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https://www.readbyqxmd.com/read/28445441/mining-productive-associated-periodic-frequent-patterns-in-body-sensor-data-for-smart-home-care
#1
Walaa N Ismail, Mohammad Mehedi Hassan
The understanding of various health-oriented vital sign data generated from body sensor networks (BSNs) and discovery of the associations between the generated parameters is an important task that may assist and promote important decision making in healthcare. For example, in a smart home scenario where occupants' health status is continuously monitored remotely, it is essential to provide the required assistance when an unusual or critical situation is detected in their vital sign data. In this paper, we present an efficient approach for mining the periodic patterns obtained from BSN data...
April 26, 2017: Sensors
https://www.readbyqxmd.com/read/28445151/trefoil-factor-3-mediation-of-oncogenicity-and-chemoresistance-in-hepatocellular-carcinoma-is-akt-bcl-2-dependent
#2
Ming-Liang You, Yi-Jun Chen, Qing-Yun Chong, Ming-Ming Wu, Vijay Pandey, Ru-Mei Chen, Liang Liu, Lan Ma, Zheng-Sheng Wu, Tao Zhu, Peter E Lobie
The efficacious treatment of hepatocellular carcinoma (HCC) remains a challenge, partially being attributed to intrinsic chemoresistance. Previous reports have observed increased TFF3 expression in HCC. Herein, we investigated the functional role of TFF3 in progression of HCC, and in both intrinsic and acquired chemoresistance. TFF3 expression was observed to be upregulated in HCC and associated with poor clinicopathological features and worse patient survival outcome. Functionally, forced expression of TFF3 in HCC cell lines increased cell proliferation, cell survival, anchorage-independent and 3D matrigel growth, cell invasion and migration, and in vivo tumor growth...
April 7, 2017: Oncotarget
https://www.readbyqxmd.com/read/28444827/fitness-costs-and-life-table-parameters-of-highly-insecticide-resistant-strains-of-plutella-xylostella-l-lepidoptera-plutellidae-at-different-temperatures
#3
Denise Steinbach, Gerald Moritz, Ralf Nauen
BACKGROUND: In many cases resistance alleles have been associated with fitness costs and are often dependent on environmental factors such as temperature. Here, we studied the effects of temperature on the overall fitness, including development, survival, and reproduction of three insecticide resistant and one susceptible strain of diamondback moth (DBM), Plutella xylostella (L.). RESULTS: The broader cross-resistance profile of the resistant strains previously selected by diamide and benzoylurea insecticides was tested...
April 26, 2017: Pest Management Science
https://www.readbyqxmd.com/read/28444434/quantitative-anatomy-of-the-primary-ossification-center-of-the-femoral-shaft-in-human-fetuses
#4
Mariusz Baumgart, Marcin Wiśniewski, Magdalena Grzonkowska, Mateusz Badura, Bogdan Małkowski, Michał Szpinda
PURPOSE: Early clinical distinction of congenital defects in the femur is extremely important, as it determines the prognosis of the development of the lower limb. This study was performed to quantitatively examine the primary center of ossification in the femoral shaft with respect to its linear, planar, and volumetric parameters. MATERIALS AND METHODS: Using methods of CT, digital-image analysis, and statistics, the size of the primary ossification center of the femoral shaft in 47 spontaneously aborted human fetuses aged 17-30 weeks was studied...
April 25, 2017: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/28443836/energy-harvesting-from-aperiodic-low-frequency-motion-using-reverse-electrowetting
#5
Tsung-Hsing Hsu, J A Taylor, T N Krupenkin
Mechanical energy harvesting can provide a promising alternative to electrochemical batteries, which are currently widely utilized to power mobile electronics. In this work we present a theoretical analysis of a recently proposed method of mechanical energy harvesting, which combines a reverse electrowetting phenomenon with the fast self-oscillating process of bubble growth and collapse. We investigate the details of the bubble dynamics and analyze the dependence of the energy generation process on the system parameters...
April 26, 2017: Faraday Discussions
https://www.readbyqxmd.com/read/28443589/significance-of-inverted-pattern-in-non-invasive-low-grade-papillary-urothelial-carcinoma-of-bladder
#6
Sehbal Arslankoz, İbrahim Kulaç, Dilek Ertoy Baydar
AIMS: The purpose of this study is to evaluate the impact of histological inverted pattern on recurrence in patients with newly diagnosed non-invasive low-grade papillary urothelial carcinoma of the urinary bladder. METHODS: A total of 81 patients with primary bladder non-invasive low-grade papillary urothelial carcinomadiagnosed in a single tertiary care center between 2000 and 2011 who had at least 1 year follow-up after an initial resection were included. All slides from each case were reviewed to determine the growth pattern (exophytic versus endophytic, i...
April 13, 2017: Balkan Medical Journal
https://www.readbyqxmd.com/read/28443291/a-review-of-the-development-of-tumor-vasculature-and-its-effects-on-the-tumor-microenvironment
#7
REVIEW
Jake C Forster, Wendy M Harriss-Phillips, Michael Jj Douglass, Eva Bezak
BACKGROUND: The imbalance of angiogenic regulators in tumors drives tumor angiogenesis and causes the vasculature to develop much differently in tumors than in normal tissue. There are several cancer therapy techniques currently being used and developed that target the tumor vasculature for the treatment of solid tumors. This article reviews the aspects of the tumor vasculature that are relevant to most cancer therapies but particularly to vascular targeting techniques. MATERIALS AND METHODS: We conducted a review of identified experiments in which tumors were transplanted into animals to study the development of the tumor vasculature with tumor growth...
2017: Hypoxia
https://www.readbyqxmd.com/read/28443259/the-different-effects-of-gonadotropin-releasing-hormone-agonist-therapy-on-body-mass-index-and-growth-between-normal-weight-and-overweight-girls-with-central-precocious-puberty
#8
Won Jun Yang, Keun Hyeok Ko, Kon Hee Lee, Il Tae Hwang, Yeon Joung Oh
PURPOSE: The effects of gonadotropin-releasing hormone agonist (GnRHa) treatment on body mass index (BMI) are controversial in girls with central precocious puberty (CPP). We therefore evaluated auxological parameters during GnRHa therapy in patients with CPP, specifically focusing on changes in BMI. METHODS: Seventy-seven girls with idiopathic CPP who underwent GnRHa therapy were retrospectively recruited. We investigated BMI changes during the treatment period after stratifying them according to baseline BMI status as follows: normal (BMI percentile of <85th) and overweight groups (BMI percentile of ≥85th)...
March 2017: Annals of Pediatric Endocrinology & Metabolism
https://www.readbyqxmd.com/read/28443166/correlation-between-topographic-parameters-obtained-by-back-surface-topography-based-on-structured-light-and-radiographic-variables-in-the-assessment-of-back-morphology-in-young-patients-with-idiopathic-scoliosis
#9
Laura Pino-Almero, María Fe Mínguez-Rey, Rosa María Cibrián-Ortiz de Anda, María Rosario Salvador-Palmer, Salvador Sentamans-Segarra
STUDY DESIGN: Optical cross-sectional study. PURPOSE: To study the correlation between asymmetry of the back (measured by means of surface topography) and deformity of the spine (quantified by the Cobb angle). OVERVIEW OF LITERATURE: The Cobb angle is considered the gold standard in diagnosis and follow-up of scoliosis but does not correctly characterize the three-dimensional deformity of scoliosis. Furthermore, the exposure to ionizing radiation may cause harmful effects particularly during the growth stage, including breast cancer and other tumors...
April 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28442723/effects-of-elevated-co2-on-the-fitness-and-potential-population-damage-of-helicoverpa-armigera-based-on-two-sex-life-table
#10
Jinping Liu, Wenkun Huang, Hsin Chi, Chonghui Wang, Hongxia Hua, Gang Wu
We evaluated the direct effects of three different atmospheric CO2 concentrations (380 ppm, 550 ppm and 750 ppm) on the population parameters of the cotton bollworm, Helicoverpa armigera fed an artificial diet. The life history and fitness of H. armigera were analyzed using an age-stage, two-sex life table. Our results showed significantly longer larval durations and lower female pupal weight under elevated CO2 than under ambient CO2. Additionally, the fecundity of H. armigera was lower under elevated CO2 than under ambient CO2...
April 25, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28442569/density-dependence-in-demography-and-dispersal-generates-fluctuating-invasion-speeds
#11
Lauren L Sullivan, Bingtuan Li, Tom E X Miller, Michael G Neubert, Allison K Shaw
Density dependence plays an important role in population regulation and is known to generate temporal fluctuations in population density. However, the ways in which density dependence affects spatial population processes, such as species invasions, are less understood. Although classical ecological theory suggests that invasions should advance at a constant speed, empirical work is illuminating the highly variable nature of biological invasions, which often exhibit nonconstant spreading speeds, even in simple, controlled settings...
April 25, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28442201/temporal-variations-in-physiological-responses-of-kandelia-obovata-seedlings-exposed-to-multiple-heavy-metals
#12
Shanshan Cheng, Nora Fung Yee Tam, Ruili Li, Xiaoxue Shen, Zhiyuan Niu, Minwei Chai, Guo Yu Qiu
A study was conducted to quantify temporal variations in physiological responses of Kandelia obovata under multiple heavy metal stress. The results showed that plant growth was not significantly affected by multiple heavy metal stress during the 120-days experiment. At the start, levels of net photosynthetic rate (Pn), stomatal conductance (Gs) and transpiration rate (Tr) showed effects of "low-promotion, high-inhibition", but Pn and Gs reduced with increasing heavy metal stress at the end. Temporary lipid oxidation was shown by high levels of malondialdehyde (MDA) under high heavy metal stress at the start but was unaffected at the end of the experiment...
April 22, 2017: Marine Pollution Bulletin
https://www.readbyqxmd.com/read/28441796/role-of-dietary-crocin-in-in-vivo-melanoma-tumor-remission
#13
Hamid A Bakshi, Faruck Lukmanul Hakkim, Smitha Sam, Farideh Javid
Background: Melanoma is a deadly form of malignancy. Early diagnosis might pave the way to cure but its aggressive nature leads to rapid dissemination and colonization of distant organs. Dietary herbs may play a significant role in prevention of cancer. In this study, we tested anti-tumor efficacy of the Crocus sativus derived active constituent crocin, well established to have anti-cancer properties in different cancer models by our group and other groups and other groups. Notably, crocin is reported to exert anti-proliferative effect on melanoma cells (B16F10) in vitro...
March 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28440853/antibiotic-strategies-for-eradicating-pseudomonas-aeruginosa-in-people-with-cystic-fibrosis
#14
REVIEW
Simon C Langton Hewer, Alan R Smyth
BACKGROUND: Respiratory tract infection with Pseudomonas aeruginosa occurs in most people with cystic fibrosis. Once chronic infection is established, Pseudomonas aeruginosa is virtually impossible to eradicate and is associated with increased mortality and morbidity. Early infection may be easier to eradicate.This is an update of a Cochrane review first published in 2003, and previously updated in 2006, 2009 and 2014. OBJECTIVES: To determine whether antibiotic treatment of early Pseudomonas aeruginosa infection in children and adults with cystic fibrosis eradicates the organism, delays the onset of chronic infection, and results in clinical improvement...
April 25, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28440792/an-extra-uterine-system-to-physiologically-support-the-extreme-premature-lamb
#15
Emily A Partridge, Marcus G Davey, Matthew A Hornick, Patrick E McGovern, Ali Y Mejaddam, Jesse D Vrecenak, Carmen Mesas-Burgos, Aliza Olive, Robert C Caskey, Theodore R Weiland, Jiancheng Han, Alexander J Schupper, James T Connelly, Kevin C Dysart, Jack Rychik, Holly L Hedrick, William H Peranteau, Alan W Flake
In the developed world, extreme prematurity is the leading cause of neonatal mortality and morbidity due to a combination of organ immaturity and iatrogenic injury. Until now, efforts to extend gestation using extracorporeal systems have achieved limited success. Here we report the development of a system that incorporates a pumpless oxygenator circuit connected to the fetus of a lamb via an umbilical cord interface that is maintained within a closed 'amniotic fluid' circuit that closely reproduces the environment of the womb...
April 25, 2017: Nature Communications
https://www.readbyqxmd.com/read/28440558/what-determines-organ-size-differences-between-species-a-meta-analysis-of-the-cellular-basis
#16
Ayelén Gázquez, Gerrit T S Beemster
Little is known about how the characteristic differences in organ size between species are regulated. At the cellular level, the size of an organ is strictly regulated by cell division and expansion during its development. We performed a meta-analysis of the growth parameters of roots, and Graminae and eudicotyledonous leaves, to address the question of how quantitative variation in these two processes contributes to size differences across a range of species. We extracted or derived cellular parameters from published kinematic growth analyses...
April 25, 2017: New Phytologist
https://www.readbyqxmd.com/read/28440426/downregulation-of-microrna-30d-promotes-cell-proliferation-and-invasion-by-targeting-lrh-1-in-colorectal-carcinoma
#17
Likun Yan, Jian Qiu, Jianfeng Yao
The aberrant expression of miR-30d has been reported in several types of human malignancies. However, its biological function in colorectal cancer (CRC) remains largely unknown. In this study, we identified that miR‑30d was significantly downregulated in CRC tissues compared to that observed in normal controls as detected by RT‑qPCR analysis. Downregulation of miR‑30d was significantly associated with aggressive clinicopathological parameters including tumor differentiation, invasive depth, TNM stage, lymph node metastasis, distant metastasis, and poor prognosis...
April 20, 2017: International Journal of Molecular Medicine
https://www.readbyqxmd.com/read/28440420/wound-healing-effect-of-an-astragalus%C3%A2-membranaceus-polysaccharide-and-its-mechanism
#18
Bingjiang Zhao, Xuanfen Zhang, Wei Han, Ju Cheng, Yonghong Qin
In the present study, a novel polysaccharide, APS2-1, was isolated and purified from Astragalus membranaceus using DEAE-cellulose and Sephadex G-100 chromatography. The effect of APS2‑1 on the promotion of wound healing was evaluated and its preliminary mechanism was investigated. In vitro experiments showed that APS2‑1 was able to promote human skin fibroblast (HSF) propagation and accelerate cell cycle progression. For further examination, a scalded mice model was used to verify the effect of APS2‑1 and investigate its mechanism of action...
April 20, 2017: Molecular Medicine Reports
https://www.readbyqxmd.com/read/28440077/molecular-dynamics-simulations-of-the-standard-leonardite-humic-acid-microscopic-analysis-of-the-structure-and-dynamics
#19
Drazen Petrov, Daniel Tunega, Martin H Gerzabek, Chris Oostenbrink
Humic substances (HS) are abundant in the environment and play an important role in a number of biogeochemical processes including microbial activity, soil aggregation, plant growth, the retention and release of nutrients, the environmental fate of pollutants and carbon storage. They are flexible, relatively small molecules forming supramolecular structures through weak interactions. Despite the great importance of understanding their behavior at the atomic level, computational modeling, a premier high-resolution technique providing great level of detail, has been surprisingly little employed to study humic substances...
April 25, 2017: Environmental Science & Technology
https://www.readbyqxmd.com/read/28439308/vertical-expandable-prosthetic-titanium-ribs-veptr-in-early-onset-scoliosis-impact-on-thoracic-compliance-and-sagittal-balance
#20
M R Konieczny, A-K Ehrlich, R Krauspe
BACKGROUND: Theoretically, dynamic thoracic compliance (DTC) should be reduced by vertical expandable prosthetic titanium ribs (VEPTR) since titanium rods, scar tissue and ossifications increase stiffness of the rib cage. The effect of VEPTR on thoracic compliance has not yet been elucidated. The impact of VEPTR on the development of sagittal balance has not been fully investigated. PATIENTS AND METHODS: In a retrospective study, we investigated 21 consecutive children who were treated by VEPTR from 2004 to 2011 and three control groups...
2017: Journal of Children's Orthopaedics
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