keyword
MENU ▼
Read by QxMD icon Read
search

Osteoporosis calcium

keyword
https://www.readbyqxmd.com/read/29452318/bone-metabolic-markers-in-the-clinical-assessment-of-patients-with-superior-semicircular-canal-dehiscence-treated-with-middle-fossa-craniotomy
#1
Thien Nguyen, Carlito Lagman, John P Sheppard, Courtney Duong, Vera Ong, Jessica Poon, Yasmine Alkhalid, Daniel Azzam, Prasanth Romiyo, Giyarpuram N Prashant, Quinton Gopen, Isaac Yang
BACKGROUND: Superior semicircular canal dehiscence (SSCD) is a bony defect in the osseous shell of the petrous temporal bone. The pathophysiological association between osteoporosis and SSCD remains poorly understood. We aim to investigate the relationships between serum calcium, 25-hydroxyvitamin D, and thyroid stimulating hormone levels, and symptoms in adult patients with SSCD treated through a middle fossa craniotomy. METHODS: Patient demographics and clinical parameters were collected...
February 13, 2018: World Neurosurgery
https://www.readbyqxmd.com/read/29451816/effects-of-teriparatide-on-morphology-of-aortic-calcification-in-aged-hyperlipidemic-mice
#2
Jeffrey J Hsu, Jinxiu Lu, Soban Umar, Jason T Lee, Rajan Kulkarni, Yichen Ding, Chih-Chiang Chang, Tzung K Hsiai, Akishige Hokugo, Ioannis Gkouveris, Sotirios Tetradis, Ichiro Nishimura, Linda L Demer, Yin Tintut
Calcific aortic vasculopathy correlates with bone loss in osteoporosis in an age-independent manner. Prior work suggests that teriparatide, the bone anabolic treatment for postmenopausal osteoporosis, may inhibit onset of aortic calcification. Whether teriparatide affects progression of pre-existing aortic calcification, widespread among this patient population, is unknown. Female apolipoprotein E-deficient mice were aged for over one year to induce aortic calcification, treated for 4.5 weeks with daily injections of control vehicle (PBS), teriparatide 40 µg/kg (PTH40) or 400 µg/kg (PTH400), and assayed for aortic calcification by micro-computed tomography (microCT) before and after treatment...
February 16, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29451049/the-increase-in-bone-mineral-density-by-bisphosphonate-with-active-vitamin-d-analogue-is-associated-with-the-serum-calcium-level-within-the-reference-interval-in-postmenopausal-osteoporosis
#3
Mayuko Kinoshita, Muneaki Ishijima, Haruka Kaneko, Lizu Liu, Masashi Nagao, Ryo Sadatsuki, Shinnosuke Hada, Hitoshi Arita, Takako Aoki, Makoto Yamanaka, Hidetoshi Nojiri, Yuko Sakamoto, Akifumi Tokita, Kazuo Kaneko
OBJECTIVES: To examine the factors associated with increase in lumbar spine bone mineral density (LS-BMD) by bisphosphonates (BPs) with active vitamin D analogue (aVD). METHODS: Two independent postmenopausal osteoporotic patients treated by BPs with aVD for 24 months (Study1:n = 93,Study2:n = 99) were retrospectively analyzed. RESULTS: In Study1, LS-BMD of the patients significantly increased for 24m (5.4%,p<0.001). A multiple regression analysis among baseline characteristics revealed that serum calcium (sCa:8...
February 16, 2018: Modern Rheumatology
https://www.readbyqxmd.com/read/29440877/psychometric-properties-and-assessment-of-the-osteoporosis-health-belief-scale-among-the-general-arabic-population
#4
Mohanad Naji Sahib
Background: Any educational program should be implemented with a good understanding of the population's beliefs. Therefore, the aims of this study were to validate the Arabic version of the Osteoporosis Health Belief Scale (OHBS-A) and assess the osteoprotective attitude among the Iraqi population. Methods: A cross-sectional design, with a random cluster sampling method from the community, was used. The forward-backward-forward translation method was used to translate the questionnaire from English to Arabic...
2018: Patient Preference and Adherence
https://www.readbyqxmd.com/read/29440373/calcium-supplementation-in-osteoporosis-useful-or-harmful
#5
Iacopo Chiodini, Mark J Bolland
Osteoporosis and fragility fractures are important social and economic problems worldwide and are due to both the loss of bone mineral density and sarcopenia. Indeed, fragility fractures are associated with increased disability, morbidity and mortality. It is known that a normal calcium balance together with a normal vitamin D status is important for maintaining well-balanced bone metabolism and for many years calcium and vitamin D has been considered crucial in the prevention and treatment of osteoporosis...
February 12, 2018: European Journal of Endocrinology
https://www.readbyqxmd.com/read/29439698/a-retrospective-analysis-of-bone-mineral-status-in-patients-requiring-spinal-surgery
#6
Tobias Schmidt, Katharina Ebert, Tim Rolvien, Nicola Oehler, Jens Lohmann, Luca Papavero, Ralph Kothe, Michael Amling, Florian Barvencik, Haider Mussawy
BACKGROUND: Impaired bone quality is associated with poor outcome of spinal surgery. The aim of the study was to assess the bone mineral status of patients scheduled to undergo spinal surgery and to report frequencies of bone mineral disorders. METHODS: We retrospectively analyzed the bone mineral status of 144 patients requiring spinal surgery including bone mineral density by dual-energy X-ray absorptiometry (DXA) as well as laboratory data with serum levels of 25-hydroxyvitamin D (25-OH-D), parathyroid hormone, calcium, bone specific alkaline phosphate, osteocalcin, and gastrin...
February 13, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29429033/implementing-a-fracture-liaison-service-open-model-of-care-utilizing-a-cloud-based-tool
#7
S L Greenspan, A Singer, K Vujevich, B Marchand, D A Thompson, Y-J Hsu, D Vaidya, L S Stern, D Zeldow, D B Lee, S Karp, R Recker
PURPOSE: Although half of women and one-quarter of men aged 50 and older will sustain an acute low-trauma fracture, less than a quarter receive appropriate secondary fracture prevention. The goal of this quality improvement demonstration project was to implement a Fracture Liaison Service (FLS) focused on secondary prevention of an osteoporotic fracture in three open health care systems aided by a cloud-based tool. METHODS: The pre-post study design examined the proportion of men and women over age 50 who received appropriate assessment (bone mineral density, vitamin D levels) and treatment (calcium/vitamin D, pharmacologic therapy) in the six months following a recently diagnosed fracture...
February 10, 2018: Osteoporosis International
https://www.readbyqxmd.com/read/29427789/bone-tissue-aging-affects-mineralization-of-cement-lines
#8
Petar Milovanovic, Annika Vom Scheidt, Kathrin Mletzko, George Sarau, Klaus Püschel, Marija Djuric, Michael Amling, Silke Christiansen, Björn Busse
Cement lines are known as thin peripheral boundaries of the osteons. With a thickness below 5 μm their composition of inorganic and organic compounds has been a matter of debate. Here, we hypothesized that cement lines become hypermineralized and their degree of mineralization is not constant but related to the tissue age of the osteon. Therefore, we analyzed the calcium content of osteons and their corresponding cement lines in a range of different tissue ages reflected by osteonal mineralization levels in cadaveric femoral cortical bone of both postmenopausal women with osteoporosis and bisphosphonate-treated cases...
February 7, 2018: Bone
https://www.readbyqxmd.com/read/29425808/metabolism-of-2%C3%AE-2-tetrazol-2-yl-ethyl-1%C3%AE-25-dihydroxyvitamin-d-3-by-cyp24a1-and-biological-activity-of-its-24r-hydroxylated-metabolite
#9
Kaori Yasuda, Eri Tohyama, Masashi Takano, Atsushi Kittaka, Miho Ohta, Shinichi Ikushiro, Toshiyuki Sakaki
Our previous study revealed that the 2α-substituted vitamin D analog 2α-[2-(tetrazol-2-yl)ethyl]-1α,25(OH)2D3(AH-1) exhibited a higher osteocalcin promoter transactivation activity in human osteosarcoma cells and a greater effect on bone mineral density in a rat model of osteoporosis than 1α,25(OH)2D3 without increasing blood calcium concentration. Thus, we hypothesized that AH-1 could be a promising therapeutic agent for osteoporosis without any serious side effects. In this study, we compared the CYP24A1-dependent metabolism of AH-1 with that of 1α,25(OH)2D3...
February 6, 2018: Journal of Steroid Biochemistry and Molecular Biology
https://www.readbyqxmd.com/read/29423363/development-and-psychometric-properties-of-a-calcium-intake-questionnaire-based-on-the-social-cognitive-theory-ciq-sct-for-iranian-women
#10
Mahin Nematollahi, Ahmad Ali Eslami
Background: Osteoporosis is common among women which may be mostly due to the low intake of calcium. This article reports the development, cultural adaptation and psychometric properties of a Calcium Intake Questionnaire based on the social cognitive theory (CIQ-SCT)among Iranian women. Methods: In 2016, this cross-sectional study was carried out among 400 younger than 50 years old women in Isfahan, Iran. After literature review, a preliminary 35-item questionnaire was developed. Then, forward-backward translation and cultural adaptation of the tool was conducted...
2018: Health Promotion Perspectives
https://www.readbyqxmd.com/read/29420674/histomorphometric-study-of-new-bone-formation-comparing-defect-healing-with-three-bone-grafting-materials-the-effect-of-osteoporosis-on-graft-consolidation
#11
Qiao Zhang, Dai Jing, Yufeng Zhang, Richard J Miron
PURPOSE: Bone grafting materials are frequently utilized in oral surgery and periodontology to fill bone defects and augment lost or missing bone. The purpose of this study was to compare new bone formation in bone defects created in both normal and osteoporotic animals loaded with three types of bone grafts from different origins. MATERIALS AND METHODS: Forty-eight female Wistar rats were equally divided into control normal and ovariectomized animals. Bilateral 2...
February 8, 2018: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/29415696/osteoporosis-knowledge-and-beliefs-in-diabetic-patients-a-cross-sectional-study-from-palestine
#12
Ghaith A Ishtaya, Yazan M Anabtawi, Sa'ed H Zyoud, Waleed M Sweileh
BACKGROUND: Osteoporosis is a potential metabolic complication of diabetes mellitus (DM). Therefore, patients with DM should have adequate osteoporosis knowledge and beliefs in order to get engaged in osteoporosis preventive behaviors. The objective of this study was to assess osteoporosis knowledge and beliefs among diabetic patients. METHODS: This was a cross sectional study carried out at Al-Makhfiah governmental primary healthcare unit in Nablus, Palestine from September 2016 to December 2016...
February 7, 2018: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/29394455/retinol-binding-protein-4-is-positively-associated-with-bone-mineral-density-in-osteopenia-and-osteoporosis-type-2-diabetic-patients
#13
Jin Zhou, Nana Huang, Yu Cheng, Liang Li, Wenzhou Jiang, Wei Wang, Daping Wang, Yuxiao Tang, Shulin Chen, Ying Sun
OBJECTIVE: This study intends to study the association between serum retinol-binding protein 4 (RBP4), bone mineral density (BMD), and other bone metabolic related parameters in type 2 diabetic patients older than 50 years, with or without osteopenia or osteoporosis. METHODS: Patients (n = 274 cases) with type 2 diabetes, hospitalized in the Endocrinology Department of Yantai Yuhuangding Hospital from December 2015 to March 2017, were enrolled in the study. The bone mineral density (BMD) was recorded by the dual-energy X-ray absorptiometer, and patients were divided into normal bone mineral density group (148 cases), osteopenia (93 cases), and osteoporosis group (33 cases) group...
February 2, 2018: Clinical Endocrinology
https://www.readbyqxmd.com/read/29393365/gastrodin-protects-mc3t3-e1-osteoblasts-from-dexamethasone-induced-cellular-dysfunction-and-promotes-bone-formation-via-induction-of-the-nrf2-signaling-pathway
#14
Shengye Liu, Tao Fang, Liyu Yang, Zhiguang Chen, Shuai Mu, Qin Fu
Glucocorticoid (GC)-induced osteoporosis (GIO) is one of the most common secondary and iatrogenic forms of osteoporosis. GCs are widely used in clinical therapy and play a key role in the normal regulation of bone remodeling. However, the prolonged and high-dose administration of GCs results in the occurrence of osteoporosis, which is partially due to the dysfunction and apoptosis of osteoblasts and osteocytes. The aim of the present study was to investigate the effects of gastrodin, a natural bioactive compound isolated from the traditional Chinese herbal agent Gastrodia elata, on GC-treated MC3T3‑E1 murine osteoblastic cells...
January 23, 2018: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/29382611/novel-variant-in-sp7-osx-associated-with-recessive-osteogenesis-imperfecta-with-bone-fragility-and-hearing-impairment
#15
Melissa Fiscaletti, Andrew Biggin, Bruce Bennetts, Karen Wong, Julie Briody, Verity Pacey, Catherine Birman, Craig F Munns
Osteogenesis imperfecta (OI) is a connective tissue disorder characterized by low bone density and recurrent fractures with a wide genotypic and phenotypic spectrum. Common features include short stature, opalescent teeth, blue sclerae and hearing impairment. The majority (>90%) of patients with OI have autosomal dominant variants in COL1A1/COL1A2, which lead to defects in type 1 collagen. More recently, numerous recessive variants involving other genes have also been identified. Sp7/Osx gene, is a protein coding gene that encodes a zinc finger transcription factor, osterix, which is a member of the Sp subfamily of sequence-specific DNA-binding proteins...
January 27, 2018: Bone
https://www.readbyqxmd.com/read/29379565/bone-mineral-density-and-bone-metabolism-in-patients-with-duchenne-muscular-dystrophy
#16
Mohammad Barzegar, Elnaz Niknam, Parinaz Habibi, Shadi Shiva, Sanaz Tahmasebi
Objective: Poor bone health with related morbidity is a major problem with Duchene Muscular Dystrophy (DMD). Decreased mobility and long-term corticosteroid therapy are involved in poor bone health in DMD. We investigated bone mineral density and bone metabolism in 30 steroid treated DMD patients and also compared mentioned factors between ambulated and non-ambulated patients. Materials & Methods: In this cross-sectional study, 30 boys (21 patients ambulate and 9 non-ambulate) with documented DMD, according to genetic analysis, were enrolled in 2015...
2018: Iranian Journal of Child Neurology
https://www.readbyqxmd.com/read/29378980/the-prevalence-of-osteoporosis-among-antenatal-clinic-attendees-in-a-rural-mission-hospital-in-south-east-nigeria
#17
P O Ezeonu, U M Agwu, L O Ajah, I B O Dimejesi, L U Ogbonnaya, O U J Umeora, R C Onoh
INTRODUCTION: Osteoporosis is a global public health problem characterized by reduction of bone mineral density (BMD). This study aimed to assess the prevalence of osteoporosis among antenatal clinic attendees in a rural Southeastern hospital. MATERIAL AND METHODS: This was a cross-sectional study of booking Antenatal Clinic Attendees at Mile 4 Catholic Hospital, Abakaliki, between October 2014 and February 2015. The study participants were selected through systematic random sampling...
December 2017: Nigerian Journal of Clinical Practice
https://www.readbyqxmd.com/read/29378534/vertebral-fractures-among-breast-cancer-survivors-in-china-a-cross-sectional-study-of-prevalence-and-health-services-gaps
#18
Evelyn Hsieh, Qin Wang, Renzhi Zhang, Xin Niu, Weibo Xia, Liana Fraenkel, Karl L Insogna, Jing Li, Jennifer S Smith, Chunwu Zhou, You-Lin Qiao, Pin Zhang
BACKGROUND: Breast cancer survivors are at high risk for fracture due to cancer treatment-induced bone loss, however, data is scarce regarding the scope of this problem from an epidemiologic and health services perspective among Chinese women with breast cancer. METHODS: We designed a cross-sectional study comparing prevalence of vertebral fractures among age- and BMI-matched women from two cohorts. Women in the Breast Cancer Survivors cohort were enrolled from a large cancer hospital in Beijing...
January 30, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29377378/evaluation-of-a-multi-modal-direct-to-patient-educational-intervention-targeting-barriers-to-osteoporosis-a-randomized-clinical-trial
#19
Maria I Danila, Ryan C Outman, Elizabeth J Rahn, Amy S Mudano, David T Redden, Peng Li, Jeroan J Allison, Fred A Anderson, Allison Wyman, Susan L Greenspan, Andrea Z LaCroix, Jeri W Nieves, Stuart L Silverman, Ethel S Siris, Nelson B Watts, Michael J Miller, Jeffrey R Curtis, Amy H Warriner, Nicole C Wright, Kenneth G Saag
Osteoporosis treatment rates are declining, even among those with past fractures. Novel, low-cost approaches are needed to improve osteoporosis care. We conducted a parallel group, controlled, randomized clinical trial evaluating a behavioral intervention for improving osteoporosis medication use. A total of 2,684 women with self-reported fracture history after age 45 not using osteoporosis therapy from U.S. Global Longitudinal study of Osteoporosis in Women (GLOW) sites were randomized 1:1 to receive a multi-modal, tailored, direct-to-patient, video intervention vs...
January 26, 2018: Journal of Bone and Mineral Research: the Official Journal of the American Society for Bone and Mineral Research
https://www.readbyqxmd.com/read/29372484/comparative-impact-of-systemic-delivery-of-atorvastatin-simvastatin-and-lovastatin-on-bone-mineral-density-of-the-ovariectomized-rats
#20
Mostafa Shahrezaee, Ahmad Oryan, Farshid Bastami, Sepanta Hosseinpour, Mohammad Hossein Shahrezaee, Amir Kamali
PURPOSE: In addition to lipid-lowering properties, statins have been suggested to affect bone turnover by increasing the osteoblastic bone formation and blocking the osteoclastogenesis. However, there are many controversial reports regarding the beneficial effect of statins on osteoporosis. In this study, we investigated the therapeutic effects of the most important lipophilic statins administered orally for 60 days to the ovariectomized (OVX) female Sprague-Dawley rats and compared the effects on different harvested trabecular and compact bones...
January 25, 2018: Endocrine
keyword
keyword
56985
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"