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https://www.readbyqxmd.com/read/28915812/the-economic-burden-of-advanced-gastric-cancer-in-taiwan
#1
Jihyung Hong, Yiling Tsai, Diego Novick, Frank Chi-Huang Hsiao, Rebecca Cheng, Jen-Shi Chen
BACKGROUND: Gastric cancer is one of the leading causes of cancer-related deaths in both sexes worldwide, especially in Eastern Asia. This study aimed to estimate the economic burden of advanced gastric cancer (AGC) in Taiwan. METHODS: The costs of AGC in 2013 were estimated using resource use data from a chart review study (n = 122 with AGC) and national statistics. Annual per-patient costs, where patients' follow-up periods were adjusted for, were estimated with 82 patients who had complete resource use data...
September 16, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/28914680/outcomes-in-patients-treated-with-a-novel-simple-method-for-hemostasis-of-dermal-avulsion-injuries
#2
Sean Taylor Dowling, Brian Wai Lin
OBJECTIVE: A recently described technique proposes a simple method to achieve permanent hemostasis of distal fingertip dermal avulsion injuries. It is simple to learn and easy to perform with readily available materials found in most emergency departments. However, long-term outcomes for patients treated with this technique have not yet been evaluated. A primary objective of the current article is to provide safety data for the technique using an off-label product indication. SETTING: Emergency department of Kaiser Permanente Medical Center, San Francisco, California...
October 2017: Advances in Skin & Wound Care
https://www.readbyqxmd.com/read/28914185/power-potential-and-pitfalls-in-global-health-academic-partnerships-review-and-reflections-on-an-approach-in-nepal
#3
David Citrin, Stephen Mehanni, Bibhav Acharya, Lena Wong, Isha Nirola, Rekha Sherchan, Bikash Gauchan, Khem Bahadur Karki, Dipendra Raman Singh, Sriram Shamasunder, Phuoc Le, Dan Schwarz, Ryan Schwarz, Binod Dangal, Santosh Kumar Dhungana, Sheela Maru, Ramesh Mahar, Poshan Thapa, Anant Raut, Mukesh Adhikari, Indira Basnett, Shankar Prasad Kaluanee, Grace Deukmedjian, Scott Halliday, Duncan Maru
BACKGROUND: Global health academic partnerships are centered around a core tension: they often mirror or reproduce the very cross-national inequities they seek to alleviate. On the one hand, they risk worsening power dynamics that perpetuate health disparities; on the other, they form an essential response to the need for healthcare resources to reach marginalized populations across the globe. OBJECTIVES: This study characterizes the broader landscape of global health academic partnerships, including challenges to developing ethical, equitable, and sustainable models...
2017: Global Health Action
https://www.readbyqxmd.com/read/28914126/patient-navigators-effectively-support-hiv-infected-individuals-returning-to-the-community-from-jail-settings
#4
Janet J Myers, Kimberly A Koester, Mi-Suk Kang Dufour, Alison O Jordan, Jacqueline Cruzado-Quinone, Alissa Riker
Purpose Patient navigation is an evidence-based approach for enhancing medical and support service co-ordination and ensuring linkage to medical care for people living with HIV released from jail. The paper aims to discuss this issue. Design/methodology/approach This brief describes the benefits of patient navigation and issues to consider when implementing a navigator program. The authors use process data to describe the type and amount of navigation services delivered as part of a randomized study, the "The San Francisco Navigator Project...
September 11, 2017: International Journal of Prisoner Health
https://www.readbyqxmd.com/read/28913829/a-retrospective-examination-of-child-protection-involvement-among-young-adults-accessing-homelessness-services
#5
Emily Putnam-Hornstein, Bridgette Lery, Jonathan Hoonhout, Susanna Curry
Childhood maltreatment is associated with a variety of young adult adversities including homelessness. This study used linked administrative records to develop a population-level, epidemiological characterization of the child protection histories of young adults accessing homelessness services. The records of all 17- to 24-year-olds receiving homeless services between 2011 and 2014 in San Francisco County, California (n = 2241) were probabilistically linked to statewide child protective service (CPS) records...
September 15, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28905358/prognosis-communication-in-late-life-disability-a-mixed-methods-study
#6
Theresa W Wong, Sean Lang-Brown, Rafael D Romo, Alvin Au-Yeung, Sei J Lee, Patricia J Moran, Jason Karlawish, Rebecca Sudore, Josephine Clayton, Alexander K Smith
IMPORTANCE: Long-term prognosis informs clinical and personal decisions for older adults with late-life disability. However, many clinicians worry that telling patients their prognosis may cause harm. OBJECTIVE: To explore the safety of and reactions to prognosis communication in late-life disability. DESIGN: Participants estimated their own life expectancy and were then presented their calculated life expectancy using a validated prognostic index...
September 14, 2017: Journal of the American Geriatrics Society
https://www.readbyqxmd.com/read/28902338/confluent-endpoint-subthreshold-argon-laser-for-serous-macular-detachment-in-tilted-disc-syndrome-refractory-to-anti-vegf
#7
Maria Fernanda Abalem, Pedro Carlos Carricondo, Helen Nazareth Veloso Dos Santos, Rafael Garcia, Cynthia X Qian, John Helal, Eduardo Cunha de Souza, Walter Yukihiko Takahashi
A 70-year-old woman presented with 20/200 visual acuity in the right eye. Multimodal imaging revealed tilted disc syndrome (TDS) with macular serous detachment (MSD) and pigmentary changes at the temporal margin of the optic disc. Subretinal fluid persisted after three monthly intravitreal bevacizumab (Avastin; Genentech, South San Francisco, CA) injections and threshold focal laser photocoagulation. Subsequently, confluent subthreshold argon laser was applied over the entire area of retinal pigment epithelium (RPE) abnormalities, resulting in the resolution of subretinal fluid without recurrence through 3 years of follow-up...
September 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28902334/multicenter-randomized-clinical-trial-to-assess-the-effectiveness-of-intravitreal-injections-of-bevacizumab-triamcinolone-or-their-combination-in-the-treatment-of-diabetic-macular-edema
#8
Hermelino O Neto, Caio V Regatieri, Mário J Nobrega, Cristina Muccioli, Antonio M Casella, Rafael E Andrade, Mauricio Maia, Vinicius Kniggendorf, Magno Ferreira, André C Branco, Rubens Belfort
BACKGROUND AND OBJECTIVE: To evaluate the efficacy of combined bevacizumab-triamcinolone intravitreal injection in the treatment of diabetic macular edema (DME) compared to monotherapy. PATIENTS AND METHODS: At eight clinical sites, 111 patients with DME were randomly assigned to receive an intravitreal injection of bevacizumab (Avastin; Genentech, South San Francisco, CA), triamcinolone (Ophthalmos Pharmaceutical Industry, São Paulo-SP, Brazil), or their combination...
September 1, 2017: Ophthalmic Surgery, Lasers & Imaging Retina
https://www.readbyqxmd.com/read/28899629/what-is-confidence-and-what-could-affect-it-a-qualitative-study-of-mothers-who-are-hesitant-about-vaccines
#9
Judith A Mendel-Van Alstyne, Glen J Nowak, Ann L Aikin
BACKGROUND: Public confidence in immunization is critical to maintaining high vaccine-coverage rates needed to protect individuals and communities from vaccine-preventable diseases. Recent attention has been placed on factors influencing confidence in vaccination in the US and globally, but comprehensive understanding of what drives or hinders confidence in childhood vaccination is yet to be reached. As such, assessing parents' confidence in childhood vaccination and the ways in which educational materials affect confidence is needed...
September 9, 2017: Vaccine
https://www.readbyqxmd.com/read/28895918/trauma-affecting-asian-pacific-islanders-in-the-san-francisco-bay-area
#10
Pollie Bith-Melander, Nagia Chowdhury, Charulata Jindal, Jimmy T Efird
Trauma is a transgenerational process that overwhelms the community and the ability of family members to cope with life stressors. An anthropologist trained in ethnographic methods observed three focus groups from a non-profit agency providing trauma and mental health services to Asian Americans living in the San Francisco Bay Area of United States. Supplemental information also was collected from staff interviews and notes. Many of the clients were immigrants, refugees, or adult children of these groups. This report consisted of authentic observations and rich qualitative information to characterize the impact of trauma on refugees and immigrants...
September 12, 2017: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/28894793/infiltrative-hepatocellular-carcinoma-with-portal-vein-tumor-thrombosis-treated-with-a-single-high-dose-y90-radioembolization-and-subsequent-liver-transplantation-without-a-recurrence
#11
Meaghan S Dendy, Juan C Camacho, Johannes M Ludwig, Alyssa M Krasinskas, Stuart J Knechtle, Hyun S Kim
BACKGROUND: Infiltrative hepatocellular carcinoma with macrovascular invasion is a relatively rare presentation and usually fatal disease. METHODS: Both patients exceeded Milan and University of California-San Francisco (UCSF) criteria, and per Barcelona Clinic Liver Cancer group guidelines, they were enrolled in a prospective open-label radioembolization phase II trial that gave them optimized lobar doses of Yttrium-90 as solely the first-line therapy without concomitant or additional pharmacological or locoregional therapies...
September 2017: Transplantation Direct
https://www.readbyqxmd.com/read/28893341/validation-of-a-survey-to-examine-drinking-water-access-practices-and-policies-in-schools
#12
Amelie A Hecht, Jacob M Grumbach, Karla E Hampton, Kenneth Hecht, Ellen Braff-Guajardo, Claire D Brindis, Charles E McCulloch, Anisha I Patel
OBJECTIVE: Ensuring ready access to free drinking-water in schools is an important strategy for prevention of obesity and dental caries, and for improving student learning. Yet to date, there are no validated instruments to examine water access in schools. The present study aimed to develop and validate a survey of school administrators to examine school access to beverages, including water and sports drinks, and school and district-level water-related policies and practices. DESIGN: Survey validity was measured by comparing results of telephone surveys of school administrators with on-site observations of beverage access and reviews of school policy documents for any references to beverages...
September 12, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28892301/deep-nirs-amplicon-sequencing-of-san-francisco-bay-sediments-enables-prediction-of-geography-and-environmental-conditions-from-denitrifying-community-composition
#13
Jessica A Lee, Christopher A Francis
Denitrification is a dominant nitrogen loss process in the sediments of San Francisco Bay. In this study, we sought to understand the ecology of denitrifying bacteria by using next-generation sequencing (NGS) to survey the diversity of a denitrification functional gene, nirS (encoding cytchrome-cd1 nitrite reductase), along the salinity gradient of San Francisco Bay over the course of a year. We compared our dataset to a library of nirS sequences obtained previously from the same samples by standard PCR cloning and Sanger sequencing, and showed that both methods similarly demonstrated geography, salinity, and, to a lesser extent, nitrogen, to be strong determinants of community composition...
September 11, 2017: Environmental Microbiology
https://www.readbyqxmd.com/read/28891344/when-the-cure-is-the-risk-understanding-how-substance-use-affects-hiv-and-hcv-in-a-layered-risk-environment-in-san-juan-puerto-rico
#14
Diana Hernández, Pedro C Castellón, Yohansa Fernández, Francisco A Torres-Cardona, Carrigan Parish, Danielle Gorshein, Jose Vargas Vidot, Sandra Miranda de Leon, Allan Rodriguez, Jorge Santana Bagur, Daniel J Feaster, Bruce R Schackman, Lisa R Metsch
BACKGROUND: Substance use, particularly injection drug use, continues to fuel the HIV/HCV (hepatitis C virus) epidemics in San Juan, Puerto Rico (PR). AIM: This article examines individual and sociostructural factors that affect HIV/HCV risk among people who use drugs (PWUD) living with or at risk for HIV/HCV in San Juan, PR. Findings were used to inform a community-level intervention to enhance HIV care access and retention for this population. METHOD: A rapid ethnographic assessment in collaboration with a community-based organization was conducted...
September 1, 2017: Health Education & Behavior: the Official Publication of the Society for Public Health Education
https://www.readbyqxmd.com/read/28891237/the-incidence-and-prevalence-of-systemic-lupus-erythematosus-in-san-francisco-county-california-the-california-lupus-surveillance-project
#15
Maria Dall'Era, Miriam G Cisternas, Kurt Snipes, Lisa J Herrinton, Caroline Gordon, Charles G Helmick
OBJECTIVE: Estimates of the incidence and prevalence of systemic lupus erythematosus (SLE) in the US have varied widely. The purpose of this study was to conduct the California Lupus Surveillance Project (CLSP) to determine credible estimates of SLE incidence and prevalence, with a special focus on Hispanics and Asians. METHODS: The CLSP, which is funded by the Centers for Disease Control and Prevention, is a population-based registry of individuals with SLE residing in San Francisco County, CA, from January 1, 2007 through December 31, 2009...
September 10, 2017: Arthritis & Rheumatology
https://www.readbyqxmd.com/read/28888919/patterns-of-perinatal-depression-and-stress-in-late-adolescent-and-young-adult-mothers
#16
Rosamar Torres, Deepika Goyal, Amanda C Burke-Aaronson, Caryl L Gay, Kathryn A Lee
OBJECTIVE: To compare symptoms of depression, maternal adjustment, and perceived stress in late adolescent and young adult mothers and to examine the patterns of these symptoms during the first 3 months after birth. DESIGN: Secondary analysis of extant longitudinal data. SETTING: San Francisco Bay Area, with participants in their home environments. PARTICIPANTS: Ethnically diverse women expecting their first infants recruited during the third trimester from childbirth education classes and antenatal clinics...
September 6, 2017: Journal of Obstetric, Gynecologic, and Neonatal Nursing: JOGNN
https://www.readbyqxmd.com/read/28888158/predicting-motorcycle-crash-injury-severity-using-weather-data-and-alternative-bayesian-multivariate-crash-frequency-models
#17
Wen Cheng, Gurdiljot Singh Gill, Taha Sakrani, Mohan Dasu, Jiao Zhou
Motorcycle crashes constitute a very high proportion of the overall motor vehicle fatalities in the United States, and many studies have examined the influential factors under various conditions. However, research on the impact of weather conditions on the motorcycle crash severity is not well documented. In this study, we examined the impact of weather conditions on motorcycle crash injuries at four different severity levels using San Francisco motorcycle crash injury data. Five models were developed using Full Bayesian formulation accounting for different correlations commonly seen in crash data and then compared for fitness and performance...
September 6, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/28887118/trabecular-meshwork-height-in-primary-open-angle-glaucoma-versus-primary-angle-closure-glaucoma
#18
Marisse Masis, Rebecca Chen, Travis Porco, Shan C Lin
PURPOSE: To determine if trabecular meshwork (TM) height differs between primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG) eyes. Design; Prospective, cross-sectional clinical study. METHODS: Adult patients were consecutively recruited from glaucoma clinics at the University of California, San Francisco, from January 2012 to July 2015. Images were obtained from spectral-domain optical coherence tomography (Cirrus OCT, CarlZeiss Meditec, Inc...
September 5, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28878380/an-in-silico-approach-to-predict-and-exploit-synthetic-lethality-in-cancer-metabolism
#19
Iñigo Apaolaza, Edurne San José-Eneriz, Luis Tobalina, Estíbaliz Miranda, Leire Garate, Xabier Agirre, Felipe Prósper, Francisco J Planes
Synthetic lethality is a promising concept in cancer research, potentially opening new possibilities for the development of more effective and selective treatments. Here, we present a computational method to predict and exploit synthetic lethality in cancer metabolism. Our approach relies on the concept of genetic minimal cut sets and gene expression data, demonstrating a superior performance to previous approaches predicting metabolic vulnerabilities in cancer. Our genetic minimal cut set computational framework is applied to evaluate the lethality of ribonucleotide reductase catalytic subunit M1 (RRM1) inhibition in multiple myeloma...
September 6, 2017: Nature Communications
https://www.readbyqxmd.com/read/28874160/preterm-birth-the-role-of-knowledge-transfer-and-exchange
#20
Hacsi Horvath, Claire D Brindis, E Michael Reyes, Gavin Yamey, Linda Franck
BACKGROUND: Preterm birth (PTB) is the leading cause of death in children under age five. Healthcare policy and other decision-making relevant to PTB may rely on obsolete, incomplete or inapplicable research evidence, leading to worsened outcomes. Appropriate knowledge transfer and exchange (KTE) strategies are an important component of efforts to reduce the global PTB burden. We sought to develop a 'landscape' analysis of KTE strategies currently used in PTB and related contexts, and to make recommendations for optimising programmatic implementation and for future research...
September 6, 2017: Health Research Policy and Systems
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