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auditory verbal hallucinations

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https://www.readbyqxmd.com/read/28625224/auditory-verbal-hallucinations-are-related-to-cortical-thinning-in-the-left-middle-temporal-gyrus-of-patients-with-schizophrenia
#1
Y Cui, B Liu, M Song, D M Lipnicki, J Li, S Xie, Y Chen, P Li, L Lu, L Lv, H Wang, H Yan, J Yan, H Zhang, D Zhang, T Jiang
BACKGROUND: Auditory verbal hallucinations (AVHs) are one of the most common and severe symptoms of schizophrenia, but the neuroanatomical abnormalities underlying AVHs are not well understood. The present study aims to investigate whether AVHs are associated with cortical thinning. METHODS: Participants were schizophrenia patients from four centers across China, 115 with AVHs and 93 without AVHs, as well as 261 healthy controls. All received 3 T T1-weighted brain scans, and whole brain vertex-wise cortical thickness was compared across groups...
June 19, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/28576898/sex-differences-in-auditory-verbal-hallucinations-in-early-middle-and-late-adolescence-results-from-a-survey-of-17-451-japanese-students-aged-12-18-years
#2
Yoko Morokuma, Kaori Endo, Atushi Nishida, Syudo Yamasaki, Shuntaro Ando, Yuko Morimoto, Miharu Nakanishi, Yuji Okazaki, Toshi A Furukawa, Shigeru Morinobu, Shinji Shimodera
OBJECTIVES: Women have higher rates of auditory verbal hallucinations (AVH) than men; however, less is known about sex differences in the prevalence of AVH in early, middle and late adolescence. We sought to elucidate the differences in the prevalence of AVH and to examine the degree to which these differences could be explained by differences in levels of depressive symptoms. DESIGN: We used a cross-sectional design and a self-reported questionnaire. SETTING: Participants were recruited from public junior and senior high schools in Tsu, Mie Prefecture and Kochi Prefecture, Japan...
June 1, 2017: BMJ Open
https://www.readbyqxmd.com/read/28572034/decreased-middle-temporal-gyrus-connectivity-in-the-language-network-in-schizophrenia-patients-with-auditory-verbal-hallucinations
#3
Linchuan Zhang, Baojuan Li, Huaning Wang, Liang Li, Qimei Liao, Yang Liu, Xianghong Bao, Wenlei Liu, Hong Yin, Hongbing Lu, Qingrong Tan
As the most common symptoms of schizophrenia, the long-term persistence of obstinate auditory verbal hallucinations (AVHs) brings about great mental pain to patients. Neuroimaging studies of schizophrenia have indicated that AVHs were associated with altered functional and structural connectivity within the language network. However, effective connectivity that could reflect directed information flow within this network and is of great importance to understand the neural mechanisms of the disorder remains largely unknown...
May 29, 2017: Neuroscience Letters
https://www.readbyqxmd.com/read/28562181/working-memory-predicts-presence-of-auditory-verbal-hallucinations-in-schizophrenia-and-bipolar-disorder-with-psychosis
#4
Lisanne M Jenkins, Anjuli S Bodapati, Rajiv P Sharma, Cherise Rosen
OBJECTIVE: The recent dramatic increase in research investigating auditory verbal hallucinations (AVHs) has broadened the former narrow focus on schizophrenia to incorporate additional populations that experience these symptoms. However, an understanding of potential shared mechanisms remains elusive. Based on theories suggesting a failure of top-down cognitive control, we aimed to compare the relationship between AVHs and cognition in two categorical diagnoses of psychosis, schizophrenia and psychotic bipolar disorder...
May 31, 2017: Journal of Clinical and Experimental Neuropsychology
https://www.readbyqxmd.com/read/28546056/glutamate-in-dorsolateral-prefrontal-cortex-and-auditory-verbal-hallucinations-in-patients-with-schizophrenia-a-1-h-mrs-study
#5
Branislava Ćurčić-Blake, Leonie Bais, Anita Sibeijn-Kuiper, Hendrika Maria Pijnenborg, Henderikus Knegtering, Edith Liemburg, André Aleman
PURPOSE: Glutamatergic models of psychosis propose that dysfunction of N-methyl-d-aspartate (NMDA) receptors, and associated excess of glutamate, may underlie psychotic experiences in people with schizophrenia. However, little is known about the specific relation between glutamate and auditory verbal hallucinations (AVH) in patients with psychosis. In this study, levels of glutamate+glutamine (Glx) in the left lateral prefrontal lobe were determined using proton magnetic resonance spectroscopy ((1)H MRS) to calculate their association with AVH...
May 22, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28532686/mismatch-negativity-mmn-to-spatial-deviants-and-behavioral-spatial-discrimination-ability-in-the-etiology-of-auditory-verbal-hallucinations-and-thought-disorder-in-schizophrenia
#6
Megan A Perrin, Joshua T Kantrowitz, Gail Silipo, Elisa Dias, Omar Jabado, Daniel C Javitt
Persistent auditory verbal hallucinations (AVH) in schizophrenia are increasingly tied to dysfunction at the level of auditory cortex. AVH may reflect in part misattribution of internally generated thoughts to external spatial locations. Here, we investigated the association between persistent AVH and spatial localization abilities assessed both behaviorally and by mismatch negativity (MMN) to location deviants. METHODS: Spatial- and tonal- discrimination abilities were assessed in patients (n=20) and controls (n=20) using free-field tones...
May 19, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28516807/neurofeedback-based-enhancement-of-single-trial-auditory-evoked-potentials-feasibility-in-healthy-subjects
#7
Kathryn Rieger, Marie-Helene Rarra, Nicolas Moor, Laura Diaz Hernandez, Anja Baenninger, Nadja Razavi, Thomas Dierks, Daniela Hubl, Thomas Koenig
Previous studies showed a global reduction of the event-related potential component N100 in patients with schizophrenia, a phenomenon that is even more pronounced during auditory verbal hallucinations. This reduction assumingly results from dysfunctional activation of the primary auditory cortex by inner speech, which reduces its responsiveness to external stimuli. With this study, we tested the feasibility of enhancing the responsiveness of the primary auditory cortex to external stimuli with an upregulation of the event-related potential component N100 in healthy control subjects...
May 1, 2017: Clinical EEG and Neuroscience: Official Journal of the EEG and Clinical Neuroscience Society (ENCS)
https://www.readbyqxmd.com/read/28497892/echoes-of-others-a-path-analytic-examination-of-an-interpersonal-cognitive-model-of-voice-related-distress
#8
Esther R Cole, Clara Strauss, Chris Fife-Schaw, Simon McCarthy-Jones
OBJECTIVES: Cognitive models propose that levels of distress associated with auditory verbal hallucinations ('voices') are influenced by the hearers' beliefs about their voices (perceived malevolence and omnipotence), their negative beliefs about themselves and others and their attachment style. This study aims to test a comprehensive model of the relationship between these variables in order to identify distal and proximal interpersonal and cognitive factors contributing to voice-related distress...
May 12, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28442422/effects-of-low-frequency-rtms-treatment-on-brain-networks-for-inner-speech-in-patients-with-schizophrenia-and-auditory-verbal-hallucinations
#9
Leonie Bais, Edith Liemburg, Ans Vercammen, Richard Bruggeman, Henderikus Knegtering, André Aleman
INTRODUCTION: Efficacy of repetitive Transcranial Magnetic Stimulation (rTMS) targeting the temporo-parietal junction (TPJ) for the treatment of auditory verbal hallucinations (AVH) remains under debate. We assessed the influence of a 1Hz rTMS treatment on neural networks involved in a cognitive mechanism proposed to subserve AVH. METHODS: Patients with schizophrenia (N=24) experiencing medication-resistant AVH completed a 10-day 1Hz rTMS treatment. Participants were randomized to active stimulation of the left or bilateral TPJ, or sham stimulation...
April 22, 2017: Progress in Neuro-psychopharmacology & Biological Psychiatry
https://www.readbyqxmd.com/read/28422354/auditory-verbal-experience-and-agency-in-waking-sleep-onset-rem-and-non-rem-sleep
#10
Jana Speth, Trevor A Harley, Clemens Speth
We present one of the first quantitative studies on auditory verbal experiences ("hearing voices") and auditory verbal agency (inner speech, and specifically "talking to (imaginary) voices or characters") in healthy participants across states of consciousness. Tools of quantitative linguistic analysis were used to measure participants' implicit knowledge of auditory verbal experiences (VE) and auditory verbal agencies (VA), displayed in mentation reports from four different states. Analysis was conducted on a total of 569 mentation reports from rapid eye movement (REM) sleep, non-REM sleep, sleep onset, and waking...
April 2017: Cognitive Science
https://www.readbyqxmd.com/read/28389551/on-shame-and-voice-hearing
#11
Angela Woods
Hearing voices in the absence of another speaker-what psychiatry terms an auditory verbal hallucination-is often associated with a wide range of negative emotions. Mainstream clinical research addressing the emotional dimensions of voice-hearing has tended to treat these as self-evident, undifferentiated and so effectively interchangeable. But what happens when a richer, more nuanced understanding of specific emotions is brought to bear on the analysis of distressing voices? This article draws findings from the 'What is it like to hear voices' study conducted as part of the interdisciplinary Hearing the Voice project into conversation with philosopher Dan Zahavi's Self and Other: Exploring Subjectivity, Empathy and Shame to consider how a focus on shame can open up new questions about the experience of hearing voices...
April 7, 2017: Medical Humanities
https://www.readbyqxmd.com/read/28347182/the-experience-of-voice-hearing-and-the-role-of-self-help-group-an-interpretative-phenomenological-analysis
#12
József Rácz, Zsuzsa Kaló, Szilvia Kassai, Márta Kiss, Judit Nóra Pintér
BACKGROUND: Auditory verbal hallucinations (AVHs) played an important role in the psychiatric diagnostics, but in the last few decades the diagnostic-free complex phenomenological understanding of the phenomena of voice hearing became the focus of studies. MATERIALS: Six semi-structured interviews with recovering voice hearers were conducted and analysed using interpretative phenomenological analysis (IPA). DISCUSSION: The self-help group gives significant help in identification and dealing with the voices; therefore, it serves as turning point in the life story of voice hearers...
March 1, 2017: International Journal of Social Psychiatry
https://www.readbyqxmd.com/read/28334963/three-and-four-dimensional-mapping-of-speech-and-language-in-patients-with-epilepsy
#13
Yasuo Nakai, Jeong-Won Jeong, Erik C Brown, Robert Rothermel, Katsuaki Kojima, Toshimune Kambara, Aashit Shah, Sandeep Mittal, Sandeep Sood, Eishi Asano
We have provided 3-D and 4D mapping of speech and language function based upon the results of direct cortical stimulation and event-related modulation of electrocorticography signals. Patients estimated to have right-hemispheric language dominance were excluded. Thus, 100 patients who underwent two-stage epilepsy surgery with chronic electrocorticography recording were studied. An older group consisted of 84 patients at least 10 years of age (7367 artefact-free non-epileptic electrodes), whereas a younger group included 16 children younger than age 10 (1438 electrodes)...
March 16, 2017: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/28277308/children-seeking-help-for-auditory-verbal-hallucinations-who-are-they
#14
Kim Maijer, Saskia J M C Palmen, Iris E C Sommer
BACKGROUND: Auditory Verbal Hallucinations (AVH) in children and adolescents are a relatively common and mostly transient feature in community samples. However, it should not be regarded as a merely benign phenomenon, as childhood AVH are associated with psychopathology. Little is known about the clinical group of children seeking help for AVH. This brings uncertainty on how to assess and treat these children. METHODS: This study describes the characteristics of 95 help-seeking children (aged 6 to 18years) with AVH attending an outpatient clinic specifically dedicated to help youth with this complaint...
October 27, 2016: Schizophrenia Research
https://www.readbyqxmd.com/read/28224285/abnormal-effective-connectivity-in-the-brain-is-involved-in-auditory-verbal-hallucinations-in-schizophrenia
#15
Baojuan Li, Long-Biao Cui, Yi-Bin Xi, Karl J Friston, Fan Guo, Hua-Ning Wang, Lin-Chuan Zhang, Yuan-Han Bai, Qing-Rong Tan, Hong Yin, Hongbing Lu
Information flow among auditory and language processing-related regions implicated in the pathophysiology of auditory verbal hallucinations (AVHs) in schizophrenia (SZ) remains unclear. In this study, we used stochastic dynamic causal modeling (sDCM) to quantify connections among the left dorsolateral prefrontal cortex (inner speech monitoring), auditory cortex (auditory processing), hippocampus (memory retrieval), thalamus (information filtering), and Broca's area (language production) in 17 first-episode drug-naïve SZ patients with AVHs, 15 without AVHs, and 19 healthy controls using resting-state functional magnetic resonance imaging...
June 2017: Neuroscience Bulletin
https://www.readbyqxmd.com/read/28203084/use-of-transcranial-direct-current-stimulation-for-the-treatment-of-auditory-hallucinations-of-schizophrenia-a-systematic-review
#16
REVIEW
Pedro H Pondé, Eduardo P de Sena, Joan A Camprodon, Arão Nogueira de Araújo, Mário F Neto, Melany DiBiasi, Abrahão Fontes Baptista, Lidia Mvr Moura, Camila Cosmo
INTRODUCTION: Auditory hallucinations are defined as experiences of auditory perceptions in the absence of a provoking external stimulus. They are the most prevalent symptoms of schizophrenia with high capacity for chronicity and refractoriness during the course of disease. The transcranial direct current stimulation (tDCS) - a safe, portable, and inexpensive neuromodulation technique - has emerged as a promising treatment for the management of auditory hallucinations. OBJECTIVE: The aim of this study is to analyze the level of evidence in the literature available for the use of tDCS as a treatment for auditory hallucinations in schizophrenia...
2017: Neuropsychiatric Disease and Treatment
https://www.readbyqxmd.com/read/28187965/impact-of-rtms-on-functional-connectivity-within-the-language-network-in-schizophrenia-patients-with-auditory-hallucinations
#17
F Briend, E Leroux, N Delcroix, A Razafimandimby, O Etard, S Dollfus
This exploratory study investigated the functional connectivity (FC) in the language network in schizophrenia patients (SZ) with auditory verbal hallucinations (AVHs), and the therapeutic efficacy of rTMS on it. Eleven SZ with AVHs and 10 healthy controls (HC) underwent two fMRI sessions using a speech listening paradigm. SZ received 20Hz rTMS following the first fMRI session. Compared to HC, SZ showed a reduced FC in the language network. While AVHs improved after 12days, no changes in FC were observed. This suggests the efficacy of high-frequency rTMS on AVH without any impact for rTMS on FC within the language network...
February 8, 2017: Schizophrenia Research
https://www.readbyqxmd.com/read/28167329/the-role-of-set-shifting-in-auditory-verbal-hallucinations
#18
Sara Siddi, Donatella Rita Petretto, Caterina Burrai, Rosanna Scanu, Antonella Baita, Pierfranco Trincas, Emanuela Trogu, Liliana Campus, Augusto Contu, Antonio Preti
BACKGROUND: Auditory verbal hallucinations (AVHs) are a cardinal characteristic of psychosis. Recent research on the neuropsychological mechanism of AVHs has focused on source monitoring failure, but a few studies have suggested the involvement of attention, working memory, processing speed, verbal learning, memory, and executive functions. In this study we examined the neuropsychological profile of patients with AVHs, assuming that the mechanism underlying this symptom could be a dysfunction of specific cognitive domains...
January 21, 2017: Comprehensive Psychiatry
https://www.readbyqxmd.com/read/28141710/the-curse-of-the-dolphins-cognitive-decline-and-psychosis
#19
Randall Phelps, Anne Tsai, Arlene Hagen, Joseph Pinter, Raegan Smith, Martin T Stein
Isela is an 11-year-old Mexican-American girl with mild intellectual disability. During a vacation with her family, she went swimming with dolphins. A few days later, Isela awoke at night with laughing spells; during the day, she was pacing, aggressive, and had a decline in self-care and communication skills. Her parents attributed the symptoms to the dolphins. She was evaluated by a pediatric neurologist. The sleep-deprived electroencephalogram, brain magnetic resonance imaging, lumbar puncture, and thyroid function tests were normal...
February 2017: Journal of Developmental and Behavioral Pediatrics: JDBP
https://www.readbyqxmd.com/read/28139359/altered-amplitude-of-low-frequency-fluctuations-in-schizophrenia-patients-with-persistent-auditory-verbal-hallucinations
#20
Anna Alonso-Solís, Yolanda Vives-Gilabert, Maria J Portella, Mireia Rabella, Eva M Grasa, Alexandra Roldán, Alejandro Keymer-Gausset, Conrad Molins, Fidel Núñez-Marín, Beatriz Gómez-Ansón, Enric Alvarez, Iluminada Corripio
The aim of this study is to analyze the differences in low frequency fluctuation (LFF) values between schizophrenia patients with and without auditory verbal hallucinations (AVH). Nineteen schizophrenia patients with persistent AVH (HP), fourteen non-hallucinating schizophrenia patients (nHP) and twenty healthy controls (HC) underwent R-fMRI. LFF values were calculated in the slow frequency band (0.01-0.08Hz). By means of group level contrasts, we performed direct voxel-wise group comparisons. Both groups of patients showed decreased amplitude LFF (ALFF) values in the occipital pole and lingual gyrus compared to HC, whereas increased ALFF values were found in the temporal pole and fusifom gyrus...
January 28, 2017: Schizophrenia Research
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