keyword
MENU ▼
Read by QxMD icon Read
search

Bias modification

keyword
https://www.readbyqxmd.com/read/29453799/impact-of-post-diagnostic-statin-use-on-ovarian-cancer-mortality-a-systematic-review-and-meta-analysis-of-observational-studies
#1
Xia Li, Jing Zhou
AIM: To comprehensively evaluate the association between post-diagnostic statin use and mortality of ovarian cancer (OC) patients. METHODS: Using a comprehensive strategy, multiple databases (Medline, Embase, and Web of Science) were systematically searched to identify observational studies that examined the correlation between statin use and OC mortality up to December 31, 2017. The studies were independently reviewed and selected based on predetermined selection criteria...
February 17, 2018: British Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/29452395/mini-extracorporeal-circulation-technology-conventional-bypass-and-prime-displacement-in-isolated-coronary-and-aortic-valve-surgery-a-propensity-matched-in-hospital-and-survival-analysis
#2
Priyadharshanan Ariyaratnam, Lindsay A Mclean, Alexander Cale, Mubarak A Chaudhry, Ajith Vijayan, Neil Richards, Martin A Jarvis, Yama Haqzad, Dumbor Ngaage, Michael E Cowen, Mahmoud Loubani
OBJECTIVES: Conventional cardiopulmonary bypass is the most commonly used means of artificial circulation in cardiac surgery. However, it suffers from the effects of haemodilution and activation of inflammatory/coagulation cascades. Prime displacement (PD) can offset haemodilution and Mini-Extracorporeal Technology (MIECT) can offset both. So far, no study has compared all of these modalities together; hence, we compared the outcomes of these 3 modalities at our institution. METHODS: This was a retrospective analysis of our cardiac surgical database...
February 14, 2018: Interactive Cardiovascular and Thoracic Surgery
https://www.readbyqxmd.com/read/29449456/place-learning-overrides-innate-behaviors-in-drosophila
#3
Vincent Baggett, Aditi Mishra, Abigail L Kehrer, Abbey O Robinson, Paul Shaw, Troy Zars
Animals in a natural environment confront many sensory cues. Some of these cues bias behavioral decisions independent of experience, and action selection can reveal a stimulus-response (S-R) connection. However, in a changing environment it would be a benefit for an animal to update behavioral action selection based on experience, and learning might modify even strong S-R relationships. How animals use learning to modify S-R relationships is a largely open question. Three sensory stimuli, air, light, and gravity sources were presented to individual Drosophila melanogaster in both naïve and place conditioning situations...
March 2018: Learning & Memory
https://www.readbyqxmd.com/read/29448335/zealots-in-the-mean-field-noisy-voter-model
#4
Nagi Khalil, Maxi San Miguel, Raul Toral
The influence of zealots on the noisy voter model is studied theoretically and numerically at the mean-field level. The noisy voter model is a modification of the voter model that includes a second mechanism for transitions between states: Apart from the original herding processes, voters may change their states because of an intrinsic noisy-in-origin source. By increasing the importance of the noise with respect to the herding, the system exhibits a finite-size phase transition from a quasiconsensus state, where most of the voters share the same opinion, to one with coexistence...
January 2018: Physical Review. E
https://www.readbyqxmd.com/read/29447217/does-napping-enhance-the-effects-of-cognitive-bias-modification-appraisal-training-an-experimental-study
#5
Marcella L Woud, Jan C Cwik, Simon E Blackwell, Birgit Kleim, Emily A Holmes, Dirk Adolph, Hui Zhang, Jürgen Margraf
Posttraumatic Stress Disorder (PTSD) is characterised by dysfunctional appraisals of the trauma and its consequences including one's own symptoms. Experimental studies have shown that Cognitive Bias Modification-Appraisal (CBM-App) training can reduce dysfunctional interpretations and analog trauma symptoms. One important question is how to enhance the effects of CBM-App. Following work suggesting that sleep has beneficial effects on consolidation processes and can thus improve learning, the present study investigated whether a brief period of sleep (i...
2018: PloS One
https://www.readbyqxmd.com/read/29446948/a-structure-activity-relationship-study-of-bitopic-n6-substituted-adenosine-derivatives-as-biased-adenosine-a1-receptor-agonists
#6
Luigi Aurelio, Jo-Anne Baltos, Leigh Ford, Anh T N Nguyen, Manuela Jörg, Shane M Devine, Celine Valant, Paul J White, Arthur Christopoulos, Lauren T May, Peter J Scammells
Herein, we investigate the structure-activity relationships of a series of compounds derived from the bitopic N6-substituted adenosine derivative 1, a previously reported biased ligand at the A1 adenosine receptor. Modifications were made to the orthosteric adenosine pharmacophore, the linker and the allosteric 2-amino-3-benzoylthiophene pharmacophore to probe the structure-activity relationships, both in terms of the effect of these modifications on biased signalling as well as receptor subtype selectivity...
February 15, 2018: Journal of Medicinal Chemistry
https://www.readbyqxmd.com/read/29446699/investigating-d-cycloserine-as-a-potential-pharmacological-enhancer-of-an-emotional-bias-learning-procedure
#7
Marcella L Woud, Simon E Blackwell, Susann Steudte-Schmiedgen, Michael Browning, Emily A Holmes, Catherine J Harmer, Jürgen Margraf, Andrea Reinecke
The partial N-methyl-D-aspartate receptor agonist d-cycloserine may enhance psychological therapies. However, its exact mechanism of action is still being investigated. Cognitive bias modification techniques allow isolation of cognitive processes and thus investigation of how they may be affected by d-cycloserine. We used a cognitive bias modification paradigm targeting appraisals of a stressful event, Cognitive Bias Modification-Appraisal, to investigate whether d-cycloserine enhanced the modification of appraisal, and whether it caused greater reduction in indices of psychopathology...
February 1, 2018: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/29446252/what-is-the-effect-of-exercise-on-wound-healing-in-patients-with-venous-leg-ulcers-a-systematic-review
#8
Daisy Smith, Rebecca Lane, Rosemary McGinnes, Jane O'Brien, Renea Johnston, Lyndal Bugeja, Victoria Team, Carolina Weller
Standard best practice for the treatment of venous leg ulcers (VLUs) is compression bandaging of the lower leg to reduce hydrostatic pressure. There is considerable variation in reported healing rates when using this gold-standard approach; therefore, a systematic and robust evaluation of other interventions is required. Exercise interventions, in addition to standard compression therapy, could improve wound-healing time and prevent their recurrence. We have conducted a systematic review to examine the effects of exercise on wound characteristics, including time to heal, size and recurrence, pain, quality of life, adverse events, and economic outcomes...
February 15, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29440567/cellular-and-molecular-mechanisms-of-centromere-drive
#9
Michael A Lampson, Ben E Black
The asymmetric outcome of female meiosis I, whereby an entire set of chromosomes are discarded into a polar body, presents an opportunity for selfish genetic elements to cheat the process and disproportionately segregate to the egg. Centromeres, the chromosomal loci that connect to spindle microtubules, could potentially act as selfish elements and "drive" in meiosis. We review the current understanding of the genetic and epigenetic contributions to centromere identity and describe recent progress in a powerful model system to study centromere drive in mice...
February 12, 2018: Cold Spring Harbor Symposia on Quantitative Biology
https://www.readbyqxmd.com/read/29435243/genotyping-strategy-matters-when-analyzing-hypervariable-major-histocompatibility-complex-experience-from-a-passerine-bird
#10
Silje L Rekdal, Jarl Andreas Anmarkrud, Arild Johnsen, Jan T Lifjeld
Genotyping of classical major histocompatibility complex (MHC) genes is challenging when they are hypervariable and occur in multiple copies. In this study, we used several different approaches to genotype the moderately variable MHC class I exon 3 (MHCIe3) and the highly polymorphic MHC class II exon 2 (MHCIIβe2) in the bluethroat (Luscinia svecica). Two family groups (eight individuals) were sequenced in replicates at both markers using Ion Torrent technology with both a single- and a dual-indexed primer structure...
February 2018: Ecology and Evolution
https://www.readbyqxmd.com/read/29433083/inhibition-of-phospholipases-influences-the-metabolism-of-wound-induced-benzylisoquinoline-alkaloids-in-papaver-somniferum-l
#11
Veronika Jablonická, Jörg Ziegler, Zuzana Vatehová, Desana Lišková, Ingo Heilmann, Marek Obložinský, Mareike Heilmann
Benzylisoquinoline alkaloids (BIAs) are important secondary plant metabolites and include medicinally relevant drugs, such as morphine or codeine. As the de novo synthesis of BIA backbones is (still) unfeasible, to date the opium poppy plant Papaver somniferum L. represents the main source of BIAs. The formation of BIAs is induced in poppy plants by stress conditions, such as wounding or salt treatment; however, the details about regulatory processes controlling BIA formation in opium poppy are not well studied...
January 31, 2018: Journal of Plant Physiology
https://www.readbyqxmd.com/read/29432784/cognitive-and-neuromodulation-strategies-for-unhealthy-eating-and-obesity-systematic-review-and-discussion-of-neurocognitive-mechanisms
#12
REVIEW
Laura Forcano, Fernanda Mata, Rafael de la Torre, Antonio Verdejo-Garcia
We systematically reviewed research on cognitive training and neuromodulation interventions for reducing food craving/intake, unhealthy diet and weight, and discussed their mechanisms of action. We reviewed 50 studies involving six cognitive trainings: Approach and Attentional Bias Modification, Implementation Intentions, Response Inhibition, Episodic Future Thinking and Working Memory; and four neuromodulation approaches: Transcranial Magnetic Stimulation (TMS), transcranial Direct Current Stimulation (tDCS), Deep Brain Stimulation (DBS) and Neurofeedback...
February 9, 2018: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/29432009/interfacial-modification-for-high-efficiency-vapor-phase-deposited-perovskite-solar-cells-based-on-metal-oxide-buffer-layer
#13
Daniel Pérez-Del-Rey, Pablo P Boix, Michele Sessolo, Afshin Hadipour, Henk J Bolink
Vacuum-deposition is one of the most technologically relevant techniques for the fabrication of perovskite solar cells. The most efficient vacuum-based devices rely on doped organic contacts, compromising the long-term stability of the system. Here, we introduce an inorganic electron transporting material to obtain power conversion efficiencies matching the best performing vacuum-deposited devices, with open circuit potential close to the thermodynamic limit. We analyze the leakage current reduction and the interfacial recombination improvement upon use of a thin (<10 nm) interlayer of C60, as well as a more favorable band alignment after a bias/UV light activation process...
February 12, 2018: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/29428819/modifying-mental-health-help-seeking-stigma-among-undergraduates-with-untreated-psychiatric-disorders-a-pilot-randomized-trial-of-a-novel-cognitive-bias-modification-intervention
#14
Ian H Stanley, Melanie A Hom, Thomas E Joiner
Help-seeking stigma is a potent barrier to the utilization of mental health services. This study aimed to determine if, compared to a psychoeducation condition, individuals randomized to a novel cognitive bias modification intervention for help-seeking stigma (CBM-HS) demonstrate greater reductions in help-seeking stigma, as well as increases in readiness to change and help-seeking behaviors. Participants included 32 undergraduates with a DSM-5 psychiatric disorder who denied past-year mental health treatment...
February 2, 2018: Behaviour Research and Therapy
https://www.readbyqxmd.com/read/29426035/exploring-the-pathway-from-anxiety-sensitivity-intervention-to-suicide-risk-reduction-chained-mediation-through-anxiety-and-depressive-symptoms
#15
Aaron M Norr, Nicholas P Allan, Greg M Reger, Norman B Schmidt
BACKGROUND: The suicide rate in the Unites States continues to increase suggesting novel intervention strategies are needed. Anxiety sensitivity (AS), or a fear of anxiety-related sensations, is a suicide risk factor that can be ameliorated via a single-session, computerized intervention called the Cognitive Anxiety Sensitivity Treatment (CAST). Results from randomized controlled trials have demonstrated that reductions in suicidal ideation (SI) due to CAST were mediated by AS reductions...
February 1, 2018: Journal of Affective Disorders
https://www.readbyqxmd.com/read/29422449/attention-bias-in-individuals-with-addictive-disorders-systematic-review-protocol
#16
Melvyn Zhang, JiangBo Ying, Guo Song, Roger Cm Ho, Daniel Ss Fung, Helen Smith
BACKGROUND: Globally, substance disorders, particularly that of opiate use, cannabis use, and stimulant use disorders, are highly prevalent. Psychological treatments are an integral aspect of intervention, but a proportion of individuals still relapse despite having received such an intervention. Recently, the dual-process theory proposed that the unconscious processes of attention biases are responsible for these relapses. Prior meta-analyses have reported the presence of attention bias in alcohol and tobacco use disorders...
February 8, 2018: JMIR Research Protocols
https://www.readbyqxmd.com/read/29413142/biobehavioral-markers-of-attention-bias-modification-in-temperamental-risk-for-anxiety-a-randomized-control-trial
#17
Pan Liu, Bradley C Taber-Thomas, Xiaoxue Fu, Koraly E Pérez-Edgar
OBJECTIVE: Children with behavioral inhibition, a temperament characterized by biologically based hypervigilance to novelty and social withdrawal, are at high risk for developing anxiety. This study examined the effect of a novel attention training protocol, attention bias modification (ABM), on symptomatic, behavioral, and neural risk markers in children with behavioral inhibition. METHOD: Nine- to 12-year-old typically developing children identified as having behavioral inhibition (N = 84) were assigned to a 4-session active ABM training (n = 43) or placebo protocol (n = 41) using a double-blinded, randomized, controlled trial approach...
February 2018: Journal of the American Academy of Child and Adolescent Psychiatry
https://www.readbyqxmd.com/read/29410605/barker-coded-node-pore-resistive-pulse-sensing-with-built-in-coincidence-correction
#18
Michael Kellman, Francois Rivest, Alina Pechacek, Lydia Sohn, Michael Lustig
A resistive pulse sensing device is able to extract quantities such as concentration and size distribution of particles, e.g. cells or microspheres, as they flow through the device's sensor region, i.e. channel, in an electrolyte solution. The dynamic range of detectable particle sizes is limited by the channel dimensions. In addition, signal interference from multiple particles transiting the channel simultaneously, i.e. coincidence event, further hinder the dynamic range. Coincidence data is often considered unusable and is discarded, reducing the throughput and introducing possible biases and errors into the distributions...
March 2017: Proceedings of the ... IEEE International Conference on Acoustics, Speech, and Signal Processing
https://www.readbyqxmd.com/read/29408051/working-mechanisms-of-a-general-positivity-approach-avoidance-training-effects-on-action-tendencies-as-well-as-on-subjective-and-physiological-stress-responses
#19
Gina R A Ferrari, Martin Möbius, Eni S Becker, J Spijker, Mike Rinck
BACKGROUND AND OBJECTIVES: The general positivity training, a Cognitive Bias Modification procedure modifying individuals' approach-avoidance tendencies to positively and negatively valenced pictures by means of a joystick task, has been proven effective in attenuating stress reactivity in dysphoric students. The present study explored which training component (pull positive pictures, push negative pictures, or both) is the active one in changing action tendencies and stress responses...
January 29, 2018: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/29402737/anxiety-and-threat-related-attention-cognitive-motivational-framework-and-treatment
#20
REVIEW
Karin Mogg, Brendan P Bradley
Research in experimental psychopathology and cognitive theories of anxiety highlight threat-related attention biases (ABs) and underpin the development of a computer-delivered treatment for anxiety disorders: attention-bias modification (ABM) training. Variable effects of ABM training on anxiety and ABs generate conflicting research recommendations, novel ABM training procedures, and theoretical controversy. This article summarises an updated cognitive-motivational framework, integrating proposals from cognitive models of anxiety and attention, as well as evidence of ABs...
February 2, 2018: Trends in Cognitive Sciences
keyword
keyword
56876
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"