Shota Harai, Susumu Hijioka, Reiko Yamada, Takeshi Ogura, Mitsuharu Fukasawa, Atsushi Okuda, Hideyuki Horike, Dai Inoue, Masanari Sekine, Yusuke Ishida, Takehiko Koga, Hidetoshi Kitamura, Yasuhito Tanaka, Motohiro Yoshinari, Katsumasa Kobayashi, Mark Chatto, Daiki Yamashige, Yuki Kawasaki, Yoshikuni Nagashio, Takuji Okusaka
BACKGROUND AND AIM: The 10-mm self-expandable metal stent (SEMS) is the standard for endoscopic transpapillary biliary drainage before pancreatic cancer surgery. However, the efficacy of stents thinner than 10 mm has not been adequately validated. Therefore, we aimed to evaluate the safety of a 6-mm fully covered SEMS (FCSEMS) for distal malignant biliary obstruction (DMBO) during preoperative chemotherapy for pancreatic cancer. METHODS: This was a single-arm, multicenter, prospective phase II study of endoscopic transpapillary initial biliary drainage for DMBO before pancreatic cancer surgery...
February 29, 2024: Journal of Gastroenterology and Hepatology