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https://www.readbyqxmd.com/read/29241967/survey-of-the-american-pediatric-surgical-association-on-cannulation-practices-in-pediatric-ecmo
#1
Alejandro V Garcia, Maniraj Jeyaraju, Mitchell R Ladd, Eric B Jelin, Melania M Bembea, Samuel Alaish, Daniel Rhee
AIMS: Extracorporeal membrane oxygenation (ECMO) is a commonly used modality of life support for children with cardiopulmonary failure. Consensus on pediatric cannulation strategies and management does not currently exist. The goal of this study was to investigate individual surgeon approaches towards ECMO cannulations in children. METHODS: A 21-question online survey was developed and disseminated to the American Pediatric Surgical Association (APSA) membership...
November 21, 2017: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29241440/primary-care-mental-health-integration-in-the-va-shifting-mental-health-services-for-common-mental-illnesses-to-primary-care
#2
Lucinda B Leung, Jean Yoon, José J Escarce, Edward P Post, Kenneth B Wells, Catherine A Sugar, Elizabeth M Yano, Lisa V Rubenstein
OBJECTIVE: Primary care-mental health integration (PC-MHI) aims to increase access to general mental health specialty (MHS) care for primary care patients thereby decreasing referrals to non-primary care-based MHS services. It remains unclear whether new patterns of usage of MHS services reflect good mental health care. This study examined the relationship between primary care clinic engagement in PC-MHI and use of different MHS services. METHODS: This was a retrospective longitudinal cohort study of 66,638 primary care patients with mental illnesses in 29 Southern California Veterans Affairs clinics (2008-2013)...
December 15, 2017: Psychiatric Services: a Journal of the American Psychiatric Association
https://www.readbyqxmd.com/read/29241322/modulatory-effects-of-dietary-supplementation-by-vernonia-amygdalina-on-high-fat-diet-induced-obesity-in-wistar-rats
#3
Chima A Ekeleme-Egedigwe, Ifeoma I Ijeh, Polycarp N Okafor
BACKGROUND: Obesity is a growing public health problem arising from energy imbalance. The effect of 10% dietary incorporation of Vernonia amygdalina (VA) leaves into high-fat diets on some biological markers of adiposity and dyslipidaemia was investigated. METHODS: Experimental diets consisted of the following – CD (control diet); HFD (high-fat diet); and HFD- VA (HFD containing 10% Vernonia amygdalina leaves) supplementation. Fifteen male Wistar rats were randomly divided into three groups of five animals each...
October 2017: Acta Scientiarum Polonorum. Technologia Alimentaria
https://www.readbyqxmd.com/read/29240306/diabetic-macular-oedema-treated-with-intravitreal-anti-vascular-endothelial-growth-factor-2-4%C3%A2-years-follow-up-of-visual-acuity-and-retinal-thickness-in-566-patients-following-danish-national-guidelines
#4
Delila Hodzic-Hadzibegovic, Birgit Agnes Sander, Tine Juul Monberg, Michael Larsen, Henrik Lund-Andersen
PURPOSE: To investigate long-term functional and anatomical outcomes, discontinuation patterns, drug switching and rates of nonimprovement in patients treated with ranibizumab pro re nata (PRN) regimen for diabetic macular oedema (DME) according to the Danish national guidelines. METHODS: Retrospective cohort study of 566 eyes in 566 patients with centre-involved DME who started intravitreal treatment with ranibizumab between January 2011 and December 2013 in the Greater Copenhagen region...
December 14, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29240299/the-effect-of-haemopoietic-stem-cell-transplantation-on-the-ocular-phenotype-in-mucopolysaccharidosis-type-i-hurler
#5
Ahmed Javed, Tariq Aslam, Simon A Jones, Jean Mercer, Karen Tyler, Heather Church, Arunabha Ghosh, Robert Wynn, Krishanthy Sornalingam, Jane Ashworth
PURPOSE: To determine whether the ocular phenotype in patients with mucopolysaccharidosis type I (MPSI) Hurler is affected by the efficacy of previous haemopoietic stem cell transplantation (HSCT). DESIGN: A retrospective cohort study of patients with MPSI who had undergone treatment with HSCT. METHODS: Ocular phenotype was documented for each patient and compared to levels of biomarkers representing efficacy of previous transplantation. MAIN OUTCOME MEASURES: Assessment of visual acuity (VA), severity of corneal clouding and the presence of optic neuropathy or retinopathy...
December 14, 2017: Acta Ophthalmologica
https://www.readbyqxmd.com/read/29239561/spatial-analysis-of-cutaneous-leishmaniasis-in-an-endemic-area-of-iran-based-on-environmental-factors
#6
Roghieh Ramezankhani, Nooshin Sajjadi, Roya Nezakati Esmaeilzadeh, Seyed Ali Jozi, Mohammad Reza Shirzadi
Leishmaniasis is a parasitic disease caused by different species of protozoan parasites. Cutaneous leishmaniasis (CL) is still a great public health problem in Iran, especially in Isfahan Province. Distribution and abundance of vectors and reservoirs of this disease is affected by different factors such as climatic, socioeconomic and cultural. This study aimed to identify the hotspot areas for CL in Isfahan and assess the relations between the climatic and topographic factors with CL incidence using spatial analysis...
November 8, 2017: Geospatial Health
https://www.readbyqxmd.com/read/29239024/concordance-between-administrative-data-and-clinical-review-for-mortality-in-the-randomized-on-off-bypass-follow-up-study-rooby-fs
#7
Jacquelyn A Quin, Brack Hattler, Annie Laurie W Shroyer, Darlene Kemp, G Hossein Almassi, Faisal G Bakaeen, Brendan M Carr, Muath Bishawi, Joseph F Collins, Frederick L Grover, Todd H Wagner
BACKGROUND: The optimal methodology to identify cardiac versus non-cardiac cause of death following cardiac surgery has not been determined. METHODS: The Randomized On/Off Bypass Trial was a multicenter, randomized, controlled clinical trial of 2203 patients (February 2002-May 2008) comparing 1-year cardiac outcomes between off-pump and on-pump bypass surgery. In 2013, the Veterans Affairs (VA) Cooperative Studies Program funded a follow-up study to assess 5-year outcomes including mortality...
December 13, 2017: Journal of Cardiac Surgery
https://www.readbyqxmd.com/read/29238609/blunted-heart-rate-recovery-is-associated-with-coronary-artery-spasm-in-patients-with-suspected-vasospastic-angina
#8
Hyunsu Kim, Sang-Hoon Cho, Kyoung-Im Cho, Bong-Joon Kim, Sung-Il Im, Jung-Ho Heo
Background: Autonomic nervous system activity has been shown to be altered in patients with vasospastic angina (VA). Heart rate recovery (HRR) is a simple, non-invasive measurement of autonomic nervous system dysfunction. We aimed to investigate whether HRR is related to VA, as established by an ergonovine test. Methods: A total of 976 consecutive patients (47.5% male, mean age 55 years) without significant coronary artery disease who underwent both an ergonovine provocation test and a treadmill exercise test were enrolled...
2017: Clinical Hypertension
https://www.readbyqxmd.com/read/29237435/clinical-safety-of-combined-therapy-of-immune-checkpoint-inhibitors-and-viscum-album-l-therapy-in-patients-with-advanced-or-metastatic-cancer
#9
Anja Thronicke, Megan L Steele, Christian Grah, Burkhard Matthes, Friedemann Schad
BACKGROUND: Despite improvement of tumour response rates in patients with progressive and metastatic cancer, immune checkpoint inhibitors (ICM) induce toxicities in cancer patients. Viscum album L. (VA, mistletoe) extracts are applied as add-on cancer therapy especially in German speaking countries and within integrative and anthroposophical concepts with the goal to improve quality of life. The primary objective of this pilot observational cohort study was to determine the rate of adverse events (AE) related to ICM therapy with and without VA in patients with advanced or metastatic cancer in a certified Cancer Center...
December 13, 2017: BMC Complementary and Alternative Medicine
https://www.readbyqxmd.com/read/29237145/current-practices-in-the-management-of-congenital-diaphragmatic-hernia-patients-requiring-extracorporeal-membrane-oxygenation-results-of-an-international-survey-of-pediatric-surgeons
#10
Sophia Abdulhai, Ian C Glenn, Neil L McNinch, Todd A Ponsky, Avraham Schlager
INTRODUCTION: There is little consensus on optimal management for congenital diaphragmatic hernia extracorporeal membrane oxygenation (CDH ECMO) patients. Meaningful comparisons of the various approaches have been limited due to the low number of cases in institutions. In addition, the multidisciplinary reliance and rigid institutional framework of ECMO serve to further limit exposure to alternative practices. The goal of this study is to survey the international pediatric surgery community to describe the current practice trends...
December 13, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/29233710/magnetic-field-driven-drug-release-from-modified-iron-oxide-integrated-polysaccharide-hydrogel
#11
Xinyu Hu, Yongmei Wang, Liangliang Zhang, Man Xu, Jianfa Zhang, Wei Dong
Salecan is a novel water-soluble extracellular β-glucan and suitable for the hydrogel preparation due to its excellent physicochemical and biological properties. The present article describes the fabrication and characterization of a pH/magnetic field-driven hydrogel based on salecan-g-poly(vinylacetic acid-co-2-hydroxyethyl acrylate) [poly(VA-co-HEA)] copolymer and Fe3O4@Agarose nanoparticles for drug release testing. Vibrating sample magnetometer characterization verified that integration of Fe3O4@Agarose nanoparticles in the copolymer provided the sensitivity to magnetic fields...
December 9, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29232892/new-three-dimensional-porous-electrode-concept-vertically-aligned-carbon-nanotubes-directly-grown-on-embroidered-copper-structures
#12
Noemí Aguiló-Aguayo, Roger Amade, Shahzad Hussain, Enric Bertran, Thomas Bechtold
New three-dimensional (3D) porous electrode concepts are required to overcome limitations in Li-ion batteries in terms of morphology (e.g., shapes, dimensions), mechanical stability (e.g., flexibility, high electroactive mass loadings), and electrochemical performance (e.g., low volumetric energy densities and rate capabilities). Here a new electrode concept is introduced based on the direct growth of vertically-aligned carbon nanotubes (VA-CNTs) on embroidered Cu current collectors. The direct growth of VA-CNTs was achieved by plasma-enhanced chemical vapor deposition (PECVD), and there was no application of any post-treatment or cleaning procedure...
December 11, 2017: Nanomaterials
https://www.readbyqxmd.com/read/29232757/-real-life-data-on-the-treatment-of-diabetic-macular-oedema-in-germany
#13
Robert G H Wilke, Robert Patrick Finger, Helmut G Sachs
Background Controlled prospective clinical trials on the treatment of diabetic macular oedema (DME) using anti-VEGF compounds show very good results in visual acuity gain over several years. To date, only limited data are available from comparable studies under real-life settings in clinical routine. However, real-life data from other indications for anti-VEGF treatment suggest that, in clinical routine, gain in visual acuity is less pronounced and cannot be maintained over a longer period of time, which is related to the significantly lower number of injections administered in clinical routine...
December 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29232756/-the-conundrum-of-relationships-in-the-multivariate-dataset-of-nvamd-treatment
#14
Robert G H Wilke, Robert Patrick Finger, Helmut G Sachs
Background The evaluation of relationships in clinical case series is complicated by statistical pitfalls, one of which is spurious correlation. In this case, one or more potential factors are actually not related to a target measure, yet it may be wrongly inferred that they are. This may be due to either coincidence or the presence of a one or more confounding unregarded factors. In randomised clinical trials, it is attempted to eliminate such confounding factors or to control them by randomisation. However, this approach is not applicable in retrospective case series, and other statistical methods must be applied, such as multivariate analyses, taking into account all known variables...
December 2017: Klinische Monatsblätter Für Augenheilkunde
https://www.readbyqxmd.com/read/29232345/factors-associated-with-lack-of-vision-improvement-in-children-with-cortical-visual-impairment
#15
Swati Handa, Seyed E Saffari, Mark Borchert
BACKGROUND: Improvement in vision has been noted in children with cortical visual impairment (CVI), resulting from disparate types of brain injury. The purpose of our study was to determine the risk factors associated with poor recovery of vision in this group of patients. METHODS: Case records of children who were born before 2010 with at least 4 follow-up visits for CVI were reviewed for underlying etiologies of CVI, visual acuity (VA), and associated neurological and ophthalmological disorders...
December 8, 2017: Journal of Neuro-ophthalmology: the Official Journal of the North American Neuro-Ophthalmology Society
https://www.readbyqxmd.com/read/29232075/extra-schedular-evaluations-for-individual-disabilities-final-rule
#16
(no author information available yet)
The Department of Veterans Affairs (VA) amends its adjudication regulation pertaining to extra-schedular consideration of a service-connected disability in exceptional compensation cases. This rule clarifies that an extra-schedular evaluation is to be applied to an individual service-connected disability when the disability is so exceptional or unusual that it makes application of the regular rating schedule impractical. An extra-schedular evaluation may not be based on the combined effect of more than one service-connected disability...
December 8, 2017: Federal Register
https://www.readbyqxmd.com/read/29231668/ecclesiastical-endorsing-organizations-final-rule
#17
(no author information available yet)
The Department of Veterans Affairs (VA) is amending its medical regulations by establishing in regulation the eligibility requirements that ecclesiastical endorsing organizations must meet in order to provide ecclesiastical endorsements of individuals seeking employment as VA chaplains, or of individuals who are seeking to be engaged by VA under contract or appointed as on-facility fee basis VA chaplains under the United States Code. VA considers veterans' spiritual care an integral part of their overall health care...
November 8, 2017: Federal Register
https://www.readbyqxmd.com/read/29231129/-i-think-it-s-pretty-much-the-same-as-it-should-be-perspectives-of-inpatient-care-among-women-veterans
#18
Andrea M Shamaskin-Garroway, M Tish Knobf, Lynette J Adams, Sally G Haskell
The purpose of this study was to gain a deeper understanding of the inpatient hospitalization experience for women veterans through in-depth interviews. Women veterans who were admitted for inpatient care on medical units within a university-affiliated VA hospital were invited to participate in a semistructured interview that inquired about their hospital experience, interactions with medical providers, and how being a woman veteran might affect this experience. Interviews were transcribed verbatim and analyzed using constant comparative method until thematic saturation was achieved ( n = 25)...
December 1, 2017: Qualitative Health Research
https://www.readbyqxmd.com/read/29229519/leptin-injection-into-the-left-stellate-ganglion-augments-ischemia-related-ventricular-arrhythmias-via-sympathetic-nerve-activation
#19
Lilei Yu, Yuhong Wang, Xiaoya Zhou, Bing Huang, Menglong Wang, Xuefei Li, Guannan Meng, Shenxu Yuan, Hao Xia, Hong Jiang
BACKGROUND: Leptin is a peptide hormone produced by adipose tissue whose basic function is regulating energy balance and sympathetic outflow. Previous studies have shown that increased nerve activity of the left stellate ganglion (LSG) promotes ventricular arrhythmia (VA). OBJECTIVE: The aim of this study is to investigate whether leptin could facilitate VA through the activation of LSG. METHODS: Sixteen pentobarbital-anesthetized dogs were divided into a control group (saline, n=8) and a leptin group (leptin, n=8)...
December 8, 2017: Heart Rhythm: the Official Journal of the Heart Rhythm Society
https://www.readbyqxmd.com/read/29229437/the-epidemiology-of-hip-fractures-across-western-victoria-australia
#20
Kara L Holloway, Muhammad A Sajjad, Mohammadreza Mohebbi, Mark A Kotowicz, Patricia M Livingston, Mustafa Khasraw, Sharon Hakkennes, Trisha L Dunning, Susan Brumby, Richard S Page, Daryl Pedler, Alasdair Sutherland, Svetha Venkatesh, Sharon L Brennan-Olsen, Lana J Williams, Julie A Pasco
BACKGROUND: Hip fractures are associated with considerable morbidity and mortality. Hip fracture incidence varies across different levels of accessibility/remoteness and socioeconomic status (SES). As part of the Ageing, Chronic Disease and Injury Study, we aimed to map the pattern of hip fractures across the western region of the Australian state of Victoria, which contains a range of remoteness levels and SES. METHODS: Data on hip fractures resulting in hospital admission were extracted from the Victorian Admitted Episodes Dataset (VAED) for men and women aged 40+years during 2010-2013 inclusive...
December 8, 2017: Bone
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