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Platelet-rich fibrin

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https://www.readbyqxmd.com/read/28529414/comparison-of-efficacy-of-autologous-platelet-rich-fibrin-versus-saline-dressing-in-chronic-venous-leg-ulcers-a-randomised-controlled-trial
#1
Anirudh Somani, Reena Rai
BACKGROUND: Venous leg ulcer is a chronic condition, and various treatment modalities are available. Platelet-rich fibrin (PRF) is one of the newer modalities and it contains fibroblast growth factor (GF), vascular endothelial GF, angiopoitin and platelet-derived GF which enhances the wound healing. Hence, we conducted a randomised controlled trial to compare the efficacy of PRF versus saline dressing in chronic venous leg ulcers. AIM: This study aims to compare the efficacy of autologous PRF with saline dressing in patients with chronic venous leg ulcer and to compare the mean reduction in ulcer area at the end of 4 weeks...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28529413/autologous-platelet-rich-fibrin-matrix-in-non-healing-trophic-ulcers-in-patients-with-hansen-s-disease
#2
Umashankar Nagaraju, Priya K Sundar, Priyanka Agarwal, Belliappa P Raju, Mahesh Kumar
BACKGROUND: Non-healing trophic ulcers in Hansen's disease patients is one of the major causes for disability. It has been shown that autologous platelet-rich fibrin matrix (PRFM) is effective in healing chronic non-healing leg ulcers. AIM: The objective of this study is to demonstrate the efficacy of autologous platelet-rich fibrin matrix (PRFM) in non-healing trophic ulcers in patients treated for Hansen's disease. DESIGN: A prospective study...
January 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/28523446/in-vitro-quantification-of-luminal-denudation-after-crimping-and-balloon-dilatation-of-endothelialized-covered-stents
#3
Shigeo Ichihashi, Frederic Wolf, Thomas Schmitz-Rode, Kimihiko Kichikawa, Stefan Jockenhoevel, Petra Mela
PURPOSE: Covered stents have been demonstrated to reduce restenosis; however, the membrane's limited biocompatibility can still lead to thrombus formation. To obtain optimal surface hemocompatibility, endothelialization of the luminal surface has been proposed. However, the effect of delivery procedures, such as crimping and balloon dilatation, on the endothelial layer has not been quantified. This study investigated the impact of such procedures on endothelialized covered stents in vitro...
May 18, 2017: Cardiovascular and Interventional Radiology
https://www.readbyqxmd.com/read/28518182/triple-layered-closure-of-an-oroantral-fistula-a-case-report
#4
Eric George
Oroantral fistulae (OAF) are surgical sequelae that require complete resection and often leave large defects for the surgeon to repair. Closing these lesions is often technique sensitive and requires a detailed protocol, which, if not adhered to, can lead to recurrence. This case report presents a combined approach to closing an OAF by first excising the fistula and then resecting to retrieve the buccal fat pad to form a pedicle graft over the wound site. Next, a platelet-rich fibrin membrane is sandwiched over the buccal fat pad and completely covered by a buccal advancement flap...
May 18, 2017: International Journal of Oral & Maxillofacial Implants
https://www.readbyqxmd.com/read/28509340/prf-based-matrices-to-improve-angiogenesis-in-an-in-vitro-co-culture-model-for-bone-tissue-engineering
#5
Eva Dohle, Karima El Bagdadi, Robert Sader, Joseph Choukroun, C James Kirkpatrick, Shahram Ghanaati
In the context of prevascularization strategies for tissue engineering purposes, co-culture systems consisting of outgrowth endothelial cells (OECs) and primary osteoblasts (pOBs) have been established as a promising in vitro tool to study regeneration mechanisms and to identify factors that might positively influence repair processes like wound healing or angiogenesis. The development of autologous injectable platelet rich fibrin (PRF), which can be generated from peripheral blood in a minimal invasive procedure, fulfils several requirements for clinically applicable cell-based tissue engineering strategies...
May 16, 2017: Journal of Tissue Engineering and Regenerative Medicine
https://www.readbyqxmd.com/read/28498077/the-effect-of-platelet-rich-fibrin-membrane-on-the-repair-of-perforated-tympanic-membrane-an-experimental-study
#6
Nuray Ensari, Özer Erdem Gür, Mehmet Türker Öztürk, Dinç Süren, Ömer Tarık Selçuk, Üstün Osma
CONCLUSION: Platelet-rich fibrin (PRF) membrane could be used successfully in the repair of tympanic membrane perforation and wound healing. OBJECTIVES: To evaluate the effect of platelet-rich fibrin membrane in the repair of perforated tympanic membrane. METHODS: After otoscopic examination, a 3-mm perforation was made in the posterior quadrant of both tympanic membranes of 50 adult male Sprague-Dawley rats. Venous blood was withdrawn from the rats, then centrifuged...
February 22, 2017: Acta Oto-laryngologica
https://www.readbyqxmd.com/read/28489660/effects-of-growth-factors-from-platelet-rich-fibrin-on-the-bone-regeneration
#7
Jin Kim, Yooseok Ha, Nak Heon Kang
Platelet-rich fibrin (PRF) has simple manufacturing process without risk of immunologic rejection or infection by additional materials. This study was designed to investigate the effects of platelet-derived growth factors and transforming growth factors-β in PRF on the proliferation and differentiation of osteoblasts. The authors analyzed platelet-derived growth factors and transforming growth factors-β in normal human serum (NHS) and PRF by enzyme-linked immunosorbent assay quantitatively and those in PRF group were significantly increased when compared with NHS...
May 9, 2017: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/28482449/-platelet-rich-fibrin-in-the-treatment-of-narrow-keratinized-mucosa-a-case-report
#8
Z Z Liu, Y M Zhou, X L Sun, Y Guo, T Q Guo
No abstract text is available yet for this article.
May 9, 2017: Zhonghua Kou Qiang Yi Xue za Zhi, Zhonghua Kouqiang Yixue Zazhi, Chinese Journal of Stomatology
https://www.readbyqxmd.com/read/28476390/achilles-tendon-open-surgical-treatment-with-platelet-rich-fibrin-matrix-augmentation-biomechanical-evaluation
#9
Federica Alviti, Michele Gurzì, Valter Santilli, Marco Paoloni, Roberto Padua, Andrea Bernetti, Marco Bernardi, Massimiliano Mangone
The relationship between surgical technique and ankle biomechanical properties after surgery for acute rupture of the Achilles tendon (ATR) has not yet been fully investigated. Platelet-rich fibrin (PRF) matrices seem to play a central role in the complex processes of tendon healing. Our aim was to analyze the biomechanical characteristics, stiffness, and mechanical work of the ankle during walking in patients who had undergone surgery after ATR with and without PRF augmentation. We performed a retrospective review of all consecutive patients who had been treated with surgical repair after ATR...
May 2017: Journal of Foot and Ankle Surgery: Official Publication of the American College of Foot and Ankle Surgeons
https://www.readbyqxmd.com/read/28473242/evaluation-of-postoperative-complications-after-mandibular-third-molar-surgery-with-the-use-of-platelet-rich-fibrin-a-systematic-review-and-meta-analysis
#10
REVIEW
J V Dos S Canellas, F G Ritto, P J D Medeiros
The current literature was reviewed to analyze the effects of platelet-rich fibrin (PRF) on postoperative complications after mandibular third molar surgery (pain, alveolar osteitis, swelling, and bone healing). A comprehensive literature search was performed up to 2016 in the PubMed/MEDLINE, Cochrane Library, LILACS, and ScienceDirect databases and the grey literature. Additional records were identified through manual and reference searches. The full-text articles of potentially relevant studies were reviewed; only randomized clinical trials were included...
May 1, 2017: International Journal of Oral and Maxillofacial Surgery
https://www.readbyqxmd.com/read/28466249/mechanical-and-degradation-properties-of-advanced-platelet-rich-fibrin-a-prf-concentrated-growth-factors-cgf-and-platelet-poor-plasma-derived-fibrin-pptf
#11
Kazushige Isobe, Taisuke Watanebe, Hideo Kawabata, Yutaka Kitamura, Toshimitsu Okudera, Hajime Okudera, Kohya Uematsu, Kazuhiro Okuda, Koh Nakata, Takaaki Tanaka, Tomoyuki Kawase
BACKGROUND: Fibrin clot membranes prepared from advanced platelet-rich fibrin (A-PRF) or concentrated growth factors (CGF), despite their relatively rapid biodegradability, have been used as bioactive barrier membranes for alveolar bone tissue regeneration. As the membranes degrade, it is thought that the growth factors are gradually released. However, the mechanical and degradable properties of these membranes have not well been characterized. The purpose of this study was to mechanically and chemically characterize these membranes...
December 2017: International Journal of Implant Dentistry
https://www.readbyqxmd.com/read/28458932/uncommon-odontogenic-orocutaneous-fistula-of-the-jaw-treated-with-platelet-rich-fibrin
#12
Kani Bilginaylar
Orocutaneous fistula (OCF) of dental origin is a relatively rare condition and continues to be a challenging diagnosis. Misdiagnosis of OCF usually leads to unnecessary and noneffective treatment. A 21-year-old male referred with a complaint of a lesion on the chin which was misdiagnosed as a carbuncle (lesion of nonodontogenic origin) by a physician. After radiological examination, there was a lesion around the apical region of right central incisor. These findings indicated a sinus tract associated with dental origin...
2017: Case Reports in Dentistry
https://www.readbyqxmd.com/read/28457420/atrophic-maxilla-reconstruction-with-fresh-frozen-allograft-bone-titanium-mesh-and-platelet-rich-fibrin-case-report
#13
R C F Baldan, F L Coracin, L Lins, W R Mello, P S Santos
The purpose of this article was to report the clinical and radiographic findings about a case of a man affected by severely atrophic maxilla to demonstrate the clinical proceedings associated with alveolar reconstruction destined for dental implant rehabilitation. The 3-dimensional augmentation of the alveolar ridge with the use of fresh-frozen bone graft, platelet-rich fibrin membrane, and titanium mesh suggests potential benefits to the development of the bone formation physiology. The treatment combination may result in an optimal prognosis and represents an option for reconstruction of bone defects...
May 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28452623/advantages-of-autologous-platelet-rich-fibrin-membrane-on-gingival-crevicular-fluid-growth-factor-levels-and-periodontal-healing-a-randomized-split-mouth-clinical-study
#14
Taner Arabaci, Oguz Kose, Mevlut Albayrak, Yasin Cicek, Alper Kizildag
AIM: To evaluate the contributions of platelet rich fibrin (PRF) combined with conventional flap surgery on the growth factor levels in gingival crevicular fluid (GCF) and periodontal healing. MATERIALS AND METHOD: 26 patients (52 sites) with chronic periodontitis were treated either with autologous PRF with open flap debridement (OFD+PRF) or open flap debridement (OFD) alone. Growth factor levels in GCF at baseline and 2, 4 and 6 weeks postoperatively were analyzed, and clinical parameters such as probing depth (PD), relative attachment level (RAL) and gingival margin level (GML) at baseline and 9 months after surgery were compromised...
April 28, 2017: Journal of Periodontology
https://www.readbyqxmd.com/read/28438151/effect-of-platelet-rich-fibrin-on-edema-and-pain-following-third-molar-surgery-a-split-mouth-control-study
#15
Uğur Gülşen, Mehmet Fatih Şentürk
BACKGROUND: To evaluate the efficacy of platelet-rich fibrine (PRF) on postoperative edema and pain after impacted mandibular third molar surgery. METHODS: The prospective study was comprised 30 patients who presented for the removal of bilateral impacted mandibular third molar teeth. After extraction, the sockets were filled with PRF or without PRF in the study and control groups, respectively. Postoperative edema was measured with a flexible tape measure by calculating the distance between several facial landmarks on postoperative days two and seven...
April 24, 2017: BMC Oral Health
https://www.readbyqxmd.com/read/28437133/the-impact-of-the-centrifuge-characteristics-and-centrifugation-protocols-on-the-cells-growth-factors-and-fibrin-architecture-of-a-leukocyte-and-platelet-rich-fibrin-l-prf-clot-and-membrane
#16
David M Dohan Ehrenfest, Nelson R Pinto, Andrea Pereda, Paula Jiménez, Marco Del Corso, Byung-Soo Kang, Mauricio Nally, Nicole Lanata, Hom-Lay Wang, Marc Quirynen
L-PRF (leukocyte- and platelet-rich fibrin) is one of the four families of platelet concentrates for surgical use and is widely used in oral and maxillofacial regenerative therapies. The first objective of this article was to evaluate the mechanical vibrations appearing during centrifugation in four models of commercially available table-top centrifuges used to produce L-PRF and the impact of the centrifuge characteristics on the cell and fibrin architecture of a L-PRF clot and membrane. The second objective of this article was to evaluate how changing some parameters of the L-PRF protocol may influence its biological signature, independently from the characteristics of the centrifuge...
April 24, 2017: Platelets
https://www.readbyqxmd.com/read/28401929/the-effect-of-l-prf-membranes-on-bone-healing-in-rabbit-tibiae-bone-defects-micro-ct-and-biomarker-results
#17
Fernanda Faot, Sanne Deprez, Katleen Vandamme, Germana V Camargos, Nelson Pinto, Jasper Wouters, Joost van den Oord, Marc Quirynen, Joke Duyck
More insight into the biological fundamentals of leukocyte platelet-rich fibrin (L-PRF) guided healing is necessary to recommend its application, in particular in deficient bone sites that need to support implants. This study investigated the short-term bone healing effect of L-PRF treatment in cylindrical non-critical sized bone defects with 3 mm diameter and 6 mm depth in tibiae of 18 adult male New Zealand White rabbits. After a randomization process, 96 bone defects were prepared and half of them were filled with a L-PRF membrane, while untreated defects in the opposite tibia served as control group...
April 12, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28401197/platelet-rich-fibrin-prf-in-implants-dentistry-in-combination-with-new-bone-regenerative-flapless-technique-evolution-of-the-technique-and-final-results
#18
Antonio Cortese, Giuseppe Pantaleo, Massimo Amato, Candace M Howard, Lorenzo Pedicini, Pier Paolo Claudio
Most common techniques for alveolar bone augmentation are guided bone regeneration (GBR) and autologous bone grafting. GBR studies demonstrated long-term reabsorption using heterologous bone graft. A general consensus has been achieved in implant surgery for a minimal amount of 2 mm of healthy bone around the implant. A current height loss of about 3-4 mm will result in proper deeper implant insertion when alveolar bone expansion is not planned because of the dome shape of the alveolar crest. To manage this situation a split crest technique has been proposed for alveolar bone expansion and the implants' insertion in one stage surgery...
January 2017: Open Medicine (Warsaw, Poland)
https://www.readbyqxmd.com/read/28393825/a-contemporary-approach-for-treatment-planning-of-horizontally-resorbed-alveolar-ridge-ridge-split-technique-with-simultaneous-implant-placement-using-platelet-rich-fibrin-membrane-application-in-mandibular-anterior-region
#19
Prathahini S Parthiban, R Vijaya Lakshmi, Jaideep Mahendra, K Sreekumar, Ambalavanan Namasivayam
Treatment of edentulous sites with horizontal atrophy represents a clinical situation in which the positioning of endosseous implants might be complex or sometimes impossible without a staged regenerative approach. This case report presents management of horizontally deficient mandibular anterior ridge with a contemporary approach to treatment planning and application of platelet-rich fibrin membrane for ridge split technique and simultaneous implant placement. Implants in anterior mandibular area are considered to be most predictable, stable, with high success rate and patients' satisfaction with implant esthetics...
January 2017: Indian Journal of Dental Research: Official Publication of Indian Society for Dental Research
https://www.readbyqxmd.com/read/28388803/cartilage-scales-embedded-in-fibrin-gel
#20
Milos Kovacevic, Frank Riedel, Jochen Wurm, Gregor M Bran
Multiple techniques have been described for dorsal nasal augmentation in rhinoplasty. In this article, we review common surgical techniques for raising the dorsum or eliminating dorsal irregularities, by highlighting inherent advantages and disadvantages of each method. Within the past few years, the use of diced cartilage grafts has become the workhorse in this field of interest. To overcome drawbacks of methods based on diced cartilage, we present a new concept for autologous augmentation, using regenerative medicine protocols...
April 2017: Facial Plastic Surgery: FPS
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