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Jun Xiong, Xiao Wei, Zi-Ming Liu, Ming-Wu Ding
A new one-pot preparation of polysubstituted imidazoles by a Staudinger/aza-Wittig/Ag(I)-catalyzed cyclization/isomerization has been developed. The easily accessible propargylazide derivatives reacted with triphenylphosphine, isocyanates, and amines sequentially to produce the fully substituted imidazoles in good overall yields in the presence of catalytic amount of AgNO3 /DMAP.
December 15, 2017: Journal of Organic Chemistry
Bikash Pal, Chun-Hsiung Chang, Cian-Jhe Zeng, Chih-Hsiu Lin
Pentacene is one of the most versatile organic semiconductors. New synthetic strategies to construct the pentacene skeleton are imperative to produce pentacene derivatives with appropriate solubility, stability, and optoelectronic properties for various applications. This paper describes a template-directed approach to pentacene derivatives. In the retrosynthesis, the acene skeleton is viewed as a laddered double strand polyene instead of the more intuitive linearly fused hexagons. Based on this vision, the template strand of polyene is constructed with Wittig olefination, whereas the second strand is accomplished with Knoevenagel condensation to produce pentacene and tetracene derivatives...
December 11, 2017: Chemistry: a European Journal
Luiz Henrique Gomes Matheus, Gislene Mendes Simão, Taíssa Altieri Amaral, Rodrigo Barbosa Oliveira Brito, Camila Soares Malta, Yves Silva Teles Matos, Alexandre Chagas Santana, Gabriela Gomes Cardoso Rodrigues, Maria Clara Albejante, Erna Elisabeth Bach, Maria Aparecida Dalboni, Cleber Pinto Camacho, Humberto Dellê
BACKGROUND: Indoleamine 2, 3-dioxygenase (IDO) is an immunomodulatory molecule that has been implicated in several biological processes. Although IDO has been linked with some renal diseases, its role in renal fibrosis is still unclear. Because IDO may be modulated by TGF-β1, a potent fibrogenic molecule, we hypothesized that IDO could be involved in renal fibrosis, especially acting in the TGF-β1-induced tubular epithelial-mesenchymal transition (EMT). We analyzed the IDO expression and activity in a model of renal fibrogenesis, and the effect of the IDO inhibitor 1-methyl-tryptophan (MT) on TGF-β1-induced EMT using tubular cell culture...
September 6, 2017: BMC Nephrology
Elizabeth Ekirapa-Kiracho, Ligia Paina, Rornald Muhumuza Kananura, Aloysius Mutebi, Pacuto Jane, Juliet Tumuhairwe, Moses Tetui, Suzanne N Kiwanuka
BACKGROUND: Saving groups are increasingly being used to save in many developing countries. However, there is limited literature about how they can be exploited to improve maternal and newborn health. OBJECTIVES: This paper describes saving practices, factors that encourage and constrain saving with saving groups, and lessons learnt while supporting communities to save through saving groups. METHODS: This qualitative study was done in three districts in Eastern Uganda...
August 2017: Global Health Action
Liang Ye, Arántzazu González-Campo, Tibor Kudernac, Rosario Núñez, Michel de Jong, Wilfred G van der Wiel, Jurriaan Huskens
Monolayer contact doping (MLCD) is a modification of the monolayer doping (MLD) technique that involves monolayer formation of a dopant-containing adsorbate on a source substrate. This source substrate is subsequently brought into contact with the target substrate, upon which the dopant is driven into the target substrate by thermal annealing. Here, we report a modified MLCD process, in which we replace the commonly used Si source substrate by a thermally oxidized substrate with a 100 nm thick silicon oxide layer, functionalized with a monolayer of a dopant-containing silane...
April 18, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
C F Guo, Y Wang, J H Liu, P Shen, H Wang, Y J Wei, X F Shi, X J Zhou, W W Wang
OBJECTIVE: To analyze the relationship between risk factors and prognosis of acute organophosphorus pesticide poisoning (AOPP). METHODS: The clinical data including APACHEⅡ, D-dimer, C-reactive protein, procalcitonin, lactic acid of the 67 cases of acute organophosphorus pesticide poisoning which respectively divided into survival group and death group by the outcome were collected. The independent influcing factors were got by logistic regression analysis. RESULTS: The analysis showed that APACHEⅡ, D-dimer、C-reactive protein and Procalcitonin were influencing factors to evaluate prognosis of AOPP (P<0...
May 20, 2016: Chinese Journal of Industrial Hygiene and Occupational Diseases
Danielle Y Ponzio, Corinne VanBeek, Justin C Wong, Eric M Padegimas, Okechukwu A Anakwenze, Charles L Getz, Joseph A Abboud
PURPOSE: To provide a baseline profile of current opinion on use of arthroscopic acromioplasty and evaluate the consistency of surgical decision making on whether or not to perform acromioplasty across different surgeon practices. METHODS: Twenty-two fellowship-trained orthopaedic shoulder surgeons from the Association of Clinical Elbow and Shoulder Surgeons completed an Internet-based survey on practices associated with acromioplasty, including questions related to 15 arthroscopic videos...
July 2016: Arthroscopy: the Journal of Arthroscopic & related Surgery
Shailesh P Puntambekar, S Katakdhond, S Galgali, A Iche, S Barik, A S Puntambekar
STUDY OBJECTIVE: To duplicate the steps of conventional multiport laparoscopic radical hysterectomy by 3 other minimal access modalities: robotic radical hysterectomy, laparoendoscopic single-site surgery (LESS), and orifice-assisted small-incision surgery (OASIS). DESIGN: Institutional Review Board approval was obtained. Between January 2009 and December 2012, the charts of the patients who had undergone radical hysterectomy by these 4 minimal access modalities were analyzed...
May 2015: Journal of Minimally Invasive Gynecology
M Geiger, K Deloose, J Callaert, M Bosiers
Surgical endarterectomy has been considered the prefered technique for treating the common femoral artery (CFA). Although favorable endovascular treatment results of the CFA have recently become available, losing the groin area as an important acess site is still the major concern for this technique to become the golden standart. Nevertheless, the endovascular approach has shown, through several studies, including our experience, the capacity to establish itself as a complementery treatment for the modern vascular surgeon...
February 2015: Journal of Cardiovascular Surgery
Joyce S Sabari, Diego Ortiz, Katie Pallatto, Joanna Yagerman, Sofya Glazman, Ivan Bodis-Wollner
PURPOSE: This descriptive study examined differences in health quality of life (HQoL) and activity engagement in two groups of people with Parkinson's disease (PD): those who regularly participated in classes offered by the community-based program, Brooklyn Parkinson's Group (BPg), and a comparison group. Individuals in the comparison group did not participate in any community-based programs for people with PD, and were recruited from a clinic for PD and related disorders (PDRD) in an urban medical center...
2015: Disability and Rehabilitation
Daniel C Acevedo, E Scott Paxton, Gerald R Williams, Joseph A Abboud
Many patients with rotator cuff tears have questions for their surgeons regarding the surgical procedure, perioperative management, restrictions, therapy, and ability to work after a rotator cuff repair. The purpose of our study was to determine common clinical practices among experts regarding rotator cuff repair and to assist them in counseling patients. We surveyed 372 members of the American Shoulder and Elbow Surgeons (ASES) and the Association of Clinical Elbow and Shoulder Surgeons (ACESS); 111 members (29...
July 16, 2014: Journal of Bone and Joint Surgery. American Volume
Matthew R Tucker, Farshad Roodbarkelari, Elisabeth Truernit, Nikolai M Adamski, Annika Hinze, Barbara Lohmüller, Tobias Würschum, Thomas Laux
BACKGROUND: Stem cells located in the centre of the shoot apical meristem are required for the repetitive formation of new organs such as leaves, branches and flowers. In Arabidopsis thaliana, the ZWILLE/PINHEAD/AGO10 (ZLL) gene encodes a member of the ARGONAUTE (AGO) protein family and is required to maintain shoot meristem stem cells during embryogenesis. In the Landsberg erecta (Ler) acession, ZLL is essential for stem cell maintenance, whereas in the Columbia (Col) accession its requirement appears masked by genetic modifiers...
2013: BMC Genomics
Marie Monique Bruère Paiva, Vilma Villarouco
Physical spaces need to be adjusted to suit the changes of a physical, cognitive and emotional order occasioned by the natural aging of people. Ergonomics of the built environment contributes to improving the interaction of the user and physical environment, with a view to their comfort and safety. By thinking through the influence that environments have on the quality of life of the elderly, this article presents an assessment of accessibility in private units--bedrooms and bathrooms--of a Long-Stay Institution for the Elderly (ILPI in Portuguese) in Portugal...
2012: Work: a Journal of Prevention, Assessment, and Rehabilitation
Jingjing Li, Bin Sun, Jinfeng Ouyang, Ying Chen, Hu Han, Kaiyu Liu, Yi Li
Human bocavirus (HBoV) is a recently discovered parvovirus, which is suspected to be an etiologic agent of respiratory disease and gastrointestinal disease in human. In the present study, we screened 941 nasopharyngeal aspirates collected from hospitalized children with lower respiratory tract infections from October 9, 2007 to March 20, 2009 in the Children's Hospital of Hubei Province. Our results showed that 33 of 941 samples (3.51%) were detected positive for HBoV. To obtain a full-length HBoV clone, three segments which covered the nearly full-length genome were amplified by PCR from HBoV positive samples separately and cloned into pBluescript SK II vector, and the resulting plasmid was designated as pWHL-1 (GenBank Acession No...
June 2011: Sheng Wu Gong Cheng Xue Bao, Chinese Journal of Biotechnology
Kun Xia, Rong-Jing Ding, Da-Yi Hu, Xin-Chun Yang, Le-Feng Wang
OBJECTIVES: To compare the safety and efficacy of radial artery access versus femoral artery access for percutaneous coronary intervention in acute myocardial infarction population. METHODS: From June 2004 to December 2006, 446 patients with acute myocardial infarction treated with percutaneous stenting were reviewed retrospectively. The radial artery approach was used in 242 patients, and the femoral artery approach in 204 patients. The success of the procedure, procedure duration, X-ray exposition, volume of contrast, incidence of major adverse cardiac events and complications were compared between the radial artery and femoral artery approach...
June 2011: Zhonghua Nei Ke za Zhi [Chinese Journal of Internal Medicine]
Lucas Zago Naves, Fernanda Ribeiro Santana, Carolina Guimarães Castro, Andréa Dolores Correia Miranda Valdivia, Adérito Soares Da Mota, Carlos Estrela, Lourenço Correr-Sobrinho, Carlos José Soares
Morphology, etching patterns, surface modification, and characterization of 2 different fiber posts: Gfp, Glass fiber post; and Cfp, carbon fiber were investigated by SEM analysis, after different surface treatments. Thirty fiber posts, being 15 Gfp and 15 Cfp were divided into a 5 surface treatments (n = 3): C-alcohol 70% (control); HF 4%-immersion in 4% hydrofluoric acid for 1min; H(3) PO(4) 37%-immersion in 37% phosphoric acid for 30s; H(2) O(2) 10%-immersion in 10% hydrogen peroxide for 20 min; H(2) O(2) 24%-immersion in 24% hydrogen peroxide for 10 min...
December 2011: Microscopy Research and Technique
M Van Hulten, S Ahmad, E Luna-Diez, R G Weeks, C M Pieterse, J Ton
No abstract text is available yet for this article.
2009: Communications in Agricultural and Applied Biological Sciences
Marcus Vinicius Dantas de Campos Martins, James Skinovsky, Djalma Ernesto Coelho
BACKGROUND: To present a new device for the execution of Laparoscopic Cholecystectomy. METHODS: In October 2008 was performed the first human Single Trocar Acess - Sitracc Cholecystectomy, in a female patient. The operation consisted in the classical steps of a laparoscopic cholecystectomy, using special flexible instruments and a 5 mm optical device. RESULTS: The operative time was 64 minutes. There were no important complications at the post-operative phase...
April 2009: Revista do Colégio Brasileiro de Cirurgiões
Erick Joel Reyes Morelos, Enrique Paredes Cruz, Margarita Guerrero Hernández
OBJECTIVE: The purpose of this study was to determine the yield of open access endoscopy in a third level Mexican hospital. BACKGROUND DATA: Open access endoscopy is common in United States of America and Europe (endoscopy is performed without prior specialist consultation). In Mexico this system hasn't become popular yet. The usefulness of open access endoscopy has been questioned. Some indications for upper gastrointestinal endoscopy (UGE) aren't included in the guidelines for appropriate use of endoscopy...
October 2006: Revista de Gastroenterología de México
Juliano T V Resende, Wilson Roberto Maluf, Maria das Graças Cardoso, David L Nelson, Marcos Ventura Faria
Acylsugars present in Lycopersicon pennellii are responsible for the high levels of pest resistance often found in this wild tomato taxon. We investigated the inheritance of acylsugar contents in segregating populations of the interspecific tomato cross L. esculentum x L. pennellii and estimated correlations between leaflet acylsugar contents and the levels of mite repellence. Acylsugar contents were quantified with the Sommogy-Nelson colorimetric method in the acessions L. esculentum 'TOM-584' (P(1), low acylsugars), L...
2002: Genetics and Molecular Research: GMR
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