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Platelet-rich fibrin

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https://www.readbyqxmd.com/read/28093367/effect-of-construction-of-tio2-nanotubes-on-platelet-behaviors-structure-property-relationships
#1
Qiaoling Huang, Yun Yang, Dajiang Zheng, Ran Song, Yanmei Zhang, Pinliang Jiang, Erwin A Vogler, Changjian Lin
: Blood compatibility of TiO2 nanotubes (TNTs) has been assessed in rabbit platelet-rich plasma (PRP), which combines activation of both blood plasma coagulation and platelets. We find that (i) amorphous TiO2 nanotubes (TNTs) with relatively larger outer diameters led to reduced platelet adhesion/activation, (ii) TNTs with relatively smaller outer diameters in a predominately rutile phase also inhibited platelet adhesion and activation, and (iii) a pervasive fibrin network formed on larger outer diameter TNTs in a predominately anatase phase...
January 13, 2017: Acta Biomaterialia
https://www.readbyqxmd.com/read/28093204/chin-symphysis-bone-allograft-and-platelet-rich-fibrin-is-the-combination-effective-in-repair-of-alveolar-cleft
#2
Bijan Movahedian Attar, Navid Naghdi, Milad Etemadi Sh, Mojdeh Mehdizadeh
PURPOSE: Secondary grafting of alveolar defects with iliac crest bone is a common treatment method in cleft patients. The aim of this study was to evaluate the effectiveness of the combination of symphysis bone, allograft, and platelet-rich fibrin in regeneration of alveolar defects compared with iliac bone graft. MATERIALS AND METHODS: In this randomized clinical trial, patients with unilateral alveolar defects were divided randomly into two categories. Group A comprised patients in whom the combination of chin symphysis bone plus allogeneic bone material plus leukocyte- and platelet-rich fibrin was considered for treatment...
December 26, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28072995/-the-effects-of-platelet-rich-fibrin-extract-on-mc3t3-e1-cells-cultured-on-the-titanium-discs
#3
X J Zhang, S Xu, W Y Meng, H J Xiao, K Dong, Z H Liu
Objective: To evaluate the effect of platelet-rich fibrin extract (PRFe) on the adhesion, proliferation and differentiation of MC3T3-E1 cells cultured on the titanium discs. Methods: Samples were divided into experimental group (P) and control group (D). Group P used the α-minimal essential medium (α-MEM) containing PRFe (0.5%), while group D used only the α-MEM. Cell adhesion and cytoskeleton were observed using scanning electron microscopy (SEM) and laser scanning confocal microscopy (LSCM). Methyl thiazolyl tetrazolium (MTT) assay to detect the number of the osteoblasts at 1, 3, 5, 7 d; the activity of alkaline phosphatase (ALP) to detect the differentiation of osteoblast at 1, 3, 5, 7 d; the level of osteogenetic biomarkers core-binding factorα1 (cbfα1) and osteocalcin (OCN) were quantified by quantitative real-time PCR (qRT-PCR) at 3 and 7 d...
January 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28050518/revitalization-of-an-immature-permanent-mandibular-molar-with-a-necrotic-pulp-using-platelet-rich-fibrin-a-case-report
#4
Dayalan Subash, Krishnamma Shoba, Shibu Aman, Srinivasan Kumar Indu Bharkavi
Any insult to the pulp during its development causes cessation of dentin formation and root growth. Pulpal status and degree of root development are the decisive factors in the treatment approach. Various treatment options have been tried like surgery with root-end sealing, calcium hydroxide-apexification, placement of apical plug and regenerative endodontic procedures to induce apexogenesis. An ideal scenario for a necrosed tooth with immature root would be continued root development coupled with regeneration of pulp tissue...
November 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/28042979/does-the-addition-of-bone-morphogenetic-protein-2-to-platelet-rich-fibrin-improve-healing-after-treatment-for-medication-related-osteonecrosis-of-the-jaw
#5
Jung-Hyun Park, Jin-Woo Kim, Sun-Jong Kim
PURPOSE: To investigate the effect of the addition of bone morphogenetic protein 2 (BMP-2) to leukocyte-rich and platelet-rich fibrin (L-PRF) on the treatment of medication-related osteonecrosis of the jaws (MRONJ), this study compared the healing outcome of combined use of BMP-2 and L-PRF with single use of L-PRF. PATIENTS AND METHODS: Of 55 patients who were diagnosed with MRONJ, 25 were treated with L-PRF alone and 30 were treated with L-PRF and recombinant human BMP-2...
December 11, 2016: Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28042265/comparative-evaluation-of-platelet-rich-fibrin-versus-beta-tri-calcium-phosphate-in-the-treatment-of-grade-ii-mandibular-furcation-defects-using-cone-beam-computed-tomography
#6
Zeba Rahman Siddiqui, Rajesh Jhingran, Vivek Kumar Bains, Ruchi Srivastava, Rohit Madan, Iram Rizvi
OBJECTIVE: The objective of the study was to evaluate clinically and radiographically the efficacy of platelet-rich fibrin (PRF) versus β-tri-calcium phosphate (β-TCP) in the treatment of Grade II mandibular furcation defects. MATERIALS AND METHODS: Forty-five Grade II furcation defect in mandibular molars which were assigned to open flap debridement (OFD) with PRF Group I (n = 15), to OFD with β-TCP Group II (n = 15), and to OFD alone Group III (n = 15) were analyzed for clinical parameters (probing pocket depth [PPD], vertical clinical attachment level [VCAL], horizontal clinical attachment level [HCAL], gingival recession, relative vertical height of furcation [r-VHF], and relative horizontal depth of furcation [r-HDF]) and radiographical parameters (horizontal depth of furcation [H-DOF], vertical height of furcation [V-HOF]) using cone-beam computed tomography (CBCT) at 6 months interval...
October 2016: European Journal of Dentistry
https://www.readbyqxmd.com/read/28005755/management-of-zygomatic-fractures-in-young-patients-technical-modifications-for-aesthetic-and-functional-results
#7
Antonio Cortese, Giuseppe D'Alessio, Sergio Brongo, Maurizio Gargiulo, Pier Paolo Claudio
INTRODUCTION: The zygomaticomaxillary complex is very vulnerable to injury because of its intrinsically prominent convexity. There are 2 different surgical approaches for the therapy of these fractures: closed reduction and open reduction. In the open reduction 2 or 3 fixation points with related incisions are usually necessary in dislocated fractures: osteosynthesis must be performed starting from zygomaticofrontal suture when dislocated at this site, followed by zygomatic body fixation on the anterior sinus wall, anterior orbital floor margin fixation, and finally orbital floor reconstruction in case of eye globe dislocation with diplopia...
November 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28002899/intraoperative-application-platelet-rich-fibrin-postoperative-injections-of-prp-or-microfracture-only-for-osteochondral-lesions-of-the-knee-a-five-year-retrospective-evaluation
#8
R Papalia, L Diaz Balzani, G Torre, M C Tirindelli, C Nobile, N Maffulli, V Denaro
Cartilage lesions are the most common cause of chronic knee pain. Micro-fracturing is reliable, effective, easy to perform and inexpensive. We propose a novel approach to cartilage lesions where microfractures are performed contextually to intra-operative or post-operative administration of platelet concentrates. We retrospectively evaluate 48 patients divided in 3 groups. Group 1: 15 patients underwent microfractures and intraoperative administration of PRF (PRF group); group 2: 16 microfractures and postoperative injections of PRP (PRP group); group 3: 17 patients with isolated microfractures (Microfractures group)...
October 2016: Journal of Biological Regulators and Homeostatic Agents
https://www.readbyqxmd.com/read/27994892/natural-tooth-pontic-an-instant-esthetic-option-for-periodontally-compromised-teeth-a-case-series
#9
Rishi Raj, Kriti Mehrotra, Ipshita Narayan, Triveni Mavinakote Gowda, D S Mehta
Sudden tooth loss in the esthetic zone of the maxillary or mandibular anterior region can be due to trauma, periodontal disease, or endodontic failure. The treatment options for replacing the missing tooth can vary between removable prosthesis, tooth-supported prosthesis, and implant-supported prosthesis. Irrespective of the final treatment, the first line of management would be to provisionally restore the patient's esthetic appearance at the earliest, while functionally stabilizing the compromised arch. Using the patient's own natural tooth as a pontic offers the benefits of being the right size, shape, and color and provides exact repositioning in its original intraoral three-dimensional position...
2016: Case Reports in Dentistry
https://www.readbyqxmd.com/read/27994420/comparative-evaluation-of-platelet-rich-fibrin-mineral-trioxide-aggregate-and-calcium-hydroxide-as-pulpotomy-agents-in-permanent-molars-with-irreversible-pulpitis-a-randomized-controlled-trial
#10
Varun Kumar, Ruchi Juneja, Jigyasa Duhan, Pankaj Sangwan, Sanjay Tewari
BACKGROUND: Pulpotomy has been proposed as an alternative for the management of irreversible pulpitis in permanent molars with closed apices. AIM: To compare the performances of calcium hydroxide (CH), mineral trioxide aggregate (MTA), and platelet-rich fibrin (PRF) as pulpotomy agents in mature permanent molars with irreversible pulpitis. MATERIALS AND METHODS: Fifty-four permanent mandibular molars with carious exposure and symptoms of irreversible pulpitis were randomly allocated to three groups, and full pulpotomy was performed using CH, MTA, or PRF as pulpotomy agents...
October 2016: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/27987720/fabrication-and-characterization-of-platelet-rich-plasma-scaffolds-for-tissue-engineering-applications
#11
Mahmoud Sadeghi-Ataabadi, Zohreh Mostafavi-Pour, Zahra Vojdani, Mahsa Sani, Mona Latifi, Tahereh Talaei-Khozani
Platelet-Rich Plasma (PRP), as a rich source of growth factor, can form a fibrin gel that recapitulates the extracellular matrix of the tissues. The aim of this study was to evaluate the effects of different concentrations of CaCl2 on the PRP scaffold structure which in turn could change the cell's behavior. PRP was mixed with 2.5, 5 and 10% (w/v) CaCl2. Then, the tensile strength, biodegradability and water content of the scaffolds were evaluated. We also performed immunostaining for assessment of the actin stress fiber orientation and SEM for detecting the cell phenotype and physical properties of the fibers...
February 1, 2017: Materials Science & Engineering. C, Materials for Biological Applications
https://www.readbyqxmd.com/read/27966508/comparative-evaluation-of-platelet-rich-fibrin-and-autogenous-bone-graft-for-the-treatment-of-infrabony-defects-in-chronic-periodontitis-clinical-radiological-and-surgical-reentry
#12
Sneha Galav, Kabbur Thippanna Chandrashekar, Rohit Mishra, Vandana Tripathi, Richa Agarwal, Ankit Galav
CONTEXT: Both intraoral autogenous bone grafting (ABG) and platelet-rich fibrin (PRF) offer a useful treatment modality for periodontal regeneration of intrabony defects (IBDs). However, predictable regeneration in patients with severe attachment loss is a challenge to the practitioners. AIM: The aim of this study was to compare the clinical efficacy of PRF with ABG for the treatment of IBDs in chronic periodontitis. SETTINGS AND DESIGN: This is a randomized controlled trial...
September 2016: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/27941590/traumatic-hemothorax-blood-contains-elevated-levels-of-microparticles-that-are-prothrombotic-but-inhibit-platelet-aggregation
#13
Thomas A Mitchell, Maryanne C Herzig, Chriselda G Fedyk, Marc A Salhanick, Aaron T Henderson, Bijaya K Parida, Nicolas J Prat, Daniel L Dent, Martin G Schwacha, Andrew P Cap
OBJECTIVES: Autotransfusion of shed blood from traumatic hemothorax is an attractive option for resuscitation of trauma patients in austere environments. However, previous analyses revealed that shed hemothorax (HX) blood is defibrinated, thrombocytopenic, and contains elevated levels of D-dimer. Mixing studies with normal pooled plasma demonstrated hypercoagulability, evoking concern for potentiation of acute traumatic coagulopathy. We hypothesized that induction of coagulopathic changes by shed HX blood may be due to increases in cellular microparticles (MP) and that these may also affect recipient platelet function...
December 9, 2016: Shock
https://www.readbyqxmd.com/read/27915981/molecular-cellular-and-pharmaceutical-aspects-of-autologous-grafts-for-peri-implant-hard-and-soft-tissue-defects
#14
Jiayu Lu, Yongming Hao, Wei Zhao, Chengqi Lv, Derong Zou
The lack of supporting hard and soft tissues always prevents the rehabilitation with dental implants. Among various hard and soft tissue augmentation procedures, autologous grafts have been considered to be the gold standard. Autologous mesenchymal stem cells (MSCs) from bone marrow, dental tissue and adipose tissue have been described as promising alternatives for bone regeneration in the field of dental implantation. Mucosal cells, gingival fibroblasts and dental progenitor cells (DPS) can enhance peri-implant soft tissue augmentation and regenerate periodontal tissues around dental implants...
December 1, 2016: Current Pharmaceutical Biotechnology
https://www.readbyqxmd.com/read/27900247/use-of-autologous-platelet-rich-fibrin-in-osseous-regeneration-after-cystic-enucleation-a-clinical-study
#15
Manzoor Dar, Tajamul Hakim, Ajaz Shah, Latief Najar, Gowhar Yaqoob, Faiqah Lanker
AIMS AND OBJECTIVES: The aim of this study was to evaluate the efficacy of PRF in osseous regeneration after enucleation of cystic lesions. The objectives of this study were as follows: (1) to evaluate osseous regeneration radiographically with the use of PRF in intrabony defects after cystic enucleation. (2) To evaluate the degree of bone density in intrabony defects with the use of PRF postoperatively after 1st, 3rd, and 6th months. SUBJECTS AND METHODS: 20 cases of cystic lesions were treated using PRF after cystic enucleation...
November 2016: Journal of Oral Biology and Craniofacial Research
https://www.readbyqxmd.com/read/27891638/regenerative-potential-of-leucocyte-and-platelet-rich-fibrin-l-prf-part-b-sinus-floor-elevation-alveolar-ridge-preservation-and-implant-therapy-a-systematic-review
#16
REVIEW
Ana B Castro, Nastaran Meschi, Andy Temmerman, Nelson Pinto, Paul Lambrechts, Wim Teughels, Marc Quirynen
AIM: To analyse the effect of Leucocyte- and Platelet Rich Fibrin (L-PRF) on bone regeneration procedures and osseointegration. MATERIALS AND METHODS: An electronic and hand search was conducted in three databases (MEDLINE, EMBASE and Cochrane). Only randomised clinical trials, written in English where L-PRF was applied in bone regeneration and implant procedures, were selected. No follow-up restrictions were applied. RESULTS: A total of 14 articles were included and processed...
November 28, 2016: Journal of Clinical Periodontology
https://www.readbyqxmd.com/read/27875512/single-tooth-osteotomy-combined-wide-linear-corticotomy-under-local-anesthesia-for-correcting-anterior-protrusion-with-ectopically-erupted-canine
#17
Nur Serife Iskenderoglu, Byung-Joon Choi, Kyung Won Seo, Yeon-Ji Lee, Baek-Soo Lee, Seong-Hun Kim
BACKGROUNDS: This article presents the alternative surgical treatments of both anterior protrusion by carrying out retraction on mandibular anterior fragment, meanwhile applying retraction force on maxilla anterior teeth and ectopically erupted canine with using platelet-rich fibrin (PRF). METHODS: Anterior segmental osteotomy was combined with linear corticotomy under local anesthesia. The correction of right ectopic canine was achieved through 2 stages. First, dento-osseous osteotomy on palatal side was performed...
November 21, 2016: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/27857762/scaffolds-in-regenerative-endodontics-a-review
#18
REVIEW
Kinjal M Gathani, Srinidhi Surya Raghavendra
Root canal therapy has enabled us to save numerous teeth over the years. The most desired outcome of endodontic treatment would be when diseased or nonvital pulp is replaced with healthy pulp tissue that would revitalize the teeth through regenerative endodontics. 'A search was conducted using the Pubmed and MEDLINE databases for articles with the criteria 'Platelet rich plasma', 'Platelet rich fibrin', 'Stem cells', 'Natural and artificial scaffolds' from 1982-2015'. Tissues are organized as three-dimensional structures, and appropriate scaffolding is necessary to provide a spatially correct position of cell location and regulate differentiation, proliferation, or metabolism of the stem cells...
September 2016: Dental Research Journal
https://www.readbyqxmd.com/read/27853485/study-on-the-efficacy-of-platelet-rich-fibrin-matrix-in-hair-follicular-unit-transplantation-in-androgenetic-alopecia-patients
#19
Sandeep Mahapatra, Dhruva Kumar, Vignesh Subramanian, Swarup K Chakrabarti, Kaushik D Deb
Objective: Hair loss is a significant problem worldwide. The most common cause of hair loss in men is male androgenetic alopecia, male pattern baldness, which is primarily due to the presence of nonfunctional or dead hair follicles in the scalp. Hair follicular unit transplantation has been a widely used technique to transplant hair follicles into bald areas. Although follicular unit transplantation generally gives satisfactory hair transplantation, efforts have been made to further increase the efficacy of follicular unit transplantation in hair regeneration...
September 2016: Journal of Clinical and Aesthetic Dermatology
https://www.readbyqxmd.com/read/27853331/effects-of-platelet-rich-plasma-platelet-rich-fibrin-with-and-without-stromal-cell-derived-factor-1-on-repairing-full-thickness-cartilage-defects-in-knees-of-rabbits
#20
Soghra Bahmanpour, Maryam Ghasemi, Mohsen Sadeghi-Naini, Iraj Ragerdi Kashani
BACKGROUND: The purpose of this study was to create biomaterial scaffolds like platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) containing stromal cell-derived factor-1 (SDF1) as a chemokine to induce hyaline cartilage regeneration of rabbit knee in a full thickness defect. METHODS: We created a full thickness defect in the trochlear groove of thirty-six bilateral knees of eighteen mature male rabbits. The knees were randomly divided into six groups (group I: untreated control, group II: PRP, group III: PRF, group IV: Gelatin+SDF1, group V: PRP+SDF1, and group VI: PRF+SDF1)...
November 2016: Iranian Journal of Medical Sciences
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