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sterile pyuria

Yijuan Sun, Bruce L Horowitz, Karen S Servilla, Joanna R Fair, Darlene Vigil, Kavitha Ganta, Larry Massie, Antonios H Tzamaloukas
A 56-year-old man with stable chronic kidney disease (CKD) for two years following a single episode of calcium oxalate urolithiasis developed progressive elevation of his serum creatinine concentration. Urinalysis revealed pyuria and white cell casts, a few red blood cells, minimal proteinuria, and no crystals. Urine culture was sterile. Gallium scintigraphy was consistent with interstitial nephritis. Proton pump inhibitor intake was discontinued, and a short course of oral corticosteroids was initiated. Percutaneous kidney biopsy, performed because of the continued deterioration of renal function to a minimum estimated glomerular filtration rate (eGFR) value of 15 mL/min per 1...
March 20, 2017: Curēus
Yasuhito Yamasaki, Osamu Uemura, Takuhito Nagai, Satoshi Yamakawa, Yoshiko Hibi, Masaki Yamamoto, Masaru Nakano, Katsuaki Kasahara, Zhang Bo
BACKGROUND: The objective of this study was to examine the sensitivity and specificity of pyuria-based diagnosis of urinary tract infection (UTI) in urine collected by transurethral catheterization, and the reliability of diagnosis of pyuria in urine collected in a perineal bag. The gold standard for UTI diagnosis was the presence of significant colony counts of a single organism in urine obtained in a sterile manner. METHODS: We enrolled 301 patients who underwent medical examination in our hospital for possible UTI between January 2005 and December 2009...
April 8, 2017: Pediatrics International: Official Journal of the Japan Pediatric Society
Yoichi Kawamura, Seiichiro Takeshita, Takashi Kanai, Mari Takizawa, Yusuke Yoshida, Yuki Tsujita, Shigeaki Nonoyama
Abnormal urinary findings, such as sterile pyuria, proteinuria, and microscopic hematuria, are often seen in the acute phase of Kawasaki disease (KD). We investigated the potential significance of urinary lactate dehydrogenase (U-LDH) activity and its isozyme patterns in KD. Total U-LDH activity and its isozymes (U-LDH1-5) levels were compared among 120 patients with KD, 18 patients with viral infection (VI), and 43 patients with upper urinary tract infection (UTI) and additionally compared between intravenous immunoglobulin (IVIG) responders (n = 89) and nonresponders (n = 31) with KD...
2017: International Journal of Pediatrics
Saisriharsha Pakalapati, Sanjay Parachuri, Venkateshwara Rao Kakarla, Mahesh Babu Byrappa
Malakoplakia is an unusual inflammatory disease with uncertain pathogenesis affecting any organ in the body, but predominantly genitourinary tract, with specific predilection to the bladder. We report a rare case of isolated malakoplakia of the urachus in a 29-year-old male patient who presented with lower urinary tract symptoms without any hematuria. Investigations revealed sterile pyuria with no bacterial growth in urine. Radiological investigations revealed a mass in the urachal region. The patient underwent cystoscopy with biopsy followed by pelvic lymph node dissection and partial cystectomy with excision of the urachal mass...
January 2017: Urology Annals
André A Figueiredo, Antônio M Lucon, Miguel Srougi
Urogenital tuberculosis is the second most frequent form of extrapulmonary tuberculosis. Starting with a pulmonary focus, 2 to 20% of patients develop urogenital tuberculosis through hematogenous spread to the kidneys, prostate, and epididymis; through the descending collecting system to the ureters, bladder, and urethra; and through the ejaculatory ducts to the genital organs. Urogenital tuberculosis occurs at all age ranges, but it is predominant in males in their fourth and fifth decades. It is a serious, insidious disease, generally developing symptoms only at a late stage, which leads to a diagnostic delay with consequent urogenital organ destruction; there are reports of patients with renal failure as their initial clinical presentation...
January 2017: Microbiology Spectrum
Ajay Kumar Verma, Ashwini Kumar Mishra, Manoj Kumar, Surya Kant, Anubhuti Singh, Ajay Singh
One of the major health problems faced particularly by the developing world since ages is that of tuberculosis (TB). Genito-urinary tuberculosis (GUTB) is the second most common extrapulmonary TB, with kidney being the most frequent site of infection. Due to the diverse and atypical clinical manifestations of urinary TB, the disease is easy to misdiagnose. The diagnosis of renal TB should be suspected in a nonspecific bacterial cystitis associated with a therapeutic failure or a sterile pyuria and a past history of pulmonary TB with important radiologic findings, particularly with the help of CT scan...
July 2016: Indian Journal of Tuberculosis
Kai Yang, Mary Samplaski, Tony Mazzulli, Kirk Lo, Ethan Grober, Keith Allen Jarvi
A 65-year-old healthy woman presented with persistent, asymptomatic sterile pyuria detected by her family physician. While she did not have symptoms, the patient recounts that she has had cloudy urine for years. Cultures of the urine for bacteria showed no growth and no fungi were identified. First-morning urine samples were sent for both tuberculosis and nontuberculosis mycobacterium species testing. The culture grew genotypically identified Mycobaterium avium complex (MAC). Mantoux skin testing was positive...
May 2016: Canadian Urological Association Journal, Journal de L'Association des Urologues du Canada
Joon Lee, Roger G Mark, Leo Anthony Celi, John Danziger
Recent epidemiologic data linking proton pump inhibitor (PPI) use to acute and chronic kidney dysfunction is yet to be validated in other populations, and mechanisms have not been explored. Using a large, well phenotyped inception cohort of 15 063 critically ill patients, we examined the risk of acute kidney injury (AKI), as defined by the Kidney Disease Improving Global Outcomes criteria guidelines, according to prior use of a PPI, histamine-2 receptor antagonist (H2 RA), or neither. A total of 3725 (24...
December 2016: Journal of Clinical Pharmacology
Peter Glen, Akash Prashar, Amr Hawary
No abstract text is available yet for this article.
March 2016: British Journal of General Practice: the Journal of the Royal College of General Practitioners
Cheng-Hsing Hsieh, Stephen Shei-Dei Yang, Shang-Jen Chang
OBJECTIVE: To evaluate the efficacy of prophylactic antibiotics in reduction of infections after shock wave lithotripsy (SWL) in patients undergoing shock wave lithotripsy (SWL). METHODS: The study was a randomized control trial. Between 2012 and 2014, patients with pre-operative sterile urine undergoing SWL were randomly assigned by the randomization ratio of 1:1 to receive prophylactic antibiotics with single-dose oral levofloxacin (500 mg) or no treatment (control group), respectively...
June 2016: Surgical Infections
Lisa C Goldberg, Jessica Prior, Dale Woolridge
BACKGROUND: Appendicitis is uncommon in children <6 months old, with few observational studies reporting cases of children younger than 5 years old with the diagnosis. The classic periumbilical pain that migrates to the right lower quadrant, followed by the onset of fever and vomiting, is present in approximately 40% of pediatric patients under 12 years of age with appendicitis. CASE REPORT: A 4-month-old girl presented to the Emergency Department (ED) with acute onset of grunting, pallor, fussiness, emesis, and diarrhea...
May 2016: Journal of Emergency Medicine
Murat Muhtar Yılmazer, Taliha Öner, Selman Gökalp, Önder Doksöz, Barış Güven, Özgür Vupa-Çilengiroğlu, Timur Meşe, Vedide Tavlı
The aim of this study was to identify the risk factors for persistence of coronary artery abnormalities (CAAs) in Kawasaki disease and to compare the differences between complete (n=25) and incomplete (n=18) forms of the disease in relation to CAAs. The patients' demographic (age and sex), clinical (season of admission, duration of fever, form of Kawasaki disease), laboratory (complete blood count, eosinophil count, serum biochemistry, C-reactive protein level, erythrocyte sedimentation rate [ESR], urinary analysis), echocardiographic and therapeutic data were evaluated retrospectively from the medical records...
May 2015: Turkish Journal of Pediatrics
Mehmet Riza Altiparmak, Sinan Trabulus, Ilker Inanc Balkan, Serkan Feyyaz Yalin, Nazim Denizli, Gonul Aslan, Hasan Erdal Doruk, Aynur Engin, Recep Tekin, Serhat Birengel, Birsen Durmaz Cetin, Ferhat Arslan, Vedat Turhan, Ali Mert
We aimed to investigate the demographic, clinical, diagnostic, treatment and outcome features of patients with urinary tuberculosis (UTB). Patients with UTB admitted to seven separate centers across Turkey between 1995 and 2013 were retrospectively evaluated. The diagnosis of UTB was made by the presence of any clinical finding plus positivity of one of the following: (1) acid-fast bacilli (AFB) in urine, (2) isolation of Mycobacterium tuberculosis, (3) polymerase chain reaction (PCR) for M. tuberculosis, (4) histopathological evidence for TB...
August 2015: Renal Failure
Anoush Azarfar, Yalda Ravanshad, Sepideh Bagheri, Mohammad Esmaeeli, Mahmood Malek Nejad
OBJECTIVE: The purpose of this study is to evaluate the clinical presentation, laboratory findings, and response to treatment in girls with labial adhesion younger than 23 months. MATERIAL AND METHODS: A retrospective chart review of all girls younger than 23 months with the diagnosis of labial adhesion was referred to Dr Sheikh children's clinic in Mashhad in northeast Iran between 1998 and 2013. RESULTS: Sixty-three patients were diagnosed with labial adhesion during the review period...
2015: Journal of the Turkish German Gynecological Association
Mohammad I Issack, Dan Jinerdeb
No abstract text is available yet for this article.
June 11, 2015: New England Journal of Medicine
David B Nelson, F Gary Cunningham, Marshall D Lindheimer
No abstract text is available yet for this article.
June 11, 2015: New England Journal of Medicine
Gilbert J Wise, Peter N Schlegel
New England Journal of Medicine, Volume 372, Issue 24, Page 2372-2373, June 2015.
June 11, 2015: New England Journal of Medicine
Toru Watanabe
Kawasaki disease (KD) is an acute, febrile vasculitis that predominantly develops in children ≤ 5 years of age and can lead to multiple organ injuries including the kidneys. Of these injuries, pyuria is a common feature of patients with KD, occurring in 30%-80% of patients. Sterile pyuria is most common in KD patients ≤ 1 year of age. KD patients with sterile pyuria exhibit more severe inflammatory reactions and may have sub-clinical renal injuries. Sterile pyuria in KD is associated with mononuclear cells (not neutrophils) in the urine...
May 8, 2015: World Journal of Clinical Pediatrics
Gilbert J Wise, Peter N Schlegel
New England Journal of Medicine, Volume 372, Issue 11, Page 1048-1054, March 2015.
March 12, 2015: New England Journal of Medicine
S D Sule, D G Moodalbail, J Burnham, B Fivush, S L Furth
INTRODUCTION: Children with systemic lupus erythematosus (SLE) have an increased prevalence of kidney disease compared to their adult counterparts. Our goal was to identify potential clinical and laboratory predictors of renal disease. METHODS: We performed a cohort study of incident and prevalent patients with SLE aged ≤19 years. Retrospective data from initial presentation until study enrollment was also collected. Laboratory and clinic data were recorded from each clinic visit including disease activity indices, autoantibodies, urinalyses, blood counts, and metabolic profile...
July 2015: Lupus
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