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https://www.readbyqxmd.com/read/28521306/visible-light-sensitive-titanium-dioxide-nanoplatform-for-tumor-responsive-fe2-liberating-and-artemisinin-delivery
#1
Huijuan Zhang, Hongling Zhang, Xing Zhu, Xiaoge Zhang, Qianqian Chen, Jianjiao Chen, Lin Hou, Zhenzhong Zhang
Artemisinin is a kind of Fe2+-dependent drugs. Artemisinin and Fe2+ co-transport systems can improve its anti-tumor effect. In this study, a visible light-sensitive nanoplatform (HA-TiO2-IONPs/ART) was developed. Detailed investigation demonstrated that HA-TiO2-IONPs/ART could realize Fe2+ and artemisinin synchronous co-delivery and tumor-responsive release. This feature enhanced the anti-tumor efficiency of artemisinin significantly. In vitro results proved that hyaluronic acid modification could improve the biocompatibility, dispersion stability and cytophagy ability of nanocarriers...
May 5, 2017: Oncotarget
https://www.readbyqxmd.com/read/28510318/report-from-the-american-society-of-transplantation-conference-on-donor-heart-selection-in-adult-cardiac-transplantation-in-the-u-s
#2
J Kobashigawa, K Khush, M Colvin, M Acker, A Van Bakel, H Eisen, Y Naka, J Patel, D A Baran, T Daun, M Luu, M Olymbios, J Rogers, V Jeevanandam, F Esmailian, F D Pagani, B Lima, J Stehlik
Cardiac transplantation remains the only definitive treatment for end-stage heart failure. Transplantation rates are limited by a shortage of donor hearts. This shortage is magnified because many hearts are discarded due to strict selection criteria and concern for regulatory reprimand for less than optimal post-transplant outcomes. There is no standardized approach to donor selection despite proposals to liberalize acceptance criteria. A donor heart selection conference was organized to facilitate discussion, and generate ideas for future research...
May 16, 2017: American Journal of Transplantation
https://www.readbyqxmd.com/read/28493914/take-me-where-i-want-to-go-institutional-prestige-advisor-sponsorship-and-academic-career-placement-preferences
#3
Diogo L Pinheiro, Julia Melkers, Sunni Newton
Placement in prestigious research institutions for STEM (science, technology, engineering, and mathematics) PhD recipients is generally considered to be optimal. Yet some doctoral recipients are not interested in intensive research careers and instead seek alternative careers, outside but also within academe (for example teaching positions in Liberal Arts Schools). Recent attention to non-academic pathways has expanded our understanding of alternative PhD careers. However, career preferences and placements are also nuanced along the academic pathway...
2017: PloS One
https://www.readbyqxmd.com/read/28463732/changes-in-nursing-students-perceptions-of-research-and-evidence-based-practice-after-completing-a-research-course
#4
Carrie N Keib, Stephanie M Cailor, Mary E Kiersma, Aleda M H Chen
BACKGROUND: Nurses need a sound education in research and evidence-based practice (EBP) to provide patients with optimal care, but current teaching methods could be more effective. OBJECTIVES: To evaluate the changes in nursing students 1) perceptions of research and EBP, 2) confidence in research and EBP, and 3) interest in research participation after completing a course in research and EBP. DESIGN: A pre-post assessment design was utilized to compare changes in students...
April 18, 2017: Nurse Education Today
https://www.readbyqxmd.com/read/28447028/flipping-classrooms-in-a-school-of-public-health
#5
Steven W Howard, Darcell P Scharff, Travis M Loux
Alternative course formats are gaining increasing attention in higher education. The literature provides a number of examples and studies of flipped classrooms in the medical sciences and liberal arts and sciences. However, fewer than five papers on flipped classes in graduate public health courses have been published, and none in health management. Because graduate public health education is competency based, it seems that a flipped approach with its applied nature would be an appropriate form of teaching public health courses...
2017: Frontiers in Public Health
https://www.readbyqxmd.com/read/28363387/promoting-the-future-of-nursing-by-increasing-zest-for-research-in-undergraduate-nursing-students
#6
Adejoke B Ayoola, Yenupini J Adams, Kendra J Kamp, Gail L Zandee, Cheryl Feenstra, Mary M Doornbos
Nurses are expected to deliver cost-effective, high-quality care. In order to provide this care, nurse researchers are needed to evaluate and research effective health care models and interventions. By including research concepts within a baccalaureate nursing program, interest in nursing research can be increased. The purpose of this article is to present a case study of strategies used in an undergraduate liberal arts nursing program to promote zest in research and increase the pursuit of graduate studies among baccalaureate nursing students...
March 2017: Journal of Professional Nursing: Official Journal of the American Association of Colleges of Nursing
https://www.readbyqxmd.com/read/28328252/liberal-entity-extraction-rapid-construction-of-fine-grained-entity-typing-systems
#7
Lifu Huang, Jonathan May, Xiaoman Pan, Heng Ji, Xiang Ren, Jiawei Han, Lin Zhao, James A Hendler
The ability of automatically recognizing and typing entities in natural language without prior knowledge (e.g., predefined entity types) is a major challenge in processing such data. Most existing entity typing systems are limited to certain domains, genres, and languages. In this article, we propose a novel unsupervised entity-typing framework by combining symbolic and distributional semantics. We start from learning three types of representations for each entity mention: general semantic representation, specific context representation, and knowledge representation based on knowledge bases...
March 2017: Big Data
https://www.readbyqxmd.com/read/28315810/trappings-of-femininity-a-test-of-the-beauty-as-currency-hypothesis-in-shaping-college-women-s-gender-activism
#8
Rachel M Calogero, Tracy L Tylka, Lois C Donnelly, Amber McGetrick, Andrea Medrano Leger
This study investigated whether believing beauty is a primary currency for women operates as an antecedent force in the relation between self-objectification and gender activism. Ninety-four ethnically diverse women attending a small liberal arts college in the southeastern United States completed the study questionnaires online for course credit. Preliminary results demonstrated beauty as currency belief, self-objectification, and support for the gender status quo were negatively associated with gender activism...
March 17, 2017: Body Image
https://www.readbyqxmd.com/read/28295183/rank-based-permutation-approaches-for-non-parametric-factorial-designs
#9
Maria Umlauft, Frank Konietschke, Markus Pauly
Inference methods for null hypotheses formulated in terms of distribution functions in general non-parametric factorial designs are studied. The methods can be applied to continuous, ordinal or even ordered categorical data in a unified way, and are based only on ranks. In this set-up Wald-type statistics and ANOVA-type statistics are the current state of the art. The first method is asymptotically exact but a rather liberal statistical testing procedure for small to moderate sample size, while the latter is only an approximation which does not possess the correct asymptotic α level under the null...
March 15, 2017: British Journal of Mathematical and Statistical Psychology
https://www.readbyqxmd.com/read/28255600/impact-of-participation-in-community-based-research-among-undergraduate-and-graduate-students
#10
Cheryl L George, Jennifer Wood-Kanupka, Kathryn N Oriel
Participation in community-based research provides college students with a high-impact experience involving both research and service learning. Presently, the impact of participation in community-based research projects has been measured most often through the use of post-learning course evaluations and case studies. The authors describe the impact of participation in community-based research, at a small liberal arts college, on undergraduate education students and graduate physical therapy students using the Community-Based Research Student Learning Outcomes Survey...
2017: Journal of Allied Health
https://www.readbyqxmd.com/read/28236053/almost-psychiatry-the-impact-of-teaching-child-and-adolescent-mental-health-studies-to-undergraduate-college-students
#11
Ursula Diamond, Christina A Di Bartolo, Emily Badin, Jess P Shatkin
OBJECTIVE: The Child and Adolescent Mental Health Studies (CAMS) program is housed in a Liberal Arts undergraduate college of a large research university. Psychiatrists, clinical psychologists, and social workers at the university's medical center teach the courses. The purpose of this study is to evaluate the extent to which CAMS encourages graduates of the program to pursue a career in child and adolescent mental health (CAMH). METHODS: In 2015-2016, graduates of the CAMS program were invited to participate in a mixed methods study...
February 24, 2017: Academic Psychiatry
https://www.readbyqxmd.com/read/28151096/development-of-attitudes-toward-homosexuality-scale-for-indians-ahsi
#12
Kanika K Ahuja
Attitudes toward homosexuality vary across cultures, with the legal and societal position being rather complicated in India. This study describes the process of developing and validating a Likert-type scale to assess attitudes toward homosexuality among heterosexuals. Phase 1 describes the development of the scale. Items were written based on thematic analysis of narratives generated from 50 college students and reviewing existing scales. After administering the 70-item scale to 68 participants, item analysis yielded 20 statements with item-total correlations over ...
February 2, 2017: Journal of Homosexuality
https://www.readbyqxmd.com/read/28145270/the-flipped-classroom-allows-for-more-class-time-devoted-to-critical-thinking
#13
Lara R DeRuisseau
The flipped classroom was utilized in a two-semester, high-content science course that enrolled between 50 and 80 students at a small liberal arts college. With the flipped model, students watched ~20-min lectures 2 days/wk outside of class. These videos were recorded via screen capture and included a detailed note outline, PowerPoint slides, and review questions. The traditional format included the same materials, except that lectures were delivered in class each week and spanned the entire period. During the flipped course, the instructor reviewed common misconceptions and asked questions requiring higher-order thinking, and five graded case studies were performed each semester...
December 1, 2016: Advances in Physiology Education
https://www.readbyqxmd.com/read/28028190/beliefs-and-attitudes-associated-with-hookah-smoking-among-a-united-states-college-population
#14
Mary P Martinasek, Linda G Haddad, Christopher W Wheldon, Tracey E Barnett
BACKGROUND: This study explores the differences among smokers of waterpipe tobacco in a college population to better inform campaigns to curb waterpipe use. METHODS: Participants included undergraduate and graduate students attending a liberal arts university in Florida. E-mail-based, cross-sectional surveys were collected in 2 sequential years. RESULTS: The majority of respondents (64%) reported having ever smoked a hookah, even if just 1-2 puffs...
December 27, 2016: Respiratory Care
https://www.readbyqxmd.com/read/27977287/strengths-and-weaknesses-of-the-young-black-men-masculinities-and-mental-health-ybmen-facebook-project
#15
Daphne C Watkins, Julie Ober Allen, Janelle R Goodwill, Blake Noel
The Young Black Men, Masculinities, and Mental Health (YBMen) project is a Facebook-based intervention that provides mental health education and social support to young Black men. The YBMen project was created to better understand and address the pressures and needs of young Black men, particularly with regard to issues related to their conceptualization of masculinity and mental health. Black men from a 2-year liberal arts college in the Midwest (United States) enrolled in the YBMen pilot project. The purpose of this study is to report what participants in the YBMen pilot project liked and disliked about the intervention, along with their suggestions for improvement...
December 15, 2016: American Journal of Orthopsychiatry
https://www.readbyqxmd.com/read/27925099/care-of-the-self-and-power-relations-female-nurses-taking-care-of-other-women
#16
Ana Renata Moura Rabelo, Kênia Lara Silva
Objective: to analyze the care of self of female nurses and the power relations established by them in the care of other women. Method: integrative review of literature published between 2005 and 2015. There were 25 publications in the sample. Results: qualitative state of the art with reference domain of a liberating perspective, based on humanization, autonomy and empowerment as a risk reduction strategy in the practice of care to women...
November 2016: Revista Brasileira de Enfermagem
https://www.readbyqxmd.com/read/27919371/a-machine-learning-based-framework-to-identify-type-2-diabetes-through-electronic-health-records
#17
Tao Zheng, Wei Xie, Liling Xu, Xiaoying He, Ya Zhang, Mingrong You, Gong Yang, You Chen
OBJECTIVE: To discover diverse genotype-phenotype associations affiliated with Type 2 Diabetes Mellitus (T2DM) via genome-wide association study (GWAS) and phenome-wide association study (PheWAS), more cases (T2DM subjects) and controls (subjects without T2DM) are required to be identified (e.g., via Electronic Health Records (EHR)). However, existing expert based identification algorithms often suffer in a low recall rate and could miss a large number of valuable samples under conservative filtering standards...
January 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/27856548/the-pulse-vision-change-rubrics-version-1-0-a-valid-and-equitable-tool-to-measure-transformation-of-life-sciences-departments-at-all-institution-types
#18
Loretta Brancaccio-Taras, Pamela Pape-Lindstrom, Marcy Peteroy-Kelly, Karen Aguirre, Judy Awong-Taylor, Teri Balser, Michael J Cahill, Regina F Frey, Thomas Jack, Michael Kelrick, Kate Marley, Kathryn G Miller, Marcy Osgood, Sandra Romano, J Akif Uzman, Jiuqing Zhao
The PULSE Vision & Change Rubrics, version 1.0, assess life sciences departments' progress toward implementation of the principles of the Vision and Change report. This paper reports on the development of the rubrics, their validation, and their reliability in measuring departmental change aligned with the Vision and Change recommendations. The rubrics assess 66 different criteria across five areas: Curriculum Alignment, Assessment, Faculty Practice/Faculty Support, Infrastructure, and Climate for Change. The results from this work demonstrate the rubrics can be used to evaluate departmental transformation equitably across institution types and represent baseline data about the adoption of the Vision and Change recommendations by life sciences programs across the United States...
2016: CBE Life Sciences Education
https://www.readbyqxmd.com/read/27819047/nonradiating-and-radiating-modes-excited-by-quantum-emitters-in-open-epsilon-near-zero-cavities
#19
Iñigo Liberal, Nader Engheta
Controlling the emission and interaction properties of quantum emitters (QEs) embedded within an optical cavity is a key technique in engineering light-matter interactions at the nanoscale, as well as in the development of quantum information processing. State-of-the-art optical cavities are based on high quality factor photonic crystals and dielectric resonators. However, wealthier responses might be attainable with cavities carved in more exotic materials. We theoretically investigate the emission and interaction properties of QEs embedded in open epsilon-near-zero (ENZ) cavities...
October 2016: Science Advances
https://www.readbyqxmd.com/read/27810867/alternative-realities-faculty-and-student-perceptions-of-instructional-practices-in-laboratory-courses
#20
Christopher W Beck, Lawrence S Blumer
Curricular reform efforts depend on our ability to determine how courses are taught and how instructional practices affect student outcomes. In this study, we developed a 30-question survey on inquiry-based learning and assessment in undergraduate laboratory courses that was administered to 878 students in 54 courses (41 introductory level and 13 upper level) from 20 institutions (four community colleges, 11 liberal arts colleges, and five universities, of which four were minority-serving institutions). On the basis of an exploratory factor analysis, we defined five constructs: metacognition, feedback and assessment, scientific synthesis, science process skills, and instructor-directed teaching...
2016: CBE Life Sciences Education
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