keyword
https://read.qxmd.com/read/38518704/multimodal-imaging-and-genetic-characteristics-of-autosomal-recessive-bestrophinopathy
#21
JOURNAL ARTICLE
K Tekin, S C Dulger, T Horozoglu Ceran, M Inanc, P C Ozdal, M Y Teke
PURPOSE: To report the ocular manifestations, multimodal imaging characteristics and genetic testing results of six patients with autosomal recessive bestrophinopathy (ARB). METHODS: This was an observational case series including 12 eyes of 6 patients who were diagnosed with ARB. All patients underwent a complete ophthalmic examination including refraction, slit-lamp biomicroscopy, dilated fundus examination, fundus autofluorescence, optical coherence tomography and electrooculography...
March 21, 2024: Journal Français D'ophtalmologie
https://read.qxmd.com/read/38518004/bilateral-total-iris-atrophy-corneal-decompensation-and-glaucoma-following-bilateral-cosmetic-artificial-iris-implantation-a-case-report-of-severe-sequela-and-successful-management
#22
JOURNAL ARTICLE
Wisam Shihadeh, Abdelwahab Aleshawi, Yara Aburamadan, Mohammed Al-Shalakhti
PURPOSE: Cosmetic iris implants have a record of high ocular complications and are no longer in use. These complications include glaucoma, corneal decompensation, iris atrophy, uveitis, cataract and retinal detachment. CASE PRESENTATION: We report a case of a 44-year-old lady presented with bilateral total iris atrophy, glaucoma and corneal decompensation after cosmetic artificial iris implantation. The patient underwent bilateral artificial iris removal, glaucoma drainage device for the right eye, and micropulse laser for the left eye...
March 22, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38516283/quantifying-fluid-and-function-in-suboptimal-responders-switched-from-an-anti-vascular-endothelial-growth-factor-vegf-to-faricimab
#23
JOURNAL ARTICLE
David Sutter, Abigail Anderson, Sheila Wheatley, Veeral Sheth
Background Anti-vascular endothelial growth factor (VEGF) injections have been successful in reducing vision loss from neovascular age-related macular degeneration, a leading cause of blindness. Due to the high treatment burden and suboptimal responses, switching to bi-specific faricimab treatment may lead to improved outcomes. Methods This retrospective chart review evaluated if suboptimal responders to anti-VEGF injections had better outcomes when switched to faricimab. Suboptimal responders were defined as patients with a history of >3 months of injections and the presence of fluid after ≥3 injections...
March 2024: Curēus
https://read.qxmd.com/read/38516053/pseudoxanthoma-elasticum-associated-angioid-streaks-near-a-scleral-buckle
#24
Karen E Lee, Tobin B T Thuma, Mirataollah Salabati, Meera D Sivalingam, Jose S Pulido, Kammi B Gunton
PURPOSE: We report a patient with pseudoxanthoma elasticum (PXE) with angioid streaks near a scleral buckle site. OBSERVATIONS: A 46-year-old male with PXE presented for evaluation of blurry vision and was found to have classic PXE findings in both eyes and angioid streaks adjacent to the site of a scleral buckle in his left eye. He underwent multimodal imaging, genetic testing, and intravitreal aflibercept in the right eye. CONCLUSIONS AND IMPORTANCE: Bruch's membrane is known to be fragile in PXE, and patients are often counseled about the heightened risk of playing contact sports...
June 2024: American Journal of Ophthalmology Case Reports
https://read.qxmd.com/read/38513246/introducing-a-customized-low-cost-macular-buckle
#25
JOURNAL ARTICLE
Friederike C Kortuem, Focke Ziemssen, Jonas Neubauer, Karl Ulrich Bartz-Schmidt, Spyridon Dimopoulos
PURPOSE: To demonstrate a novel surgical technique that is a low-cost alternative to commercial implants for macular buckling in high myopia. METHODS: A silicon encircling band serves as the anchor. A second silicon circling band is employed, with a 10mm silicon strip to widen the posterior scleral indentation. This band is inserted posteriorly the lateral and inferior rectus muscles and pushed behind the globe, orienting it in a superior-temporal to inferio-nasal position with the silicone strip directly under the macula...
March 20, 2024: Retina
https://read.qxmd.com/read/38512501/posterior-vitreous-detachment-rates-post-uncomplicated-phacoemulsification-surgery-a-systematic-review
#26
JOURNAL ARTICLE
Daire J Hurley, Patrick Murtagh, Marc Guerin
PURPOSE: It is commonly accepted that phacoemulsification surgery is a risk factor for the development of posterior vitreous detachment (PVD) and may accelerate the process. This is an important consideration particularly in cases involving young patients who pre-operatively have no PVD, given the increased risk of retinal tears and detachments. METHODS: A comprehensive literature search was conducted to identify studies reporting incidence of PVD post-uncomplicated phacoemulsification surgery...
March 21, 2024: International Ophthalmology
https://read.qxmd.com/read/38509989/retina-images-classification-based-on-2d-empirical-mode-decomposition-and-multifractal-analysis
#27
JOURNAL ARTICLE
Lei Yang, Minxuan Zhang, Jing Cheng, Tiegang Zhang, Feng Lu
Diabetic retinopathy is an ocular disease caused by long-term damage to the retina due to high blood sugar levels. Elevated blood sugar can impair the microvasculature in the retina, leading to vascular abnormalities and the formation of abnormal new blood vessels. These changes can manifest in the retina as hemorrhages, leaks, vessel dilation, retinal edema, and retinal detachment. The retinas of individuals with diabetes exhibit different morphologies compared to those without the condition. Most histological images cannot be accurately described using traditional geometric shapes or methods...
March 30, 2024: Heliyon
https://read.qxmd.com/read/38509616/uveal-effusion-syndrome-a-case-report
#28
JOURNAL ARTICLE
Brittany Hodges, Felix Omoruyi, Karen Allison
BACKGROUND: This case report is applicable to the field of ophthalmology because there is a paucity of medical literature related to the clinical presentation, diagnosis, and management of uveal effusion syndrome. This is an urgent concern because there are severe complications associated with this disease, including non-rhegmatogenous retinal detachment, angle closure glaucoma, and possible blindness. This report will fill clinical knowledge gaps using a patient example. CASE PRESENTATION: A 68-year-old white male with multiple cardiovascular risk factors initially presented to the Eye Institute Urgent Care Clinic with new onset visual symptoms, including eye pain, eye lid swelling, redness, and tearing of his left eye...
March 21, 2024: Journal of Medical Case Reports
https://read.qxmd.com/read/38504919/the-role-of-age-in-ocular-toxoplasmosis-clinical-signs-of-immunosenescence-and-inflammaging
#29
JOURNAL ARTICLE
Armin Taghavi Eraghi, Justus G Garweg, Uwe Pleyer
PURPOSE: This study aimed to investigate the association between age, immune response, and clinical presentation of ocular toxoplasmosis (OT). DESIGN: This was a monocentric, retrospective, observational cohort study. METHODS: A review of the medical records of patients with active OT at the Uveitis Center, Charité Universitätsmedizin, was conducted. Baseline parameters included age at presentation, visual acuity, intraocular pressure (IOP), size and location of active lesions, inflammatory activity, antibody index (AI), and complications of intraocular inflammation...
2024: Frontiers in Medicine
https://read.qxmd.com/read/38502928/inverted-internal-limiting-membrane-flap-coverage-with-autologous-blood-technique-after-air-fluid-exchange-and-silicone-oil-tamponade-for-extensive-macular-hole-retinal-detachment-in-highly-myopic-eyes
#30
JOURNAL ARTICLE
Jiwei Tao, Shixin Zhao, Xiangjun She, Zhe Lv, Yun Zhang
PURPOSE: To report a technique consisting of inverted internal limiting membrane (ILM) flap coverage with autologous blood after air-fluid exchange and silicone oil tamponade in treating extensive retinal detachment (RD) secondary to a myopic macular hole (MH). METHODS: Retrospective case series. The technique was applied in 18 eyes with MH-RD extending beyond the equator with a minimum follow-up of 6 months. The procedures for pars plan vitrectomy (PPV) included the following:1) the ILM was peeled to the superior and inferior arcade margins, and except for the ILM in the temporal region, was hinged toward the edge of the MH...
March 4, 2024: Retina
https://read.qxmd.com/read/38496190/atypical-peripheral-retinal-necrosis-without-ocular-inflammation-and-retinal-whitening-in-a-patient-with-acute-myelogenous-leukemia-a-case-report
#31
Yoshihiro Nakagawa, Xue Tan, Hikari Yoshida, Takahiro Suzuki, Yasuyuki Suzuki
Retinal necrosis is a severe condition that threatens visual function. It is caused by viruses that are known to cause acute retinal necrosis (ARN) and progressive outer retinal necrosis (PORN), which are called necrotizing herpetic retinopathies (NHR). ARN causes severe intraocular inflammation, including anterior chamber intravitreal cells, keratic precipitate, vitreous opacity, and retinal vasculitis, whereas intraocular inflammation in PORN is considered mild or virtually absent. In addition, PORN is a disease that manifests in immunosuppressive patients, such as those with acquired immunodeficiency syndrome...
February 2024: Curēus
https://read.qxmd.com/read/38492583/clinical-therapeutics-for-proliferative-vitreoretinopathy-in-retinal-detachment
#32
REVIEW
Francesco Sabatino, Philip Banerjee, Mahiul M K Muqit
Proliferative vitreoretinopathy (PVR) is an abnormal and prolonged healing response to retinal injury (retinal detachment, post-retinal detachment surgery) characterised by: pre/subretinal membrane formation; retinal gliosis and retinal shortening, retinal pigment epithelium cell proliferation; and increased glial (mainly Mu¨ller cells), fibroblast and inflammatory cell (macrophage, lymphocyte) activity, leading to tractional retinal holes/breaks and multiple costly eye operations suffered by patients...
March 14, 2024: Survey of Ophthalmology
https://read.qxmd.com/read/38492122/retinal-complications-post-posterior-chamber-phakic-intraocular-lens-implantation-at-a-tertiary-eye-hospital-in-the-eastern-province-of-saudi-arabia
#33
JOURNAL ARTICLE
Mohanna Aljindan, Nada Albalawi, Fatimah Alzaher, Jumana Hariri, Halah Bin Helayel, Majed Fehaid Alsubaie, Omar Khan, Aysha Aloqab, Ghufran Alarfaj, Naif M Sulaimani
PURPOSE: Phakic intraocular lenses treat higher degrees of myopia not possible previously with conventional refractive surgery. The aim of this study is to report the incidence and risk factors of retinal complications after posterior chamber PIOL implantation and assess the differences in biometric parameters between patients who developed such complications versus those who did not. METHODS: This retrospective study recruited 514 patients who underwent ICL implantation to correct myopia at a tertiary eye hospital center in the Eastern province of Saudi Arabia...
March 16, 2024: International Ophthalmology
https://read.qxmd.com/read/38489304/internal-limiting-membrane-peeling-in-rhegmatogenous-retinal-detachment-a-meta-analysis
#34
JOURNAL ARTICLE
Guohai Chen, Radouil Tzekov, Yan Fang, Yuhua Tong, Wensheng Li
PURPOSE: To determine whether pars plana vitrectomy (PPV) with internal limiting membrane (ILM) peeling for rhegmatogenous retinal detachment (RRD) could get better functional and anatomical outcomes. METHODS: A comprehensive literature search was performed to find relevant studies. A meta-analysis was conducted by comparing the weighted mean differences (WMD) in the mean change of best corrected visual acuity (BCVA) from baseline and calculating the odd ratios (OR) for rates of epiretinal membrane (ERM) formation and recurrence of retinal detachment (RD)...
2024: PloS One
https://read.qxmd.com/read/38488250/face-down-positioning-or-posturing-after-pars-plana-vitrectomy-for-macula-involving-rhegmatogenous-retinal-detachments
#35
REVIEW
Timothy Hm Fung, Tsz Wing Yim, Noemi Lois, David M Wright, Su-Hsun Liu, Tom Williamson
BACKGROUND: A macula-involving rhegmatogenous retinal detachment (RRD) is one of the most common ophthalmic surgical emergencies and causes significant visual morbidity. Pars plana vitrectomy (PPV) with gas tamponade is often performed to repair primary macula-involving RRDs with a high rate of anatomical retinal reattachment. It has been advocated by some ophthalmologists that face-down positioning after PPV and gas tamponade helps reduce postoperative retinal displacement. Retinal displacement can cause metamorphopsia and binocular diplopia...
March 15, 2024: Cochrane Database of Systematic Reviews
https://read.qxmd.com/read/38486220/effect-of-silicone-oil-versus-gas-tamponade-on-macular-layer-microstructure-after-pars-plana-vitrectomy-for-macula-on-rhegmatogenous-retinal-detachment
#36
JOURNAL ARTICLE
Abdulaziz Mohammed Al-Shehri, Saud Aljohani, Khalid Abdulaziz Aldihan, Musa Johaiman Alrashedi, Saad Alrasheed, Patrik Schatz
PURPOSE: To analyze structural changes in the macular retinal layers and sub-foveal choroidal thickness (SFCT) in eyes after macula-on rhegmatogenous retinal detachment (RRD) repair by pars plana vitrectomy with either silicone oil (SO) or gas tamponade, and the effect of these changes on visual acuity. PATIENTS AND METHODS: Retrospective study which included 26 eyes in the SO Group and 32 in the Gas Group. Optical coherence tomography (OCT) scans of the affected eyes were obtained before surgery, and 3 months after PPV in the Gas Group, and during silicone oil in situ and 3 months after SO removal, in the SO Group...
March 14, 2024: BMC Ophthalmology
https://read.qxmd.com/read/38485969/retinal-detachment
#37
REVIEW
Jonathan B Lin, Raja Narayanan, Elise Philippakis, Yoshihiro Yonekawa, Rajendra S Apte
Retinal detachment (RD) occurs when the neurosensory retina, the neurovascular tissue responsible for phototransduction, is separated from the underlying retinal pigment epithelium (RPE). Given the importance of the RPE for optimal retinal function, RD invariably leads to decreased vision. There are three main types of RD: rhegmatogenous, tractional and exudative (also termed serous) RD. In rhegmatogenous RD, one or more retinal breaks enable vitreous fluid to enter the subretinal space and separate the neurosensory retina from the RPE...
March 14, 2024: Nature Reviews. Disease Primers
https://read.qxmd.com/read/38485941/retinal-detachment
#38
JOURNAL ARTICLE
(no author information available yet)
No abstract text is available yet for this article.
March 14, 2024: Nature Reviews. Disease Primers
https://read.qxmd.com/read/38485215/using-artificial-intelligence-to-improve-human-performance-efficient-retinal-disease-detection-training-with-synthetic-images
#39
JOURNAL ARTICLE
Hitoshi Tabuchi, Justin Engelmann, Fumiatsu Maeda, Ryo Nishikawa, Toshihiko Nagasawa, Tomofusa Yamauchi, Mao Tanabe, Masahiro Akada, Keita Kihara, Yasuyuki Nakae, Yoshiaki Kiuchi, Miguel O Bernabeu
BACKGROUND: Artificial intelligence (AI) in medical imaging diagnostics has huge potential, but human judgement is still indispensable. We propose an AI-aided teaching method that leverages generative AI to train students on many images while preserving patient privacy. METHODS: A web-based course was designed using 600 synthetic ultra-widefield (UWF) retinal images to teach students to detect disease in these images. The images were generated by stable diffusion, a large generative foundation model, which we fine-tuned with 6285 real UWF images from six categories: five retinal diseases (age-related macular degeneration, glaucoma, diabetic retinopathy, retinal detachment and retinal vein occlusion) and normal...
March 14, 2024: British Journal of Ophthalmology
https://read.qxmd.com/read/38485214/validation-of-a-deep-learning-model-for-automatic-detection-and-quantification-of-five-oct-critical-retinal-features-associated-with-neovascular-age-related-macular-degeneration
#40
JOURNAL ARTICLE
Federico Ricardi, Jonathan Oakley, Daniel Russakoff, Giacomo Boscia, Paolo Caselgrandi, Francesco Gelormini, Andrea Ghilardi, Giulia Pintore, Tommaso Tibaldi, Paola Marolo, Francesco Bandello, Michele Reibaldi, Enrico Borrelli
PURPOSE: To develop and validate a deep learning model for the segmentation of five retinal biomarkers associated with neovascular age-related macular degeneration (nAMD). METHODS: 300 optical coherence tomography volumes from subject eyes with nAMD were collected. Images were manually segmented for the presence of five crucial nAMD features: intraretinal fluid, subretinal fluid, subretinal hyperreflective material, drusen/drusenoid pigment epithelium detachment (PED) and neovascular PED...
March 14, 2024: British Journal of Ophthalmology
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