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https://www.readbyqxmd.com/read/28821915/risk-and-outcomes-of-fracture-in-peripheral-arterial-disease-patients-two-nationwide-cohort-studies
#1
F-L Liu, C-S Lin, C-C Yeh, C-C Shih, Y-G Cherng, C-H Wu, T-L Chen, C-C Liao
Using national insurance claims data of Taiwan, we found that patients with peripheral arterial disease (PAD) had increased risk of fracture during the follow-up period of 2000-2013. History of PAD was also associated with adverse outcomes in hospitalized fracture patients. Prevention strategies were needed in this susceptible population. INTRODUCTION: Limited information was available on the association between PAD and fracture. The purpose of this study is to evaluate fracture risk and post-fracture outcomes in patients with PAD...
August 18, 2017: Osteoporosis International
https://www.readbyqxmd.com/read/28817654/investigating-spousal-concordance-of-diabetes-through-statistical-analysis-and-data-mining
#2
Jong-Yi Wang, Chiu-Shong Liu, Chi-Hsuan Lung, Ya-Tun Yang, Ming-Hung Lin
OBJECTIVE: Spousal clustering of diabetes merits attention. Whether old-age vulnerability or a shared family environment determines the concordance of diabetes is also uncertain. This study investigated the spousal concordance of diabetes and compared the risk of diabetes concordance between couples and noncouples by using nationally representative data. METHODS: A total of 22,572 individuals identified from the 2002-2013 National Health Insurance Research Database of Taiwan constituted 5,643 couples and 5,643 noncouples through 1:1 dual propensity score matching (PSM)...
2017: PloS One
https://www.readbyqxmd.com/read/28815803/validity-of-cancer-diagnosis-in-the-national-health-insurance-database-compared-with-the-linked-national-cancer-registry-in-taiwan
#3
Wei-Heng Kao, Ji-Hong Hong, Lai-Chu See, Huang-Ping Yu, Jun-Te Hsu, I-Jun Chou, Wen-Chi Chou, Meng-Jiun Chiou, Chun-Chieh Wang, Chang-Fu Kuo
PURPOSE: We aimed to evaluate the validity of cancer diagnosis in the National Health Insurance (NHI) database, which has routinely collected the health information of almost the entire Taiwanese population since 1995, compared with the Taiwan National Cancer Registry (NCR). METHODS: There were 26,542,445 active participants registered in the NHI database between 2001 and 2012. National Cancer Registry and NHI database records were compared for cancer diagnosis; date of cancer diagnosis; and 1, 2, and 5 year survival...
August 16, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/28814359/the-risk-of-autoimmune-connective-tissue-diseases-in-patients-with-atopy-a-nationwide-population-based-cohort-study
#4
Yi-Chun Hou, Hsiao-Yun Hu, I-Lin Liu, Yun-Ting Chang, Chen-Yi Wu
BACKGROUND: The relationship between autoimmune connective tissue disease (ACTD) and atopy is controversial. OBJECTIVES: To investigate the risks of ACTDs in patients with atopic triad diseases, including atopic dermatitis, allergic rhinitis, and asthma, by using a nationwide data base. METHODS: A cohort of 155,311 patients newly diagnosed with atopic dermatitis, allergic rhinitis, or asthma in 2002-2011 was obtained from the Taiwan National Health Insurance Research Database...
September 1, 2017: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/28814273/add-on-neurological-benefits-of-antiviral-therapy-in-hcv-patients-with-chronic-kidney-disease-a-nationwide-cohort-study
#5
Ming-Shyan Lin, Tien-Hsing Chen, Wey-Yil Lin, Chi-Hung Liu, Yung-Yu Hsieh, Wen-Nan Chiu, Chih-Hsiang Chang, Mei-Yen Chen, Chang-Min Chung, Yu-Sheng Lin
BACKGROUND: Hepatitis C virus (HCV)-infected patients with chronic kidney disease (CKD) have rarely been studied because they rarely accept interferon-based therapy (IBT) and have been difficult to follow up. We investigated long-term outcomes of IBT on the population. METHODS: This population-based cohort study used the Taiwan National Health Insurance Research Database as its data source. HCV patients diagnosed with CKD between Jan. 1, 2003, and Dec. 31, 2013, were selected...
August 16, 2017: BMC Gastroenterology
https://www.readbyqxmd.com/read/28813508/increased-risk-of-tinnitus-in-patients-with-chronic-kidney-disease-a-nationwide-population-based-cohort-study
#6
Cheng-Ping Shih, Hung-Che Lin, Chi-Hsiang Chung, Po-Jen Hsiao, Chih-Hung Wang, Jih-Chin Lee, Wu-Chien Chien
Tinnitus mostly results from central and peripheral auditory pathology. Chronic kidney disease (CKD) is a major risk factor for cerebrovascular disease. However, no studies have evaluated the association between tinnitus and CKD. The aim of this study is to investigate the risk of tinnitus in patients with CKD. This retrospective cohort study was conducted using Taiwan National Health Insurance Research Database from 2000 to 2010. We established a CKD group (n = 185,430) and a non-CKD comparison group (n = 556,290) to investigate the incidence of tinnitus...
2017: PloS One
https://www.readbyqxmd.com/read/28813433/diabetes-risks-and-outcomes-in-chronic-obstructive-pulmonary-disease-patients-two-nationwide-population-based-retrospective-cohort-studies
#7
Chao-Shun Lin, Chih-Chung Liu, Chun-Chieh Yeh, Yi-Cheng Chang, Chi-Li Chung, Hsin-Long Lane, Chun-Chuan Shih, Ta-Liang Chen, Chien-Chang Liao
OBJECTIVE: The relationship between chronic obstructive pulmonary disease (COPD) and diabetes remains incompletely understood. This study evaluated diabetes risk and post-diabetes outcomes in COPD patients with and without exacerbations. METHODS: We identified 4671 adults newly diagnosed with COPD exacerbations and 9342 adults newly diagnosed with COPD without exacerbations during 2000-2008 using Taiwan's National Health Insurance Research Database. A comparison cohort of 18684 adults without COPD, matched by age and sex, was randomly selected from the same dataset for the control group...
2017: PloS One
https://www.readbyqxmd.com/read/28807849/danshen-improves-survival-of-patients-with-colon-cancer-and-dihydroisotanshinone-i-inhibit-the-proliferation-of-colon-cancer-cells-via-apoptosis-and-skp2-signaling-pathway
#8
Yin-Yin Lin, I-Yun Lee, Wen-Shih Huang, Yu-Shin Lin, Feng-Che Kuan, Li-Hsin Shu, Yu-Ching Cheng, Yao-Hsu Yang, Ching-Yuan Wu
ETHNOPHARMACOLOGICAL RELEVANCE: Danshen (Salvia miltiorrhiza Bunge) is widely used in traditional Chinese medicine. However, it's definite clinical effect and mechanism on colon carcinoma is unclear. AIM OF THE STUDY: To test the hypothesis that the protective effect of danshen on colon cancer and discover the bioactive compounds through in vitro study. MATERIALS AND METHODS: We conducted a nationwide cohort study by using population-based data from the Taiwan National Health Insurance Research Database (NHIRD)...
August 11, 2017: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/28806741/risk-of-cancer-in-patients-with-genital-warts-a-nationwide-population-based-cohort-study-in-taiwan
#9
Ching-Yi Cho, Yu-Cheng Lo, Miao-Chiu Hung, Chou-Cheng Lai, Chun-Jen Chen, Keh-Gong Wu
BACKGROUND: Condyloma acuminata currently affects around 1% of sexually active adults, and its incidence is increasing. The coexistence of genital warts (GW) and certain cancers and an association between human papillomavirus (HPV) and various malignancies have been reported. Therefore, we conducted this large national study to analyze the risk of malignancies among men and women with GW in Taiwan. METHODS AND FINDINGS: Between January 2000 and December 2013, approximately 3 million patients were reported to the National Health Insurance Research Database of Taiwan...
2017: PloS One
https://www.readbyqxmd.com/read/28803891/cholecystectomy-decreased-the-recurrent-cholangitis-after-clearance-of-bile-duct-stones-by-ercp-in-patients-with-gallstone-related-cholangitis
#10
Tseng-Shing Chen, Xi-Hsuan Lin, Yen-Ling Peng, Jiing-Chyuan Luo, Yung-Tai Chen, Ming-Chih Hou, Fa-Yauh Lee
BACKGROUND: This study assessed whether cholecystectomy can decrease recurrent cholangitis and all-cause mortality in patients who received endoscopic retrograde cholangiopancreatography (ERCP) with sphincterotomy and successful clearance of bile duct (BD) stones after gallstone-related cholangitis. METHODS: We analyzed data from the National Health Insurance research database of Taiwan. Patients who had gallstone-related cholangitis and underwent successful endoscopic clearance of BD stones were eligible for enrollment...
August 10, 2017: Journal of the Chinese Medical Association: JCMA
https://www.readbyqxmd.com/read/28801391/primary-sjogren-s-syndrome-and-the-risk-of-acute-pancreatitis-a-nationwide-cohort-study
#11
Chi-Ching Chang, Yu-Sheng Chang, Shu-Hung Wang, Shyr-Yi Lin, Yi-Hsuan Chen, Jin Hua Chen
OBJECTIVE: Studies on the risk of acute pancreatitis in patients with primary Sjogren's syndrome (pSS) are limited. We evaluated the effects of pSS on the risk of acute pancreatitis in a nationwide, population-based cohort in Taiwan. STUDY DESIGN: Population-based retrospective cohort study. SETTING: We studied the claims data of the >97% Taiwan population from 2002 to 2012. PARTICIPANTS: We identified 9468 patients with pSS by using the catastrophic illness registry of the National Health Insurance Database in Taiwan...
August 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28797986/increased-occurrence-of-brain-abscesses-in-cirrhotic-patients-a-population-based-3-year-follow-up-study
#12
Yen Chun Chen, Tsung Hsing Hung, Kuo Chih Tseng, Chih Wei Tseng, Yu Hsi Hsieh, Chih Chun Tsai, Chen Chi Tsai
BACKGROUND/AIMS: Cirrhotic patients are prone to various infectious diseases. However, it is still unknown if the occurrence of a brain abscess is associated with cirrhosis. The purpose of this study was to identify the relationship between the occurrence of a brain abscess and cirrhosis. MATERIALS AND METHODS: The National Health Insurance Database, which is derived from the Taiwan National Health Insurance program, was used to collect data from 40,878 patients with cirrhosis and from 40,896 randomly selected age- and sex-matched patients...
August 9, 2017: Turkish Journal of Gastroenterology: the Official Journal of Turkish Society of Gastroenterology
https://www.readbyqxmd.com/read/28793879/septic-arthritis-significantly-increased-the-long-term-mortality-in-geriatric-patients
#13
Chia-Jung Wu, Chien-Cheng Huang, Shih-Feng Weng, Ping-Jen Chen, Chien-Chin Hsu, Jhi-Joung Wang, How-Ran Guo, Hung-Jung Lin
BACKGROUND: The elderly are predisposed to septic arthritis (SA) because of the aging nature and increasing comorbidities. SA may in turn increase the long-term mortality in the geriatric patients; however, it remains unclear. We conducted this prospective nationwide population-based cohort study to clarify this issue. METHODS: Using Taiwan National Health Insurance Research Database (NHIRD), we identified 1667 geriatric participants (≥ 65 years) with SA and 16,670 geriatric participants without SA matched at a ratio of 1:10 by age, sex, and index date between 1999 and 2010...
August 9, 2017: BMC Geriatrics
https://www.readbyqxmd.com/read/28789832/association-of-preterm-birth-and-small-for-gestational-age-with-metabolic-outcomes-in%C3%A2-children-and-adolescents-a-population-based-cohort-study-from-taiwan
#14
Yu-Ting Huang, Hsiang-Yu Lin, Chung-Hsing Wang, Bai-Horng Su, Che-Chen Lin
BACKGROUND: Previous studies have identified preterm birth and/or small for gestational age (SGA) as risk factors for features of the metabolic syndrome, including high blood pressure, insulin sensitivity and atherosclerosis, occurring later in life, with controversial results. We conducted this population-based cohort study to investigate metabolic outcomes in those with former preterm birth and/or SGA status in Taiwan. METHODS: Data were obtained from Taiwan's universal National Health Insurance Research Database...
July 25, 2017: Pediatrics and Neonatology
https://www.readbyqxmd.com/read/28789796/the-bidirectional-relationship-between-anxiety-depression-and-lower-urinary-track-symptoms-a-nationwide-population-based-cohort-study
#15
Charles Lung-Cheng Huang, Ming-Ping Wu, Chung-Han Ho, Jhi-Joung Wang
BACKGROUND: Evidence has shown a positive correlation between lower urinary tract symptoms (LUTS) and anxiety/depression, but the direction and strength of the association are still unclear. We aimed to test the bidirectional association between LUTS and anxiety/depression using a longitudinal population database. METHODS: Using claims data obtained from the Taiwan National Health Insurance Research Database, 17,489 patients with LUTS and 34,978 non-LUTS matched controls (cohort 1); and 45,707 patients with anxiety, 19,306 patients with depression, 91,414 non-anxiety, and 38,720 non-depression matched controls (cohort 2) were enrolled between 1999 and 2008...
September 2017: Journal of Psychosomatic Research
https://www.readbyqxmd.com/read/28782528/the-use-of-benzodiazepine-receptor-agonists-and-the-risk-of-pneumonia-hospitalization-a-nationwide-population-based-nested-case-control-study
#16
Tien-Yu Chen, John W Winkelman, Wei-Chung Mao, Chia-Lin Liu, Chung-Yao Hsu, Chi-Shin Wu
BACKGROUND: The relationship between the use of benzodiazepine receptor agonists (BZRAs) and the risk of pneumonia hospitalization remains inconclusive. This study aimed to explore the association between BZRA use and pneumonia hospitalization in a general population. METHODS: This population-based, nested case-control study used Taiwan's National Health Insurance Research Database between 2002 and 2012. We only included new users who did not have any BZRA prescriptions on record in the preceding two years and identified 12,002 subjects with pneumonia hospitalization (ICD-9 codes: 480-486) and 12,002 disease risk score matched controls...
August 4, 2017: Chest
https://www.readbyqxmd.com/read/28781299/an-analysis-of-emergency-department-visits-and-the-survival-rate-for-colorectal-cancer-patients-a-nationwide-population-based-study
#17
Pei-Ling Tang, Hong-Tai Chang, Chin-Chang Cheng, Hung-Chih Chen, Shyh-Ming Kuo, Kuan-Yin Hsiao, Kuo-Chen Chang
Objective We examined the general characteristics, survival rate, and most common reasons for visiting the emergency department (ED) among colorectal cancer patients in Taiwan. We performed a population-based retrospective study and used data sourced from the National Health Insurance Research Database (NHIRD). Methods The colorectal cancer patient population, their diagnosis, and their medical management at the ED were identified using the Longitudinal Health Insurance Database 2000 (HV) codes and International Classification of Diseases, Ninth Revision, Clinical Modification system...
August 1, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28778079/nationwide-cohort-study-on-the-epidemiology-and-survival-outcomes-of-thyroid-cancer
#18
Fu-Chao Liu, Huan-Tang Lin, Shu-Fu Lin, Chang-Fu Kuo, Ting-Ting Chung, Huang-Ping Yu
In the past three decades, the thyroid cancer incidence has surged globally. Herein, the Taiwan National Health Insurance database was used to identify thyroid cancer patients and to estimate the prevalence and incidence of thyroid cancer during 1997-2012. The Taiwan Cancer Registry and the National Death Registry databases were crosslinked to obtain information on the histological subtypes and survival rates. Joinpoint regression analysis was used for estimating the average annual percentage changes (APCs) in prevalence, incidence, and survival...
July 22, 2017: Oncotarget
https://www.readbyqxmd.com/read/28771753/sleep-apnea-and-risk-of-vertigo-a-nationwide-population-based-cohort-study
#19
Ming-Shao Tsai, Li-Ang Lee, Yao-Te Tsai, Yao-Hsu Yang, Chia-Yen Liu, Meng-Hung Lin, Cheng-Ming Hsu, Chin-Kuo Chen, Hsueh-Yu Li
OBJECTIVE: To investigate the risk of vertigo in patients with sleep apnea. STUDY DESIGN: Retrospective cohort study. METHODS: This study used data from the National Health Insurance Research Database of Taiwan, a population-based database. A total of 5,025 patients who were newly diagnosed with sleep apnea between January 1, 1997, and December 31, 2012, were identified from the Longitudinal Health Insurance Database 2000, a nationally representative database of 1 million randomly selected patients...
August 3, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28771692/predialysis-chronic-kidney-disease-correlates-with-increased-risk-of-pyogenic-liver-abscess-a-population-based-cohort-study
#20
Shih-Wei Lai, Cheng-Li Lin, Kuan-Fu Liao
BACKGROUND/OBJECTIVE: The incidence of pyogenic liver abscess in Taiwan appears to be much higher than that in western countries. However, little is known about the incidence of pyogenic liver abscess among patients with predialysis chronic kidney disease. The objective of this study was to assess the association between predialysis chronic kidney disease and the risk of pyogenic liver abscess in Taiwan. METHODS: This population-based, retrospective, cohort study was conducted to analyze the database of the Taiwan National Health Insurance Program...
August 3, 2017: European Journal of Clinical Investigation
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