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https://www.readbyqxmd.com/read/29239678/the-effect-of-antibiotic-prophylaxis-for-acute-pelvic-inflammatory-disease-after-hysterosalpingography-a-retrospective-cohort-study
#1
Hao-Ming Li, Fung-Chang Sung, Shang-Chieh Li, Ying-Kai Huang, Yu Chang, Chi-Chang Chang, S Joseph Huang, Cheng-Li Lin, Chia-Hung Kao
AIMS: The concern about acute pelvic inflammatory disease (PID) after hysterosalpingography (HSG) has been raised since 1980. However, the effectiveness of prophylactic antibiotics remains unclear. This study investigated the effect of antibiotic prophylaxis in women undergoing HSG. METHODS: Women undergoing HSG between 2000 and 2012 were screened from Taiwan National Health Insurance Research Database for eligibility. The prophylactic cohort included patients using any antibiotics of 1st-generation cephalosporins, doxycycline, clindamycin, and metronidazole, within seven days before HSG (Nā€‰=ā€‰3257)...
December 14, 2017: Current Medical Research and Opinion
https://www.readbyqxmd.com/read/29238221/selective-serotonin-reuptake-inhibitors-and-the-risk-of-hepatocellular-carcinoma-in-hepatitis-b-virus-infected-patients
#2
Chia-Ming Chang, Ming-Shun Hsieh, Tsung-Chieh Yang, Vivian Chia-Rong Hsieh, Jen-Huai Chiang, Hsien-Hao Huang, Chorng-Kuang How, Sung-Yuan Hu, David Hung-Tsang Yen
Background: This study aimed to investigate the association between the use of selective serotonin reuptake inhibitors (SSRIs) and the risk of hepatocellular carcinoma (HCC) in patients with chronic hepatitis B virus (HBV) infection. Methods: We conducted a population-based cohort study by using claims data from the Taiwan National Health Insurance Research Database (NHIRD). The study cohort comprised 1380 newly diagnosed HBV-infected patients with SSRI use who were frequency matched by age, sex, liver cirrhosis, and index year with HBV-infected patients without SSRI use in the comparison cohort...
2017: Cancer Management and Research
https://www.readbyqxmd.com/read/29230549/a-nationwide-survey-of-incidence-rates-and-risk-factors-of-inguinal-hernia-in-preterm-children
#3
Yu-Wei Fu, Mei-Lien Pan, Yao-Jen Hsu, Tai-Wai Chin
PURPOSE: Clinical observations showed a higher incidence rate of inguinal hernia (IH) in preterm infants. In this study, we calculated the incidence rate of preterm IH from the National Health Insurance Research Database (NHIRD) of Taiwan. METHODS: From NHIRD, 92,308 subjects born in the year of 1997-2005 were randomly selected as the study cohort. The medical claims of these subjects from birth to 6th year of age were analyzed. Preterm births were defined using ICD code 765...
December 11, 2017: Pediatric Surgery International
https://www.readbyqxmd.com/read/29229082/asthma-is-associated-with-endometriosis-a-retrospective-population-based-cohort-study
#4
Yi-Hao Peng, Shan-Yu Su, Wei-Chih Liao, Chien-Wen Huang, Chung Y Hsu, Hsuan-Ju Chen, Trong-Neng Wu, Wen-Chao Ho, Chin-Ching Wu
BACKGROUND: Evidence regarding the association between asthma and endometriosis is limited and inconsistent. The goal of the study was to investigate whether women diagnosed as having asthma were at a greater risk of endometriosis than age-matched unaffected women. METHODS: We conducted a nationwide population-based retrospective study by using data retrieved from the Taiwan National Health Insurance Research Database during the period of 2000-2005 with follow-up through 2013...
November 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/29228568/sitagliptin-and-oral-cancer-risk-in-type-2-diabetes-patients
#5
Chin-Hsiao Tseng
The reimbursement database of the Taiwan's National Health Insurance was used to evaluate oral cancer risk after sitagliptin use. Patients newly diagnosed of type 2 diabetes during 1999-2008 were recruited. A 1:1 propensity score matched-pair sample of 39195 ever users and 39195 never users were followed up until December 31, 2011. Cox regression incorporated with the inverse probability of treatment weighting using propensity score was used to estimate hazard ratios. Results showed that the overall hazard ratio was not statistically significant (0...
November 14, 2017: Oncotarget
https://www.readbyqxmd.com/read/29227012/superior-anti-suicidal-effects-of-electroconvulsive-therapy-in-unipolar-disorder-and-bipolar-depression
#6
Chih-Sung Liang, Chi-Hsiang Chung, Pei-Shen Ho, Chia-Kuang Tsai, Wu-Chien Chien
OBJECTIVES: Electroconvulsive therapy (ECT) has long been believed to reduce suicidal tendencies in patients with affective disorders; however, ECT recipients, who constitute the most severely ill and suicidal patients, are not eligible to participate in head-to-head randomized controlled trials. Large-scale studies are required to investigate the anti-suicidal effects of ECT vs psychopharmacotherapy. METHODS: A nationwide retrospective cohort study design was used...
December 11, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/29224375/autoimmune-rheumatic-diseases-and-the-risk-of-parkinson-disease-a-nationwide-population-based-cohort-study-in-taiwan
#7
Chi-Ching Chang, Tzu-Min Lin, Yu-Sheng Chang, Wei-Sheng Chen, Jau-Jiuan Sheu, Yi-Hsuan Chen, Jin-Hua Chen
BACKGROUNDS: In autoimmune rheumatic diseases (ARDs), the levels of inflammatory mediators are increased and microglia may be activated, resulting in an inflammatory state and the degeneration of dopaminergic neurons. We investigated the association between ARDs and Parkinson disease (PD). METHODS: We identified ARD patients through the Taiwan National Health Insurance Research Database from 2001 to 2012. From the general population, we randomly selected a comparison cohort that was frequency-matched by age (in 5-year increments), sex, and index year...
December 11, 2017: Annals of Medicine
https://www.readbyqxmd.com/read/29218625/diuretic-or-beta-blocker-for-hypertensive-patients-already-receiving-acei-arb-and-calcium-channel-blocker
#8
Min-Shan Tsai, Chao-Hsiun Tang, Chia-Ying Lin, Po-Ya Chuang, Nai-Chuan Chen, Chien-Hua Huang, Wei-Tien Chang, Tzung-Dau Wang, Ping-Hsun Yu, Wen-Jone Chen
BACKGROUND: In patients already receiving combination of angiotensin-converting enzyme inhibitor (ACEI)/angiotensin receptor blocker (ARB) and calcium channel blocker (CCB), whether the choice of additional diuretic or beta-blocker affects the cardiovascular and cerebrovascular outcomes remains unclear. METHODS: A total of 13,551 patients who were concurrently receiving three anti-hypertensive agents of different classes through outpatient clinics during 2004-2006 were identified from the National Health Insurance Research Database of Taiwan...
December 8, 2017: Cardiovascular Drugs and Therapy
https://www.readbyqxmd.com/read/29216345/effect-of-influenza-vaccination-against-postoperative-pneumonia-and-mortality-for-geriatric-patients-receiving-major-surgery-a-nationwide-matched-study
#9
Wan-Chi Liu, Chao-Shun Lin, Chun-Chieh Yeh, Hsin-Yun Wu, Yuarn-Jang Lee, Chi-Li Chung, Yih-Giun Cherng, Ta-Liang Chen, Chien-Chang Liao
Background: Limited information is available on the association between a influenza vaccination and postoperative outcomes. Methods: Using Taiwan's National Health Insurance Research Database reimbursement claims data from 2008 to 2013, we conducted a matched cohort study of 16,903 patients over age 66 who received influenza vaccinations and later underwent major surgery. Using propensity score matching procedure adjusted for socio-demographics, medical conditions, types of surgery and anesthesia, 16,903 controls who were not vaccinated were selected...
December 5, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/29216286/migraine-and-risk-of-narcolepsy-in-children-a-nationwide-longitudinal-study
#10
Chun-Pai Yang, Meng-Lun Hsieh, Jen-Huai Chiang, Hsing-Yi Chang, Vivian Chia-Rong Hsieh
BACKGROUND: The association between migraine and narcolepsy remains controversial. We aim to investigate whether migraine is associated with an increased risk of developing narcolepsy in children. METHODS: In this longitudinal study, nationwide medical-claims data of pediatric patients (0-17y) with migraine are identified using the National Health Insurance Research Database (NHIRD) between 1997 and 2010 in Taiwan. Two cohorts are selected: migraine cases (n = 8,923) and propensity score-matched non-migraine controls (n = 35,692)...
2017: PloS One
https://www.readbyqxmd.com/read/29213242/case-control-study-examining-the-association-between-selective-serotonin-reuptake-inhibitors-use-and-hepatocellular-carcinoma
#11
Shih-Wei Lai, Kuan-Fu Liao, Cheng-Li Lin, Hsien-Feng Lin
Objectives: The purpose of the study was to assess the relationship between selective serotonin reuptake inhibitors use and hepatocellular carcinoma in Taiwan. Methods: Using the database of the Taiwan National Health Insurance Program, we conducted a case-control study to identify 4901 subjects aged 20 years and more with newly diagnosed hepatocellular carcinoma in 2000-2013 as the cases. We randomly selected 19604 subjects aged 20 years and more without hepatocellular carcinoma as the controls. Both cases and controls were matched with sex and age...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29213240/dipeptidyl-peptidase-4-inhibitors-use-and-relative-risk-of-ischemic-cerebrovascular-disease-in-type-2-diabetic-patients-in-a-case-control-study
#12
Shih-Wei Lai, Kuan-Fu Liao, Cheng-Li Lin, Hsien-Feng Lin
Background and Objectives: Limited research focuses on the risk of ischemic cerebrovascular disease associated with use of dipeptidyl peptidase-4 inhibitors (DPP-4 inhibitors) in patients with type 2 diabetes mellitus in Taiwan. This study aimed to investigate the association between DPP-4 inhibitors use and the first episode of ischemic cerebrovascular disease. Methods: We designed a case-control study using the database of the Taiwan National Health Insurance Program. There were 1999 type 2 diabetic subjects aged 20-84 years with the first episode of ischemic cerebrovascular disease from 2000 to 2013 as the cases, and 7996 sex- and age-matched, randomly selected type 2 diabetic subjects aged 20-84 years without any type of cerebrovascular diseases as the matched controls...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29210149/retinal-vascular-complications-associated-with-interferon-ribavirin-therapy-for-chronic-hepatitis-c-a-population-based-study
#13
Chien-Hsiung Lai, Yao-Hsu Yang, Pau-Chung Chen, Ying-Chi King, Chia-Yen Liu
PURPOSE: To investigate the incidence of retinal vascular complications and risk factors in patients with chronic hepatitis C receiving interferon-ribavirin therapy in Taiwan. METHODS: By using the Taiwan National Health Insurance Research Database, we compared the incidence of retinal vascular complications between patients receiving and not receiving interferon-ribavirin treatment. The exposure and nonexposure groups were randomly 1:1 frequency-matched according to age, sex, income, urbanization level, hypertension, and diabetes...
December 6, 2017: Pharmacoepidemiology and Drug Safety
https://www.readbyqxmd.com/read/29209380/health-care-utilization-and-expenditures-of-patients-with-diabetes-comorbid-with-depression-disorder-a-national-population-based-cohort-study
#14
Chun-Jen Huang, Hui-Min Hsieh, Herng-Chia Chiu, Peng-Wei Wang, Mei-Hsuan Lee, Chih-Yi Li, Ching-Hua Lin
Objective: The study investigated to compare health care utilization and expenditures between diabetic patients with and without depression in Taiwan. Methods: Health care utilization and expenditure among diabetic patients with and without depression disorder during 2000 and 2004 were examined using Taiwan's population-based National Health Insurance claims database. Health care utilization included outpatient visits and the use of inpatient services, and health expenditures were outpatient, inpatient, and total medical expenditures...
November 2017: Psychiatry Investigation
https://www.readbyqxmd.com/read/29207978/potential-therapeutic-effects-of-n-butylidenephthalide-from-radix-angelica-sinensis-danggui-in-human-bladder-cancer-cells
#15
Sheng-Chun Chiu, Tsung-Lang Chiu, Sung-Ying Huang, Shu-Fang Chang, Shee-Ping Chen, Cheng-Yoong Pang, Teng-Fu Hsieh
BACKGROUND: N-butylidenephthalide (BP) isolated from Radix Angelica Sinensis (Danggui) exhibits anti-tumorigenic effect in various cancer cells both in vivo and in vitro. The effect of BP in bladder cancer treatment is still unclear and worth for further investigate. METHODS: Changes of patients with bladder cancer after Angelica Sinensis exposure were evaluated by analysis of Taiwan's National Health Insurance Research Database (NHIRD) database. The anti-proliferative effect of BP on human bladder cancer cells was investigated and their cell cycle profiles after BP treatment were determined by flow cytometry...
December 6, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29207614/danshen-improves-survival-of-patients-with-advanced-lung-cancer-and-targeting-the-relationship-between-macrophages-and-lung-cancer-cells
#16
Ching-Yuan Wu, Jong-Yuh Cherng, Yao-Hsu Yang, Chun-Liang Lin, Feng-Che Kuan, Yin-Yin Lin, Yu-Shih Lin, Li-Hsin Shu, Yu-Ching Cheng, Hung Te Liu, Ming-Chu Lu, Jthau Lung, Pau-Chung Chen, Hui Kuan Lin, Kuan-Der Lee, Ying-Huang Tsai
In traditional Chinese medicine, Salvia miltiorrhiza Bunge (danshen) is widely used in the treatment of numerous cancers. However, its clinical effort and mechanism in the treatment of advanced lung cancer are unclear. In our study, the in vivo protective effort of danshen in patients with advanced lung cancer were validated using data from the National Health Insurance Research Database in Taiwan. We observed in vitro that dihydroisotanshinone I (DT), a bioactive compound in danshen, exerts anticancer effects through many pathways...
October 31, 2017: Oncotarget
https://www.readbyqxmd.com/read/29206719/trends-in-urodynamic-procedures-surgical-procedures-and-overall-health-resource-utilization-in-the-adult-taiwanese-population-with-urinary-incontinence-a-secondary-data-analysis
#17
Lan-Fang Hsu, Ling-Yin Chang, Yuan-Mei Liao, Shauh-Der Yeh, Pei-Shan Tsai
BACKGROUND: The prevalence and incidence of the main risk factors for urinary incontinence (UI) have both increased over time. In addition, official statistics indicate that Taiwan is on course to evolve from an aging society into an aged society within the next decade. However, most of the studies in the literature that address the natural history of UI target Western and other non-Asian populations. Taiwan lacks knowledge of the natural history of UI. PURPOSE: The aims of this research were to study the trends in the use of urodynamic and surgical procedures for various subtypes of UI and to investigate the relationship between UI and healthcare resource utilization...
December 4, 2017: Journal of Nursing Research: JNR
https://www.readbyqxmd.com/read/29194494/impact-of-bundled-payments-on-hip-fracture-outcomes-a-nationwide-population-based-study
#18
Yu-Chi Tung, Hsien-Yen Chang, Guann-Ming Chang
Objective: Establishing one price for all bundled services for a particular illness, which has become the key to healthcare reform efforts, is designed to encourage health professionals to coordinate their care for patients. Limited information is available, however, concerning whether bundled payments are associated with changes in patient outcomes. Nationwide longitudinal population-based data were used to examine the effect of bundled payments on hip fracture outcomes. Design: An interrupted time series design with a comparison group...
November 29, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29194450/risk-of-infertility-following-pelvic-angiographic-embolization-in-female-patients-with-pelvic-fractures-a-nationwide-population-based-cohort-study-in-taiwan
#19
Sheng-Der Hsu, Shih-Yu Lee, Kuen-Tze Lin, Chun-Shu Lin, Wu-Chien Chien, Cheng-Jueng Chen, Chi-Hsiang Chung, Wei-Kuo Chang
Pelvic angiographic embolization is an effective procedure to provide haemostasis in patients with pelvic fractures. However, management with repeated follow-up radiographs may result in infertility. The study aimed to evaluate the risk of infertility following pelvic fracture treated with pelvic angiographic embolization in female patients. We used data from the National Health Insurance Research Database (NHIRD) provided by the Bureau of National Health Insurance of the Department of Health in Taiwan from the period of 1997-2010...
2017: PloS One
https://www.readbyqxmd.com/read/29193835/incident-spine-surgery-in-patients-with-ankylosing-spondylitis-a-secondary-cohort-analysis-of-a-nationwide-population-based-health-claims-database
#20
Ming-Chi Lu, Malcolm Koo, Ning-Sheng Lai
OBJECTIVE: To evaluate the risk for the need of spine surgery, including cervical and lumbar spine surgeries in patients with ankylosing spondylitis (AS) compared with those without the disease. METHODS: A secondary data analysis was conducted using population-based claims data from the Taiwan's National Health Insurance Research Database. Adult patients with newly diagnosed AS between January 2000 and December 2012, were identified based on the International Classification of Diseases, 9th Revision, Clinical Modification code 720...
November 28, 2017: Arthritis Care & Research
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