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https://www.readbyqxmd.com/read/29618856/a-learning-module-in-hair-restoration-surgery-a-simple-and-economic-method-to-learn-all-steps-of-strip-method-of-hair-follicles-harvesting-and-implantation
#1
Anil Kumar Garg, Seema Garg
Background: There is a global increase in demand for hair transplant as well as increasing demand for trained assistants and surgeons. It is a fact that permanent donor hair follicles are limited and any loss during learning is permanent and irreversible, so there is no place to learn and/or practice on a patient. Objective: To develop a learning module in hair restoration surgery to learn all steps of strip method of hair follicles harvesting and methods of implantation...
September 2017: Indian Journal of Plastic Surgery: Official Publication of the Association of Plastic Surgeons of India
https://www.readbyqxmd.com/read/29593497/reprogramming-glia-into-neurons-in-the-peripheral-auditory-system-as-a-solution-for-sensorineural-hearing-loss-lessons-from-the-central-nervous-system
#2
REVIEW
Steven J Meas, Chun-Li Zhang, Alain Dabdoub
Disabling hearing loss affects over 5% of the world's population and impacts the lives of individuals from all age groups. Within the next three decades, the worldwide incidence of hearing impairment is expected to double. Since a leading cause of hearing loss is the degeneration of primary auditory neurons (PANs), the sensory neurons of the auditory system that receive input from mechanosensory hair cells in the cochlea, it may be possible to restore hearing by regenerating PANs. A direct reprogramming approach can be used to convert the resident spiral ganglion glial cells into induced neurons to restore hearing...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29563738/reconstruction-of-the-major-defects-of-the-tissue-scalp
#3
M I Muradov, K B Mukhamedkerim, А А Baiguzeva, K E Kazantaev, D Zh Koshkarbaev
The problem of treating tissue defects of the scalp to date remains one of the actual problems of modern medicine. Low elasticity, stiffness, and the presence of hair follicles and skin deficit dictate the need for new treatments, cosmetic relevant requirements of this zone. The use of expander dermotension in recent years has found its wide distribution in the treatment of defects and deformities of covering tissue anywhere on the body. On the example of a patient K.32 years old hospitalized with diagnosis-basal cell epithelioma of the scalp-the defect of soft tissues, we demonstrated the use of expander plastic in the treatment of defect covering tissues of the scalp...
March 2018: Indian Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29543618/donor-site-assessment-for-female-hairline-restoration-in-southeast-asians
#4
Sittichai Ingprasert, Damkerng Pathomvanich, Patra Pinyopawasutthi
BACKGROUND: Female hairline restoration has increasingly been in demand for the past decade. However, no reports address the correlation between characteristics of hair at the hairline and at the donor area. OBJECTIVE: To assess follicular characteristics at the hairline and at the donor area including hair density, diameter, and their correlation. MATERIALS AND METHODS: One hundred one randomly selected Southeast Asian female volunteers were assessed for hairline and donor area characteristics...
March 13, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29535325/deafness-and-loss-of-cochlear-hair-cells-in-the-absence-of-thyroid-hormone-transporters-slc16a2-mct8-and-slc16a10-mct10
#5
David S Sharlin, Lily Ng, François Verrey, Theo J Visser, Ye Liu, Rafal T Olszewski, Michael Hoa, Heike Heuer, Douglas Forrest
Transmembrane proteins that mediate the cellular uptake or efflux of thyroid hormone potentially provide a key level of control over neurodevelopment. In humans, defects in one such protein, solute carrier SLC16A2 (MCT8) are associated with psychomotor retardation. Other proteins that transport the active form of thyroid hormone triiodothyronine (T3) or its precursor thyroxine (T4) have been identified in vitro but the wider significance of such transporters in vivo is unclear. The development of the auditory system requires thyroid hormone and the cochlea is a primary target tissue...
March 13, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29506337/superficial-temporal-artery-flap-for-reconstruction-of-complex-facial-defects-a-new-algorithm
#6
Tarek M Elbanoby, Serag M Zidan, Amr M Elbatawy, Gaber M Aly, Khallad Sholkamy
Background: A variety of island flaps can be based on the superficial temporal artery with variable tissue composition. They can be used for defect reconstruction, cavity resurfacing, facial hair restoration, or contracture release. Methods: Seventy-two patients underwent facial reconstruction using a superficial temporal artery island flap from October 2010 to October 2014. The defects had various etiologies, including trauma, burns, tumors, exposed hardware, and congenital causes...
March 5, 2018: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/29491655/follicular-unit-grafting-in-chronic-nonhealing-leg-ulcers-a-clinical-study
#7
Leelavathy Budamakuntla, Eswari Loganathan, Sacchidananda A Sarvajnamurthy, H V Nataraj
Introduction and Objectives: The restoration of the epithelium after injury takes place by migration of epithelial cells adjoining a wound or by centrifugal migration from hair follicles. To evaluate the feasibility and potential healing capacity of scalp follicular unit grafts transplanted into the wound bed of chronic leg ulcers. Materials and Methods: Patients with chronic nonhealing ulcers of more than 6 weeks duration were selected for the study. Those with infected ulcers and uncontrolled diabetes were excluded from the study...
October 2017: Journal of Cutaneous and Aesthetic Surgery
https://www.readbyqxmd.com/read/29484017/artificial-hair-by-the-dawn-to-automatic-biofibre%C3%A2-hair-implant
#8
REVIEW
Maria Roccia, Katlein França, David Castillo, Georgi Tchernev, Uwe Wollina, Michael Tirant, Yan Valle, Claudio Guarneri, Massimo Fioranelli, Torello Lotti
Since the beginning of the twentieth century, there have been attempts at creating artificial hair to treat baldness. Major evolution took place at the end of 1970's when, unfortunately, artificial hair treatments were applied without appropriate medical controls, resulting in sub-standard results from the use of unsuitable materials and technique. The large improper use of this technique in North America from no medical personnel and with dangerous fibres led the Food and Drug Administration (FDA) to suspend the procedure in 1983...
January 25, 2018: Open Access Macedonian Journal of Medical Sciences
https://www.readbyqxmd.com/read/29462020/pubic-hair-restorative-surgery-using-grafts-harvested-by-the-nonshaven-follicular-unit-extraction-technique
#9
NaRae Kim, Jae Hyun Park
BACKGROUND: Pubic atrichosis or hypotrichosis is quite common among Korean women. Although Korean people are increasingly opening up to Western culture, pubic hair transplantation is still pursued for cultural reasons. However, many hesitate to undergo restorative surgery because follicular unit strip surgery would leave a linear donor scar, preventing patients from hiding their surgical history. Thus, follicle harvesting using nonshaven follicular unit extraction (NS-FUE), aside from many other strengths, is very useful when performing pubic restorative surgery...
February 15, 2018: Dermatologic Surgery: Official Publication for American Society for Dermatologic Surgery [et Al.]
https://www.readbyqxmd.com/read/29461562/in-situ-tem-observation-of-rebonding-on-fractured-silicon-carbide
#10
Zhenyu Zhang, Junfeng Cui, Bo Wang, Haiyue Jiang, Guoxin Chen, Jinhong Yu, Chengte Lin, Chun Tang, Alexander Hartmaier, Junjie Zhang, Jun Luo, Andreas Rosenkranz, Nan Jiang, Dongming Guo
Silicon carbide (SiC) is widely used in harsh environments and under extreme conditions, including at high-power, high-temperature, high-current, high-voltage and high-frequency. The rebonding and self-matching of stack faults (SFs) is highly desirable to avoid catastrophic failure for SiC devices, especially for specific applications in the aerospace and nuclear power industries. In this study, a novel approach was developed using an eyebrow hair to pick up and transfer nanowires (NWs), in order to obtain in situ transmission electron microscope (TEM) images of the rebonding and self-matching of SFs at atomic resolution...
February 20, 2018: Nanoscale
https://www.readbyqxmd.com/read/29461376/modified-unilateral-pedicled-v-y-advancement-flap-for-scalp-defect-repair
#11
Hua Shen, Xinyi Dai, Jun Chen, Jing Wang, Zhaofen Zhang, Zhengdong Cai
Reconstruction of scalp defects caused by tumor resection or trauma is very challenging. A majority of the surgeons prefer to use local flap rather than skin graft or free flap for scalp defects repair. The aim of this study is to investigate the technique of modified unilateral pedicled V-Y advancement flap for the reconstruction of scalp defect.A retrospective review was performed in a series of 18 patients who had a modified unilateral pedicled V-Y advancement flap to restore scalp defect from May 2013 to January 2017...
February 14, 2018: Journal of Craniofacial Surgery
https://www.readbyqxmd.com/read/29457005/effectiveness-of-platelet-rich-plasma-for-androgenetic-alopecia-a-review-of-the-literature
#12
REVIEW
Jessica Cervantes, Marina Perper, Lulu L Wong, Ariel E Eber, Alexandra C Villasante Fricke, Tongyu Cao Wikramanayake, Joaquin J Jimenez
Androgenetic alopecia (AGA) is a hair loss disorder affecting 80% of men and 50% of women throughout their lifetime. Therapies for AGA are limited and there is no cure. There is a high demand for hair restoration. Platelet-rich plasma (PRP), a treatment modality shown to promote wound healing, has also been explored as a treatment for AGA. This literature review was conducted to assess the effectiveness of PRP treatment for AGA. Twelve studies conducted from 2011 to 2017 were evaluated and summarized by study characteristics, mode of preparation, and treatment protocols...
January 2018: Skin Appendage Disorders
https://www.readbyqxmd.com/read/29440850/a-meta-analysis-on-evidence-of-platelet-rich-plasma-for-androgenetic-alopecia
#13
Salvatore Giordano, Marco Romeo, Pietro di Summa, Andre' Salval, Petteri Lankinen
Background: Platelet-rich plasma (PRP) treatment has gained popularity among different surgical specialities for improving various conditions. Androgenetic alopecia (AGA) is a common disorder, with possible psychosocial implications. Plastic surgeons have increased the practice of PRP injections for hair restoration. A meta-analysis on this topic was performed comparing local injection of PRP versus control to investigate the efficacy of local PRP injections in AGA. Methods: We performed a systematic literature search...
January 2018: International Journal of Trichology
https://www.readbyqxmd.com/read/29424820/the-antioxidant-effect-of-rosmarinic-acid-by-different-delivery-routes-in-the-animal-model-of-noise-induced-hearing-loss
#14
Anna R Fetoni, Sara Letizia Maria Eramo, Antonella Di Pino, Rolando Rolesi, Fabiola Paciello, Claudio Grassi, Diana Troiani, Gaetano Paludetti
HYPOTHESIS: Trans-tympanic Rosmarinic Acid (RA), as compared with the systemic administration, protects against noise-induced auditory hair cell and hearing losses in rats in vivo. BACKGROUND: ROS production, lipoperoxidative damage, and an imbalance of antioxidant defences play a significant role in noise-induced hearing loss. Several molecules with antioxidant properties have been tested to restore redox homeostasis; however, drug delivery system represents a challenge for their effectiveness...
March 2018: Otology & Neurotology
https://www.readbyqxmd.com/read/29417383/targeted-heat-activation-of-hsp-promoters-in-the-skin-of-mammalian-animals-and-humans
#15
Richard Voellmy, Olivier Zürcher, Manon Zürcher, Pierre A de Viragh, Alexis K Hall, Stephen M Roberts
The use of highly inducible HSP promoters for exerting spatial and/or temporal control over the expression of therapeutic transgenes has long been discussed. Localized and time-limited induction of the heat shock response may potentially also be of medical interest. However, such applications would require targeted delivery of heat doses capable of activating HSP promoters in tissues or organs of interest. Accessible areas, including the skin and tissues immediately underneath it, may be most readily targeted...
February 7, 2018: Cell Stress & Chaperones
https://www.readbyqxmd.com/read/29413639/biotin-and-acetazolamide-for-treatment-of-an-unusual-child-with-autism-plus-lack-of-nail-and-hair-growth
#16
Paul J Benke, Michael Duchowny, Dianalee McKnight
BACKGROUND: Patients with autism spectrum disorder and developmental delay or encephalopathy rarely demonstrate no or negligible hair and nail growth, suggesting a biotin-responsive clinical disorder. METHODS: A ten-year-old girl presented with features of autism spectrum disorder, isolated headaches, and episodes of headaches and limb shaking. Her medical history revealed that her hair and nails did not grow. Administration of biotin restored her nail and hair growth and improved intellectual ability and school performance...
February 2018: Pediatric Neurology
https://www.readbyqxmd.com/read/29403358/novel-peptide-vaccine-gv1001-rescues-hearing-in-kanamycin-furosemide-treated-mice
#17
Shin Hye Kim, Gaon Jung, Sangjae Kim, Ja-Won Koo
The cell-penetrating peptide GV1001 has been investigated as an anticancer agent and recently demonstrated anti-oxidant and anti-inflammatory effects. It has shown a protective effect on a kanamycin (KM)-induced ototoxicity mouse model. In the present study, we administered GV1001 at different time points after inducing hair cell damage, and examined if it rescues hair cell loss and restores hearing. A deaf mouse model was created by intraperitoneal injection of KM and furosemide. First, to test the early temporal change of hearing and extent of hair cell damage after KM and furosemide injection, hearing and outer hair cells (OHCs) morphology were evaluated on day 1, day 2 and day 3 after injection...
2018: Frontiers in Cellular Neuroscience
https://www.readbyqxmd.com/read/29385890/unique-sensory-and-motor-behavior-in-thy1-gfp-m-mice-before-and-after-spinal-cord-injury
#18
Timothy D Faw, Jessica K Lerch, Tyler T Thaxton, Rochelle J Deibert, Lesley C Fisher, D Michele Basso
Sensorimotor recovery after spinal cord injury (SCI) is of utmost importance to injured individuals and will rely on improved understanding of SCI pathology and recovery. Novel transgenic mouse lines facilitate discovery, but must be understood to be effective. The purpose of this study was to characterize the sensory and motor behavior of a common transgenic mouse line (Thy1-GFP-M) before and after SCI. Thy1-GFP-M positive (TG+) mice and their transgene negative littermates (TG-) were acquired from two sources (in-house colony n=32, Jackson Laboratories n=4)...
January 31, 2018: Journal of Neurotrauma
https://www.readbyqxmd.com/read/29363542/ruxolitinib-protects-skin-stem-cells-and-maintains-skin-homeostasis-in-murine-graft-versus-host-disease
#19
Shuichiro Takahashi, Daigo Hashimoto, Eiko Hayase, Reiki Ogasawara, Hiroyuki Ohigashi, Takahide Ara, Emi Yokoyama, Ko Ebata, Satomi Matsuoka, Geoffrey Hill, Junichi Sugita, Masahiro Onozawa, Takanori Teshima
Graft-versus-host disease (GVHD) is the major complication after allogeneic stem cell transplantation (SCT). Emerging evidence indicates that GVHD leads to injury of intestinal stem cells. However, it remains to be investigated whether skin stem cells could be targeted in skin GVHD. Lgr5+ hair follicle stem cells (HFSCs) contribute to folliculogenesis and have a multipotent capacity to regenerate all epithelial cells in repair. We studied the fate of Lgr5+ HFSCs after SCT and explored the novel treatment to protect Lgr5+ HFSCs against GVHD using murine models of SCT...
January 23, 2018: Blood
https://www.readbyqxmd.com/read/29349046/reduction-of-closed-frontal-sinus-fractures-through-suprabrow-approach
#20
Hyung Min Hahn, Yoo Jung Lee, Myong Chul Park, Il Jae Lee, Sue Min Kim, Dong Ha Park
Background: The traditional approach for reduction of frontal sinus fractures is coronal incision. Inherent complications of the coronal approach include long scar, hair loss, and long operation time. We describe a simple approach for the reduction of frontal sinus anterior wall fractures using a suprabrow incision that is commonly used for brow lift. Methods: From March 2007 to October 2016, the authors identified patients with anterior wall frontal sinus fractures treated by open reduction through a suprabrow incision...
December 2017: Archives of Craniofacial Surgery
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