keyword
MENU ▼
Read by QxMD icon Read
search

Pep hiv

keyword
https://www.readbyqxmd.com/read/29902179/hybrid-stochastic-framework-predicts-efficacy-of-prophylaxis-against-hiv-an-example-with-different-dolutegravir-prophylaxis-schemes
#1
Sulav Duwal, Laura Dickinson, Saye Khoo, Max von Kleist
To achieve the 90-90-90 goals set by UNAIDS, the number of new HIV infections needs to decrease to approximately 500,000 by 2020. One of the 'five pillars' to achieve this goal is pre-exposure prophylaxis (PrEP). Truvada (emtricitabine-tenofovir) is currently the only medication approved for PrEP. Despite its advantages, Truvada is costly and requires individuals to adhere to the once-daily regimen. To improve PrEP, many next-generation regimen, including long-acting formulations, are currently investigated...
June 2018: PLoS Computational Biology
https://www.readbyqxmd.com/read/29899881/human-immunodeficiency-virus-and-hepatitis-b-virus-infection-prevention-following-occupational-exposure-among-staff-at-a-regional-referral-hospital-in-western-kenya
#2
Barbara Kabai Burmen, Joseph Mogunde, Pamela Olilo
Background: Postexposure prophylaxis (PEP) with antiretroviral therapy (ART) and vaccination against hepatitis B virus (HBV) aides in preventing human immunodeficiency virus (HIV) infection and HBV, respectively, from accidental or occupational exposure. We assessed compliance to guidelines for HIV and HBV prevention after occupational exposure among hospital staff at a referral Kenyan hospital. Methods: We reviewed PEP registers for hospital staff reporting an occupational injury at a referral hospital in Western Kenya between January 2011 and December 2012...
2018: International Journal of Preventive Medicine
https://www.readbyqxmd.com/read/29858737/post-exposure-prophylaxis-awareness-knowledge-access-and-use-among-three-populations-in-new-york-city-2016-17
#3
Beryl A Koblin, DaShawn Usher, Vijay Nandi, Hong-Van Tieu, Eddie Bravo, Debbie Lucy, London Miles, Geneva Ortiz, Marcia J Kindlon, Donna M Parisi, Victoria Frye
Post-exposure prophylaxis (PEP) is a cost-effective, but underused HIV prevention strategy. PEP awareness, knowledge, access, and usage was assessed among young men of color who have sex with men (YMSMOC; n = 177), transgender women (TW; n = 182), and cisgender women of color (CWOC; n = 170) in New York City. 59% were aware of PEP: 80% among YMSMOC, 63% among TW and 34% among CWOC (p < 0.001). 13% had ever used PEP. PEP awareness was higher among YMSMOC with a recent HIV test and lower among those with ≥ 4 partners...
June 1, 2018: AIDS and Behavior
https://www.readbyqxmd.com/read/29777425/the-use-of-hiv-post-exposure-prophylaxis-in-forensic-medicine-following-incidents-of-sexual-violence-in-hamburg-germany-a-retrospective-study
#4
Julia Ebert, Jan Peter Sperhake, Olaf Degen, Ann Sophie Schröder
In Hamburg, Germany, the initiation of HIV post-exposure prophylaxis (HIV PEP) in cases of sexual violence is often carried out by forensic medical specialists (FMS) using the city's unique Hamburg Model. FMS-provided three-day HIV PEP starter packs include a combination of raltegravir and emtricitabine/tenofovir. This study aimed to investigate the practice of offering HIV PEP, reasons for discontinuing treatment, patient compliance, and whether or not potential perpetrators were tested for HIV. We conducted a retrospective study of forensic clinical examinations carried out by the Hamburg Department of Legal Medicine following incidents of sexual violence from 2009 to 2016...
May 18, 2018: Forensic Science, Medicine, and Pathology
https://www.readbyqxmd.com/read/29700052/changes-in-recreational-drug-use-drug-use-associated-with-chemsex-and-hiv-related-behaviours-among-hiv-negative-men-who-have-sex-with-men-in-london-and-brighton-2013-2016
#5
Janey Sewell, Valentina Cambiano, Ada Miltz, Andrew Speakman, Fiona C Lampe, Andrew Phillips, David Stuart, Richard Gilson, David Asboe, Nneka Nwokolo, Amanda Clarke, Graham Hart, Alison Rodger
OBJECTIVES: The objective of this study was to compare the prevalence of polydrug use, use of drugs associated with chemsex, specific drug use, and HIV-related behaviours, between two time periods , using two groups of HIV-negative men who have sex with men (MSM) attending the same sexual health clinics in London and Brighton, in two consecutive periods of time from 2013 to 2016. METHODS: Data from MSM in the cross-sectional Attitudes to and Understanding Risk of Acquisition of HIV (AURAH) study (June 2013 to September 2014) were compared with baseline data from different MSM in the prospective cohort study Attitudes to and Understanding Risk of Acquisition of HIV over Time (AURAH2) (November 2014 to April 2016)...
April 26, 2018: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/29676342/audit-of-prevention-of-mother-to-child-transmission-programme-interventions-in-hiv-exposed-children-at-national-hospital-abuja-nigeria
#6
Mariya Mukhtar-Yola, Adekunle Tolulope Otuneye, Amsa Baba Mairami, Yewande Wey, Vincent Nwatah, Lamidi Isah Audu
Background: Ninety percentage of children acquire human immunodeficiency virus (HIV) infection in the form of Mother-to-child Transmission (MTCT). In the absence of interventions, transmission rates range from 15% to 45%. This can be reduced to below 5% with effective interventions. The last published national guideline (NG) on prevention of MTCT (PMTCT) was in 2010. Clinical audits are essential in improving the quality of care delivered to patients. Objectives: The study objectives were to determine the rate of MTCT of HIV in exposed infants at a follow-up clinic between 2011 and 2014 and to determine the level of adherence to 2010 NG on the use of highly active antiretroviral therapy (HAART), polymerase chain reaction (PCR) testing, feeding options, antiretroviral (ARV) prophylaxis and the use of co-trimoxazole (CTZ)...
January 2018: Nigerian Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29628512/hot-news-sexually-transmitted-infections-on-the-rise-in-prep-users
#7
Pablo Barreiro
Pre-exposure prophylaxis (PrEP) with oral Truvada (tenofovir plus emtricitabine) is effective at preventing HIV infection in high-risk homosexual men. In the United States, PrEP was approved in 2012 and is reimbursed by Medicaid and the majority of private insurers. The situation is diverse and not uniform in the European Union, being PrEP more widely used in France than in the rest of countries. Concerns have been raised that PrEP use may be accompanied by the phenomena of risk compensation or behavioral disinhibition, whereby PrEP users' perception of decreased risk of HIV acquisition may lead them to engage in overall riskier sexual practices and increase their chances of acquiring sexually transmitted infections (STIs) (Blumenthal, et al...
January 2018: AIDS Reviews
https://www.readbyqxmd.com/read/29625796/sexualised-drug-use-in-the-united-kingdom-uk-a-review-of-the-literature
#8
Claire Edmundson, Ellen Heinsbroek, Rachel Glass, Vivian Hope, Hamish Mohammed, Martin White, Monica Desai
BACKGROUND: Sexualised drug use (SDU) refers to the use of drugs in a sexual context. This includes 'Chemsex'- the use of drugs (specifically crystal methamphetamine, GHB/GBL and mephedrone) before or during planned sexual activity to sustain, enhance, disinhibit or facilitate the experience. Here we aimed to synthesise available UK prevalence data for Chemsex, SDU and the use of Chemsex drugs in an undefined context (CDU) in men who have sex with men (MSM). METHODS: Papers published between January 2007 and August 2017 reporting Chemsex, SDU and/or Chemsex drug use (CDU) prevalence in MSM were identified through PubMed...
May 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29605540/the-management-of-methamphetamine-use-in-sexual-settings-among-men-who-have-sex-with-men-in-malaysia
#9
Sin How Lim, Mohd Akbar, Jeffrey A Wickersham, Adeeba Kamarulzaman, Frederick L Altice
BACKGROUND: The intentional use of illicit drugs for sexual purposes (also known as 'chemsex') is well known within the MSM communities in Malaysia although research in this population is scarce primarily because both drug use and homosexuality are illegal and stigmatised in Malaysia. METHODS: From April to December 2014, interviews were conducted with twenty men (age range 21-43) living in Greater Kuala Lumpur who had sexual intercourse with other men in the past 6 months and who used illicit drugs at least monthly in the past 3 months...
May 2018: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29530543/nurse-led-hiv-pep-program-used-by-men-at-high-risk-for-hiv-seroconversion
#10
Patrick O'Byrne, Paul MacPherson, Lauren Orser
We trialed a nurse-led HIV postexposure prophylaxis (PEP) program in two sexually transmitted infection clinics in Ottawa, Canada. From September 5, 2013 to September 4, 2015, 112 persons sought PEP: 103 were male, of whom 84 were men who have sex with men (MSM). Seventy-two patients (59 MSM) initiated PEP; 11 were diagnosed with HIV: 6 diagnoses occurred during initial assessment (all MSM; 1 also shared injection equipment); 5 MSM were diagnosed with HIV within 1 year of seeking PEP. This level of positivity indicated that, when access is facilitated, individuals at high risk of HIV seek PEP...
February 17, 2018: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29492179/exploring-receipt-of-hiv-pep-counseling-among-women-sexually-assaulted-by-an-intimate-partner
#11
Janice Du Mont, Lily Van, Daisy Kosa, Sheila Macdonald
Among 136 women sexually assaulted by a current or former male intimate partner presenting to hospital-based violence treatment centers, 58 (42.6%) received HIV post-exposure prophylaxis (HIV PEP) counseling by a specially trained sexual assault nurse. We identified factors that were associated with receipt of HIV PEP counseling. Those who received counseling were more likely to have been younger than 25 years of age, single, a student, vaginally penetrated, and have received various other services ( e.g ., STI prophylaxis)...
2018: Open AIDS Journal
https://www.readbyqxmd.com/read/29487471/nurturing-the-continuum-of-hiv-testing-treatment-and-prevention-matrix-cascade-in-reducing-hiv-transmission
#12
Clarence S Yah
Background: Despite the shift in antiretroviral therapy (ARVs) eligibility cascade from CD4 ≤ 200 to CD4 ≤ 350 to CD4 ≤ 500 mm3 , HIV related morbidity and mortality continue to escalate annually, as do HIV infections. The new paradigm of treatment for all HIV positives individual irrespective of CD4 count may significantly reduce HIV and related illnesses. The author assumes that all HIV infected partners should be eligible for HIV treatment and care, irrespective of CD4 count...
November 2017: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/29296104/addressing-the-dual-health-epidemics-of-hiv-and-sexual-abuse-among-children-and-adolescents-in-kenya-uptake-of-hiv-counseling-and-post-exposure-prophylaxis
#13
Carolyne Ajema, Charity Mbugua, Peter Memiah, Camille Wood, Courtney Cook, Ronald Kotut, Lina Digolo
Purpose: Child sexual abuse and HIV are key health challenges in Kenya. In 2015, LVCT Health conducted a study aimed at assessing the quality of HIV-related services offered to child survivors of sexual violence in public health facilities. Materials and methods: A qualitative data collection approach was utilized. Qualitative data were collected through in-depth interviews with 31 providers. Quantitative methods included a retrospective review of 164 records of child survivors of rape who had accessed services 6 months prior to the commencement of the study...
2018: Adolescent Health, Medicine and Therapeutics
https://www.readbyqxmd.com/read/29278971/prevention-strategies-against-hiv-transmission-a-proactive-approach
#14
Antonio J Carrion, Jovan D Miles, Juan F Mosley, Lillian L Smith, April S Prather, Marcus M Gurley, Linh D Phan, Emily C Everton
Human immunodeficiency virus (HIV) has now transformed into a manageable chronic condition. Highly active antiretroviral therapy (HAART) has proven efficacious at controlling the disease progression. Based on compelling evidence, the Department of Health and Human Services (DHHS) and the Infectious Disease Society of America (IDSA) developed guidelines for the management of persons infected with HIV. However, there are approximately 50 000 new cases of HIV in the United States each year. In this article, we review proactive methods to reduce the transmission of HIV, which include reinforcing patient education, gel-coated condoms that destroy HIV, HIV vaccinations, and adequately utilizing pre-exposure prophylaxis (PrEP), and post-exposure prophylaxis (PEP)...
February 2018: Journal of Pharmacy Practice
https://www.readbyqxmd.com/read/29239887/incidence-of-sexually-transmitted-infections-before-and-after-preexposure-prophylaxis-for-hiv
#15
Vinh-Kim Nguyen, Zoë R Greenwald, Helen Trottier, Martha Cadieux, Alexandre Goyette, Mariève Beauchemin, Louise Charest, Danièle Longpré, Stéphane Lavoie, Hermione Gbego Tossa, Réjean Thomas
OBJECTIVE: Use of preexposure prophylaxis (PrEP) for HIV raises concerns about sexually transmitted infection (STI) incidence because of decreased condom use among MSM. This study examines whether PrEP is associated with STIs in the 12 months following PrEP prescription relative to the 12 months prior to PrEP and if STI rates are higher among PrEP users relative to individuals receiving postexposure prophylaxis (PEP). DESIGN: Retrospective cohort study including PrEP users with more than 12 months of follow-up before PrEP prescription and individuals receiving PEP from 2010 to 2015 at Clinique l'Actuel (Montréal, Canada)...
February 20, 2018: AIDS
https://www.readbyqxmd.com/read/29229440/post-exposure-prophylaxis-with-doxycycline-to-prevent-sexually-transmitted-infections-in-men-who-have-sex-with-men-an-open-label-randomised-substudy-of-the-anrs-ipergay-trial
#16
Jean-Michel Molina, Isabelle Charreau, Christian Chidiac, Gilles Pialoux, Eric Cua, Constance Delaugerre, Catherine Capitant, Daniela Rojas-Castro, Julien Fonsart, Béatrice Bercot, Cécile Bébéar, Laurent Cotte, Olivier Robineau, François Raffi, Pierre Charbonneau, Alexandre Aslan, Julie Chas, Laurence Niedbalski, Bruno Spire, Luis Sagaon-Teyssier, Diane Carette, Soizic Le Mestre, Veronique Doré, Laurence Meyer
BACKGROUND: Increased rates of sexually transmitted infections (STIs) have been reported among men who have sex with men. We aimed to assess whether post-exposure prophylaxis (PEP) with doxycycline could reduce the incidence of STIs. METHODS: All participants attending their scheduled visit in the open-label extension of the ANRS IPERGAY trial in France (men aged 18 years or older having condomless sex with men and using pre-exposure prophylaxis for HIV with tenofovir disoproxil fumarate plus emtricitabine) were eligible for inclusion in this open-label randomised study...
March 2018: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/29183270/results-from-the-post-exposure-prophylaxis-pilot-program-p-quad-demonstration-project-in-los-angeles-county
#17
Matthew R Beymer, Ryan M Kofron, Chi-Hong Tseng, Robert K Bolan, Risa P Flynn, Jennifer M Sayles, Mario J Perez, Wilbert C Jordan, Raphael J Landovitz
Post-exposure prophylaxis (PEP) is a promising but under-utilized strategy for HIV prevention in high-risk populations. Between March 2010 and June 2011, two community-based clinics in Los Angeles County provided PEP in a pilot program to 267 unique individuals. Courses were primarily dispensed to men who have sex with men (84%) and consisted overwhelmingly of a three-drug antiretroviral therapy regimen containing two nucleoside reverse transcriptase inhibitors and either an integrase inhibitor (raltegravir) or a boosted protease inhibitor (lopinavir/ritonavir)...
May 2018: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/29174349/a-meta-analysis-of-hiv-postexposure-prophylaxis-among-sexually-assaulted-patients-in-the-united-states
#18
Meredith Scannell, Tiffany Kim, Barbara J Guthrie
Sexual assault (SA) is a major public health problem that leaves patients at risk for HIV. The gold standard of medical treatment for SA patients includes prophylactic treatment to prevent HIV. A meta-analysis was conducted and examined the rates of nonoccupational postexposure prophylaxis (n-PEP) offered to, accepted, and completed by SA patients who presented to emergency departments in the United States. Four points of data were analyzed: (a) SA patients who met the criteria and were offered n-PEP, (b) SA patients who were offered n-PEP and accepted the medication, (c) SA patients who accepted n-PEP treatment and completed at least one follow-up appointment, and (d) SA patients who completed the entire course of n-PEP...
January 2018: Journal of the Association of Nurses in AIDS Care: JANAC
https://www.readbyqxmd.com/read/29108450/comparing-provider-and-client-preferences-for-hiv-prevention-services-in-south-africa-among-men-who-have-sex-with-men
#19
John Shaver, Patrick Sullivan, Aaron Siegler, Alex de Voux, Nancy Phaswana-Mafuya, Linda-Gail Bekker, Stefan D Baral, Andrea L Wirtz, Chris Beyrer, Ben Brown, Rob Stephenson
Combination prevention efforts are now recommended toward reducing HIV incidence among men who have sex with men (MSM). Understanding the perceptions of both MSM and service providers is critical to informing the development of prevention packages and ultimately improving intervention effectiveness. This study assessed the preferences of MSM and health service providers in the administration of HIV-prevention efforts. Qualitative data were gathered from a series of separate MSM and health care provider focus groups in 2 South African cities...
November 2017: Journal of the International Association of Providers of AIDS Care
https://www.readbyqxmd.com/read/29091217/tenofovir-disoproxil-fumarate-emtricitabine-plus-ritonavir-boosted-lopinavir-or-cobicistat-boosted-elvitegravir-as-a-single-tablet-regimen-for-hiv-post-exposure-prophylaxis
#20
A Inciarte, L Leal, E González, A León, C Lucero, J Mallolas, B Torres, M Laguno, J Rojas, M Martínez-Rebollar, A González-Cordón, A Cruceta, J A Arnaiz, J M Gatell, F García
Objectives: To assess HIV-1 post-exposure prophylaxis (PEP) non-completion at day 28, comparing ritonavir-boosted lopinavir versus cobicistat-boosted elvitegravir as a single-tablet regimen (STR), using tenofovir disoproxil fumarate/emtricitabine with both of these therapies. Methods: A prospective, open, randomized clinical trial was performed. Individuals attending the emergency room due to potential sexual exposure to HIV and who met criteria for PEP were randomized 1:3 into two groups receiving either 400/100 mg of lopinavir/ritonavir (n = 38) or 150/150 mg of elvitegravir/cobicistat (n = 119), with both groups also receiving 245/200 mg of tenofovir disoproxil fumarate/emtricitabine...
October 1, 2017: Journal of Antimicrobial Chemotherapy
keyword
keyword
56983
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"