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Cannabis studies

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https://www.readbyqxmd.com/read/29045919/altered-attentional-control-strategies-but-spared-executive-functioning-in-chronic-cannabis-users
#1
Amy T Nusbaum, Paul Whitney, Carrie Cuttler, Alexander Spradlin, John M Hinson, Ryan J McLaughlin
BACKGROUND: Cannabis use has increased rapidly in recent decades. The increase in cannabis use makes it important to understand the potential influence of chronic use on attentional control and other executive functions (EFs). Because cannabis is often used to reduce stress, and because stress can constrain attentional control and EFs, the primary goal of this study was to determine the joint effect of acute stress and chronic cannabis use on specific EFs. METHODS: Thirty-nine cannabis users and 40 non-users were assigned to either a stress or no stress version of the Maastricht Acute Stress Test...
October 12, 2017: Drug and Alcohol Dependence
https://www.readbyqxmd.com/read/29045307/prevalence-of-antipsychotic-treated-patients-in-a-cohort-of-adult-addicted-patients
#2
Hélène Peyrière, Caroline Diot, Erika Nogue, Marie Verschave, Morgan Laure, Marie-Christine Picot, Pierre Petit, Hélène Donnadieu-Rigole, Yves Leglise
PURPOSE: The objective of this cross-sectional study was to describe and estimate the prevalence of antipsychotics (AP) in a cohort of addicted patients, and to compare the profiles of addictive patients receiving AP or not. METHODS: We included all adult patients seen at the addiction care center of Montpellier University Hospital, between January 1, 2015, and March 31, 2015. Demographic, clinical, and therapeutic data were collected from the patients' medical records...
October 17, 2017: Journal of Clinical Psychopharmacology
https://www.readbyqxmd.com/read/29044015/-argentina-enacts-first-law-on-medical-use-of-the-cannabis-plant-history-and-perspectives
#3
Eduardo L De Vito
In the last few years, great expectations have risen in the society concerning the eventual therapeutic usefulness of compounds derived from the cannabis plant. It is well known that these compounds are being used in treating certain health conditions, either through medical prescription or self-administration. Extreme opinions range from believing that it is a harmful and dangerous drug to sustaining that it is a panacea. However, the sheer existence of an endocannabinoid system in the brain compels us to study its dimensions and derivations thoroughly...
2017: Medicina
https://www.readbyqxmd.com/read/29038721/gender-differences-in-substance-use-patterns-and-disorders-among-an-iranian-patient-sample-receiving-methadone-maintenance-treatment
#4
Amir Ghaderi, Maryam Motmaen, Iraj Abdi, Morad Rasouli-Azad
BACKGROUND: The current prevalence rate of substance abuse and dependence, represents an increasing trend of substance abuse and dependence among women, and the results of epidemiology studies indicate that substance use patterns are different between men and women. This study aimed to determine gender differences in substance use patterns and disorders among the patients undergoing methadone maintenance treatment. METHODS: This cross-sectional study was conducted throughout a specified time bracket ranging from September 2012 through March 2013 in Methadone Maintenance Treatment (MMT) clinics of Mashhad, Iran...
September 2017: Electronic Physician
https://www.readbyqxmd.com/read/29034533/efficacy-tolerability-and-safety-of-cannabis-based-medicines-for-chronic-pain-management-an-overview-of-systematic-reviews
#5
REVIEW
W Häuser, F Petzke, M-A Fitzcharles
Medicinal cannabis has already entered mainstream medicine in some countries. This systematic review (SR) aimed at evaluating the efficacy, acceptability and safety of cannabis-based medicines for chronic pain management. Qualitative systematic review of SRs of randomized controlled trials with cannabis-based medicines for chronic pain management. The Cochrane databases of SRs, Database of Abstracts of Reviews of Effects and PubMed were searched for SR published in the period January 2009 to January 2017. Assessment of the methodological quality of SR was performed by the AMSTAR checklist...
October 15, 2017: European Journal of Pain: EJP
https://www.readbyqxmd.com/read/29034118/toward-a-patient-registry-for-cannabis-use-an-exploratory-study-of-patient-use-in-an-outpatient-health-care-clinic-in-oregon
#6
Kim A Hoffman, Javier Ponce Terashima, Dennis McCarty, John Muench
No abstract text is available yet for this article.
September 2017: World Medical & Health Policy
https://www.readbyqxmd.com/read/29031478/patterns-of-facial-trauma-before-and-after-legalization-of-marijuana-in-denver-colorado-a-joint-study-between-two-denver-hospitals
#7
Mofiyinfolu Sokoya, Justin Eagles, Tyler Okland, Dylan Coughlin, Hannah Dauber, Christopher Greenlee, Andrew A Winkler
INTRODUCTION: The effect of marijuana on human health has been studied extensively. Marijuana intoxication has been shown to affect performance, attention span, and reaction time. The public health relationship between trauma and cannabis use has also been studied, with mixed conclusions. In this report, the effect of marijuana legalization on many aspects of facial trauma at two hospitals in Denver, Colorado is examined. METHODS: A retrospective review of the electronic medical records was undertaken...
October 7, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29030980/beneficial-effect-of-alcohol-withdrawal-on-gut-permeability-and-microbial-translocation-in-patients-with-alcohol-use-disorder
#8
Hélène Donnadieu-Rigole, Nathalie Pansu, Thibault Mura, Stéphanie Pelletier, Régis Alarcon, Lucie Gamon, Pascal Perney, Florence Apparailly, Jean-Philippe Lavigne, Catherine Dunyach-Remy
BACKGROUND: The human intestinal microbiota exerts beneficial or harmful effects in several disorders. Many factors, including alcohol consumption, may influence its composition and trigger bacterial translocation. Excessive alcohol consumption increases gut permeability and translocation of endotoxin into peripheral circulation. Although plasma endotoxin concentrations have been measured often, quantitative changes following alcohol withdrawal have never been described in subjects with alcohol use disorder (AUD)...
October 14, 2017: Alcoholism, Clinical and Experimental Research
https://www.readbyqxmd.com/read/29028562/common-and-differential-factors-associated-with-abstinence-and-poly-drug-use-among-australian-adolescents
#9
Simone Pettigrew, Michelle Jongenelis, David Lawrence, Wavne Rikkers
BACKGROUND: Social norms relating to youth substance use are changing. In Australia, alcohol use among adolescents has fallen dramatically and tobacco and cannabis use have also reduced, albeit more moderately. The aim of the present study was to identify (i) factors associated with compliance with recommendations for zero intake of alcohol, tobacco, and cannabis and (ii) factors associated with poly drug use (intake of all three substances). METHODS: As part of the Young Minds Matter Study, a self-report survey was administered to 1661 Australian adolescents aged 15-17 years...
October 10, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29028489/assessment-of-types-of-synthetic-cannabinoids-in-narcotic-cases-assessed-by-the-council-of-forensic-medicine-between-2011-2015-ankara-turkey
#10
Ersin Göl, İsmet Çok
Synthetic cannabinoids mimic the effects of cannabis and are the largest and fastest growing class of newly appearing designer drugs. Reports have revealed that various types of synthetic cannabinoids are mixed with herbal substances. The present study investigated the herbal substance cases involving synthetic cannabinoids in Ankara and nearby cities in Turkey. Data were collected from the reports of synthetic cannabinoids that were analyzed between January 01, 2011 and December 31, 2015 in the Ankara Narcotic Department of the Council of Forensic Medicine at the request of the judicial authorities...
October 4, 2017: Forensic Science International
https://www.readbyqxmd.com/read/29025134/cannabis-dampens-the-effects-of-music-in-brain-regions-sensitive-to-reward-and-emotion
#11
Tom P Freeman, Rebecca A Pope, Matthew B Wall, James A Bisby, Maartje Luijten, Chandni Hindocha, Claire Mokrysz, Will Lawn, Abigail Moss, Michael A P Bloomfield, Celia J A Morgan, David J Nutt, H Valerie Curran
Background: Despite the current shift towards permissive cannabis policies, few studies have investigated the pleasurable effects users seek. Here we investigate the effects of cannabis on listening to music - a rewarding activity that frequently occurs in the context of recreational cannabis use. We additionally tested how these effects are influenced by cannabidiol (CBD), which may offset cannabis-related harms. Methods: Across three sessions, sixteen cannabis users inhaled cannabis with CBD, cannabis without CBD, and placebo...
September 2, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/29025078/a-cloud-on-the-horizon-a-survey-into-the-use-of-electronic-vaping-devices-for-recreational-drug-and-new-psychoactive-substance-nps-administration
#12
M S Blundell, P I Dargan, D M Wood
Background: There is limited published scientific data on vaping recreational drugs other than cannabis. A recent review suggested that 15% of people vaping cannabis have also vaped a synthetic cannabinoid receptor agonist (SCRA) and identified over 300 Internet reports of e-liquid manufacture of recreational drugs and/or new psychoactive substances (NPS). Aim: To determine the prevalence of use of electronic vaping devices for recreational drug and NPS delivery in the UK...
September 14, 2017: QJM: Monthly Journal of the Association of Physicians
https://www.readbyqxmd.com/read/29022873/adolescent-thc-exposure-in-female-rats-leads-to-cognitive-deficits-through-a-mechanism-involving-chromatin-modifications-in-the-prefrontal-cortex
#13
Pamela Prini, Franceso Rusconi, Erica Zamberletti, Marina Gabaglio, Federica Penna, Mauro Fasano, Elena Battaglioli, Daniela Parolaro, Tiziana Rubino
BACKGROUND: Increasing cannabis consumption among adolescents, studies that link its early use with mental illnesses, and the political debate on cannabis legalization together call for an urgent need to study molecular underpinnings of adolescent brain vulnerability. The emerging role of epigenetic mechanisms in psychiatric diseases led us to hypothesize that epigenetic alterations could play a role in causes and subsequent development of the depressive/psychotic-like phenotype induced by adolescent, but not adult, Δ9-tetrahydrocannabinol (THC) exposure in female rats...
October 12, 2017: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/29017688/cannabinoids-in-pain-management-and-palliative-medicine
#14
Winfried Häuser, Mary-Ann Fitzcharles, Lukas Radbruch, Frank Petzke
BACKGROUND: There are conflicting interpretations of the evidence regarding the efficacy, tolerability, and safety of cannabinoids in pain management and palliative medicine. METHODS: We conducted a systematic review (SR) of systematic reviews of randomized controlled trials (RCT) and prospective long-term observational studies of the use of cannabinoids in pain management and palliative medicine. Pertinent publications from January 2009 to January 2017 were retrieved by a selective search in the Cochrane Database of Systematic Reviews, the Database of Abstracts of Reviews of Effects, and Medline...
September 22, 2017: Deutsches Ärzteblatt International
https://www.readbyqxmd.com/read/28993073/the-use-of-cannabis-in-response-to-the-opioid-crisis-a-review-of-the-literature
#15
Marianne Beare Vyas, Virginia T LeBaron, Aaron M Gilson
BACKGROUND: A staggering number of Americans are dying from overdoses attributed to prescription opioid medications (POMs). In response, states are creating policies related to POM harm reduction strategies, overdose prevention, and alternative therapies for pain management, such as cannabis (medical marijuana). However, little is known about how the use of cannabis for pain management may be associated with POM use. PURPOSE: The purpose of this article is to examine state medical cannabis (MC) use laws and policies and their potential association with POM use and related harms...
September 21, 2017: Nursing Outlook
https://www.readbyqxmd.com/read/28991520/mortality-risk-in-a-sample-of-emergency-department-patients-who-use-cocaine-with-alcohol-and-or-cannabis
#16
Devin Gilmore, Jennifer Zorland, Joanna Akin, J Aaron Johnson, James G Emshoff, Gabriel P Kuperminc
BACKGROUND: Illicit drug use is common among Emergency Department (ED) patients, yet the association between drug use and subsequent mortality is not well understood. This study examines 36-month mortality rates for a sample of ED patients based on reported use of alcohol, cannabis, and cocaine both individually and in combination. METHODS: Patients (N = 1669) from two urban EDs were surveyed at the time of the visit. The patient survey included the Alcohol Smoking and Substance Involvement Screening Test (ASSIST) and information on physical and mental health, healthcare utilization, and risk factors associated with substance use...
October 9, 2017: Substance Abuse
https://www.readbyqxmd.com/read/28988545/a-controlled-trial-of-screening-brief-intervention-and-referral-for-treatment-sbirt-implementation-in-primary-care-in-the-united-arab-emirates
#17
Catriona Matheson, Christiane Pflanz-Sinclair, Amna Almarzouqi, Christine M Bond, Amanda J Lee, Anwar Batieha, H Al Ghaferi, A El Kashef
Aim This project evaluated the effectiveness of screening brief intervention and referral for treatment (SBIRT) in primary care in Abu Dhabi to manage patients with problematic substance use. This study aimed to determine whether: (i) training primary care physicians on the SBIRT model increased the identification of patients using substances at a harmful, hazardous or dependent level; (ii) training improved physicians' knowledge, attitudes and beliefs in self-efficacy in managing substance use. BACKGROUND: Substance use is increasing in the United Arab Emirates yet there has been no formal primary care intervention...
October 9, 2017: Primary Health Care Research & Development
https://www.readbyqxmd.com/read/28987070/impulsivity-predicts-poorer-improvement-in-quality-of-life-during-early-treatment-for-people-with-methamphetamine-dependence
#18
Adam J Rubenis, Rebecca E Fitzpatrick, Dan I Lubman, Antonio Verdejo-Garcia
BACKGROUND AND AIMS: Methamphetamine dependence is associated with heightened impulsivity and diminished quality of life, but the link between impulsivity and changes in quality of life during treatment has not been examined. We aimed to investigate how different elements of impulsivity predict change in quality of life in the six weeks after engaging in treatment. DESIGN: Longitudinal, observational cohort study. SETTING: Public and private detoxification and rehabilitation facilities in metropolitan Melbourne, Australia...
October 7, 2017: Addiction
https://www.readbyqxmd.com/read/28984055/daily-cannabis-and-reduced-risk-of-steatosis-in-human-immunodeficiency-virus-and-hepatitis-c-virus-co-infected-patients-anrs-co13-hepavih
#19
Sandra Nordmann, Antoine Vilotitch, Perrine Roux, Laure Esterle, Bruno Spire, Fabienne Marcellin, Dominique Salmon-Ceron, François Dabis, Julie Chas, David Rey, Linda Wittkop, Philippe Sogni, Patrizia Carrieri
Liver steatosis is common in Human Immunodeficiency Virus (HIV) - Hepatitis C Virus (HCV) co-infected patients. Some recent studies have found that cannabis use is negatively associated with insulin resistance in the general population and in HIV-HCV co-infected patients. Given the causal link between insulin resistance and steatosis, we hypothesized that cannabis use has a positive impact on steatosis. Therefore, we aimed to study whether cannabis use in this population was associated with a reduced risk of steatosis, measured by ultrasound examination...
October 6, 2017: Journal of Viral Hepatitis
https://www.readbyqxmd.com/read/28983880/cannabis-and-cannabinoids-for-chronic-pain
#20
REVIEW
E Alfonso Romero-Sandoval, Ashley L Kolano, P Abigail Alvarado-Vázquez
PURPOSE OF REVIEW: The purpose of this study was to provide the most up-to-date scientific evidence of the potential analgesic effects, or lack thereof, of the marijuana plant (cannabis) or cannabinoids, and of safety or tolerability of their long-term use. RECENT FINDINGS: We found that inhaled (smoked or vaporized) cannabis is consistently effective in reducing chronic non-cancer pain. Oral cannabinoids seem to improve some aspects of chronic pain (sleep and general quality of life), or cancer chronic pain, but they do not seem effective in acute postoperative pain, abdominal chronic pain, or rheumatoid pain...
October 5, 2017: Current Rheumatology Reports
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