keyword
MENU ▼
Read by QxMD icon Read
search

Tropics

keyword
https://www.readbyqxmd.com/read/28545225/state-of-art-of-cancer-pharmacogenomics-in-latin-american-populations
#1
REVIEW
Andrés López-Cortés, Santiago Guerrero, María Ana Redal, Angel Tito Alvarado, Luis Abel Quiñones
Over the past decades, several studies have shown that tumor-related somatic and germline alterations predicts tumor prognosis, drug response and toxicity. Latin American populations present a vast geno-phenotypic diversity due to the great interethnic and interracial mixing. This genetic flow leads to the appearance of complex characteristics that allow individuals to adapt to endemic environments, such as high altitude or extreme tropical weather. These genetic changes, most of them subtle and unexplored, could establish a mutational profile to develop new pharmacogenomic therapies specific for Latin American populations...
May 23, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28545188/clinacanthus-nutans-hexane-extracts-induce-apoptosis-through-a-caspase-dependent-pathway-in-human-cancer-cell-lines
#2
Pei Ying Ng, Soi Moi Chye, Chew Hee Ng, Rhun Yian Koh, Yee Lian Tiong, Liew Phing Pui, Yong Hui Tan, Crystale Siew Ying Lim, Khuen Yen Ng
Background: Clinacanthus nutans (C.nutans) is a plant consumed as a cancer treatment in tropical Asia. Despite the availability of numerous anecdotal reports, evaluation of active anticancer effects has remained elusive. Therefore we here examined antiproliferative, reactive oxygen species (ROS)-inducing and apoptosis mechanisms of whole plant extracts in different cancer cell lines. Methods: Antiproliferative actions of five solvent extracts (hexane, chloroform, ethyl acetate, methanol and water) of C.nutans were tested on non-small cell lung cancer (A549), nasopharygeal cancer (CNE1) and liver cancer (HepG2) cells using MTT assay...
April 1, 2017: Asian Pacific Journal of Cancer Prevention: APJCP
https://www.readbyqxmd.com/read/28545155/rapid-diagnostic-tests-for-typhoid-and-paratyphoid-enteric-fever
#3
REVIEW
Lalith Wijedoru, Sue Mallett, Christopher M Parry
BACKGROUND: Differentiating both typhoid (Salmonella Typhi) and paratyphoid (Salmonella Paratyphi A) infection from other causes of fever in endemic areas is a diagnostic challenge. Although commercial point-of-care rapid diagnostic tests (RDTs) for enteric fever are available as alternatives to the current reference standard test of blood or bone marrow culture, or to the widely used Widal Test, their diagnostic accuracy is unclear. If accurate, they could potentially replace blood culture as the World Health Organization (WHO)-recommended main diagnostic test for enteric fever...
May 26, 2017: Cochrane Database of Systematic Reviews
https://www.readbyqxmd.com/read/28545092/are-thermal-barriers-higher-in-deep-sea-turtle-nests
#4
Pilar Santidrián Tomillo, Luis Fonseca, Frank V Paladino, James R Spotila, Daniel Oro
Thermal tolerances are affected by the range of temperatures that species encounter in their habitat. Daniel Janzen hypothesized in his "Why mountain passes are higher in the tropics" that temperature gradients were effective barriers to animal movements where climatic uniformity was high. Sea turtles bury their eggs providing some thermal stability that varies with depth. We assessed the relationship between thermal uniformity and thermal tolerance in nests of three species of sea turtles. We considered that barriers were "high" when small thermal changes had comparatively large effects and "low" when the effects were small...
2017: PloS One
https://www.readbyqxmd.com/read/28543995/the-effects-of-restoring-logged-tropical-forests-on-avian-phylogenetic-and-functional-diversity
#5
Cindy C P Cosset, David P Edwards
Selective logging is the most prevalent land-use change in the tropics. Despite the resulting degradation of forest structure, selectively logged forests still harbour a substantial amount of biodiversity leading to suggestions that their protection is the next best alternative to conserving primary, old-growth forests. Restoring carbon stocks under Reducing Emissions from Deforestation and Forest Degradation (REDD+) schemes is a potential method for obtaining funding to protect logged forests, via enrichment planting and liberation cutting of vines...
May 24, 2017: Ecological Applications: a Publication of the Ecological Society of America
https://www.readbyqxmd.com/read/28543871/tropical-specialist-versus-climate-generalist-diversification-and-demographic-history-of-sister-species-of-carlia%C3%A2-skinks-from-northwestern-australia
#6
Ana C Afonso Silva, Jason G Bragg, Sally Potter, Carlos Fernandes, Maria Manuela Coelho, Craig Moritz
Species endemic to the tropical regions are expected to be vulnerable to future climate change due in part to their relatively narrow climatic niches. In addition, these species are more likely to have responded strongly to past climatic change, and this can be explored through phylogeographic analyses. To test the hypothesis that tropical specialists are more sensitive to climate change than climate generalists, we generated and analyze sequence data from mtDNA and ~2500 exons to compare scales of historical persistence and population fluctuation in two sister species of Australian rainbow skinks: the tropical specialist Carlia johnstonei and the climate generalist C...
May 24, 2017: Molecular Ecology
https://www.readbyqxmd.com/read/28543388/environmental-constraints-on-the-compositional-and-phylogenetic-beta-diversity-of-tropical-forest-snake-assemblages
#7
Mario R Moura, Henrique C Costa, Antônio J S Argôlo, Walter Jetz
The ongoing biodiversity crisis increases the importance and urgency of studies addressing the role of environmental variation on the composition and evolutionary history of species assemblages, but especially the tropics and ectotherms remain understudied. In regions with rainy summers, coexistence of ectothermic species may be determined by the partitioning of the climatic niche, since ectotherms can rely on water availability and thermoregulatory behaviour to buffer constraints along their climatic niche...
May 22, 2017: Journal of Animal Ecology
https://www.readbyqxmd.com/read/28542587/seminal-plasma-induces-inflammation-and-enhances-hiv-1-replication-in-human-cervical-tissue-explants
#8
Andrea Introini, Stéphanie Boström, Frideborg Bradley, Anna Gibbs, Axel Glaessgen, Annelie Tjernlund, Kristina Broliden
The most immediate and evident effect of mucosal exposure to semen in vivo is a local release of proinflammatory mediators accompanied by an influx of leukocytes into the female genital mucosa (FGM). The implication of such response in HIV-1 transmission has never been addressed due to limitations of currently available experimental models. Using human tissue explants from the uterine cervix, we developed a system of mucosal exposure to seminal plasma (SP) that supports HIV-1 replication. Treatment of ectocervical explants with SP resulted in the upregulation of inflammatory and growth factors, including IL-6, TNF, CCL5, CCL20, CXCL1, and CXCL8, and IL1A, CSF2, IL7, PTGS2, as evaluated by measuring protein levels in explant conditioned medium (ECM) and gene expression in tissue...
May 19, 2017: PLoS Pathogens
https://www.readbyqxmd.com/read/28542538/new-evidence-indicates-the-presence-of-barracuda-sphyraenidae-and-supports-a-tropical-marine-environment-in-the-miocene-of-madagascar
#9
Michael D Gottfried, Karen E Samonds, Summer A Ostrowski, Tsiory Harimalala Andrianavalona, Tolotra Niaina Ramihangihajason
Recent exploration of Miocene-age deposits at Nosy Makamby, a small island ~50 km southwest of Mahajanga city in northwestern Madagascar, has led to the recovery of a large sample [82] of isolated barracuda teeth (Sphyraena sp.). in a tropical marine fauna that also includes diverse marine invertebrates, chondrichthyans, bony fishes, turtles, crocodylians, and sirenians. Characteristically for barracudas, the teeth are labiolingually flattened and fang-like with a broadly triangular and blade-like acuminate outline and sharply edged but unserrated cutting margins...
2017: PloS One
https://www.readbyqxmd.com/read/28542427/fine-mapping-and-candidate-gene-analysis-of-qtac8-a-major-quantitative-trait-locus-controlling-tiller-angle-in-rice-oryza-sativa-l
#10
Jiwai He, Gaoneng Shao, Xiangjin Wei, Fenglin Huang, Zhonghua Sheng, Shaoqing Tang, Peisong Hu
Rice tiller angle is an important agronomic trait that contributes to crop production and plays a vital role in high yield breeding. In this study, a recombinant inbred line (RIL) population derived from the cross of a glabrous tropical japonica rice D50 and an indica rice HB277, was used to investigate quantitative trait loci (QTLs) controlling rice tiller angle. Two major QTLs, qTAC8 and qTAC9, were detected. While qTAC9 mapped with a previously identified gene (TAC1), using a BC2F2 population qTAC8 was mapped to a 16...
2017: PloS One
https://www.readbyqxmd.com/read/28542329/novel-agoshrna-molecules-for-silencing-of-the-ccr5-co-receptor-for-hiv-1-infection
#11
Elena Herrera-Carrillo, Ben Berkhout
Allogeneic transplantation of blood stem cells from a CCR5-Δ32 homozygous donor to an HIV-infected individual, the "Berlin patient", led to a cure. Since then there has been a search for approaches that mimic this intervention in a gene therapy setting. RNA interference (RNAi) has evolved as a powerful tool to regulate gene expression in a sequence-specific manner and can be used to inactivate the CCR5 mRNA. Short hairpin RNA (shRNA) molecules can impair CCR5 expression, but these molecules may cause unintended side effects and they will not be processed in cells that lack Dicer, such as monocytes...
2017: PloS One
https://www.readbyqxmd.com/read/28542258/bycatch-in-the-maldivian-pole-and-line-tuna-fishery
#12
Kelsey I Miller, Ibrahim Nadheeh, A Riyaz Jauharee, R Charles Anderson, M Shiham Adam
Tropical tuna fisheries are among the largest worldwide, with some having significant bycatch issues. However, pole-and-line tuna fisheries are widely believed to have low bycatch rates, although these have rarely been quantified. The Maldives has an important pole-and-line fishery, targeting skipjack tuna (Katsuwonus pelamis). In the Maldives, 106 pole-and-line tuna fishing days were observed between August 2014 and November 2015. During 161 fishing events, tuna catches amounted to 147 t: 72% by weight was skipjack, 25% yellowfin tuna (Thunnus albacares) and 3% other tunas...
2017: PloS One
https://www.readbyqxmd.com/read/28542223/measuring-changes-in-transmission-of-neglected-tropical-diseases-malaria-and-enteric-pathogens-from-quantitative-antibody-levels
#13
Benjamin F Arnold, Mark J van der Laan, Alan E Hubbard, Cathy Steel, Joseph Kubofcik, Katy L Hamlin, Delynn M Moss, Thomas B Nutman, Jeffrey W Priest, Patrick J Lammie
BACKGROUND: Serological antibody levels are a sensitive marker of pathogen exposure, and advances in multiplex assays have created enormous potential for large-scale, integrated infectious disease surveillance. Most methods to analyze antibody measurements reduce quantitative antibody levels to seropositive and seronegative groups, but this can be difficult for many pathogens and may provide lower resolution information than quantitative levels. Analysis methods have predominantly maintained a single disease focus, yet integrated surveillance platforms would benefit from methodologies that work across diverse pathogens included in multiplex assays...
May 19, 2017: PLoS Neglected Tropical Diseases
https://www.readbyqxmd.com/read/28542172/ecosystem-sentinels-for-climate-change-evidence-of-wetland-cover-changes-over-the-last-30-years-in-the-tropical-andes
#14
Olivier Dangles, Antoine Rabatel, Martin Kraemer, Gabriel Zeballos, Alvaro Soruco, Dean Jacobsen, Fabien Anthelme
While the impacts of climate change on individual species and communities have been well documented there is little evidence on climate-mediated changes for entire ecosystems. Pristine alpine environments can provide unique insights into natural, physical and ecological response to climate change yet broad scale and long-term studies on these potential 'ecosystem sentinels' are scarce. We addressed this issue by examining cover changes of 1689 high-elevation wetlands (temporarily or perennial water-saturated grounds) in the Bolivian Cordillera Real, a region that has experienced significant warming and glacier melting over the last 30 years...
2017: PloS One
https://www.readbyqxmd.com/read/28542161/land-use-history-and-population-dynamics-of-free-standing-figs-in-a-maturing-forest
#15
Larissa Albrecht, Robert F Stallard, Elisabeth K V Kalko
Figs (Ficus sp.) are often considered as keystone resources which strongly influence tropical forest ecosystems. We used long-term tree-census data to track the population dynamics of two abundant free-standing fig species, Ficus insipida and F. yoponensis, on Barro Colorado Island (BCI), a 15.6-km2 island in Lake Gatún, Panama. Vegetation cover on BCI consists of a mosaic of old growth (>400 years) and maturing (about 90-150 year old) secondary rainforest. Locations and conditions of fig trees have been mapped and monitored on BCI for more than 35 years (1973-2011), with a focus on the Lutz Catchment area (25 ha)...
2017: PloS One
https://www.readbyqxmd.com/read/28541934/evaluation-of-ageratum-conyzoides-in-field-scale-constructed-wetlands-cws-for-domestic-wastewater-treatment
#16
A S Tilak, Suhas P Wani, A Datta, M D Patil, M Kaushal, K R Reddy
Ageratum conyzoides were evaluated in field scale subsurface flow constructed wetlands (CWs) to quantify its nitrogen (N) and phosphorus (P) uptake and compare with wetland plants (Pistia stratiotes, Typha latifolia and Canna indica). The two-field scale subsurface flow CWs, located in the International Crops Research Institute for Semi-Arid Tropics, received wastewater from an urban colony. The CW1 and CW2 had the same dimensions (length:10 m, width:3 m, total depth:1.5 m and sand and gravel:1 m), similar flow rates (3 m(3)/d), hydraulic loading rates (HLRs-10 cm/d) and hydraulic retention time (HRT-5 days) from July 2014-August 2015...
May 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28541931/the-role-of-constructed-wetlands-for-biomass-production-within-the-water-soil-waste-nexus
#17
C T Avellan, R Ardakanian, P Gremillion
The use of constructed wetlands for water pollution control has a long standing tradition in urban, peri-urban, rural, agricultural and mining environments. The capacity of wetland plants to take up nutrients and to filter organic matter has been widely discussed and presented in diverse fora and published in hundreds of articles. In an ever increasingly complex global world, constructed wetlands not only play a role in providing safe sanitation in decentralized settings, shelter for biodiversity, and cleansing of polluted sites, in addition, they produce biomass that can be harvested and used for the production of fodder and fuel...
May 2017: Water Science and Technology: a Journal of the International Association on Water Pollution Research
https://www.readbyqxmd.com/read/28541570/evolutionary-trade-offs-between-drought-resistance-mechanisms-across-a-precipitation-gradient-in-a-seasonally-dry-tropical-oak-quercus-oleoides
#18
Jose A Ramírez-Valiente, Jeannine Cavender-Bares
No abstract text is available yet for this article.
May 24, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28541561/effects-of-rainfall-exclusion-on-leaf-gas-exchange-traits-and-osmotic-adjustment-in-mature-canopy-trees-of-dryobalanops-aromatica-dipterocarpaceae-in-a-malaysian-tropical-rain-forest
#19
Yuta Inoue, Tomoaki Ichie, Tanaka Kenzo, Aogu Yoneyama, Tomo'omi Kumagai, Tohru Nakashizuka
Climate change exposes vegetation to unusual levels of drought, risking a decline in productivity and an increase in mortality. It still remains unclear how trees and forests respond to such unusual drought, particularly Southeast Asian tropical rain forests. To understand leaf ecophysiological responses of tropical rain forest trees to soil drying, a rainfall exclusion experiment was conducted on mature canopy trees of Dryobalanops aromatica Gaertn.f. (Dipterocarpaceae) for 4 months in an aseasonal tropical rain forest in Sarawak, Malaysia...
May 24, 2017: Tree Physiology
https://www.readbyqxmd.com/read/28541458/microbiome-analysis-of-a-disease-affecting-the-deep-sea-sponge-geodia-barretti
#20
Heidi M Luter, Raymond J Bannister, Steve Whalan, Tina Kutti, Mari-Carmen Pineda, Nicole S Webster
Reports of sponge disease are becoming increasingly frequent, although almost all instances involve shallow-water, tropical species. Here, we describe the first disease affecting the deep-water sponge, Geodia barretti. The disease is characterised by brown/black discolouration of the sponge tissue, extensive levels of tissue disintegration and increased levels of fouling. Disease prevalence was quantified using video survey transects conducted between 100 and 220 meters in Korsfjorden, Norway and the microbial communities of healthy and diseased sponges were compared using 16S rRNA gene sequencing...
May 24, 2017: FEMS Microbiology Ecology
keyword
keyword
56633
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"