keyword
MENU ▼
Read by QxMD icon Read
search

Biomedical hiv prevention

keyword
https://www.readbyqxmd.com/read/28419276/molecular-features-of-the-v1-v4-coding-region-of-sexually-transmitted-hiv-1
#1
Jun Yong Choi, Sergei L Kosakovsky Pond, Christy M Anderson, Douglas D Richman, Davey M Smith
Background: Investigations into which HIV-1 sequence features may be selected for transmission during sexual exposure have been hampered by the small number of characterized transmission pairs in individual studies. Methods: To boost statistical power to detect differences in glycosylation, length, and electrical charge in the HIV-1 V1-V4 coding region, we re-analyzed all available 2,485 env sequences derived from 114 subjects representing 58 transmission pairs from previous studies using mixed effects linear regression and an approach to approximate the unobserved transmitted virus...
April 17, 2017: Journal of Infectious Diseases
https://www.readbyqxmd.com/read/28418987/the-roles-of-behavioral-and-social-science-research-in-the-fight-against-hiv-aids-a-functional-framework
#2
Paul Gaist, Michael J Stirratt
Landmark advances have been made in HIV/AIDS prevention and treatment. These include proof-of-concept and public health implementation of pre-exposure prophylaxis (PrEP) and "treatment as prevention" (TasP) to reduce HIV transmission as well as definitive evidence of the clinical gain from early antiretroviral treatment (ART) initiation. Significant progress has been made in understanding and addressing the social contexts and behavioral factors that impact HIV prevention, care, and treatment interventions...
April 7, 2017: Journal of Acquired Immune Deficiency Syndromes: JAIDS
https://www.readbyqxmd.com/read/28418524/evaluating-testing-strategies-for-identifying-youths-with-hiv-infection-and-linking-youths-to-biomedical-and-other-prevention-services
#3
Robin Lin Miller, Cherrie B Boyer, Danielle Chiaramonte, Peter Lindeman, Kate Chutuape, Bendu Cooper-Walker, Bill G Kapogiannis, Craig M Wilson, J Dennis Fortenberry
Importance: Most human immunodeficiency virus (HIV)-infected youths are unaware of their serostatus (approximately 60%) and therefore not linked to HIV medical or prevention services. The need to identify promising and scalable approaches to promote uptake of HIV testing among youths at risk is critical. Objective: To evaluate a multisite HIV testing program designed to encourage localized HIV testing programs focused on self-identified sexual minority males and to link youths to appropriate prevention services after receipt of their test results...
April 17, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28415911/risk-safety-and-sex-among-male-prep-users-time-for-a-new-understanding
#4
Kimberly Koester, Rivet K Amico, Hailey Gilmore, Albert Liu, Vanessa McMahan, Kenneth Mayer, Sybil Hosek, Robert Grant
Recent advances in biomedical HIV prevention have led to optimistic projections of a dramatic worldwide reduction of new infections by 2030. This optimism is counterbalanced by concerns that the protective benefits of one such technology, HIV pre-exposure prophylaxis (PrEP), may be negated by increases in other behaviours that offset these benefits (risk compensation). To contribute to a deeper understanding of concepts of safety and risk in the context of HIV PrEP, we draw on the narrative accounts of 61 male PrEP users who participated in the inaugural PrEP demonstration project: the iPrEx open-label extension study...
April 18, 2017: Culture, Health & Sexuality
https://www.readbyqxmd.com/read/28406272/dorsal-longitudinal-foreskin-cut-is-associated-with-reduced-risk-of-hiv-syphilis-and-genital-herpes-in-men-a-cross-sectional-study-in-papua-new-guinea
#5
Andrew J Vallely, David MacLaren, Matthew David, Pamela Toliman, Angela Kelly-Hanku, Ben Toto, Rachael Tommbe, Zure Kombati, Petronia Kaima, Kelwyn Browne, Clement Manineng, Lalen Simeon, Claire Ryan, Handan Wand, Peter Hill, Greg Law, Peter M Siba, W John H McBride, John M Kaldor
INTRODUCTION: Various forms of penile foreskin cutting are practised in Papua New Guinea. In the context of an ecological association observed between HIV infection and the dorsal longitudinal foreskin cut, we undertook an investigation of this relationship at the individual level. METHODS: We conducted a cross-sectional study among men attending voluntary confidential HIV counselling and testing clinics. Following informed consent, participants had a face-to-face interview and an examination to categorize foreskin status...
April 3, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28338951/measuring-transitions-in-sexual-risk-among-men-who-have-sex-with-men-the-novel-use-of-latent-class-and-latent-transition-analysis-in-hiv-sentinel-surveillance
#6
Anna L Wilkinson, Carol El-Hayek, Christopher K Fairley, Norm Roth, B K Tee, Emma McBryde, Margaret Hellard, Mark Stoové
New combination human acquired deficiency (HIV) prevention strategies that include biomedical and primary prevention approaches add complexity to the task of measuring sexual risk. Latent transition models are beneficial for understanding complex phenomena; therefore, we trialed the application of latent class and latent transition models to HIV surveillance data. Our aims were to identify sexual risk states and model individuals' transitions between states. A total of 4,685 HIV-negative men who have sex with men (MSM) completed behavioral questionnaires alongside tests for HIV and sexually transmissible infections at one of 2 Melbourne, Victoria, Australia, general practices (2007-2013)...
April 15, 2017: American Journal of Epidemiology
https://www.readbyqxmd.com/read/28323441/breaking-binaries-biomedicine-and-serostatus-borderlands-among-couples-with-mixed-hiv-status
#7
Asha Persson, Christy E Newman, Jeanne Ellard
With recent breakthroughs in HIV treatment and prevention, the meanings of HIV-positivity and HIV-negativity are changing at biomedical and community levels. We explore how binary constructions of HIV serostatus identities are giving way to something more complex that brings both welcome possibilities and potential concerns. We draw on research with couples with mixed HIV status to argue that, in the context of lived experiences, serostatus identities have always been more ambiguous than allowed for in HIV discourse...
February 28, 2017: Medical Anthropology
https://www.readbyqxmd.com/read/28318310/comparison-of-maxim-and-sedia-limiting-antigen-assay-performance-for-measuring-hiv-incidence
#8
Katherine E Schlusser, Jacob Konikoff, Allison R Kirkpatrick, Charles Morrison, Tsungai Chipato, Pai-Lien Chen, Marshall Munjoma, Susan H Eshleman, Oliver Laeyendecker
Accurate methods for cross-sectional incidence estimation are needed for HIV prevention research. The Limiting Antigen Avidity (LAg-Avidity) assay has been marketed by two vendors, Maxim Biomedical and Sedia BioSciences Corporation. Performance differences between the two versions of the assay are unknown. We tested a total 1,410 treatment-naive samples with both versions of the assay. The samples came from 176 seroconverters from the Zimbabwe Hormonal Contraception and HIV Study. The correlation between the two versions of the assay was 0...
March 20, 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28274904/gender-specific-combination-hiv-prevention-for-youth-in-high-burden-settings-the-mp3-youth-observational-pilot-study-protocol
#9
Jasmine Buttolph, Irene Inwani, Kawango Agot, Charles M Cleland, Peter Cherutich, James N Kiarie, Alfred Osoti, Connie L Celum, Jared M Baeten, Ruth Nduati, John Kinuthia, Timothy B Hallett, Ramzi Alsallaq, Ann E Kurth
BACKGROUND: Nearly three decades into the epidemic, sub-Saharan Africa (SSA) remains the region most heavily affected by human immunodeficiency virus (HIV), with nearly 70% of the 34 million people living with HIV globally residing in the region. In SSA, female and male youth (15 to 24 years) are at a disproportionately high risk of HIV infection compared to adults. As such, there is a need to target HIV prevention strategies to youth and to tailor them to a gender-specific context. This protocol describes the process for the multi-staged approach in the design of the MP3 Youth pilot study, a gender-specific, combination, HIV prevention intervention for youth in Kenya...
March 8, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28271718/acceptability-of-microbicidal-vaginal-rings-and-oral-pre-exposure-prophylaxis-for-hiv-prevention-among-female-sex-workers-in-a-high-prevalence-us-city
#10
Sarah M Peitzmeier, Catherine Tomko, Erin Wingo, Anne Sawyer, Susan G Sherman, Nancy Glass, Chris Beyrer, Michele R Decker
Biomedical HIV prevention tools including oral pre-exposure prophylaxis (PrEP) and vaginal microbicidal rings hold unique value for high-risk women who may have limited capacity for condom negotiation, including the key populations of sex workers and drug users. Commercial sex is a PrEP indicator in CDC guidelines, yet little is known about female sex workers' (FSWs) knowledge of and attitudes toward PrEP or the recently developed monthly vaginal microbicide rings. We describe knowledge and attitudes toward PrEP and microbicide rings in a sample of 60 mostly drug-using FSWs in Baltimore, Maryland, a high HIV-prevalence US city...
March 8, 2017: AIDS Care
https://www.readbyqxmd.com/read/28249722/clinical-trials-and-systematic-reviews-addressing-similar-interventions-for-the-same-condition-do-not-consider-similar-outcomes-to-be-important-a-case-study-in-hiv-aids
#11
Ian J Saldanha, Tianjing Li, Cui Yang, Jill Owczarzak, Paula R Williamson, Kay Dickersin
BACKGROUND: The usefulness of clinical trials and systematic reviews is compromised when they report different outcomes. We compared outcomes in reviews of HIV/AIDS and the trials included in the reviews. STUDY DESIGN AND SETTING: We examined all Cochrane reviews of HIV/AIDS (as of June 2013) that included ≥1 trial, and the trials that the reviews included. We compared outcomes within subgroups defined by type of intervention: clinical management, biomedical prevention, behavioral prevention, and health services...
February 26, 2017: Journal of Clinical Epidemiology
https://www.readbyqxmd.com/read/28214391/correlates-of-willingness-to-initiate-pre-exposure-prophylaxis-and-anticipation-of-practicing-safer-drug-and-sex-related-behaviors-among-high-risk-drug-users-on-methadone-treatment
#12
Roman Shrestha, Pramila Karki, Frederick L Altice, Tania B Huedo-Medina, Jaimie P Meyer, Lynn Madden, Michael Copenhaver
BACKGROUND: Although people who use drugs (PWUD) are key populations recommended to receive pre-exposure prophylaxis (PrEP) to prevent HIV, few data are available to guide PrEP delivery in this underserved group. We therefore examined the willingness to initiate PrEP and the anticipation of HIV risk reduction while on PrEP among high-risk PWUD. METHODS: In a cross-sectional study of 400 HIV-negative, opioid dependent persons enrolled in a methadone program and reporting recent risk behaviors, we examined independent correlates of being willing to initiate PrEP...
April 1, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/28176168/a-global-estimate-of-the-acceptability-of-pre-exposure-prophylaxis-for-hiv-among-men-who-have-sex-with-men-a-systematic-review-and-meta-analysis
#13
Peng Peng, Shu Su, Christopher K Fairley, Minjie Chu, Shengyang Jiang, Xun Zhuang, Lei Zhang
Pre-exposure prophylaxis (PrEP) is a new biomedical intervention for HIV prevention. This study systematically reviews the acceptability of PrEP among men who have sex with men (MSM) worldwide. We searched major English databases to identify English-language articles published between July 2007 and July 2016, which reported the acceptability of PrEP and associated population characteristics. Meta-analysis was conducted to estimate a pooled acceptability, and meta-regression and subgroup analysis were used to analyse heterogeneities...
February 7, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28170304/hiv-pre-exposure-prophylaxis-and-postexposure-prophylaxis-in-japan-context-of-use-and-directions-for-future-research-and-action
#14
Anthony S DiStefano, Makiko Takeda
Biomedical HIV prevention strategies are playing an increasingly prominent role in addressing HIV epidemics globally, but little is known about their use in Japan, where persistent HIV disparities and a recently stable, but not declining, national epidemic indicate the need for evolving approaches. We conducted an ethnographic study to determine the context of pre-exposure prophylaxis (PrEP) and postexposure prophylaxis (PEP) use and to identify directions for future research and action in Japan. We used data from observational fieldwork in the Kansai region and Tokyo Metropolitan Area (n = 178 persons observed), qualitative interviews (n = 32), documents and web-based data sources (n = 321), and email correspondences (n = 9) in the period 2013-2016...
February 2017: AIDS Patient Care and STDs
https://www.readbyqxmd.com/read/28108878/stigma-and-conspiracy-beliefs-related-to-pre-exposure-prophylaxis-prep-and-interest-in-using-prep-among-black-and-white-men-and-transgender-women-who-have-sex-with-men
#15
Lisa A Eaton, Seth C Kalichman, Devon Price, Stephanie Finneran, Aerielle Allen, Jessica Maksut
The HIV/AIDS epidemic in the US continues to persist, in particular, among race, sexual orientation, and gender minority populations. Pre-exposure prophylaxis (PrEP), or using antiretroviral medications for HIV prevention, is an effective option, but uptake of PrEP has been slow. Sociocultural barriers to using PrEP have been largely underemphasized, yet have the potential to stall uptake and, therefore, warrant further understanding. In order to assess the relationships between potential barriers to PrEP (i...
January 20, 2017: AIDS and Behavior
https://www.readbyqxmd.com/read/28080947/hiv-testing-intervention-development-among-men-who-have-sex-with-men-in-the-developed-world
#16
Paul Flowers, Claudia Estcourt, Pam Sonnenberg, Fiona Burns
HIV testing is a 'gateway' technology, enabling access to treatment and HIV prevention. Biomedical approaches to prevention, such as pre-exposure prophylaxis and treatment as prevention, require accurate and regular HIV test results. HIV testing also represents a powerful 'teachable moment' for behavioural prevention. An increasing range of HIV tests and the emergence of self-managed diagnostic technologies (e.g. self-testing) means there is now considerable diversification of when, where and how results are available to those who test...
January 13, 2017: Sexual Health
https://www.readbyqxmd.com/read/28062389/internet-based-hiv-prevention-with-at-home-sexually-transmitted-infection-testing-for-young-men-having-sex-with-men-study-protocol-of-a-randomized-controlled-trial-of-keep-it-up-2-0
#17
Brian Mustanski, Krystal Madkins, George J Greene, Jeffrey T Parsons, Brent A Johnson, Patrick Sullivan, Michael Bass, Rebekah Abel
BACKGROUND: Human immunodeficiency virus (HIV) infections are increasing among young men who have sex with men (YMSM), yet few HIV prevention programs have studied this population. Keep It Up! (KIU!), an online HIV prevention program tailored to diverse YMSM, was developed to fill this gap. The KIU! 2.0 randomized controlled trial (RCT) was launched to establish intervention efficacy. OBJECTIVE: The objective of the KIU! study is to advance scientific knowledge of technology-based behavioral HIV prevention, as well as improve public health by establishing the efficacy of an innovative electronic health (eHealth) prevention program for ethnically and racially diverse YMSM...
January 7, 2017: JMIR Research Protocols
https://www.readbyqxmd.com/read/28027663/hiv-risk-inside-u-s-prisons-a-systematic-review-of-risk-reduction-interventions-conducted-in-u-s-prisons
#18
Pamela Valera, Yvonne Chang, Zi Lian
HIV prevalence in correctional populations is approximately five times that of the general adult population. This systematic review examines the broad question of HIV prevention and interventions to reduce inmate HIV-related risk behaviors in U.S. federal and state prisons. We conducted a systematic review of multiple databases and Google Scholar to identify behavioral, biomedical, social, and policy studies related to HIV among U.S. prison populations from 1980-2014. Studies were excluded if they did not focus on HIV, prison inmates, if they were conducted outside of the U...
December 27, 2016: AIDS Care
https://www.readbyqxmd.com/read/27993129/hepatitis-viruses-in-ethiopia-a-systematic-review-and-meta-analysis
#19
Yeshambel Belyhun, Melanie Maier, Andargachew Mulu, Ermias Diro, Uwe Gerd Liebert
BACKGROUND: The existing seroepidemiological data on viral hepatitis in Ethiopia showed a wide variation in prevalence pattern and the clinical and public health burden have been underestimated. The aim of this systematic review and meta-analysis was to provide a clear and comprehensive estimation of viral hepatitis epidemiology and the potential clinical burdens in Ethiopia. METHODS: A comprehensive literature search was carried out from five decades (1968-2015) published studies from biomedical databases; PubMed, Google scholar, Medline and Web of Science...
December 19, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27977386/stigma-gay-men-and-biomedical-prevention-the-challenges-and-opportunities-of-a-rapidly-changing-hiv-prevention-landscape
#20
Graham Brown, William Leonard, Anthony Lyons, Jennifer Power, Dirk Sander, William McColl, Ronald Johnson, Cary James, Matthew Hodson, Marina Carman
Improvements in biomedical technologies, combined with changing social attitudes to sexual minorities, provide new opportunities for HIV prevention among gay and other men who have sex with men (GMSM). The potential of these new biomedical technologies (biotechnologies) to reduce HIV transmission and the impact of HIV among GMSM will depend, in part, on the degree to which they challenge prejudicial attitudes, practices and stigma directed against gay men and people living with HIV (PLHIV). At the structural level, stigma regarding gay men and HIV can influence the scale-up of new biotechnologies and negatively affect GMSM's access to and use of these technologies...
December 16, 2016: Sexual Health
keyword
keyword
56858
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"