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https://www.readbyqxmd.com/read/29053511/decreasing-the-incidence-of-tuohy-borst-clamp-connector-disconnections-from-perineural-catheters-a-quality-improvement-study
#1
James K Kim, Amanda Kumar, Neda Sadeghi, Michael Shaughnessy, Jeff Gadsden, Karen Nielsen, Steve Melton, Stephen Klein
No abstract text is available yet for this article.
November 2017: Regional Anesthesia and Pain Medicine
https://www.readbyqxmd.com/read/29053047/perineural-spread-of-basosquamous-carcinoma-to-the-orbit-cavernous-sinus-and-infratemporal-fossa
#2
Alec L Amram, William J Hertzing, Stacy V Smith, Patricia Chévez-Barrios, Andrew G Lee
Basosquamous carcinoma is a rare, highly aggressive variant of basal cell carcinoma with elevated rates of recurrence, perineural invasion, and metastasis. We describe a patient who presented with unilateral complete ophthalmoplegia, ptosis, optic neuropathy, and trigeminal neuropathy due to perineural intracranial invasion of nasal basosquamous carcinoma via the sphenopalatine fossa to the cavernous sinus, orbit, and infratemporal fossa. To our knowledge, this is the first reported case of basosquamous carcinoma with perineural invasion involving the cavernous sinus in the English language ophthalmic literature...
October 20, 2017: Orbit
https://www.readbyqxmd.com/read/29052070/the-feasibility-of-laparoscopic-rectal-resection-in-patients-undergoing-reoperation-after-transanal-endoscopic-microsurgery-tem
#3
M Ortenzi, R Ghiselli, A Paolucci, M Guerrieri
BACKGROUND: The success of transanal endoscopic microsurgery (TEM) for early rectal cancer depends on proper indications and strict patient selection. When unfavorable pathologic features are identified after TEM operation, total mesorectal excision is recommended to minimize the risk of recurrence. In this study, data were collected in a retrospective series of patients to determine the results of laparoscopic reoperation after TEM. METHODS: All patients underwent an accurate rectal-digital examination and clinical tumor staging by transanal endosonography, CT, and/or MRI...
October 19, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/29046795/comparison-of-clinicopathological-characteristics-between-cirrhotic-and-non-cirrhotic-patients-with-intrahepatic-cholangiocarcinoma-a-large-scale-retrospective-study
#4
Lei Yuan, Xianwu Luo, Xinyuan Lu, Bin Yi, Kaijian Chu, Quanyu Cai, Xiaoqing Jiang
The effect of cirrhosis on the characteristics of intrahepatic cholangiocarcinoma (ICC) has not been fully elucidated. The purpose of this study was to investigate how cirrhosis affects the clinicopathological characteristics and survival of surgically treated ICC patients. A total of 1,312 ICC patients surgically treated between January 2007 and December 2011 at a single institution were retrospectively reviewed and the clinicopathological data were compared between cirrhotic and non-cirrhotic patients. Univariate and multivariate analyses were performed to identify significant and independent prognostic factors in this cohort...
October 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/29043004/efficacy-of-perineural-dexamethasone-with-ropivacaine-in-adductor-canal-block-for-post-operative-analgesia-in-patients-undergoing-total-knee-arthroplasty-a-randomized-controlled-trial
#5
Cun-Jin Wang, Feng-Yun Long, Liu-Qing Yang, You-Jing Shen, Fang Guo, Tian-Feng Huang, Ju Gao
Adductor canal block (ACB) is an effective analgesic alternative to femoral nerve block after total knee arthroplasty (TKA). The aim of the present study was to investigate whether addition of dexamethasone to ropivacaine for ACB is able to prolong analgesia and reduce pain. Study participants were randomized into groups receiving ACB with either 0.5% ropivacaine + normal saline (control group; n=93) or 0.5% ropivacaine + 8 mg dexamethasone (dexamethasone group; n=93). All patients were subjected to identical peri-operative management...
October 2017: Experimental and Therapeutic Medicine
https://www.readbyqxmd.com/read/29042709/derivation-and-basic-characterization-of-colorectal-carcinoma-primary-cell-lines
#6
Lukas Krbal, Jiri Soukup, Stanislav John, Veronika Hanusova
BACKGROUND: Colorectal carcinoma is one of the most common malignancies in western countries. Among different approaches to its research, primary cancer cell lines can play an important role. AIM: The main purposes of this study were: 1) to establish an effective and reproducible method of colorectal cancer cell isolation and cultivation from primary tumours and lymph node metastases and 2) to elucidate the biological features of the tumours favouring successful cell cultivation...
October 17, 2017: Biomedical Papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia
https://www.readbyqxmd.com/read/29036728/a-retrospective-study-evaluating-the-effect-of-low-doses-of-perineural-dexamethasone-on-ropivacaine-brachial-plexus-peripheral-nerve-block-analgesic-duration
#7
Gregory D Schnepper, Benjamin I Kightlinger, Yunyun Jiang, Bethany J Wolf, Eric D Bolin, Sylvia H Wilson
Objective: Examination of the effectiveness of perineural dexamethasone administered in very low and low doses on ropivacaine brachial plexus block duration. Design: Retrospective evaluation of brachial plexus block duration in a large cohort of patients receiving peripheral nerve blocks with and without perineural dexamethasone in a prospectively collected quality assurance database. Setting: A single academic medical center. Methods: A total of 1,942 brachial plexus blocks placed over a 16-month period were reviewed...
September 23, 2017: Pain Medicine: the Official Journal of the American Academy of Pain Medicine
https://www.readbyqxmd.com/read/29033776/carbohydrate-antigen-19-9-positive-gastric-adenocarcinoma-autopsy-findings-and-review-of-the-literature
#8
Tan Wang, Yoko Matsuda, Atsuko Seki, Keisuke Nonaka, Mototsune Kakizaki, Daita Kaneda, Junko Takahashi-Fujigasaki, Shigeo Murayama, Tomio Arai
Carbohydrate antigen 19-9 (CA19-9) is a well-known tumor marker for pancreatobiliary cancer, and several studies have shown that an elevated serum CA19-9 level is associated with more aggressive biological behavior in gastric cancer (GC). However, the clinicopathological characteristics of CA19-9-positive GC remain unclear. We herein report an autopsy case of CA19-9-positive GC in an 84-year-old man who was admitted to our hospital because of paralysis and anemia. Autopsy revealed an ulcerative-invasive tumor measuring 72 × 60 mm in the anterior wall of the gastric body...
September 2017: Case Reports in Gastroenterology
https://www.readbyqxmd.com/read/29033003/clinicopathological-parameters-affecting-nodal-yields-in-patients-with-oral-squamous-cell-carcinoma-receiving-selective-neck-dissection
#9
Ali-Farid Safi, Martin Kauke, Andrea Grandoch, Hans-Joachim Nickenig, Uta Drebber, Joachim Zöller, Matthias Kreppel
INTRODUCTION: Nodal yield has been demonstrated as a very promising marker for the prognostic outcome of patients with oral squamous cell carcinoma. However, studies on the importance of clinicopathological factors affecting the number of resected lymph nodes are rare, especially for patients without pathologically proven cervical lymph nodes. MATERIAL AND METHODS: Retrospective chart review of 264 patients with treatment naive oral squamous cell carcinoma and histopathologically proven negative cervical lymph node status, who received selective neck dissection of levels I-III/IV...
September 10, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/29029502/clinicopathologic-implications-of-the-mir-197-pd-l1-axis-in-oral-squamous-cell-carcinoma
#10
Hyein Ahn, Jeong Mi Yang, Hyojin Kim, Jin-Haeng Chung, Soon-Hyun Ahn, Woo-Jin Jeong, Jin Ho Paik
Immune escape of a tumor from tumor-infiltrating lymphocytes (TILs) is induced by PD-L1, which is suppressed by miR-197. We investigated the clinicopathologic implications of the miR-197/PD-L1 axis and its effects on TILs and the clinicopathologic features of oral squamous cell carcinoma (OSCC). We used RT-PCR and immunohistochemistry in 68 OSCC patients to analyze the correlations between tumoral expression of miR-197 and PD-L1 and the degree of tumoral invasion by TILs (CD3+, CD4+, CD8+, PD-1+, FoxP3+, and CD20+ lymphocytes)...
September 12, 2017: Oncotarget
https://www.readbyqxmd.com/read/29026716/benign-recurrent-pleomorphic-adenoma-of-the-parotid-gland-with-perineural-space-invasion
#11
EDITORIAL
Luca Roncati, Antonio Maiorana
No abstract text is available yet for this article.
September 2017: Chonnam Medical Journal
https://www.readbyqxmd.com/read/29026354/novel-regional-techniques-for-total-knee-arthroplasty-promote-reduced-hospital-length-of-stay-an-analysis-of-106-patients
#12
Salman Thobhani, Lauren Scalercio, Clint E Elliott, Bobby D Nossaman, Leslie C Thomas, Dane Yuratich, Kim Bland, Kristie Osteen, Matthew E Patterson
BACKGROUND: Novel regional techniques, including the adductor canal block (ACB) and the local anesthetic infiltration between the popliteal artery and capsule of the knee (IPACK) block, provide an alternative approach for controlling pain following total knee arthroplasty (TKA). This study compared 3 regional techniques (femoral nerve catheter [FNC] block alone, FNC block with IPACK, and ACB with IPACK) on pain scores, opioid consumption, performance during physical therapy, and hospital length of stay in patients undergoing TKA...
2017: Ochsner Journal
https://www.readbyqxmd.com/read/29023981/4-bp-insertion-deletion-rs3783553-polymorphism-within-the-3-utr-of-il1a-contributes-to-the-risk-of-prostate-cancer-in-a-sample-of-iranian-population
#13
Mohammad Hashemi, Gholamreza Bahari, Shamim Sarhadi, Ebrahim Eskandari, Behzad Narouie, Mohsen Taheri, Saeid Ghavami
Growing evidence demonstrated the presence of an association between IL1A rs3783553 polymorphism and the risk of various cancers. We aimed to evaluate whether the 4-bp insertion/deletion polymorphism (rs3783553) within the 3' untranslated region (3'UTRs) of IL1A was associated to the risk of prostate cancer (PCa) in a sample of Iranian population. A case-control study, including 150 prostate cancer patients and 155 healthy men, was done to examine the possible association between IL1A 4-bp ins/del polymorphism and PCa risk in a sample of southeast Iranian population...
October 11, 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/29018181/perineural-infiltration-as-a-prognostic-factor-in-surgically-treated-gallbladder-cancer-a-single-center-experience-and-literature-review
#14
Claudio Francesco Feo, Maria Laura Cossu, Giorgio Carlo Ginesu, Alessandro Fancellu, Antonio Mario Scanu, Nadia Piras, Giuseppe Cherchi, Antonio Cossu, Giovanni Sotgiu, Marco Pazzona, Alberto Porcu
INTRODUCTION: Gallbladder cancer (GBC) is the most incident cancer of the biliary tract with only 5-13% of the sufferers surviving for five years. The aim of this study was to evaluate the prognostic role of perineural invasion (PNI) and its association with several clinicopathological variables in a cohort of surgically treated patients, and through a comprehensive review of the scientific literature. MATERIALS AND METHODS: Twenty-five consecutive patients submitted to curative surgery for GBC from 2008 through 2016 were enrolled...
October 4, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28991082/a-distal-resection-margin-of-%C3%A2-1%C3%A2-mm-and-rectal-cancer-recurrence-after-sphincter-preserving-surgery-the-role-of-a-positive-distal-margin-in-rectal-cancer-surgery
#15
Wei-Gen Zeng, Meng-Jia Liu, Zhi-Xiang Zhou, Zhen-Jun Wang
BACKGROUND: There is little information about the prognostic value of a microscopically positive distal margin in patients who have rectal cancer. OBJECTIVE: We aimed to investigate the influence of a distal margin of ≤1 mm on oncologic outcomes after sphincter-preserving resection for rectal cancer. DESIGN: This is a retrospective cohort study. SETTINGS: The study was conducted at 2 hospitals. PATIENTS: A total of 6574 patients underwent anterior resection for rectal cancer from January 1999 to December 2014; 97 (1...
November 2017: Diseases of the Colon and Rectum
https://www.readbyqxmd.com/read/28987674/accuracy-of-mr-neurography-in-the-diagnosis-of-brachial-plexopathy
#16
Julia Crim, Kevin Ingalls
OBJECTIVE: To assess the accuracy of MR neurography (MRN) for the diagnosis for brachial plexopathy. MATERIALS AND METHODS: Forty-three 43 consecutive cases or MRN with electrodiagnostic study correlation were reviewed independently by 2 readers. Established diagnostic criteria were employed: increased signal intensity, enlargement, loss of fascicular pattern, perineural edema and enhancement after administration of gadolinium contrast. An additional 37 cases without electrodiagnostic correlation were included in a second portion of the study, which evaluated interobserver variability...
October 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28984346/do-the-well-known-prognostic-parameters-in-pancreatic-ductal-adenocarcinoma-really-reflect-survival
#17
Sonay Kuş Öztürk, Esra Erden
OBJECTIVE: Pancreatic ductal adenocarcinoma is an aggressive tumor with short survival. In this study we aimed to investigate the effect of well-known prognostic parameters on survival in these tumors. MATERIAL AND METHOD: A total of 56 pancreatic ductal adenocarcinoma cases diagnosed between 2005 and 2014 were included in the study. Survival data were obtained and histopathological parameters were re-evaluated in each patient. RESULTS: Tumor size (p=0...
October 6, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28984303/analysis-of-clinically-relevant-somatic-mutations-in-high-risk-head-and-neck-cutaneous-squamous-cell-carcinoma
#18
Catherine Zilberg, Matthew Weicai Lee, Bing Yu, Bruce Ashford, Spiridoula Kraitsek, Marie Ranson, Kerwin Shannon, Mark Cowley, N Gopalakrishna Iyer, Carsten E Palme, Sydney Ch'ng, Tsu-Hui Hubert Low, Sandra O'Toole, Jonathan R Clark, Ruta Gupta
Cutaneous squamous cell carcinoma is the second most prevalent malignancy, most frequently occurring in the head and neck (head and neck cutaneous squamous cell carcinoma). Treatment of locally advanced or metastatic disease is associated with functional morbidity and disfigurement. Underlying genetic mechanisms are poorly understood. Targeted sequencing of 48 clinically relevant genes was performed on DNA extracted from formalin-fixed and paraffin-embedded high-risk primary head and neck cutaneous squamous cell carcinomas that remained non-metastatic at minimum follow-up of 24 months...
October 6, 2017: Modern Pathology: An Official Journal of the United States and Canadian Academy of Pathology, Inc
https://www.readbyqxmd.com/read/28984139/neurological-improvement-of-perineural-and-leptomeningeal-spread-of-squamous-cell-carcinoma-treated-with-intrathecal-chemotherapy-and-systemic-egfr-inhibition
#19
Vincent Alexander van Vugt, Marlon Garzo Saria, Andres Javier, Navin Kesari, Tiffany Turpin, Santosh Kesari
Squamous cell carcinoma (SCC) is a common cancer of the skin. Risk factors include fair skin, excessive sun and ultraviolet light exposure, and history of xeroderma pigmentosa. Perineural invasion (PNI), an uncommon manifestation of SCC, involves microscopic tumor cells invading various layers of the nerve sheath. It is associated with a poorer prognosis. Standard treatment for PNI includes radiation therapy. Here, we describe a case an older gentleman with a history of SCC with PNI successfully treated with erlotinib and intrathecal chemotherapy...
October 6, 2017: CNS Oncology
https://www.readbyqxmd.com/read/28984108/colonization-contamination-or-infection-in-perineural-catheters-how-to-discriminate
#20
Anselmo Caricato, Massimo Antonelli
No abstract text is available yet for this article.
October 4, 2017: Minerva Anestesiologica
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