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Vaccination debate

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https://www.readbyqxmd.com/read/29031651/vaccine-criticism-presence-and-arguments-on-french-speaking-websites
#1
A Nugier, F Limousi, N Lydié
OBJECTIVE: To evaluate the presence of vaccine criticism on the French Web and to analyze strategies and arguments used by opponents of vaccination. METHODS: The most frequently used keywords associated with the terms "vaccination" and "vaccine" on Google.fr in September 2013 were identified and searched for individually on Google.fr. The links presented in the first three pages of results were reviewed to identify the most frequent providers of information. The proportion of critical content was determined by website type and a content analysis was performed...
October 11, 2017: Médecine et Maladies Infectieuses
https://www.readbyqxmd.com/read/29028371/from-social-media-to-mainstream-news-the-information-flow-of-the-vaccine-autism-controversy-in-the-us-canada-and-the-uk
#2
S Mo Jang, Brooke W Mckeever, Robert Mckeever, Joon Kyoung Kim
Despite increasing warnings about inaccurate information online, little is known about how social media contribute to the widespread diffusion of unverified health information. This study addresses this issue by examining the vaccine-autism controversy. By looking into a large dataset of Twitter, Reddit posts, and online news over 20 months in the US, Canada, and the UK, our time-series analysis shows that Twitter drives news agendas, and Reddit follows news agendas regarding the vaccine-autism debate. Additionally, the results show that both Twitter and Reddit are more likely to discuss the vaccine-autism link compared to online news content...
October 13, 2017: Health Communication
https://www.readbyqxmd.com/read/29016491/expanding-prenatal-care-to-unauthorized-immigrant-women-and-the-effects-on-infant-health
#3
Jonas J Swartz, Jens Hainmueller, Duncan Lawrence, Maria I Rodriguez
OBJECTIVE: To measure the effect of access to prenatal care on unauthorized and low-income, new legal permanent resident immigrant women and their offspring. METHODS: We used a difference-in-differences design that leverages the staggered rollout of Emergency Medicaid Plus by county from 2008 to 2013 as a natural experiment to estimate the effect on health service utilization for women and health outcomes for their infants. Regular Medicaid pregnancies were used as an additional control in a triple difference design...
October 6, 2017: Obstetrics and Gynecology
https://www.readbyqxmd.com/read/28992986/pros-and-cons-of-vaccination-against-disease-caused-by-serogroup-b-meningococcal-disease
#4
REVIEW
Miguel Delgado Rodríguez, Ángela Domínguez García
A vaccine has recently been approved in the EU against meningococcal serogroup B, the main cause of meningococcal disease. There is a fierce debate about the decision regarding a universal vaccination in infants older than 2 months, as recommended by the majority of scientific societies. In western Europe the only country to have included the universal vaccination is the United Kingdom, with a lower incidence of the disease than Ireland. Other countries have also adopted it, such as the Czech Republic, Cuba and certain regions of Italy...
October 7, 2017: Medicina Clínica
https://www.readbyqxmd.com/read/28929711/-statistics-at-the-time-of-the-crisis
#5
Andrea Saltelli, Philip B Stark
Science lies nowadays in the centre of several storms. The better known is the finding of non-reproducibility of many scientific results, which stretches from the medical field (clinic and pre-clinic tests) to study on behaviour (priming research). Although the bad use of statistics is reported to be a patent cause of the reproducibility crisis, its deep reasons are to be sought elsewhere; particularly, in the passage from a regimen of little science - regulated by small communities of researchers - to the current big science - identified by a hypertrophic production of millions of research papers and by the imperative "publish or perish", in a setting dominated by market...
May 2017: Epidemiologia e Prevenzione
https://www.readbyqxmd.com/read/28928077/influenza-vaccine-use-to-protect-healthy-children-a-debated-topic
#6
Nicola Principi, Susanna Esposito
At the beginning of this century, a number of studies suggested that in healthy children, particularly those <2years of age, influenza could have a serious and complicated course, as it frequently led to hospitalization and sometimes, albeit rarely, to death. Moreover, pre-schoolers and school-age children were found to be among the most important causes of influenza transmission to the community, as they shed the virus for a longer time than adults and had frequent contact with greater numbers of individuals through day-care and school...
September 16, 2017: Vaccine
https://www.readbyqxmd.com/read/28926023/the-political-economy-of-bovine-tuberculosis-in-great-britain
#7
R M Bennett
A brief history of bovine tuberculosis (bTB) and its control in Great Britain (GB) is presented. Numerous diverse policies to control the disease in humans, cattle and wildlife have been pursued over the last 100 years and many millions of pounds have been spent. After notable success in reducing the incidence and prevalence of bTB in cattle in GB from the 1950s to the mid-1980s, the geographical spread of the disease and the number of cattle slaughtered have increased continually since that time, with a high point of bTB incidence in 2008...
April 2017: Revue Scientifique et Technique
https://www.readbyqxmd.com/read/28882443/debate-on-vaccines-and-autoimmunity-do-not-attack-the-author-yet-discuss-it-methodologically
#8
Nicola Luigi Bragazzi, Abdulla Watad, Howard Amital, Yehuda Shoenfeld
Since Jenner, vaccines and vaccinations have stirred a hot, highly polarized debate, leading to contrasting positions and feelings, ranging from acritical enthusiasm to blind denial. On the one hand, we find anti-vaccination movements which divulge and disseminate misleading information, myths, prejudices, and even frauds, with the main aim of denying that vaccination practices represent a major public health measure, being effective in controlling infectious diseases and safeguarding the wellbeing of entire communities...
September 4, 2017: Vaccine
https://www.readbyqxmd.com/read/28842185/early-diagnosis-of-pi3k%C3%AE-syndrome-in-a-2-years-old-girl-with-recurrent-otitis-and-enlarged-spleen
#9
F Saettini, M A Pelagatti, D Sala, D Moratto, S Giliani, R Badolato, A Biondi
Heterozygous gain of function mutations in the gene encoding p110δ subunit of PI3K have been recently associated with activated PI3K-δ syndrome (APDS), a novel combined immune deficiency characterized by recurrent sinopulmonary infections, lymphopenia, reduced class-switched memory B cells, lymphadenopathy, CMV and/or EBV viremia and EBV-related lymphoma. Here we report a dominant gain of function PIK3CD mutation (E1021K) in a patient presenting with recurrent otitis media, massive splenomegaly, and persistent EBV-viraemia...
August 31, 2017: Immunology Letters
https://www.readbyqxmd.com/read/28750852/assessment-of-biosecurity-and-control-measures-to-prevent-incursion-and-to-limit-spread-of-emerging-transboundary-animal-diseases-in-europe-an-expert-survey
#10
Anaïs Léger, Marco De Nardi, Robin Simons, Amie Adkin, Giuseppe Ru, Agustín Estrada-Peña, Katharina D C Stärk
Decision-makers and risk managers are often called upon to prioritise on and recommend suitable measures to prevent the risk of introduction and spread of pathogens. The main objective of this study was to assess the perceptions of experts in Italy, Switzerland and the United Kingdom concerning the importance, effectiveness, feasibility, costs and acceptability of selected biosecurity measures to prevent the introduction and limit the spread of rabies, blue tongue (BT) and classical swine fever (CSF). After identifying the most relevant measures by the project team, an expert knowledge elicitation was implemented through a questionnaire...
July 24, 2017: Vaccine
https://www.readbyqxmd.com/read/28738137/public-health-and-economic-consequences-of-vaccine-hesitancy-for-measles-in-the-united-states
#11
Nathan C Lo, Peter J Hotez
Importance: Routine childhood vaccination is declining in some regions of the United States due to vaccine hesitancy, which risks the resurgence of many infectious diseases with public health and economic consequences. There are ongoing policy debates on the state and national level, including legislation around nonmedical (personal-belief) exemptions for childhood vaccination and possibly a special government commission on vaccine safety, which may affect vaccine coverage. Objective: To estimate the number of measles cases in US children and the associated economic costs under scenarios of different levels of vaccine hesitancy, using the case example of measles, mumps, and rubella (MMR) vaccination and measles...
September 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28686042/the-hepatitis-e-virus-nonstructural-polyprotein
#12
Mohammad Khalid Parvez
Hepatitis E virus (HEV) is a globally important pathogen of acute and chronic hepatitis in humans. The HEV ORF1 gene encodes a nonstructural polyprotein, essential for RNA replication and virus infectivity. Expression and processing of ORF1 polyprotein are shown in prokaryotic and eukaryotic systems, however, its proteolysis into individual proteins is still debated. While molecular or biochemical characterization of methyltransferase, protease, hypervariable region, helicase and RNA polymerase domains in ORF1 has been achieved, the role of the X and Y domains in the HEV life cycle has only been demonstrated very recently...
August 2017: Future Microbiology
https://www.readbyqxmd.com/read/28649869/hivr4p-2016-partnering-for-prevention-conference-summary-and-highlights
#13
Barbara L Shacklett, Cynthia A Derdeyn, Morenike Oluwatoyin Folayan, Raphael J Landovitz, Colin Anthony, Anna-Janina Behrens, Thomas J Hope, Elise Landais, Lorna Leal, Jeanne M Marrazzo, Lynn Morris, Nelly Mugo, Kenneth Ngure, Veronica Noseda, Srinika Ranasinghe, Damien C Tully, Yegor Voronin, Mitchell Warren, Constantinos Kurt Wibmer, Irene Y Xie, Gabriella Scarlatti, Bargavi Thyagarajan
HIV Research for Prevention: AIDS Vaccine, Microbicide, and ARV-based Prevention Science (HIVR4P) was built on a growing consensus that effective HIV prevention requires a combination of approaches and that understanding, analyzing, and debating the cross-cutting issues that impact prevention research are all essential to combat the global HIV/AIDS epidemic. To that end, the biennial HIVR4P conference is dedicated to all biomedical HIV prevention research approaches, including HIV vaccines, microbicides, pre-exposure prophylaxis, and treatment as prevention...
August 2017: AIDS Research and Human Retroviruses
https://www.readbyqxmd.com/read/28634886/subcortical-brain-atrophy-in-gulf-war-illness
#14
Peka Christova, Lisa M James, Brian E Engdahl, Scott M Lewis, Adam F Carpenter, Apostolos P Georgopoulos
Gulf War Illness (GWI) is a multisystem disorder that has affected a substantial number of veterans who served in the 1990-1991 Gulf War. The brain is prominently affected, as manifested by the presence of neurological, cognitive and mood symptoms. Although brain dysfunction in GWI has been well documented (EBioMedicine 12:127-32, 2016), abnormalities in brain structure have been debated. Here we report a substantial (~10%) subcortical brain atrophy in GWI comprising mainly the brainstem, cerebellum and thalamus, and, to a lesser extent, basal ganglia, amygdala and diencephalon...
June 20, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28623027/ade-and-dengue-vaccination
#15
Ruth Aralí Martínez-Vega, Gabriel Carrasquila, Expedito Luna, José Ramos-Castañeda
The vaccine against Dengue virus (DENV), Dengvaxia® (CYD), produced by Sanofi-Pasteur, has been registered by several national regulatory agencies; nevertheless, the performance and security of this vaccine have been challenged in a series of recent papers. In this work, we intend to contribute to the debate by analyzing the concept of an enhancing vaccine, presenting objections to the epidemiological model base of the concept and, likewise, presenting data that contradict that concept.
July 13, 2017: Vaccine
https://www.readbyqxmd.com/read/28602602/pneumococcal-conjugate-vaccine-use-in-adults-addressing-an-unmet-medical-need-for-non-bacteremic-pneumococcal-pneumonia
#16
Heather L Sings
Streptococcus pneumoniae is a frequent cause of community acquired pneumonia (CAP), with the largest burden of disease attributed to non-bacteremic pneumonia. Due to the high persistent burden of disease, pneumococcal pneumonia, particularly non-bacteremic pneumococcal pneumonia, continues to be a major public health concern. There are currently two pneumococcal vaccines approved for use in adults in the United States (US) and other countries worldwide: a 23-valent pneumococcal simple polysaccharide vaccine (PPV23), and a 13-valent pneumococcal conjugate vaccine (PCV13)...
September 25, 2017: Vaccine
https://www.readbyqxmd.com/read/28577700/value-for-money-in-h1n1-influenza-a-systematic-review-of-the-cost-effectiveness-of-pandemic-interventions
#17
REVIEW
Hélène Pasquini-Descomps, Nathalie Brender, David Maradan
BACKGROUND: The 2009 A/H1N1 influenza pandemic generated additional data and triggered new studies that opened debate over the optimal strategy for handling a pandemic. The lessons-learned documents from the World Health Organization show the need for a cost estimation of the pandemic response during the risk-assessment phase. Several years after the crisis, what conclusions can we draw from this field of research? OBJECTIVE: The main objective of this article was to provide an analysis of the studies that present cost-effectiveness or cost-benefit analyses for A/H1N1 pandemic interventions since 2009 and to identify which measures seem most cost-effective...
June 2017: Value in Health: the Journal of the International Society for Pharmacoeconomics and Outcomes Research
https://www.readbyqxmd.com/read/28535854/influenza-a-world-of-discoveries-outbreaks-and-controversy
#18
Wendy S Barclay
Working in an area such as influenza is a free ticket into science communication, a pathway aided amply by the amazing evolutionary powers of the virus; regular outbreaks keep the media engaged and the audience keen. Everyone has heard of flu, and they probably already have an opinion: 'I don't take the vaccine, it gives me the flu anyway.' 'Didn't the government waste loads of money on that Tamiflu drug that doesn't work?' 'I've never had flu because I eat a banana every day and sleep with a boiled onion when I've sat next to someone on the train who was coughing...
May 2017: Journal of General Virology
https://www.readbyqxmd.com/read/28532186/bcg-and-protection-against-inflammatory-and-auto-immune-diseases
#19
Magdalena Kowalewicz-Kulbat, Camille Locht
Bacillus Calmette-Guérin (BCG) is the only available vaccine against tuberculosis. Although its protective efficacy against pulmonary tuberculosis is still under debate, it provides protection against other mycobacterial diseases. BCG is also an effective therapy against superficial bladder cancer and potentially decreases overall childhood mortality. Areas covered: The purpose of this paper is to provide a state-of-the-art summary of the beneficial effects of BCG in inflammatory and auto-immune diseases. As a strong inducer of Th1 type immunity, BCG has been reported to protect against atopic conditions, such as allergic asthma, a Th2-driven disorder...
July 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28515627/frequently-asked-questions-on-seven-rare-adverse-events-following-immunization
#20
REVIEW
G L D'alò, E Zorzoli, A Capanna, G Gervasi, E Terracciano, L Zaratti, E Franco
Routine mass immunization programs have contributed greatly to the control of infectious diseases and to the improvement of the health of populations. Over the last decades, the rise of antivaccination movements has threatened the advances made in this field to the point that vaccination coverage rates have decreased and outbreaks of vaccine-preventable diseases have resurfaced. One of the critical points of the immunization debate revolves around the level of risk attributable to vaccination, namely the possibility of experiencing serious and possibly irreversible adverse events...
March 2017: Journal of Preventive Medicine and Hygiene
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