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https://www.readbyqxmd.com/read/29676534/consensus-based-european-guidelines-for-treatment-of-atopic-eczema-atopic-dermatitis-in-adults-and-children-part-i
#1
A Wollenberg, S Barbarot, T Bieber, S Christen-Zaech, M Deleuran, A Fink-Wagner, U Gieler, G Girolomoni, S Lau, A Muraro, M Czarnecka-Operacz, T Schäfer, P Schmid-Grendelmeier, D Simon, Z Szalai, J C Szepietowski, A Taïeb, A Torrelo, T Werfel, J Ring
This guideline was developed as a joint interdisciplinary European project, including physicians from all relevant disciplines as well as patients. It is a consensus-based guideline, taking available evidence from other guidelines, systematic reviews and published studies into account. This first part of the guideline covers methods, patient perspective, general measures and avoidance strategies, basic emollient treatment and bathing, dietary intervention, topical anti-inflammatory therapy, phototherapy and antipruritic therapy, whereas the second part covers antimicrobial therapy, systemic treatment, allergen-specific immunotherapy, complementary medicine, psychosomatic counselling and educational interventions...
May 2018: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/29676072/current-management-of-moderate-to-severe-atopic-dermatitis-a-survey-of-allergists-pediatric-allergists-and-dermatologists-in-korea
#2
Hye Yung Yum, Hyun Hee Kim, Hyun Jung Kim, Woo Kyung Kim, So Yeon Lee, Kapsok Li, Dong Hun Lee
PURPOSE: There is an unmet need for the treatment of moderate-to-severe atopic dermatitis (AD), leading to variation in management strategies. To investigate distinct features and treatment modalities according to physicians' specialties, we collected data on the current treatment approach to moderate-to-severe AD among allergists, pediatric allergists and dermatologists in Korea. METHODS: This questionnaire-based study was administered to physicians from the Korean Academy of Asthma, Allergy and Clinical Immunology (KAAACI), Korean Academy of Pediatric Allergy and Respiratory Disease (KAPARD), and Korean Atopic Dermatitis Association (KADA)...
May 2018: Allergy, Asthma & Immunology Research
https://www.readbyqxmd.com/read/29675642/dutch-guideline-for-clinical-foetal-neonatal-and-paediatric-post-mortem-radiology-including-a-review-of-literature
#3
REVIEW
L J P Sonnemans, M E M Vester, E E M Kolsteren, J J H M Erwich, P G J Nikkels, P A M Kint, R R van Rijn, W M Klein
Clinical post-mortem radiology is a relatively new field of expertise and not common practice in most hospitals yet. With the declining numbers of autopsies and increasing demand for quality control of clinical care, post-mortem radiology can offer a solution, or at least be complementary. A working group consisting of radiologists, pathologists and other clinical medical specialists reviewed and evaluated the literature on the diagnostic value of post-mortem conventional radiography (CR), ultrasonography, computed tomography (PMCT), magnetic resonance imaging (PMMRI), and minimally invasive autopsy (MIA)...
April 19, 2018: European Journal of Pediatrics
https://www.readbyqxmd.com/read/29671263/high-throughput-screening-method-to-identify-alternative-splicing-regulators
#4
Cheryl Stork, Sika Zheng
Misregulation of alternative pre-mRNA splicing contributes to various diseases. Understanding how alternative splicing is regulated paves the way to modulating or correcting molecular pathogenesis of the diseases. Alternative splicing is typically regulated by trans RNA binding proteins and their upstream modulators. Identification of these splicing regulators has been difficult and traditionally done piecemeal. High-throughput screening strategies to find multiple regulators of exon splicing have great potential to accelerate the discovery process, but typically confront low sensitivity and specificity of splicing assays...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29668418/-68-ga-prostate-specific-membrane-antigen-pet-ct-for-primary-diagnosis-of-prostate-cancer-complementary-or-alternative-to-multiparametric-mr-imaging
#5
Egesta Lopci, Giorgio Guazzoni, Massimo Lazzeri
No abstract text is available yet for this article.
May 2018: Radiology
https://www.readbyqxmd.com/read/29668401/phase-ii-randomized-controlled-trial-of-constraint-induced-movement-therapy-in-multiple-sclerosis-part-2-effect-on-white-matter-integrity
#6
Ameen Barghi, Jane B Allendorfer, Edward Taub, Brent Womble, Jarrod M Hicks, Gitendra Uswatte, Jerzy P Szaflarski, Victor W Mark
BACKGROUND: Constraint-induced movement therapy (CIMT) is a method of physical rehabilitation that has demonstrated clinical efficacy in patients with chronic stroke, cerebral palsy, and multiple sclerosis (MS). OBJECTIVE: This pilot randomized controlled trial tested whether CIMT can also induce increases in white matter integrity in patients with MS. METHODS: Twenty adults with chronic hemiparetic MS were randomized to receive either CIMT or complementary and alternative medicine (CAM) treatment (reported in the first article of this pair)...
March 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29668399/phase-ii-randomized-controlled-trial-of-constraint-induced-movement-therapy-in-multiple-sclerosis-part-1-effects-on-real-world-function
#7
Victor W Mark, Edward Taub, Gitendra Uswatte, David M Morris, Gary R Cutter, Terrie L Adams, Mary H Bowman, Staci McKay
BACKGROUND: Constraint-Induced Movement therapy (CIMT) has controlled evidence of efficacy for improving real-world paretic limb use in non-progressive physically disabling disorders (stroke, cerebral palsy). OBJECTIVE: This study sought to determine whether this therapy can produce comparable results with a progressive disorder such as multiple sclerosis (MS). We conducted a preliminary phase II randomized controlled trial of CIMT versus a program of complementary and alternative medicine (CAM) treatments for persons with MS, to evaluate their effect on real-world disability...
March 2018: Neurorehabilitation and Neural Repair
https://www.readbyqxmd.com/read/29662720/role-of-active-versus-passive-complementary-and-integrative-health-approaches-in-pain-management
#8
David Cosio, Erica Lin
Background: A general conclusion about the treatment of chronic, noncancer pain is that the results from traditional, passive modalities are disheartening. Perhaps this may be due to the propensity of patients to seek out passive versus active treatments. In pain management, active treatments should be the primary focus, with passive interventions as an adjunct. Objective: The current study tested the hypotheses that Veterans would report a greater significant increase in active versus transitional and active versus passive complementary and integrative health (CIH) utilization after completing a formal pain education program...
2018: Global Advances in Health and Medicine: Improving Healthcare Outcomes Worldwide
https://www.readbyqxmd.com/read/29662302/hot-water-extract-of-the-branches-of-hovenia-dulcis-thunb-rhamnaceae-ameliorates-low-fiber-diet-induced-constipation-in-rats
#9
Chul-Yung Choi, Seung-Sik Cho, In-Soo Yoon
Hovenia dulcis Thunb. (Rhamnaceae), also known as oriental raisin tree, is used in traditional herbal medicine. Its extracts have been reported to show various pharmacological effects such as hepatoprotection, antitumor, antiatopic dermatitis, antilipid peroxidation, anti-steatotic, anti-inflammatory, and antiallergic activities. However, there have been no reports on the effect of H. dulcis extracts in relieving constipation so far. The aim of this study was to investigate the effects of a hot-water extract of the branches of H...
2018: Drug Design, Development and Therapy
https://www.readbyqxmd.com/read/29660322/efficacy-and-safety-of-endobiliary-radiofrequency-ablation-for-the-eradication-of-residual-neoplasia-after-endoscopic-papillectomy-a-multicenter-prospective-study
#10
Marine Camus, Bertrand Napoléon, Ariane Vienne, Marc Le Rhun, Sarah Leblanc, Maximilien Barret, Stanislas Chaussade, Françoise Robin, Nadira Kaddour, Frederic Prat
BACKGROUND: and study aims: Endobiliary dysplasia may persist after endoscopic papillectomy. Intraductal radiofrequency ablation (ID-RFA) is a potential alternative to complementary surgery. The aim of the study was to evaluate the efficacy and safety of ID-RFA for the treatment of adenomatous intraductal residue after endoscopic papillectomy. PATIENTS AND METHODS: A prospective open-label multicenter study included patients with histologically proven endobiliary adenoma remnant (ductal extent <20 mm), after endoscopic papillectomy for ampullary tumor...
April 13, 2018: Gastrointestinal Endoscopy
https://www.readbyqxmd.com/read/29660193/screening-of-semifluorinated-n-alkanes-by-gas-chromatography-coupled-to-dielectric-barrier-discharge-ionization-mass-spectrometry-gc-dbdi-ms
#11
Sebastian Hagenhoff, Ansgar Korf, Ullrich Markgraf, Sebastian Brandt, Alexander Schütz, Joachim Franzke, Heiko Hayen
RATIONALE: The potential of an atmospheric pressure ionization source based on a dielectric barrier discharge in helium for the hyphenation of gas chromatography and mass spectrometry (GC/DBDI-MS) has been demonstrated only recently and for a limited range of compounds. Due to its 'soft' ionization properties and the possibility to choose from a variety of atmospheric pressure ionization MS instruments, GC/DBDI-MS has the potential to be an interesting alternative to 'classic' GC/MS techniques...
April 16, 2018: Rapid Communications in Mass Spectrometry: RCM
https://www.readbyqxmd.com/read/29659610/dna-metabarcoding-and-microscopic-analyses-of-sea-turtles-biofilms-complementary-to-understand-turtle-behavior
#12
Sinziana F Rivera, Valentin Vasselon, Katia Ballorain, Alice Carpentier, Carlos E Wetzel, Luc Ector, Agnès Bouchez, Frédéric Rimet
Sea turtles are distributed in tropical and subtropical seas worldwide. They play several ecological roles and are considered important indicators of the health of marine ecosystems. Studying epibiotic diatoms living on turtle shells suggestively has great potential in the study of turtle behavior because diatoms are always there. However, diatom identification at the species level is time consuming, requires well-trained specialists, and there is a high probability of finding new taxa growing on turtle shells, which makes identification tricky...
2018: PloS One
https://www.readbyqxmd.com/read/29655353/vapor-phase-nucleation-of-the-short-chain-n-alkanes-n-pentane-n-hexane-and-n-heptane-experiments-and-monte-carlo-simulations
#13
Kehinde E Ogunronbi, Aliasghar Sepehri, Bin Chen, Barbara E Wyslouzil
We measured the nucleation rates of n-pentane through n-heptane in a supersonic nozzle at temperatures ranging from ca. 109 K to 168 K. For n-pentane and n-hexane, these are the first nucleation rate measurements that have been made, and the trends in the current data agree well with those in the earlier work of Ghosh et al. [J. Chem. Phys. 132, 024307 (2010)] for longer chain alkanes. Complementary Monte Carlo simulations, using the transferable potentials for phase equilibria-united atom potentials, suggest that despite the high degree of supercooling, the critical clusters remain liquid like under experimental conditions for n-pentane through n-heptane, but adopt more ordered structures for n-octane and n-nonane...
April 14, 2018: Journal of Chemical Physics
https://www.readbyqxmd.com/read/29652885/phosphorelay-through-the-bifunctional-phosphotransferase-phyt-controls-the-general-stress-response-in-an-alphaproteobacterium
#14
Lisa Gottschlich, Miriam Bortfeld-Miller, Christoph Gäbelein, Sebastian Dintner, Julia A Vorholt
Two-component systems constitute phosphotransfer signaling pathways and enable adaptation to environmental changes, an essential feature for bacterial survival. The general stress response (GSR) in the plant-protecting alphaproteobacterium Sphingomonas melonis Fr1 involves a two-component system consisting of multiple stress-sensing histidine kinases (Paks) and the response regulator PhyR; PhyR in turn regulates the alternative sigma factor EcfG, which controls expression of the GSR regulon. While Paks had been shown to phosphorylate PhyR in vitro, it remained unclear if and under which conditions direct phosphorylation happens in the cell, as Paks also phosphorylate the single domain response regulator SdrG, an essential yet enigmatic component of the GSR signaling pathway...
April 2018: PLoS Genetics
https://www.readbyqxmd.com/read/29651870/utilization-of-complementary-and-alternative-medicine-in-multiethnic-population-the-malaysian-cohort-study
#15
Noraidatulakma Abdullah, Boekhtiar Borhanuddin, Afzan Effiza Abdul Patah, Mohd Shaharom Abdullah, Andri Dauni, Mohd Arman Kamaruddin, Shamsul Azhar Shah, Rahman Jamal
BACKGROUND: This study aimed to identify the factors of CAM usage for general health and to determine the factors associated with the usage of different types of CAM after the diagnosis of chronic diseases among The Malaysian Cohort participants. METHODS: This was a cross-sectional study derived from The Malaysian Cohort (TMC) project, a prospective population-based cohort aged between 35 to 65 years old that recruited from April 2006 to September 2012. Association between the CAM usage and contributing factors were determined via logistic regression...
January 2018: Journal of evidence-based integrative medicine
https://www.readbyqxmd.com/read/29650089/complementary-and-alternative-medicine-for-diabetes
#16
Loren D Grossman, Robert Roscoe, Anita R Shack
No abstract text is available yet for this article.
April 2018: Canadian Journal of Diabetes
https://www.readbyqxmd.com/read/29642865/serum-leucine-rich-alpha-2-glycoprotein-1-with-fucosylated-triantennary-n-glycan-a-novel-colorectal-cancer-marker
#17
Eiji Shinozaki, Kazuhiro Tanabe, Takashi Akiyoshi, Tomohiro Tsuchida, Yuko Miyazaki, Nozomi Kojima, Masahiro Igarashi, Masashi Ueno, Mitsukuni Suenaga, Nobuyuki Mizunuma, Kensei Yamaguchi, Konosuke Nakayama, Sadayo Iijima, Toshiharu Yamaguchi
BACKGROUND: Carcinoembryonic antigen (CEA) and carbohydrate antigen (CA)19-9 are used in clinical practice as tumor markers to diagnose or monitor colorectal cancer (CRC) patients, However, their specificities and sensitivities are not ideal, and novel alternatives are needed. In this study, mass spectrometry was used to search for screening markers, focusing on glycan alterations of glycoproteins in the sera of CRC patients. METHODS: Glycopeptides were prepared from serum glycoproteins separated from blood samples of 80 CRC patients and 50 healthy volunteers, and their levels were measured by liquid chromatography time-of flight mass spectrometry (LC-TOF-MS)...
April 11, 2018: BMC Cancer
https://www.readbyqxmd.com/read/29628963/the-effect-of-acupressure-on-physiological-parameters-of-myocardial-infarction-patients-a-randomized-clinical-trial
#18
Marzieh Batvani, Hojatollah Yousefi, Mahboubeh Valiani, Javad Shahabi, Hossein Mardanparvar
Background: Myocardial infarction is a major complication of coronary heart disease, and due to high mortality, is a part of important medical emergencies. Today, complementary and alternative medicine, as nonpharmacological and health promotion methods is considered. Therefore, this study was designed to evaluate the effectiveness of acupressure on physiological parameters of patients with myocardial infarction. Materials and Methods: This clinical trial was carried out among two groups and three stages in 2015...
March 2018: Iranian Journal of Nursing and Midwifery Research
https://www.readbyqxmd.com/read/29627045/advanced-technologies-for-imaging-and-visualization-of-the-tracheobronchial-tree-from-computed-tomography-and-mri-to-virtual-endoscopy
#19
REVIEW
Micheal C McInnis, Gordon Weisbrod, Heidi Schmidt
Advanced imaging plays an increasingly important role in the evaluation of the trachea. The use of computed tomography (CT) has evolved to include multi-planar reconstructions and 3-dimensional reconstructions for the evaluation of benign and malignant disease of the trachea. Advanced applications of CT include dynamic expiratory imaging for the diagnosis of tracheomalacia and virtual endoscopy as a complementary or alternative examination to flexible bronchoscopy. MRI of the trachea has limited applications but may see increased use in the future...
May 2018: Thoracic Surgery Clinics
https://www.readbyqxmd.com/read/29626406/competing-logics-and-healthcare-comment-on-re-making-the-procrustean-bed-standardization-and-customization-as-competing-logics-in-healthcare
#20
Mike Saks
This paper offers a short commentary on the editorial by Mannion and Exworthy. The paper highlights the positive insights offered by their analysis into the tensions between the competing institutional logics of standardization and customization in healthcare, in part manifested in the conflict between managers and professionals, and endorses the plea of the authors for further research in this field. However, the editorial is criticized for its lack of a strong societal reference point, the comparative absence of focus on hybridization, and its failure to highlight structural factors impinging on the opposing logics in a broader neo-institutional framework...
August 20, 2017: International Journal of Health Policy and Management
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