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https://www.readbyqxmd.com/read/29471538/novel-roles-of-ascorbate-in-plants-induction-of-cytosolic-ca2-signals-and-efflux-from-cells-via-anion-channels
#1
M Makavitskaya, D Svistunenko, I Navaselsky, P Hryvusevich, V Mackievic, C Rabadanova, E Tyutereva, V Samokhina, D Straltsova, A Sokolik, O Voitsekhovskaja, V Demidchik
Ascorbate is not often considered as a signalling molecule in plants. This study demonstrates that, in Arabidopsis roots, exogenous L-ascorbic acid triggers a transient increase of the cytosolic free calcium activity ([Ca2+]cyt.) that is central to plant signalling. Exogenous copper and iron stimulates the ascorbate-induced [Ca2+]cyt. elevation while cation channel blockers, free radical scavengers, low extracellular [Ca2+], transition metal chelators and removal of the cell wall inhibit this reaction. These data show that apoplastic redox-active transition metals are involved in the ascorbate-induced [Ca2+]cyt...
February 17, 2018: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29471525/rightsizing-root-phenotypes-for-drought-resistance
#2
Jonathan P Lynch
I propose that reduced root development would be advantageous for drought resistance in high-input agroecosystems. Selection regimes for crop ancestors and landraces include multiple stresses, intense competition, and variable resource distribution, which favored prolific root production, developmental plasticity in response to resource availability, and maintenance of unspecialized root tissues. High-input agroecosystems have removed many of these constraints to root function. Therefore, root phenotypes that focus on water capture at the expense of ancestral adaptations would be better suited to high-input agroecosystems...
February 17, 2018: Journal of Experimental Botany
https://www.readbyqxmd.com/read/29471488/morphological-responses-of-plant-roots-to-mechanical-stress
#3
Izabela Potocka, Joanna Szymanowska-Pulka
Background: Roots are continuously exposed to mechanical pressure and this often results in their morphological modification. Most obvious are changes in the overall form of the root system as well as in the shapes of particular roots. These changes are often accompanied by modifications of the cell pattern and cell morphology. Scope: This review focuses on the morphological responses of roots to mechanical stress. Results of early and recent experiments in which roots have been exposed to mechanical pressure are assembled, analysed and discussed...
February 17, 2018: Annals of Botany
https://www.readbyqxmd.com/read/29471454/the-impact-of-using-different-reference-populations-on-measurement-of-breast-cancer-related-cognitive-impairment-rates
#4
Jonathan D Clapp, George Luta, Brent J Small, Tim A Ahles, James C Root, Deena Graham, Arti Hurria, Paul B Jacobsen, Heather Jim, Brenna C McDonald, Robert A Stern, Andrew J Saykin, Jeanne S Mandelblatt
Objective: To evaluate how use of different reference populations affects estimates of breast cancer-related cognitive impairment rates. Methods: Patients aged ≥60 years with stage 0-3 breast cancer (n = 371) and matched non-cancer controls (n = 370) completed 13 neuropsychological tests prior to systemic therapy or at enrollment (controls). The tests captured three domains: attention, processing speed and executive function; learning and memory; and visual-spatial function...
February 17, 2018: Archives of Clinical Neuropsychology: the Official Journal of the National Academy of Neuropsychologists
https://www.readbyqxmd.com/read/29471279/sequenced-ascorbate-proline-glutathione-seed-treatment-elevates-cadmium-tolerance-in-cucumber-transplants
#5
Wael M Semida, Khaulood A Hemida, Mostafa M Rady
During its life cycle, plant has to cope with a number of abiotic stresses including cadmium stress. Cadmium (Cd) is highly toxic to plant and greatly influences its growth and entire metabolism. Antioxidants have to enable plant to beat such stresses. Therefore, effects of ascorbate (AsA), proline (Pro) and glutathione (GSH) applied, as seed soaking solutions, singly or in a sequence on cucumber transplant growth, physio-biochemical attributes and antioxidant defense system activity were investigated under 2 mM Cd stress...
February 19, 2018: Ecotoxicology and Environmental Safety
https://www.readbyqxmd.com/read/29471211/exogenous-nanosilica-improves-germination-and-growth-of-cucumber-by-maintaining-k-na-ratio-under-elevated-na-stress
#6
Abdullah Alsaeedi, Hassan El-Ramady, Tarek Alshaal, Mohamed El-Garawani, Nevien Elhawat, Awadh Al-Otaibi
The current work was aimed to elucidate the role of engineered nanosilica (SiNPs) particles to mitigate the damaging impacts of Na+ -derived salinity on cucumber (Cucumis sativus) Beit Alpha variety by conducting in vitro experiments applying various Na+ concentrations i.e. 0, 1000, 2000, 3000, 4000 and 5000 mg L-1 . By treating seeds and seedlings, respectively, of cucumber with SiNPs (0, 100, 200 and 300 ppm) and subsequent determination some germination and vegetative parameters as well as chemical analysis of seedlings, we verified that SiNPs succeeded to alleviate the detrimental effects of high Na+ salinity by increasing germination parameters and vegetative growth of cucumber seedlings...
February 9, 2018: Plant Physiology and Biochemistry: PPB
https://www.readbyqxmd.com/read/29471188/developing-cross-validating-and-applying-regression-models-to-predict-the-concentrations-of-faecal-indicator-organisms-in-coastal-waters-under-different-environmental-scenarios
#7
Robson V de Souza, Carlos J A Campos, Luis H P Garbossa, Walter Q Seiffert
This study developed, cross-validated and applied a regression-based model to predict concentrations of faecal indicator organisms (FIOs) under different environmental conditions in the North and South bays of Santa Catarina, South of Brazil. The model was developed using a database of FIO concentrations in seawater sampled at 50 sites and the validation was performed using a different database by comparing 288 pairs of measured and modelled results for 15 sites. The index of agreement between the model outputs and the FIO concentrations measured during the validation period was 66%; the mean average error was 0...
February 19, 2018: Science of the Total Environment
https://www.readbyqxmd.com/read/29471149/is-adjunctive-photodynamic-therapy-more-effective-than-scaling-and-root-planing-alone-in-the-treatment-of-periodontal-disease-in-hyperglycemic-patients-a-systematic-review
#8
REVIEW
Fawad Javed, Danial Salehpoor, Talal Al-Dhafeeri, Muhammad Yousuf, Hans Malmstrom, Junad Khan, Zohaib Akram
BACKGROUND: To assess the impact of scaling and root planing (SRP) with and without adjunct photodynamic therapy (PDT) in the treatment of periodontal disease (PD) in hyperglycemic patients. METHODS: Databases (MEDLINE, EMBASE; and CENTRAL) were searched up to December 2017. The addressed PICO question was: "What is the effectiveness of adjunctive PDT to non-surgical periodontal treatment by means of clinical periodontal and glycemic parameters in hyperglycemic patients?" RESULTS: Four clinical trials and 1 experimental study were included...
February 19, 2018: Photodiagnosis and Photodynamic Therapy
https://www.readbyqxmd.com/read/29471108/redox-stress-in-marfan-syndrome-dissecting-the-role-of-the-nadph-oxidase-nox4-in-aortic-aneurysm
#9
Francesc Jiménez-Altayó, Thayna Meirelles, Eva Crosas-Molist, M Alba Sorolla, Darya Gorbenko Del Blanco, Judit López-Luque, Aleksandra Mas-Stachurska, Ana-Maria Siegert, Fabio Bonorino, Laura Barberà, Carolina García, Enric Condom, Marta Sitges, Fernando Rodríguez-Pascual, Francisco Laurindo, Katrin Schröder, Joaquim Ros, Isabel Fabregat, Gustavo Egea
Marfan syndrome (MFS) is characterized by the formation of ascending aortic aneurysms resulting from altered assembly of extracellular matrix fibrillin-containing microfibrils and dysfunction of TGF-β signaling. Here we identify the molecular targets of redox stress in aortic aneurysms from MFS patients, and investigate the role of NOX4, whose expression is strongly induced by TGF-β, in aneurysm formation and progression in a murine model of MFS. Working models included aortae and cultured vascular smooth muscle cells (VSMC) from MFS patients, and a NOX4-deficient Marfan mouse model (Fbn1C1039G/+ -Nox4-/- )...
February 19, 2018: Free Radical Biology & Medicine
https://www.readbyqxmd.com/read/29471086/gastroprotective-effect-of-ethanol-extracts-of-cladodes-and-roots-of-pilosocereus-gounellei-a-weber-ex-k-schum-bly-ex-rowl-cactaceae-on-experimental-ulcer-models
#10
Glaubert A Sousa, Irisdalva S Oliveira, Francilene V Silva-Freitas, Ana Flávia S C Viana, Benedito P S Neto, Francisco Valmor M Cunha, Rodrigo L G Gonçalves, Antônio Carlos M Lima Filho, Maurício P M Amaral, Rita de Cássia M Oliveira, Pedro D Fernandes, Jéssica K S Maciel, Tânia Maria S da Silva, Maria de Fátima V Souza, Francisco A Oliveira
ETHNOPHARMACOLOGICAL RELEVANCE: Pilosocereus gounellei Cactaceae), popularly known as "xique xique", is a species native from Caatinga region of Northeast Brazil, which is used by traditional communities in folk medicine for a variety of health problems, especially inflammatory processes and gastritis. AIM OF THE STUDY: The present study investigates the possible gastric antiulceractivity of ethanol extracts obtained from the cladodes and roots of Pilosocereus gounellei (EECPG and EERPG, respectively) and mechanisms of action underlying this effect...
February 19, 2018: Journal of Ethnopharmacology
https://www.readbyqxmd.com/read/29471016/sensitivity-to-psychosocial-chronic-stressors-and-adolescents-externalizing-problems-combined-moderator-effects-of-resting-heart-rate-and-parental-psychiatric-history
#11
Anna Roos E Zandstra, Johan Ormel, Andrea Dietrich, Edwin R van den Heuvel, Pieter J Hoekstra, Catharina A Hartman
From the literature it is not clear whether low resting heart rate (HR) reflects low or high sensitivity to the detrimental effects of adverse environments on externalizing problems. We studied parental psychiatric history (PH), reflecting general vulnerability, as possible moderator explaining these inconsistencies. Using Linear Mixed Models, we analyzed data from 1914 subjects, obtained in three measurement waves (mean age 11, 13.5, and 16 years) from the TRacking Adolescents' Individual Lives Survey population-based cohort and the parallel clinic-referred cohort...
February 19, 2018: Biological Psychology
https://www.readbyqxmd.com/read/29470862/arabidopsis-hipp27-is-a-host-susceptibility-gene-for-the-beet-cyst-nematode-heterodera-schachtii
#12
Zoran S Radakovic, Muhammad Shahzad Anjam, Elizabeth Escobar, Divykriti Chopra, Javier Cabrera, Ana Cláudia Silva, Carolina Escobar, Miroslaw Sobczak, Florian M W Grundler, Shahid Siddique
Sedentary plant-parasitic cyst nematodes are obligate biotrophs that infect the roots of their host plant. Their parasitism is based on modification of root cells to form a hypermetabolic syncytium from which the nematodes draw their nutrients. The aim of this study was to identify nematode susceptibility genes in Arabidopsis thaliana and to characterize their roles in supporting the parasitism of Heterodera schachtii. By selecting genes that were most strongly upregulated in response to cyst nematode infection, we identified HIPP27 (HEAVY METAL-ASSOCIATED ISOPRENYLATED PLANT PROTEIN 27) as a host susceptibility factor required for beet cyst nematode infection and development...
February 22, 2018: Molecular Plant Pathology
https://www.readbyqxmd.com/read/29470810/diversity-of-anopheles-spp-diptera-culicidae-in-an-amazonian-urban-area
#13
I C Reis, C T Codeço, D C P Câmara, J J Carvajal, G R Pereira, E C Keppeler, N A Honório
The genus Anopheles encompasses several species considered as vectors of human infecting Plasmodium. Environmental changes are responsible for behavior changes in these vectors and therefore the pattern of malaria transmission. To better understand the dynamics of malaria transmission, this study aimed at identify the species of adult anophelines found in a malaria endemic urban area of the Amazon region, Mâncio Lima, located in the Acre State Brazil. Using Shannon-type light traps installed at 11 collection points near fish ponds, a total of 116 anophelines were collected belonging to nine species...
February 22, 2018: Neotropical Entomology
https://www.readbyqxmd.com/read/29470713/health-related-quality-of-life-in-patients-undergoing-cervico-thoracic-osteotomies-for-fixed-cervico-thoracic-kyphosis-in-patients-with-ankylosing-spondylitis
#14
Silviu Sabou, Hossein Mehdian, Dritan Pasku, Luca Boriani, Nasir A Quraishi
PURPOSE: Ankylosing spondylitis (AS) can result in severe cervico-thoracic kyphotic deformity (CTKD). Few studies have addressed the relationship between cervico-thoracic osteotomies in AS and health-related quality of life scores. The aim of this study is to evaluate the impact of cervico-thoracic osteotomy (CTO) on improving quality of life for patients with fixed CTKD. METHODS: A database of all patients who underwent a CTO for CTKD in patients with AS was created...
February 22, 2018: European Spine Journal
https://www.readbyqxmd.com/read/29470649/structural-arrangement-of-the-intrinsic-muscles-of-the-tongue-and-their-relationships-with-the-extrinsic-muscles
#15
Yujiro Sakamoto
The tongue is a dense muscular organ, in which the muscles are arranged in a confusing pattern. The intrinsic muscles were gross anatomically investigated in 25 cadavers to clarify their configuration. The superior longitudinal muscle (SLm) ran beneath the dorsal mucosa and was divided into bundles by the other muscles passing through it to the dorsum. The external bundle of the styloglossus, with the palatoglossus, coursed externally to the hyoglossus. Their fibers spread beneath the SLm or attached to the apex and the inferior longitudinal muscle (ILm) ascended from the root and joined them...
February 22, 2018: Surgical and Radiologic Anatomy: SRA
https://www.readbyqxmd.com/read/29470428/determining-forest-duff-water-content-using-a-low-cost-standing-wave-ratio-sensor
#16
Xiaofei Yan, Yajie Zhao, Qiang Cheng, Xiaoliang Zheng, Yandong Zhao
Forest duff (fermentation and humus) water content is an important parameter for fire risk prediction and water resource management. However, accurate determination of forest duff water content is difficult due to its loose structure. This study evaluates the feasibility of a standing wave ratio (SWR) sensor to accurately determine the forest duff water content. The performance of this sensor was tested on fermentation and humus with eight different compaction levels. Meanwhile, a commercialized time domain reflectometry (TDR) was employed for comparison...
February 22, 2018: Sensors
https://www.readbyqxmd.com/read/29470418/tetrodotoxin-a-candidate-drug-for-nav1-1-induced-mechanical-pain
#17
César Mattei
Tetrodotoxin (TTX), the mode of action of which has been known since the 1960s, is widely used in pharmacology as a specific inhibitor of voltage-gated sodium channels (Nav channels). This toxin has contributed to the characterization of the allosteric model of the Nav channel, and to discriminating TTX-sensitive and TTX-resistant subtypes. In addition to its role as a pharmacological tool, TTX is now considered a therapeutic molecule, and its development should lead to its use in certain pathologies involving Nav channels, particularly in the field of pain...
February 22, 2018: Marine Drugs
https://www.readbyqxmd.com/read/29470276/anatomical-feasibility-of-extradural-transferring-s2-and-s3-ventral-roots-to-s1-ventral-root-for-restoring-neurogenic-bladder-in-spinal-cord-injury
#18
Kaixiang Yang, Hongtao Chen, Jian Tang, Dawei Ge, Sheng Zhang, Tao Sui, Xiaojian Cao
STUDY DESIGN: Anatomic study in 6 formalin-fixed cadavers. OBJECTIVE: To determine the anatomical feasibility of transferring the S2 and S3 ventral roots (VRs) to S1 VR as a method for restoring bladder dysfunction in spinal cord injury. SUMMARY OF BACKGROUND DATA: A large quantity of researches of neuroanastomosis methods have been used for treating the bladder dysfunction in spinal cord injury (SCI). However, some limitations retard the development of those studies...
February 21, 2018: Spine
https://www.readbyqxmd.com/read/29470174/antidiabetic-and-protective-effects-of-the-aqueous-extract-of-arbutus-unedo-l-in-streptozotocin-nicotinamide-induced-diabetic-mice
#19
Hanae Naceiri Mrabti, Karima Sayah, Nidal Jaradat, Faouzi Kichou, Abdelaziz Ed-Dra, Badiaa Belarj, Yahia Cherrah, My El Abbes Faouzi
Background Diabetes mellitus (DM) is currently a major health problem and the most common chronic disease worldwide. Traditional medicinal plants remedies remain a potential adjunct therapy to maintain better glycemic control while also imparting few side-effects. Arbutus unedo L. has been traditionally used to manage several diseases including diabetes. This study was undertaken to contribute the validation of the traditional use of Arbutus unedoL. (Ericaceae) in the treatment of diabetes. Methods In-vitro antidiabetic effect of the A...
February 21, 2018: Journal of Complementary & Integrative Medicine
https://www.readbyqxmd.com/read/29470086/computational-study-on-n-n-homolytic-bond-dissociation-enthalpies-of-hydrazine-derivatives
#20
Yuanyuan Zheng, Wenrui Zheng, Jiaoyang Wang, Huifang Chang, Danfeng Zhu
The hydrazine derivatives have been regarded as the important building blocks in organic chemistry for the synthesis of organic N-containing compounds. It is important to understand the structure-activity relationship of the thermodynamics of N-N bonds, in particular, their strength as measured by using the homolytic bond dissociation enthalpies (BDEs). We calculated the N-N BDEs of 13 organonitrogen compounds by 8 composite high-level ab initio methods including G3, G3B3, G4, G4MP2, CBS-QB3, ROCBS-QB3, CBS-Q and CBS-APNO...
February 22, 2018: Journal of Physical Chemistry. A
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