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https://www.readbyqxmd.com/read/28637073/-complementary-and-alternative-medicine-in-oncology-what%C3%A2-makes-sense
#1
Axel Eustachi, Dieter Melchart
The basis of any complementary therapy should be the recommendation of a healthy lifestyle (diet, nutrition, exercise, stress-reduction), and appropriate self-help techniques (e. g. thermotherapy, herbal OTC-products) aimed at releasing the patients' most debilitating symptoms. For therapy-resistant or strong symptoms, more invasive interventions or medical treatments with an acceptable evidence base can be used (e. g. acupuncture for cancer pain, herbal prescriptions). The effects of any complementary intervention should be controlled for a period of six weeks after its administration...
June 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28637072/-how-to-classify-and-evaluate-complementary-and-alternative-medicines-in-oncology
#2
Anke Ernst, Stefanie Klein
There are a vast number of complementary and alternative medicines (CAM) in oncology. Also patients' needs for information on these methods are growing. Helping patients to classify and evaluate CAM methods is a challenge. The Cancer Information Service at the German Cancer Research Center has developed a benefit-risk-assessment based on evidence-based medicine and individual patient traits: To rate a CAM's benefit, the scientific evidence and the patient's therapeutic goals have to be taken into account. To estimate its risks, both, the method itself and the patient's status of health must be considered...
June 2017: Deutsche Medizinische Wochenschrift
https://www.readbyqxmd.com/read/28629411/prevalence-and-predictors-of-complementary-and-alternative-medicine-use-among-people-with-coronary-heart-disease-or-at-risk-for-this-in-the-sixth-troms%C3%A3-study-a-comparative-analysis-using-protection-motivation-theory
#3
Agnete E Kristoffersen, Fuschia M Sirois, Trine Stub, Anne Helen Hansen
BACKGROUND: Engagement in healthy lifestyle behaviors, such as healthy diet and regular physical activity, are known to reduce the risk of developing coronary heart disease (CHD). Complementary and alternative medicine (CAM) is known to be associated with having a healthy lifestyle. The primary aim of this study was to examine the prevalence and predictors of CAM use in CHD patients, and in those without CHD but at risk for developing CHD, using Protection Motivation Theory (PMT) as a guiding conceptual framework...
June 19, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28629290/functional-foods-how-functional-are-they-a-case-report-of-supplement-induced-psychosis
#4
Priyanka Yadav, Kyle Stigall, Hannah E Johnson, Abner O Rayapati, Nitin Chopra
There is rising evidence of patients' use of alternative and complementary medicine. The percentage of the U.S. population who used at least one dietary supplement increased from 42% in 1988-1994 to 53% in 2003-2006. We present a case of an Asian female in her 40s, with no previous psychiatric illness, who presented to the emergency room following a brief psychotic episode, during which she self-amputated the tips of her fingers, after using multivitamins and herbal supplements including ginseng, gui yuan rou (Chinese herb), astaxanthin, goji (Chinese fruit), selenium, saw palmetto, grape seed extract, citrus bioflavanoid, lutein (zeaxantin), resvexatrol, sun chlorella, spirulina powder, phytoceramides, phytoestrogen, glucosatrin, bromelain plus, and American bee pollen...
August 2016: International Journal of Psychiatry in Medicine
https://www.readbyqxmd.com/read/28627237/characteristic-analysis-of-complementary-and-alternative-medicine-in-randomized-controlled-trials-of-oncology
#5
Huiqing Zhang, Geliang Yang, Wei Zhang, Wei Gu, Yonghua Su, Changquan Ling
BACKGROUND: Complementary and alternative medicine (CAM) has been widely used by cancer patients and oncologists in the past decades. The present study aimed to examine and compare the characteristics and registration status of published studies in a sample of recently published CAM randomized controlled trial (RCT) reports of oncology in leading journals of 3 categories: general and internal medicine (GIM), clinical oncology (CO), and CAM. METHODS: Articles published in the top 5 journals of the 3 categories from 2006 to 2015 were searched in PubMed...
March 1, 2017: Integrative Cancer Therapies
https://www.readbyqxmd.com/read/28625475/prediction-of-protein-protein-interactions-by-label-propagation-with-protein-evolutionary-and-chemical-information-derived-from-heterogeneous-network
#6
Yu-Ting Wen, Hai-Jun Lei, Zhu-Hong You, Bai-Ying Lei, Xing Chen, Li-Ping Li
Prediction of protein-protein interactions (PPIs) is of great significance. To achieve this, we propose a novel computational method for PPIs prediction based on a similarity network fusion (SNF) model for integrating the physical and chemical properties of proteins. Specifically, the physical and chemical properties of protein are the protein amino acid mutation rate and its hydrophobicity, respectively. The amino acid mutation rate is extracted using a BLOSUM62 matrix, which puts the protein sequence into block substitution matrix...
June 15, 2017: Journal of Theoretical Biology
https://www.readbyqxmd.com/read/28625036/sago-worms-as-a-nutritious-traditional-and-alternative-food-for-rural-children-in-southeast-sulawesi-indonesia
#7
Intan R Nirmala, Trees, Suwarni, Mochammad S Pramono
BACKGROUND AND OBJECTIVES: The sago worm Rhynchophorus ferrugineus is a nutritious food source found in the remaining parts of a sago palm trunk after the removal of sago starch by farmers. The effort to increase sago worm consumption is investigated in an intervention study among children aged <5 years. METHODS AND STUDY DESIGN: Children aged 1-5 years were allocated to a sago worm inclusive diet (n=10) and to a control group eating a usual diet, but without sago worms (n=13)...
June 2017: Asia Pacific Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28624389/plasma-proteome-analysis-in-patients-with-pulmonary-arterial-hypertension-an-observational-cohort-study
#8
Christopher J Rhodes, John Wharton, Pavandeep Ghataorhe, Geoffrey Watson, Barbara Girerd, Luke S Howard, J Simon R Gibbs, Robin Condliffe, Charles A Elliot, David G Kiely, Gerald Simonneau, David Montani, Olivier Sitbon, Henning Gall, Ralph T Schermuly, H Ardeschir Ghofrani, Allan Lawrie, Marc Humbert, Martin R Wilkins
BACKGROUND: Idiopathic and heritable pulmonary arterial hypertension form a rare but molecularly heterogeneous disease group. We aimed to measure and validate differences in plasma concentrations of proteins that are associated with survival in patients with idiopathic or heritable pulmonary arterial hypertension to improve risk stratification. METHODS: In this observational cohort study, we enrolled patients with idiopathic or heritable pulmonary arterial hypertension from London (UK; cohorts 1 and 2), Giessen (Germany; cohort 3), and Paris (France; cohort 4)...
June 14, 2017: Lancet Respiratory Medicine
https://www.readbyqxmd.com/read/28623884/mitochondrial-rna-processing-in-absence-of-trna-punctuations-in-octocorals
#9
Gaurav G Shimpi, Sergio Vargas, Angelo Poliseno, Gert Wörheide
BACKGROUND: Mitogenome diversity is staggering among early branching animals with respect to size, gene density, content and order, and number of tRNA genes, especially in cnidarians. This last point is of special interest as tRNA cleavage drives the maturation of mitochondrial mRNAs and is a primary mechanism for mt-RNA processing in animals. Mitochondrial RNA processing in non-bilaterian metazoans, some of which possess a single tRNA gene in their mitogenomes, is essentially unstudied despite its importance in understanding the evolution of mitochondrial transcription in animals...
June 17, 2017: BMC Molecular Biology
https://www.readbyqxmd.com/read/28623589/aranet-a-network-biology-server-for-arabidopsis-thaliana-and-other-non-model-plant-species
#10
Tak Lee, Insuk Lee
Functional gene networks link genes based on their functional relatedness, which is inferred from various complementary biological datasets. Gene networks comprising vast amounts of data can be used to predict which genes are associated with complex traits. Decades of studies in plant biology using the model organism Arabidopsis thaliana have generated large amounts of information, enabling the development of a system-level molecular network. AraNet (currently version 2) is a genome-scale functional gene network for Arabidopsis thaliana, constructed by integrating 19 types of genomics data and can be explored through a web-server (http://www...
2017: Methods in Molecular Biology
https://www.readbyqxmd.com/read/28621350/photoinduced-structural-distortions-and-singlet-triplet-intersystem-crossing-in-cu-i-mlct-excited-states-monitored-by-optically-gated-fluorescence-spectroscopy
#11
Sofia Garakyaraghi, Petr Koutnik, Felix N Castellano
Copper(i) phenanthroline complexes represent viable earth-abundant alternatives to the ubiquitous Ru(ii) tris-bipyridine photosensitizers owing to their similar metal-to-ligand charge transfer (MLCT) properties. A well-established complication of Cu(i) phenanthroline complexes is that they can undergo significant photo-induced structural rearrangements, leading to excited states that are highly susceptible to exciplex formation and short-lived. In this work, a comprehensive analysis of the photo-induced structural distortions and singlet-triplet intersystem crossing dynamics of a series of four sterically encumbered Cu(i) phenanthroline chromophores has been conducted, namely, [Cu(dsbp)2](+) (dsbp = 2,9-di-sec-butyl-1,10-phenanthroline), [Cu(dsbtmp)2](+) (dsbtmp = 2,9-di-sec-butyl-3,4,7,8-tetramethyl-1,10-phenanthroline), [Cu(dipp)2](+) (dipp = 2,9-di-isopropyl-1,10-phenanthroline), and [Cu(diptmp)2](+) (diptmp = 2,9-di-isopropyl-3,4,7,8-tetramethyl-1,10-phenanthroline)...
June 16, 2017: Physical Chemistry Chemical Physics: PCCP
https://www.readbyqxmd.com/read/28621295/efficacy-and-safety-in-case-of-technical-success-of-endoscopic-ultrasound-guided-transhepatic-antegrade-biliary-drainage-a-report-of-a-monocentric-study
#12
Sébastien Godat, Erwan Bories, Fabrice Caillol, Christian Pesenti, Jean Philippe Ratone, Chiara de Cassan, Marc Giovannini
BACKGROUND AND OBJECTIVES: Endoscopic ultrasound (EUS)-guided biliary drainage techniques are alternative procedures in cases of obstructive jaundice with altered anatomy or failed ERCP. Complications related to EUS-guided antegrade drainage (EUS-AD) are still present in up to 10% of cases, and combination of procedures is sometimes suggested to avoid adverse events. The purpose of our study is to evaluate the efficacy and safety of EUS-AD with transhepatic access in case of technical success...
May 2017: Endoscopic Ultrasound
https://www.readbyqxmd.com/read/28619298/alternative-medicine-worker-health-and-absenteeism-in-the-united-states
#13
Kate Rybczynski
Health related absenteeism costs an estimated $153 billion annually in the United States (Witters and Agrawal, 2011).(1) Chronic conditions (major contributors to absenteeism) are often successfully managed by Complementary and Alternative Medicine (CAM). As CAM becomes an increasingly visible component of healthcare, firms may wish to consider whether CAM therapies can help reduce illness-related absenteeism. This paper aims to extend the literature on healthcare utilization and absenteeism by exploring whether CAM treatment is associated with fewer workdays missed due to illness...
June 2017: Complementary Therapies in Medicine
https://www.readbyqxmd.com/read/28619197/traditional-chinese-medicine-for-cardiovascular-disease-evidence-and-potential-mechanisms
#14
REVIEW
Panpan Hao, Fan Jiang, Jing Cheng, Lianyue Ma, Yun Zhang, Yuxia Zhao
Traditional Chinese medicine (TCM) has more than 2,000 years of history and has gained widespread clinical applications. However, the explicit role of TCM in preventing and treating cardiovascular disease remains unclear due to a lack of sound scientific evidence. Currently available randomized controlled trials on TCM are flawed, with small sample sizes and diverse outcomes, making it difficult to draw definite conclusions about the actual benefits and harms of TCM. Here, we systematically assessed the efficacy and safety of TCM for cardiovascular disease, as well as the pharmacological effects of active TCM ingredients on the cardiovascular system and potential mechanisms...
June 20, 2017: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/28619075/anti-inflammatory-effect-of-chang-an-shuan-on-tnbs-induced-experimental-colitis-in-rats
#15
Hong Mi, Feng-Bin Liu, Hai-Wen Li, Jiang-Tao Hou, Pei-Wu Li
BACKGROUND: Inflammatory bowel disease (IBD), denominated by Crohn's disease and ulcerative colitis, is often associated with abdominal pain, diarrhea and bloody stool. The standard protocols for treating colitis conditions are not satisfactory; thus, complementary and alternative medicines have been increasingly accepted by IBD sufferers worldwide. In this study, we aimed to elucidate the anti-inflammatory effect of Chang-An-Shuan (CAS), a 6-herb Chinese medicinal formula, on 2, 4, 6-trinitrobenzenesulfonic acid (TNBS)-induced colitis in rats and the underlying mechanisms...
June 15, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28616349/sparing-aortic-valve-techniques
#16
Rubén Álvarez-Cabo
Prosthetic valve implantation is the most widely used therapeutic option for aortic regurgitation (AR), but complications associated with prosthetic valves, with an incidence of 3-5% patient/year, and the need for anticoagulation in mechanical valves, force us to consider aortic valve repair as an alternative to the prosthetic implant, especially in young people with many potential years of life for these complications. Aortic valve repair techniques are not excessively complicated, but there is no standardization, so they are not reproducible in all medical centers...
May 2017: Journal of Thoracic Disease
https://www.readbyqxmd.com/read/28615153/-click-for-closer-care-a-content-analysis-of-community-pharmacy-websites-in-four-countries
#17
Sandra Zwier
BACKGROUND: Combinations of professional and commercial communication are typically very controversial, particularly in health care communication on the Internet. Websites of licensed community pharmacies on the other hand tend to raise remarkably little controversy, although they typically contain controversial combinations of clinical and commercial services previously unprecedented in professional health care communication. OBJECTIVE: The aim of this study was to fill the void of knowledge about the combination of clinical and commercial services presented on the websites of licensed community pharmacies...
June 14, 2017: Journal of Medical Internet Research
https://www.readbyqxmd.com/read/28615021/general-perception-and-self-practice-of-complementary-and-alternative-medicine-cam-among-undergraduate-pharmacy-students-of-bangladesh
#18
Bijoy Laxmi Saha, Md Omar Reza Seam, Md Mainul Islam, Abhijit Das, Sayed Koushik Ahamed, Palash Karmakar, Md Fokhrul Islam, Sukalyan Kumar Kundu
BACKGROUND: Complementary and Alternative Medicine (CAM) is a combination of herbal medicine, traditional therapies, and mind-body intervention. This descriptive study was designed to assess the knowledge, attitudes, perception and self-use of CAM among Bangladeshi undergraduate pharmacy students. The study also evaluated their opinions about its integration into the pharmacy course curriculum. METHODS: It was a cross-sectional, questionnaire-based study conducted on 250 pharmacy students of five reputed public universities of Bangladesh...
June 14, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/28613834/amino-functionalized-5-cap-analogs-as-tools-for-site-specific-sequence-independent-labeling-of-messenger-rna
#19
Marcin Warminski, Pawel J Sikorski, Zofia Warminska, Maciej Lukaszewicz, Anna Kropiwnicka, Joanna Zuberek, Edward Darzynkiewicz, Joanna Kowalska, Jacek Jemielity
mRNA is a template for protein biosynthesis, and consequently mRNA transport, translation, and turnover are key elements in the overall regulation of gene expression. Along with growing interest in the mechanisms regulating mRNA decay and localization, there is an increasing need for tools enabling convenient fluorescent labelling or affinity tagging of mRNA. We report new mRNA 5' cap analog-based tools that enable site-specific labelling of RNA within the cap using N-hydroxysuccinimide (NHS) chemistry. We explored two complementary methods: a co-transcriptional labelling method, in which the label is first attached to cap analog and then incorporated into RNA by transcription in vitro, and post-transcriptional labelling method, in which an amino-functionalized cap analog is incorporated into RNA followed by chemical labelling of the resulting transcript...
June 14, 2017: Bioconjugate Chemistry
https://www.readbyqxmd.com/read/28612665/granular-cell-tumor-of-the-neurohypophysis-with-tfe-3-expression-a-rare-case-report
#20
Guang-Zhi Yang, Jing Li
Granular cell tumor (GCT) rarely involves the central nervous system, and fewer than 100 cases have been reported in English literatures. We herein report a case of a 36-year-old Chinese man with GCT of the neurohypophysis. Magnetic resonance imaging showed one mass located in the hypophysis with heterogeneous contrast enhancement. Pathological examination showed a neoplasm comprising densely packed polygonal cells of ample cytoplasm with abundant eosinophilic granules inside. The nuclei were small with inconspicuous nucleoli and yet without any mitoses...
June 1, 2017: International Journal of Surgical Pathology
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