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sterile pyuria

Joon Lee, Roger G Mark, Leo Anthony Celi, John Danziger
Recent epidemiologic data linking proton pump inhibitor (PPI) use to acute and chronic kidney dysfunction is yet to be validated in other populations, and mechanisms have not been explored. Using a large, well phenotyped inception cohort of 15,063 critically ill patients, we examined the risk of acute kidney injury (AKI), as defined by the Kidney Disease Improving Global Outcomes criteria guidelines, according to prior use of a PPI, histamine-2 receptor antagonist (H2 RA), or neither. A total of 3,725(24.7%) patients reported PPI use prior to admission, while 905(6...
August 5, 2016: Journal of Clinical Pharmacology
Peter Glen, Akash Prashar, Amr Hawary
No abstract text is available yet for this article.
March 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Cheng-Hsing Hsieh, Stephen Shei-Dei Yang, Shang-Jen Chang
OBJECTIVE: To evaluate the efficacy of prophylactic antibiotics in reduction of infections after shock wave lithotripsy (SWL) in patients undergoing shock wave lithotripsy (SWL). METHODS: The study was a randomized control trial. Between 2012 and 2014, patients with pre-operative sterile urine undergoing SWL were randomly assigned by the randomization ratio of 1:1 to receive prophylactic antibiotics with single-dose oral levofloxacin (500 mg) or no treatment (control group), respectively...
June 2016: Surgical Infections
Lisa C Goldberg, Jessica Prior, Dale Woolridge
BACKGROUND: Appendicitis is uncommon in children <6 months old, with few observational studies reporting cases of children younger than 5 years old with the diagnosis. The classic periumbilical pain that migrates to the right lower quadrant, followed by the onset of fever and vomiting, is present in approximately 40% of pediatric patients under 12 years of age with appendicitis. CASE REPORT: A 4-month-old girl presented to the Emergency Department (ED) with acute onset of grunting, pallor, fussiness, emesis, and diarrhea...
May 2016: Journal of Emergency Medicine
Murat Muhtar Yılmazer, Taliha Öner, Selman Gökalp, Önder Doksöz, Barış Güven, Özgür Vupa-Çilengiroğlu, Timur Meşe, Vedide Tavlı
The aim of this study was to identify the risk factors for persistence of coronary artery abnormalities (CAAs) in Kawasaki disease and to compare the differences between complete (n=25) and incomplete (n=18) forms of the disease in relation to CAAs. The patients' demographic (age and sex), clinical (season of admission, duration of fever, form of Kawasaki disease), laboratory (complete blood count, eosinophil count, serum biochemistry, C-reactive protein level, erythrocyte sedimentation rate [ESR], urinary analysis), echocardiographic and therapeutic data were evaluated retrospectively from the medical records...
May 2015: Turkish Journal of Pediatrics
Mehmet Riza Altiparmak, Sinan Trabulus, Ilker Inanc Balkan, Serkan Feyyaz Yalin, Nazim Denizli, Gonul Aslan, Hasan Erdal Doruk, Aynur Engin, Recep Tekin, Serhat Birengel, Birsen Durmaz Cetin, Ferhat Arslan, Vedat Turhan, Ali Mert
We aimed to investigate the demographic, clinical, diagnostic, treatment and outcome features of patients with urinary tuberculosis (UTB). Patients with UTB admitted to seven separate centers across Turkey between 1995 and 2013 were retrospectively evaluated. The diagnosis of UTB was made by the presence of any clinical finding plus positivity of one of the following: (1) acid-fast bacilli (AFB) in urine, (2) isolation of Mycobacterium tuberculosis, (3) polymerase chain reaction (PCR) for M. tuberculosis, (4) histopathological evidence for TB...
August 2015: Renal Failure
Anoush Azarfar, Yalda Ravanshad, Sepideh Bagheri, Mohammad Esmaeeli, Mahmood Malek Nejad
OBJECTIVE: The purpose of this study is to evaluate the clinical presentation, laboratory findings, and response to treatment in girls with labial adhesion younger than 23 months. MATERIAL AND METHODS: A retrospective chart review of all girls younger than 23 months with the diagnosis of labial adhesion was referred to Dr Sheikh children's clinic in Mashhad in northeast Iran between 1998 and 2013. RESULTS: Sixty-three patients were diagnosed with labial adhesion during the review period...
2015: Journal of the Turkish German Gynecological Association
Mohammad I Issack, Dan Jinerdeb
No abstract text is available yet for this article.
June 11, 2015: New England Journal of Medicine
David B Nelson, F Gary Cunningham, Marshall D Lindheimer
No abstract text is available yet for this article.
June 11, 2015: New England Journal of Medicine
Gilbert J Wise, Peter N Schlegel
New England Journal of Medicine, Volume 372, Issue 24, Page 2372-2373, June 2015.
June 11, 2015: New England Journal of Medicine
Toru Watanabe
Kawasaki disease (KD) is an acute, febrile vasculitis that predominantly develops in children ≤ 5 years of age and can lead to multiple organ injuries including the kidneys. Of these injuries, pyuria is a common feature of patients with KD, occurring in 30%-80% of patients. Sterile pyuria is most common in KD patients ≤ 1 year of age. KD patients with sterile pyuria exhibit more severe inflammatory reactions and may have sub-clinical renal injuries. Sterile pyuria in KD is associated with mononuclear cells (not neutrophils) in the urine...
May 8, 2015: World Journal of Clinical Pediatrics
Gilbert J Wise, Peter N Schlegel
New England Journal of Medicine, Volume 372, Issue 11, Page 1048-1054, March 2015.
March 12, 2015: New England Journal of Medicine
S D Sule, D G Moodalbail, J Burnham, B Fivush, S L Furth
INTRODUCTION: Children with systemic lupus erythematosus (SLE) have an increased prevalence of kidney disease compared to their adult counterparts. Our goal was to identify potential clinical and laboratory predictors of renal disease. METHODS: We performed a cohort study of incident and prevalent patients with SLE aged ≤19 years. Retrospective data from initial presentation until study enrollment was also collected. Laboratory and clinic data were recorded from each clinic visit including disease activity indices, autoantibodies, urinalyses, blood counts, and metabolic profile...
July 2015: Lupus
Jonathan Y C Ding, Dominique Ibañez, Dafna D Gladman, Murray B Urowitz
OBJECTIVE: To identify patients presenting with isolated hematuria and/or pyuria in the absence of other systemic lupus erythematosus (SLE) disease activity, describe their demographics, and determine whether they present with evidence of SLE flare in a period adjacent to the presentation. METHODS: We studied patients followed at the University of Toronto Lupus Clinic between 1970 and 2012. An episode of isolated hematuria (> 5 red blood cells per high power field) and/or pyuria (> 5 white blood cells per high power field) was defined as 2 consecutive visits with these findings in the absence of other concurrent SLE manifestations such as proteinuria, casts, or azotemia...
March 2015: Journal of Rheumatology
Mohamed Alkhatim Alsammani, Mohamed Issa Ahmed, Nahla Farouk Abdelatif
BACKGROUND: Childhood urinary infections are among the most common febrile illnesses occurring during this period with varying susceptibility to antibiotic. AIM: The aim of this study was to identify uropathogens responsible to for urinarytract infection (UTIs) in children less than 5 years of age, and determine the antibiograms of the isolates to commonly used antibiotics. PATIENTS AND METHODS: Hundred and four children (2 months - 5 years old) seen at the Gadarif Teaching Hospital from January 2012 and December 2013 were evaluated...
August 2014: Medical Archives
Satoshi Kutsuna, Yasuyuki Kato, Nobuo Koizumi, Kei Yamamoto, Yoshihiro Fujiya, Momoko Mawatari, Nozomi Takeshita, Kayoko Hayakawa, Shuzo Kanagawa, Norio Ohmagari
Leptospirosis is one of the most common travel-related infections. We report 5 cases of travel-related leptospirosis who presented at our clinic between January 2008 and December 2013. Patients were included in the study if they presented with a clinical profile that was compatible with the disease within 21 days of their return from traveling, which were laboratory-diagnosed as leptospirosis by blood culture, rise in antibody titers in paired sera using the microscopic agglutination test (MAT), and/or DNA detection using flaB-nested PCR...
March 2015: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
Tumay Ipekci, Derya Seyman, Hande Berk, Orcun Celik
Urinary tract infections (UTIs) caused by extended-spectrum beta-lactamase (ESBL)-producing bacteria have become a growing problem limiting therapeutic options. The aim of this study was to investigate the clinical and microbiological efficacy of amikacin treatment in adult patients with lower UTIs due to ESBL-producing Escherichia coli (Ec) or Klebsiella pneumonia (Kp). We conducted a retrospective study of 36 outpatients aged >18 years with dysuria or problems with frequency or urgency in passing urine; pyuria and a positive urine culture (10(5) cfu/ml) for ESBL producing Ec or Kp which is also resistant to nitrofurantoin, fosfomycin, quinolones and trimethoprim/sulfamethoxazole, between January 2013 and February 2014...
December 2014: Journal of Infection and Chemotherapy: Official Journal of the Japan Society of Chemotherapy
Seher Çetinkaya Altuntaş, Tümay Ipekçi, Gülşen Yakupoğlu, Nuray Erin
Urinary tract infections (UTI) are important health problems and predisposing causes of UTI are not entirely known. Neuro-immune interactions play an important role in human health and disease. Capsaicin-sensitive sensory nerves which in nerve bladder extensively regulate immune system through neuropeptides such as substance P (SP), calcitonin-gene related peptide (CGRP) and vasoactive intestinal peptide (VIP). In addition these neuropeptides also have anti-bacterial effects. To determine how the levels of these peptides changes during UTI, 67 patients (50-90 years-old) diagnosed with UTI in Akdeniz University Faculty of Medicine Hospital were compared with 37 healthy people 50 years or older as the control group...
June 2014: Peptides
Huma Mamun Mahmud, Sobia Qureshi, Darshan Kumar, Syed Farman
OBJECTIVES: (1) To determine frequency of urinary tract infection among pyuric diabetic patients. (2) To determine sterile pyuria frequency among pyuric diabetic patients. (3) To determine factors predisposing to urinary tract infection. METHODS: This is a non randomized, prospective observational study done in tertiary care set up of Dow University of Health Sciences, Karachi. Data collection done from June 2013 till August 2013. Sampling was done by convenient method, sample size of 97...
January 2014: Pakistan Journal of Medical Sciences Quarterly
Linda Berney-Meyer, Noelyn Hung, Tania Slatter, John Bw Schollum, A Richard Kitching, Robert J Walker
BACKGROUND: Omeprazole is an important cause of drug-induced acute interstitial nephritis (AIN). How omeprazole induces injury is unknown. METHODS AND RESULTS: Detailed clinical assessment of 25 biopsy-proven cases of omeprazole-induced AIN showed that all patients presented with impaired renal function, sterile pyuria with varying amounts of proteinuria but no eosinophiluria and no systemic symptoms to suggest a vasculitis. Histological analyses were characteristic of an acute tubulitis with an inflammatory cellular infiltrate...
June 2014: Nephrology
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