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https://www.readbyqxmd.com/read/28445910/influence-of-contrast-media-on-bone-mineral-density-bmd-measurements-from-routine-contrast-enhanced-mdct-datasets-using-a-phantom-less-bmd-measurement-tool
#1
Andrea Toelly, Constanze Bardach, Michael Weber, Rui Gong, Yanbo Lai, Pei Wang, Yulin Guo, Jan Kirschke, Thomas Baum, Michael Gruber
Aim To evaluate the differences in phantom-less bone mineral density (BMD) measurements in contrast-enhanced routine MDCT scans at different contrast phases, and to develop an algorithm for calculating a reliable BMD value. Materials and Methods 112 postmenopausal women from the age of 40 to 77 years (mean age: 57.31 years; SD 9.61) who underwent a clinically indicated MDCT scan, consisting of an unenhanced, an arterial, and a venous phase, were included. A retrospective analysis of the BMD values of the Th12 to L4 vertebrae in each phase was performed using a commercially available phantom-less measurement tool...
April 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28445909/transient-severe-motion-artifact-related-to-gadoxetate-disodium-enhanced-liver-mri-frequency-and-risk-evaluation-at-a-german-institution
#2
Lennart Well, Vanessa Hanna Rausch, Gerhard Adam, Frank Oliver Henes, Peter Bannas
Purpose Varying frequencies (5 - 18 %) of contrast-related transient severe motion (TSM) imaging artifacts during gadoxetate disodium-enhanced arterial phase liver MRI have been reported. Since previous reports originated from the United States and Japan, we aimed to determine the frequency of TSM at a German institution and to correlate it with potential risk factors and previously published results. Materials and Methods Two age- and sex-matched groups were retrospectively selected (gadoxetate disodium n = 89; gadobenate dimeglumine n = 89) from dynamic contrast-enhanced MRI examinations in a single center...
April 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28445908/diagnosis-of-pulmonary-artery-embolism-comparison-of-single-source-ct-and-3rd-generation-dual-source-ct-using-a-dual-energy-protocol-regarding-image-quality-and-radiation-dose
#3
Bernhard Petritsch, Aleksander Kosmala, Tobias Gassenmaier, Andreas Max Weng, Simon Veldhoen, Andreas Steven Kunz, Thorsten Alexander Bley
Purpose To compare radiation dose, subjective and objective image quality of 3 rd generation dual-source CT (DSCT) and dual-energy CT (DECT) with conventional 64-slice single-source CT (SSCT) for pulmonary CTA. Materials and Methods 180 pulmonary CTA studies were performed in three patient cohorts of 60 patients each. Group 1: conventional SSCT 120 kV (ref.); group 2: single-energy DSCT 100 kV (ref.); group 3: DECT 90/Sn150 kV. CTDIvol, DLP, effective radiation dose were reported, and CT attenuation (HU) was measured on three central and peripheral levels...
April 26, 2017: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/28445906/-bipolar-stimulation-may-improve-the-efficacy-of-the-percutaneous-nerve-evaluation-test-of-sacral-neuromodulation
#4
André Reitz, Tanja Hüsch, Regula Doggweiler, Stephan Buse, Axel Haferkamp
Purpose This study evaluates the hypothesis that bipolar stimulation of the S3 and S4 sacral roots may enhance the efficacy of the percutaneous nerve evaluation (PNE) test. Material and Methods In this case-control-study, we enrolled 43 patients undergoing bipolar PNE and 57 controls undergoing unipolar PNE. For bipolar PNE, four test electrodes were placed at the bilateral S3 and S4 roots. The electrodes at the S3 and S4 roots of each side were connected to obtain bipolar stimulation. The test protocol over eight days included unilateral and bilateral stimulation of the S3 and S4 sacral roots...
April 26, 2017: Aktuelle Urologie
https://www.readbyqxmd.com/read/28445902/a-3d-printed-cap-with-sideoptics-for-colonoscopy-a-randomized-ex-vivo-study
#5
Benjamin M Walter, Alexander Hann, Rena Frank, Alexander Meining
Background Adequate polyp detection is crucial to colonoscopy; however, detection can be impaired. In particular, flat polyps located behind folds or near the colonic flexures appear to be a problem. We present a cheap and easily adjustable 3D-printed tool to enhance the view of a standard colonoscope using additional commercially available sideoptics. Materials and methods A cap adjustable to a standard endoscope was printed by a 3 D printer and had two microcameras fixed to offer two additional views...
April 26, 2017: Endoscopy
https://www.readbyqxmd.com/read/28445861/the-application-of-silicon-sol-gel-technology-to-forensic-blood-substitute-development-investigation-of-the-spreading-dynamics-onto-a-paper-surface
#6
Theresa Stotesbury, Mike Illes, Paul Wilson, Andrew J Vreugdenhil
This work investigates the spreading dynamics of three candidate sol-gel solutions, of ranging viscosities, surface tensions and densities, and compares them with water and two commercial blood substitute products. Droplets were created with different sizes (10 to75μL) and impact velocities (1.4 to 6.0m/s) to strike 176gsm cardstock. Over 2200 droplets were created using the six different fluids and their final dried stain diameter was measured. Droplet spread was plotted using the Scheller and Bousfield correlation and uses effective viscosity as a parameter for non-Newtonian fluids...
April 1, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28445860/brephedrone-a-new-psychoactive-substance-seized-in-brazil
#7
Yuri Machado, José Coelho Neto, Paulo Eduardo Nunes Barbosa, Rogério Araújo Lordeiro, Rosemeire Brondi Alves
At the beginning of 2015, sixty-two capsules containing red-brown crystals seized in a historical city in Brazil were sent to this forensic laboratory for drug testing analysis. The material was identified as being Brephedrone, a new psychoactive substance and a bromine synthetic cathinone that is related to serotonin transportation. This substance was analyzed by ATR-FTIR, GC-MS, LC-MS, (1)H, (13)C and 2D NMR. Brephedrone apprehensions have been previously reported in Finland, France and Spain. It was the first detection of this substance in the State of Minas Gerais...
April 15, 2017: Forensic Science International
https://www.readbyqxmd.com/read/28445849/a-reference-measurement-procedure-for-amino-acids-in-blood-using-isotope-dilution-ultra-performance-liquid-chromatography-tandem-mass-spectrometry
#8
Juok Kim, Tran Thi Thanh Huong, Seon-Pyo Hong, Ji-Seon Jeong
We described a reference measurement procedure for amino acid (AA) quantification in blood samples based on deproteinization with 5-sulfosalicylic acid (SSA) and an isotope dilution-ultra performance liquid chromatography-tandem mass spectrometry (LC-MS) method. The serum was deproteinized with 15% v/v SSA and the supernatant was injected directly into the LC-MS system without further processing. Compared with the use of other precipitants and water as a control, five model AAs-valine, isoleucine, leucine, tyrosine, and phenylalanine-in the SSA-treated samples showed ionization enhancement as well as stable background signals without significant ion suppression effects...
April 17, 2017: Journal of Chromatography. B, Analytical Technologies in the Biomedical and Life Sciences
https://www.readbyqxmd.com/read/28445845/the-capacity-and-effectiveness-of-diosmectite-and-charcoal-in-trapping-the-compounds-causing-the-most-frequent-intoxications-in-acute-medicine-a-comparative-study
#9
Michaela Mináriková, Veronika Fojtikova, Eliška Vyskočilová, Jan Sedláček, Milan Šikut, Lucie Borek-Dohalska, Marie Stiborová, Marketa Martinkova
The aim of the study was to compare the adsorption ability of two adsorbent materials, namely diosmectite and activated charcoal towards selected model compounds that are most commonly involved in acute intoxication. Eleven model compounds were selected: acetylsalicylic acid, α-amanitin, amlodipine, digoxin, phenobarbital, ibuprofen, imipramine, carbamazepine, oxazepam, promethazine, and theophylline. Of the tested compounds, promethazine and imipramine were the most effectively adsorbed to diosmectite. Their adsorption to diosmectite (0...
April 17, 2017: Environmental Toxicology and Pharmacology
https://www.readbyqxmd.com/read/28445823/engineering-metal-hydr-oxide-sorbents-for-removal-of-arsenate-and-similar-weak-acid-oxyanion-contaminants-a-critical-review-with-emphasis-on-factors-governing-sorption-processes
#10
Kiril D Hristovski, Jasmina Markovski
To create an integrative foundation for engineering of the next generation inexpensive sorbent systems, this critical review addresses the existing knowledge gap in factor/performance relationships between weak-acid oxyanion contaminants and metal (hydr)oxide sorbents. In-depth understanding of fundamental thermodynamics and kinetics mechanisms, material fabrication, and analytical and characterization techniques, is necessary to engineer sorbent that exhibit high capacity, selectivity, stability, durability and mass transport of contaminants under a wide range of operating and water matrix conditions requirements...
April 22, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28445820/the-synthesis-and-properties-of-linear-a-%C3%AF-d-%C3%AF-a-type-organic-small-molecule-containing-diketopyrrolopyrrole-terminal-units
#11
Shanshan Zhang, Qingfen Niu, Tao Sun, Yang Li, Tianduo Li, Haixia Liu
A novel linear A-π-D-π-A-type organic small molecule Ph2(PDPP)2 consisting diketopyrrolopyrrole (DPP) as acceptor unit, biphenylene as donor unit and acetylene unit as π-linkage has been successfully designed and synthesized. Its corresponding thermal, photophysical and electrochemical properties as well as the photoinduced charge-separation process were investigated. Ph2(PDPP)2 exhibits high thermal stability and it can be soluble in common organic solvents such as chloroform and tetrahydrofuran. The photophysical properties show that DPP2Ph2 harvests sunlight over the entire visible spectrum range in the thin-film state (300-800nm)...
April 20, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28445814/comprehensive-profiling-and-characterization-of-coumarins-from-roots-stems-leaves-branches-and-seeds-of-chimonanthus-nitensoliv-using-ultra-performance-liquid-chromatography-quadrupole-time-of-flight-mass-spectrometry-combined-with-modified-mass-defect-filter
#12
Ting Tan, Yun Luo, Chen-Cong Zhong, Xu Xu, Yulin Feng
Chimonanthus nitensOliv. (CNO), having been studied and developed as the tea beverages, tea raw materials and preparations, an unique species in China, have been extensively used for treating colds and influenza for centuries. In the present study, a method based on the modified mass defect filter (MDF) was firstly developed and validated for comprehensive profiling of coumarins in the different parts of CNO via ultra-performance liquid chromatography tandem quadrupole time-of-flight mass spectrometry (UPLC-QTOF/MS)...
April 17, 2017: Journal of Pharmaceutical and Biomedical Analysis
https://www.readbyqxmd.com/read/28445803/jetvalve-rapid-manufacturing-of-biohybrid-scaffolds-for-biomimetic-heart-valve-replacement
#13
Andrew K Capulli, Maximillian Y Emmert, Francesco S Pasqualini, Debora Kehl, Etem Caliskan, Johan U Lind, Sean P Sheehy, Sung Jin Park, Seungkuk Ahn, Benedikt Weber, Josue A Goss, Simon P Hoerstrup, Kevin Kit Parker
Tissue engineered scaffolds have emerged as a promising solution for heart valve replacement because of their potential for regeneration. However, traditional heart valve tissue engineering has relied on resource-intensive, cell-based manufacturing, which increases cost and hinders clinical translation. To overcome these limitations, in situ tissue engineering approaches aim to develop scaffold materials and manufacturing processes that elicit endogenous tissue remodeling and repair. Yet despite recent advances in synthetic materials manufacturing, there remains a lack of cell-free, automated approaches for rapidly producing biomimetic heart valve scaffolds...
April 18, 2017: Biomaterials
https://www.readbyqxmd.com/read/28445683/impact-of-preoperative-breast-mr-imaging-and-mr-guided-surgery-on-diagnosis-and-surgical-outcome-of-women-with-invasive-breast-cancer-with-and-without-dcis-component
#14
Christiane K Kuhl, Kevin Strobel, Heribert Bieling, Eva Wardelmann, Walther Kuhn, Nikolaus Maass, Simone Schrading
Purpose To (a) compare the diagnostic accuracy of breast magnetic resonance (MR) imaging with that of conventional imaging (digital mammography and breast ultrasonography) in the identification of ductal carcinoma in situ (DCIS) components of biopsy-proven invasive breast cancer before surgery and (b) investigate the surgical outcome (positive margin rates and mastectomy rates) of women with breast cancer who underwent preoperative MR imaging combined with MR-guided needle biopsy and/or MR-guided lesion localization or bracketing where appropriate...
April 26, 2017: Radiology
https://www.readbyqxmd.com/read/28445682/atrial-fibrillation-diagnostic-accuracy-of-coronary-ct-angiography-performed-with-a-whole-heart-230-%C3%A2%C2%B5m-spatial-resolution-ct-scanner
#15
Daniele Andreini, Gianluca Pontone, Saima Mushtaq, Edoardo Conte, Marco Perchinunno, Marco Guglielmo, Valentina Volpato, Andrea Annoni, Andrea Baggiano, Alberto Formenti, Maria Elisabetta Mancini, Virginia Beltrama, Valentina Ditali, Alessandro Campari, Cesare Fiorentini, Antonio L Bartorelli, Mauro Pepi
Purpose To assess image quality, interpretability, diagnostic accuracy, and radiation exposure of a computed tomography (CT) scanner with 16-cm coverage and 230-µm spatial resolution at coronary artery evaluation in patients with atrial fibrillation (AF) by using invasive coronary angiography (ICA) as the reference method and to compare the results with those obtained in patients with sinus rhythm (SR). Materials and Methods Written informed consent and institutional ethics committee approval were obtained...
April 26, 2017: Radiology
https://www.readbyqxmd.com/read/28445645/simultaneous-ni-doping-at-atom-scale-in-ceria-and-assembling-into-well-defined-lotus-like-structure-for-enhanced-catalytic-performance
#16
Qingqing Li, Zhen Huang, Pengfei Guan, Rui Su, Qi Cao, Yimin Chao, Wei Shen, Junjie Guo, Hualong Xu, Renchao Che
Oxide materials with redox capability have attracted worldwide attentions in many applications. Introducing defects into crystal lattice is an effective method to modify and optimize redox capability of oxides as well as their catalytic performance. However, the relationship between intrinsic characteristics of defects and properties of oxides has been rarely reported. Herein, we report a facile strategy to introduce defects by doping a small amount of Ni atoms (1.8 at.%) into ceria lattice at atomic level through the effect of microstructure of crystal on the redox property of ceria...
April 26, 2017: ACS Applied Materials & Interfaces
https://www.readbyqxmd.com/read/28445641/exfoliation-of-lini1-3mn1-3co1-3o2-into-nanosheets-using-electrochemical-oxidation-and-reassembly-with-dialysis-or-flocculation
#17
Qian Cheng, Ting Yang, Man Li, Candace K Chan
Two-dimensional (2D) materials such as nanosheets are increasingly attracting attention for applications in energy storage and conversion. Many conventional battery compounds have layered structures, which can facilitate the exfoliation of these materials into nanosheet morphologies. In this work, LiNi1/3Mn1/3Co1/3O2 (NMC) particles were exfoliated into nanosheets using an electrochemical oxidation method enabled by the intercalation of tetraethylammonium cations into the interlayer space. The exfoliated materials were monolayer or double-layer nanosheets with hexagonal shapes and sizes < 50 nm...
April 26, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28445640/a-highly-active-and-stable-fe-n-c-catalyst-for-oxygen-depolarized-cathode-applications
#18
Jingkun Li, Qingying Jia, Shraboni Ghoshal, Wentao Liang, Sanjeev Mukerjee
Anion immunity towards oxygen reduction reaction (ORR) has tremendous implications in electrocatalysis with applications for fuel cells, metal-air batteries, and oxygen depolarized cathodes (ODCs) in anodic evolution of chlorine. The necessity for exploring ORR catalysts with immunity to anion adsorption is particularly significant considering that platinum group metal (PGM) catalysts are costly and highly vulnerable to impurities such as halides. Herein, we report a metal organic framework (MOF) derived Fe-N-C catalyst that exhibits a dramatically improved half-wave potential of 240 mV compared to the state-of-the-art RhxSy/C catalyst in a rotating disk electrode in the presence of Cl-...
April 26, 2017: Langmuir: the ACS Journal of Surfaces and Colloids
https://www.readbyqxmd.com/read/28445639/toward-covalent-organic-frameworks-bearing-three-different-kinds-of-pores-the-strategy-for-construction-and-cof-to-cof-transformation-via-heterogeneous-linker-exchange
#19
Cheng Qian, Qiao-Yan Qi, Guo-Fang Jiang, Fu-Zhi Cui, Yuan Tian, Xin Zhao
Covalent organic frameworks (COFs) are an emerging class of crystalline porous organic materials which are fabricated via reticular chemistry. Their topologic structures can be precisely predicted on the basis of the structures of building blocks. However, constructing COF with complicated structures has remained a great challenge, due to the limited strategies that can access to structural complexity of COFs. In this work, we have developed a new approach to produce COFs bearing three different kinds of pores...
April 26, 2017: Journal of the American Chemical Society
https://www.readbyqxmd.com/read/28445638/antigenic-gm3-lactone-mimetic-molecule-integrated-mannosylated-glycopeptide-nanofibers-for-the-activation-and-maturation-of-dendritic-cells
#20
Gokhan Gunay, Melis Sardan Ekiz, Xhenti Ferhati, Barbara Richichi, Cristina Nativi, Ayse Begum Tekinay, Mustafa O Guler
The ability of dendritic cells to coordinate innate and adaptive immune responses makes them essential targets for vaccination strategies. Presentation of specific antigens by dendritic cells is required for the activation of the immune system against many pathogens, and nanoscale materials can be functionalized for active targeting of dendritic cells. In this work, we integrated an immunogenic, carbohydrate melanoma-associated antigen-mimetic GM3-lactone molecule into mannosylated peptide amphiphile nanofibers to target dendritic cells through DC-SIGN receptor...
April 26, 2017: ACS Applied Materials & Interfaces
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