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https://www.readbyqxmd.com/read/29902049/a-distinct-configuration-of-mmpi-2-rf-scales-rcd-and-rc9-act-is-associated-with-suicide-attempt-risk-among-suicide-ideators-in-a-psychiatric-outpatient-sample
#1
Ian H Stanley, James R Yancey, Christopher J Patrick, Thomas E Joiner
Suicide is a major public health problem, claiming the lives of more than 40,000 individuals in the United States each year. Efforts are needed to (a) identify those at heightened risk for suicide, utilizing objective assessment methods and (b) determine factors that may be protective against engaging in suicidal behavior, even in the context of the desire to do so. Scales RCd (demoralization) and RC9 (hypomanic activation) of the Minnesota Multiphasic Personality Inventory (MMPI)-2 Restructured Form (MMPI-2-RF) may be valuable in this regard...
June 14, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29888947/risks-associated-with-overcontrolled-behavior-in-police-officer-recruits
#2
David M Corey, Martin Sellbom, Yossef S Ben-Porath
Potential externalizing tendencies have long been a focus of research in police candidates. Early studies often reported positive correlations between Minnesota Multiphasic Personality Inventory (MMPI) externalizing scales and problem behaviors in law enforcement officers. However, more recent investigations reveal mixed findings, with some showing either no significant correlations between externalizing measures and police performance problems or negative associations. In the current study, we examined associations between MMPI-2 Restructured Form (MMPI-2-RF) externalizing scale scores and personal history information (biodata) in a large sample (n = 1,226) of police officer candidates and observed expected positive correlations between them...
June 11, 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29865932/detection-of-symptom-over-reporting-on-the-neurobehavioral-symptom-inventory-in-oef-oif-ond-veterans-with-history-of-mild-tbi
#3
Anjuli S Bodapati, Hannah L Combs, Nicholas J Pastorek, Brian Miller, Maya Troyanskaya, Jennifer Romesser, Anita Sim, John Linck
OBJECTIVE: As part of routine care at Veterans Affairs facilities, veterans with a service-related traumatic brain injury (TBI) are administered a self-report post-concussive symptom measure, the Neurobehavioral Symptom Inventory (NSI). Interpreting the NSI can be problematic given that over-reporting on self-report measures is often found in both civilian and military patient populations. This study investigates embedded scales on the NSI that identify possible and probable symptom exaggeration...
June 5, 2018: Clinical Neuropsychologist
https://www.readbyqxmd.com/read/29850866/the-minnesota-multiphasic-personality-inventory-2-rf-in-treatment-seeking-veterans-with-history-of-mild-traumatic-brain-injury
#4
S M Jurick, L D Crocker, A V Keller, S N Hoffman, J Bomyea, M W Jacobson, A J Jak
Objective: This study examined the Minnesota Multiphasic Personality Inventory-Second Edition-Restructured Form (MMPI-2-RF) to better understand symptom presentation in a sample of treatment-seeking Operation Enduring Freedom/Operation Iraqi Freedom (OEF/OIF) Veterans with self-reported history of mild traumatic brain injury (mTBI). Method: Participants underwent a comprehensive clinical neuropsychological battery including performance and symptom validity measures and self-report measures of depressive, posttraumatic, and post-concussive symptomatology...
May 30, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29792532/the-moderating-influence-of-disorder-on-coached-overreporting-using-the-mmpi-2-rf
#5
Ariane M Olsen, Carlo O C Veltri
Overreporting has always been a concern within psychological evaluations. The Minnesota Multiphasic Personality Inventory-2-Restructured Form (Ben-Porath & Tellegen, 2008/2011 ) contains validity scales designed for detecting noncredible responses. In this study, 270 undergraduates were instructed to feign either schizophrenia, posttraumatic stress disorder (PTSD) or generalized anxiety disorder (GAD); some participants were coached on symptoms and validity scales. Results at both the individual protocol and mean validity scale score levels suggest that each feigned disorder moderates the effectiveness of coaching on validity scale detection...
May 24, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29787298/uses-and-misuses-of-ted-kaczynski-s-mmpi
#6
Yossef S Ben-Porath
Although case studies can be a helpful didactic aid when teaching personality assessment and illustrating use of a test, they can, of course, not be used as "evidence" that a test "works" or does not work. This article, however, reviews and discusses the far more problematic uses instantiated in a case study of Ted Kaczynski's Minnesota Multiphasic Personality Inventory (MMPI). A series of errors of omission and commission are identified in Butcher, Hass, Greene, and Nelson's ( 2015 ) effort to criticize the MMPI-2-RF...
May 22, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29777984/lc-ms-analysis-to-determine-the-biodistribution-of-a-polymer-coated-ilomastat-ocular-implant
#7
Abeer H A Mohamed-Ahmed, Alastair Lockwood, Hala Fadda, Shivam Madaan, Peng T Khaw, Steve Brocchini, Kersti Karu
Ilomastat is a matrix metalloproteinase inhibitor (MMPi) that has shown the potential to inhibit scarring (fibrosis) by mediating healing after injury or surgery. A long lasting ocular implantable pharmaceutical formulation of ilomastat is being developed to mediate the healing process to prevent scarring after glaucoma filtration surgery. The ilomastat implant was coated with water permeable and biocompatible phosphoryl choline polymer (PC1059) displayed extended slow release of ilomastat in vitro and in vivo...
May 16, 2018: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/29735645/matrix-metalloproteinase-inhibitors-in-cancer-therapy-turning-past-failures-into-future-successes
#8
REVIEW
Arthur Winer, Sylvia Adams, Paolo Mignatti
The matrix metalloproteinases (MMP) are a family of proteolytic enzymes that degrade multiple components of the extracellular matrix. A large body of experimental and clinical evidence has implicated MMPs in tumor invasion, neoangiogenesis, and metastasis, and therefore they represent ideal pharmacologic targets for cancer therapy. From the 1990s to early 2000s, synthetic inhibitors of MMPs (MMPI) were studied in various cancer types. Unexpectedly, despite strongly promising preclinical data, all trials were unsuccessful in reducing tumor burden or improving overall survival; in addition, MMPIs had unforeseen, severe side effects...
May 7, 2018: Molecular Cancer Therapeutics
https://www.readbyqxmd.com/read/29735610/reduction-in-secretion-of-very-low-density-lipoprotein-triacylglycerol-by-a-matrix-metalloproteinase-inhibitor-in-a-rat-model-of-diet-induced-hypertriglyceridemia
#9
Yoichi Kawashima, Yoshihiro Eguchi, Tohru Yamazaki, Minako Karahashi, Hiroshi Kawai, Naomi Kudo
Matrix metalloproteinase inhibitors (MMPIs) reduced serum triacylglycerol (TAG) levels in streptozotocin-induced diabetic rats and Zucker fa/fa rats in our previous study. However, the mechanisms underlying TAG reduction by MMPIs remain unclear. The present study aimed to elucidate the mechanism by which F81-1144b, a MMPI, lowers serum TAG levels in an animal model of high sucrose diet (HSD)-induced hypertriglyceridemia. F81-1144b was repeatedly administered to rats fed HSD, and its effects were evaluated on TAG levels in serum and the liver, very low density lipoprotein (VLDL) secretion, de novo fatty acid (FA) synthesis in the liver, and the expression of genes regulating the metabolism of FA, TAG, and VLDL in the liver and serum...
May 7, 2018: Journal of Pharmacology and Experimental Therapeutics
https://www.readbyqxmd.com/read/29704419/changes-in-ego-strength-in-patients-with-neurotic-and-personality-disorders-treated-with-a-short-term-comprehensive-psychodynamic-psychotherapy
#10
Katarzyna Cyranka, Krzysztof Rutkowski, Michał Mielimąka, Jerzy A Sobański, Katarzyna Klasa, Łukasz Müldner-Nieckowski, Edyta Dembińska, Bogna Smiatek-Mazgaj, Paweł Rodziński
OBJECTIVES: Analysis of changes in ego strength in the course of group psychotherapy in patients treated with neurotic and selected personality disorders (F40-F61, ICD-10). METHODS: 82 patients (61 women and 21 men) participated in the study. They underwent intensive short-term group psychotherapy treatment in a day hospital for neurotic and behavioural disorders. The assessment of the patients' personality functioning was carried out at the onset and the end of the psychotherapy...
February 28, 2018: Psychiatria Polska
https://www.readbyqxmd.com/read/29688185/-facebook-addiction
#11
Balázs Dávid, Attila Körmendi
Among behavioural addictions, addiction towards social media sites are identified, which are subtypes of compulsive internet usage. Among these, the most significant is the so-called Facebook addiction. Scientific experts agree, that this new phenomenon hasn't been known in detail yet, so it needs intensified scientific exploration. Different aspects of the personality are inclined to raise the probability of developing Facebook addiction. Neurotic and narcissistic traits of the personality are modifying the characteristic of Facebook use, and by this tendency, risk the individual for developing addiction...
2018: Psychiatria Hungarica: A Magyar Pszichiátriai Társaság Tudományos Folyóirata
https://www.readbyqxmd.com/read/29674965/development-of-matrix-metalloproteinase-2-inhibitors-for-cardioprotection
#12
Péter Bencsik, Krisztina Kupai, Anikó Görbe, Éva Kenyeres, Zoltán V Varga, János Pálóczi, Renáta Gáspár, László Kovács, Lutz Weber, Ferenc Takács, István Hajdú, Gabriella Fabó, Sándor Cseh, László Barna, Tamás Csont, Csaba Csonka, György Dormán, Péter Ferdinandy
The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and thiazole scaffolds and then tested in a screeening cascade for MMP inhibition. We found that the MMP-inhibiting effects of imidazole and thiazole carboxylic acid-based compounds are superior in efficacy in comparison to the conventional hydroxamic acid derivatives of the same molecules. Based on these results, a 568-membered focused library of imidazole and thiazole compounds was generated in silico and then the library members were docked to the 3D model of MMP-2 followed by an in vitro medium throughput screening (MTS) based on a fluorescent assay employing MMP-2 catalytic domain...
2018: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/29672106/mmpi-2-rf-characteristics-of-veterans-seeking-treatment-for-military-sexual-trauma
#13
Eliza S McManus, Lisa-Ann J Cuccurullo, Madeline Uddo, C Laurel Franklin
Military sexual trauma (MST) is defined as experiences of sexual assault or repeated, threatening, harassment during military service. MST events may not qualify within posttraumatic stress disorder (PTSD) Criterion A, making symptoms associated with MST unique from trauma-related disorders. Little research has been done to understand those presenting for MST treatment. Thus, this article provides Minnesota Multiphasic Personality Inventory 2-Restructured Form (MMPI-2-RF) scores of 33 U.S. veterans who experienced MST in an effort to better understand psychological and personality characteristics of this important and unique group of veterans...
April 2018: Psychological Assessment
https://www.readbyqxmd.com/read/29580567/association-of-depression-anxiety-and-post-traumatic-stress-disorder-with-migraine-data-from-kosovo
#14
Nexhmedin Shala, Shemsedin Dreshaj
INTRODUCTION: Migraine is ranked as the seventh leading cause of disability worldwide, and it is characterized by a manifestation of combined neurological, gastrointestinal, and autonomic symptoms linked with different provoking factors. AIM OF THE STUDY: This study investigates the association between migraine and PTSD, depression and anxiety in the Kosovo population during the post-war period. MATERIAL AND METHODS: 273 war survivors with headache were enrolled in the study and were divided into two groups: 153 individuals with confirmed migraine (the study group) and 120 individuals with non-migraine headaches (control group)...
March 15, 2018: Neurologia i Neurochirurgia Polska
https://www.readbyqxmd.com/read/29548501/the-expert-and-the-foreigner-reflections-of-forensic-transcultural-psychopathology-on-a-total-of-86-reports-by-experts-on-criminal-liability
#15
Isabella Merzagora, Alberto Amadasi, Alberto Blandino, Guido Travaini
In recent times Italy has been experiencing massive migration flows, therefore the attention on the issue of crimes committed by foreigners is increasing. But within trials, in the evaluation of criminal liability of foreigners, how do experts deal with them? Do the performed evaluations take cultural diversity into account? The present study took origin from these questions and examined a total of 86 reports by experts on criminal liability of foreign persons (16 females and 70 males). Examinees have been declared indictable in 31 cases (36%), totally mentally ill in 40 cases (45%) and with diminished liability in 15 cases (17%); when liability was excluded, examinees were diagnosed in 11 cases with mood disorders, in 23 cases with personality disorders, in 4 cases with adaptation disorders and post-traumatic stress disorder and in 10 cases with different diagnoses (in some cases more than one diagnosis was present)...
March 2018: International Journal of Law and Psychiatry
https://www.readbyqxmd.com/read/29480047/-low-intensity-evidence-based-cognitive-behavioural-therapy-of-a-patient-with-crohn-s-disease
#16
Dóra Antal-Uram, László Harsányi, Dóra Perczel-Forintos
Inflammatory bowel disease (Crohn's disease and colitis ulcerosa) is a chronic, long-term condition that causes chronic inflammation in the digestive tract, and shows an increasing incidence and prevalence worldwide. Changes in disease activity over time affect psychological distress which increases the risk of exacerbations. Beside somatic symptoms (such as abdominal pain, diarrhoea and weight loss), psychiatric comorbidity (in particular major depression, anxiety, social phobia) is common in patients with Crohn's disease...
March 2018: Orvosi Hetilap
https://www.readbyqxmd.com/read/29450796/prospective-comparison-of-the-minnesota-multiphasic-personality-inventory-2-mmpi-2-and-mmpi-2-restructured-form-mmpi-2-rf-in-predicting-treatment-outcomes-among-patients-with-chronic-low-back-pain
#17
Anthony M Tarescavage, Judith Scheman, Yossef S Ben-Porath
The purpose of the current study was to examine the relative utility of the most updated MMPI adult instrument, the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF), which was designed to address psychometric limitations of the MMPI-2. To this end, we compared mean scores and correlates of emotional distress treatment outcomes using the Depression Anxiety Stress Scales in a sample of 230 patients (73 males, 157 females) who had completed an interdisciplinary chronic pain rehabilitation program...
March 2018: Journal of Clinical Psychology in Medical Settings
https://www.readbyqxmd.com/read/29424554/predicting-postprobationary-job-performance-of-police-officers-using-cpi-and-mmpi-2-rf-test-data-obtained-during-preemployment-psychological-screening
#18
Ryan M Roberts, Anthony M Tarescavage, Yossef S Ben-Porath, Michael D Roberts
We examined associations between prehire California Psychological Inventory (CPI) and prorated Minnesota Multiphasic Personality Inventory-2 Restructured Form (MMPI-2-RF) scores (calculated from MMPI profiles) and supervisor ratings for a sample of 143 male police officers. Substantive scale scores in this sample were meaningfully lower than those obtained by the tests' normative samples in the case of the MMPI-2-RF and meaningfully higher in the case of the CPI (indicating less psychological dysfunction). Test scores from both instruments showed substantial range restriction, consistent with those produced by members of the police candidate comparison groups (Corey & Ben-Porath, 2014 ; Roberts & Johnson, 2001 )...
February 9, 2018: Journal of Personality Assessment
https://www.readbyqxmd.com/read/29400479/temperamental-workers-psychology-business-and-the-humm-wadsworth-temperament-scale-in-interwar-america
#19
Kira Lussier
This article traces the history of a popular interwar psychological test, the Humm-Wadsworth Temperament Scale (HWTS), from its development in the early 1930s to its adoption by corporate personnel departments. In popular articles, trade magazines, and academic journals, industrial psychologist Doncaster Humm and personnel manager Guy Wadsworth trumpeted their scale as a scientific measure of temperament that could ensure efficient hiring practices and harmonious labor relations by screening out "problem employees" and screening for temperamentally "normal" workers...
February 5, 2018: History of Psychology
https://www.readbyqxmd.com/read/29389175/comparability-of-structured-interview-of-reported-symptoms-sirs-and-structured-interview-of-reported-symptoms-second-edition-sirs-2-classifications-with-external-response-bias-criteria
#20
Jessica L Tylicki, Dustin B Wygant, Anthony M Tarescavage, Richard I Frederick, Elizabeth A Tyner, Robert P Granacher, Martin Sellbom
Rogers, Sewell, and Gillard (2010) released a revised version of the Structured Interview of Reported Symptoms (SIRS; Rogers, Bagby, & Dickens, 1992), the SIRS-2, which introduced several new scales, indices, and a new classification model with the overall goal of improving its classification of genuine versus feigned presentations. Since the release of the SIRS-2, several concerns have been raised regarding the quality of the SIRS-2 development and validation samples and the method used to calculate classification accuracy estimates...
February 1, 2018: Psychological Assessment
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