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https://www.readbyqxmd.com/read/29655946/big-data-handling-mechanisms-in-the-healthcare-applications-a-comprehensive-and-systematic-literature-review
#1
REVIEW
Asma Pashazadeh, Nima Jafari Navimipour
Healthcare provides many services such as diagnosing, treatment, prevention of diseases, illnesses, injuries, and other physical and mental disorders. Large-scale distributed data processing applications in healthcare as a basic concept operates on large amounts of data. Therefore, big data application functions are the main part of healthcare operations, but there was not any comprehensive and systematic survey about studying and evaluating the important techniques in this field. Therefore, this paper aims at providing the comprehensive, detailed, and systematic study of the state-of-the-art mechanisms in the big data related to healthcare applications in five categories, including machine learning, cloud-based, heuristic-based, agent-based, and hybrid mechanisms...
April 12, 2018: Journal of Biomedical Informatics
https://www.readbyqxmd.com/read/29655594/no-effect-of-prenatal-vitamin-d-deficiency-on-autism-relevant-behaviours-in-multiple-inbred-strains-of-mice
#2
M Langguth, M Fassin, S Alexander, K M Turner, T H J Burne
Autism Spectrum Disorders (ASD) is a group of neurodevelopmental disorders commonly characterised by verbal and non-verbal communication deficits, impaired social interaction and repetitive, stereotypic behaviours. The aetiology of ASD is most likely a combination of genetic and environmental factors. Epidemiological evidence suggests that prenatal vitamin D deficiency is associated with an increased incidence of ASD. The overall aim of this study was to investigate prenatal vitamin D deficiency on ASD-related behavioural phenotypes in multiple inbred strains of mice...
April 12, 2018: Behavioural Brain Research
https://www.readbyqxmd.com/read/29652955/-neurodevelopmental-assessment-of-patients-with-congenital-hypothyroidism
#3
Alicia Núñez, Paula Bedregal, Carlos Becerra, Francisca Grob L
Congenital hypothyroidism (CH) is the most common cause of preventable cognitive disability worldwide. Generally, it is produced by an alteration in the embryogenesis of the thyroid gland or by an alteration in the synthesis of thyroid hormones, which determine that affected patients have low or absent thyroid hormone concentrations. The importance of this fact is that brain development during the first three years of life is highly dependent on thyroid hormones. Prior to the implementation of national neonatal screening programs around the world, 8 to 27% of children with CH had an IQ lower than 70...
December 2017: Revista Médica de Chile
https://www.readbyqxmd.com/read/29651830/qualitative-and-quantitative-revaluation-of-specific-learning-disabilities-a-multicentric-study
#4
Francesca F Operto, Roberta Mazza, Maura Buttiglione, Francesco Craig, Alessandro Frolli, Simone Pisano, Lucia Margari, Giangennaro Coppola
BACKGROUND: Specific learning disabilities are disorders that affect the instrumental skills of academic learning, leaving intact the general intellectual functioning. It is possible to distinguish: dyslexia, dysorthography, dysgraphia, and dyscalculia. The diagnosis is made according to DSMV. The aim of this study is to evaluate the implementation of Law N° 170 following a diagnosis of specific learning disabilities in children and their evolution over time. METHODS: The sample under examination consists of 75 children, 56 males and 18 females aged 7,8 to 16 years, with a diagnosis of specific learning disabilities; a revaluation was carried outthrough the use of standardized instruments according to age and school attended...
April 12, 2018: Minerva Pediatrica
https://www.readbyqxmd.com/read/29651365/mastication-evaluation-with-unsupervised-learning-using-an-inertial-sensor-based-system
#5
Caroline Vieira Lucena, Marcelo Lacerda, Rafael Caldas, Fernando Buarque De Lima Neto, Diego Rativa
There is a direct relationship between the prevalence of musculoskeletal disorders of the temporomandibular joint and orofacial disorders. A well-elaborated analysis of the jaw movements provides relevant information for healthcare professionals to conclude their diagnosis. Different approaches have been explored to track jaw movements such that the mastication analysis is getting less subjective; however, all methods are still highly subjective, and the quality of the assessments depends much on the experience of the health professional...
2018: IEEE Journal of Translational Engineering in Health and Medicine
https://www.readbyqxmd.com/read/29651237/dpp6-loss-impacts-hippocampal-synaptic-development-and-induces-behavioral-impairments-in-recognition-learning-and-memory
#6
Lin Lin, Jonathan G Murphy, Rose-Marie Karlsson, Ronald S Petralia, Jakob J Gutzmann, Daniel Abebe, Ya-Xian Wang, Heather A Cameron, Dax A Hoffman
DPP6 is well known as an auxiliary subunit of Kv4-containing, A-type K+ channels which regulate dendritic excitability in hippocampal CA1 pyramidal neurons. We have recently reported, however, a novel role for DPP6 in regulating dendritic filopodia formation and stability, affecting synaptic development and function. These results are notable considering recent clinical findings associating DPP6 with neurodevelopmental and intellectual disorders. Here we assessed the behavioral consequences of DPP6 loss. We found that DPP6 knockout (DPP6-KO) mice are impaired in hippocampus-dependent learning and memory...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29649977/development-of-fine-motor-skills-is-associated-with-expressive-language-outcomes-in-infants-at-high-and-low-risk-for-autism-spectrum-disorder
#7
Boin Choi, Kathryn A Leech, Helen Tager-Flusberg, Charles A Nelson
BACKGROUND: A growing body of research suggests that fine motor abilities are associated with skills in a variety of domains in both typical and atypical development. In this study, we investigated developmental trajectories of fine motor skills between 6 and 24 months in relation to expressive language outcomes at 36 months in infants at high and low familial risk for autism spectrum disorder (ASD). METHODS: Participants included 71 high-risk infants without ASD diagnoses, 30 high-risk infants later diagnosed with ASD, and 69 low-risk infants without ASD diagnoses...
April 12, 2018: Journal of Neurodevelopmental Disorders
https://www.readbyqxmd.com/read/29649712/sexual-abuse-but-not-posttraumatic-stress-disorder-is-associated-with-neurocognitive-deficits-in-south-african-traumatized-adolescents
#8
Sarah V Biedermann, Stefanie Meliss, Candice Simmons, Jani Nöthling, Sharain Suliman, Soraya Seedat
OBJECTIVES: Neurocognitive impairments are commonly observed in adults suffering from posttraumatic stress disorder (PTSD). The picture is less clear in adolescents. Childhood sexual abuse (CSA) may have an independent influence on neuropsychological test performance and provide partial explanatory power of the inconsistent findings. We hypothesized that adolescents with PTSD who have also suffered sexual abuse would have most pronounced deficits on neurocognitive testing. METHODS: In a cross-sectional design, 105 traumatized South African adolescents, of whom 52 fulfilled criteria of PTSD and 34 reported CSA, were studied...
April 9, 2018: Child Abuse & Neglect
https://www.readbyqxmd.com/read/29649513/neurofeedback-control-of-the-human-gabaergic-system-using-non-invasive-brain-stimulation
#9
Satoko Koganemaru, Yusuke Mikami, Hitoshi Maezawa, Satoshi Ikeda, Katsunori Ikoma, Tatsuya Mima
Neurofeedback has been a powerful method for self-regulating brain activities to elicit potential ability of human mind. GABA is a major inhibitory neurotransmitter in the central nervous system. Transcranial magnetic stimulation (TMS) is a tool that can evaluate the GABAergic system within the primary motor cortex (M1) using paired-pulse stimuli, short intracortical inhibition (SICI). Herein we investigated whether neurofeedback learning using SICI enabled us to control the GABAergic system within the M1 area...
April 9, 2018: Neuroscience
https://www.readbyqxmd.com/read/29649023/helping-a-child-with-autism-spectrum-disorder-cope-with-divorce
#10
Marie Reilly, Jason Fogler, Carolyn Bridgemohan, Melora Wiley, Carol Weitzman, Marilyn Augustyn
Aaron is an 11-year-old boy with autism spectrum disorder (ASD), with cognitive and language skills in the above-average range, whose parents have recently separated. Aaron's mother initiated the separation when she learned that Aaron's father had maintained a relationship with a woman with whom he has a 10-year-old daughter. When Aaron's mother discovered this relationship, she demanded that Aaron's father leave their home.Aaron's father has moved in with his long-term girlfriend and keeps in contact with Aaron by calling once a day...
April 10, 2018: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/29645066/intellectual-performance-of-children-of-mothers-with-an-untreated-thyroid-disorder-in-the-first-pregnancy-trimester
#11
Irena Komendová, Sylvie Špitálníková
INTRODUCTION: The focus of the present study was the importance of the mother's thyroid function for foetal development in the first trimester, when the baby is totally dependent on the mother for thyroid hormones. MATERIAL AND METHODS: The study consisted in testing the intellectual performance of children with both euthyroid and thyroid-dysfunction mothers. The experimental group comprised 60 children of mothers with an untreated thyroid disorder in the first trimester of their pregnancy (TSH≥3...
April 12, 2018: Endokrynologia Polska
https://www.readbyqxmd.com/read/29644212/pigmentary-disorders-and-their-management-analyzing-current-evidence-conference-proceedings-and-learning-points-pigmentarycon-2017-november-10-12-indore-india
#12
Indrashis Podder, Anupam Das, Rashmi Sarkar
No abstract text is available yet for this article.
March 2018: Indian Dermatology Online Journal
https://www.readbyqxmd.com/read/29643822/working-memory-and-reinforcement-schedule-jointly-determine-reinforcement-learning-in-children-potential-implications-for-behavioral-parent-training
#13
Elien Segers, Tom Beckers, Hilde Geurts, Laurence Claes, Marina Danckaerts, Saskia van der Oord
Introduction: Behavioral Parent Training (BPT) is often provided for childhood psychiatric disorders. These disorders have been shown to be associated with working memory impairments. BPT is based on operant learning principles, yet how operant principles shape behavior (through the partial reinforcement (PRF) extinction effect, i.e., greater resistance to extinction that is created when behavior is reinforced partially rather than continuously) and the potential role of working memory therein is scarcely studied in children...
2018: Frontiers in Psychology
https://www.readbyqxmd.com/read/29643355/reverse-translated-and-gold-standard-continuous-performance-tests-predict-global-cognitive-performance-in-schizophrenia
#14
Andrew W Bismark, Michael L Thomas, Melissa Tarasenko, Alexandra L Shiluk, Sonia Y Rackelmann, Jared W Young, Gregory A Light
Attentional dysfunction contributes to functional impairments in schizophrenia (SZ). Sustained attention is typically assessed via continuous performance tasks (CPTs), though many CPTs have limited cross-species translational validity and place demands on additional cognitive domains. A reverse-translated 5-Choice Continuous Performance Task (5C-CPT) for human testing-originally developed for use in rodents-was designed to minimize demands on perceptual, visual learning, processing speed, or working memory functions...
April 12, 2018: Translational Psychiatry
https://www.readbyqxmd.com/read/29642973/enhancing-health-literacy-through-co-design-development-of-culturally-appropriate-materials-on-genetic-risk-and-customary-consanguineous-marriage
#15
Parveen Azam Ali, Sarah Salway, Elizabeth Such, Andrew Dearden, Matt Willox
AimTo develop a simple health literacy intervention aimed at supporting informed reproductive choice among members of UK communities practising customary consanguineous marriage. BACKGROUND: The contribution of 'health literacy' to reducing health inequalities and improving primary health-care efficiency is increasingly recognised. Enhancing genetic literacy has received particular attention recently. Consanguineous marriage is customarily practised among some UK minority ethnic communities and carries some increased risk of recessive genetic disorders among offspring compared with unions among unrelated partners...
April 12, 2018: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/29642715/effects-of-dynamic-text-in-an-aac-app-on-sight-word-reading-for-individuals-with-autism-spectrum-disorder
#16
Jessica Caron, Janice Light, Christine Holyfield, David McNaughton
The purpose of this study was to investigate the effects of Transition to Literacy (T2L) software features (i.e., dynamic text and speech output upon selection of a graphic symbol) within a grid display in an augmentative and alternative communication (AAC) app, on the sight word reading skills of individuals with autism spectrum disorders (ASD) and complex communication needs. The study implemented a single-subject multiple probe research design across one set of three participants. The same design was utilized with an additional set of two participants...
April 12, 2018: Augmentative and Alternative Communication: AAC
https://www.readbyqxmd.com/read/29642656/socio-economic-disparities-and-difficulties-to-access-to-healthcare-services-among-canadian-children-with-neurodevelopmental-disorders-and-disabilities
#17
Sana Raouafi, Sofiane Achiche, Maxime Raison
Objectives: The aim of this study is to identify the association between levels of severity of nurodevelopmental disorders and disabilities (NDD/D) in children, their household socio-economic status (SES), and the frequency of visits to a healthcare provider; and (2) to examine how the severity of disability differs with these determinants among NDD/D subgroups, to make a social policy change and improve access to health care system. Methods: The data from the 2006 Participation and Activity Limitation Survey (PALS) on children (5-14y), collected by Statistics Canada, was analyzed (n= 7,072 and weighted n = 340,340)...
March 29, 2018: Epidemiology and Health
https://www.readbyqxmd.com/read/29629788/statewide-implementation-of-an-evidence-based-trauma-intervention-in-schools
#18
Sharon A Hoover, Heather Sapere, Jason M Lang, Erum Nadeem, Kristin L Dean, Pamela Vona
The goal of the current article is to describe the implementation and outcomes of an innovative statewide dissemination approach of the evidence-based trauma intervention Cognitive Behavioral Intervention for Trauma in Schools (CBITS). In the context of a 2-year statewide learning collaborative effort, 73 CBITS groups led by 20 clinicians from 5 different school-based mental health provider organizations served a total of 350 racially and ethnically diverse (66.9% Hispanic, 26.2% Black/African American, 43...
March 2018: School Psychology Quarterly
https://www.readbyqxmd.com/read/29628935/neurodevelopmental-genetic-diseases-associated-with-microdeletions-and-microduplications-of-chromosome-17p13-3
#19
REVIEW
Sara M Blazejewski, Sarah A Bennison, Trevor H Smith, Kazuhito Toyo-Oka
Chromosome 17p13.3 is a region of genomic instability that is linked to different rare neurodevelopmental genetic diseases, depending on whether a deletion or duplication of the region has occurred. Chromosome microdeletions within 17p13.3 can result in either isolated lissencephaly sequence (ILS) or Miller-Dieker syndrome (MDS). Both conditions are associated with a smooth cerebral cortex, or lissencephaly, which leads to developmental delay, intellectual disability, and seizures. However, patients with MDS have larger deletions than patients with ILS, resulting in additional symptoms such as poor muscle tone, congenital anomalies, abnormal spasticity, and craniofacial dysmorphisms...
2018: Frontiers in Genetics
https://www.readbyqxmd.com/read/29628620/automatic-analysis-of-pronunciations-for-children-with-speech-sound-disorders
#20
Shiran Dudy, Steven Bedrick, Meysam Asgari, Alexander Kain
Computer-Assisted Pronunciation Training (CAPT) systems aim to help a child learn the correct pronunciations of words. However, while there are many online commercial CAPT apps, there is no consensus among Speech Language Therapists (SLPs) or non-professionals about which CAPT systems, if any, work well. The prevailing assumption is that practicing with such programs is less reliable and thus does not provide the feedback necessary to allow children to improve their performance. The most common method for assessing pronunciation performance is the Goodness of Pronunciation (GOP) technique...
July 2018: Computer Speech & Language
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