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Adjacent Segment

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https://www.readbyqxmd.com/read/27919706/extreme-lateral-lumbar-interbody-fusion-surgical-technique-outcomes-and-complications-after-a-minimum-of-one-year-follow-up
#1
I Domínguez, R Luque, M Noriega, J Rey, J Alia, F Marco-Martínez
«Minimally invasive» techniques have been recently been developed in order to achieve good clinical results with a low incidence of complications. The extralateral interbody fusion or direct transpsoas is a minimally invasive anterior arthrodesis. A total of 97 patients with 138 segments received surgery between May 2012 and May 2015. The follow-up was from 12-44 months. The mean age was 68 years (41-86). The most common cause of intervention was the adjacent segment (30%), deformity (22%), and lumbar disc disease (21%)...
December 2, 2016: Revista Española de Cirugía Ortopédica y Traumatología
https://www.readbyqxmd.com/read/27919246/adjacent-sequences-disclose-potential-for-intra-genomic-dispersal-of-satellite-dna-repeats-and-suggest-a-complex-network-with-transposable-elements
#2
Eva Satović, Tanja Vojvoda Zeljko, Andrea Luchetti, Barbara Mantovani, Miroslav Plohl
BACKGROUND: Satellite DNA (satDNA) sequences are typically arranged as arrays of tandemly repeated monomers. Due to the similarity among monomers, their organizational pattern and abundance, satDNAs are hardly accessible to structural and functional studies and still represent the most obscure genome component. Although many satDNA arrays of diverse length and even single monomers exist in the genome, surprisingly little is known about transition from satDNAs to other sequences. Studying satDNA monomers at junctions and identifying DNA sequences adjacent to them can help to understand the processes that (re)distribute satDNAs and significance that evolution of these sequence elements might have in creating the genomic landscape...
December 6, 2016: BMC Genomics
https://www.readbyqxmd.com/read/27916038/-mid-to-long-term-outcomes-of-cervical-disc-arthroplasty-for-symptomatic-cervical-disc-disease-a-meta-analysis
#3
S L Kan, B Yang, G Z Ning, S J Gao, J C Sun, S Q Feng
Objective: To compare the benefits and harms of cervical disc arthroplasty (CDA) with anterior cervical discectomy and fusion(ACDF) for symptomatic cervical disc disease at mid- to long-term follow-up. Methods: Electronic searches were made in PubMed, EMBASE, and the Cochrane Library for randomized controlled trials with at least 48 moths follow-up.Outcomes were reported as relative risk or standardized mean difference.Meta-analysis was carried out using Revman version 5.3 and Stata version 12.0. Results: Seven trials were included, involving 2 302 participants...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27916034/-the-mid-to-long-term-effect-of-wallis-lumbar-interspinous-dynamic-stabilization-on-the-adjacent-segment-degeneration
#4
X Yuan, C Kong, X M Chen, L B Cui, S J Xu, Y D Liu
Objective: To explore the mid- to long-term effect of Wallis interspinous dynamic stabilization system on the adjacent segment degeneration. Methods: From March 2009 to June 2010, in Department of Orthopedics, Beijing Luhe Hospital, Capital Medical University, 24 patients with L4-5 monosegmental lumbar disc herniation were treated with posterior lumbar decompression combined with Wallis interspinous dynamic fixation. Clinical outcomes were evaluated with visual analogue score (VAS) (back pain), VAS (leg pain) and oswestry disability index (ODI) score...
December 1, 2016: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
https://www.readbyqxmd.com/read/27914637/redo-thoracoabdominal-aortic-aneurysm-repair-a-single-center-experience-over-25%C3%A2-years
#5
Rana O Afifi, Harleen K Sandhu, Amy E Trott, Tom C Nguyen, Charles C Miller, Anthony L Estrera, Hazim J Safi
BACKGROUND: Aortic disease is a lifelong, progressive illness that may require repeated intervention over time. We reviewed our 25-year experience with open redo thoracoabdominal aortic aneurysm (TAAA) and descending thoracic aortic aneurysm (DTAA) repair. Our objectives were to determine patient outcomes after redo repair of DTAA/TAAA and compare them with nonredo repair. We also attempted to identify the risk factors for poor outcome. METHODS: We reviewed all open redo TAAA and DTAA repairs between 1991 and 2014...
November 30, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27906951/changes-in-neuroglial-activity-in-multiple-spinal-segments-after-caudal-epidural-pulsed-radiofrequency-in-a-rat-model-of-lumbar-disc-herniation
#6
Hee Kyung Cho, Jae Hoon Kang, So-Yeon Kim, Mi-Jung Choi, Se Jin Hwang, Yun-Woo Cho, Sang-Ho Ahn
BACKGROUND: Herniated lumbar discs can induce sciatica by mechanical compression and/or chemical irritation. It was recently reported that neuroglial cellular activity after pulsed radiofrequency (PRF) application to a single dorsal root ganglion (DRG) attenuated neuroglial activity at the corresponding spinal dorsal horn. Recently, caudal epidural PRF has been used to manage neuropathic pain, but evidence of molecular changes after the administration of caudal epidural PRF to attenuate neuropathic pain is lacking, and it has not been determined whether caudal epidural PRF affects neuroglial activity at different spinal levels...
November 2016: Pain Physician
https://www.readbyqxmd.com/read/27906169/automated-identification-of-mouse-visual-areas-with-intrinsic-signal-imaging
#7
Ashley L Juavinett, Ian Nauhaus, Marina E Garrett, Jun Zhuang, Edward M Callaway
Intrinsic signal optical imaging (ISI) is a rapid and noninvasive method for observing brain activity in vivo over a large area of the cortex. Here we describe our protocol for mapping retinotopy to identify mouse visual cortical areas using ISI. First, surgery is performed to attach a head frame to the mouse skull (∼1 h). The next day, intrinsic activity across the visual cortex is recorded during the presentation of a full-field drifting bar in the horizontal and vertical directions (∼2 h). Horizontal and vertical retinotopic maps are generated by analyzing the response of each pixel during the period of the stimulus...
January 2017: Nature Protocols
https://www.readbyqxmd.com/read/27898049/mecs-vine-%C3%A2-a-new-proximal-sensor-for-segmented-mapping-of-vigor-and-yield-parameters-on-vineyard-rows
#8
Matteo Gatti, Paolo Dosso, Marco Maurino, Maria Clara Merli, Fabio Bernizzoni, Facundo José Pirez, Bonfiglio Platè, Gian Carlo Bertuzzi, Stefano Poni
Ground-based proximal sensing of vineyard features is gaining interest due to its ability to serve in even quite small plots with the advantage of being conducted concurrently with normal vineyard practices (i.e., spraying, pruning or soil tilling) with no dependence upon weather conditions, external services or law-imposed limitations. The purpose of the present work was to test performance of the new terrestrial multi-sensor MECS-VINE(®) in terms of reliability and degree of correlation with several canopy growth and yield parameters in the grapevine...
November 27, 2016: Sensors
https://www.readbyqxmd.com/read/27893561/finite-element-evaluation-of-different-osteosynthesis-variations-that-used-after-segmental-mandibular-resection
#9
Koray Onur Şanal, Bora Özden, Burcu Baş
PURPOSE: The purpose of this study was to evaluate the effect of different reconstruction plates and screw combinations on stress distribution of segmental resected mandibles using finite element analysis. METHODS: Lateral (L) and lateral-central (LC) defects were simulated by a computer aided design modeling. The straight (s) and angular (a) titanium locking reconstruction plates of 2.5 mm (12 holes for L defects and 16 holes for LC defects) were modeled. Each screw was 2...
November 23, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27891069/automatic-segmentation-of-human-cortical-layer-complexes-and-architectural-areas-using-ex-vivo-diffusion-mri-and-its-validation
#10
Matteo Bastiani, Ana-Maria Oros-Peusquens, Arne Seehaus, Daniel Brenner, Klaus Möllenhoff, Avdo Celik, Jörg Felder, Hansjürgen Bratzke, Nadim J Shah, Ralf Galuske, Rainer Goebel, Alard Roebroeck
Recently, several magnetic resonance imaging contrast mechanisms have been shown to distinguish cortical substructure corresponding to selected cortical layers. Here, we investigate cortical layer and area differentiation by automatized unsupervised clustering of high-resolution diffusion MRI data. Several groups of adjacent layers could be distinguished in human primary motor and premotor cortex. We then used the signature of diffusion MRI signals along cortical depth as a criterion to detect area boundaries and find borders at which the signature changes abruptly...
2016: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/27889355/cervical-sagittal-alignment-in-adult-hyperkyphosis-treated-by-posterior-instrumentation-and-in-situ-bending
#11
F Paternostre, Y P Charles, E A Sauleau, J-P Steib
BACKGROUND: In the normal adult spine, a link between thoracolumbar and cervical sagittal alignment exists, suggesting adaptive cervical positional changes allowing horizontal gaze. In patients with thoracic hyperkyphosis, cervical adaptation to sagittal global alignment might be different from healthy individuals. However, this relationship has not clearly been reported in hyperkyphotic deformity. PURPOSE: The purpose of this study was to identify cervical sagittal alignment types observed on radiographs in young adults with thoracic hyperkyphosis...
November 23, 2016: Orthopaedics & Traumatology, Surgery & Research: OTSR
https://www.readbyqxmd.com/read/27880765/mechanisms-for-complex-chromosomal-insertions
#12
Shen Gu, Przemyslaw Szafranski, Zeynep Coban Akdemir, Bo Yuan, Mitchell L Cooper, Maria A Magriñá, Carlos A Bacino, Seema R Lalani, Amy M Breman, Janice L Smith, Ankita Patel, Rodger H Song, Weimin Bi, Sau Wai Cheung, Claudia M B Carvalho, Paweł Stankiewicz, James R Lupski
Chromosomal insertions are genomic rearrangements with a chromosome segment inserted into a non-homologous chromosome or a non-adjacent locus on the same chromosome or the other homologue, constituting ~2% of nonrecurrent copy-number gains. Little is known about the molecular mechanisms of their formation. We identified 16 individuals with complex insertions among 56,000 individuals tested at Baylor Genetics using clinical array comparative genomic hybridization (aCGH) and fluorescence in situ hybridization (FISH)...
November 2016: PLoS Genetics
https://www.readbyqxmd.com/read/27879576/analysis-of-sagittal-parameters-in-patients-undergoing-one-or-two-level-closing-wedge-osteotomy-for-correcting-thoracolumbar-kyphosis-secondary-to-ankylosing-spondylitis
#13
Wen-Bin Hua, Yu-Kun Zhang, Yong Gao, Xian-Zhe Liu, Shu-Hua Yang, Xing-Huo Wu, Jing Wang, Cao Yang
STUDY DESIGN: Retrospective analysis of clinical records. OBJECTIVE: To assess and compare the improvement in sagittal balance after one- or two-level closing wedge osteotomy for correcting thoracolumbar kyphosis secondary to ankylosing spondylitis (AS). SUMMARY OF BACKGROUND DATA: Closing wedge osteotomy represents a common approach to correct kyphosis in AS. While several reports have described the outcomes of one- or two-level closing wedge osteotomy in terms of sagittal parameters, data comparing the outcomes of these procedures are scarce...
November 22, 2016: Spine
https://www.readbyqxmd.com/read/27879529/morphometric-study-of-the-vestibular-aqueduct-in-patients-with-enlarged-vestibular-aqueduct
#14
Huiying Lyu, Keguang Chen, Youzhou Xie, Lin Yang, Tianyu Zhang, Peidong Dai
OBJECTIVE: To test whether there are significant differences in the morphologic features of the enlarged vestibular aqueduct (EVA) and its anatomic relationships with adjacent structures between EVA patients with and without other inner ear malformations. METHODS: The morphology of vestibular aqueduct, volume of vestibule, and anatomic location of facial nerve (FN) were compared among 3 groups. Group A, 18 control subjects; group B, 32 EVA patients without other inner ear malformations; group C, 14 EVA patients with other inner ear malformations...
November 23, 2016: Journal of Computer Assisted Tomography
https://www.readbyqxmd.com/read/27878929/ambulatory-glucose-profile-analysis-of-the-juvenile-diabetes-research-foundation-continuous-glucose-monitoring-dataset-applications-to-the-pediatric-diabetes-population
#15
Gregory P Forlenza, Laura L Pyle, David M Maahs, Timothy C Dunn
BACKGROUND: Increased continuous glucose monitor (CGM) use presents both the benefit and burden of increased data for clinicians to rapidly analyze. The ambulatory glucose profile (AGP) is an evolving a universal software report for CGM data analysis. OBJECTIVES/HYPOTHESES: We utilized the Juvenile Diabetes Research Foundation-CGM dataset to evaluate the AGP across a broad spectrum of patients to show how AGP can be used clinically to assist with CGM-related decision making...
November 23, 2016: Pediatric Diabetes
https://www.readbyqxmd.com/read/27876503/cranio-caudal-asymmetries-in-trabecular-architecture-reflect-vertebral-fracture-patterns
#16
Ge Yang, Michele C Battié, Steven K Boyd, Tapio Videman, Yue Wang
Clinically, vertebral fractures often occur in the upper lumbar spine and involve the superior endplate of a vertebra (which is immediately caudal to a disc). Knowledge that the cranial endplate of a disc is thicker and has greater bone mineral density (BMD) than the corresponding caudal endplate helps to explain this phenomenon. In this study, we investigated structural differences in vertebral trabeculae on either side of a lumbar disc to provide further insight into vertebral fracture risk. As the focus is trabecular difference within a spinal motion segment, we define cranial and caudal vertebral trabeculae relative to the disc...
November 19, 2016: Bone
https://www.readbyqxmd.com/read/27875133/bipolar-intracardiac-electrogram-active-interval-extraction-during-atrial-fibrillation
#17
Mohammad Hassan Shariat, Saeed Gazor, Damian Redfearn
OBJECTIVE: We introduce novel methods to identify the active intervals (AIs) of intracardiac electrograms (IEGMs) during complex arrhythmias, such as atrial fibrillation (AF). METHODS: We formulate the AI extraction problem, which consists of estimating the beginning and duration of the AIs, as a sequence of hypothesis tests. In each test, we compare the variance of a small portion of the bipolar IEGM with its adjacent segments. We propose modified general-likelihood-ratio (MGLR) and separating-function-estimation tests; we derive five test statistics (TSs), and show that the AIs can be obtained by threshold crossing the TSs...
November 18, 2016: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/27870867/preserving-posterior-complex-can-prevent-adjacent-segment-disease-following-posterior-lumbar-interbody-fusion-surgeries-a-finite-element-analysis
#18
Yun-Peng Huang, Cheng-Fei Du, Cheng-Kung Cheng, Zheng-Cheng Zhong, Xuan-Wei Chen, Gui Wu, Zhe-Cheng Li, Jin-Duo Ye, Jian-Hua Lin, Li Zhen Wang
OBJECTIVE: To investigate the biomechanical effects of the lumbar posterior complex on the adjacent segments after posterior lumbar interbody fusion (PLIF) surgeries. METHODS: A finite element model of the L1-S1 segment was modified to simulate PLIF with total laminectomy (PLIF-LAM) and PLIF with hemilaminectomy (PLIF-HEMI) procedures. The models were subjected to a 400N follower load with a 7.5-N.m moment of flexion, extension, torsion, and lateral bending. The range of motion (ROM), intradiscal pressure (IDP), and ligament force were compared...
2016: PloS One
https://www.readbyqxmd.com/read/27867080/biomechanical-advantages-of-robot-assisted-pedicle-screw-fixation-in-posterior-lumbar-interbody-fusion-compared-to-free-hand-technique-in-a-prospective-randomized-controlled-trial-perspective-for-patient-specific-finite-element-analysis
#19
Ho-Joong Kim, Kyoung-Tak Kang, Sung-Cheol Park, Bong-Soon Chang, Choon-Ki Lee, Jin S Yeom, Lawrence G Lenke
BACKGROUND CONTEXT: There have been conflicting results regarding the surgical outcome of lumbar fusion surgery using two different techniques between robot-assisted pedicle screw fixation and conventional free-hand technique. In addition, there have been no studies about biomechanical issues between the both techniques. PURPOSE: To investigate biomechanical properties in terms of stress at adjacent segments using robot-assisted pedicle screw insertion technique (robot-assisted minimally invasive posterior lumbar interbody fusion, Rom-PLIF) and free-hand technique (conventional, free-hand, open approach, posterior lumbar interbody fusion, Cop-PLIF) for instrumented lumbar fusion surgery...
November 17, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27865820/adjacent-segment-disease-requiring-reoperation-in-cervical-total-disc-arthroplasty-a-literature-review-and-update
#20
REVIEW
Ki-Eun Chang, Martin H Pham, Patrick C Hsieh
OBJECTIVE: To evaluate the difference in rate of reoperation for adjacent segment disease (ASD) between anterior cervical decompression and fusion (ACDF) and total disc replacement (TDR). METHOD: A systematic review of literature was performed using PubMed, clinicaltrials.gov, and various other search engines. Nine studies met the inclusion criteria and were used to report an estimated overall rate of reoperation secondary to ASD for both ACDF and TDR. RESULTS: Forty-six clinical trials were identified after the initial search, and 9 studies met our inclusion criteria...
November 16, 2016: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
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