Philippe Moingeon, Christiane Garbay, Muriel Dahan, Irène Fermont, Ali Benmakhlouf, Alain Gouyette, Pierre Poitou, Alain Saint-Pierre
Artificial intelligence and machine learning enable the construction of predictive models, which are currently used to assist in decision-making throughout the process of drug discovery and development. These computational models can be used to represent the heterogeneity of a disease, identify therapeutic targets, design and optimize drug candidates, and evaluate the efficacy of these drugs on virtual patients or digital twins. By combining detailed patient characteristics with the prediction of potential drug-candidate properties, artificial intelligence promotes the emergence of a "computational" precision medicine, allowing for more personalized treatments, better tailored to patient specificities with the aid of such predictive models...
April 2024: Médecine Sciences: M/S