keyword
MENU ▼
Read by QxMD icon Read
search

Biomedical hiv prevention

keyword
https://www.readbyqxmd.com/read/28729520/challenges-and-emerging-opportunities-for-the-hiv-prevention-treatment-and-care-cascade-in-men-who-have-sex-with-men-in-asia-pacific
#1
REVIEW
Frits van Griensven, Thomas E Guadamuz, Jan Willem de Lind van Wijngaarden, Nittaya Phanuphak, Sunil Suhas Solomon, Ying-Ru Lo
In Asia Pacific, most countries have expanded HIV treatment guidelines to include all those with HIV infection and adopted antiretroviral treatment for prevention (TFP) as a blanket strategy for HIV control. Although the overall epidemic development associated with this focus is positive, the HIV epidemic in men who have sex with men (MSM) is continuing unperturbed without any signs of decline or reversal. This raises doubt about whether TFP as a blanket HIV prevention policy is the right approach. This paper reviews currently available biomedical HIV prevention strategies, national HIV prevention policies and guidelines from selected countries and published data on the HIV cascade in MSM...
August 2017: Sexually Transmitted Infections
https://www.readbyqxmd.com/read/28701272/sexually-transmitted-infections-challenges-ahead
#2
REVIEW
Magnus Unemo, Catriona S Bradshaw, Jane S Hocking, Henry J C de Vries, Suzanna C Francis, David Mabey, Jeanne M Marrazzo, Gerard J B Sonder, Jane R Schwebke, Elske Hoornenborg, Rosanna W Peeling, Susan S Philip, Nicola Low, Christopher K Fairley
WHO estimated that nearly 1 million people become infected every day with any of four curable sexually transmitted infections (STIs): chlamydia, gonorrhoea, syphilis, and trichomoniasis. Despite their high global incidence, STIs remain a neglected area of research. In this Commission, we have prioritised five areas that represent particular challenges in STI treatment and control. Chlamydia remains the most commonly diagnosed bacterial STI in high-income countries despite widespread testing recommendations, sensitive and specific non-invasive testing techniques, and cheap effective therapy...
July 7, 2017: Lancet Infectious Diseases
https://www.readbyqxmd.com/read/28682799/online-to-offline-models-in-hiv-service-delivery
#3
Tarandeep Anand, Chattiya Nitpolprasert, Nittaya Phanuphak
PURPOSE OF REVIEW: Half the world's population has access to Internet and technologies, and utilization is near-ubiquitous among providers and key populations. Despite being so well connected; identifying, reaching and linking vulnerable populations to HIV clinical services remains a global challenge. This review highlights the emerging online-to-offline (O2O) models, their potential in scaling up services, and evaluating impact, and implications for future research. RECENT FINDINGS: Globally, four major types of O2O models have been implemented, primarily in the West and Asia, especially among MSM and transgender women...
July 5, 2017: Current Opinion in HIV and AIDS
https://www.readbyqxmd.com/read/28659069/hiv-aids-discourses-in-kyrgyzstan-s-policy-arena
#4
Svetlana Ancker, Martin McKee, Bernd Rechel
This article explores the major discourses on HIV/AIDS in the policy arena in Kyrgyzstan, a former Soviet country in Central Asia that has experienced a rapid rise in HIV infections since the early 2000s. Based on an analysis of policy documents and 54 semi-structured in-depth interviews with key stakeholders in the area of HIV/AIDS policies in Kyrgyzstan, we distinguish a number of key discourses, competing for legitimacy and authority. While some of these discourses have been used in other countries (such as those presenting HIV/AIDS as a biomedical, social or moral issue), others are more specific to Kyrgyzstan (such as a discourse presenting the country as a regional pioneer in HIV/AIDS prevention efforts)...
June 28, 2017: Global Public Health
https://www.readbyqxmd.com/read/28653286/user-input-in-iterative-design-for-prevention-product-development-leveraging-interdisciplinary-methods-to-optimize-effectiveness
#5
Kate M Guthrie, Rochelle K Rosen, Sara E Vargas, Melissa Guillen, Arielle L Steger, Melissa L Getz, Kelley A Smith, Jaime J Ramirez, Erna M Kojic
The development of HIV-preventive topical vaginal microbicides has been challenged by a lack of sufficient adherence in later stage clinical trials to confidently evaluate effectiveness. This dilemma has highlighted the need to integrate translational research earlier in the drug development process, essentially applying behavioral science to facilitate the advances of basic science with respect to the uptake and use of biomedical prevention technologies. In the last several years, there has been an increasing recognition that the user experience, specifically the sensory experience, as well as the role of meaning-making elicited by those sensations, may play a more substantive role than previously thought...
June 26, 2017: Drug Delivery and Translational Research
https://www.readbyqxmd.com/read/28649869/hivr4p-2016-partnering-for-prevention-conference-summary-and-highlights
#6
Barbara L Shacklett, Cynthia A Derdeyn, Morenike Oluwatoyin Folayan, Raphael Landovitz, Colin Anthony, Anna-Janina Behrens, Thomas Hope, Elise Landais, Lorna Leal, Jeanne M Marrazzo, Lynn Morris, Nelly Mugo, Kenneth Ngure, Veronica Noseda, Srinika Ranasinghe, Damien C Tully, Yegor Voronin, Mitchell Warren, Constantinos Kurt Wibmer, Irene Y Xie, Gabriella Scarlatti, Bargavi Thyagarajan
HIV Research for Prevention: AIDS Vaccine, Microbicide and ARV-based Prevention Science (HIVR4P) was built upon a growing consensus that effective HIV prevention requires a combination of approaches and that understanding, analyzing and debating the cross-cutting issues that impact prevention research are all essential to combat the global HIV/AIDS epidemic. To that end, the biennial HIVR4P conference is dedicated to all biomedical HIV prevention research approaches, including HIV vaccines, microbicides, PrEP and treatment as prevention...
June 24, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28631059/trends-in-hiv-risk-testing-and-treatment-among-msm-in-chicago-2004-2014-implications-for-hiv-elimination-planning
#7
Ethan Morgan, Britt Skaathun, Nicola Lancki, Antonio D Jimenez, Jesus Ramirez-Valles, Ramona Bhatia, Stephanie Masiello-Schuette, Nanette Benbow, Nikhil Prachand, John A Schneider
Men who have sex with men (MSM) in the USA continue to have high rates of HIV infection. Increasingly, in addition to behavioral factors, biomedical interventions have been found to play important roles in HIV prevention. In this analysis, we used four waves of cross-sectional data (2004, 2008, 2011, and 2014) from the National HIV Behavioral Surveillance System (NHBS) to examine trends in key behaviors and biomedical interventions among MSM in Chicago (N = 3298). Logistic regression was used to determine changes in behaviors and use of biomedical interventions...
June 19, 2017: Journal of Urban Health: Bulletin of the New York Academy of Medicine
https://www.readbyqxmd.com/read/28605174/-now-that-you-are-circumcised-you-cannot-have-first-sex-with-your-wife-post-circumcision-sexual-behaviours-and-beliefs-among-men-in-wakiso-district-uganda
#8
Simon Peter Sebina Kibira, Lynn Muhimbuura Atuyambe, Ingvild Fossgard Sandøy, Fredrick Edward Makumbi, Marguerite Daniel
INTRODUCTION: Safe male circumcision is an important biomedical intervention in the comprehensive HIV prevention programmes implemented in 14 sub-Saharan African countries with high HIV prevalence. To sustain its partial protective benefit, it is important that perceived reduced HIV risk does not lead to behavioural risk compensation among circumcised men and their sexual partners. This study explored beliefs that may influence post circumcision sexual behaviours among circumcised men in a programme setting...
June 5, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28591513/unravelling-the-molecular-basis-of-high-affinity-nanobodies-against-hiv-p24-in-vitro-functional-structural-and-in-silico-insights
#9
Eleanor R Gray, Jennifer C Brookes, Christophe Caillat, Valérian Turbé, Benjamin L J Webb, Luke A Granger, Benjamin S Miller, Laura E McCoy, Mohamed El Khattabi, C Theo Verrips, Robin A Weiss, Dorothy M Duffy, Winfried Weissenhorn, Rachel A McKendry
Preventing the spread of infectious diseases remains an urgent priority worldwide, and this is driving the development of advanced nanotechnology to diagnose infections at the point of care. Herein, we report the creation of a library of novel nanobody capture ligands to detect p24, one of the earliest markers of HIV infection. We demonstrate that these nanobodies, one tenth the size of conventional antibodies, exhibit high sensitivity and broad specificity to global HIV-1 subtypes. Biophysical characterization indicates strong 690 pM binding constants and fast kinetic on-rates, 1 to 2 orders of magnitude better than monoclonal antibody comparators...
July 14, 2017: ACS Infectious Diseases
https://www.readbyqxmd.com/read/28586567/ending-the-hiv-epidemic-with-the-help-of-biomedical-prevention-interventions
#10
Paula Toynton, Kathy Ahearn O'Brien
No abstract text is available yet for this article.
2017: MD Advisor: a Journal for New Jersey Medical Community
https://www.readbyqxmd.com/read/28570576/characteristics-of-hiv-target-cd4-t-cells-collected-using-different-sampling-methods-from-the-genital-tract-of-hiv-seronegative-women
#11
Smita S Iyer, Michael J Sabula, C Christina Mehta, Lisa B Haddad, Nakita L Brown, Rama R Amara, Igho Ofotokun, Anandi N Sheth
BACKGROUND: Understanding the immune profile of CD4 T cells, the primary targets for HIV, in the female genital tract (FGT) is critical for evaluating and developing effective biomedical HIV prevention strategies in women. However, longitudinal investigation of HIV susceptibility markers expressed by FGT CD4 T cells has been hindered by low cellular yield and risk of sampling-associated trauma. We investigated three minimally invasive FGT sampling methods to characterize and compare CD4 T cell yield and phenotype with the goal of establishing feasible sampling strategies for immune profiling of mucosal CD4 T cells...
2017: PloS One
https://www.readbyqxmd.com/read/28553295/developing-an-integrated-brief-biobehavioral-hiv-prevention-intervention-for-high-risk-drug-users-in-treatment-the-process-and-outcome-of-formative-research
#12
Roman Shrestha, Frederick Altice, Pramila Karki, Michael Copenhaver
To date, HIV prevention efforts have largely relied on singular strategies (e.g., behavioral or biomedical approaches alone) with modest HIV risk-reduction outcomes for people who use drugs (PWUD), many of whom experience a wide range of neurocognitive impairments (NCI). We report on the process and outcome of our formative research aimed at developing an integrated biobehavioral approach that incorporates innovative strategies to address the HIV prevention and cognitive needs of high-risk PWUD in drug treatment...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28492452/the-changing-landscape-of-hiv-prevention-in-the-united-states-health-department-experiences-and-local-adaptations-in-response-to-the-national-hiv-aids-strategy-and-high-impact-prevention-approach
#13
Holly H Fisher, Aba Essuon, Tamika Hoyte, Ekaterine Shapatava, Gene Shelley, Aisha Rios, Stephanie Beane, Stacey Bourgeois, Erica Dunbar, Tobey Sapiano
OBJECTIVE: HIV prevention has changed substantially in recent years due to changes in national priorities, biomedical advances, and health care reform. Starting in 2010, motivated by the National HIV/AIDS Strategy (NHAS) and the Centers for Disease Control and Prevention's (CDC's) High-Impact Prevention (HIP), health departments realigned resources so that cost-effective, evidence-based interventions were targeted to groups at risk in areas most affected by HIV. This analysis describes how health departments in diverse settings were affected by NHAS and HIP...
May 10, 2017: Journal of Public Health Management and Practice: JPHMP
https://www.readbyqxmd.com/read/28472981/infectious-diseases-of-poverty-the-first-five-years
#14
EDITORIAL
Wei Wang, Jin Chen, Hui-Feng Sheng, Na-Na Wang, Pin Yang, Xiao-Nong Zhou, Robert Bergquist
Although the focus in the area of health research may be shifting from infectious to non-communicable diseases, the infectious diseases of poverty remain a major burden of disease of global health concern. A global platform to communicate and share the research on these diseases is needed to facilitate the translation of knowledge into effective approaches and tools for their elimination. Based on the "One health, One world" mission, a new, open-access journal, Infectious Diseases of Poverty (IDP), was launched by BioMed Central in partnership with the National Institute of Parasitic Diseases (NIPD), Chinese Center for Disease Control and Prevention (China CDC) on October 25, 2012...
May 4, 2017: Infectious Diseases of Poverty
https://www.readbyqxmd.com/read/28470458/a-simple-risk-prediction-algorithm-for-hiv-transmission-results-from-hiv-prevention-trials-in-kwazulu-natal-south-africa-2002-2012
#15
Handan Wand, Tarylee Reddy, Sarita Naidoo, Suri Moonsamy, Samantha Siva, Neetha S Morar, Gita Ramjee
We aimed to develop a HIV risk scoring algorithm for targeted screening among women in South Africa. We used data from five biomedical intervention trials (N = 8982 Cox regression models were used to create a risk prediction algorithm and it was internally and externally validated using standard statistical measures; 7-factors were identified as significant predictors of HIV infection: <25 years old, being single/not cohabiting, parity (<3), age at sexual debut (<16), 3+ sexual partners, using injectables and diagnosis with a sexually transmitted infection(s)...
May 3, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28467163/perspectives-on-hiv-pre-and-post-exposure-prophylaxes-prep-and-pep-among-female-and-male-sex-workers-in-mombasa-kenya-implications-for-integrating-biomedical-prevention-into-sexual-health-services
#16
Arjee J Restar, Jack Ume Tocco, Joanne E Mantell, Yves Lafort, Peter Gichangi, Tsitsi B Masvawure, Sophie Vusha Chabeda, Theo G M Sandfort
Pre- and post-exposure prophylaxes (PrEP and PEP) can reduce the risk of HIV acquisition, yet often are inaccessible to and underutilized by most-vulnerable populations, including sex workers in sub-Saharan Africa. Based on in-depth interviews with 21 female and 23 male HIV-negative sex workers in Mombasa, Kenya, we found that awareness and knowledge of PrEP and PEP were low, although willingness to use both was high. Participants felt PrEP would be empowering and give added protection against infection, although some expressed concerns about side effects...
April 2017: AIDS Education and Prevention: Official Publication of the International Society for AIDS Education
https://www.readbyqxmd.com/read/28449588/disparities-in-hiv-knowledge-and-attitudes-toward-biomedical-interventions-among-the-non-medical-hiv-workforce-in-the-united-states
#17
Raniyah M Copeland, Phill Wilson, Gabriela Betancourt, David Garcia, Murray Penner, Rebecca Abravanel, Eric Y Wong, Lori D Parisi
Non-medical, community-based workers play a critical role in supporting people living with (or at risk of acquiring) HIV along the care continuum. The biomedical nature of promising advances in HIV prevention, such as pre-exposure prophylaxis and treatment-as-prevention, requires frontline workers to be knowledgeable about HIV science and treatment. This study was developed to: measure knowledge of HIV science and treatment within the HIV non-medical workforce, evaluate workers' familiarity with and attitudes toward recent biomedical interventions, and identify factors that may affect HIV knowledge and attitudes...
April 27, 2017: AIDS Care
https://www.readbyqxmd.com/read/28449198/systematic-review-of-sex-work-interventions-in-sub-saharan-africa-examining-combination-prevention-approaches
#18
REVIEW
George Awungafac, Therese Delvaux, Bea Vuylsteke
OBJECTIVE: The incidence of HIV and sexually transmitted infections is disproportionately high among sex workers (SW). We aimed to update the evidence on the effectiveness of SW interventions in sub-Saharan Africa and to provide more insights into combination prevention. METHODS: The Systematic review followed PRISMA guidelines in a search of PUBMED and POPLINE for peer-reviewed literature published between 1 January 2000 and 22 July 2016 (registration number on PROSPERO: CRD42016042529)...
April 27, 2017: Tropical Medicine & International Health: TM & IH
https://www.readbyqxmd.com/read/28419276/molecular-features-of-the-v1-v4-coding-region-of-sexually-transmitted-human-immunodeficiency-virus-type-1
#19
Jun Yong Choi, Sergei L Kosakovsky Pond, Christy M Anderson, Douglas D Richman, Davey M Smith
Background.: Investigations into which human immunodeficiency virus type 1 (HIV-1) sequence features may be selected for transmission during sexual exposure have been hampered by the small number of characterized transmission pairs in individual studies. Methods.: To boost statistical power to detect differences in glycosylation, length, and electrical charge in the HIV-1 V1-V4 coding region, we reanalyzed all available 2485 env sequences derived from 114 subjects representing 58 transmission pairs from previous studies using mixed-effects linear regression and an approach to approximate the unobserved transmitted virus...
May 15, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28418987/the-roles-of-behavioral-and-social-science-research-in-the-fight-against-hiv-aids-a-functional-framework
#20
Paul Gaist, Michael J Stirratt
Landmark advances have been made in HIV/AIDS prevention and treatment. These include proof-of-concept and public health implementation of preexposure prophylaxis and "treatment as prevention" to reduce HIV transmission as well as definitive evidence of the clinical gain from early antiretroviral treatment initiation. Significant progress has been made in understanding and addressing the social contexts and behavioral factors that impact HIV prevention, care, and treatment interventions. These include facilitating uptake of testing and counseling, developing technology-based interventions that increase viral suppression, reducing HIV/AIDS-related stigma, and addressing other sociobehavioral and structural barriers to care and treatment...
August 1, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
keyword
keyword
56858
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"