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Postprandial syndrome

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https://www.readbyqxmd.com/read/28211280/gastric-invagination-in-adults-as-a-rare-cause-of-constitutional-syndrome
#1
Cristina Dávila Arias, Ana Milena Muñoz, María Ángeles Valero González, Mariano Céspedes Mas
This article describes and illustrates the case of an adult patient with clinical symptoms of constitutional syndrome, postprandial discomfort and a mass in the left lateral abdominal region caused by a gastric intussusception with a fundal adenoma as the head of the invagination. The intussusception was diagnosed by MRI (magnetic resonance imaging).
February 2017: Revista Española de Enfermedades Digestivas
https://www.readbyqxmd.com/read/28209386/dietary-therapy-in-heart-failure-with-preserved-ejection-fraction-and-or-left-ventricular-diastolic-dysfunction-in-patients-with-metabolic-syndrome
#2
REVIEW
Helene von Bibra, Alexander Ströhle, Martin St John Sutton, Nicolai Worm
BACKGROUND: Heart failure is an ongoing epidemic of left ventricular (LV) dilatation and/or dysfunction due to the increasing prevalence of predisposing risk factors such as age, physical inactivity, (abdominal) obesity, and type-2-diabetes. Approximately half of these patients have diastolic heart failure (HFpEF). The prognosis of HFpEF is comparable to that of systolic heart failure, but without any known effective treatment. DIASTOLIC DYSFUNCTION: A biomathematically corrected diagnostic approach is presented that quantifies diastolic dysfunction via the predominant age dependency of LV diastolic function and unmasks (metabolic) risk factors, that are independent of age and, therefore, potential targets for therapy...
January 5, 2017: International Journal of Cardiology
https://www.readbyqxmd.com/read/28192847/-gastroparesis-in-noonan-syndrome
#3
Konstantin G Heimrich, Falk Gühne, Solveig Schulz, Stephanie Mutschke, Andreas Stallmach, Jessica Rüddel
We present a case of a 26-year-old female patient with bloating, postprandial nausea and recurrent vomiting after solid food intake. A gastric emptying scintigraphy showed a delayed gastric emptying, defining gastroparesis. Because of her past medical history of short stature and pulmonary stenosis, we initiated genetic counseling where the diagnosis of Noonan syndrome was made. Dietary therapy and medication with domperidone quickly led to relief of the discomfort due to gastroparesis. However, prokinetics are not indicated for long-term therapy, as cardiac arrhythmia may occur...
February 2017: Zeitschrift Für Gastroenterologie
https://www.readbyqxmd.com/read/28190890/c-peptide-baseline-and-postprandial-insulin-resistance-after-a-carbohydrate-rich-test-meal-evidence-for-an-increased-insulin-clearance-in-pcos-patients
#4
J Stassek, J Erdmann, F Ohnolz, F D Berg, M Kiechle, V Seifert-Klauss
Introduction Known characteristics of patients with PCOS include infertility, menstrual disorders, hirsutism and also often insulin resistance. These symptoms increase with increasing body weight. In the LIPCOS study (Lifestyle Intervention for Patients with Polycystic Ovary Syndrome [PCOS]) long-term changes of the PCOS in dependence on pregnancy and parenthood were systematically assessed. In the framework of the LIPCOS study, PCOS patients were given a standardised carbohydrate-rich test meal in order to examine glucose homeostasis and insulin secretion...
January 2017: Geburtshilfe und Frauenheilkunde
https://www.readbyqxmd.com/read/28160607/overlap-between-irritable-bowel-syndrome-and-functional-dyspepsia-including-subtype-analyses
#5
Yoon Jin Choi, Nayoung Kim, Hyuk Yoon, Cheol Min Shin, Young Soo Park, Jin-Wook Kim, Yong Sung Kim, Dong Ho Lee, Hyun Chae Jung
BACKGROUND AND AIM: Coexistent gastrointestinal symptom profiles and prevalence or associated factors for the overlap between each functional dyspepsia (FD) and irritable bowel syndrome (IBS) group remain unclear. Thus, the aim of the present study was to evaluate the clinicodemographic features of FD, IBS, and IBS-FD overlap and assess the risk factors thereof, including subtype and genetic polymorphisms for IBS-FD. METHODS: Consecutive patients were enrolled from the outpatient Gastroenterology clinics of Bundang Seoul National University Hospitals in Korea...
February 4, 2017: Journal of Gastroenterology and Hepatology
https://www.readbyqxmd.com/read/28122929/a-systematic-review-of-the-effects-of-plant-compared-with-animal-protein-sources-on-features-of-metabolic-syndrome
#6
REVIEW
Tristan Chalvon-Demersay, Dalila Azzout-Marniche, Judith Arfsten, Léonie Egli, Claire Gaudichon, Leonidas G Karagounis, Daniel Tomé
Dietary protein may play an important role in the prevention of metabolic dysfunctions. However, the way in which the protein source affects these dysfunctions has not been clearly established. The aim of the current systematic review was to compare the impact of plant- and animal-sourced dietary proteins on several features of metabolic syndrome in humans. The PubMed database was searched for both chronic and acute interventional studies, as well as observational studies, in healthy humans or those with metabolic dysfunctions, in which the impact of animal and plant protein intake was compared while using the following variables: cholesterolemia and triglyceridemia, blood pressure, glucose homeostasis, and body composition...
January 25, 2017: Journal of Nutrition
https://www.readbyqxmd.com/read/28093873/diagnostic-and-management-challenges-from-childhood-puberty-through-to-transition-in-severe-insulin-resistance-due-to-insulin-receptor-mutations
#7
Christina Wei, Christine P Burren
Two Caucasian girls, both of normal weight and body mass indices, were diagnosed with type A insulin resistance (IR) in childhood. Case 1 presented with premature adrenarche aged 7 years, then by age 12 years had hirsutism, acne, acanthosis nigricans, and asymptomatic diabetes. Subsequent investigation revealed raised adiponectin (15.3 mg/L) and heterozygous p.Pro1205Leu mutation in the INSR gene encoding the insulin receptor. She experienced postprandial hypoglycaemia on metformin; acarbose was trialled and discontinued aged 16 years, as she became normoglycaemic...
January 17, 2017: Pediatric Diabetes
https://www.readbyqxmd.com/read/28080913/liver-ultrasonography-in-dolphins-use-of-ultrasonography-to-establish-a-technique-for-hepatobiliary-imaging-and-to-evaluate-metabolic-disease-associated-liver-changes-in-bottlenose-dolphins-tursiops-truncatus
#8
Kelsey E Seitz, Cynthia R Smith, Stanley L Marks, Stephanie K Venn-Watson, Marina Ivančić
The objective of this study was to establish a comprehensive technique for ultrasound examination of the dolphin hepatobiliary system and apply this technique to 30 dolphins to determine what, if any, sonographic changes are associated with blood-based indicators of metabolic syndrome (insulin greater than 14 μIU/ml or glucose greater than 112 mg/dl) and iron overload (transferrin saturation greater than 65%). A prospective study of individuals in a cross-sectional population with and without elevated postprandial insulin levels was performed...
December 2016: Journal of Zoo and Wildlife Medicine: Official Publication of the American Association of Zoo Veterinarians
https://www.readbyqxmd.com/read/28079239/prevalence-of-dyspeptic-symptoms-and-heartburn-of-adults-in-belo-horizonte-brazil
#9
Alessandra Maciel Almeida, Luísa Alvarenga Guerra Martins, Patrícia Liz Terenzi Cunha, Viviane Willig Brasil, Lucas Galuppo Fernandes Félix, Maria do Carmo Friche Passos
BACKGROUND: - Medical literature has shown dyspepsia and heartburn-related symptoms occur among 15% to 40% of the population. These symptoms can occur at any age and are more prevalent in women. OBJECTIVE: - Investigate the prevalence of dyspeptic symptoms and heartburn among individuals over 18. METHODS: - Individuals over 18 were randomly selected in public venues in Belo Horizonte/MG to participate. A standardized questionnaire that included questions related to social-demographic characteristics, eating habits, digestive symptoms, medical appointments, medications, exams, previous surgeries and comorbidities was applied...
January 2017: Arquivos de Gastroenterologia
https://www.readbyqxmd.com/read/28078818/objectively-diagnosing-rumination-syndrome-in-children-using-esophageal-ph-impedance-and-manometry
#10
M M J Singendonk, J M Oors, A J Bredenoord, T I Omari, R J van der Pol, M J Smits, M A Benninga, M P van Wijk
BACKGROUND: Rumination syndrome is characterized by recurrent regurgitation of recently ingested food into the mouth. Differentiation with other diagnoses and gastroesophageal reflux disease (GERD) in particular, is difficult. Recently, objective pH-impedance (pH-MII) and manometry criteria were proposed for adults. The aim of this study was to determine diagnostic ambulatory pH-MII and manometry criteria for rumination syndrome in children. METHODS: Clinical data and 24-hour pH-MII and manometry recordings of children with a clinical suspicion of rumination syndrome were reviewed...
January 12, 2017: Neurogastroenterology and Motility: the Official Journal of the European Gastrointestinal Motility Society
https://www.readbyqxmd.com/read/28072728/upper-gastrointestinal-symptoms-in-autoimmune-gastritis-a-cross-sectional-study
#11
Marilia Carabotti, Edith Lahner, Gianluca Esposito, Maria Carlotta Sacchi, Carola Severi, Bruno Annibale
Autoimmune gastritis is often suspected for its hematologic findings, and rarely the diagnosis is made for the presence of gastrointestinal symptoms. Aims of this cross-sectional study were to assess in a large cohort of patients affected by autoimmune gastritis the occurrence and the pattern of gastrointestinal symptoms and to evaluate whether symptomatic patients are characterized by specific clinical features.Gastrointestinal symptoms of 379 consecutive autoimmune gastritis patients were systematically assessed and classified following Rome III Criteria...
January 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28070639/effects-of-a-diet-rich-in-arabinoxylan-and-resistant-starch-compared-with-a-diet-rich-in-refined-carbohydrates-on-postprandial-metabolism-and-features-of-the-metabolic-syndrome
#12
Anne Grethe Schioldan, Søren Gregersen, Stine Hald, Ann Bjørnshave, Mette Bohl, Bolette Hartmann, Jens Juul Holst, Hans Stødkilde-Jørgensen, Kjeld Hermansen
PURPOSE: Low intake of dietary fibre is associated with the development of type 2 diabetes. Dyslipidaemia plays a key role in the pathogenesis of type 2 diabetes. Knowledge of the impact of dietary fibres on postprandial lipaemia is, however, sparse. This study aimed in subjects with metabolic syndrome to assess the impact on postprandial lipaemia and features of the metabolic syndrome of a healthy carbohydrate diet (HCD) rich in cereal fibre, arabinoxylan and resistant starch compared to a refined-carbohydrate western-style diet (WSD)...
January 9, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28058964/fasting-and-postprandial-plasma-citrulline-and-the-correlation-to-intestinal-function-evaluated-by-72-hour-metabolic-balance-studies-in-short-bowel-jejunostomy-patients-with-intestinal-failure
#13
Hilde Fjermestad, Mark Hvistendahl, Palle Bekker Jeppesen
BACKGROUND: Fasting plasma citrulline (p-citrulline) is a marker of functional enterocyte mass. However, the optimal timing of measurement in relation to meals has yet to be clarified. Furthermore, p-citrulline has been proposed to be a surrogate marker for small bowel length and intestinal absorption parameters in short bowel syndrome patients with intestinal failure (SBS-IF). MATERIALS AND METHODS: Eight patients with SBS-IF and 8 healthy controls (HCs) were given a standardized mixed test meal, and p-citrulline was measured 15 minutes before and 60, 120, and 180 minutes after completion of the meal...
January 1, 2017: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/28050031/editorial-moving-away-from-focussing-on-gastric-pathophysiology-in-functional-dyspepsia-new-insights-and-therapeutic-implications
#14
Nicholas J Talley
Functional dyspepsia (FD) is a prevalent syndrome that affects up to one in six Americans, although misdiagnosis as gastroesophageal reflux disease may be common. Early satiety, postprandial fullness, and epigastric pain or burning are the cardinal symptoms. Traditionally, FD has been blamed on gastric dysfunction and much research effort has focussed on unlocking the gastric pathophysiology. New research suggests gastric dysfunction has only a minor role in the pathogenesis in many cases, and the focus has begun to shift to evaluation of duodenal feedback and subtle inflammation including duodenal eosinophilia...
January 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/28049238/the-curves-exercise-suppresses-endotoxemia-in-korean-women-with-obesity
#15
Seon Ah Jin, Sun Kyeong Kim, Hee Jung Seo, Mijoo Kim, Kye Taek Ahn, Jun Hyung Kim, Jae Hyeong Park, Jae Hwan Lee, Si Wan Choi, Jin Ok Jeong
Obesity and metabolic syndrome is a worldwide pandemic and associated with high cardiovascular risk. Metabolic endotoxemia (ME) is thought to be an underlying molecular mechanism. It triggers toll-like receptor 4-mediated inflammatory adipokines and causes a chronic low grade inflammatory status, which results in cardiovascular risk increase. Exercise is the best nonpharmacological treatment to improve prognosis. In this study, we examined the circulating endotoxin level in Korean obese women and investigated effects of exercise on it...
February 2017: Journal of Korean Medical Science
https://www.readbyqxmd.com/read/27997268/impaired-apob-lipoprotein-and-triglyceride-metabolism-in-obese-adolescents-with-polycystic-ovary-syndrome
#16
D F Vine, Y Wang, M M Jetha, Gdc Ball, S D Proctor
CONTEXT: Adolescents with Polycystic Ovary Syndrome (PCOS) have atherogenic dyslipidemia and increased cardiovascular disease (CVD) risk, and this is exacerbated in obesity. OBJECTIVE: To determine and compare fasting and non-fasting lipid and ApoB-lipoprotein metabolism in three groups of adolescent girls: i) healthy-weight controls, ii) obese without PCOS (obese-control) and iii) obese with PCOS (obese-PCOS). DESIGN, SETTING AND PARTICIPANTS: Participants aged 12-17 years were recruited for this cross-sectional study from a pediatric weight management clinic and the local community in Alberta, Canada...
December 20, 2016: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/27991713/roles-of-the-gut-in-the-metabolic-syndrome-an-overview
#17
REVIEW
L Fändriks
The metabolic syndrome is a cluster of risk factors (central obesity, hyperglycaemia, dyslipidaemia and arterial hypertension), indicating an increased risk of diabetes, cardiovascular disease and premature mortality. The gastrointestinal tract is seldom discussed as an organ system of principal importance for metabolic diseases. The present overview connects various metabolic research lines into an integrative physiological context in which the gastrointestinal tract is included. Strong evidence for the involvement of the gut in the metabolic syndrome derives from the powerful effects of weight-reducing (bariatric) gastrointestinal surgery...
December 19, 2016: Journal of Internal Medicine
https://www.readbyqxmd.com/read/27987919/number-of-branch-points-in-%C3%AE-limit-dextrins-impact-glucose-generation-rates-by-mammalian-mucosal-%C3%AE-glucosidases
#18
Byung-Hoo Lee, Bruce R Hamaker
α-Amylase first hydrolyzes starch structures to linear maltooligosaccharides and branched α-limit dextrins, then complete hydrolysis to glucose takes place through the mucosal α-glucosidases. In this study, we hydrolyzed waxy corn starch (WCS) by human pancreatic α-amylase to determine the digestion and structural properties of different size fractions of the branched α-limit dextrins. The α-amylolyzed WCS was separated by size exclusion chromatography, and the analyzed chromatograms showed four main hydrolyzate fractions...
February 10, 2017: Carbohydrate Polymers
https://www.readbyqxmd.com/read/27958284/pathophysiological-abnormalities-in-functional-dyspepsia-subgroups-according-to-the-rome-iii-criteria
#19
H Vanheel, F Carbone, L Valvekens, M Simren, H Tornblom, T Vanuytsel, L Van Oudenhove, J Tack
OBJECTIVES: The Rome III criteria proposed to subdivide functional dyspepsia (FD) into a postprandial distress syndrome (PDS) group, characterized by the presence of postprandial fullness and/or early satiety, and an epigastric pain syndrome (EPS) group, characterized by the presence of epigastric pain and/or epigastric burning. It has been suggested that different pathophysiological mechanisms underlie the symptom presentations in these subgroups that might determine treatment choices...
January 2017: American Journal of Gastroenterology
https://www.readbyqxmd.com/read/27958282/distinct-abnormalities-of-small-bowel-and-regional-colonic-volumes-in-subtypes-of-irritable-bowel-syndrome-revealed-by-mri
#20
Ching Lam, Gemma Chaddock, Luca Marciani Laurea, Carolyn Costigan, Eleanor Cox, Caroline Hoad, Susan Pritchard, Penny Gowland, Robin Spiller
OBJECTIVES: Non-invasive biomarkers which identify different mechanisms of disease in subgroups of irritable bowel syndrome (IBS) could be valuable. Our aim was to seek useful magnetic resonance imaging (MRI) parameters that could distinguish each IBS subtypes. METHODS: 34 healthy volunteers (HV), 30 IBS with diarrhea (IBS-D), 16 IBS with constipation (IBS-C), and 11 IBS with mixed bowel habit (IBS-M) underwent whole-gut transit and small and large bowel volumes assessment with MRI scans from t=0 to t=360 min...
December 13, 2016: American Journal of Gastroenterology
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