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JOURNAL ARTICLE
Xuefeng Ma, Min Wang, Weiran Zhou, Zhaojie Zhang, Haosen Ni, Anhang Jiang, Yanbin Zheng, Xiaoxia Du, Marc N Potenza, Guang-Heng Dong
BACKGROUND: Although internet gaming disorder (IGD) has been included in the DSM-5 for approximately 10 years, debate remains regarding its existence and classification. METHODS: The current research incorporated three approaches. First, implicit association tests were used to examine for potential dissociation between wanting and liking in IGD. Second, brain features in wanting and liking circuits were tested and compared with tobacco use disorder (TUD) when performing a cue-craving task to explore the neural features of wanting and liking...
April 17, 2024: Journal of Behavioral Addictions
#22
JOURNAL ARTICLE
Zhefeng Huang, Anthony L Gunderman, Samuel E Wilcox, Saikat Sengupta, Jay Shah, Aiming Lu, David Woodrum, Yue Chen
MR-guided microwave ablation (MWA) has proven effective in treating hepatocellular carcinoma (HCC) with small-sized tumors, but the state-of-the-art technique suffers from sub-optimal workflow due to the limited accuracy provided by the manual needle insertions. This paper presents a compact body-mounted MR-conditional robot that can operate in closed-bore MR scanners for accurate needle guidance. The robotic platform consists of two stacked Cartesian XY stages, each with two degrees of freedom, that facilitate needle insertion pose control...
April 18, 2024: Annals of Biomedical Engineering
#23
JOURNAL ARTICLE
Emmanuel A Tsochatzis, Luca Valenti, Maja Thiele, Sophie Péloquin, Patrice Lazure, Mounia Heddad Masson, Alina M Allen, Jeffrey V Lazarus, Mazen Noureddin, Mary Rinella, Frank Tacke, Suzanne Murray
BACKGROUND AND AIMS: Non-invasive tests (NITs) are underutilized for diagnosis and risk stratification in metabolic dysfunction-associated steatotic liver disease (MASLD), despite good accuracy. This study aimed to identify challenges and barriers to the use of NITs in clinical practice. METHODS: We conducted a qualitative exploratory study in Germany, Italy, United Kingdom and United States. Phase 1 participants (primary care physicians, hepatologists, diabetologists, researchers, healthcare administrators, payers and patient advocates; n = 29) were interviewed...
April 18, 2024: Liver International: Official Journal of the International Association for the Study of the Liver
#24
REVIEW
Abel Tesfai, Natalia Norori, Thomas A Harding, Yui Hang Wong, Matthew David Hobbs
OBJECTIVE: This work aims to examine the latest evidence on the impact of pre-biopsy MRI, in addition to prostate-specific antigen (PSA) testing, on health outcomes and quality of life. METHODS: We conducted a literature search including PubMed and Cochrane Central Register of Controlled Trials (CENTRAL) databases, with a limited scan of (i) guidelines and (ii) references from trial reports, from January 2005 to 25th January 2023. Two independent reviewers selected randomised controlled trials (RCT) and cohort studies which met our inclusion criteria...
April 2024: BJUI compass
#25
JOURNAL ARTICLE
Katherine B McCullough, Amanda Titus, Kate Reardon, Sara Conyers, Joseph D Dougherty, Xia Ge, Joel R Garbow, Patricia Dickson, Carla M Yuede, Susan E Maloney
BACKGROUND: Mucopolysaccharidosis (MPS) IIIB, also known as Sanfilippo Syndrome B, is a devastating childhood disease. Unfortunately, there are currently no available treatments for MPS IIIB patients. Yet, animal models of lysosomal storage diseases have been valuable tools in identifying promising avenues of treatment. Enzyme replacement therapy, gene therapy, and bone marrow transplant have all shown efficacy in the MPS IIIB model systems. A ubiquitous finding across rodent models of lysosomal storage diseases is that the best treatment outcomes resulted from intervention prior to symptom onset...
April 17, 2024: Journal of Neurodevelopmental Disorders
#26
REVIEW
Yuxin Xie, Qiang Zhang
OBJECTIVE: To review the research progress of ultrasound in the diagnosis and treatment of shoulder diseases, in order to provide a theoretical basis for the further development of ultrasound in shoulder surgery. METHODS: The recent literature on the application of ultrasound in the shoulder joint was extensively reviewed. The application of ultrasound in the diagnosis and treatment of shoulder joint diseases, and the advantages and disadvantages of ultrasound were analysed, and the development trend of ultrasound technology in the shoulder joint area was prospected...
April 15, 2024: Chinese Journal of Reparative and Reconstructive Surgery
#27
JOURNAL ARTICLE
Julie K Wisch, Nicole S McKay, Anna H Boerwinkle, James Kennedy, Shaney Flores, Benjamin L Handen, Bradley T Christian, Elizabeth Head, Mark Mapstone, Michael S Rafii, Sid E O'Bryant, Julie C Price, Charles M Laymon, Sharon J Krinsky-McHale, Florence Lai, H Diana Rosas, Sigan L Hartley, Shahid Zaman, Ira T Lott, Dana Tudorascu, Matthew Zammit, Adam M Brickman, Joseph H Lee, Thomas D Bird, Annie Cohen, Patricio Chrem, Alisha Daniels, Jasmeer P Chhatwal, Carlos Cruchaga, Laura Ibanez, Mathias Jucker, Celeste M Karch, Gregory S Day, Jae-Hong Lee, Johannes Levin, Jorge Llibre-Guerra, Yan Li, Francisco Lopera, Jee Hoon Roh, John M Ringman, Charlene Supnet-Bell, Christopher H van Dyck, Chengjie Xiong, Guoqiao Wang, John C Morris, Eric McDade, Randall J Bateman, Tammie L S Benzinger, Brian A Gordon, Beau M Ances
BACKGROUND: In people with genetic forms of Alzheimer's disease, such as in Down syndrome and autosomal-dominant Alzheimer's disease, pathological changes specific to Alzheimer's disease (ie, accumulation of amyloid and tau) occur in the brain at a young age, when comorbidities related to ageing are not present. Studies including these cohorts could, therefore, improve our understanding of the early pathogenesis of Alzheimer's disease and be useful when designing preventive interventions targeted at disease pathology or when planning clinical trials...
May 2024: Lancet Neurology
#28
JOURNAL ARTICLE
Harvi F Hart, Kay M Crossley, Brooke E Patterson, Ali Guermazi, Trevor B Birmingham, Chris Koskoletos, Amélie Michaud, Alysha De Livera, Adam G Culvenor
OBJECTIVE: To determine if global, central, or peripheral adiposity is associated with prevalent and worsening cartilage lesions following anterior cruciate ligament reconstruction (ACLR). METHODS: In 107 individuals one-year post-ACLR, adiposity was assessed globally (body mass index, BMI), centrally (waist circumference), and peripherally (knee subcutaneous adipose tissue thickness) from magnetic resonance imaging (MRI). Tibiofemoral and patellofemoral cartilage lesions were assessed from knee MRIs at 1- and 5-years post-ACLR...
April 15, 2024: Osteoarthritis and Cartilage
#29
JOURNAL ARTICLE
Zach Eidex, Jing Wang, Mojtaba Safari, Eric Elder, Jacob Wynne, Tonghe Wang, Hui-Kuo Shu, Hui Mao, Xiaofeng Yang
BACKGROUND: 7 Tesla (7T) apparent diffusion coefficient (ADC) maps derived from diffusion-weighted imaging (DWI) demonstrate improved image quality and spatial resolution over 3 Tesla (3T) ADC maps. However, 7T magnetic resonance imaging (MRI) currently suffers from limited clinical unavailability, higher cost, and increased susceptibility to artifacts. PURPOSE: To address these issues, we propose a hybrid CNN-transformer model to synthesize high-resolution 7T ADC maps from multimodal 3T MRI...
April 17, 2024: Medical Physics
#30
JOURNAL ARTICLE
Min Dai, Zhongwei Guo, Honglian Xia, Hong Zhu, Jiapeng Li, Hongtao Hou, Guizhi Zhao, Xiaozheng Liu
BACKGROUND: Although donepezil is a commonly used drug for treating Alzheimer's disease (AD), the mechanisms by which it affects patients' functional brain activity, and thus modulates clinical symptoms, remain unclear. METHODS: In the present study, we used resting-state functional magnetic resonance imaging (MRI) and regional homogeneity (ReHo) to investigate the effects of donepezil on local brain activity in AD patients. Resting-state functional MRI data were collected from 32 subjects: 16 healthy controls and 16 AD patients...
April 17, 2024: Aging Clinical and Experimental Research
#31
JOURNAL ARTICLE
Ruimiao Bai, John Ross Bonanni, Jinzhen Guo, Zhankui Li, Xiping Yu, Jinru Zhao, Junan Zeng, Gregory Garvin, Yi Yan
OBJECTIVE: To explore the suitability of conservative management for neonatal ovarian cysts in newborns. METHODS: A retrospective cohort study was conducted, involving infants diagnosed with neonatal abdominal/pelvic cysts at two separate medical institutions from January 2015 through July 2021. Data collection included clinical characteristics, imaging results, pathological findings, and postnatal outcomes. Statistical analyses were performed using the Student's t-test, Mann-Whitney U-test, and receiver operating characteristic (ROC) curve...
April 17, 2024: Journal of Clinical Ultrasound: JCU
#32
JOURNAL ARTICLE
Akshay Bhamidipati, Nishit Mummareddy, Seoiyoung Ahn, Gabriel Bendfeldt, Alexander T Lyons, Surya Gangavarapu, Jeffrey Chen, Jacob Jo, Naveed Kamal, Steven G Roth, Michael T Froehler, Rohan V Chitale, Matthew R Fusco
BACKGROUND: Post-mechanical thrombectomy (MT) intracranial hemorrhage (ICH) is a major source of morbidity in treated acute ischemic stroke patients with large vessel occlusion. ICH expansion may further contribute to morbidity. We sought to identify factors associated with ICH expansion on imaging evaluation post-MT. METHODS: We performed a retrospective cohort study of patients undergoing MT at a single comprehensive stroke center. Per protocol, patients underwent dual-energy head CT (DEHCT) post-MT followed by a 24-h interval non-contrast enhanced MRI...
April 17, 2024: Interventional Neuroradiology
#33
REVIEW
Konstantinos Malandris, Stylianos Papandreou, Despoina Vasilakou, Panagiota Kakotrichi, Anna Sarakapina, Georgios Kalopitas, Thomas Karagiannis, Olga Giouleme, Eleni Bekiari, Aris Liakos, Fotini Iatridi, Paschalis Paschos, Emmanouil Sinakos, Apostolos Tsapas
BACKGROUND AND AIM: Several agents are under investigation for nonalcoholic fatty liver disease (NAFLD). We assessed the comparative efficacy of pharmacologic interventions for patients with NAFLD focusing on magnetic resonance imaging (MRI) biomarkers. METHODS: We searched Medline, Embase, and CENTRAL. We included randomized controlled trials of more than 12 weeks of intervention that recruited patients with biopsy-confirmed or MRI-confirmed NAFLD and assessed the efficacy of interventions on liver fat content (LFC) and fibrosis by means of MRI...
April 16, 2024: Journal of Gastroenterology and Hepatology
#34
JOURNAL ARTICLE
Minseok Choi, Hyun-Chul Kim, Inchan Youn, Song Joo Lee, Jong-Hwan Lee
BACKGROUND: Identification of cortical loci for lower limb movements for stroke rehabilitation is crucial for better rehabilitation outcomes via noninvasive brain stimulation by targeting the fine-grained cortical loci of the movements. However, identification of the cortical loci for lower limb movements using functional MRI (fMRI) is challenging due to head motion and difficulty in isolating different types of movement. Therefore, we developed a custom-made MR-compatible footplate and leg cushion to identify the cortical loci for lower limb movements and conducted multivariate analysis on the fMRI data...
April 16, 2024: Journal of Neuroengineering and Rehabilitation
#35
JOURNAL ARTICLE
T Schlaiss, L Bott, S-L Herbert, C Bartmann, M Kiesel, J Salmen, S T Sauer, S A Christner, B Petritsch, J-P Grunz, A Woeckel, S Löb, J Diessner
PURPOSE: Isolated locoregional recurrence of breast cancer (ILRR) and contralateral breast cancer (CBC) affect up to 20% of all breast cancer (BC) patients in the first 20 years after primary diagnosis. Treatment options comprise surgical interventions and further systemic therapies depending on the histological subtype. Patients with hereditary breast or ovarian cancer (HBOC) undergo MRI, mammography, and ultrasound in the aftercare of BC, while non-HBOC (nHBOC) patients do not regularly receive MRI...
April 17, 2024: Journal of Cancer Research and Clinical Oncology
#36
JOURNAL ARTICLE
Paul J Ryan, Andrew D Duckworth, Jane E McEachan, Paul J Jenkins
AIMS: The underlying natural history of suspected scaphoid fractures (SSFs) is unclear and assumed poor. There is an urgent requirement to develop the literature around SSFs to quantify the actual prevalence of intervention following SSF. Defining the risk of intervention following SSF may influence the need for widespread surveillance and screening of SSF injuries, and could influence medicolegal actions around missed scaphoid fractures. METHODS: Data on SSF were retrospectively gathered from virtual fracture clinics (VFCs) across a large Scottish Health Board over a four-year period, from 1 January 2018 to 31 December 2021...
April 17, 2024: Bone & joint open
#37
JOURNAL ARTICLE
Deborah H Kwon, Shuaiqi Huang, Mustafa Turkmani, Donna Salam, Danah Al-Dieri, Tom Kai Ming Wang, Samir R Kapadia, Amar Krishnaswamy, Marc Gillinov, Lars G Svensson, Richard A Grimm, W H Wilson Tang, David Chen, Christopher T Nguyen, Xiaofeng Wang
BACKGROUND: Significant controversy continues to confound patient selection and referral for revascularization and mitral valve intervention in patients with ischemic cardiomyopathy (ICM). Cardiac magnetic resonance (CMR) enables comprehensive phenotyping with gold-standard tissue characterization and volumetric/functional measures. Therefore, we sought to determine the impact of CMR-enriched phenomapping patients with ICM to identify differential outcomes following surgical revascularization and surgical mitral valve intervention (sMVi)...
April 2024: Circulation. Cardiovascular Imaging
#38
JOURNAL ARTICLE
Hua Yan, Jingzhen He, Anning Li, Dawei Wang, Yuan Yao, Xiaoqin Guo, Xiaoming Zhang, Baodong Jiang
PURPOSE: This study aims to investigate a characteristic cerebellar hemisphere enhancement pattern on magnetic resonance imaging (MRI) that could aid in early and specific diagnosis of intracranial dural arteriovenous fistulas (DAVFs). MATERIALS AND METHODS: Pretreatment MR images of 57 patients with intracranial DAVFs between January 1, 2017, and February 28, 2023, were retrospectively analyzed. A total of 128 patients with confirmed alternative cerebellar lesions during the same period were included as a control group...
April 16, 2024: Journal of Endovascular Therapy
#39
Deepa Singh, Gianluca Scalia, Veeresh U Mathand, Bipin Chaurasia
Meningiomas present diverse clinical and radiological characteristics, with cystic formations constituting a lesser subset but posing significant diagnostic hurdles. We explore the complexities of cystic meningiomas through a distinctive case, highlighting the challenges in diagnosis and management due to their variable presentations. A 54-year-old female from Bengaluru, Karnataka, initially presented with transient memory disturbances. Brain MRI revealed a sizable left frontal cystic lesion exerting a mass effect and midline shift...
April 2024: Clinical Case Reports
#40
Claire Feller, Egambaram Senthilvel
Sleep-disordered breathing (SDB) is a frequently recognized comorbidity in infants and children with achondroplasia due to alterations in craniofacial and upper airway anatomy. Foramen magnum stenosis and cervicomedullary compression can be associated with SDB in this population, requiring prompt evaluation by multidisciplinary teams. Untreated SDB is associated with adverse cardiovascular, metabolic, and behavioral effects in children, necessitating early screening and treatment of underlying causes. Cervicomedullary compression is also associated with increased mortality and sudden infant death in infants with achondroplasia...
March 2024: Curēus
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