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Group a streptococcus

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https://www.readbyqxmd.com/read/28087956/intralesional-injection-of-ok-432-in-cystic-hygroma
#1
M Hazim, S S Moses, I P Tan
BACKGROUND: Lymphangiomas are congenital malformations of the lymphatic system with characteristic dilated endothelium-lined spaces. It is vulnerability to infection or chemical irritants cause spontaneous reduction in size and in some cases complete resolution. Intralesional injection of OK-432 or Picibanil (lyophilized incubation mixture of Group A Streptococcus pyogenes of human origin) is slowly gaining recognition as its safety and efficacy standards have shown to avoid complications resulting from surgical interventions...
December 2016: Medical Journal of Malaysia
https://www.readbyqxmd.com/read/28081323/acute-exudative-tonsillitis-in-adults-the-use-of-the-centor-scoreand-some-laboratory-tests
#2
Yavuz Furuncuoğlu, Filiz Sağlam, Ahmet Kutluhan
BACKGROUND/AIM: The aim of our study was to determine the usefulness of the Centor score and some basic laboratory tests (complete blood count and C-reactive protein) for the differential diagnosis of exudative tonsillitis due to Group A β-hemolytic streptococcus (GABHS) or due to non-GABHS agents. MATERIALS AND METHODS: The data of clinical and laboratory characteristics of the patients diagnosed with exudative tonsillitis were collected and statistically compared between those having positive GABHS throat culture result and those who were negative for any bacterial agent...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28077757/biotypes-and-scm-types-of-isolates-of-streptococcus-canis-from-diseased-and-healthy-cats
#3
J F Timoney, S Velineni, B Ulrich, P Blanchard
Lancefield group G Streptococcus canis is a component of the normal urogenital and pharyngeal flora of the cat. It is also frequently implicated in epizootics of severe disease in closed cat colonies and animal shelters. Given the importance of S canis as a feline pathogen and relative lack of published information on characteristics potentially associated with virulence, the authors have compared isolates from healthy and diseased cats in New York and California using fermentation profiles (biotype) and ScM sequences...
January 11, 2017: Veterinary Record
https://www.readbyqxmd.com/read/28077283/aetiology-of-febrile-pharyngitis-in-children-potential-of-myxovirus-resistance-protein-a-mxa-as-a-biomarker-of-viral-infection
#4
Lauri Ivaska, Jussi Niemelä, Johanna Lempainen, Riikka Österback, Matti Waris, Tytti Vuorinen, Jukka Hytönen, Kaisu Rantakokko-Jalava, Ville Peltola
OBJECTIVES: Besides group A streptococcus (GAS), microbial causes of pharyngitis in children are not well known. We aimed to document the viral and bacterial aetiology of pharyngitis and to assess the pathogenic role of viruses by determining the myxovirus resistance protein A (MxA) in the blood as a marker of interferon response. METHODS: In this prospective observational study, throat swabs and blood samples were collected from children (age 1-16 years) presenting to the emergency department with febrile pharyngitis...
January 7, 2017: Journal of Infection
https://www.readbyqxmd.com/read/28074049/in-vitro-antibacterial-activity-of-%C3%AE-methoxyimino-acylide-derivatives-against-macrolide-resistant-pathogens-and-mutation-analysis-in-23s-rrna
#5
Hiroyuki Sugiyama, Ippei Yoshida, Mayumi Ueki, Katsuhiko Tanabe, Akira Manaka, Keiichi Hiramatsu
We characterized in vitro activities of α-methoxyimino acylides against macrolide-resistant clinical isolates of Streptococcus pneumoniae, Streptococcus pyogenes and Mycoplasma pneumoniae with ribosome modification or substitution and selected acylide-resistant mutants to clarify the binding point of the acylides. The acylides had low MICs against erm(B) gene-containing S. pneumoniae and S. pyogenes (MIC90s, 1-4 μg ml(-1)). For M. pneumoniae, although they had poor potencies against macrolide-resistant strains with the A2058G (Escherichia coli numbering) mutation in 23S rRNA (MICs, >32 μg ml(-1)), one of them showed in vitro activities against macrolide-resistant strains with the A2058U or A2059G mutations (MICs, 0...
January 11, 2017: Journal of Antibiotics
https://www.readbyqxmd.com/read/28074024/whole-genome-sequencing-of-invasion-resistant-cells-identifies-laminin-%C3%AE-2-as-a-host-factor-for-bacterial-invasion
#6
Xander M van Wijk, Simon Döhrmann, Björn M Hallström, Shangzhong Li, Bjørn G Voldborg, Brandon X Meng, Karen K McKee, Toin H van Kuppevelt, Peter D Yurchenco, Bernhard O Palsson, Nathan E Lewis, Victor Nizet, Jeffrey D Esko
: To understand the role of glycosaminoglycans in bacterial cellular invasion, xylosyltransferase-deficient mutants of Chinese hamster ovary (CHO) cells were created using clustered regularly interspaced short palindromic repeat (CRISPR) and CRISPR-associated gene 9 (CRISPR-cas9) gene targeting. When these mutants were compared to the pgsA745 cell line, a CHO xylosyltransferase mutant generated previously using chemical mutagenesis, an unexpected result was obtained. Bacterial invasion of pgsA745 cells by group B Streptococcus (GBS), group A Streptococcus, and Staphylococcus aureus was markedly reduced compared to the invasion of wild-type cells, but newly generated CRISPR-cas9 mutants were only resistant to GBS...
January 10, 2017: MBio
https://www.readbyqxmd.com/read/28068902/bacterial-microbiota-of-kazakhstan-cheese-revealed-by-single-molecule-real-time-smrt-sequencing-and-its-comparison-with-belgian-kalmykian-and-italian-artisanal-cheeses
#7
Jing Li, Yi Zheng, Haiyan Xu, Xiaoxia Xi, Qiangchuan Hou, Shuzhen Feng, Laga Wuri, Yanfei Bian, Zhongjie Yu, Lai-Yu Kwok, Zhihong Sun, Tiansong Sun
BACKGROUND: In Kazakhstan, traditional artisanal cheeses have a long history and are widely consumed. The unique characteristics of local artisanal cheeses are almost completely preserved. However, their microbial communities have rarely been reported. The current study firstly generated the Single Molecule, Real-Time (SMRT) sequencing bacterial diversity profiles of 6 traditional artisanal cheese samples of Kazakhstan origin, followed by comparatively analyzed the microbiota composition between the current dataset and those from cheeses originated from Belgium, Russian Republic of Kalmykia (Kalmykia) and Italy...
January 9, 2017: BMC Microbiology
https://www.readbyqxmd.com/read/28068269/chitosan-incorporated-in-a-total-etch-adhesive-system-antimicrobial-activity-against-streptococcus-mutans-and-lactobacillus-casei
#8
Marcelo Figueiredo Lobato, Cecilia Pedroso Turssi, Flávia Lucisano Botelho do Amaral, Fabiana Mantovani Gomes França, Roberta Tarkany Basting
The aim of this study was to investigate the antimicrobial effect of an experimental adhesive system containing chitosan (0.2% and 0.5%) against Streptococcus mutans and Lactobacillus casei. Twenty-four extracted human third molars were used, and 4 cavities were prepared in each tooth. The teeth were contaminated with either S mutans (n = 12 teeth, 48 cavities) or L casei (n = 12 teeth, 48 cavities) microorganisms. One cavity in each tooth received 1 of the following treatments: negative control (no treatment [NC]), positive control (Adper Single Bond 2 [SB]), an experimental adhesive containing chitosan 0...
January 2017: General Dentistry
https://www.readbyqxmd.com/read/28067833/contribution-of-the-rgfd-quorum-sensing-peptide-to-rgf-regulation-and-host-cell-association-in-group-b-streptococcus
#9
Robert E Parker, David Knupp, Rim Al Safadi, Agnѐs Rosenau, Shannon D Manning
Streptococcus agalactiae (group B Streptococcus; GBS) is a common inhabitant of the genitourinary and/or gastrointestinal tract in up to 40% of healthy adults; however, this opportunistic pathogen is able to breach restrictive host barriers to cause disease and persist in harsh and changing conditions. This study sought to identify a role for quorum sensing, a form of cell to cell communication, in the regulation of the fibrinogen-binding (rgfBDAC) two-component system and the ability to associate with decidualized endometrial cells in vitro...
January 6, 2017: Genes
https://www.readbyqxmd.com/read/28067813/pneumococcal-colonization-in-the-familial-context-and-implications-for-anti-pneumococcal-immunization-in-adults-results-from-the-binocolo-project-in-sicily
#10
Fabio Tramuto, Emanuele Amodio, Giuseppe Calamusa, Vincenzo Restivo, Claudio Costantino, Francesco Vitale, On Behalf Of The Binocolo Group
The spread of Streptococcus pneumoniae within families has been scarcely investigated so far. This feasibility study aimed to estimate the prevalence of pneumococcal carriage in school-aged children and co-habiting relatives and to explore the potential link between the family environment and the sharing of pneumococcal serotypes covered by the vaccine. Oropharyngeal samples of 146 subjects belonging to 36 different family groups were molecularly tested for pneumococcal detection and serotyping. The overall prevalence of pneumococcal carriage was 65...
January 6, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28065676/rhamnolipids-from-non-pathogenic-burkholderia-thailandensis-e264-physicochemical-characterization-antimicrobial-and-antibiofilm-efficacy-against-oral-hygiene-related-pathogens
#11
Mohamed Elshikh, Scott Funston, Alif Chebbi, Syed Ahmed, Roger Marchant, Ibrahim M Banat
Biosurfactants are naturally occurring surface active compounds that have mainly been exploited for environmental applications and consumer products, with their biomedical efficacy an emerging area of research. Rhamnolipids area major group of biosurfactants that have been reported for their antimicrobial and antibiofilm efficacy. One of the main limiting factors for scaled up production and downstream applications of rhamnolipids is the fact that they are predominantly produced from the opportunistic pathogen Pseudomonas aeruginosa...
January 5, 2017: New Biotechnology
https://www.readbyqxmd.com/read/28063545/pr%C3%A3-vention-de-l-infection-n%C3%A3-onatale-%C3%A3-streptocoques-du-groupe-b-d-apparition-pr%C3%A3-coce
#12
Deborah Money, Victoria M Allen
OBJECTIF: Analyser les données issues de la littérature et formuler des recommandations sur la prise en charge des parturientes en vue de prévenir l'infection néonatale à streptocoques du groupe B d'apparition précoce. Parmi les révisions clés que renferme la présente directive clinique mise à jour, on trouve des modifications quant aux recommandations en ce qui concerne les schémas posologiques d'antibioprophylaxie, les épreuves de sensibilité et la prise en charge des femmes présentant une rupture prématurée des membranes...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063544/the-prevention-of-early-onset-neonatal-group-b-streptococcal-disease
#13
Deborah Money, Victoria M Allen
OBJECTIVE: To review the evidence in the literature and to provide recommendations on the management of pregnant women in labour for the prevention of early-onset neonatal group B streptococcal disease. The key revisions in this updated guideline include changed recommendations for regimens for antibiotic prophylaxis, susceptibility testing, and management of women with pre-labour rupture of membranes. OUTCOMES: Maternal outcomes evaluated included exposure to antibiotics in pregnancy and labour and complications related to antibiotic use...
December 2016: Journal of Obstetrics and Gynaecology Canada: JOGC, Journal D'obstétrique et Gynécologie du Canada: JOGC
https://www.readbyqxmd.com/read/28063458/thigh-pyomyositis-caused-by-group-a-streptococcus-in-an-immunocompetent-adult-without-any-cause
#14
Kensuke Minami, Tsuneaki Kenzaka, Ayako Kumabe, Masami Matsumura
BACKGROUND: Pyomyositis is typically caused by Staphylococcus aureus, and is rare in temperate climates, although its prevalence has been recently increasing. This infection often involves the thigh, and is associated with immunodeficiency. CASE PRESENTATION: We report the case of a healthy 20-year-old Japanese woman who experienced a fever and continuous pain for several days. She was admitted to our hospital and was diagnosed with pyomyositis after we discovered an abscess between the muscles of her dorsal distal left thigh using computed tomography...
January 7, 2017: BMC Research Notes
https://www.readbyqxmd.com/read/28062316/discovery-of-streptococcus-pneumoniae-serogroup-35-variants-in-australian-patients
#15
Megan Staples, Rikki M A Graham, Vicki Hicks, Janet Strachan, Anders Gonçalves da Silva, Jade Peverall, Veyatie Wicks, Amy V Jennison
OBJECTIVES: S. pneumoniae isolates from Australian invasive pneumococcal disease cases displaying an atypical 35B phenotype. Whole genome sequencing was used to analyse these strains and identify changes to the capsule gene regions. METHODS: Four atypical serogroup 35 isolates from Australian reference laboratories were unable to be assigned to one of the four known group 35 serotypes by the Quellung serotyping method. Genetic characterisation of the capsule locus was performed by bioinformatic analysis of whole genome sequencing data for all isolates RESULTS: Genetic analysis identified four independent disruptions to the wciG gene, which encodes an O-acetyltransferase responsible for the O-acetylation of the 6Galβ1 residue in the capsular polysaccharide repeat unit of serotype 35B...
January 3, 2017: Clinical Microbiology and Infection
https://www.readbyqxmd.com/read/28061775/immunization-with-streptococcus-suis-bacterin-plus-recombinant-sao-protein-in-sows-conveys-passive-immunity-to-their-piglets
#16
Kai-Jen Hsueh, Li-Ting Cheng, Jai-Wei Lee, Yao-Chi Chung, Wen-Bin Chung, Chun-Yen Chu
BACKGROUND: Streptococcus suis (S. suis) causes arthritis, meningitis, septicemia, and sudden death in pigs and is also an zoonotic agent for humans. The present study demonstrated that immunization with recombinant Sao-L (surface antigen one-L, rSao-L) protein from a strain of S. suis serotype 2 in pigs was able to increase cross-serotype protection against S. suis serotype 1 and 2 challenge. Since weaning piglets are more susceptible to S. suis infections due to the stresses associated with weaning, prepartum immunization in sows may convey passive immunity to piglets and provide protection...
January 7, 2017: BMC Veterinary Research
https://www.readbyqxmd.com/read/28060047/genotype-characterization-of-group-b-streptococcus-isolated-from-infants-with-invasive-diseases-in-south-korea
#17
Hyun Mi Kang, Hoan Jong Lee, Hyunju Lee, Dae Sun Jo, Hye Soo Lee, Taek Soo Kim, Jeong Hwan Shin, Ki Wook Yun, Bongjin Lee, Eun Hwa Choi
BACKGROUND: Group B Streptococcus (GBS) is one of the leading causes of invasive infections in infants. This study aimed to investigate the genotypic diversity of GBS causing invasive infections in infants and to observe the prevalence of the highly virulent clone in South Korea. METHODS: Invasive strains of GBS were collected prospectively from infants admitted at four hospitals during 1995 to 2015. Serotype and multilocus sequence typing was determined. All isolates underwent PCR amplification to detect the presence of the hypervirulent surface adhesin (hvgA) gene...
January 3, 2017: Pediatric Infectious Disease Journal
https://www.readbyqxmd.com/read/28059611/molecular-characterization-of-pneumococcal-surface-protein-k-a-potential-pneumococcal-vaccine-antigen
#18
A-Yeung Jang, Ho Seong Seo, Shunmei Lim, Gook-Hyun Chung, Han Wool Kim, Sangyong Lim, Lei Zhao, In-Ho Park, Jae Hyang Lim, Kyung-Hyo Kim
The pneumococcal capsule is indispensable for pathogenesis in systemic infections; however, many pneumococcal diseases, including conjunctivitis, otitis media, and some systemic infections in immunocompromised patients, are caused by nonencapsulated Streptococcus pneumoniae (NESp). Null capsule clade 1 (NCC1), found in group 2 NESp, expresses pneumococcal surface protein K (PspK) and is becoming prevalent among pneumococcal organisms owing to the widespread use of pneumococcal conjugate vaccines. Despite its clinical importance, the molecular mechanisms underlying the prevalence of NCC1 have not been fully elucidated...
January 6, 2017: Virulence
https://www.readbyqxmd.com/read/28057653/hospitalisation-with-community-acquired-pneumonia-among-patients-with-type-2-diabetes-an-observational-population-based-study-in-spain-from-2004-to-2013
#19
Ana López-de-Andrés, Javier de Miguel-Díez, Isabel Jiménez-Trujillo, Valentín Hernández-Barrera, José M de Miguel-Yanes, Manuel Méndez-Bailón, Napoleón Pérez-Farinós, Miguel Á Ngel Salinero-Fort, Rodrigo Jiménez-García
OBJECTIVES: To describe trends in the incidence and outcomes of community-acquired pneumonia (CAP) hospitalisations among patients with or without diabetes in Spain (2004-2013). DESIGN: Retrospective, observational study using the Spanish National Hospital Discharge Database (Conjunto Mínimo Básico de Datos (CMBD)). SETTING: Spain. PARTICIPANTS: We used national hospital discharge data to select all hospital admissions for CAP...
January 5, 2017: BMJ Open
https://www.readbyqxmd.com/read/28055130/effect-of-biochanin-a-on-corn-grain-zea-mays-fermentation-by-bovine-rumen-amylolytic-bacteria
#20
Brittany E Harlow, Michael D Flythe, Glen E Aiken
AIMS: The objective was to determine the effect of biochanin A (BCA), an isoflavone produced by red clover (Trifolium pratense L.), on corn fermentation by rumen microorganisms. METHODS AND RESULTS: When bovine rumen bacterial cell suspensions (n = 3) were incubated (24 h, 39 °C) with ground corn, amylolytic bacteria including group D Gram-positive cocci (GPC; Streptococcus bovis; enterococci) proliferated, cellulolytic bacteria were inhibited, lactate accumulated, and pH declined...
January 5, 2017: Journal of Applied Microbiology
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