keyword
MENU ▼
Read by QxMD icon Read
search

Crocus sativus

keyword
https://www.readbyqxmd.com/read/27894973/is-there-nothing-new-under-the-sun-the-influence-of-herbals-and-pharmacopoeias-on-ethnobotanical-traditions-in-albacete-spain
#1
Diego Rivera, Alonso Verde, Concepción Obón, Francisco Alcaraz, Candelaria Moreno, Teresa Egea, José Fajardo, José Antonio Palazón, Arturo Valdés, Maria Adele Signorini, Piero Bruschi
ETHNOPHARMACOLOGICAL RELEVANCE: This paper has two overarching aims: (1) presenting the results of studying the Albacete tariff of medicines of 1526 and (2) broadly analyzing the origin and influences of medicinal traditional knowledge in the region of Albacete, Spain. We use historical and modern literature that may have influenced this knowledge. Our primary goal was to determine the ingredients used in the pharmacy in the 16th century CE in Albacete through the analysis of the tariff, and our secondary goal was to investigate until when ingredients and uses present in pharmacy and herbals persisted in later periods...
November 25, 2016: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/27890087/molecular-phylogeny-diversity-community-structure-and-plant-growth-promoting-properties-of-fungal-endophytes-associated-with-the-corms-of-saffron-plant-an-insight-into-the-microbiome-of-crocus-sativus-linn
#2
Zahoor Ahmed Wani, Dania Nazir Mirza, Palak Arora, Syed Riyaz-Ul-Hassan
A total of 294 fungal endophytes were isolated from the corms of Crocus sativus at two stages of crocus life cycle collected from 14 different saffron growing sites in Jammu and Kashmir (J & K) State, India. Molecular phylogeny assigned them into 36 distinct internal transcribed spacer (ITS) genotypes which spread over 19 genera. The diversity of endophytes was higher at the dormant than at the vegetative stage. The Saffron microbiome was dominated by Phialophora mustea and Cadophora malorum, both are dark septate endophytes (DSEs)...
December 2016: Fungal Biology
https://www.readbyqxmd.com/read/27878268/crocus-sativus-l-protects-against-sds%C3%A2-induced-intestinal-damage-and-extends-lifespan-in-drosophila-melanogaster
#3
Zonglin Liu, Yuchen Chen, Hong Zhang, Li Hua Jin
Medicinal plants are important sources of potentially therapeutic biochemical drugs. Crocus sativus L. has been used to treat various diseases in China, the Republic of Korea and Japan. The present study investigated the protective effect of C. sativus L. extract in Drosophila melanogaster intestinal immunity. Wild‑type flies were fed standard cornmeal‑yeast medium and used as controls, and flies supplemented with 1% C. sativus L. aqueous extract in standard medium were used as the experimental group...
November 15, 2016: Molecular Medicine Reports
https://www.readbyqxmd.com/read/27865556/trans-crocetin-improves-amyloid-%C3%AE-degradation-in-monocytes-from-alzheimer-s-disease-patients
#4
Roberto Tiribuzi, Lucia Crispoltoni, Valerio Chiurchiù, Antonella Casella, Celeste Montecchiani, Alberto Marco Del Pino, Mauro Maccarrone, Carlo Alberto Palmerini, Carlo Caltagirone, Toshitaka Kawarai, Aldo Orlacchio, Antonio Orlacchio
Herbal medicines have been recently employed in research and clinical studies for the potential treatment of behavioral and psychological symptoms associated with Alzheimer's Disease (AD) and other types of dementia. The present study investigates the effect of trans-crocetin, an active constituent of Crocus sativus L., to restore in vitro the reduced ability of AD patients' monocytes to degrade amyloid-β(1-42) (Aβ42). CD14(+) monocytes from 22 sporadic AD patients with moderate cognitive impairment were isolated; then, the role of trans-crocetin, purified from saffron extracts, was evaluated in terms of Aβ42 degradation rate through flow cytometry, as well as expression of cathepsin B by Western blotting...
November 6, 2016: Journal of the Neurological Sciences
https://www.readbyqxmd.com/read/27861946/saffron-a-promising-natural-medicine-in-the-treatment-of-metabolic-syndrome
#5
REVIEW
Bibi Marjan Razavi, Hossein Hosseinzadeh
Metabolic syndrome is a disorder which encompasses with obesity, high blood glucose, high cholesterol levels and high blood pressure. Moreover metabolic syndrome is considered as the most important risk factor for cardiovascular disease (CVD). CVD is the leading cause of mortality in the world for both men and women. Although several chemical drugs are available to treat metabolic risk factors, however, because of the safety, efficacy, cultural acceptability and lesser side effects, nowadays herbal therapy has a critical role in the treatment of these CVD risk factors...
November 12, 2016: Journal of the Science of Food and Agriculture
https://www.readbyqxmd.com/read/27861558/modulation-of-type-1-and-type-2-cannabinoid-receptors-by-saffron-in-a-rat-model-of-retinal-neurodegeneration
#6
Rita Maccarone, Cinzia Rapino, Darin Zerti, Monia di Tommaso, Natalia Battista, Stefano Di Marco, Silvia Bisti, Mauro Maccarrone
Experimental studies demonstrated that saffron (Crocus sativus) given as a dietary supplement counteracts the effects of bright continuous light (BCL) exposure in the albino rat retina, preserving both morphology and function and probably acting as a regulator of programmed cell death [1]. The purpose of this study was to ascertain whether the neuroprotective effect of saffron on rat retina exposed to BCL is associated with a modulation of the endocannabinoid system (ECS). To this aim, we used eight experimental groups of Sprague-Dawley rats, of which six were exposed to BCL for 24 hours...
2016: PloS One
https://www.readbyqxmd.com/read/27842483/patents-on-therapeutic-and-cosmetic-applications-of-bioactives-of-crocus-sativus-l-and-their-production-through-synthetic-biology-methods-a-review
#7
Mitali Nitin Dawalbhakta, Manasi Alok Telang
BACKGROUND: Saffron (Crocus sativus L.) has a long history of use as a food additive and a traditional medicine for treating a number of disorders. Prominent bioactives of saffron are crocin, crocetin and safranal. OBJECTIVE: The aim of this study was to carry out an extensive patent search to collect information on saffron bioactives and their derivatives as therapeutic and cosmeceutical agents. All patents related to the area of interest published globally till date have been reviewed...
November 14, 2016: Recent Patents on Biotechnology
https://www.readbyqxmd.com/read/27800651/crocin-attenuates-kindling-development-and-associated-cognitive-impairments-in-mice-via-inhibiting-reactive-oxygen-species-mediated-nf-%C3%AE%C2%BAb-activation
#8
Arindam Ghosh Mazumder, Pallavi Sharma, Vikram Patial, Damanpreet Singh
Crocin is a pharmacologically active carotenoid pigment mainly present in the stigmas of Crocus sativus L. (Iridaceae). It has been well explored in experimental animal models of cognitive impairments, depression, anxiety and epilepsy. The present study was designed to understand the effect of crocin on pentylenetetrazol (PTZ)-induced kindling development and its associated cognitive deficit in mouse. Crocin treatment at 5, 10 and 20 mg/kg p.o. doses showed marked reduction in severity of PTZ-induced seizures...
October 31, 2016: Basic & Clinical Pharmacology & Toxicology
https://www.readbyqxmd.com/read/27774904/medicinal-plants-for-the-treatment-of-asthma-a-traditional-persian-medicine-perspective
#9
Behjat Javadi, Amirhossein Sahebkar, Seyed Ahmad Emami
OBJECTIVE: To search major Traditional Persian Medicine (TPM) textbooks for medicinal plants used to treat asthma. The conformity of the TPM findings on the anti-asthmatic efficacy of plants with the findings of pharmacological studies was also explored. METHODS: Major TPM textbooks were hand searched to find medicinal plants used for the treatment of asthma. Scientific names of TPM-suggested plants were determined using botanical databases and were used for a multi-database electronic search in PubMed, Scopus, ScienceDirect and Google Scholar databases...
October 21, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27770798/protective-effects-of-saffron-extract-and-crocin-supplementation-on-fatty-liver-tissue-of-high-fat-diet-induced-obese-rats
#10
Maryam Mashmoul, Azrina Azlan, Norhafizah Mohtarrudin, Barakatun Nisak Mohd Yusof, Huzwah Khaza'ai, Hock Eng Khoo, Mehdi Farzadnia, Mohammad Taher Boroushaki
BACKGROUND: Saffron is the dried stigma of Crocus sativus L. flower which commonly used as a natural remedy to enhance health and even fights disease in the Middle-East and Southeast Asian countries. METHODS: This study was aimed to investigate protective effect of saffron extract and crocin in fatty liver tissue of high-fat diet induced obese rats. A total of 36 healthy male Sprague Dawley rats were divided into six groups. Two groups served as controls, a normal diet (ND) and a high-fat diet (HFD)...
October 22, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27769229/herbal-remedies-and-functional-foods-used-by-cancer-patients-attending-specialty-oncology-clinics-in-trinidad
#11
Yuri N Clement, Varune Mahase, Annelise Jagroop, Kelly Kissoon, Aarti Maharaj, Prashant Mathura, Chrys Mc Quan, Divya Ramadhin, Cherrista Mohammed
BACKGROUND: Cancer is a major disease worldwide, and many patients use complementary and alternative treatments. The purpose of this study was to identify the herbal remedies and functional foods used as complementary medicine by prostate, breast and colorectal cancer patients at speciality care facilities in Trinidad. We also sought to determine how patients rated the efficacy of these modalities compared with conventional treatment. METHODS: A descriptive, cross-sectional survey was conducted using an interviewer-administered pilot-tested de novo questionnaire during the period June to August 2012 at two speciality treatment centres on the island...
October 21, 2016: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/27765245/geographical-identification-of-saffron-crocus-sativus-l-by-linear-discriminant-analysis-applied-to-the-uv-visible-spectra-of-aqueous-extracts
#12
Angelo Antonio D'Archivio, Maria Anna Maggi
We attempted geographical classification of saffron using UV-visible spectroscopy, conventionally adopted for quality grading according to the ISO Normative 3632. We investigated 81 saffron samples produced in L'Aquila, Città della Pieve, Cascia, and Sardinia (Italy) and commercial products purchased in various supermarkets. Exploratory principal component analysis applied to the UV-vis spectra of saffron aqueous extracts revealed a clear differentiation of the samples belonging to different quality categories, but a poor separation according to the geographical origin of the spices...
March 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27701683/crocus-sativus-l-versus-citalopram-in-the-treatment-of-major-depressive-disorder-with-anxious-distress-a-double-blind-controlled-clinical-trial
#13
A Ghajar, S M Neishabouri, N Velayati, L Jahangard, N Matinnia, M Haghighi, A Ghaleiha, M Afarideh, S Salimi, A Meysamie, S Akhondzadeh
Introduction: Saffron (Crocus sativus L.) has demonstrated antidepressant effects in clinical studies and extensive anxiolytic effects in experimental animal models. Methods: 66 patients with major depressive disorder accompanied by anxious distress were randomly assigned to receive either saffron (30 mg/day) or citalopram (40 mg/day) for 6 weeks. Hamilton Rating Scale for Depression (HAM-D) and Hamilton Rating Scale for Anxiety (HAM-A) were used to assess treatment effect during the trial. Results: 60 participants finished the study...
October 4, 2016: Pharmacopsychiatry
https://www.readbyqxmd.com/read/27685092/comparative-metagenomics-reveal-phylum-level-temporal-and-spatial-changes-in-mycobiome-of-belowground-parts-of-crocus-sativus
#14
Sheetal Ambardar, Heikham Russiachand Singh, Malali Gowda, Jyoti Vakhlu
Plant-fungal associations have been explored by routine cultivation based approaches and cultivation based approaches cannot catalogue more than 5% of fungal diversity associated with any niche. In the present study, an attempt has been made to catalogue fungal diversity associated with belowground parts i.e. rhizosphere and cormosphere, of Crocus sativus (an economically important herb) during two growth stages, using cultivation independent ITS gene targeted approach, taking bulk soil as reference. The 454 pyrosequencing sequence data analysis suggests that the fungal diversity was niche and growth stage specific...
2016: PloS One
https://www.readbyqxmd.com/read/27681644/an-evidence-based-approach-to-medicinal-plants-for-the-treatment-of-sperm-abnormalities-in-traditional-persian-medicine
#15
REVIEW
M Tahvilzadeh, M Hajimahmoodi, T Toliyat, M Karimi, R Rahimi
Infertility is defined as inability of a sexually active couple to conceive after 1 year of regular intercourse without contraception. Male factors account for 20%-50% of cases of infertility. The aim of this study was to review medicinal plants that proposed to improve sperm abnormalities in traditional Persian medicine. For this purpose, PubMed, Scopus, GoogleScholar and Cochrane library were explored for medicinal plants used in traditional Persian medicine for sperm abnormalities to obtain studies giving any evidence for their efficacy and pharmacological mechanisms related to male infertility...
October 2016: Andrologia
https://www.readbyqxmd.com/read/27680892/crocin-protects-human-erythrocytes-from-nitrite-induced-methemoglobin-formation-and-oxidative-damage
#16
Fariheen Aisha Ansari, Shaikh Nisar Ali, Riaz Mahmood
Sodium nitrite (NaNO2 ) is a common contaminant of drinking water and food and feed chain. Nitrite induces oxidative damage in humans and animals. In this work, we studied the protective effect of crocin, the active constituent of Crocus sativus (saffron), on NaNO2 -induced oxidative damage in human erythrocytes. Changes in oxidative stress parameters following NaNO2 incubation of erythrocytes in presence and absence of crocin were determined. It was found that crocin pre-treatment significantly attenuated NaNO2 -induced oxidative damage of proteins, lipids, and plasma membrane...
September 28, 2016: Cell Biology International
https://www.readbyqxmd.com/read/27664653/sudan-dyes-in-adulterated-saffron-crocus-sativus-l-identification-and-quantification-by-1-h-nmr
#17
Eleftherios A Petrakis, Laura R Cagliani, Petros A Tarantilis, Moschos G Polissiou, Roberto Consonni
Saffron, the dried red stigmas of Crocus sativus L., is considered as one of the most expensive spices worldwide, and as such, it is prone to adulteration. This study introduces an NMR-based approach to identify and determine the adulteration of saffron with Sudan I-IV dyes. A complete (1)H and (13)C resonance assignment for Sudan I-IV, achieved by two-dimensional homonuclear and heteronuclear NMR experiments, is reported for the first time. Specific different proton signals for the identification of each Sudan dye in adulterated saffron can be utilised for quantitative (1)H NMR (qHNMR), a well-established method for quantitative analysis...
February 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27624387/tissue-engineered-regeneration-of-hemisected-spinal-cord-using-human-endometrial-stem-cells-poly-%C3%AE%C2%B5-caprolactone-scaffolds-and-crocin-as-a-neuroprotective-agent
#18
Panieh Terraf, Shideh Montasser Kouhsari, Jafar Ai, Hamideh Babaloo
Loss of motor and sensory function as a result of neuronal cell death and axonal degeneration are the hallmarks of spinal cord injury. To overcome the hurdles and achieve improved functional recovery multiple aspects, it must be taken into account. Tissue engineering approaches by coalescing biomaterials and stem cells offer a promising future for treating spinal cord injury. Here we investigated human endometrial stem cells (hEnSCs) as our cell source. Electrospun poly ε-caprolactone (PCL) scaffolds were used for hEnSC adhesion and growth...
September 13, 2016: Molecular Neurobiology
https://www.readbyqxmd.com/read/27610166/effects-of-saffron-crocus-sativus-l-stigma-extract-and-its-active-constituent-crocin-on-neuropathic-pain-responses-in-a-rat-model-of-chronic-constriction-injury
#19
Hossein Ali Safakhah, Tahereh Taghavi, Ali Rashidy-Pour, Abbas Ali Vafaei, Mina Sokhanvar, Narges Mohebbi, Mostafa Rezaei-Tavirani
This study was designed to investigate the therapeutic effects of saffron (Crocus sativus L.) and its main constituent crocin on neuropathic pain behavioral responses induced by chronic constriction injury (CCI) in rats. Adult male Wistar rats (200 to 250 g) were randomly assigned into 5 groups: Sham + saline, CCI + saline, CCI+ saffron (30 mg/kg), CCI + crocin (15 mg/kg) and CCI + crocin (30 mg/kg). CCI was induced by applying 4 loose ligatures around the sciatic nerve. Two weeks after nerve lesion, injections of saline, saffron or crocin were started and continued until 26(th) day post-surgery...
2016: Iranian Journal of Pharmaceutical Research: IJPR
https://www.readbyqxmd.com/read/27583656/efficacy-of-idiprost%C3%A2-gold-a-formulation-containing-serenoa-repens-crocus-sativus-and-pmbe-in-men-with-concomitant-luts-and-ed
#20
Giuseppe Quarto, Arturo Cola, Sisto Perdonà
BACKGROUND: The relationship between lower urinary tract symptoms (LUTS) and erectile dysfunction (ED) has received increased attention recently. This study aims to evaluate the efficacy of IDIProst® Gold, a product containing Serenoa repens, Crocus sativus and PMBE (Pinus massoniana bark extract), in improving sexual function, urinary symptoms and quality of life in patients with concomitant LUTS and ED. METHODS: 140 men (mean age 48 years) were enrolled and treated in this study...
September 1, 2016: Minerva Urologica e Nefrologica, the Italian Journal of Urology and Nephrology
keyword
keyword
56934
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"