keyword
MENU ▼
Read by QxMD icon Read
search

LFT

keyword
https://www.readbyqxmd.com/read/29321458/wax-assisted-one-step-enzyme-linked-immunosorbent-assay-on-lateral-flow-test-devices
#1
Masanori Ishii, Pattarachaya Preechakasedkit, Kentaro Yamada, Orawon Chailapakul, Koji Suzuki, Daniel Citterio
Lateral flow tests (LFTs) are widely used analytical tools characterized by portability, operator simplicity and short analysis times. A remaining challenge is their limited analytical sensitivity, which in classical immunoassay formats is overcome by enzyme-linked immunosorbent assay (ELISA) formats. The implementation of ELISA to an LFT format however, is hampered by the complexity of the procedure requiring the enzyme substrate addition after sample addition. In this work, a simple method for automation of this procedure without user interference is presented...
2018: Analytical Sciences: the International Journal of the Japan Society for Analytical Chemistry
https://www.readbyqxmd.com/read/29194774/current-clinical-algorithms-for-predicting-common-bile-duct-stones-have-only-moderate-accuracy
#2
Mohamed Ebrahim, Lars Tue Sorensen, Lars Nannestad Jorgensen, Evangelos Kalaitzakis
BACKGROUND & AIMS: A risk stratified approach for selecting patients likely to harbor common bile duct (CBD) stones to proceed directly to endoscopic or surgical stone clearance, rather than less invasive testing, has been proposed. We aimed to assess the performance of three clinical algorithms used to predict CBD stones. METHODS: All patients undergoing first-time ERCP in 2011-2012 due to suspected CBD stones were enrolled prospectively in a clinical database...
December 1, 2017: Digestive Endoscopy: Official Journal of the Japan Gastroenterological Endoscopy Society
https://www.readbyqxmd.com/read/29174520/liver-dysfunction-during-pregnancy-and-its-association-of-with-preterm-birth-in-china-a-prospective-cohort-study
#3
Xun Zhuang, Ai-Min Cui, Qin Wang, Xiao-Yan Cheng, Yi Shen, Wei-Hua Cai, Hai-Bo Li, Sheng Zhang, Gang Qin
BACKGROUND: Liver dysfunction is common in pregnancy but its association with adverse pregnancy outcomes such as preterm birth (PTB) remains unclear. METHODS: A prospective cohort of HBV-infected or uninfected pregnant women attending antenatal care was recruited at Nantong Maternal and Child Health Hospital between January 1, 2012, and June 30, 2016. Liver function tests (LFTs) were monitored through pregnancy. The primary outcomes were PTB and very PTB (delivery prior 37 and 32weeks' gestation respectively)...
November 21, 2017: EBioMedicine
https://www.readbyqxmd.com/read/29075564/gender-differences-in-safety-issues-during-fingolimod-therapy-evidence-from-a-real-life-relapsing-multiple-sclerosis-cohort
#4
Alessia Manni, Vita Direnzo, Antonio Iaffaldano, Valentina Di Lecce, Carla Tortorella, Stefano Zoccolella, Pietro Iaffaldano, Maria Trojano, Damiano Paolicelli
OBJECTIVE: Benefits and risks of new therapies in Multiple Sclerosis (MS) must be balanced carefully and tailored to patients. We aimed to describe our experience with Fingolimod (FTY), correlating demographics, clinical and hematological features of the Relapsing MS (RMS) cohort with the occurring Adverse Events (AEs). MATERIAL AND METHODS: Pretreatment screening tests, cardiological observation, and safety follow-up data were analyzed in 225 RMS patients. Changes in continuous data were analyzed post hoc with Wilcoxon ranks test; categorical variables were examined using McNemar test...
October 2017: Brain and Behavior
https://www.readbyqxmd.com/read/29075108/community-pharmacy-based-case-finding-for-copd-in-urban-and-rural-settings-is-feasible-and-effective
#5
Mariam Fathima, Bandana Saini, Juliet M Foster, Carol L Armour
BACKGROUND AND OBJECTIVE: Case finding of patients at risk of COPD by community pharmacists could identify a substantial number of people with undiagnosed COPD, but little is known about the feasibility and effectiveness of pharmacy-based COPD case finding using microspirometry. The objective of this study was to assess the feasibility and effectiveness of COPD case-finding service provided by community pharmacists, utilizing a combination of risk assessment questionnaire and microspirometry...
2017: International Journal of Chronic Obstructive Pulmonary Disease
https://www.readbyqxmd.com/read/29067150/care-standards-for-non-alcoholic-fatty-liver-disease-in-the-united-kingdom-2016-a-cross-sectional-survey
#6
David A Sheridan, Guru Aithal, William Alazawi, Michael Allison, Quentin Anstee, Jeremy Cobbold, Shahid Khan, Andrew Fowell, Stuart McPherson, Philip N Newsome, Jude Oben, Jeremy Tomlinson, Emmanouil Tsochatzis
OBJECTIVE: Guidelines for the assessment of non-alcoholic fatty liver disease (NAFLD) have been published in 2016 by National Institute for Health and Care Excellence and European Associations for the study of the Liver-European Association for the study of Diabetes-European Association for the study of Obesity. Prior to publication of these guidelines, we performed a cross-sectional survey of gastroenterologists and hepatologists regarding NAFLD diagnosis and management. DESIGN: An online survey was circulated to members of British Association for the Study of the Liver and British Society of Gastroenterology between February 2016 and May 2016...
October 2017: Frontline Gastroenterology
https://www.readbyqxmd.com/read/29065845/identification-of-electrophysiological-changes-in-alzheimer-s-disease-a-microarray-based-transcriptomics-and-molecular-pathway-analysis-study
#7
Zeenat Mirza, Nisreen Rajeh
Involvement of amyloid beta and tau proteins in pathogenesis of Alzheimer's disease (AD) has been studied extensively. However, electrophysiological activity, and cellular processes like membrane transport are mostly unstudied. Electrophysiological processes provide a bridge between brain activity and cognition, and show promise as translatable biomarkers in preclinical and clinical applications. Biochemical imbalance leads to change in glutamate-based neurotransmission, antioxidant capacity, and in membrane polarization-repolarization events, eventually, resulting in AD...
October 23, 2017: CNS & Neurological Disorders Drug Targets
https://www.readbyqxmd.com/read/28974877/pre-operative-hepatic-artery-resistive-index-is-a-non-invasive-predictive-indicator-of-prognosis-in-biliary-atresia
#8
Deepak Mittal, Veereshwar Bhatnagar, Sandeep Agarwala, Maddur Srinivas, Manisha Jana, Arun Kumar Gupta, Nibhriti Das, Manoj Kumar Singh
AIMS: The aim of this study is to evaluate hepatic artery resistive index (HARI) as a noninvasive prognostic predictor by correlating it with peripheral blood nitric oxide (NO) levels, portal pressure (PP) and histopathological changes in the liver in patients of biliary atresia (BA). MATERIALS AND METHODS: Twenty-five patients were included in the study prospectively from November 2012 to June 2014. All patients underwent Doppler sonography to calculate the HARI preoperatively...
October 2017: Journal of Indian Association of Pediatric Surgeons
https://www.readbyqxmd.com/read/28946570/effects-of-postural-exercises-in-patients-with-parkinson-s-disease-and-pisa-syndrome-a-pilot-study
#9
Francesco Lena, Ennio Iezzi, Mohammad Etoom, Marco Santilli, Diego Centonze, Calogero Foti, Giovanni Grillea, Nicola Modugno
BACKGROUND: Pisa syndrome (PS) or lateral axial dystonia is often seen in patients with Parkinson's disease (PD). It is characterized by a marked and reversible lateral flexion of the trunk (LFT) more than 10°. OBJECTIVE: To assess the effectiveness of a program of postural exercises and assess the effectiveness in term of pattern of muscular hyperactivity. METHODS: A total of 6 patients with PD and PS enrolled in the program of 10 sessions of postural exercise (90 min/session)...
2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28940587/liver-dysfunction-in-chronic-lymphocytic-leukemia-prevalence-outcomes-and-pathological-findings
#10
Paul J Hampel, Kari G Chaffee, Rebecca L King, Douglas Simonetto, Melissa C Larson, Sara Achenbach, Timothy G Call, Wei Ding, Saad S Kenderian, Jose F Leis, Asher A Chanan-Khan, Deborah A Bowen, Michael J Conte, Susan M Schwager, Curtis A Hanson, Susan L Slager, Neil E Kay, Tait D Shanafelt, Sameer A Parikh
The prevalence of liver dysfunction and its association with outcomes in patients with previously untreated chronic lymphocytic leukemia (CLL) is unknown. Newly diagnosed (<12 months) previously untreated CLL patients seen at Mayo Clinic, Rochester, MN between 9/1993 and 4/2016 who had baseline assessment of at least one liver function test (LFT) were included in this analysis. The prevalence of liver dysfunction at baseline, proportion of patients who acquired LFT abnormalities, time to first therapy (TTFT) and overall survival (OS) were assessed...
September 22, 2017: American Journal of Hematology
https://www.readbyqxmd.com/read/28932906/safety-study-and-therapeutic-drug-monitoring-of-the-oral-tablet-formulation-of-posaconazole-in-patients-with-haematological-malignancies
#11
C Boglione-Kerrien, S Picard, C Tron, S Nimubona, J-P Gangneux, S Lalanne, F Lemaitre, E Bellissant, M-C Verdier, A Petitcollin
PURPOSE: Posaconazole is a triazole antifungal widely used for prophylaxis of invasive fungal disease (IFI). Posaconazole tablets allow reaching higher plasma levels than the oral suspension, but safety data with this formulation in real life are scarce. This study aimed at evaluating the safety profile, the pharmacokinetic variability, and the concentration-toxicity relationship of posaconazole tablets in patients with haematological malignancies. METHODS: Sixty neutropenic patients treated with posaconazole tablets for prophylaxis of IFI were prospectively included in the study...
September 20, 2017: Journal of Cancer Research and Clinical Oncology
https://www.readbyqxmd.com/read/28912916/acute-liver-failure-in-a-patient-travelling-from-asia-the-other-face-of-the-coin-of-infectious-disease
#12
Balen Abdulrahman, Mohamed H Ahmed, John Ramage
We present a case of a 63-year-old male who had travelled from South India to United Kingdom (UK) visiting relatives. He had developed episodes of diarrhea, vomiting and fevers while travelling and on assessment in hospital, mild abdominal distension was noted with rapid deterioration to hypovolemic shock. Initial blood test showed a low platelet count with deranged liver function tests (LFTs). It was noted that during admission to intensive care unit (ICU), blood continued to ooze from a previous surgical laparoscopy wound, central and arterial line access sites...
August 2017: Gastroenterology Research
https://www.readbyqxmd.com/read/28873351/frequency-and-pathological-characteristics-of-drug-induced-liver-injury-in-a-tertiary-medical-center
#13
Mark Ettel, Gabriel Acosta Gonzalez, Shweta Gera, Ogechukwu Eze, Samuel Sigal, James S Park, Ruliang Xu
Drug-induced liver injury (DILI) accounts for approximately 10% of acute hepatitis cases. DILI can arise as idiosyncratic or intrinsic injury from hundreds of drugs, herbals, and nutritional supplements and is essential to recognize as one of the differential diagnoses of hepatitis in a liver biopsy. The purpose of this study is to investigate the frequency and pathological characteristics of DILI related to the variety of hepatotoxic agents. We searched our pathology database for all patients with hepatitis diagnosed on liver biopsy from January 2012 to May 2016, and selected patients with a diagnosis of DILI...
September 2, 2017: Human Pathology
https://www.readbyqxmd.com/read/28821350/frequency-and-prognostic-significance-of-abnormal-liver-function-tests-in-patients-with-cardiogenic-shock
#14
MULTICENTER STUDY
Toni Jäntti, Tuukka Tarvasmäki, Veli-Pekka Harjola, John Parissis, Kari Pulkki, Alessandro Sionis, Jose Silva-Cardoso, Lars Køber, Marek Banaszewski, Jindrich Spinar, Valentin Fuhrmann, Jukka Tolonen, Valentina Carubelli, Salvatore diSomma, Alexandre Mebazaa, Johan Lassus
Cardiogenic shock (CS) is a cardiac emergency often leading to multiple organ failure and death. Assessing organ dysfunction and appropriate risk stratification are central for the optimal management of these patients. The purpose of this study was to assess the prevalence of abnormal liver function tests (LFTs), as well as early changes of LFTs and their impact on outcome in CS. We measured LFTs in 178 patients in CS from serial blood samples taken at 0 hours, 12 hours, and 24 hours. The associations of LFT abnormalities and their early changes with all-cause 90-day mortality were estimated using Fisher's exact test and Cox proportional hazards regression analysis...
October 1, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/28806303/does-a-combination-of-laparoscopic-approach-and-full-fast-track-multimodal-management-decrease-postoperative-morbidity-a-multicenter-randomized-controlled-trial
#15
RANDOMIZED CONTROLLED TRIAL
Léon Maggiori, Eric Rullier, Jérémie H Lefevre, Jean-Marc Régimbeau, Stéphane Berdah, Mehdi Karoui, Jérome Loriau, Arnaud Alvès, Eric Vicaut, Yves Panis
OBJECTIVE: The aim of this study was to assess whether association of laparoscopic approach and full fast track multimodal (FFT) management can reduce postoperative morbidity after colorectal cancer surgery, as compared to laparoscopic approach with limited fast-track program (LFT). SUMMARY OF BACKGROUND DATA: Recent advances in colorectal cancer surgery are introduction of laparoscopy and FFT implementation. METHODS: Patients eligible for elective laparoscopic colorectal cancer surgery were randomized into 2 groups: FFT or LFT care (with only early oral intake and mobilization starting on Day 1)...
November 2017: Annals of Surgery
https://www.readbyqxmd.com/read/28792163/auramine-o-synthetic-yellow-cow-dung-powder-poisoning-rare-but-fatal
#16
Shubhangi Dhadke, Vitthal Dhadke, Abhijit Giram
INTRODUCTION: Cow dung known since long ago for its germicidal properties, used by Indian villagers to clean the house premises. As cow dung is not available easily, nowadays people have started using synthetic yellow coloured powder (Auramine-o) available easily in grocery shops locally known as "Morechap powder" in districts of Maharashtra. As the poisoning is rare, very few literatures are available mentioning the detailed mechanism of action, clinical presentation and complications...
July 2017: Journal of the Association of Physicians of India
https://www.readbyqxmd.com/read/28571204/impact-of-biliary-calculi-on-the-liver
#17
Raju Rangaswamy, Chabungbam Gyan Singh, Haobam Manihar Singh, P Punyabati, Kuotho T Nyuwi
INTRODUCTION: Gallstone is implicated for hepatocellular injury due to chronic extra hepatic large bile duct obstruction with or without repeated episodes of cholangitis. AIM: To study the liver changes in patients undergoing operative procedure for gallstone disease and to determine the relationship between severity of these changes with position of biliary calculus in biliary tree. MATERIALS AND METHODS: Sixty patients who underwent operative procedure for gallstone disease between October 2013 and September 2015 were evaluated...
April 2017: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28542246/a-drastic-superoxide-dependent-oxidative-stress-is-prerequisite-for-the-down-regulation-of-irp1-insights-from-studies-on-sod1-deficient-mice-and-macrophages-treated-with-paraquat
#18
Anna Milczarek, Rafał R Starzyński, Agnieszka Styś, Aneta Jończy, Robert Staroń, Agnieszka Grzelak, Paweł Lipiński
Iron regulatory protein 1 (IRP1) is a cytosolic bifunctional [4Fe-4S] protein which exhibits aconitase activity or binds iron responsive elements (IREs) in untranslated regions of specific mRNA encoding proteins involved in cellular iron metabolism. Superoxide radical (O2.-) converts IRP1 from a [4Fe-4S] aconitase to a [3Fe-4S] "null" form possessing neither aconitase nor trans-regulatory activity. Genetic ablation of superoxide dismutase 1 (SOD1), an antioxidant enzyme that acts to reduce O2.- concentration, revealed a new O2...
2017: PloS One
https://www.readbyqxmd.com/read/28524363/donor-transmitted-mutation-of-the-abcb11-gene-and-ensuing-intrahepatic-cholestasis-of-pregnancy-in-a-liver-transplant-recipient
#19
LETTER
Tiong Yeng Lim, Iona Coltart, Pierre Foskett, Richard Thompson, Sandra Strautnieks, Leonie Penna, Catherine Williamson, Rosa Miquel, Michael A Heneghan
No abstract text is available yet for this article.
September 2017: Liver Transplantation
https://www.readbyqxmd.com/read/28512557/increased-vasoocclusive-crises-in-o-blood-group-sickle-cell-disease-patients-association-with-underlying-thrombospondin-levels
#20
M Al Huneini, S Alkindi, V Panjwani, K Al Falahi, B Al Balushi, D Gravell, C H Ho, R Krishnamoorthy, A V Pathare
OBJECTIVES: To explore the incidence of vaso-occlusive crisis (VOC) in Blood Group "O" sickle cell disease (SCD) patients, and correlate it with the blood group and thrombospondin (TSP) levels. METHODS: In 89 consecutive SCD patients, blood samples were obtained for von Williebrand factor (vWF:Ag) antigen, collagen binding activity (CBA), ristocetin binding activity (RCo), blood group typing, C-reactive protein (CRP), high performance liquid chromatography (HPLC), Serum TSP 1 and TSP 2 levels, complete blood counts (CBC), lactic dehydrogenase (LDH) levels, liver function (LFT) and renal function tests (RFT) during VOC episodes and in steady state conditions...
2017: Mediterranean Journal of Hematology and Infectious Diseases
keyword
keyword
56918
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"