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https://www.readbyqxmd.com/read/28346731/exploring-the-influence-of-mpa-capped-cdte-quantum-dots-on-the-structure-and-function-of-lysozyme-probing-by-spectroscopic-and-calorimetric-methods
#1
Lining Zhao, Tao Sun, Xun Zhang, Wei Song, Rutao Liu
The effect of 3-mercaptopropionic acid (MPA)-capped CdTe quantum dots (QDs) on lysozyme was systematically investigated by spectroscopic methods, enzyme activity assay, and calorimetry techniques. Results show that the MPA-capped CdTe QDs binded to lysozyme through van der Walls forces and hydrogen bondings, causing the decrement of α-helical content (∼7%) and increment of β-sheet content (∼11%) of lysozyme. The binding caused static quenching of the fluorescence, while the microenvironment of aromatic amino acid residues did not show any significant alteration...
March 27, 2017: Journal of Biochemical and Molecular Toxicology
https://www.readbyqxmd.com/read/28346014/intestinal-absorption-and-renal-reabsorption-of-calcium-throughout-postnatal-development
#2
Megan R Beggs, R Todd Alexander
Calcium is vital for many physiological functions including bone mineralization. Postnatal deposition of calcium into bone is greatest in infancy and continues through childhood and adolescence until peek mineral density is reached in early adulthood. Thereafter, bone mineral density remains static until it eventually declines in later life. A positive calcium balance, i.e. more calcium absorbed than excreted, is crucial to bone deposition during growth and thus to peek bone mineral density. Dietary calcium is absorbed from the intestine into the blood...
April 2017: Experimental Biology and Medicine
https://www.readbyqxmd.com/read/28345876/engineering-cellular-microenvironments-with-photo-and-enzymatically-responsive-hydrogels-toward-biomimetic-3d-cell-culture-models
#3
Roger Y Tam, Laura J Smith, Molly S Shoichet
Conventional cell culture techniques using 2D polystyrene or glass have provided great insight into key biochemical mechanisms responsible for cellular events such as cell proliferation, differentiation, and cell-cell interactions. However, the physical and chemical properties of 2D culture in vitro are dramatically different than those found in the native cellular microenvironment in vivo. Cells grown on 2D substrates differ significantly from those grown in vivo, and this explains, in part, why many promising drug candidates discovered through in vitro drug screening assays fail when they are translated to in vivo animal or human models...
March 27, 2017: Accounts of Chemical Research
https://www.readbyqxmd.com/read/28345698/ethylcellulose-oleogels-for-lipophilic-bioactive-delivery-effect-of-oleogelation-on-in-vitro-bioaccessibility-and-stability-of-beta-carotene
#4
Chloe M O Sullivan, Maya Davidovich-Pinhas, Amanda J Wright, Shai Barbut, Alejandro G Marangoni
The in vitro lipolysis and β-carotene (BC) transfer from oil to aqueous phase of canola oil ethylcellulose (EC) oleogels were measured using a static monocompartmental model simulating oral, gastric, and duodenal digestive stages. The effects of EC oleogelation on gel in vitro digestibility were examined, using un-structured canola oil as a control. The physicochemical properties of oleogels containing BC were also measured. It was found that oleogels made with 10% 10 cP and 10% 20 cP did not differ significantly in their extent of lipolysis or BC transfer compared to canola oil; however 10% 45 cP and 15...
March 27, 2017: Food & Function
https://www.readbyqxmd.com/read/28345378/probing-the-behavior-of-bovine-serum-albumin-upon-binding-to-atenolol-insights-from-spectroscopic-and-molecular-docking-approaches
#5
Tuo-Ying Jiang, Kai-Li Zhou, Yan-Yue Lou, Dong-Qi Pan, Jie-Hua Shi
Molecular interaction of atenolol, a selective β1 receptor antagonist with the major carrier protein, bovine serum albumin (BSA), was investigated under imitated physiological conditions (pH 7.4) by means of fluorescence spectroscopy, UV absorption spectroscopy, Fourier transform infrared spectroscopy (FT-IR), and molecular modeling studies. The steady-state fluorescence spectra manifested that static type, due to formation of the atenolol-BSA complex, was the dominant mechanism for fluorescence quenching...
March 27, 2017: Journal of Biomolecular Structure & Dynamics
https://www.readbyqxmd.com/read/28345273/tuning-hole-and-electron-transfer-from-photo-excited-cdse-quantum-dot-to-phenol-derivatives-effect-of-electron-donating-and-withdrawing-moiety
#6
Hirendra Nath Ghosh, Tushar Debnath, Deepa Sebastian, Sourav Maiti
Charge transfer processes from photo-excited CdSe QDs to phenol derivatives with electron donating (4-methoxy) and electron withdrawing (4-nitro) moiety have been demonstrated by using steady state and time-resolved emission and femto-second transient absorption spectroscopy. Steady state and time-resolved emission studies suggest that in presence of both 4-nitro phenol (4NP) and 4-methoxy phenol (4MP) CdSe QDs luminescence gets quenched. Stern-Volmer analysis suggests both static and dynamic mechanisms are active for both the QD/phenol composites...
March 27, 2017: Chemistry: a European Journal
https://www.readbyqxmd.com/read/28345150/decoding-facial-expressions-based-on-face-selective-and-motion-sensitive-areas
#7
Yin Liang, Baolin Liu, Junhai Xu, Gaoyan Zhang, Xianglin Li, Peiyuan Wang, Bin Wang
Humans can easily recognize others' facial expressions. Among the brain substrates that enable this ability, considerable attention has been paid to face-selective areas; in contrast, whether motion-sensitive areas, which clearly exhibit sensitivity to facial movements, are involved in facial expression recognition remained unclear. The present functional magnetic resonance imaging (fMRI) study used multi-voxel pattern analysis (MVPA) to explore facial expression decoding in both face-selective and motion-sensitive areas...
March 27, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/28344445/effects-of-static-and-dynamic-stretching-on-the-isokinetic-peak-torques-and-electromyographic-activities-of-the-antagonist-muscles
#8
Abdullah Serefoglu, Ufuk Sekir, Hakan Gür, Bedrettin Akova
The aim of this study was to investigate if static and dynamic stretching exercises of the knee muscles (quadriceps and hamstring muscles) have any effects on concentric and eccentric isokinetic peak torques and electromyographic amplitudes (EMG) of the antagonist muscles. Twenty healthy male athletes (age between 18-30 years) voluntarily participated in this study. All of the subjects visited the laboratory to complete the following intervention in a randomized order on 5 separate days; (a) non-stretching (control), (b) static stretching of the quadriceps muscles, (c) static stretching of the hamstring muscles, (d) dynamic stretching of the quadriceps muscles, and (e) dynamic stretching of the hamstring muscles...
March 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28344314/low-dimensional-string-like-relaxation-underpins-superionic-conduction-in-fluorites-and-related-structures
#9
Ajay Annamareddy, Jacob Eapen
Among the superionic conductors that show a Faraday transition - the continuous increase in the ionic conductivity over a range of temperatures - the fluorite structures have enjoyed incisive examinations over the past four decades; yet the fundamental nature of superionicity has remained largely inconclusive. Departing from the traditional quasi-static defect framework, we provide weighty evidence for string-like dynamical structures that govern the fast ion conduction process in fluorites. We show that lower temperatures encourage the growth of longer but slowly relaxing strings and vice-versa - a direct manifestation of heterogeneous dynamics...
March 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28343985/functional-connectivity-dynamically-evolves-on-multiple-time-scales-over-a-static-structural-connectome-models-and-mechanisms
#10
REVIEW
Joana Cabral, Morten Kringelbach, Gustavo Deco
Over the last decade, we have observed a revolution in brain structural and functional Connectomics. On one hand, we have an ever-more detailed characterization of the brain's white matter structural connectome. On the other, we have a repertoire of consistent functional networks that form and dissipate over time during rest. Despite the evident spatial similarities between structural and functional connectivity, understanding how different time-evolving functional networks spontaneously emerge from a single structural network requires analyzing the problem from the perspective of complex network dynamics and dynamical system's theory...
March 23, 2017: NeuroImage
https://www.readbyqxmd.com/read/28343780/propagation-of-brazilian-zika-virus-strains-in-static-and-suspension-cultures-using-vero-and-bhk-cells
#11
Alexander Nikolay, Leda R Castilho, Udo Reichl, Yvonne Genzel
The recent spread of Zika virus (ZIKV) in the Americas and the Pacific has reached alarming levels in more than 60 countries. However, relatively little is known about the disease on a virological and epidemiological level and its consequences for humans. Accordingly, a large demand for in vitro derived Brazilian ZIKV material to support in vitro and in vivo studies has arisen. However, a prompt supply of ZIKV and ZIKV antigens cannot be guaranteed as the production of this virus typically using Vero or C6/36 cell lines remains challenging...
March 23, 2017: Vaccine
https://www.readbyqxmd.com/read/28343565/thermal-tolerance-and-preferred-temperature-range-of-juvenile-meagre-acclimated-to-four-temperatures
#12
Mehmet Kır, Murat Can Sunar, Barış Can Altındağ
The present study reports the temperature tolerance, estimated using dynamic and static methodologies, and preferred temperature range, based on oxygen consumption rate (OCR), of juvenile meagre (Argyrosomus regius) (Asso, 1801) (3.4±0.9g) after 30 days of acclimation at 18, 22, 26 and 30°C. Meagre has dynamic and static thermal tolerance zones of 551°C(2) and 460°C(2), respectively and is a low resistance fish species, with a resistance zone area of 87°C(2). The OCR of juvenile meagre at the above acclimation temperatures was 370, 410, 618 and 642mgh(-1)kg(-)(1), respectively, and is significantly different (P<0...
April 2017: Journal of Thermal Biology
https://www.readbyqxmd.com/read/28342975/biomechanical-testing-of-a-peek-based-dynamic-instrumentation-device-in-a-lumbar-spine-model
#13
Christian Herren, Agnes Beckmann, Sabine Meyer, Miguel Pishnamaz, Marion Mundt, Rolf Sobottke, Andreas Prescher, Marcus Stoffel, Bernd Markert, Philipp Kobbe, Hans-Christoph Pape, Peer Eysel, Jan Siewe
BACKGROUND: The purpose of this study was to investigate the range-of-motion after posterior polyetheretherketone-based rod stabilisation combined with a dynamic silicone hinge in order to compare it with titanium rigid stabilisation. METHODS: Five human cadaveric lumbar spines with four vertebra each (L2 to L5) were tested in a temperature adjustable spine-testing set-up in four trials: (1) native measurement; (2) kinematics after rigid monosegmental titanium rod instrumentation with anterior intervertebral bracing of the segment L4/5; (3) kinematics after hybrid posterior polyetheretherketone rod instrumentation combined with a silicone hinge within the adjacent level (L3/4) and (4) kinematics after additional decompression with laminectomy of L4 and bilateral resection of the inferior articular processes (L3)...
March 18, 2017: Clinical Biomechanics
https://www.readbyqxmd.com/read/28342353/preparation-of-a-surface-grafted-imprinted-ceramic-membrane-for-selective-separation-of-molybdate-anion-from-water-solutions
#14
Jianxian Zeng, Zhihui Dong, Zhe Zhang, Yuan Liu
A surface-grafted imprinted ceramic membrane (IIP-PVI/CM) for recognizing molybdate (Mo(VI)) anion was prepared by surface-initiated graft-polymerization. Firstly, raw alumina ceramic membrane (CM) was deposited with SiO2 active layer by situ hydrolysis deposition method. Subsequently, γ-methacryloxy propyl trimethoxyl silane (MPS) was used as a coupling agent to introduce double bonds onto the SiO2 layer (MPS-CM). Then, 1-vinylimidazole (VI) was employed as a functional monomer to graft-polymerization onto the MPS-CM (PVI-CM)...
March 9, 2017: Journal of Hazardous Materials
https://www.readbyqxmd.com/read/28342326/sex-dependent-mechanical-properties-of-the-human-mandibular-condyle
#15
Do-Gyoon Kim, Arman Haghighi, Hyun-Jung Kwon, Jessica S Coogan, Daniel P Nicolella, Trenton B Johnson, Hwan D Kim, Nari Kim, Amanda M Agnew
The mandibular condyle consists of articular cartilage and subchondral bone that play an important role in bearing loads at the temporomandibular joint (TMJ) during static occlusion and dynamic mastication. The objective of the current study was to examine effects of sex and cartilage on 1) static and dynamic mechanical analysis (DMA) based dynamic energy storage and dissipation for the cartilage-subchondral bone construct of the human mandibular condyle, and 2) their correlations with the tissue mineral density and trabecular morphological parameters of subchondral bone...
March 16, 2017: Journal of the Mechanical Behavior of Biomedical Materials
https://www.readbyqxmd.com/read/28342176/investigating-the-physiological-effects-of-10-5-tesla-static-field-exposure-on-anesthetized-swine
#16
Yigitcan Eryaman, Patrick Zhang, Lynn Utecht, Kivanc Kose, Russell L Lagore, Lance DelaBarre, Jeramy Kulesa, Lynn E Eberly, Gregor Adriany, Tinen L Iles, Paul A Iaizzo, J Thomas Vaughan, Kamil Ugurbil
PURPOSE: In this work, we investigated the relative effects of static magnetic field exposure (10.5 Tesla [T]) on two physiological parameters; blood pressure (BP) and heart rate (HR). METHODS: In vivo, we recorded both BP and HR in 4 swine (3 female, 1 male) while they were positioned within a 10.5T magnet. All measurements were performed invasively within these anesthetized animals by the placement of pressure catheters into their carotid arteries. RESULTS: We measured average increases of 2...
March 25, 2017: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
https://www.readbyqxmd.com/read/28341599/nucleo-cytoplasmic-transport-of-estrogen-receptor-alpha-in-breast-cancer-cells
#17
REVIEW
Angeles C Tecalco-Cruz, Issis A Pérez-Alvarado, Josué O Ramírez-Jarquín, Leticia Rocha-Zavaleta
Approximately 70% cases of breast cancers exhibit high expression and activity levels of estrogen receptor alpha (ERα), a transcription regulator that induces the expression of genes associated with cellular proliferation and survival. These nuclear functions of the receptor are associated with the development of breast cancer. However, ERα localization is not static, but rather, dynamic with continuous shuttling between the nucleus and the cytoplasm. Interestingly, both the nuclear import and export of ERα are modulated by several stimuli that include estradiol, antiestrogens, and growth factors...
March 21, 2017: Cellular Signalling
https://www.readbyqxmd.com/read/28341253/digital-workflow-for-a-dental-prosthesis-that-considers-lateral-mandibular-relation
#18
Ji-Hyun Park, Jong-Eun Kim, June-Sung Shim
Most digital prosthesis designs consider only the maximal intercuspal position (MIP) and not the lateral movement. During the computer-aided design and computer-aided manufacture (CAD-CAM) prosthesis delivery process, the clinician has to adjust the prosthesis to avoid occlusal interference during lateral excursion. The novel digital workflow described in this report can be divided into 2 steps. After obtaining interocclusal records for the MIP and the lateral excursion position, the crown CAD data were designed using a general digital workflow considering only the MIP...
March 2017: Journal of Prosthetic Dentistry
https://www.readbyqxmd.com/read/28341173/preparation-and-characterization-of-reinforced-papers-using-nano-bacterial-cellulose
#19
Taghi Tabarsa, Somayeh Sheykhnazari, Alireza Ashori, Mahd Mashkour, Abolghasem Khazaeian
The main goal of this work was to reinforce softwood pulp (SP) with bacterial cellulose (BC) to generate a sustainable biocomposite. BC is a nanocellulose, which was anticipated to increase interfacial adhesion between the cellulosic fibers and BC. The organism used was Gluconacetobacter xylinus, which was incubated in a static Hestrin-Schramm culture at 28°C for 14 days. The specimens of BC, SP and the reinforced SP with BC were characterized using X-ray diffraction (XRD), FT-IR, FESEM, and physico-mechanical testing...
March 21, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28340850/from-static-to-dynamic-risk-prediction-time-is-everything
#20
EDITORIAL
Tom Greene, Liang Li
No abstract text is available yet for this article.
April 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
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