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Capsular contracture silicone implant

Paolo Montemurro, Mubashir Cheema, Per Hedén, Massimiliano Ferri, Alessandro Quattrini Li, Stefano Avvedimento
BACKGROUND: Extra full projection implants are used in a select group of aesthetic breast surgery patients. Their use is selective enough that they have not been included in long term manufacturer studies and the indications for their use have attracted much debate. Only a handful of studies have reported the outcomes from implantation of these devices. OBJECTIVES: We review our experience of using extra full projection anatomically shaped macrotextured silicone gel implants discussing our rationale, indications, and results...
November 11, 2016: Aesthetic Surgery Journal
Eric Swanson
BACKGROUND: The prevailing theory for capsular contracture after breast augmentation is a subclinical capsular infection. A capsulectomy, site change, and implant replacement are recommended. An open capsulotomy leaves the capsule in the patient. Theoretically, such a procedure would be ineffective because it does not remove the infected tissue. Recurrences occurred frequently in women treated in the 1970s when leaky silicone gel implants were in use. Open capsulotomy has not been studied in women implanted with third-generation devices...
October 2016: Plastic and Reconstructive Surgery. Global Open
Ze-Yuan Lei, Ting Liu, Wei-Juan Li, Xiao-Hua Shi, Dong-Li Fan
PURPOSE: Silicone rubber implants have been widely used to repair soft tissue defects and deformities. However, poor biocompatibility can elicit capsule formation, usually resulting in prosthesis contracture and displacement in long-term usage. To overcome this problem, this study investigated the properties of silicone rubber materials with or without a microgroove-patterned surface and with or without carbon (C)-ion implantation. MATERIALS AND METHODS: Atomic force microscopy, X-ray photoelectron spectroscopy, and a water contact angle test were used to characterize surface morphology and physicochemical properties...
2016: International Journal of Nanomedicine
Sedat Tatar, Ainura Sarybaeva, Kemal Fındıkcıoğlu, Cemile Merve Seymen, Çiğdem Elmas, Osman Latifoğlu
BACKGROUND: Silicon implants constitute a major part of plastic surgery practice. Although materials with high biocompatibility have been used around the implants, capsule formation still develops and progressive nature of this process results in capsule contraction. The aim of this study is to evaluate the effects of hyaluronic acid injected around the silicon block on the capsule structure. METHODS: Twenty Wistar albino rats were used in the study. Rats were divided into two main groups (group 1 and group 2) and two subgroups...
December 2016: Aesthetic Plastic Surgery
Jonathan Zelken, Jung-Ju Huang, Chih-Wei Wu, Yi-Ling Lin, Ming-Huei Cheng
The periareolar approach is limited by areolar diameter. Asian women typically have smaller areolae than Western women. Voluminous and form-stable silicone implants demand larger incisions. Zigzag transareolar approaches closely approximate the nipple and improve exposure, but scar appearance remains problematic, and there is a risk of ductal injury and capsular contracture. We prefer a zigzag incision that straddles the areolar border. Between 2013 and 2015, 11 augmentation mammoplasties (20 incisions) were performed through a transareolar-periareolar (TAPA) incision...
September 2016: Plastic and Reconstructive Surgery. Global Open
Man Koon Suh, Kyo Ho Lee, Aram Harijan, Hyung-Gu Kim, Euicheol C Jeong
BACKGROUND: Alloplastic materials are a mainstay in Asian rhinoplasty. However, the outline of alloplastic implants can become conspicuous over time in rhinoplasty patients, which is a significant cause for revision. In revision rhinoplasty, alloplastic materials can remain a viable and affordable option in Asian patients. The acellular dermal matrices (ADM) are often used to interface between the silicone material and the skin envelope. This study assesses histologic changes following implantation of ADM-covered silicone material in rats...
October 14, 2016: Journal of Craniofacial Surgery
Stefano Pompei, Dora Evangelidou, Floriana Arelli, Gianluigi Ferrante
BACKGROUND: First-generation polyurethane foam-coated breast implants were associated with a low risk of capsular contracture (CC), but the risk of CC with modern polyurethane-coated silicone implants has not been established. OBJECTIVES: The authors sought to determine the long-term rates of CC after primary breast augmentation with Microthane, a polyurethane-coated silicone gel implant. METHODS: A total of 131 patients (255 breasts) were evaluated in a retrospective study...
November 2016: Aesthetic Surgery Journal
Vilberto J Vieira, Armando D'Acampora, Fernanda S Neves, Paulo R Mendes, Zulmar A DE Vasconcellos, Rodrigo D'Eça Neves, Claudia P Figueiredo
Breast augmentation with silicone implants is one of the most common procedures performed by plastic surgeons around the world. Capsular contracture is a frequent complication in breast augmentation and reconstructive surgery, that requires invasive intervention. The inflammatory response to implanted mammary prostheses appears to be directly associated to capsular contracture. This review discusses the evidences from rat models studies, on the role of inflammation and fibrosis in capsular contraction and its relation to silicone breast implants surface...
September 2016: Anais da Academia Brasileira de Ciências
Patricia McGuire, Neal R Reisman, Diane K Murphy
BACKGROUND: Natrelle® 410 silicone breast implants are approved in the US for breast augmentation, reconstruction, and revision. METHODS: In two ongoing, prospective, multicenter 10-year studies, 17,656 subjects received Natrelle 410 implants for augmentation (n=5059), revision-augmentation (n=2632), reconstruction (n=7502), or revision-reconstruction (n=2463). Capsular contracture, implant malposition, and late seroma were documented. Cox proportional hazards regression analyses evaluated potential associations between subject-, implant-, and surgery-related factors and these complications...
September 10, 2016: Plastic and Reconstructive Surgery
Kyu Jin Chung, Ki Rin Park, Jun Ho Lee, Tae Gon Kim, Yong-Ha Kim
Capsular fibrosis and contracture occurs in most breast reconstruction patients who undergo radiotherapy, and there is no definitive solution for its prevention. Simvastatin was effective at reducing fibrosis in various models. Peri-implant capsular formation is the result of tissue fibrosis development in irradiated breasts. The purpose of this study was to examine the effect of simvastatin on peri-implant fibrosis in rats. Eighteen male Sprague-Dawley rats were allocated to an experimental group (9 rats, 18 implants) or a control group (9 rats, 18 implants)...
August 2016: Journal of Korean Medical Science
Dennis C Hammond, William P Schmitt
BACKGROUND: A variety of saline and silicone implants have been introduced over the years to optimize the shape, aesthetic result and safety profile for use in breast surgery. The McGhan Style 153 dual-lumen silicone implant represented an early generation of anatomically shaped implants later removed from the market due to a high rate of rupture. This study reports long term outcomes and complications, including a revised rupture rate, and discusses potential mechanisms of implant failure and their implications for future implant design...
September 2016: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
Sena Kim, Moonsang Ahn, Yibo Piao, Yooseok Ha, Dae-Kyoung Choi, Min-Hee Yi, Nara Shin, Dong Woon Kim, Sang-Ha Oh
BACKGROUND: One of the most serious complications of breast surgery using implants is capsular contracture. Several preventive treatments have been introduced; however, the mechanism of capsule formation has not been resolved completely. We previously identified negative effects of botulinum toxin type A (BTX-A) on capsule formation, expression of TGF-β1 and differentiation of fibroblasts into myofibroblasts. Thus, we investigated how to prevent capsule formation by BTX-A, particularly via TGF-β1 signaling, in human fibroblasts...
July 5, 2016: Plastic and Reconstructive Surgery
Shasha Li, Liwen Ren, Haiqian Xu, Di Jia, Sai Luo, Lijun Hao, Dan Yang
BACKGROUND: Capsular contracture is a serious complication that occurs after breast implant surgery. This study was performed to confirm that medical chitosan (MC) affects capsule formation and elucidates a possible mechanism. MATERIALS AND METHODS: In this study, we used 18 female adult New Zealand White rabbits. In each rabbit, two silicone implants were placed under the pectoralis muscle layer on both sides (one side was included in the experimental group and the other side was included in the control group)...
August 2016: Aesthetic Plastic Surgery
Sebastian Fischer, Christoph Hirche, Yannick Diehm, Kristo Nuutila, Jurij Kiefer, Emre Gazyakan, Ericka M Bueno, Thomas Kremer, Ulrich Kneser, Bohdan Pomahac
BACKGROUND: The fibrotic capsule that surrounds silicone implants consists mainly of collagen. The FDA-approved collagenase of the bacterium clostridium histolyticum provides a reasonable treatment option. Safety and efficacy at the female breast site must be evaluated before clinical utilization. MATERIALS AND METHODS: We incubated 20 samples of fibrotic capsule as well as 12 full thickness skin grafts harvested from the female breast site for 24 hours with different doses of collagenase...
2016: PloS One
Nicola Rocco, Corrado Rispoli, Lorenzo Moja, Bruno Amato, Loredana Iannone, Serena Testa, Andrea Spano, Giuseppe Catanuto, Antonello Accurso, Maurizio B Nava
BACKGROUND: Breast cancer is the most common cancer in women worldwide, and is a leading cause of cancer death among women. Prophylactic or curative mastectomy is often followed by breast reconstruction for which there are several surgical approaches that use breast implants with which surgeons can restore the natural feel, size and shape of the breast. OBJECTIVES: To assess the effects of different types of breast implants on capsular contracture, surgical short- and long-term complications, postoperative satisfaction level and quality of life in women who have undergone reconstructive breast surgery after mastectomy...
May 16, 2016: Cochrane Database of Systematic Reviews
Jacob G Unger, Jennel M Carreras, Purushottam Nagarkar, Haneol S Jeong, William Carpenter
BACKGROUND: Implant-based breast reconstruction is performed with both saline and silicone. In 2001, a study was conducted in which a novel implant made of highly cohesive silicone gel in anatomical shape was used. It differs from others because it holds its anatomical shape and forces tissue to conform to the implant. METHODS: Two hundred twelve consecutive patients who underwent reconstruction with Allergan 410 cohesive gel anatomical implants were enrolled prospectively over a 12-year period...
September 2016: Plastic and Reconstructive Surgery
Lee Seng Khoo, Henrique N Radwanski, Vasco Senna-Fernandes, Nsingi Nsosolo Antônio, Leonardo Luiz Fernandes Fellet, Ivo Pitanguy
Background. Is the use of intraoperative breast sizers beneficial for plastic surgeons or do they result in higher complication rates? Methods. This is a retrospective study of 416 consecutive cases of primary breast augmentation with silicone implants at the Plastic Surgery Service of Professor Ivo Pitanguy at the 38th Infirmary Santa Casa Misericórdia Hospital, Rio De Janeiro, from January 2011 to March 2014. 212 cases (51%) were carried out with use of intraoperative breast sizers with 204 cases (49%) without the use of implant sizers...
2016: Plastic Surgery International
Emily E Anderson, Egon Perilli, Colin J Carati, Karen J Reynolds
A major complication of silicone breast implants is the formation of a capsule around the implant known as capsular contracture which results in the distortion of the implant. Recently, a mouse model for studying capsular contracture was examined using micro-computed tomography (micro-CT), however, only qualitative changes were reported. The aim of this study was to develop a quantitative method for comparing the shape changes of silicone implants using in vivo micro-CT. Mice were bilaterally implanted with silicone implants and underwent ionizing radiation to induce capsular contracture...
April 18, 2016: Journal of Biomedical Materials Research. Part B, Applied Biomaterials
Tam T Quinn, George S Miller, Marie Rostek, Miguel S Cabalag, Warren M Rozen, David J Hunter-Smith
BACKGROUND: Despite 82% of patients reporting psychosocial improvement following breast reconstruction, only 33% patients choose to undergo surgery. Implant reconstruction outnumbers autologous reconstruction in many centres. METHODS: A systematic review of the literature was undertaken. Inclusion required: (I) Meta-analyses or review articles; (II) adult patients aged 18 years or over undergoing alloplastic breast reconstruction; (III) studies including outcome measures; (IV) case series with more than 10 patients; (V) English language; and (VI) publication after 1(st) January, 2000...
April 2016: Gland Surgery
Sammy Sinno, Jessica B Chang, Nicholas D Brownstone, Pierre B Saadeh, Simeon Wall
BACKGROUND: Augmentation gluteoplasty has been performed more frequently in the past decade, with over 21,000 procedures performed in the past year alone. The most popular methods for buttock augmentation involve silicone prostheses and autologous fat grafting. A comparison of complications of these two techniques does not exist in our literature. METHODS: The PubMed, MEDLINE, and Cochrane databases were searched through April of 2015 for studies that achieved buttock augmentation through the use of silicone implant placement or autologous lipoinjection...
April 2016: Plastic and Reconstructive Surgery
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