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sterile pyuria

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https://www.readbyqxmd.com/read/29780147/disseminated-mycobacterium-avium-infection-presenting-with-bladder-lesions-in-a-patient-with-interferon-%C3%AE-neutralizing-autoantibodies
#1
Koichi Miyashita, Shun Matsuura, Kenichi Tajima, Shogo Tajima, Ami Aoki, Takuro Sakagami, Naoki Koshimizu, Mikio Toyoshima, Takafumi Suda
A 63-year-old woman presented with a fever, eruption, and sterile pyuria. A cystoscopic examination revealed submucosal nodular lesions in the trigone of the bladder, and a biopsy specimen showed epithelioid cell granulomas in the lamina propria of the bladder. Mycobacterium avium grew in the urine culture. Other organ involvement, such as the lungs, spleen, bones, muscles, and pelvic lymph nodes, was observed on radiological examinations, and M. avium was isolated from some organ lesions. Interferon-γ-neutralizing autoantibodies were detected in the patient' s serum...
May 18, 2018: Internal Medicine
https://www.readbyqxmd.com/read/29563943/discrimination-of-kawasaki-disease-with-concomitant-adenoviral-detection-differentiating-from-isolated-adenoviral-infection
#2
Jong Han Kim, Hye Ree Kang, Su Yeong Kim, Ji-Eun Ban
Purpose: Human adenovirus infection mimics Kawasaki disease (KD) but can be detected in KD patients. The aim of this study was to determine the clinical differences between KD with adenovirus infection and only adenoviral infection and to identify biomarkers for prediction of adenovirus-positive KD from isolated adenoviral infection. Methods: A total of 147 patients with isolated adenovirus were identified by quantitative polymerase chain reaction. In addition, 11 patients having KD with adenovirus, who were treated with intravenous immunoglobulin therapy during the acute phase of KD were also evaluated...
February 2018: Korean Journal of Pediatrics
https://www.readbyqxmd.com/read/29560055/high-prevalence-of-sterile-pyuria-in-the-setting-of-sexually-transmitted-infection-in-women-presenting-to-an-emergency-department
#3
Stacia B Shipman, Chelsea R Risinger, Crystalle M Evans, Chelsey D Gilbertson, David E Hogan
Introduction: The clinical presentations for sexually transmitted infections (STI) and urinary tract infections (UTI) often overlap, and symptoms of dysuria and urinary frequency/urgency occur with both STIs and UTIs. Abnormal urinalysis (UA) findings and pyuria are common in both UTIs and STIs, and confirmatory urine cultures are not available to emergency clinicians to aid in decision-making regarding prescribing antibiotics for UTIs. The objective of this study was to determine the frequency of sterile pyuria in women with confirmed STIs, as well as whether the absolute number of leukocytes on microscopy or nitrite on urine dipstick correlated with positive urine cultures in patients with confirmed STIs...
March 2018: Western Journal of Emergency Medicine
https://www.readbyqxmd.com/read/29450211/-actinotignum-schaalii-infection-a-clandestine-cause-of-sterile-pyuria
#4
Lucy E Horton, Sanjay R Mehta, Lejla Aganovic, Joshua Fierer
Actinotignum schaalii is an underappreciated cause of urinary tract infections (UTIs) in older adults. The diagnosis may be missed due to difficulty isolating and identifying the organism. Complications can result because the organism is intrinsically resistant to 2 commonly used drugs to treat UTI, as illustrated by this case.
February 2018: Open Forum Infectious Diseases
https://www.readbyqxmd.com/read/29063893/a-case-of-sterile-pyuria-caused-by-chlamydia-trachomatis-and-mycoplasma-hominis-a-diagnostic-challenge
#5
Agrima Mian, Sujeesh Sebastian, Nazneen Arif, Manish Soneja, Benu Dhawan
Sterile pyuria is a highly prevalent condition with a wide aetiological spectrum, which often challenges the diagnostician. We describe the case of a middle-aged female admitted to the medical Intensive Care Unit for acute gastroenteritis, whose urinalysis revealed persistent sterile pyuria. Polymerase chain reaction assay in urine was positive for Chlamydia trachomatis and Mycoplasma hominis. She responded to antimicrobial therapy. We hereby reflect on the approach to a case of sterile pyuria and review the available literature on this entity...
July 2017: Indian Journal of Medical Microbiology
https://www.readbyqxmd.com/read/28798240/tetraparesia-an-unusual-presentation-of-disseminated-tuberculosis
#6
Filipa Quaresma, Margarida Bentes Jesus
A 48-year-old man with a 4 months history of asthenia, anorexia, 10 kg weight loss and 1 month of hematuria and dysuria was admitted to another hospital for sudden muscular weakness. He was found to have areflexic tetraparesis and was referred to our hospital.On admission, he was bradycardic, tachypneic, with flaccid tetraplegia. Laboratory results showed metabolic acidemia, severe hyperkalemia and hyponatremia, acute renal dysfunction and sterile pyuria. After hyperkalemia correction, the neurological symptoms resolved...
August 10, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28735999/results-of-real-time-multiplex-polymerase-chain-reaction-assay-in-renal-transplant-recipients-with-sterile-pyuria
#7
M Sarier, M Demir, S Goktas, I Duman, M Buyukkinaci, Y Yuksel, S Tekin, A H Yavuz, A Sengul
Urinary tract infections are a major cause of morbidity and hospitalization after renal transplantation. Patients treated with immunosuppressive drugs suffer not only from common uropathogens but also from opportunistic infections caused by unusual uropathogens. Sterile pyuria is associated with numerous infectious agents including viruses, fungi, and atypical or fastidious organisms. The objective of this study was to investigate the pathogens using real-time multiplex polymerase chain reaction (rtMPCR) assay in sterile pyuria of renal transplant recipients...
July 2017: Transplantation Proceedings
https://www.readbyqxmd.com/read/28721513/does-pyuria-always-suggest-urinary-tract-infection-with-common-microorganisms-questions
#8
Mehmet Taşdemir, Hüseyin Kaya, Zeynep Atam Taşdemir
Genitourinary system tuberculosis (GUTB) is a chronic granulomatous infection in which tuberculous bacilli affect one or more organs in the genitourinary system. In this report, an unusual presentation of miliary tuberculosis was presented as GUTB. A 15-year-old girl presented with complaints of severe abdominal pain and dysuria. Abdominal examination showed tenderness and defense. Pyuria and microscopic hematuria were observed. Acute abdominal causes could not be excluded through abdominal ultrasound. On abdominal computed tomography, a necrotic lesion was detected in the right kidney...
April 2018: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28631909/-characterization-of-microbial-flora-in-patients-suspected-of-having-urogenital-tuberculosis
#9
A G Cherednichenko, E V Kulchavenya
INTRODUCTION: In the structure of tuberculosis morbidity, urogenital tuberculosis (UGT) ranks second or third only to pulmonary tuberculosis. Every fourth patient has the stage of cavern formation at first presentation. Seventy five percent of nephrotuberculosis cases co-occur with nonspecific pyelonephritis, which excludes "sterile pyuria". We aimed to determine the microbial spectrum of urine and gonadal appendages in patients with suspected UGT and to investigate the susceptibility of the isolated microorganisms to the main antibacterial drugs...
June 2017: Urologii︠a︡
https://www.readbyqxmd.com/read/28465804/atypical-desquamation-in-a-2-5-year-old-boy-with-kawasaki-disease-a-case-report
#10
Ali Adib, Ali Fazel, Seyed Hesamedin Nabavizadeh, Sohaila Alyasin, Sara Kashef
Kawasaki disease (KD) is a vasculitis that mostly affects children under 5 years of age. This article presents a 2.5-year-old boy who presented with 6 days of fever, generalized maculopapular rash, bilateral non-exudative conjunctivitis, cracked lips, right cervical lymphadenopathy, erythematous extremities, and perianal desquamation. Laboratory studies showed leukocytosis and sterile pyuria. Because diagnosis of KD was proved, oral acetylsalicylic acid with the anti-inflammatory dose and intravenous immunoglobulin were started for him...
February 2017: Electronic Physician
https://www.readbyqxmd.com/read/28435765/chronic-nephropathy-from-dietary-hyperoxaluria-sustained-improvement-of-renal-function-after-dietary-intervention
#11
Yijuan Sun, Bruce L Horowitz, Karen S Servilla, Joanna R Fair, Darlene Vigil, Kavitha Ganta, Larry Massie, Antonios H Tzamaloukas
A 56-year-old man with stable chronic kidney disease (CKD) for two years following a single episode of calcium oxalate urolithiasis developed progressive elevation of his serum creatinine concentration. Urinalysis revealed pyuria and white cell casts, a few red blood cells, minimal proteinuria, and no crystals. Urine culture was sterile. Gallium scintigraphy was consistent with interstitial nephritis. Proton pump inhibitor intake was discontinued, and a short course of oral corticosteroids was initiated. Percutaneous kidney biopsy, performed because of the continued deterioration of renal function to a minimum estimated glomerular filtration rate (eGFR) value of 15 mL/min per 1...
March 20, 2017: Curēus
https://www.readbyqxmd.com/read/28390079/pitfalls-of-diagnosing-urinary-tract-infection-in-infants-and-young-children
#12
Yasuhito Yamasaki, Osamu Uemura, Takuhito Nagai, Satoshi Yamakawa, Yoshiko Hibi, Masaki Yamamoto, Masaru Nakano, Katsuaki Kasahara, Zhang Bo
BACKGROUND: The aim of this study was to examine the sensitivity and specificity of pyuria-based diagnosis of urinary tract infection (UTI) in urine collected by transurethral catheterization, and the reliability of diagnosis of pyuria in urine collected in a perineal bag. The gold standard for UTI diagnosis is significant colony counts of a single organism in urine obtained in a sterile manner. METHODS: We enrolled 301 patients who underwent medical examination at the present hospital for possible UTI between January 2005 and December 2009...
July 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
https://www.readbyqxmd.com/read/28348604/urinary-lactate-dehydrogenase-activity-and-its-isozyme-patterns-in-kawasaki-disease
#13
Yoichi Kawamura, Seiichiro Takeshita, Takashi Kanai, Mari Takizawa, Yusuke Yoshida, Yuki Tsujita, Shigeaki Nonoyama
Abnormal urinary findings, such as sterile pyuria, proteinuria, and microscopic hematuria, are often seen in the acute phase of Kawasaki disease (KD). We investigated the potential significance of urinary lactate dehydrogenase (U-LDH) activity and its isozyme patterns in KD. Total U-LDH activity and its isozymes (U-LDH1-5) levels were compared among 120 patients with KD, 18 patients with viral infection (VI), and 43 patients with upper urinary tract infection (UTI) and additionally compared between intravenous immunoglobulin (IVIG) responders (n = 89) and nonresponders (n = 31) with KD...
2017: International Journal of Pediatrics
https://www.readbyqxmd.com/read/28216941/isolated-urachal-malakoplakia-mimicking-malignancy
#14
Saisriharsha Pakalapati, Sanjay Parachuri, Venkateshwara Rao Kakarla, Mahesh Babu Byrappa
Malakoplakia is an unusual inflammatory disease with uncertain pathogenesis affecting any organ in the body, but predominantly genitourinary tract, with specific predilection to the bladder. We report a rare case of isolated malakoplakia of the urachus in a 29-year-old male patient who presented with lower urinary tract symptoms without any hematuria. Investigations revealed sterile pyuria with no bacterial growth in urine. Radiological investigations revealed a mass in the urachal region. The patient underwent cystoscopy with biopsy followed by pelvic lymph node dissection and partial cystectomy with excision of the urachal mass...
January 2017: Urology Annals
https://www.readbyqxmd.com/read/28087922/urogenital-tuberculosis
#15
REVIEW
André A Figueiredo, Antônio M Lucon, Miguel Srougi
Urogenital tuberculosis is the second most frequent form of extrapulmonary tuberculosis. Starting with a pulmonary focus, 2 to 20% of patients develop urogenital tuberculosis through hematogenous spread to the kidneys, prostate, and epididymis; through the descending collecting system to the ureters, bladder, and urethra; and through the ejaculatory ducts to the genital organs. Urogenital tuberculosis occurs at all age ranges, but it is predominant in males in their fourth and fifth decades. It is a serious, insidious disease, generally developing symptoms only at a late stage, which leads to a diagnostic delay with consequent urogenital organ destruction; there are reports of patients with renal failure as their initial clinical presentation...
January 2017: Microbiology Spectrum
https://www.readbyqxmd.com/read/27865246/renal-tuberculosis-presenting-as-acute-pyelonephritis-a-rarity
#16
Ajay Kumar Verma, Ashwini Kumar Mishra, Manoj Kumar, Surya Kant, Anubhuti Singh, Ajay Singh
One of the major health problems faced particularly by the developing world since ages is that of tuberculosis (TB). Genito-urinary tuberculosis (GUTB) is the second most common extrapulmonary TB, with kidney being the most frequent site of infection. Due to the diverse and atypical clinical manifestations of urinary TB, the disease is easy to misdiagnose. The diagnosis of renal TB should be suspected in a nonspecific bacterial cystitis associated with a therapeutic failure or a sterile pyuria and a past history of pulmonary TB with important radiologic findings, particularly with the help of CT scan...
July 2016: Indian Journal of Tuberculosis
https://www.readbyqxmd.com/read/27790302/urinary-mycobacterium-avium-presenting-as-sterile-pyuria
#17
Kai Yang, Mary Samplaski, Tony Mazzulli, Kirk Lo, Ethan Grober, Keith Allen Jarvi
A 65-year-old healthy woman presented with persistent, asymptomatic sterile pyuria detected by her family physician. While she did not have symptoms, the patient recounts that she has had cloudy urine for years. Cultures of the urine for bacteria showed no growth and no fungi were identified. First-morning urine samples were sent for both tuberculosis and nontuberculosis mycobacterium species testing. The culture grew genotypically identified Mycobaterium avium complex (MAC). Mantoux skin testing was positive...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
https://www.readbyqxmd.com/read/27492273/proton-pump-inhibitors-are-not-associated-with-acute-kidney-injury-in-critical-illness
#18
Joon Lee, Roger G Mark, Leo Anthony Celi, John Danziger
Recent epidemiologic data linking proton pump inhibitor (PPI) use to acute and chronic kidney dysfunction is yet to be validated in other populations, and mechanisms have not been explored. Using a large, well phenotyped inception cohort of 15 063 critically ill patients, we examined the risk of acute kidney injury (AKI), as defined by the Kidney Disease Improving Global Outcomes criteria guidelines, according to prior use of a PPI, histamine-2 receptor antagonist (H2 RA), or neither. A total of 3725 (24...
December 2016: Journal of Clinical Pharmacology
https://www.readbyqxmd.com/read/26917663/sterile-pyuria-a-practical-management-guide
#19
Peter Glen, Akash Prashar, Amr Hawary
No abstract text is available yet for this article.
March 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
https://www.readbyqxmd.com/read/26910613/the-effectiveness-of-prophylactic-antibiotics-with-oral-levofloxacin-against-post-shock-wave-lithotripsy-infectious-complications-a-randomized-controlled-trial
#20
RANDOMIZED CONTROLLED TRIAL
Cheng-Hsing Hsieh, Stephen Shei-Dei Yang, Shang-Jen Chang
OBJECTIVE: To evaluate the efficacy of prophylactic antibiotics in reduction of infections after shock wave lithotripsy (SWL) in patients undergoing shock wave lithotripsy (SWL). METHODS: The study was a randomized control trial. Between 2012 and 2014, patients with pre-operative sterile urine undergoing SWL were randomly assigned by the randomization ratio of 1:1 to receive prophylactic antibiotics with single-dose oral levofloxacin (500 mg) or no treatment (control group), respectively...
June 2016: Surgical Infections
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