. We aimed to investigate the effectiveness of SGA augmentation for overall and older patients with MDD inpatient history by assessing the change in 1-year hospitalization before and after SGA augmentation using the latest National Health Insurance Research Database (NHIRD) in Taiwan. METHODS: The samples were MDD patients (ICD-9 CM code: 296...
January 31, 2018: Journal of Affective Disorders
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