keyword
MENU ▼
Read by QxMD icon Read
search

pandemic planning

keyword
https://www.readbyqxmd.com/read/27932782/cdc-grand-rounds-modeling-and-public-health-decision-making
#1
Leah S Fischer, Scott Santibanez, Richard J Hatchett, Daniel B Jernigan, Lauren Ancel Meyers, Phoebe G Thorpe, Martin I Meltzer
Mathematical models incorporate various data sources and advanced computational techniques to portray real-world disease transmission and translate the basic science of infectious diseases into decision-support tools for public health. Unlike standard epidemiologic methods that rely on complete data, modeling is needed when there are gaps in data. By combining diverse data sources, models can fill gaps when critical decisions must be made using incomplete or limited information. They can be used to assess the effect and feasibility of different scenarios and provide insight into the emergence, spread, and control of disease...
December 9, 2016: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/27929449/reviewing-the-history-of-pandemic-influenza-understanding-patterns-of-emergence-and-transmission
#2
REVIEW
Patrick R Saunders-Hastings, Daniel Krewski
For centuries, novel strains of influenza have emerged to produce human pandemics, causing widespread illness, death, and disruption. There have been four influenza pandemics in the past hundred years. During this time, globalization processes, alongside advances in medicine and epidemiology, have altered the way these pandemics are experienced. Drawing on international case studies, this paper provides a review of the impact of past influenza pandemics, while examining the evolution of our understanding of, and response to, these viruses...
December 6, 2016: Pathogens
https://www.readbyqxmd.com/read/27919245/one-day-workshop-based-training-improves-physical-activity-prescription-knowledge-in-latin-american-physicians-a-pre-test-post-test-study
#3
Maria C Arciniegas Calle, Felipe Lobelo, Mario A Jiménez, Diana C Páez, Sebastian Cortés, Andrés de Lima, John Duperly
BACKGROUND: The physical inactivity pandemic and related non-communicable diseases have made it imperative for medical doctors (MDs) to effectively provide lifestyle counseling as part of prevention and treatment plans for patients. A one-day certification workshop was designed to improve MDs PA prescription knowledge, as part of the Exercise is Medicine® (EIM®) global health initiative. The objective was to determine knowledge gain of MDs participating in a standardized, one-day PA prescription workshop performed throughout Latin America (LA)...
December 5, 2016: BMC Public Health
https://www.readbyqxmd.com/read/27918958/drivers-of-airborne-human-to-human-pathogen-transmission
#4
REVIEW
Sander Herfst, Michael Böhringer, Basel Karo, Philip Lawrence, Nicola S Lewis, Michael J Mina, Charles J Russell, John Steel, Rik L de Swart, Christian Menge
Airborne pathogens - either transmitted via aerosol or droplets - include a wide variety of highly infectious and dangerous microbes such as variola virus, measles virus, influenza A viruses, Mycobacterium tuberculosis, Streptococcus pneumoniae, and Bordetella pertussis. Emerging zoonotic pathogens, for example, MERS coronavirus, avian influenza viruses, Coxiella, and Francisella, would have pandemic potential were they to acquire efficient human-to-human transmissibility. Here, we synthesize insights from microbiological, medical, social, and economic sciences to provide known mechanisms of aerosolized transmissibility and identify knowledge gaps that limit emergency preparedness plans...
December 2, 2016: Current Opinion in Virology
https://www.readbyqxmd.com/read/27916341/hospital-influenza-pandemic-stockpiling-needs-a-computer-simulation
#5
Mark N Abramovich, John C Hershey, Byron Callies, Amesh A Adalja, Pritish K Tosh, Eric S Toner
BACKGROUND: A severe influenza pandemic could overwhelm hospitals but planning guidance that accounts for the dynamic interrelationships between planning elements is lacking. We developed a methodology to calculate pandemic supply needs based on operational considerations in hospitals and then tested the methodology at Mayo Clinic in Rochester, MN. METHODS: We upgraded a previously designed computer modeling tool and input carefully researched resource data from the hospital to run 10,000 Monte Carlo simulations using various combinations of variables to determine resource needs across a spectrum of scenarios...
December 2, 2016: American Journal of Infection Control
https://www.readbyqxmd.com/read/27818427/improving-the-public-health-infrastructure-capacity-in-the-u-s-pacific-territories
#6
Stephanie A Dopson
The public health emergency of 2009 pandemic influenza A (H1N1) virus resulted in supplemental funding provided by Congress to the 62 states and territories. The CDC's response included deployment of personnel to the U.S. Pacific territories, who provided technical assistance on laboratory capacity, information technology, surveillance, planning, and continuity of operations.
2016: Journal of Health Care for the Poor and Underserved
https://www.readbyqxmd.com/read/27783613/voluntary-medical-male-circumcision-for-hiv-prevention-new-mathematical-models-for-strategic-demand-creation-prioritizing-subpopulations-by-age-and-geography
#7
Catherine Hankins, Mitchell Warren, Emmanuel Njeuhmeli
Over 11 million voluntary medical male circumcisions (VMMC) have been performed of the projected 20.3 million needed to reach 80% adult male circumcision prevalence in priority sub-Saharan African countries. Striking numbers of adolescent males, outside the 15-49-year-old age target, have been accessing VMMC services. What are the implications of overall progress in scale-up to date? Can mathematical modeling provide further insights on how to efficiently reach the male circumcision coverage levels needed to create and sustain further reductions in HIV incidence to make AIDS no longer a public health threat by 2030? Considering ease of implementation and cultural acceptability, decision makers may also value the estimates that mathematical models can generate of immediacy of impact, cost-effectiveness, and magnitude of impact resulting from different policy choices...
2016: PloS One
https://www.readbyqxmd.com/read/27771067/circulation-of-multiple-genotypes-of-h1n2-viruses-in-a-swine-farm-in-italy-over-a-two-month-period
#8
Maria Serena Beato, Luca Tassoni, Adelaide Milani, Annalisa Salviato, Guido Di Martino, Monica Mion, Lebana Bonfanti, Isabella Monne, Simon James Watson, Alice Fusaro
In August 2012 repeated respiratory outbreaks caused by swine influenza A virus (swIAV) were registered for a whole year in a breeding farm in northeast Italy that supplied piglets for fattening. The virus, initially characterized in the farm, was a reassortant Eurasian avian-like H1N1 (H1avN1) genotype, containing a haemagglutinin segment derived from the pandemic H1N1 (A(H1N1)pdm09) lineage. To control infection, a vaccination program using vaccines against the A(H1N1)pdm09, human-like H1N2 (H1huN2), human-like H3N2 (H3N2), and H1avN1 viruses was implemented in sows in November 2013...
November 15, 2016: Veterinary Microbiology
https://www.readbyqxmd.com/read/27756233/school-closure-policies-at-municipality-level-for-mitigating-influenza-spread-a-model-based-evaluation
#9
Constanze Ciavarella, Laura Fumanelli, Stefano Merler, Ciro Cattuto, Marco Ajelli
BACKGROUND: Nearly every year Influenza affects most countries worldwide and the risk of a new pandemic is always present. Therefore, influenza is a major concern for public health. School-age individuals are often the most affected group, suggesting that the inclusion in preparedness plans of school closure policies may represent an option for influenza mitigation. However, their applicability remains uncertain and their implementation should carefully be weighed on the basis of cost-benefit considerations...
October 18, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27733236/risk-of-resistant-avian-influenza-a-virus-in-wild-waterfowl-as-a-result-of-environmental-release-of-oseltamivir
#10
Anna Gillman
Oseltamivir is the best available anti-influenza drug and has therefore been stockpiled worldwide in large quantities as part of influenza pandemic preparedness planning. The active metabolite oseltamivir carboxylate (OC) is stable and is not removed by conventional sewage treatment. Active OC has been detected in river water at concentrations up to 0.86 µg/L. Although the natural reservoir hosts of influenza A virus (IAV) are wild waterfowl that reside in aquatic environments, the ecologic risks associated with environmental OC release and its potential to generate resistant viral variants among wild birds has largely been unknown...
2016: Infection Ecology & Epidemiology
https://www.readbyqxmd.com/read/27724915/reducing-disease-burden-in-an-influenza-pandemic-by-targeted-delivery-of-neuraminidase-inhibitors-mathematical-models-in-the-australian-context
#11
Robert Moss, James M McCaw, Allen C Cheng, Aeron C Hurt, Jodie McVernon
BACKGROUND: Many nations maintain stockpiles of neuraminidase inhibitor (NAI) antiviral agents for use in influenza pandemics to reduce transmission and mitigate the course of clinical infection. Pandemic preparedness plans include the use of these stockpiles to deliver proportionate responses, informed by emerging evidence of clinical impact. Recent uncertainty about the effectiveness of NAIs has prompted these nations to reconsider the role of NAIs in pandemic response, with implications for pandemic planning and for NAI stockpile size...
October 10, 2016: BMC Infectious Diseases
https://www.readbyqxmd.com/read/27686834/integrating-pharmacies-into-public-health-program-planning-for-pandemic-influenza-vaccine-response
#12
Thomas J Fitzgerald, Yoonjae Kang, Carolyn B Bridges, Todd Talbert, Sara J Vagi, Brock Lamont, Samuel B Graitcer
BACKGROUND: During an influenza pandemic, to achieve early and rapid vaccination coverage and maximize the benefit of an immunization campaign, partnerships between public health agencies and vaccine providers are essential. Immunizing pharmacists represent an important group for expanding access to pandemic vaccination. However, little is known about nationwide coordination between public health programs and pharmacies for pandemic vaccine response planning. METHODS: To assess relationships and planning activities between public health programs and pharmacies, we analyzed data from Centers for Disease Control and Prevention assessments of jurisdictions that received immunization and emergency preparedness funding from 2012 to 2015...
September 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27646029/stakeholders-perceptions-of-10years-of-the-global-action-plan-for-influenza-vaccines-gap-results-from-a-survey
#13
Claudia Nannei, Shoshanna Goldin, Guido Torelli, Hiba Fatima, Kaveri Kumar, Oliver Bubb-Humfryes, Bo Stenson, Erin Sparrow
Ten years after the launch of the Global Action Plan for Influenza Vaccines (GAP), the World Health Organization (WHO) surveyed stakeholders to understand their perceptions of what the programme had achieved. This article provides a summary of the findings; the full report will be available on-line on the GAP website in November 2016 (http://www.who.int/influenza_vaccines_plan/en/). Seventy-seven responses were received from stakeholders including medical doctors, national influenza center officials, country immunization programme teams, surveillance and disease centers, policy-makers, researchers, vaccine manufacturers, and non-governmental organizations from 28 countries, representing all six WHO regions...
October 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27622299/passive-immunization-for-influenza-through-antibody-therapies-a-review-of-the-pipeline-challenges-and-potential-applications
#14
Erin Sparrow, Martin Friede, Mohamud Sheikh, Siranda Torvaldsen, Anthony T Newall
The Global Action Plan for influenza vaccines (GAP) aims to increase the production capacity of vaccines so that in the event of a pandemic there is an adequate supply to meet global needs. However, it has been estimated that even in the best case scenario there would be a considerable delay of at least five to six months for the first supplies of vaccine to become available after the isolation of the strain and availability of the candidate vaccine virus to vaccine manufacturers. By this time, the virus is likely to have already infected millions of people worldwide, causing significant mortality, morbidity and economic loss...
October 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27593158/development-and-approval-of-live-attenuated-influenza-vaccines-based-on-russian-master-donor-viruses-process-challenges-and-success-stories
#15
Larisa Rudenko, Leena Yeolekar, Irina Kiseleva, Irina Isakova-Sivak
Influenza is a viral infection that affects much of the global population each year. Vaccination remains the most effective tool for preventing the disease. Live attenuated influenza vaccine (LAIV) has been used since the 1950s to protect humans against seasonal influenza. LAIVs developed by the Institute of Experimental Medicine (IEM), Saint Petersburg, Russia, have been successfully used in Russia since 1987. In 2006, the World Health Organization (WHO) announced a Global action plan for influenza vaccines (GAP)...
October 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27545901/pandemic-risk-assessment-model-pram-a-mathematical-modeling-approach-to-pandemic-influenza-planning
#16
D C Dover, E M Kirwin, N Hernandez-Ceron, K A Nelson
The Pandemic Risk Assessment Model (PRAM) is a mathematical model developed to analyse two pandemic influenza control measures available to public health: antiviral treatment and immunization. PRAM is parameterized using surveillance data from Alberta, Canada during pandemic H1N1. Age structure and risk level are incorporated in the compartmental, deterministic model through a contact matrix. The model characterizes pandemic influenza scenarios by transmissibility and severity properties. Simulating a worst-case scenario similar to the 1918 pandemic with immediate stockpile release, antiviral demand is 20·3% of the population...
August 22, 2016: Epidemiology and Infection
https://www.readbyqxmd.com/read/27531411/the-2015-global-production-capacity-of-seasonal-and-pandemic-influenza-vaccine
#17
Kenneth A McLean, Shoshanna Goldin, Claudia Nannei, Erin Sparrow, Guido Torelli
A global shortage and inequitable access to influenza vaccines has been cause for concern for developing countries who face dire consequences in the event of a pandemic. The Global Action Plan for Influenza Vaccines (GAP) was launched in 2006 to increase global capacity for influenza vaccine production to address these concerns. It is widely recognized that well-developed infrastructure to produce seasonal influenza vaccines leads to increased capacity to produce pandemic influenza vaccines. This article summarizes the results of a survey administered to 44 manufacturers to assess their production capacity for seasonal influenza and pandemic influenza vaccine production...
October 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27506497/challenges-and-successes-for-the-grantees-and-the-technical-advisory-group-of-who-s-influenza-vaccine-technology-transfer-initiative
#18
Gary Grohmann, Donald P Francis, Jaspal Sokhey, James Robertson
One of the aims of the WHO Global Action Plan for Influenza Vaccines (GAP) was to transfer influenza vaccine production technology to interested manufacturers and governments in developing countries, to enable greater influenza vaccine manufacturing capacity against any pandemic threat or pandemic. For this objective, the GAP was supported by an independent Technical Advisory Group (TAG) to assist WHO to select vaccine manufacturing proposals for funding and to provide programmatic support for successful grantees...
October 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27498212/a-decade-of-adaptation-regulatory-contributions-of-the-world-health-organization-to-the-global-action-plan-for-influenza-vaccines-2006-2016
#19
Laszlo Palkonyay, Hiba Fatima
The Global Action Plan (GAP) for Influenza Vaccines is a decade-long initiative that brings together a diverse range of stakeholders to work towards reducing anticipated global shortage of influenza vaccines and ensuring more equitable access to vaccines during the next influenza pandemic. Since its inception in 2006, significant progress has been made towards all the main objectives of GAP, namely: (1) an increase in seasonal vaccine use, (2) an increase in vaccine production, and (3) progress in research and development of more effective vaccines...
October 26, 2016: Vaccine
https://www.readbyqxmd.com/read/27484011/chemistry-manufacturing-and-control-cmc-and-clinical-trial-technical-support-for-influenza-vaccine-manufacturers
#20
Rahnuma Wahid, Renee Holt, Richard Hjorth, Francesco Berlanda Scorza
With the support of the Biomedical Advanced Research and Development Authority (BARDA) of the US Department of Health and Human Services, PATH has contributed to the World Health Organization's (WHO's) Global Action Plan for Influenza Vaccines (GAP) by providing technical and clinical assistance to several developing country vaccine manufacturers (DCVMs). GAP builds regionally based independent and sustainable influenza vaccine production capacity to mitigate the overall global shortage of influenza vaccines...
October 26, 2016: Vaccine
keyword
keyword
56730
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"