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https://www.readbyqxmd.com/read/27902586/neurological-psychological-and-cognitive-disorders-in-patients-with-chronic-kidney-disease-on-conservative-and-replacement-therapy
#1
Silvia Lai, Oriano Mecarelli, Patrizia Pulitano, Roberto Romanello, Leonardo Davi, Alessia Zarabla, Amalia Mariotti, Maria Carta, Giorgia Tasso, Luca Poli, Anna Paola Mitterhofer, Massimo Testorio, Nicla Frassetti, Paola Aceto, Alessandro Galani, Carlo Lai
Chronic kidney disease (CKD) is a highly prevalent condition in the world. Neurological, psychological, and cognitive disorders, related to CKD, could contribute to the morbidity, mortality, and poor quality of life of these patients. The aim of this study was to assess the neurological, psychological, and cognitive imbalance in patients with CKD on conservative and replacement therapy.Seventy-four clinically stable patients affected by CKD on conservative therapy, replacement therapy (hemodialysis (HD), peritoneal dialysis (PD)), or with kidney transplantation (KT) and 25 healthy controls (HC), matched for age and sex were enrolled...
November 2016: Medicine (Baltimore)
https://www.readbyqxmd.com/read/27883317/somatoform-disorders-a-pediatric-experience
#2
Nada Pop-Jordanova, Tatjana Zorcec
Somatization in children consists of the persistent experience and complaints of somatic distress that cannot be fully explained by a medical diagnosis. Working at the Psychophysiological Department at the University Clinic we are dealing with more than 100 children per year manifesting this kind of disorders. The aim of this article is to summarize some specific characteristics of the somatoform disorder in a group of 243 children, mean age 10.31 (± 2.75) years for both genders, selected randomly. The used psychometric instruments are: CBCL, EPQ for children, and MMPI-201 for mothers...
November 1, 2016: Prilozi (Makedonska Akademija Na Naukite i Umetnostite. Oddelenie za Medicinski Nauki)
https://www.readbyqxmd.com/read/27849364/assessment-of-dsm-5-section-ii-personality-disorders-with-the-mmpi-2-rf-in-a-nonclinical-sample
#3
Martin Sellbom, Alexander Smith
The Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008 / 2011 ) is frequently used in clinical practice. However, there has been a dearth of literature on how well this instrument can assess symptoms associated with personality disorders (PDs). This investigation examined a range of hypothesized MMPI-2-RF scales in predicting PD symptoms. We evaluated these associations in a sample of 397 university students who had been administered the MMPI-2-RF and the Structured Clinical Interview for DSM-IV Axis II Disorders-Personality Questionnaire (First, Gibbon, Spitzer, Williams, & Benjamin, 1997 )...
November 16, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27833228/minnesota-multiphasic-personality-inventory-2-profiles-of-patients-with-gender-identity-disorder-requesting-sex-reassignment-surgery
#4
Sagar Karia, Sanhita Jamsandekar, Alpa Alure, Avinash De Sousa, Nilesh Shah
BACKGROUND: Gender identity disorder (GID) is a distressing disorder characterized by a persistent unhappiness with one's own sex and a desire to be of the opposite sex as well as seeking sex reassignment surgery for the same. The aim of the study was to assess the Minnesota Multiphasic Personality Inventory-2 (MMPI-2) profiles in patients with GID and examine differences in the profiles based on original gender of the patients. METHODOLOGY: Twenty-seven patients with GID that fulfilled the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition Text Revision criteria for the same were participants of the study...
September 2016: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/27831901/imaging-matrix-metalloproteinase-activity-in-multiple-sclerosis-as-a-specific-marker-of-leukocyte-penetration-of-the-blood-brain-barrier
#5
Hanna Gerwien, Sven Hermann, Xueli Zhang, Eva Korpos, Jian Song, Klaus Kopka, Andreas Faust, Christian Wenning, Catharina C Gross, Lisa Honold, Nico Melzer, Ghislain Opdenakker, Heinz Wiendl, Michael Schäfers, Lydia Sorokin
The enzymes gelatinase A/matrix metalloproteinase-2 (MMP-2) and gelatinase B/MMP-9 are essential for induction of neuroinflammatory symptoms in experimental autoimmune encephalomyelitis (EAE), a mouse model of multiple sclerosis (MS); in the absence of these enzymes, the disease does not develop. We therefore investigated the cellular sources and relative contributions of MMP-2 and MMP-9 to disease at early stages of EAE induction. We demonstrated that MMP-9 from an immune cell source is required in EAE for initial infiltration of leukocytes into the central nervous system and that MMP-9 activity is a reliable marker of leukocyte penetration of the blood-brain barrier...
November 9, 2016: Science Translational Medicine
https://www.readbyqxmd.com/read/27819465/elucidating-the-validity-of-the-externalizing-spectrum-of-psychopathology-in-correctional-forensic-and-community-samples
#6
Martin Sellbom
Krueger and colleagues (2007) have elaborated on a hierarchical structural model of externalizing psychopathology, with a general overarching factor and 2 residual liability factors reflecting callous-aggression and substance misuse. The current study used an independent set of symptom and behavior indicators (items derived from the Minnesota Multiphasic Personality Inventory-2-Restructured Form) to test alternative models of externalizing. In mixed-sex samples of correctional inmates (n = 42,290), forensic criminal defendants (n = 1,065), and community participants (n = 2,214), a bifactor model based on Krueger, Markon, Patrick, Benning, and Kramer (2007) was associated with better model fit relative to a 1-factor model, 2-factor model, and a bifactor model with 2 random bifactors...
November 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27808558/construct-validity-of-the-mmpi-2-rf-triarchic-psychopathy-scales-in-correctional-and-collegiate-samples
#7
Taylor J Kutchen, Dustin B Wygant, Jessica L Tylicki, Amy M Dieter, Carlo O C Veltri, Martin Sellbom
This study examined the MMPI-2-RF (Ben-Porath & Tellegen, 2008/2011) Triarchic Psychopathy scales recently developed by Sellbom et al. ( 2016 ) in 3 separate groups of male correctional inmates and 2 college samples. Participants were administered a diverse battery of psychopathy specific measures (e.g., Psychopathy Checklist-Revised [Hare, 2003 ], Psychopathic Personality Inventory-Revised [Lilienfeld & Widows, 2005 ], Triarchic Psychopathy Measure [Patrick, 2010 ]), omnibus personality and psychopathology measures such as the Personality Assessment Inventory (Morey, 2007 ) and Personality Inventory for DSM-5 (Krueger, Derringer, Markon, Watson, & Skodol, 2012 ), and narrow-band measures that capture conceptually relevant constructs...
November 3, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27807690/inpatient-treatment-effect-and-minnesota-multiphasic-personality-inventory-characteristics-of-motor-vehicle-collision-injuries-in-a-traditional-korean-medicine-hospital-retrospective-chart-review
#8
Min-Yeong Song, Hee-Guen Jo, Jae-Uk Sul, Seong-Tae Kim, Kil-Joon Bae, Tae-Gwang Kim, Jae-Hong Kim, Jin-Bong Choi
OBJECTIVES: To examine the changes in pain, disability, and quality of life in motor vehicle collision injury (MVCI) patients after treatment with traditional Korean medicine (TKM), and to investigate the psychological characteristics of these patients. METHODS: Forty-one patients with MVCI were treated with TKM including acupuncture, pharmacopuncture, moxibustion, cupping, herbal medication, chuna manual therapy, and physical therapy. Numeric Rating Scale (NRS), Medical Outcomes Study 36-Item Short Form Health Survey (SF-36), Neck Disability Index (NDI), Oswestry Disability Index (ODI), and Lysholm Knee Scoring Scale were assessed at admission and discharge...
November 3, 2016: Chinese Journal of Integrative Medicine
https://www.readbyqxmd.com/read/27789372/waddell-nonorganic-signs-new-evidence-suggests-somatic-amplification-among-outpatient-chronic-pain-patients
#9
Dustin B Wygant, Paul A Arbisi, Kevin J Bianchini, Robert L Umlauf
BACKGROUND CONTEXT: Waddell and colleagues identified a set of 8 non-organic signs in 1980. There has been controversy about their meaning, particularly with respect to their use as validity indicators. PURPOSE: The current study examined the Waddell signs in relation to measures of somatic amplification/over-reporting in a sample of outpatient chronic pain patients. We examined the degree to which these signs were associated with measures of over-reporting. STUDY DESIGN/SETTING: Examined scores on the Waddell signs in relation to over-reporting indicators and various symptoms (somatic symptoms, mood/anxiety, and pain) in an outpatient chronic pain sample...
October 24, 2016: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/27771315/associations-between-psychological-test-results-and-failure-to-proceed-with-bariatric-surgery
#10
Ryan J Marek, Anthony M Tarescavage, Yossef S Ben-Porath, Kathleen Ashton, Leslie J Heinberg, Julie Merrell Rish
BACKGROUND: The reasons why some patients who begin the presurgical process for bariatric surgery fail to complete the procedure are understudied. Previous research implies that psychological factors play a role. OBJECTIVES: To examine whether scores from baseline psychological testing incrementally predict failure to proceed with bariatric surgery beyond demographic information in patients' medical charts and data derived from a clinical interview. SETTING: Cleveland Clinic Bariatric and Metabolic Institute...
September 16, 2016: Surgery for Obesity and related Diseases: Official Journal of the American Society for Bariatric Surgery
https://www.readbyqxmd.com/read/27767344/the-development-of-the-inventory-of-problems-29-a-brief-self-administered-measure-for-discriminating-bona-fide-from-feigned-psychiatric-and-cognitive-complaints
#11
Donald J Viglione, Luciano Giromini, Patricia Landis
This article describes the development of the Inventory of Problems-29 (IOP-29), a new, short, paper-and-pencil, self-administered measure of feigned mental and cognitive disorders. Four clinical comparison simulation studies were conducted. Study 1 (n = 451) selected the items and produced an index of potential feigning. Study 2 (n = 331) scaled this index to produce a probability score, and examined its psychometric properties. Study 3 tested the generalizability of Study 2's findings with 2 additional samples (ns = 128 and 90)...
October 21, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27759415/which-maternal-personality-traits-affect-child-behaviour-during-dental-treatment
#12
A H Arpaci, B Işik, N Cura, B Kaplan, P Bozkurt
AIM: Maternal personality traits affect child dental behaviour and have a potential link with dental treatment methods. This study aims to evaluate which maternal personality traits affect child dental behaviour. MATERIALS AND METHODS: Research was carried out upon 60 children aged between 3-12 years, who had been admitted to our clinic for tooth extraction. All children were evaluated by means of the Frankl Behavior Scale (FBS): degrees I and II represent negative behaviours, while III and IV positive behaviour...
September 2016: European Journal of Paediatric Dentistry: Official Journal of European Academy of Paediatric Dentistry
https://www.readbyqxmd.com/read/27756325/less-is-more-low-expression-of-mt1-mmp-is-optimal-to-promote-migration-and-tumourigenesis-of-breast-cancer-cells
#13
Mario A Cepeda, Jacob J H Pelling, Caitlin L Evered, Karla C Williams, Zoey Freedman, Ioana Stan, Jessica A Willson, Hon S Leong, Sashko Damjanovski
BACKGROUND: Membrane Type-1 Matrix Metalloproteinase (MT1-MMP) is a multifunctional protease implicated in metastatic progression ostensibly due to its ability to degrade extracellular matrix (ECM) components and allow migration of cells through the basement membrane. Despite in vitro studies demonstrating this principle, this knowledge has not translated into the use of MMP inhibitors (MMPi) as effective cancer therapeutics, or been corroborated by evidence of in vivo ECM degradation mediated by MT1-MMP, suggesting that our understanding of the role of MT1-MMP in cancer progression is incomplete...
October 18, 2016: Molecular Cancer
https://www.readbyqxmd.com/read/27752979/an-introduction-to-the-minnesota-multiphasic-personality-inventory-adolescent-restructured-form-mmpi-a-rf
#14
Richard W Handel
The Minnesota Multiphasic Personality Inventory-Adolescent-Restructured Form (MMPI-A-RF; Archer, Handel, Ben-Porath, & Tellegen, 2016) is a new broadband measure of adolescent psychopathology and personality. The MMPI-A-RF is the adolescent counterpart of the MMPI-2-RF (Ben-Porath & Tellegen, 2008/2011). The goal of the MMPI-2-RF development project was to capture the clinically significant substance of the MMPI-2 item pool with a psychometrically sound measure linked to contemporary models of personality and psychopathology (Ben-Porath & Tellegen, 2008/2011)...
December 2016: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/27743382/mmp-inhibitor-ilomastat-induced-amoeboid-like-motility-via-activation-of-the-rho-signaling-pathway-in-glioblastoma-cells
#15
Shaofeng Yan, Hao Xue, Ping Zhang, Xiao Han, Xing Guo, Guang Yuan, Lin Deng, Gang Li
Matrix metalloproteinases (MMPs) play the important role in the process of glioblastoma cell invasion through 3D matrices. However, the effects of MMP inhibitors used in the treatment of malignant gliomas are unsatisfactory. The aim of this study was to explore the reason and mechanism by which cells move through the dense extracellular matrix without proteolysis. The results showed that MMP inhibitor (MMPI), Ilomastat, induced glioma cells to have an amoeboid-like morphology with invasive ability. Moreover, the RhoA/Rho kinase (ROCK)/myosin light chain (MLC) signal is involved in the MMPI-induced movement mode switch, and RhoA activation is dependent on P115RhoGEF...
October 14, 2016: Tumour Biology: the Journal of the International Society for Oncodevelopmental Biology and Medicine
https://www.readbyqxmd.com/read/27715316/using-the-research-domain-criteria-framework-to-explore-associations-between-mmpi-2-rf-constructs-and-physiological-variables-assessed-by-eye-tracker-technology
#16
David M McCord, Margaret C Achee, Elissa M Cannon, Tiffany M Harrop, William D Poynter
The National Institute of Mental Health has proposed a paradigm shift in the conceptualization of psychopathology, abandoning the traditional categorical model in favor of one based on hierarchically organized dimensional constructs (Insel et al., 2010 ). One explicit goal of this initiative, the Research Domain Criteria (RDoC) project, is to facilitate the incorporation of newly available neurobiologic variables into research on psychopathology. The Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008/2011 ) represents a similar paradigm shift, also adopting a hierarchical arrangement of dimensional constructs...
October 7, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27715314/using-mmpi-2-rf-correlates-to-elucidate-the-pcl-r-and-its-four-facets-in-a-sample-of-male-forensic-psychiatric-patients
#17
Evelyn Klein Haneveld, Jan H Kamphuis, Wineke Smid, Johnathan D Forbey
This study documents the associations between the MMPI-2-RF (Ben-Porath & Tellegen, 2008 ) scale scores and the Psychopathy Checklist Revised (PCL-R; Hare, 2003 ) facet scores in a forensic psychiatric sample. Objectives were to determine how the MMPI-2-RF scales might enhance substantive understanding of the nature of the 4 PCL-R facets and to discern possible implications for the treatment of psychopathic patients. A sample of 127 male forensic psychiatric offenders admitted to a Dutch forensic psychiatric hospital completed the PCL-R and the MMPI-2...
October 7, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27669361/examination-of-mmpi-2-rf-substantive-scales-as-indicators-of-acute-suicidal-affective-disturbance-components
#18
Megan L Rogers, Joye C Anestis, Tiffany M Harrop, Matthew Schneider, Theodore W Bender, Fallon B Ringer, Thomas E Joiner
A new suicide-specific diagnostic entity, acute suicidal affective disturbance (ASAD), was recently proposed to fill a void in the nomenclature. Although several studies have examined the reliability, validity, and potential clinical utility of ASAD, no studies have examined personality indicators of ASAD. This study sought to examine the association between personality and psychopathology factors, as assessed by the Minnesota Multiphasic Personality Inventory-2-Revised Form (MMPI-2-RF), and constructs that comprise ASAD in a sample of 554 psychiatric outpatients who completed all measures prior to their intake appointments...
September 26, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27661293/examining-the-construct-validity-of-the-mmpi-2-rf-interpersonal-functioning-scales-using-the-computerized-adaptive-test-of-personality-disorder-as-a-comparative-framework
#19
Annabel O Franz, Tiffany M Harrop, David M McCord
This study aimed to examine the construct validity of the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF) interpersonal functioning scales (Ben-Porath & Tellegen, 2008/2011 ) using as a criterion measure the Computerized Adaptive Test of Personality Disorder-Static Form (CAT-PD-SF; Simms et al., 2011 ). Participants were college students (n = 98) recruited through the university subject pool. A series of a priori hypotheses were developed for each of the 6 interpersonal functioning scales of the MMPI-2-RF, expressed as predicted correlations with construct-relevant CAT-PD-SF scales...
September 23, 2016: Journal of Personality Assessment
https://www.readbyqxmd.com/read/27661139/mapping-the-mmpi-2-rf-substantive-scales-onto-internalizing-externalizing-and-thought-dysfunction-dimensions-in-a-forensic-inpatient-setting
#20
Isabella E Romero, Nasreen Toorabally, Danielle Burchett, Anthony M Tarescavage, David M Glassmire
Contemporary models of psychopathology-encompassing internalizing, externalizing, and thought dysfunction factors-have gained significant support. Although research indicates the Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF; Ben-Porath & Tellegen, 2008 /2011) measures these domains of psychopathology, this study addresses extant limitations in MMPI-2-RF diagnostic validity research by examining associations between all MMPI-2-RF substantive scales and broad dichotomous indicators of internalizing, externalizing, and thought dysfunction diagnoses in a sample of 1,110 forensic inpatients...
September 23, 2016: Journal of Personality Assessment
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