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national health insurance database taiwan

Chi-Chen Wu, Ching-Heng Lin, Han-Sun Chiang, Ming-Je Tang
BACKGROUND: Disparities in prostate cancer (PCa) outcomes and their links to socioeconomic status (SES) have been intensively studied. A relatively low incidence rate and a high proportion of late-stage diagnosis have been documented in studies of Asian populations. For the past 20 years, the trend in the growth of PCa cases in Taiwan was opposite to that of Western countries. However, there is a striking paucity of local studies on these important issues. To mitigate this gap in knowledge, we exploited two population databases to investigate the impact of SES on PCa incidence rate and stage at diagnosis...
June 15, 2018: International Journal for Equity in Health
Yao-Te Tsai, Ethan I Huang, Geng-He Chang, Ming-Shao Tsai, Cheng-Ming Hsu, Yao-Hsu Yang, Meng-Hung Lin, Chia-Yen Liu, Hsueh-Yu Li
OBJECTIVE: Studies have revealed that 3.5%-26.6% of patients with epiglottitis have comorbid diabetes mellitus (DM). However, whether preexisting DM is a risk factor for acute epiglottitis remains unclear. In this study, our aim was to explore the relationship between preexisting DM and acute epiglottitis in different age and sex groups by using population-based data in Taiwan. METHODS: We analyzed data between January 2000 and December 2013 obtained from the Taiwan National Health Insurance Research Database...
2018: PloS One
Shu-Chen Kuo, Shu-Man Shih, Tsai-Ling Yang Lauderdale, I-Shou Chang, Yee-Chun Chen, Chao A Hsiung, Shang-Chwen Chang
OBJECTIVE: A policy initiated in 2001 by Taiwan's National Health Insurance (NHI) Administration has effectively reduced outpatient antibiotic use except fluoroquinolones (FQs). The influence of differential regulation policy of narrow-spectrum versus broad-spectrum FQs on the prescriptions is unknown. METHODS: This study analyzed the claim records of oral FQs prescription at outpatient visits during 2000-2010 using the NHI Research Database and compared prescriptions for narrow-spectrum FQs, which are inactive against Streptococcus pneumoniae and lack formulary restriction, with those for broad-spectrum FQs...
May 29, 2018: Journal of Microbiology, Immunology, and Infection, Wei Mian Yu Gan Ran za Zhi
Victor Chien-Chia Wu, Shang-Hung Chang, Chang-Fu Kuo, Jia-Rou Liu, Shao-Wei Chen, Yung-Hsin Yeh, Shue-Fen Luo, Lai-Chu See
BACKGROUND: The literature on suicide mortality rates in patients with cardiovascular diseases (CVDs) is limited. METHODS: Taiwan National Health Insurance Research Database and Taiwan Death Registry were retrieved for patients with the 5 CVDs: congestive heart failure (CHF), acute myocardial infarction (AMI), ischemic stroke (IS), hemorrhagic stroke (HS), and pacemaker implantation (PMI) between January 1, 2001, and December 31, 2015. We excluded patients younger than 15 years old...
June 1, 2018: Journal of Affective Disorders
Shan-Yueh Chang, Wu-Chien Chien, Chi-Hsiang Chung, Hsin-An Chang, Yu-Chen Kao, Hui-Wen Yeh, Yu-Ching Chou, Chung-Kan Peng, Chih-Hao Shen, Nian-Sheng Tzeng
This study aimed to investigate the association between charcoal-burning suicide attempts and the risk of developing dementia. A nationwide, matched cohort, population-based study enrolled a total of 4103 patients with newly diagnosed charcoal-burning suicide attempts, between 2000 and 2010, which were selected from the National Health Insurance Research Database of Taiwan, along with 12,309 controls matched for sex and age. After adjusting for confounding factors, Fine and Gray's competing risk analysis was used to compare the risk of developing dementia during the 10-year follow-up period...
June 8, 2018: Journal of Investigative Medicine: the Official Publication of the American Federation for Clinical Research
Fu-Chao Liu, Huan-Tang Lin, Chang-Fu Kuo, Mei-Yun Hsieh, Lai-Chu See, Huang-Ping Yu
Background: Individuals with a family history of Parkinson's disease (PD) appear to have a higher risk of developing PD and other neuropsychiatric diseases. However, estimates of the relative risks (RRs) of PD and the roles of genetic and environmental factors in PD susceptibility are unclear. The aim of this study was to examine familial aggregation and genetic contributions to PD and the RRs of other neuropsychiatric diseases in relatives of PD patients. Methods: In this population-based family cohort study, the records of all individuals actively registered in the Taiwan National Health Insurance Research Database in 2015 were queried (N=24,349,599)...
2018: Clinical Epidemiology
Yu-Ling Kuo, Te-Fu Chan, Chien-Yi Wu, Chin-Ru Ker, Hung-Pin Tu
OBJECTIVE: This study aims to examine the long-term cardiovascular and cerebrovascular risks in a large cohort of women with past history of preeclampsia and/or eclampsia. MATERIALS AND METHODS: This is a retrospective longitudinal study using National Health Insurance Research Database from 1996 to 2010. We identified 1295 women with preeclampsia and eclampsia. The control group was 5180 pregnant women without preeclampsia/eclampsia, who were matched for age and date of delivery...
June 2018: Taiwanese Journal of Obstetrics & Gynecology
Chun-Ming Chen, Hsuan-Ju Chen, Wei-Shan Chen, Che-Chen Lin, Chih-Cheng Hsu, Yueh-Han Hsu
OBJECTIVE: To determine the clinical effectiveness of influenza vaccination in patients with rheumatoid arthritis (RA). METHODS: The present study was conducted by using the Taiwan National Health Insurance Research Database. In this retrospective nationwide study, we included 3748 RA patients who received influenza vaccinations in 2008, 2009 and 2010, and 3748 matched RA patients who did not receive influenza vaccinations. We followed the patients from 4 weeks after influenza vaccination to the end of the influenza season in each year...
June 2018: International Journal of Rheumatic Diseases
Chia-Lin Tsai, Jiunn-Tay Lee, Li-Ming Lien, Chun-Chieh Lin, I-Ju Tsai, Yueh-Feng Sung, Chung-Hsing Chou, Fu-Chi Yang, Chia-Kuang Tsai, I-Kuan Wang, Chun-Hung Tseng, Chung-Y Hsu
Background: Multiple sclerosis (MS) is the most common inflammatory demyelinating disease of the central nervous system. Few studies focused on the relationship between septicemia and MS. Aim: To evaluate the potential impact of septicemia on risk for MS. Design: Two cohorts of patients with septicemia and without septicemia were followed up for the occurrence of MS. Methods: 482,790 patients with septicemia was enrolled from the National Health Insurance Research Database between 2001 and 2011 as the study group to match the 1,892,820 individuals, as the control group, by age and gender...
June 6, 2018: QJM: Monthly Journal of the Association of Physicians
Chih-Hsien Liao, Ning Lu, Chao-Hsiun Tang, Hui-Chih Chang, Kuo-Cherh Huang
Background: There is still significant uncertainty as to whether market competition raises or lowers clinical quality in publicly funded healthcare systems. We attempted to assess the effects of market competition on inpatient care quality of stroke patients in a retrospective study of the universal single-payer health insurance system in Taiwan. Methods: In this 11-year population-based study, we conducted a pooled time-series cross-sectional analysis with a fixed-effects model and the Hausman test approach by utilizing two nationwide datasets: the National Health Insurance Research Database and the National Hospital and Services Survey in Taiwan...
June 4, 2018: European Journal of Public Health
Tzu-Yi Wu, Chia-Hua Chung, Chia-Ni Lin, Jing-Shiang Hwang, Jung-Der Wang
Background: The mortality rates for different cancers are no longer an efficient tool for making national policy. The purpose of this study were to quantify the lifetime risks, life expectancies (LEs) after diagnosis, expected years of life lost (EYLL), and lifetime health care expenditures for 19 major cancers in Taiwan. Methods: A total of 831,314 patients with 19 pathologically proven cancers were abstracted from the Taiwan Cancer Registry from 1998 to 2012. They were linked to the National Mortality Registry (1998-2014) and National Health Insurance reimbursement database (1998-2013) for survival and health care costs...
2018: Clinical Epidemiology
Jiunn-Horng Chen, Hsuan-Ju Chen, Chia-Hung Kao, Chun-Hung Tseng, Chon-Haw Tsai
BACKGROUND: Prior literatures have shown inflammatory bowel disease (IBD) could increase fibromyalgia (FM) risk. However, studies about gender and age distributions of FM risk among patients with IBD are rare. With large study samples, this study aimed to evaluate the FM risk among IBD patients with different gender and different age. OBJECTIVE: We aim to estimate the FM risk among male and younger IBD patients with a large patient sample. STUDY DESIGN: A retrospective cohort study was arranged in this research...
May 2018: Pain Physician
Kuan-Cheng Lai, Sy-Jou Chen, Chin-Sheng Lin, Fu-Chi Yang, Cheng-Li Lin, Chin-Wang Hsu, Wen-Chen Huang, Chia-Hung Kao
Purpose: The present study compared the risk of ischemic stroke in atrial fibrillation (AF) patients receiving digoxin and amiodarone. Methods: A retrospective cohort study was conducted using the longitudinal population-based database of Taiwan's National Health Insurance program. Patients with AF who received amiodarone or digoxin and were considered to have exposed to study drugs consecutively over 180 days during 2000-2010 were enrolled and divided into three groups: those who received amiodarone, digoxin, and amiodarone plus digoxin...
2018: Frontiers in Pharmacology
Huan-Tang Lin, Fu-Chao Liu, Jr-Rung Lin, See-Tong Pang, Huang-Ping Yu
OBJECTIVE: Most patients with uraemia must undergo chronic dialysis while awaiting kidney transplantation; however, the role of the pretransplant dialysis modality on the outcomes of kidney transplantation remains obscure. The objective of this study was to clarify the associations between the pretransplant dialysis modality, namely haemodialysis (HD) or peritoneal dialysis (PD), and the development of post-transplant de novo diseases, allograft failure and all-cause mortality for kidney-transplant recipients...
June 4, 2018: BMJ Open
Feng-Chen Kao, Yao-Chun Hsu, Pang-Yu Lai, Chang-Bi Wang, Yuan-Kun Tu, Wen-Kang Chen
BACKGROUND: Knowledge on periprosthetic infection and mortality rate following total knee arthroplasty (TKA) is essential for justifying this treatment in patients with cancer; however, relevant data from population-based studies are lacking. Therefore, we examined 1-year periprosthetic infection, mortality, and 5-year relative survival rates in cancer patients who underwent TKA. METHODS: This is a population-based cohort study based on analysis of the Taiwan National Health Insurance Research Database...
June 4, 2018: BMC Cancer
Tu-Chen Chung, Chi-Hsiang Chung, Hsuan-Ju Peng, Chang-Huei Tsao, Wu-Chien Chien, Huey-Fang Sun
Postpartum depression has become an important topic of concern in recent years. However, very few studies on the causes of postpartum depression exist, and the effects of prenatal sleep disorders on the development of postpartum depression among pregnant women have not been elucidated. This study aimed to understand the association between prenatal sleep disorders and postpartum depression. The National Health Insurance Research Database of Taiwan (between 2000 and 2010) was used to assess the effects of prenatal sleep disorder on the risk of postpartum depression using Cox regression analyses...
May 18, 2018: Oncotarget
Pei-Chien Tsai, Ta-Wei Liu, Chung-Feng Huang, Ming-Lun Yeh, Chia-Yen Dai, Wan-Long Chuang, Jee-Fu Huang, Ming-Lung Yu
BACKGROUND: A direct-acting antiviral (DAA) era in hepatitis C virus (HCV) treatment is fast approaching; unfortunately, the availability and affordability of DAAs in Asia-Pacific areas vary, making it difficult to develop universal HCV practice guidelines appropriate for the all Asian populations. This study aimed to evaluate the real-world cost-effectiveness of IFN-based therapy according to the current strategies with PegIFN/RBV for "easy-to-treat" to provide a reference for application of future DAA development for IFN-eligible, treatment naïve HCV patients...
May 31, 2018: Journal of the Chinese Medical Association: JCMA
Ching-Wen Huang, I-Hsuan Hwang, Young-Hee Yun, Bo-Hyoung Jang, Fang-Pey Chen, Shinn-Jang Hwang, Seong-Gyu Ko
BACKGROUND: As the number of people seeking to use traditional medicine to treat common diseases is increasing worldwide, the quantity of information that needs to be analyzed is also increasing. Traditional medicine is commonly used in South Korea and Taiwan for treating allergic rhinitis and is covered by the National Health Insurance in both countries. To date, there has been no nationwide comparison of traditional medicine used to treat patients with allergic rhinitis between these two countries...
May 31, 2018: Journal of the Chinese Medical Association: JCMA
Yih-Ru Chen, Fang-I Hsieh, Li-Ming Lien, Chaur-Jong Hu, Jiann-Shing Jeng, Giia-Sheun Peng, Sung-Chun Tang, Nai-Fang Chi, Yueh-Feng Sung, Hung-Yi Chiou
The effect of RA on recurrent stroke is unknown. Therefore, we examined effects of rheumatoid arthritis (RA) on risk of stroke recurrence and investigated the interaction between RA and traditional cardiovascular risk factors on recurrence risk after ischemic stroke (IS) or transient ischemic attack (TIA). Of 3190 patients with IS or TIA recruited in this cohort study, 638 were comorbid with RA and 2552 without RA. Stroke recurrence, RA, lifestyle, lipid variables and other comorbidities were identified through linkage between a nationwide stroke database in Taiwan and the National Health Insurance claims database...
June 2, 2018: Journal of Neurology
Yu-Chih Lin, Chih-Hsiang Chang, Chee-Jen Chang, Yi-Chun Wang, Pang-Hsin Hsieh, Yuhan Chang
PURPOSE: To evaluate the incidence, risk factors, mortality, and complications of direct vascular injury (VI) in patients who underwent primary total knee arthroplasty (TKA) using data from a nationwide database. METHODS: Data were collected from the National Health Insurance Research Database of Taiwan. The study group included 111,497 patients who underwent TKA from January 2004 to December 2011. In total, 15 cases of direct VI were reported (VI group). We analyzed the incidence, risk factors, mortality, complications of direct VI and hospital stays between groups (VI group and non-VI group)...
May 30, 2018: Journal of the Formosan Medical Association, Taiwan Yi Zhi
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