Shuming Zhong, Pan Chen, Shunkai Lai, Yiliang Zhang, Guanmao Chen, Jiali He, Youling Pan, Guixian Tang, Ying Wang, Yanbin Jia
Introduction Suicide in bipolar disorder (BD) is a multifaceted behavior, involving specific neuroendocrine and psychological mechanisms. According to previous studies, we hypothesized that suicidal BD patients may exhibit impaired dynamic functional connectivity (dFC) variability of hippocampal subregions and hypothalamic-pituitary-adrenal (HPA) axis activity, which may be associate with suicide-related personality traits. The objective of our study was to clarify this. Methods Resting-state functional magnetic resonance imaging data were obtained from 79 patients with BD, 39 with suicidal attempt (SA) and 40 without SA, and 35 healthy controls...
September 20, 2023: Neuroendocrinology