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https://www.readbyqxmd.com/read/28214498/vasculitic-and-autoimmune-wounds
#1
REVIEW
Victoria K Shanmugam, Divya Angra, Hamza Rahimi, Sean McNish
OBJECTIVE: Chronic wounds are a major cause of morbidity and mortality. Approximately 20% to 23% of nonhealing wounds that are refractory to vascular intervention have other causes, including vasculitis, pyoderma gangrenosum, and other autoimmune diseases. The purpose of this article was to review the literature across medical and surgical specialties with regard to refractory chronic wounds associated with vasculitis and autoimmune diseases and to delineate clinical outcomes of these wounds in response to vascular and other interventions...
March 2017: Journal of Vascular Surgery. Venous and Lymphatic Disorders
https://www.readbyqxmd.com/read/28210817/-compression-therapy-of-chronic-leg-ulcers-practical-aspects
#2
J Dissemond, K Protz, J Hug, S Reich-Schupke, K Kröger
Compression therapy, together with modern moist wound treatment, is the basis for a successful conservative treatment of patients with chronic leg ulcers. In clinical practice, it is often the patients themselves who apply compression therapies. Many of the mostly elderly patients, however, are not able to reach their legs and feet due to movement restrictions, such as arthritis, arthrosis and even obesity. An adequate compression therapy also requires extensive experience and regular training. In practice only the minority of patients can perform bandaging well and therefore this should not be recommended...
February 16, 2017: Zeitschrift Für Gerontologie und Geriatrie
https://www.readbyqxmd.com/read/28207017/healing-of-leg-ulcers-associated-with-granulomatosis-with-polyangiitis-wegener-granulomatosis-after-rituximab-therapy
#3
Scott Kindle, Joseph Fanciullo
No abstract text is available yet for this article.
January 2017: Cutis; Cutaneous Medicine for the Practitioner
https://www.readbyqxmd.com/read/28203074/temperature-and-ph-sensitive-wearable-materials-for-monitoring-foot-ulcers
#4
Pietro Salvo, Nicola Calisi, Bernardo Melai, Valentina Dini, Clara Paoletti, Tommaso Lomonaco, Andrea Pucci, Fabio Di Francesco, Alberto Piaggesi, Marco Romanelli
Foot ulcers account for 15% of comorbidities associated with diabetes. Presently, no device allows the status of foot ulcers to be continuously monitored when patients are not hospitalized. In this study, we describe a temperature and a pH sensor capable of monitoring diabetic foot and venous leg ulcers developed in the frame of the seventh framework program European Union project SWAN-iCare (smart wearable and autonomous negative pressure device for wound monitoring and therapy). Temperature is measured by exploiting the variations in the electrical resistance of a nanocomposite consisting of multiwalled carbon nanotubes and poly(styrene-b-(ethylene-co-butylene)-b-styrene)...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28194803/the-current-spectrum-of-contact-sensitization-in-patients-with-chronic-leg-ulcers-or-stasis-dermatitis%C3%A2-%C3%A2-new-data-from-the-information-network-of-departments-of-dermatology-ivdk
#5
Cornelia Erfurt-Berge, Johannes Geier, Vera Mahler
BACKGROUND: Patients with lower leg dermatitis, chronic venous insufficiency or chronic leg ulcers have a high prevalence of contact sensitization. OBJECTIVES: To identify the current spectrum of contact allergens in these patients. PATIENTS AND METHODS: Data of the Information Network of Departments of Dermatology on 5264 patients with the above diagnoses from the years 2003 to 2014 (study group) were compared with data on 4881 corresponding patients from 1994 to 2003 (historical control group) and with a current control group without these diagnoses (n = 55 510)...
February 14, 2017: Contact Dermatitis
https://www.readbyqxmd.com/read/28191667/metastatic-recurrence-of-17-years-relapse-free-melanoma-during-anti-tnfa-therapy
#6
Ioana Cosgarea, Andreas Körber, Dorothee Dill, Dirk Schadendorf, Selma Ugurel
Tumor-necrosis-factor-alpha (TNFa) is an innate cytokine involved in regulating inflammation, immunity, tumorigenesis, and apoptosis. TNFa inhibitors became a powerful tool in the treatment of auto-immune inflammatory diseases such as Crohn's disease, ulcerative colitis, rheumatoid arthritis and psoriasis. Known side effects of TNFa inhibitors range from infections to malignancies [1]. We report a male patient who was in 1998 at age 36 diagnosed with amelanotic melanoma of the leg, Breslow thickness 11.0 mm, no ulceration...
February 13, 2017: Journal of the European Academy of Dermatology and Venereology: JEADV
https://www.readbyqxmd.com/read/28191659/lumbar-syndrome-a-case-manifesting-as-cutaneous-infantile-hemangiomas-of-the-lower-extremity-perineum-and-gluteal-region-and-a-review-of-published-work
#7
Xia Yu, Jia Zhang, Zhouwei Wu, Ming Liu, Ruhong Chen, Yan Gu, Ming Li, Zhirong Yao
We herein report a rare case of LUMBAR syndrome. A 1-month-old female infant presented with extensive segmental hemangiomas on the left lower extremity, left perineum and gluteal region with ulceration. Bilateral labia minoras were asymmetrical. Both legs were asymmetrical with left leg atrophy, and the intergluteal cleft was deviated. A dark red pustule and a sacrococcygeal dimple could be seen in the lumbosacral region. Lipomyelomeningocele, tethered cord and sacrum dysplasia were noted by magnetic resonance imaging...
February 13, 2017: Journal of Dermatology
https://www.readbyqxmd.com/read/28182533/the-reality-of-routine-practice-a-pooled-data-analysis-on-chronic-wounds-treated-with-tlc-nosf-wound-dressings
#8
K C Münter, S Meaume, M Augustin, P Senet, J C Kérihuel
OBJECTIVE: A number of randomised controlled trials (RCT) have compared control groups with TLC-NOSF dressings (UrgoStart) on chronic wounds. Our aim was to determine whether the clinical trials' results translate into routine management of such wounds, by pooling the data from real-life observational studies. METHOD: Observational studies, conducted in France and Germany, evaluating current practices in patients suffering from non-selected chronic wounds treated with a TLC-NOSF dressing were identified...
February 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28182532/healing-of-an-arterial-leg-ulcer-by-compression-bandaging-a-case-report
#9
C Sanchez, H Partsch
This case report demonstrates that arterial ulcers may heal with compression therapy. The patient was a 72-year-old woman with elevated blood pressure and type II diabetes mellitus, who underwent angiography because of a painful, non-healing ulcer over the shin. The angiography showed multisegment arterial occlusive disease, not amenable to surgical revascularisation. After 4 months of wearing inelastic bandages, with increased pressure over the ulcer area and hypertension and diabetes under control, the patient was pain-free and the ulcer had healed...
February 2017: Journal of Wound Care
https://www.readbyqxmd.com/read/28177542/reduced-prevalence-and-severity-of-wounds-following-implementation-of-the-champions-for-skin-integrity-model-to-facilitate-uptake-of-evidence-based-practice-in-aged-care
#10
Helen E Edwards, Anne M Chang, Michelle Gibb, Kathleen J Finlayson, Christina Parker, Maria O'Reilly, Jan McDowell, Patricia Shuter
AIMS: To evaluate the implementation of the Champions for Skin Integrity Model on facilitating uptake of evidence-based wound management and improving skin integrity in residents of aged care facilities BACKGROUND: The incidence of skin tears, pressure injuries and leg ulcers increases with age and such wounds can be a serious issue in aged care facilities. Older adults are not only at higher risk for wounds related to chronic disease, but also injuries related to falls and manual handling requirements...
February 8, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28172673/p203-factors-associated-with-restless-legs-syndrome-in-patients-with-ulcerative-colitis-a-study-in-a-tertiary-care-center-in-romania
#11
R C Popa, A Savin, I Ungureanu, O Gavrilescu, M Dranga, A M Chiosa, O Jigaranu, I Popa, C Mihai, C Cijevschi-Prelipcean
No abstract text is available yet for this article.
February 1, 2017: Journal of Crohn's & Colitis
https://www.readbyqxmd.com/read/28166662/-ischemic-origin-of-diabetic-foot-disease-epidemiology-difficulties-of-diagnosis-options-for-prevention-and-revascularization
#12
Endre Kolossváry, Zoltán Bánsághi, Gábor Viktor Szabó, Zoltán Járai, Katalin Farkas
"Diabetic foot" as definition covers a multifactorial clinical condition. According to the recent epidemiological data, the role of lower limb ischemia is getting more influential over other pathological causes, like neuropathy, infections and bone or soft tissue deformity. In diabetes, vascular disease leads to increased risk for leg ulcers and minor or major amputations. The traditional diagnostic tools for recognition of peripheral arterial disease have limited value because of diabetes specific clinical manifestations...
February 2017: Orvosi Hetilap
https://www.readbyqxmd.com/read/28163175/thrombosis-of-the-inferior-vena-cava-after-endovascular-aortic-repair-in-a-patient-with-may-thurner-syndrome-case-report-and-literature-review
#13
Firouza Dahi, Asimakis Gkremoutis, Marc Harth, Thomas Schmitz-Rixen, Michael Keese
Inferior vena cava (IVC) thrombosis is a rare complication of abdominal aortic aneurysm (AAA). A 70-year-old male patient of Italian origin presented with a 9.3 x 8.4 cm infrarenal AAA, which was treated by endovascular aortic repair (EVAR). He reported a history of ulcerative colitis and was on prednisolone 80 mg daily. Seven weeks postoperatively the patient was readmitted with a deep vein thrombosis including both iliac veins and IVC, and bilateral pulmonary embolism. Venous thrombectomy and decompression of the IVC was performed by partial resection of the aneurysm sac...
February 2, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28162862/maltodextrin-ascorbic-acid-stimulates-wound-closure-by-increasing-collagen-turnover-and-tgf-%C3%AE-1-expression-in%C3%A2-vitro-and-changing-the-stage-of-inflammation-from-chronic-to-acute-in%C3%A2-vivo
#14
Rosa M Salgado, Otilia Cruz-Castañeda, Francisco Elizondo-Vázquez, Lucia Pat, Anabel De la Garza, Saúl Cano-Colín, Leticia Baena-Ocampo, Edgar Krötzsch
It has been reported that carbohydrates confer physicochemical properties to the wound environment that improves tissue repair. We evaluated in vitro and in vivo wound healing during maltodextrin/ascorbic acid treatment. In a fibroblast monolayer scratch assay, we demonstrated that maltodextrin/ascorbic acid stimulated monolayer repair by increasing collagen turnover coordinately with TGF-β1 expression (rising TGF-β1 and MMP-1 expression, as well as gelatinase activity, while TIMP-1 was diminished), similar to in vivo trends...
February 1, 2017: Journal of Tissue Viability
https://www.readbyqxmd.com/read/28162373/-151-chronic-leg-ulcer-pain-a-need-for-effective-topical-analgesia
#15
S Parra, P Lacouture, H Giles
No abstract text is available yet for this article.
April 2016: Journal of Pain: Official Journal of the American Pain Society
https://www.readbyqxmd.com/read/28153676/a-model-to-estimate-cost-savings-in-diabetic-foot-ulcer-prevention-efforts
#16
Neal R Barshes, Samira Saedi, James Wrobel, Panos Kougias, O Erhun Kundakcioglu, David G Armstrong
BACKGROUND: Sustained efforts at preventing diabetic foot ulcers (DFUs) and subsequent leg amputations are sporadic in most health care systems despite the high costs associated with such complications. We sought to estimate effectiveness targets at which cost-savings (i.e. improved health outcomes at decreased total costs) might occur. METHODS: A Markov model with probabilistic sensitivity analyses was used to simulate the five-year survival, incidence of foot complications, and total health care costs in a hypothetical population of 100,000 people with diabetes...
January 21, 2017: Journal of Diabetes and its Complications
https://www.readbyqxmd.com/read/28139903/endovenous-laser-ablation-in-patients-with-severe-primary-chronic-venous-insufficiency
#17
Vladimir Starodubtsev, Mikhail Lukyanenko, Andrey Karpenko, Pavel Ignatenko
BACKGROUND: The aim of study was to estimate the safety and efficacy of using laser wavelength of 1560 nm with the foam sclerotherapy (FS) of varicose veins (VVs) for the treatment of severe primary chronic venous insufficiency (CVI, C4-C6) in patients with different diameters of the proximal segment (DPS) of the great saphenous vein (GSV). METHODS: We have separated the patients into two groups depending on the size of GSV: group 1 (281 cases; DPS of GSV less than 15 mm) and group 2 (210 cases; DPS of GSV more than 15 mm)...
January 31, 2017: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/28135201/use-of-a-dehydrated-amniotic-membrane-allograft-in-the-treatment-of-lower-extremity-wounds-a-retrospective-cohort-study
#18
Eric J Lullove
: Injuries to the skin are extensively costly to the health care system. When caused by metabolic and vascular compromise, these injuries are even more foreboding for patients. They can result in chronic inflammation, reduced mobility, and chronic pain. MATERIALS AND METHODS: Twenty patients were selected from the author's patient population at the West Boca Center for Wound Healing for a retrospective cohort study. Patients underwent a run-in period of 2 weeks, where standard of care was used to clear the wound of bioburden...
January 23, 2017: Wounds: a Compendium of Clinical Research and Practice
https://www.readbyqxmd.com/read/28128082/a-giant-basal-cell-carcinoma-misdiagnosed-and-mistreated-as-a-chronic-venous-ulcer
#19
Dijana Celić, Jasna Lipozenčić, Suzana Ljubojević Hadžavdić, Jolanda Kanižaj Rajković, Davorin Lončarić, Tajana Borlinić
Basal cell carcinoma (BCC) is the most common cutaneous malignancy. Giant BCCs are quite rare. They can cause extensive local invasion, disfigurement, and metastasis. We present a case of a 58-year-old woman with an unrecognized and inadequately treated ulcerated giant BCC sized 12.5 × 10.0 cm that occurred on her left lower leg without any sign of metastasis. Neglect and inadequate treatment of the primary lesion are the most important contributing factors responsible for size in giant BCC.
December 2016: Acta Dermatovenerologica Croatica: ADC
https://www.readbyqxmd.com/read/28116782/primary-cutaneous-diffuse-large-b-cell-lymphoma-presenting-as-chronic-non-healing-ulcer
#20
Victoria L Billero, Charlotte E LaSenna, Marco Romanelli, Alessio Giubellino, Robert A Brenes, Paolo Romanelli
Primary cutaneous diffuse large B-cell lymphoma is an uncommon and aggressive lymphoproliferative disorder with a rapid growth rate and dismal prognosis. We present the case of a 91-year-old female with an unusual manifestation of primary cutaneous diffuse large B-cell lymphoma, mimicking other more prevalent diseases like chronic non-healing venous ulceration. Dermatopathologic evaluation rendered the correct diagnosis. A discussion of this rare presentation is important for clinician consideration to prevent misdiagnosis and prolongation of proper management in patients with chronic non-healing leg ulcers...
January 24, 2017: International Wound Journal
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